LOCUS       DAVHSY010000001       128070 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.001, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000001 DAVHSY010000000
VERSION     DAVHSY010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 128070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 128070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..128070
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.001"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            92..526
                     /locus_tag="VVR43_000001"
     CDS             92..526
                     /locus_tag="VVR43_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6148432.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            538..1728
                     /locus_tag="VVR43_000002"
     CDS             538..1728
                     /locus_tag="VVR43_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEU6148433.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            1739..2230
                     /locus_tag="VVR43_000003"
     CDS             1739..2230
                     /locus_tag="VVR43_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU6148434.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            2245..3024
                     /locus_tag="VVR43_000004"
     CDS             2245..3024
                     /locus_tag="VVR43_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU6148435.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            3011..3829
                     /locus_tag="VVR43_000005"
     CDS             3011..3829
                     /locus_tag="VVR43_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6148436.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            3829..4122
                     /locus_tag="VVR43_000006"
     CDS             3829..4122
                     /locus_tag="VVR43_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU6148437.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTFGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIHVEKESVMGKTKELLFK"
     gene            4144..6045
                     /locus_tag="VVR43_000007"
     CDS             4144..6045
                     /locus_tag="VVR43_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU6148438.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYLVEGDKSYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGMHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEVLTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            6105..7106
                     /locus_tag="VVR43_000008"
     CDS             6105..7106
                     /locus_tag="VVR43_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6148439.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYVHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(7216..7551)
                     /locus_tag="VVR43_000009"
     CDS             complement(7216..7551)
                     /locus_tag="VVR43_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148440.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(7562..7804)
                     /locus_tag="VVR43_000010"
     CDS             complement(7562..7804)
                     /locus_tag="VVR43_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148441.1"
                     /translation="MKKEKRQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(7815..8357)
                     /locus_tag="VVR43_000011"
     CDS             complement(7815..8357)
                     /locus_tag="VVR43_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEU6148442.1"
                     /translation="MKKETFTEKLIKRTYSISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLRILIGEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(8373..8567)
                     /locus_tag="VVR43_000012"
     CDS             complement(8373..8567)
                     /locus_tag="VVR43_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6148443.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            8733..9683
                     /gene="rsmH"
                     /locus_tag="VVR43_000013"
     CDS             8733..9683
                     /gene="rsmH"
                     /locus_tag="VVR43_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU6148444.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            9695..10012
                     /gene="ftsL"
                     /locus_tag="VVR43_000014"
     CDS             9695..10012
                     /gene="ftsL"
                     /locus_tag="VVR43_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU6148445.1"
                     /translation="MAERMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            10016..12268
                     /locus_tag="VVR43_000015"
     CDS             10016..12268
                     /locus_tag="VVR43_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEU6148446.1"
                     /translation="MKWTKKVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGSKGNGITY
                     ANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDVYTTLSSPLQSFMETQ
                     MDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEGITEDFVWRDILYQSNYE
                     PGSAMKVMTLASSIDNNTFPSGEYFNSSEFKIADATTRDWDVNEGLTTGGMMTFLQGF
                     AHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIVSIAQSSF
                     GQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGKPVSEDTA
                     SLTRTNMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLVGST
                     NYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSPA
                     KNLDQVTTESSYAMPSIKDISPGDLAEALRRNIVQPIVVGTGTKIKETSVEEGKNLAP
                     NQQVLLLSDKVEEIPDMYGWTKATAEAFSKWLNIELVFEGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            12270..13250
                     /locus_tag="VVR43_000016"
     CDS             12270..13250
                     /locus_tag="VVR43_000016"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU6148447.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLIASVLVAFFFALFSNQLSNNVGMILFILVLYGLIGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGIDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFVFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIIYVFETTSVMMQVGYFKMTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            13859..15964
                     /locus_tag="VVR43_000017"
     CDS             13859..15964
                     /locus_tag="VVR43_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU6148448.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPELLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKV"
     gene            complement(16260..16742)
                     /locus_tag="VVR43_000018"
     CDS             complement(16260..16742)
                     /locus_tag="VVR43_000018"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU6148449.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(16837..18321)
                     /locus_tag="VVR43_000019"
     CDS             complement(16837..18321)
                     /locus_tag="VVR43_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU6148450.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            18474..20081
                     /locus_tag="VVR43_000020"
     CDS             18474..20081
                     /locus_tag="VVR43_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU6148451.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTDQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            20246..20413
                     /locus_tag="VVR43_000021"
     CDS             20246..20413
                     /locus_tag="VVR43_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEU6148452.1"
                     /translation="MKKRILSAGLTFAAALLLAACGQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(20406..20927)
                     /locus_tag="VVR43_000022"
                     /pseudo
     CDS             complement(20406..20927)
                     /locus_tag="VVR43_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            21150..22595
                     /locus_tag="VVR43_000023"
     CDS             21150..22595
                     /locus_tag="VVR43_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU6148453.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVYFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLMSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEHPDYASKIKKIYTKGFTKKVEAP
                     KTSKDQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGVDVYNDQ
                     DFTSLHGKFHFPVGNVHLDSEQALGFVRERYSLADGDHDRGRNQQKVIAAILQKLTSS
                     EALKNYSRIIDSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGMGRTDLPSY
                     AMPDSNLYMMEINDSSLASVKTAIQDMLEGR"
     gene            22597..23328
                     /gene="cps4B"
                     /locus_tag="VVR43_000024"
     CDS             22597..23328
                     /gene="cps4B"
                     /locus_tag="VVR43_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HEU6148454.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTSDVLDKLEKNRIPTLNNS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELINMGCYT
                     QVNSSHVLKSKLFGERYKFMKKRAQYFLERDLVHIIASDMHNVDSRPPHMAEAYDLVS
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            23337..24029
                     /gene="cpsC"
                     /locus_tag="VVR43_000025"
     CDS             23337..24029
                     /gene="cpsC"
                     /locus_tag="VVR43_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEU6148455.1"
                     /translation="MKEQNTIEIDVFQLLKTLWKHKLIILLVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGTYLVKDYREIILSQDVLEKVATNLKLD
                     IPAKTLTSKVQVTVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIIAVTRVSDVT
                     TLEEARPAMTPSSPNVRRNTLVGFLGGAAVTVITVLLIELLDTRVKRPEDVEDVLQMP
                     LLGVVPDFDKMK"
     gene            24039..24728
                     /locus_tag="VVR43_000026"
     CDS             24039..24728
                     /locus_tag="VVR43_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEU6148456.1"
                     /translation="MPTLEISQAKLELVKKAEEYYNALCTNLQLSGDDLKVFSITSVK
                     AGEGKTTTSTNIAWAFARAGYKTLLIDADMRNSVMSGVFKSRERITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIVVDTPPVGVVI
                     DAAIIMQKCDASILVTKAGETKRRDLQKAKEQLEQTGKSCLGVVLNKLDTSVEKYGSY
                     GSYGNYRKQKK"
     gene            24743..26104
                     /locus_tag="VVR43_000027"
     CDS             24743..26104
                     /locus_tag="VVR43_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU6148457.1"
                     /translation="MSEKLAKPSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYIL
                     HYFVFYISDYGRNFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LLLHVFLVYVLNPFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNDVVGEL
                     VAVSVLDKPDFQHDDLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDWARNKQICEMAGLNVVTFSTTFYKTSHVIAKRIIDIVGSLVGLILCG
                     LVSIVLVPLIRKDGGSAFFAQTRIGKNGRHFTFYKFRSMCVDAEEKKRELMEQNTMQG
                     GMFKVDDDPRITKIGHFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQK
                     RRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDGWTIWKDIEILLKTVKVVLMKD
                     GAK"
     gene            26110..26853
                     /locus_tag="VVR43_000028"
     CDS             26110..26853
                     /locus_tag="VVR43_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001005725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HEU6148458.1"
                     /translation="MNERIQILGITIDPLTMKETVDAVEQYVLKKHPLHLMGVNADKI
                     NQCYEDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMKHLLELSNEKG
                     YSVYFFGAKEDVLQDMLKIFEERYPALNVVGYRNGYFSPEDEKHIQEDIKEKKPDFVF
                     VGITSPKKEYIIQSFMDNGINAVFMGVGGSFDVLSGHIKRAPLWMQNAHLEWLFRVAN
                     EPKRLFKRYFVGNVSFIRKVLRAKRGYKL"
     gene            26850..27674
                     /locus_tag="VVR43_000029"
     CDS             26850..27674
                     /locus_tag="VVR43_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HEU6148459.1"
                     /translation="MNQTEIVKLIQKVELDAIKEFQKICKENNIDFFLRGGSVLGAVK
                     YDGFIPWDDDMDIAVPREGYDKLPGIFKDRIIAGKYQVLAYQYCDTLHCYFPRLFLLE
                     DERKRLGLPRNTNLGLHLIDIIPLDGAPNHSFLRKLYFGKVYWYRFLASLGTTYVGDH
                     VDMHSAKQKLIIGFFKKLGFAKLFPQNYVYRRLDNLYKKYDWKKQKYAGTINASLFAK
                     EVMPVEIWGEGVEKPFEDAFFKVPTEYDRYLKRLYGENYLHEEPSDDEKKSHLGGQ"
     gene            27676..28554
                     /locus_tag="VVR43_000030"
     CDS             27676..28554
                     /locus_tag="VVR43_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6148460.1"
                     /translation="MFCYIILHYKVLEETISCVKSIKEGNSNTKQIVIIDNFSNNGTG
                     EKLQELYESDSEIDVLINHENAGFARGNNVAYQFAKEKYKPDFMVIMNNDIEIETEEF
                     EKIVTDIYRKEKFHLLGPDIFSTTYQLHQNPKRLTHYTYEEVKALNEKFKKGSQVSLA
                     LKIKCWLKSSKVLRTAIYQNRRKKKSVDYRKQVENPILHGSFIVYSRDFIEKEEYAFN
                     PNTFFYYETEILDYEAELKGYKRIYTPKIKVLHHQNVATNQVYTNLVEKTLFSNKCNF
                     ESTSYFLKLMKENEGV"
     gene            28555..29889
                     /locus_tag="VVR43_000031"
     CDS             28555..29889
                     /locus_tag="VVR43_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HEU6148461.1"
                     /translation="MTYLFLLCLTLFLLTFFYFFAFNQDLIAPPVVMSVMFLISSVFA
                     LINVQNWNIEYSGLAYLLIISGIIVFSMPLLALNSPSLNTKIKVTDRLIDIQFWKIAL
                     TIIVDLVILYLYRREIHNLALSHGYTGSNFQWFFRNATSYEGELTVRTSIRVLIRIID
                     VSAYIFGYTFINNFFIYSHKRSKDLLLLVPFLIFISKTLLSGGRLDIIKILIAYVVMA
                     YIQQKRKVGWDKVISHKYMRLGFVGLIAGIPTFYYSLFLSGRSTTRTVFESISTYLGG
                     SIQHFNQYIQNPIGVAEVFGDESFVAIMNILGNLGFVNYNSTVHLEFRQLGITMGNVY
                     TFFRRPWHDFGLVGMYIFSFVVGVFFAIFYLKLRKSRAGFKLDIHTIIYSYFFYWIFL
                     SSIEQYSFTTISLFTLVFIVLVYLMAFFYWNLDFHRGKLVIKLSDTSIKSEN"
     gene            29917..31341
                     /locus_tag="VVR43_000032"
     CDS             29917..31341
                     /locus_tag="VVR43_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148462.1"
                     /translation="MNSKIKNILTNFSYVISSNLLTVLTSSLVVLIFPKLMGVTEYSY
                     WQLYIFYLTYIGFFHLGWIDGIYLKYGGLEYNNLDRKQFYSQMILFSSFLMIISLLLF
                     GLNVLAVTDSNARYIYNMTIISMIITNLRTLYVYVLQMTNRLKDSSIILLSDRVLYVL
                     LLFLFIVFGWHEYKVMILADILGRSFSLILSFWICKDIVFQPLSKFIFNIKESFDNIR
                     VGINLMLSNIASSLIIGIVRLGIQWNWNIETFGKVSLTLSVSNLLMTFINAIGLVVFP
                     LLRRTKAENLPKIYSNLRNVLMLIMFAILLIYYPLKIVLDLWLPAYQDALIFMTLIFP
                     MSVYEGKMALVINTYLKALRMERDILRVNALVMLISMGVTLVTTYLLNSLELTVVSIV
                     VLLALRSIIAELILSKKLDVSVKKDIVLEFLLTLVFISSSWYLPIGLAVIVYTIAYGL
                     YLYLKHEDIKTYLAYFKASKKTSN"
     gene            31406..32494
                     /gene="wecB"
                     /locus_tag="VVR43_000033"
     CDS             31406..32494
                     /gene="wecB"
                     /locus_tag="VVR43_000033"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HEU6148463.1"
                     /translation="MKKIMLVFGTRPEAIKMCPLVNELKKHEDMETIVCVTGQHKEMV
                     SPVLDLFGVVPDYDLEIMKANQTLFSITTSILEKIKPVLEKEQPDIVLVHGDTTTTYA
                     AALAAFYLGIKVGHVEAGLRTYNLQSPFPEEFNRQSTSIIATYHFAPTELAKENLLKE
                     GRENVYVTGNTVIDALTTTVQEDYTHTHLDLNANNRLILLTAHRRENLGEPMRHMFRA
                     VKRVLNEYEDVKVIYPIHKNPLVRETAAEIFGDTERIQIIEPLDVLDFHNFMNQSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVAAGTLKLVGTDEETIYQNFKLLLDDSG
                     EYKKMSQASNPYGNGDASQQIVQILRGI"
     gene            32657..33526
                     /gene="rfbA"
                     /locus_tag="VVR43_000034"
     CDS             32657..33526
                     /gene="rfbA"
                     /locus_tag="VVR43_000034"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEU6148464.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFKDLLLDGSEFGIKLSYAEQPSPDGLAQAFLIGEEFIGDDSV
                     ALILGDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEK
                     PEYPRSNYAVTGLYFYDNDVVEIAKQIKPSARGELEITDVNKAYLNRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEISYRMGYISREDVLELAQPLKKN
                     EYGQYLLRLIGEA"
     gene            33527..34120
                     /locus_tag="VVR43_000035"
     CDS             33527..34120
                     /locus_tag="VVR43_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEU6148465.1"
                     /translation="MSDNFFGKTLVVRKIDAIPGLLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAAGKLQNNVSFSRKNVLRGLHAEPWDKYISVADDGKVLGSWVDLREG
                     ETFGNVYQTEIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPALGIEWENLAEAEVSEADKHHPLLRDVKPLTKDEL"
     gene            34132..35181
                     /gene="rfbB"
                     /locus_tag="VVR43_000036"
     CDS             34132..35181
                     /gene="rfbB"
                     /locus_tag="VVR43_000036"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEU6148466.1"
                     /translation="MTEYKKIIVTGGAGFIGSNFVHYVYNNFTDVHVTVLDKLTYAGN
                     RANIEEILGDRVELVVGDIADAALVDKLAAEADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDLRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQPAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQDWWKAEKE
                     AVEANYAKTQEIITV"
     gene            35247..36098
                     /gene="rfbD"
                     /locus_tag="VVR43_000037"
     CDS             35247..36098
                     /gene="rfbD"
                     /locus_tag="VVR43_000037"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEU6148467.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTENVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQSLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            36161..36495
                     /locus_tag="VVR43_000038"
                     /pseudo
     CDS             36161..36495
                     /locus_tag="VVR43_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272501.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding protein"
     gene            36762..37347
                     /locus_tag="VVR43_000039"
                     /pseudo
     CDS             36762..37347
                     /locus_tag="VVR43_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835598.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            37584..39566
                     /locus_tag="VVR43_000040"
     CDS             37584..39566
                     /locus_tag="VVR43_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6148468.1"
                     /translation="MKSSRLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            39867..45170
                     /locus_tag="VVR43_000041"
     CDS             39867..45170
                     /locus_tag="VVR43_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU6148469.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGSVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKIRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPRAKVVITEDANADKKVDWQDGAIAYRSIMNNPKGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLPTDKEKMYYFNTQTGATTWTLPSDWAESKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FESLDAPAQPGEGLENAFDGNLSSLWHTSWGGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTTTDWPDNNKSKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASDQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(45336..47495)
                     /locus_tag="VVR43_000042"
     CDS             complement(45336..47495)
                     /locus_tag="VVR43_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEU6148470.1"
                     /translation="MNKQTILRIAKYVSICFLTLFITAVMLGGGIFLYYVSKAPALSE
                     SKLVATTSSKIFDSKNELIADLGSERRVNAQANEIPTDLVKAIVSIEDHRFFDHRGVD
                     TIRIIGAFLRNLQNNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAVQLEQK
                     ATKQEILTYYVNKVYMSNGNYGMQTAAQNYYGKDLRELSLPQLALLAGMPQAPNQYDP
                     YSHPEAALDRRNLVLSEMKGQGYISAEQYEKAINTPITDGLQSLKSVNSYPAYMDNYL
                     KEVIDQVEQETGYNLLTTGMDVYTNVDQEAQKHLWDIYNSDQYVSYPDDDLQVASTVV
                     DVSNGKVIAQLGARHQASNVSFGTNQAVETNRDWGSSMKPITDYAPALEYGVYDSTAS
                     IVHDVPYNYPGTDTPLYNWDHVYFGNITIQYALQQSRNVTAVETLNKVGLDRAKTFLN
                     GLGIDYPSMHYANAISSNTTESNKKYGASSEKMAAAYAAFANGGIYHKPMYINKIVFS
                     DGSEKEFSDAGTRAMKETTAYMMTEMMKTVLTYGTGRGAYLPWLPQAGKTGTSNYTDE
                     EIEKYIKNTGYVAPDEMFVGYTRKYSMAVWTGYSNRLTPIVGDGFLVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(47492..48088)
                     /gene="recU"
                     /locus_tag="VVR43_000043"
     CDS             complement(47492..48088)
                     /gene="recU"
                     /locus_tag="VVR43_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU6148471.1"
                     /translation="MVNYPHKLSSQKRQPSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVRVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEAKETKQ
                     KRAIPMKNFHPHQIQHMEQILAQQGICFVLLHFSSQQETYLLPAYDLIRFYHQDKGQK
                     SMPLGYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            48155..48682
                     /locus_tag="VVR43_000044"
     CDS             48155..48682
                     /locus_tag="VVR43_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU6148472.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGTLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            48752..49093
                     /gene="gpsB"
                     /locus_tag="VVR43_000045"
     CDS             48752..49093
                     /gene="gpsB"
                     /locus_tag="VVR43_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU6148473.1"
                     /translation="MTSIIFSAKDIFEQEFGREVRGYSKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPQVSSAPSPSHPDPIDVAASSSMTNFDILKRLNRLEKEV
                     FGKQILDNTDL"
     gene            49114..49494
                     /gene="rnpB"
                     /locus_tag="VVR43_000046"
     ncRNA           49114..49494
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VVR43_000046"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            49579..50736
                     /locus_tag="VVR43_000047"
     CDS             49579..50736
                     /locus_tag="VVR43_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU6148474.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWVSDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYSEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            50749..52143
                     /gene="mapZ"
                     /locus_tag="VVR43_000048"
     CDS             50749..52143
                     /gene="mapZ"
                     /locus_tag="VVR43_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU6148475.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLS
                     EDSILDKYVKQHRDEIEADKFATRQYKKEELVETQSLDDLIQEMREAVEESEAYSEEV
                     PSSEDILPPLPLDDEEQGLDPLLLEDENPTEMTEEVEEEQNLSRLEQEESEKKSKKGF
                     VLTALALVSVIICVSAYYVYRQVNRSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSETSSSSTS
                     QTSSNTTSETSPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            52219..53643
                     /gene="gndA"
                     /locus_tag="VVR43_000049"
     CDS             52219..53643
                     /gene="gndA"
                     /locus_tag="VVR43_000049"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU6148476.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEVS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            53655..54344
                     /locus_tag="VVR43_000050"
     CDS             53655..54344
                     /locus_tag="VVR43_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6148477.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            54442..55404
                     /gene="cbpC"
                     /locus_tag="VVR43_000051"
     CDS             54442..55404
                     /gene="cbpC"
                     /locus_tag="VVR43_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU6148478.1"
                     /translation="MKILKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDGGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYVVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWYQDGSTWYYLDPSN
                     GDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            55423..56421
                     /gene="cbpJ"
                     /locus_tag="VVR43_000052"
     CDS             55423..56421
                     /gene="cbpJ"
                     /locus_tag="VVR43_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEU6148479.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWLVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNNWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQYLGNKWYYLRSSGAMVTGW
                     YQDGLTWYYLNAGNGDMKTGWFQVNGKWYYAYSSGALAVNTTVDGYYVNYNGEWVR"
     gene            complement(56539..57771)
                     /locus_tag="VVR43_000053"
     CDS             complement(56539..57771)
                     /locus_tag="VVR43_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6148480.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLAMLSIIIS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(57930..58400)
                     /locus_tag="VVR43_000054"
     CDS             complement(57930..58400)
                     /locus_tag="VVR43_000054"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148481.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            complement(58300..58658)
                     /locus_tag="VVR43_000055"
                     /pseudo
     CDS             complement(58300..58658)
                     /locus_tag="VVR43_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
     gene            59321..59650
                     /locus_tag="VVR43_000056"
     CDS             59321..59650
                     /locus_tag="VVR43_000056"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6148482.1"
                     /translation="MIRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWAQ"
     gene            59772..60650
                     /gene="mvk"
                     /locus_tag="VVR43_000057"
     CDS             59772..60650
                     /gene="mvk"
                     /locus_tag="VVR43_000057"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU6148483.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            60632..61585
                     /gene="mvaD"
                     /locus_tag="VVR43_000058"
     CDS             60632..61585
                     /gene="mvaD"
                     /locus_tag="VVR43_000058"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU6148484.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            61572..62579
                     /locus_tag="VVR43_000059"
     CDS             61572..62579
                     /locus_tag="VVR43_000059"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU6148485.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            62563..63573
                     /locus_tag="VVR43_000060"
     CDS             62563..63573
                     /locus_tag="VVR43_000060"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU6148486.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            63650..64348
                     /locus_tag="VVR43_000061"
     CDS             63650..64348
                     /locus_tag="VVR43_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU6148487.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            64345..65340
                     /locus_tag="VVR43_000062"
     CDS             64345..65340
                     /locus_tag="VVR43_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6148488.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTETLQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            65354..65986
                     /locus_tag="VVR43_000063"
     CDS             65354..65986
                     /locus_tag="VVR43_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6148489.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            65987..66229
                     /locus_tag="VVR43_000064"
     CDS             65987..66229
                     /locus_tag="VVR43_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU6148490.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            66154..66465
                     /locus_tag="VVR43_000065"
     CDS             66154..66465
                     /locus_tag="VVR43_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU6148491.1"
                     /translation="MDWDFADTCWEKDPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSLWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            66490..66756
                     /locus_tag="VVR43_000066"
                     /pseudo
     CDS             66490..66756
                     /locus_tag="VVR43_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            66906..67145
                     /locus_tag="VVR43_000067"
     CDS             66906..67145
                     /locus_tag="VVR43_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148492.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            67190..67819
                     /locus_tag="VVR43_000068"
     CDS             67190..67819
                     /locus_tag="VVR43_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEU6148493.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPAVSPSQELFGKIKVKEVRYLKEFRNLNSKNAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     SAVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            68118..68477
                     /locus_tag="VVR43_000069"
     CDS             68118..68477
                     /locus_tag="VVR43_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6148494.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            68671..69954
                     /locus_tag="VVR43_000070"
     CDS             68671..69954
                     /locus_tag="VVR43_000070"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU6148495.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     EDGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(70002..72368)
                     /locus_tag="VVR43_000071"
     CDS             complement(70002..72368)
                     /locus_tag="VVR43_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU6148496.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIVGLSAKNREAFVSTLRLNYGTEMILAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEVRDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDTDFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDTEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDHATQHIGTARKTYLVERFSDLLKN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(72496..73110)
                     /gene="lepB"
                     /locus_tag="VVR43_000072"
     CDS             complement(72496..73110)
                     /gene="lepB"
                     /locus_tag="VVR43_000072"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU6148497.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            complement(73114..73995)
                     /locus_tag="VVR43_000073"
     CDS             complement(73114..73995)
                     /locus_tag="VVR43_000073"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU6148498.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGNRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            74082..74384
                     /gene="zapA"
                     /locus_tag="VVR43_000074"
     CDS             74082..74384
                     /gene="zapA"
                     /locus_tag="VVR43_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU6148499.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            74381..74929
                     /locus_tag="VVR43_000075"
     CDS             74381..74929
                     /locus_tag="VVR43_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU6148500.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            75033..77369
                     /locus_tag="VVR43_000076"
     CDS             75033..77369
                     /locus_tag="VVR43_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU6148501.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHATEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADRGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDIFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     regulatory      77533..77621
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            77712..79028
                     /locus_tag="VVR43_000077"
     CDS             77712..79028
                     /locus_tag="VVR43_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU6148502.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALTQS
                     AFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLMVL
                     LGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     gene            79246..79794
                     /locus_tag="VVR43_000078"
     CDS             79246..79794
                     /locus_tag="VVR43_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU6148503.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            79904..80803
                     /locus_tag="VVR43_000079"
     CDS             79904..80803
                     /locus_tag="VVR43_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU6148504.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMTQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(80828..82102)
                     /gene="serS"
                     /locus_tag="VVR43_000080"
     CDS             complement(80828..82102)
                     /gene="serS"
                     /locus_tag="VVR43_000080"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU6148505.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(82316..82687)
                     /locus_tag="VVR43_000081"
     CDS             complement(82316..82687)
                     /locus_tag="VVR43_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU6148506.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            complement(82690..84054)
                     /locus_tag="VVR43_000082"
     CDS             complement(82690..84054)
                     /locus_tag="VVR43_000082"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU6148507.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            84379..85164
                     /locus_tag="VVR43_000083"
     CDS             84379..85164
                     /locus_tag="VVR43_000083"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU6148508.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            85258..85692
                     /locus_tag="VVR43_000084"
     CDS             85258..85692
                     /locus_tag="VVR43_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU6148509.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGHLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            85692..86666
                     /locus_tag="VVR43_000085"
     CDS             85692..86666
                     /locus_tag="VVR43_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU6148510.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            86726..86950
                     /locus_tag="VVR43_000086"
     CDS             86726..86950
                     /locus_tag="VVR43_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU6148511.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            87069..88043
                     /gene="fabK"
                     /locus_tag="VVR43_000087"
     CDS             87069..88043
                     /gene="fabK"
                     /locus_tag="VVR43_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU6148512.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            88036..88956
                     /gene="fabD"
                     /locus_tag="VVR43_000088"
     CDS             88036..88956
                     /gene="fabD"
                     /locus_tag="VVR43_000088"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU6148513.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEATPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            88990..89721
                     /gene="fabG"
                     /locus_tag="VVR43_000089"
     CDS             88990..89721
                     /gene="fabG"
                     /locus_tag="VVR43_000089"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU6148514.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LSEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            89743..90978
                     /gene="fabF"
                     /locus_tag="VVR43_000090"
     CDS             89743..90978
                     /gene="fabF"
                     /locus_tag="VVR43_000090"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU6148515.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            90981..91466
                     /locus_tag="VVR43_000091"
     CDS             90981..91466
                     /locus_tag="VVR43_000091"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU6148516.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            91463..91885
                     /gene="fabZ"
                     /locus_tag="VVR43_000092"
     CDS             91463..91885
                     /gene="fabZ"
                     /locus_tag="VVR43_000092"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU6148517.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            91897..93264
                     /gene="accC"
                     /locus_tag="VVR43_000093"
     CDS             91897..93264
                     /gene="accC"
                     /locus_tag="VVR43_000093"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU6148518.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            93301..94167
                     /locus_tag="VVR43_000094"
     CDS             93301..94167
                     /locus_tag="VVR43_000094"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU6148519.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            94164..94931
                     /locus_tag="VVR43_000095"
     CDS             94164..94931
                     /locus_tag="VVR43_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU6148520.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            95194..95379
                     /gene="briC"
                     /locus_tag="VVR43_000096"
     CDS             95194..95379
                     /gene="briC"
                     /locus_tag="VVR43_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU6148521.1"
                     /translation="MTGTETFTVISTEDLEQTSSGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            95861..96097
                     /locus_tag="VVR43_000097"
     CDS             95861..96097
                     /locus_tag="VVR43_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6148522.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(96147..96569)
                     /gene="nusB"
                     /locus_tag="VVR43_000098"
     CDS             complement(96147..96569)
                     /gene="nusB"
                     /locus_tag="VVR43_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU6148523.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(96562..96951)
                     /locus_tag="VVR43_000099"
     CDS             complement(96562..96951)
                     /locus_tag="VVR43_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU6148524.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            complement(96973..97533)
                     /gene="efp"
                     /locus_tag="VVR43_000100"
     CDS             complement(96973..97533)
                     /gene="efp"
                     /locus_tag="VVR43_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU6148525.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            97656..97886
                     /locus_tag="VVR43_000101"
     CDS             97656..97886
                     /locus_tag="VVR43_000101"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148526.1"
                     /translation="MVNVKEYPLYFFSYSMEIKEQTRKLAAGCSKHCFEVVDRTDEVS
                     NHIYGNVTLTWSEEIFEEYYISKGRSKFTPTC"
     gene            complement(97911..98954)
                     /locus_tag="VVR43_000102"
     CDS             complement(97911..98954)
                     /locus_tag="VVR43_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HEU6148527.1"
                     /translation="MATMKAARWHAAKDVRIQEIEVPEVLPHQVKVAVKFTGICGTDL
                     HEFLDGPIFIPTDEHVYSGQKAPVTLGHEFSGEIIEVGSDVTRVKVGDRVAVEPILAK
                     NNLVGDYNLDPNLNFVGLAADGGFAKYCVLDGDLVHVIPDSLSYEQAALTEPAAVAVY
                     AVRQSSLKAGDTAVVFGLGPIGLLIVEALRAAGASKIYAVELSPERQAKAEELGAIVV
                     RPEEGETAVEAIHRLTNGGVDVSYEVTGVPVVLGQALAAVHKAGECMVVSIWEREANI
                     NPNEFAIQEKTLKGIIAYRHIFPKVLELMEQGYFSAEKLVTKKIKLENIVEEDFIELT
                     QDKSQIKILVEPE"
     gene            complement(99078..100520)
                     /gene="gatB"
                     /locus_tag="VVR43_000103"
     CDS             complement(99078..100520)
                     /gene="gatB"
                     /locus_tag="VVR43_000103"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU6148528.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            complement(100520..101986)
                     /gene="gatA"
                     /locus_tag="VVR43_000104"
     CDS             complement(100520..101986)
                     /gene="gatA"
                     /locus_tag="VVR43_000104"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU6148529.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKHSEETIYQVAAAFEATTGYHKQQPVIFGGDN"
     gene            complement(101986..102288)
                     /gene="gatC"
                     /locus_tag="VVR43_000105"
     CDS             complement(101986..102288)
                     /gene="gatC"
                     /locus_tag="VVR43_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU6148530.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGIDRDRLFKNVPEKDNYYIKVPAILDNGGDA"
     gene            102501..104045
                     /locus_tag="VVR43_000106"
     CDS             102501..104045
                     /locus_tag="VVR43_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU6148531.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVNPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            104472..104670
                     /locus_tag="VVR43_000107"
                     /pseudo
     CDS             104472..104670
                     /locus_tag="VVR43_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
     gene            104781..104957
                     /locus_tag="VVR43_000108"
     CDS             104781..104957
                     /locus_tag="VVR43_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEU6148532.1"
                     /translation="MDLDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     NGMWRAENVTQDLI"
     gene            105073..105261
                     /locus_tag="VVR43_000109"
     CDS             105073..105261
                     /locus_tag="VVR43_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU6148533.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            105418..105783
                     /locus_tag="VVR43_000110"
     CDS             105418..105783
                     /locus_tag="VVR43_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU6148534.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            105786..107453
                     /locus_tag="VVR43_000111"
     CDS             105786..107453
                     /locus_tag="VVR43_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU6148535.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            107653..109353
                     /locus_tag="VVR43_000112"
     CDS             107653..109353
                     /locus_tag="VVR43_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU6148536.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            109346..109822
                     /gene="ilvN"
                     /locus_tag="VVR43_000113"
     CDS             109346..109822
                     /gene="ilvN"
                     /locus_tag="VVR43_000113"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU6148537.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            109888..110910
                     /gene="ilvC"
                     /locus_tag="VVR43_000114"
     CDS             109888..110910
                     /gene="ilvC"
                     /locus_tag="VVR43_000114"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU6148538.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            111017..111253
                     /locus_tag="VVR43_000115"
     CDS             111017..111253
                     /locus_tag="VVR43_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148539.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKY"
     gene            111491..111847
                     /locus_tag="VVR43_000116"
     CDS             111491..111847
                     /locus_tag="VVR43_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU6148540.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEIFGDE"
     gene            111897..113147
                     /gene="ilvA"
                     /locus_tag="VVR43_000117"
     CDS             111897..113147
                     /gene="ilvA"
                     /locus_tag="VVR43_000117"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU6148541.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            114018..114233
                     /locus_tag="VVR43_000118"
     CDS             114018..114233
                     /locus_tag="VVR43_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148542.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(114342..115082)
                     /locus_tag="VVR43_000119"
     CDS             complement(114342..115082)
                     /locus_tag="VVR43_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6148543.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(115082..116647)
                     /locus_tag="VVR43_000120"
     CDS             complement(115082..116647)
                     /locus_tag="VVR43_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU6148544.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYVSAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            116785..118674
                     /locus_tag="VVR43_000121"
     CDS             116785..118674
                     /locus_tag="VVR43_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU6148545.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVMDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNLFADYKVSDSLYRGA
                     KAADEKRIQARGIQLKSSFEAVLKEMQEGVRKRVVFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            complement(118975..119843)
                     /locus_tag="VVR43_000122"
                     /pseudo
     CDS             complement(118975..119843)
                     /locus_tag="VVR43_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            120099..120944
                     /locus_tag="VVR43_000123"
     CDS             120099..120944
                     /locus_tag="VVR43_000123"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU6148546.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(121091..122152)
                     /gene="dinB"
                     /locus_tag="VVR43_000124"
     CDS             complement(121091..122152)
                     /gene="dinB"
                     /locus_tag="VVR43_000124"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU6148547.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAENFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TILSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            122500..124824
                     /gene="pflB"
                     /locus_tag="VVR43_000125"
     CDS             122500..124824
                     /gene="pflB"
                     /locus_tag="VVR43_000125"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU6148548.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIDPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDKYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(124882..126144)
                     /locus_tag="VVR43_000126"
     CDS             complement(124882..126144)
                     /locus_tag="VVR43_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU6148549.1"
                     /translation="MEHINHTTLLIGIKDKNITLNKAIQHDTHIEVFATLDYHPPKCK
                     HCKGKQIKYDFQKPSKIPFIEIGGFPSLIHLKKRRFQCKSCRKVTVAETTLVQKNCQI
                     SEMVRQKIAQLLLNREALTHIASKLAISTSTSTVYRKLKQFHFQEDYTTLPEILSWDE
                     FSYQKGKLAFIAQDFNTKKIMTILDNRRQTTIRNHFFKYSKEARKKVKVVTVDMSGSY
                     IPLIKKLFPNAKIVLDRFHIVQHMSRALNQTRINIMKQFDDKSLEYRALKYYWKFILK
                     DSRKLSLKPFYARTFRETLTPRECLKKIFTLVPELKDYYDLYQLLLFHLQEKNTDQFW
                     GLIQDTLPHLNRTFKTTLSTFIRYKNYITNAIELPYSNAKLEATNKLIKDIKRNAFGF
                     RNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(126409..127938)
                     /gene="rlrA"
                     /locus_tag="VVR43_000127"
     CDS             complement(126409..127938)
                     /gene="rlrA"
                     /locus_tag="VVR43_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus transcriptional regulator RlrA"
                     /protein_id="HEU6148550.1"
                     /translation="MLNKYIEKRITDKITILNILLDIRSIELDELSTLTSLQSKSLLS
                     ILQELQETFEEELTFNLDTQQVQLIEHHSHQTNYYFHQLYNQSTILKILRFFLLQGNQ
                     SFNEFTQKEYISIATGYRVRQKCGLLLRSVGLDLVKNQVVGPEYRIRFLIALLQFHFG
                     IEIYDLNDGSMDWVTHMIVQSNSQLSHELLEITPDEYVHFSILVALTWKRREFPLEFP
                     ESKEFEKLKNLFMYPILMEHCQTYLEPHANMTFTQEELDYIFLVYCSANSSFSKDKWN
                     QEKKTHTIQLILQHTRGKHLLSKFKNILGNDISNSLSFLTALTFLTRTFLFGLQNLVP
                     YYNYYEHYGIESDKPLYHISKAIVQEWMTEQKIEGVIDQHRLYLFSLYLTETIFSSLP
                     AIPIFIILNNQADVNLIKSIILRNFTDKVASVTGYNILISPPPSEEHLTEPLIIITTK
                     EYLPYVKKQYPKGKHHFLTIALDLHVSQQRLIYQTIVDIRKEAFDKRVAMIAKKAHYL
                     L"
BASE COUNT        38460 a        23205 c        28559 g        37846 t
ORIGIN      
        1 tttttaaaaa aactattgac aagataaaaa taaaggatta caatggggga tataaagtaa
       61 accggtaaac ctaaacaaga aaggagaaaa gatgaaaatt gtacttgtag ggcatggaca
      121 ttttgctaca gggatttata gttctttaca attgattgca ggcaatcaag aaaatgtgga
      181 ggcgattgac tttgtggaag gaatgtcagc agatgaactc aagcaaaaaa tcttacttgc
      241 aatttcaaat gaagaagaag ttttaatcct aagtgatctc ttgggaggat cgccattcaa
      301 ggtttcttct accataatgg gagaaaatcc agccaaaaca atgaatgttc tttcgggttt
      361 gaacttagcc atgttaatgg aagcagtctt tgctagaatg gctcatagct ttgatgaggt
      421 tgttaataaa tcagtagtgg cggcccaggg cggagtcgta aatggtaaag aattgttttc
      481 aacggatgca gaggaagagg aagaagattt cgaatcgggt atttaaaggg taaaagaatg
      541 ataaaaaagg ttacgattga aaaaataaaa tcgcctgagc gcttcttaga agtaccactt
      601 ctgacgaaag aagaagtcgg ccaggcaatc gataaggtta ttcggcagtt agaactcaac
      661 cttgactatt tcaaggaaga tttcccgacg ccagctacct ttgataatgt ctatccaatc
      721 atggataaca cggaatggac caatggtttc tggacaggag aactgtggtt ggcttatgaa
      781 tacagtcaac aggatgcatt taaaaacatc gctcataaaa atgttctttc tttcctggat
      841 cgtgtcaata agagagtaga attggatcac catgatctcg gcttcttgta cacaccgtct
      901 tgtatggctg aatataagat aaatggagat ggagaggcta gagaagcaac cttgaaagct
      961 gcagataagt tgattgaacg ctatcaagaa aaaggtggtt ttattcaagc ttggggagac
     1021 ttgggcaaga aagagcatta ccgtttgatt atcgactgct tgctcaatat ccaactctta
     1081 ttctttgctt atcaagaaac aggcgatcaa aaatactacg atattgcaga aagtcatttc
     1141 tatgcttcag ctaataatgt aatccgtgat gacgcttcgt ccttccacac cttctatttt
     1201 gatcctgaga caggtcaacc ctttaaaggt gtaacgagac aagggtatag tgatgattca
     1261 tgctgggcac gtggtcaatc atggggagtc tatggtattc ctttgactta tcgtcactta
     1321 aaagacgagt cctgctttga cttgtttaag ggtgtgacca attatttctt gaatcgtctg
     1381 ccaaaagatc atgtgtccta ttgggatttg atttttaatg atggtagtgc tcaatcacga
     1441 gattcttcag caacagctat cgccgtctgt gggattcatg aaatgctaaa acatctccca
     1501 gaggtggatg ctgacaaaga tatttataaa catgctatgc atgccatgct tcgttccttg
     1561 atcgaacatt atgcaaatga tcaatttacc cctggtggga caagtctcct ccacggtgtg
     1621 tactcatggc attcaggtaa aggagtggat gaaggcaata tctggggtga ctactattac
     1681 ctagaagccc ttatccgttt ctacaaagac tggaacctat attggtagga ggagaaatat
     1741 gacaatgcca aatattatta tgacccgtat cgatgaacgg ttgattcatg gacaaggaca
     1801 actttgggta aaatacctag gttgtaatac ggtcattgtt gccaatgacg aagtaagcac
     1861 ggacaagatg caacaaactc tgatgaaaac agttgtgcca gactcagttg ccatgcgttt
     1921 cttccctttg caaaaggtga ttgatatcat tcacaaggct aatcctgctc aaacgatctt
     1981 tatcgttgta aaggatgtaa aggacgcttt aaccttggta gaaggtggtg tccctatcaa
     2041 agaaatcaat attgggaaca ttcacaatgc ccctggtaaa gagcaagtga cacgctccat
     2101 cttcctgggt gaagaggaca aggcggccct caaggaatta agccaaactc atcaagtaac
     2161 atttaatacg aaaacaactc caacaggaaa tgatggagct gttcaagtca acattatgga
     2221 ctatatttaa aagaggagat cgttatgtcg attaatgtat ttcaagcgat tttaattgga
     2281 ttatggacag ctttctgttt tagtggaatg ctgttaggaa tttacaccaa tagatgtatt
     2341 gttctgtcat ttggtgtcgg aattattcta ggtgatctgc ctactgctct tgcaatggga
     2401 gctattggtg aattggctta tatgggattc ggtgttggtg ctggaggtac tgttccacca
     2461 aacccaatcg gacctggtat ctttggtacc ttgatggcta tcactagtgc tggtaaagtc
     2521 agtccagaag cggctcttgc cctctctact ccgattgctg tggcgattca attcttacaa
     2581 actttcgcct acactgtacg tgctggtgcg cctgaaacgg cgatgaagca cttgaaaaac
     2641 cataatttga agaaattcaa gttcactcta aatgcaacaa tttggttgtt tgcctttatt
     2701 ggatttacct tgggttgctt gggtgccctt tcaatggata ccttgttgaa actcgtagac
     2761 tacattccac cggtattgct tacaggtttg acagttgctg gtaaaatgct tccagctatc
     2821 ggttttgcga tgatcttgtc agtgatggct aagaaagagt tgattccctt tgtcttgttg
     2881 ggatatgttt gtgcagctta tctaaacatc ccaacaattg gtattgcaat tgtaggtact
     2941 atctttgctt tgattgaatt ttataacaag ccaaaaacag cggatcatgt ggtagaggag
     3001 gaagcacacg atgactggat ctaacaaatt aacaaaacgt gattatctta aaacgtcttt
     3061 gcgggcattc ttttgtcaaa atggatttaa ctatagtaac tatcaagggt tgggatatgc
     3121 caatgtgatg tatcctgctt tgaaaaaaca ctatggagag gatcaggaag gtttctacca
     3181 agccttggaa gaaaactgtg aattctataa taccaaccca cacttcctgc cttttattac
     3241 cagcttgcat cttgtaatgt tggaaaatgg ccgtccggca aaagaaacac gtagcatcaa
     3301 gatggccttg atgggaccat tggcaggtat tggggattct ctttctcaat tctgtttagc
     3361 tccattgttc tcaaccatcg cagcttcgtt tgctcaagaa ggcttggttg tcggtccaat
     3421 cttgttcttc cttgcgatga atacgatttt aacagcgatt aaattgtcaa ctggtctgta
     3481 tggatacaaa ctaggaacaa ctgtgattga taaactaagc gagcagatgg caacgatttc
     3541 tcgtattgcc aatattatcg gtgtaaccgt aattgctggt ttggcagcga catctgttaa
     3601 gattatggtg ccgattacct ttgctgcagg ggaagttaaa gcagacgcta aacaaagtat
     3661 cgtaagtatt cagggaatgc ttgataaggt tgctccagct cttctaccag ccctatttac
     3721 acttttagtt tactacttga tcaaagaaaa gaaatggaca acatataaac tcgttatttt
     3781 aacagttatc atcggaatta tcggaagctg gcttaagatt atagcttaat ggatacaaca
     3841 ttgttttatg gaatagtgat tgtcttggca gtgagtcccc ttttactgtc aagctttcat
     3901 tctattcgtc agcaaaagtt gcttcgcaaa cagatggagc aacgacaaga gtatttagct
     3961 tctttaacat ttggtgatga agtgttgtta ttgtctggaa ttcatggaaa aatcatttct
     4021 atccaagatg acttggtctc cttgcagatt gcaaaaggtg tggtcatcca tgtagaaaag
     4081 gaaagtgtaa tgggaaagac aaaagaactg ctttttaagt agttcttttt ctggtaatag
     4141 ataatgaaag aagaaagaag acaatttttt gaaagaatcg atggaaacca atgtcgtgat
     4201 tatatcttgt cgcactgttc aaaagactat gagaaagtca agagttccct tgaacgcttg
     4261 atggacaatc gttttatgtt tgatagtcct tgggatatgg agccttgttc aaaaatccat
     4321 caaatccaac cgatggtatg ggatcaagta tttgaagatg atccagaatg ggcttatatg
     4381 ctcaatcgac aagaatatct cttgcagttt atgatagggt atctggtaga aggagataag
     4441 agctatattc aaaagtgcaa gttctttcta tttgattgga ttgagcaggt gagagaattt
     4501 tctcctcaat ccttgatgac tagaaccttg gatacgggta ttcgttcctt tacttggttg
     4561 aaactactct tgctcctctt gaaatttgac ttgctagagg agaaagaact agagaaaatt
     4621 ttggtcagtc tagaaaagca gattgacttt atgaaaagct actatcgcgc caagtacacc
     4681 cttagtaact gggggatttt acaaacaatt ccgatgcttg ctatctatca tttcttttca
     4741 gataagatgg acctagaaga agcttatcat tttgcttcag aggagttgaa acagcaaatt
     4801 gagacacaga ttttaggaga tggaagccag tttgaacagt cgattctcta tcatgtagag
     4861 gtttataaag ccttgctgga tttgtgtctc ttgcttccag acttgcaaga tagttaccaa
     4921 gagttgctgg aaaagatggc gacctatatt caaatgatga caggcttaga tggacggact
     4981 ttggcttttg gtgatagcga ttctacagaa acgacagaaa tgttgagcct gtctgctgtg
     5041 gttttgaaca aggaagacct tcttaacggt ctggatgtta aagtcgattt gcttagcctc
     5101 ttgttcctgg ggcgagaaaa ggtcaagcga ctgcaggaat ttgaaaggag agcttggcag
     5161 cctaagtcca tgatctttga agactctgga catgtctgca ttaaggatga acatcgttat
     5221 ctatttttca aaaatggtcc gctaggaagt gcccatagcc atagtgacga gaatagtttt
     5281 tgcttacagt atcaaggcca acctattttc atagatgctg ggcgttattc ttatcgggag
     5341 atatatgaac gttatctctt aaagagtgct tggagtcatt cgacctgcat tgtagatggg
     5401 aaagctccgg aaagaatcac gggatcctgg gaatatgaat actatcctca ctccctgttt
     5461 tgtcaccata aagaaaggga gggaatgcat tatattgaag gggcttattg gtcagcagaa
     5521 cctgatttgc cttatcttca caagagaaaa atcctcatgt tggtagagga tgtctggctc
     5581 ttggtagatg acatcaggtg tcaaggtcaa catgaggtgt tgactcagtt tatccttgac
     5641 aaggatgtga cctatcaaga tgggaaaatc aatcagttga gactatggag tgaagttgat
     5701 tttgatttgg aagataccat catttctcct aaatacaatg agcttgaaag aagtaacaaa
     5761 ctcaccaagc gccaattctt tgagaatcag atgctggatt ataccatcat tgcgcatgag
     5821 agttttgaaa tcatccgtca ttctgtctac cagacagatg atcgtgaagt ggaaaatgct
     5881 ctggcttttg aagtgaaaaa tgatgaaaca gacaagctga ttctgttatt aagcgaggat
     5941 attggtgtag gtgaaaaatt gtgcctcgtt gacggaacaa aaatgcgtgg aaaatgtcta
     6001 gtatatgata aaataaatga gagaatgatt cgcttgcagt gctagaaata ggcattttga
     6061 atagtgaata tgttataata attattagta ggaggtgttt tagattggag aagaaactga
     6121 ccataaaaga cattgcggaa atggctcaga cctcgaaaac aaccgtgtca ttttacctaa
     6181 acgggaaata tgaaaaaatg tcccaagaga cacgtgaaaa gattgaaaaa gttattcatg
     6241 aaacaaatta caaaccgagc attgttgcgc gtagcttaaa ctccaaacga acaaaattaa
     6301 tcggtgtttt gatcggtgat attaccaaca gtttctcaaa ccaaattgtt aagggaattg
     6361 aggatatcgc cagccagaat ggctaccagg taatgatagg aaatagtaat tacagccaag
     6421 agagtgagga ccggtatatt gaaagcatgc ttctcttggg agtagacggc tttattattc
     6481 agccgacctc taatttccga aaatattctc gtatcatcga tgagaaaaag aagaaaatgg
     6541 tcttttttga tagtcagctc tatgaacacc ggactagctg ggttaaaacc aataactatg
     6601 atgccgttta tgacatgacc cagtcctgta tcgaaaaagg ttatgtgcat tttctcttga
     6661 ttacagcgga tacgagtcgt ttgagtactc ggattgagcg ggcaagtggt tttgtggatg
     6721 ctttaacaga tgctaatatg cgtcacgcca gtctaaccat tgaagataag catacgaatt
     6781 tggaacaaat taaagaattt ttacaaaaag aaatcgatcc cgatgaaaaa actctggtat
     6841 ttatccctaa ctgttgggcc ctacctctag tctttaccgt tatcaaagag ttgaattata
     6901 acttgccgca agttgggttg attggttttg acaatacgga gtggacttgc ttttcttctc
     6961 caagtgtttc gacgctggtt cagccctctt ttgaggaagg acaacaggct acaaagattt
     7021 tgattgacca gattgaaggc cgcaatcaag aagaaaggca acaagtcttg gattgtagtg
     7081 tgaattggaa agagtcgact ttctaaaatg aaggaaaatg acttgcaatc tctgttaaga
     7141 aataaaataa tcccacctag aacaagctag gtgggattat ttgcctatga aatgagaaat
     7201 tatgggagca agctcctaaa tcaactgttt ttgatctact tctttaacta cttgataaaa
     7261 gttatagaag taggccaaac ttgaaatgat ggttacgact aggaatattg aaaatttcca
     7321 ttggacaggg ttggttaaaa gttgtggaaa ggatatgagg agaaagaaga gggctgcgtt
     7381 gaggacaggt atccgttttg attgtatttt ctcaagtcct ttattgagcg caggaagaaa
     7441 gaggagtagg agtagtaaaa ctgtatgaga aacagctcct gaaataaggg cgaagaaaag
     7501 gaaaatactg ataaaaacat gaatgatcag tagtctagct agtgatttca taaggcacct
     7561 cctaatcctg gtctttttta gctcttgcaa tacgaagtga gtcgacaata tgtatcatca
     7621 ctccgaaaaa gaaagctccc agtatagttt taaaaatatg ttttgtattt agaagagaac
     7681 tgataaaatt tggattttca cttgttaggg tatcaatgag tggaattata aaaaatatca
     7741 ctgttccata aatcgaacct gctttcagac caggataacg taactgtctc ttttcttttt
     7801 tcatagggta cctcctaatc ctcatcttga tttttcttag tttttgcaat gcgacgggag
     7861 atgaggaact gtatgctcgc tccgaagaaa atagaaccga gaatgcttga tacaccattt
     7921 cttatagtga gaagagaatg aaaatagtcc tgaccttcac ctatgagtat cctgagaaga
     7981 ggagttataa aaaacatcca tagaccaaag aacaaacctg ctttaagacc tgggtagtgt
     8041 agttgcttgc tttctttctc attcagcata tctggttcaa tgactgtgat gcctgttttt
     8101 ttcatttggt aggtgacata gccagcagcg atgagggcaa tcactaaaat cagaggagga
     8161 tagattagag ccacttcttg agggtattta taggccagaa ggagtggaat aagatttccg
     8221 aaaatcatca gataaaagag gacgataaag acttggttcc caatactatc ggcctcacgc
     8281 cgtttgtatt cgtcaagggg accagaaata ctgtatgtgc gtttgatcag tttttcagtg
     8341 aaggtttctt ttttcatgag tttgctcctt ttttaaaaat cttcctccca aaagagactg
     8401 ttgaggtcag tttggaggct gcgggcgaga ttgagacaga gttccaaggt tggattgtac
     8461 ttgtcgtttt caatcatatt gatagtctgt ctcgagacac cgatatcctt ggcgagttcg
     8521 agctgggaaa tacccaattc cttgcgaaat tctttcacac gattcatctg gtctcctttc
     8581 tgatttatgt cgtatatatt tgactatatt atagtctttt aaacataaag tgtcaagtat
     8641 ttttgacata ttttttgaag aaatagtagt ctccttgtcc tatttgtctg acaagtgcaa
     8701 gctggtcgga tttgtggtaa aatagataag atatgacaaa agaatttcat catgtaacgg
     8761 tcttactcca cgaaacgatt gatatgcttg acgtaaaacc tgacggtatc tacgttgatg
     8821 cgactttggg tggagcaggc catagcgagt atttattaag taaattaagt gaaaaaggcc
     8881 atctctatgc ctttgaccag gatcagaatg ccattgacaa tgcgcaaaaa cgcttggcac
     8941 cttacattga gaagggaatg gtgaccttta tcaaggacaa cttccgtcat ttacaggcac
     9001 gtttgcgcga agctggtgtt caggaaattg atggaatttg ttatgacttg ggagtgtcta
     9061 gtcctcaatt agaccagcgt gagcgtggtt tttcttataa aaaggatgcg ccactggaca
     9121 tgcggatgaa tcaggatgct agtctgacag cctatgaagt ggtgaacaat tatgactatc
     9181 atgacttggt tcgtattttc ttcaagtatg gagaggacaa attctctaaa cagattgcgc
     9241 gtaagattga gcaagcgcgt gaagtgaagc cgattgagac aacgactgag ttagcagaga
     9301 ttatcaagtt ggtcaaacct gccaaggaac tcaagaagaa ggggcatcct gctaagcaga
     9361 ttttccaggc tattcgaatt gaagtcaatg atgaactggg ggcggcagat gagtccatcc
     9421 agcaggctat ggatatgttg gctctggatg gtagaatttc agtgattacc tttcattcct
     9481 tagaagaccg cttgaccaag caattgttca aggaagcttc aacagttgaa gttccaaaag
     9541 gcttgccttt catcccagat gatctcaagc ccaagatgga attggtgtcc cgtaagccaa
     9601 tcttgccaag tgcggaagag ttagaagcca ataaccgctc gcactcagcc aagttgcgcg
     9661 tggccagaaa aattcacaag taagagggaa aaagatggca gaaagaatgg aaaaaacagg
     9721 tcaaatacta cagatgcaac ttaaacggtt ttcgcgtgtg gaaaaagctt tttacttttc
     9781 cattgctgta accactctta ttgtagccat tagtattatt tttatgcaga ccaagctctt
     9841 gcaagtgcag aatgatttga caaaaatcaa tgcgcagata gaggaaaaga agaccgaatt
     9901 ggacgatgcc aagcaagagg tcaatgaact attacgtgca gaacgtttga aagaaattgc
     9961 caattcacac gatttgcaat taaacaatga aaatattcga atagcggagt aagatatgaa
    10021 gtggacaaaa aaagtaatcc gttatgcgac caaaaatcgg aaatcgccgg ctgaaaacag
    10081 acgcagagtt ggaaaaagtc tgagtttatt atctgtcttt gtttttgccg tttttttagt
    10141 caattttgcg gtcattattg ggacgggcac tcgctttgga acagatttag cgaaggaagc
    10201 taagaaggtt catcaaacca cccgtacagt tcctgccaaa cgtgggacta tttatgaccg
    10261 aaatggagtc ccgattgctg aggatgcaac ctcctataat gtctatgcgg tcattgatga
    10321 gaactataag tcagcaacgg gtaagattct ttacgtagaa aaaacacaat ttaacaaggt
    10381 tgcagaggtc tttcataagt atctggacat ggaagaatcc tatgtaagag agcaactctc
    10441 gcaacctaat ctcaagcaag tttcctttgg ttcgaagggc aatgggatta cctatgccaa
    10501 tatgatgtct atcaaaaaag agttggaaac tgcagaggtc aaggggattg attttacaac
    10561 cagtcccaat cgtagttacc caaacggaca atttgcttct agttttatcg gactagctca
    10621 gctccatgaa aatgaagatg gaagcaagag tttgctggga acctctggaa tggagagttc
    10681 cttgaacagt attcttgcag ggacagacgg tattattacc tatgaaaaag accgtgtagg
    10741 aaatatcgta ccaggtacag aactggtatc gcaacaaact gtggatggca aggatgttta
    10801 tacaacattg tctagtccgc tacaatcttt catggaaact cagatggatg cctttctaga
    10861 aaaggtaaaa ggtaagtata tgaccgcgac cttggtcagt gcaaagaccg gtgaaatcct
    10921 cgctaccacc caacgaccta cctttaatgc agatactaaa gaaggaatca ctgaggactt
    10981 tgtttggcgt gatattcttt atcaaagtaa ctatgaacca ggatcagcca tgaaggttat
    11041 gacgttagct tcttctattg ataataatac cttcccaagt ggagaatact tcaatagcag
    11101 tgaatttaaa atagcggatg cgacgactcg agattgggat gttaatgagg gtttgactac
    11161 tggtgggatg atgactttct tacaaggttt cgctcactcc agtaatgttg gaatgagtct
    11221 acttgaacaa aaaatgggag atgctacttg gttggattat ctaaaacgct ttaaatttgg
    11281 ggttccaact cgctttggct tgacagatga atacgctggt caacttccag ctgataatat
    11341 tgttagtatt gctcaaagct catttgggca aggaatttca gtgacacaaa cacaaatgct
    11401 tcgtgccttt acagctattg ctaatgatgg agttatgctg gagccaaaat ttataagtgc
    11461 tatttatgat actaacaatc agtctgtacg aaagtctcaa aaagagattg taggaaaacc
    11521 tgtatctgaa gatacagcaa gcttgactcg tactaacatg atattagttg ggacggaccc
    11581 tctatatgga actatgtata atcactacac aggaaagcca attataacag ttcctggaca
    11641 aaatgtagca gttaaatccg gtacggctca aatcgctgat gagaaaaatg gaggatactt
    11701 ggttggttct accaattata ttttctcagc tgtgactatg aatcctgctg aaaatcctga
    11761 ttttatcttg tatgtaacgg ttcaacagcc tgagcattat tcaggtatcc agttgggaga
    11821 atttgccacc ccaatcttgg agcgggcttc agctatgaaa gaatctctca atcttcaatc
    11881 tccagctaag aatttagatc aagtgacgac agaatcttcg tatgcaatgc ctagcatcaa
    11941 ggatatttca cctggtgatt tggcggaagc cttacgtcga aatattgtgc aaccaatcgt
    12001 tgttggtact ggaacaaaga ttaaagagac ttctgtagaa gaaggaaaaa atcttgcacc
    12061 aaaccaacaa gttctccttt tatcggataa ggtagaagaa attccagata tgtatggttg
    12121 gacaaaagca accgcagaag ctttttctaa gtggttaaat atagaacttg tatttgaagg
    12181 ttcaggttct actgtgcaga agcaagatgt tcgtgctaac acagctatca aggacattaa
    12241 aaaaattaca ttaactttag gagactaata tgtttatttc catcagtgct ggaattgtga
    12301 catttttact aactttggta ggaattccag cctttatcca attttataga aaggcgcaaa
    12361 ttacaggcca gcagatgcat gaggatgtca aacagcatca ggcaaaagct gggactccta
    12421 caatgggagg tttggttttc ttaattgctt ctgttttagt tgctttcttt ttcgccctat
    12481 ttagtaatca actcagcaat aatgttggta tgattttatt tatcttggtt ctctatggtt
    12541 taatcggatt tttagatgac ttcctcaagg tcttccgtaa aatcaatgag ggccttaatc
    12601 ccaaacagaa attggctctt cagcttctag gtggtgtcat tttctacctt ttctatgagc
    12661 gtggtggcga tatgctttct gtctttggct accaagtgca tctagggatt ttctatattg
    12721 tcttcgctct tttctggcta gtcggttttt caaacgcagt aaacttgaca gacggtattg
    12781 acggtttagc tagcatttcc gttgtgatta gtttgtctgc ctatggagtt attgcctatg
    12841 tgcaaggtca gatggatatc cttctagtga ttcttgccat gattggtggt ttgcttggtt
    12901 tctttgtctt taaccataag cctgctaagg tctttatggg agatgtggga agtttggctc
    12961 tcggtggaat gctggcagct atttcaatgg ctctccacca agaatggact ctcttgatta
    13021 tcggaattat ttatgtcttt gaaacaactt cggtcatgat gcaagtcggc tatttcaaaa
    13081 tgactggtgg aaaacgtatt ttccgtatga cgcctgtgca tcaccatttt gaacttggag
    13141 gattgtctgg taaaggaaat ccttggagcg agtggaaggt tgacttcttc ttttggggag
    13201 tggggcttct agcaagtctc ctgaccctag caattttgta tttgatgtaa gaatggcacc
    13261 ctgatgtttc agggtgtttt tgtgtttaaa tacacaatga aaatcaaaga acaaactaga
    13321 aagctaactt taggctgctc aaaacatagt agtttgaaac tagaatagta cacatctact
    13381 tctaaaatat tgttagaaat cgatttgact gtcctgatcg atttgtcctg ttcttatttc
    13441 attttaatat acagttttga gatgggtgat agaactgacg aagtcagctc aaaacacggt
    13501 tttgaggttg tagataagga gaagctgatg tggtttgaag aggttttcga agagtgtaaa
    13561 aaaatattgg tcagttaaag tcaaaactct tgaccttttc tgaccaatgt agtatattat
    13621 gaacgtaagg taaatgaaag ccttactaga acacttattt aaagtaaaat agaaagaggt
    13681 gggtctatgt ttcatctaga aatcttcaga agtaaagatg gtctactcct gcttgaaaaa
    13741 gaaaaaccag aaatagtacg tagggtagcg gtttagctag tctaaatttt ttaaaacaat
    13801 ggtcaaagat agtcaatatc agtaatcata actaagtaaa caaaaagagg taaagaatat
    13861 gaataacaac tttaataatt ttaataacat ggatgattta tttaaccaat tgatgggtgg
    13921 tatgcgagga tatagttctg aaaatcgccg ttacttaatt aatggacgcg aagtcacacc
    13981 tgaggaattt gctcactatc gtgcgactgg tcaattacca ggaaatgcag aaactgatgt
    14041 gcaaatgcca caacaggcat caggtatgaa acaagacggt gtccttgcaa aactaggtcg
    14101 aaacttgaca gcagaagcgc gtgagggcaa gttggatcct gttatcggac gaaacaagga
    14161 aattcaagaa acatctgaaa tcctctcacg ccgcaccaag aacaatcctg ttttggtcgg
    14221 agatgcaggt gttggtaaga cagcagttgt cgaaggtcta gcgcaagcca ttgtgaacgg
    14281 agatgttcct gctgctatca agaacaagga aattatttct attgatatct caggtcttga
    14341 ggctggtact caataccgtg gtagctttga agaaaatgtc caaaacttag tcaatgaagt
    14401 gaaagaagca gggaatatta tcctcttctt tgatgaaatt caccaaattc ttggtgctgg
    14461 tagcactggt ggagacagtg gttctaaagg acttgcggat attctcaagc cagctctctc
    14521 tcgtggagaa ttgacagtga ttggggcaac aactcaagac gaataccgta acaccatctt
    14581 gaagaatgct gctcttgctc gtcgtttcaa cgaagtgaag gtcaatgctc cttcagcaga
    14641 gaatactttt aaaattcttc aaggcattcg tgacctctat caacaacacc acaatgtcat
    14701 cttgccagac gaagtcttga aagcagcggt ggattattct gttcaataca ttcctcaacg
    14761 tagcttgcca gataaggcta ttgaccttgt cgatgtaacg gctgctcact tggcggctca
    14821 acatccagta acagatgtgc atgctgttga acgagaaatc gaaacggaaa aagacaagca
    14881 agaaaaagca gttgaagcag aagattttga agcagctcta aactataaaa cacgcattgc
    14941 agaattggaa aagaaaatcg aaaaccacac agaagatatg aaagtgactg caagtgtcaa
    15001 cgatgtggct gaatccgtgg aacgaatgac aggtatccca gtatcgcaaa tgggagcttc
    15061 agatatcgaa cgtttgaaag atatggctca tcgcttgcaa gacaaggtga ttggtcaaga
    15121 taaggccgta gaagctgtag ctcgtgctat ccgtcgtaac cgtgctggtt ttgatgaagg
    15181 aaatcgccca atcggcagct tcctctttgt aggatctact ggggttggta agacggagct
    15241 tgctaagcaa ttggcactcg atatgtttgg aacccaggat gcgattatcc gtttggatat
    15301 gtctgaatac agtgaccgca cagctgtttc taagctaatt ggtacaacag caggctatgt
    15361 gggttatgat gacaatagca ataccttaac agaacgtgtt cgtcgcaatc catactctat
    15421 cattctcttg gatgaaattg aaaaggctga tcctcaagtt attacccttc tcctccaagt
    15481 tctagatgat ggtcgtttga cagatggtca aggaaataca gtaaacttca agaacactgt
    15541 cattattgcg acctcaaatg ctggatttgg ctatgaagcc aacttgacag aagatgcgga
    15601 taaaccagaa ttgatggacc gtttgaaacc tttcttccgt ccagaactcc tcaaccgctt
    15661 taatgcagtc atcgagttct cacacttgac taaggaagac ctttctaaga ttgtagattt
    15721 gatgttggct gaagttaacc aaaccttggc taagaaagac attgacttgg tagtcagtca
    15781 agcggctaaa gattatatca cagaagaagg ttacgacgaa gtcatggggg ttcgtcctct
    15841 ccgtcgcgtg gttgaacaag aaattcgtga taaggtgaca gacttccact tggatcattt
    15901 agatgctaaa catctggaag cagatatgga agatggcgtt ttggttattc gtgagaaagt
    15961 ctaagacaga attttgagga taaaaaagaa ggagccagct gaaaaaaact ggttcctttt
    16021 gaggtatgac gggcatgtcg tatagtagaa gtgtattatt ctagtttcaa tttactatag
    16081 tagctcagaa gtcggtactt aaacgtgcta tatcaaaacc agtccttgaa aaacgtggac
    16141 tggtttcgtg tttggattat taccttgaac gacatgcgtt aaaagttagt tgaacagccg
    16201 tatgccgaac ggcacgtacg gtggtgtgag aggggctaga gattatcccc tactcgattt
    16261 taaatcacat gacgttcaaa ggcatcatct gaaatccctt gttccaagat gagttttgcc
    16321 cattctttag cagagaagag gctgtggtcc ttgtagtttc cgcaagattc gatggttgtc
    16381 cctgggacat cttcccaagt agtagtttca gcgatttcct tgagcgaatc cttgataaca
    16441 gctgcgattt tagcactggt gtgacgtccc cacataatca tgtggaagcc tgtgcggcaa
    16501 ccaaatggtg aacagtcaat catgccgtca atgcgggtac ggatgagttt ggctaagagg
    16561 tgctcgatag tgtgaaggcc ggcagtaggg atagagtctt cgtttggttg caccaagcga
    16621 atatcataat tggagatgat gtctcctttt ggtcctgttt cttccccaat caagcgaaca
    16681 tagggtgctt tgacaatggt gtggtcaagt tcaaaacttt cgacaataac ttcttttgac
    16741 atggtaaatc ctttcagttt tcttctctca ttatatcata aaggttgctc ctgagacaga
    16801 gagaaaacct ctccgaggct ggagaggttg aaatctttac ttacgatata agcggtcgta
    16861 ttggtagtat gggtcaaagg ttacgttgat acccagttta cgaaggacat tcttgtcttc
    16921 atcagtcaag atgatggttg agtgggcttc gcttcctttg aggttgccga gttcttccat
    16981 agcgcgggca gcatcaggat tttctgtagc tgtgatagca agtgcaatca ggatttcatt
    17041 tgaatgaagg cgtggattgc ggctaccgag atgatcgatt ttaagacctt ggattggctt
    17101 aacaacttca ggctcgatta gttttacttc tttagcgatg tcagctgatt ttttgatggc
    17161 attgatcaag gcagcggctg tagggccaaa gagttctgag ttcttaccag tgatgatttc
    17221 cccatttggc aattcaaagg ctagggctgg tccaccagtt tcttctgctt tttggcgcgc
    17281 aacgacagca accttacggt ctgcaggtgt gataccgagg tcgttcatga gcaactcaat
    17341 tttcttgacg gcagcttcgc caactttttc agctttgaag tcaagaactg tttgatagta
    17401 acggcggatg atttcttgtt tagaagcttc gacagcagcc tcgtcatctg taatagcgaa
    17461 accaaccatg ttgacaccca tatctgtcgg tgaagcgtat ggtgattttc cgagaatacg
    17521 ttccaacatg cgcttgagca ctgggaagat ttcgatatca cggttgtagt tgacagtggt
    17581 ttctccatag gtttgaagat ggaaggggtc aatcatgttg acatcatcaa ggtcagctgt
    17641 ggcagcttca taagccaagt taactggatg atgaagggga agattccaaa cagggaaggt
    17701 ttcaaattta gcgtagccag atttgatgcc attgatttgg tcgtggtaca tattggacat
    17761 acacgttgcc aattttccag aaccgggtcc aggagcggtt acgacaatca agttgcgact
    17821 ggttttgatg tagtcgtttt tgcccatgcc ttctggggaa atgatgtgat ccatatccgt
    17881 cggatatcct ttgattggat aatgaagata agaatcaatt ccgtttttct caagttggtt
    17941 gcggaaggca tctgcagcgg gttggccagc gtattgtgta atgacaacgg aaccaacaaa
    18001 aatccctaat tcattgaatt tgtcaatcaa acgaagaact tcttggtcat aagaaatgcc
    18061 caagtcgcca cgtgctttgg aatgttcaat gttgctagca ttaatggcaa tcacaacctc
    18121 aacctgctct ttcaattctt gcaagagctt gattttgttg tcaggttcat aaccaggaag
    18181 gacacgagca gcgtggaaat cttctaacat tttgccacca aactctaggt aaagcttgcc
    18241 gtcaaattgg ttaatgcgct ctaagatgtg gtcgcgttgt aaattcaaat actgttcaga
    18301 actaaaagct tgttttttca tttttttacc tctggactct attataataa aaaattggaa
    18361 gttaggaaac tacggagcta aaaaataaat taaaaagatt aagcaaacgc ttgcacaaaa
    18421 ttttaaaaag tgctatcata tactatagat tattaaaata atgaggtaaa cagatgcaag
    18481 aaaaatggtg gcacaatgcc gtagtctatc aagtctatcc aaagagtttt atggatagta
    18541 atggagatgg agttggtgat ttgccaggta ttaccagtaa gttggactat ctagccaagc
    18601 taggaatcac agcaatttgg ctttctcccg tttatgacag ccctatggat gataatggct
    18661 atgatattgc tgattatcaa gcgattgcgg ctatttttgg aaccatggag gacatggatc
    18721 agctgattgc agaagctaag aagcgtgaca ttcgtatcat catggacttg gtggttaatc
    18781 atacctcaga tgaacatgct tggtttgtcg aagcctgtga aaatactgac agccctgagc
    18841 gagactacta tatctggcgc gatgaaccca atgacctaga ttctatcttt agtgggtctg
    18901 cttgggaata cgatgaaaag tcaggtcaat actatctcca ctttttcagc aagaaacagc
    18961 cggatctcaa ctgggaaaat gaaaaacttc gccagaaaat ttatgagatg atgaacttct
    19021 ggattgataa aggtattggt ggtttccgta tggatgttat tgacatgatt ggcaaaattc
    19081 ctgacgagaa ggtagtcaat aatggtccta tgctccatcc ctatctcaag gaaatgaatc
    19141 aggcgacctt tggagataag gatctcttga cagtagggga gacttgggga gcaacgccag
    19201 agattgccaa gctttactct gatccaaagg ggcaagaatt gtctatggtc ttccagtttg
    19261 aacatatcgg tcttcagtat caggaaggtc agcctaaatg gcactatcaa aaagagctga
    19321 atatcgctaa gttaaaagaa atcttcaaca aatggcagac agagttagga gttgaggacg
    19381 gttggaattc cctcttctgg aacaatcatg acctccctcg tatcgtctca atctggggaa
    19441 atgaccaaga ataccgcgaa aaatctgcca aagcctttgc aatcttgctt catcttatga
    19501 gaggaactcc ttatatctac caaggtgagg agattgggat gaccaactat ccgtttgaaa
    19561 cactggatca agtagaagat attgaatctc tcaactatgc gcgtgaggct cttgaaaaag
    19621 gtgttccgat tgaagaaatc atggacagta tccgtgttat tggacgtgac aatgcccgta
    19681 cccctatgca atgggacgag agcaaaaacg ctggtttctc aacagatcaa ccttggttgg
    19741 cagttaatcc aaattacgag atgatcaacg tccaagaagc gctggcaaat ccagattcta
    19801 ttttctatac ctatcagaaa ctggtccaaa ttcgcaagga gaatagttgg ctaattcgag
    19861 ctgactttga attgcttgat acggctgata aggtctttgc ttatatacgt aaggatggcg
    19921 accgtcgctt cctagttgtg gctaacttgt ccaatgaaga gcaagacttg acagtagaag
    19981 gaaaagtcaa atctgtcttg attgaaaaca ccctagctca agaagtcttt gaaaaacaaa
    20041 tcttagttcc atgggatgct ttctgtgtgg aattactata aatatttttt gcagaaaaat
    20101 ttaaaattga aatcatataa aaacaaggga ggactgtata aaaggcggaa atcctttgtt
    20161 ttttataacc aaggtttata aactttcatt ctcgaaattc aattaacttt acaaattccc
    20221 actattaagg agaaagaaga cgaacataaa gaagcgtatc cttagtgcag gcctgacttt
    20281 tgcggctgcc ttgcttttag ctgcttgcgg acaatcaggt tcagatacaa aaacttactc
    20341 atcaaccttt agtggaaatc caactacatt taactatcta ttagactatt acgctgataa
    20401 tatagtcaat tgaaacaaga gaaagacaaa agagcctcgt aaaaggtatt gcaacttggt
    20461 aatacctttt tgaggtgctt tttgatatga gcccatgttt tctcaatagg attgtactca
    20521 ggtgagtagg gaggaagagg taaaagttta tgcccaaact cttcgcataa aagttctagc
    20581 ttccccattc tatggaatct tgcattatcc ataataataa ccgatggtgt ggttaatgtt
    20641 ggtaagaaaa acttctgaaa ccaagcttca aaaaagtcgc tcgtcatcgt ctcttcgtaa
    20701 gtcattggaa cgattaactc accatttgtt agacctgcaa ccaaagaaat cctctgatat
    20761 cttcttccag atactttgcc tcttcttaac tgacctttta atgagcgacc atattctcga
    20821 taaaaataag tatcgaatcc tgtttcatca atctaaacag gtgctaggtg ctttaaacta
    20881 ttaaaattct taagaaataa ggctactttt tctgggtctt gttcataatt agattgaaac
    20941 tagaatagta cacctctgct tctaaaacat tgttagaaat cgatttgact gtcctgatcg
    21001 atttgtcatg ttcttatttc attttactat atttttgttt cgcgggaagt ctactaagat
    21061 acttaaagat gcagatagta aaaaaaaatg tagacattac cgtaaaaaag tgatataatc
    21121 gtatgatgtt caaggtatag gtgttaatca tgagtagacg ttttaaaaaa tcacgttcac
    21181 agaaagtgaa gcgaagtgtt aatatcgttt tgctgactat ttatttattg ttagtttatt
    21241 ttttattgtt cttaatcttt aagtacaata tccttgcttt tagatatctt aacctagtgg
    21301 taactgcgtt agtcctacta gttgccttgg tagggctact cttgattatc tataaaaaag
    21361 ctgaaaagtt tactattttt ctgttggtgt tctctatcct tgtcagctct gtgtcgctct
    21421 ttgcagtaca gcagtttgtg ggactgacca atcgtttaaa tgcgacttct aattactcag
    21481 aatattcgat cagtgttgct gttttagcag atagtgagat tgagaatgtt acgcaactga
    21541 tgagtgtgac agcaccgact gggactgata atgaaaacat tcaaaaacta ctagctgata
    21601 tcaaatcaag tcagaatacc gatttgacgg tcaatcagag ttcgtcttac ttggcagctt
    21661 ataagagttt gattgcagga gagactaagg ccattgtctt aaatagtgtc tttgaaaata
    21721 tcatcgaatc ggagcatcca gattacgcat cgaagataaa aaagatttat accaagggat
    21781 tcactaaaaa agtagaagct cctaagacgt ctaaggatca gtctttcaat atctatgtta
    21841 gtggaattga tacttatggt ccgattagtt cggtgtcgcg ttcagatgtc aatatcctga
    21901 tgactgtcaa tcgagatacc aagaaaattc tcttgaccac aacgccacgt gatgcttatg
    21961 taccaatcgc agatggtggg aataatcaaa aagataaatt gacccatgcg ggcatctatg
    22021 gagttgattc gtccatccac actttagaaa atctctatgg agtggatatc aattactatg
    22081 tgcgattgaa cttcacttct ttcttgaaat tgatcgattt gttgggtggg gtagatgttt
    22141 ataatgacca agattttaca tctctacacg ggaagttcca tttcccagtt ggaaatgtcc
    22201 acttagattc tgagcaggct ctgggatttg ttcgtgagcg ctattcccta gcggatggtg
    22261 atcatgaccg cgggcgcaat caacaaaagg tgattgcggc catccttcaa aaattaactt
    22321 cgagcgaagc gctgaaaaat tatagtagga tcattgatag cttgcaagat tctatccaaa
    22381 caaacatgcc acttgagacc atgataaact tggtcaatgc tcagttagaa agtggtggaa
    22441 cgtacaaagt gaattcgcaa gacttgaagg gtatgggacg gacggatctt ccttcctatg
    22501 cgatgccaga tagtaacctc tatatgatgg aaattaacga cagtagcctt gcatctgtca
    22561 aaactgctat tcaggatatg ttggagggca gatgaaatga ttgatattca ttcgcacatc
    22621 gtctttgatg tagatgatgg tcccaagtca agagaggaaa gcaaggctct cttggcagaa
    22681 tcctacaggc agggggtgcg aaccattgtc tctacctctc accgtcgcaa gggcatgttt
    22741 gaaactccgg aagagaagat agcagaaaac tttcttcagg ttcgggaaat agctaaggaa
    22801 gtggcgagtg acttggtcat tgcttacggg gctgaaattt actacacatc agatgttttg
    22861 gataagctgg aaaaaaatcg gattccgacc ctcaataata gtcgttatgc cttgatagag
    22921 tttagtatga acacccctta tcgcgatatt catagtgcct tgagtaaaat attgatgttg
    22981 ggaattactc cagtcattgc ccacattgag cgctatgatg cacttgaaaa taatgaaaaa
    23041 cgcgttcgag agctgatcaa tatgggctgt tacacgcaag taaatagttc acatgtcctc
    23101 aaatccaaac tttttggaga acgttataaa ttcatgaaaa aaagagctca gtattttttg
    23161 gagcgtgact tggttcatat cattgcaagt gatatgcata atgtggacag cagacctccc
    23221 catatggcag aagcatatga ccttgtttcc caaaaatacg gagaagcgaa ggctcaggaa
    23281 ctttttatag ataatcctcg aaaaattgta atggatcaac taatttagga gaaatgatga
    23341 aagaacaaaa cacgatagaa atcgatgtat ttcaattact taaaaccttg tggaaacaca
    23401 agctaataat tttattagtg gcacttgtga caggggcggg agcttttgca tatagcactt
    23461 ttattgttaa gccagaatat acaagcacca cgcgtattta cgtagtcaac cgtaatcaag
    23521 gagataagcc gggactgacg aatcaggact tgcaggcagg aacttatctg gtaaaagact
    23581 accgcgaaat tatcctttcg caagatgtat tggaaaaggt agcgacaaat ttgaaattgg
    23641 atattccagc aaaaacgtta actagcaaag tgcaagtgac tgtaccagcc gacactcgta
    23701 tcgtctcaat ctctgtcaag gataaacaac cagaggaagc cagtcgcatt gctaattctc
    23761 tacgagaagt tgctgcagaa aagatcatcg ctgtaacgcg agtatctgat gtaacgacgc
    23821 ttgaagaagc gcgaccagct atgactccct cttctccaaa tgttcgacgc aacaccttag
    23881 ttggttttct tggaggagcc gccgtaacag taattactgt tcttttgatt gagttgctcg
    23941 atacccgtgt aaaacgtcct gaagatgttg aagatgtact gcaaatgcca cttctaggag
    24001 tcgttccaga ttttgataaa atgaaatagg aggaagttat gccaacgtta gaaatctcac
    24061 aggcgaaatt agaacttgtg aaaaaggcag aggaatatta taatgctttg tgcacgaacc
    24121 tacagttaag tggagatgat ttgaaagtat tttctatcac ttctgtgaaa gcaggagaag
    24181 gaaaaacaac gacttccacc aatatcgctt gggcttttgc gcgtgcaggt tacaaaacgc
    24241 ttctgattga tgcagacatg cgtaactccg ttatgtcagg tgtctttaaa tcaagggaaa
    24301 ggattactgg actaacagaa tttctatcag ggacaacaga cctgtcacag gggctttgcg
    24361 ataccaatat tgagaatctc tttgtgattc aggctggctc tgtgtcacca aatccgacag
    24421 cccttcttca aagtaagaat ttcagtacaa tgcttgaaac cttgcgtaaa tattttgact
    24481 atatcgtcgt agacactccc cctgtcggtg tcgtgattga tgcggctatc attatgcaga
    24541 aatgtgatgc ttctatttta gtgacgaagg caggtgaaac aaaacgacgg gatcttcaaa
    24601 aagcgaaaga acagttggaa caaactggga agtcgtgttt aggagttgtg ttgaataaac
    24661 tcgatacttc agtagagaaa tacggttctt atgggagtta tgggaattac aggaaacaga
    24721 aaaaataggt tgagggatag aaatgagtga aaaactagca aagccttcag tagccatagt
    24781 ccagagtttt cttgttattt tattgactta tctacttagc gctgtgagag aaacagagat
    24841 tgtttcaaca acagctattg tactttatat cctccactat tttgtctttt atatcagtga
    24901 ttatggacgg aatttcttta aaaggggata tttgattgaa cttgtccaga cattgaaata
    24961 tatcctattc tttgcgctag cgattagtat ttctaatttt ttcttagaag atcgatttag
    25021 tatttccaga agaggcatga tttacttcct cttattacat gttttcttag tctatgtgct
    25081 aaacccattt atcaagtggt attggaagcg ggcttatccc aactttaaag gaagtaagaa
    25141 gattctccta cttacagcaa cttctcgtgt tgaaaaggta ctggatagat taatagaatc
    25201 aaatgatgtt gttggggagt tggtagccgt cagtgtttta gataaaccag attttcagca
    25261 tgatgattta aaggttgtag cagaggggga gatagtaaat tttgcgactc atgaggtggt
    25321 cgatgaagtc tttatcaatc ttccaagtga aaaatacaat attggagagc ttgtctctca
    25381 gtttgaaacg atgggaattg atgtaacagt caatctaaat gctttcgatt gggcacgtaa
    25441 caagcaaatt tgtgagatgg caggactaaa tgttgtgact ttttctacaa cattttataa
    25501 gactagccat gtgattgcta agcggattat tgatattgtc ggttccctgg taggtttgat
    25561 attatgtggt ctagtcagta ttgtgctggt tcctttgatt cgaaaggatg ggggttctgc
    25621 tttttttgct cagacgcgta taggaaaaaa tggccgccat tttacttttt ataagtttcg
    25681 ctctatgtgt gtggatgctg aggagaaaaa aagagaactc atggaacaaa ataccatgca
    25741 gggtggaatg tttaaggtgg acgatgatcc tcgtatcacg aaaattggtc attttatacg
    25801 gaagacgagc ttggacgagc taccacagtt ttataatgtt ctaaagggag atatgagttt
    25861 ggtaggtaca cgaccaccaa cagtggacga gtatgagcac tataccccag aacaaaaacg
    25921 tcgcctaagt tttaaacctg gcataacagg tttatggcag gtcagcggac gaagtgaaat
    25981 caaaaatttc gatgaagttg tcaaattaga tgtggcctat attgatggtt ggacaatctg
    26041 gaaagatatt gaaattttat tgaagacagt taaggttgta ttgatgaagg atggagcgaa
    26101 atagttcata tgaatgagag aattcaaata ttaggaatta ctatagatcc attaacgatg
    26161 aaagaaacag tggatgctgt tgaacagtat gttttaaaga agcacccttt gcacttgatg
    26221 ggagttaacg cggataaaat taatcagtgc tatgaagatg agaaaatcaa aaaaatcgtt
    26281 aatgaatcag gaataattaa tgccgacggt gcttcagtag ttttagcgag taagttttta
    26341 ggaacaccag ttcctgagcg agttgctgga atagacttga tgaaacattt actagagttg
    26401 tctaatgaaa aaggatactc ggtctacttt tttggagcaa aagaagacgt tttacaagat
    26461 atgttaaaaa tttttgaaga aagatatcca gctctaaatg ttgttggcta tagaaatgga
    26521 tatttttcgc ctgaagatga aaaacatatt caggaagata ttaaagagaa aaaaccagat
    26581 tttgtgtttg taggaattac ttctcctaag aaagaatata ttatccaatc attcatggat
    26641 aatggaatta atgctgtgtt tatgggggtt ggtggaagtt ttgatgtact atcagggcat
    26701 atcaaacgag ctccattatg gatgcaaaat gctcacctag agtggttgtt tcgtgtggca
    26761 aatgagccta aacgtctctt taagcgttat tttgtaggga atgtttcatt tataagaaaa
    26821 gttttaagag cgaaaagggg atataaactt tgaaccaaac agaaatagtt aaattgattc
    26881 agaaagttga attggatgct ataaaagagt ttcaaaaaat ttgtaaagag aacaatatag
    26941 atttcttcct tcgtgggggg agtgtacttg gggcagtcaa atatgatggc tttattccat
    27001 gggatgatga catggatatt gctgtgcctc gtgaaggcta cgataaactt ccaggtatct
    27061 ttaaggatag aattatcgca ggcaaatatc aggttcttgc ttatcaatat tgcgatactt
    27121 tacattgcta ctttcctcgc ttattccttt tagaagatga aagaaaacgt ttgggattgc
    27181 cacgaaatac caatttaggt ttgcatttga ttgatatcat tcctttggat ggtgccccaa
    27241 atcattcatt tttaagaaag ctttacttcg gtaaagtata ctggtatcgt tttttagcaa
    27301 gtttaggaac tacctatgtt ggagaccatg tggatatgca ttccgctaag caaaaactaa
    27361 tcattggttt ctttaaaaag ctaggatttg caaaactatt ccctcaaaat tatgtgtaca
    27421 gacgcttgga taatctctat aaaaagtatg attggaaaaa gcagaagtat gctgggacaa
    27481 ttaatgcatc tctgtttgcc aaagaagtca tgccagtaga gatttgggga gaaggagtag
    27541 agaagccttt tgaggatgcc ttctttaaag ttcccacgga gtatgaccgc tatctgaaaa
    27601 gactttacgg agaaaactat cttcacgaag agcctagtga tgatgaaaag aaatcgcatt
    27661 taggaggaca ataatttgtt ttgttatatt attttgcatt acaaagtctt agaggaaact
    27721 atttcttgtg ttaaatcaat aaaagaaggc aattccaata caaagcagat cgttattatt
    27781 gataattttt ctaataacgg tacgggtgaa aaactacaag agctgtatga gtcagattca
    27841 gagattgatg tcttgattaa ccatgaaaat gctggtttcg ctcgaggtaa taatgtagca
    27901 tatcagtttg ctaaggaaaa gtacaaacct gattttatgg ttatcatgaa taatgatatt
    27961 gagatagaaa cagaagagtt tgaaaaaatc gtgacagata tctatcggaa ggaaaaattc
    28021 catttgttag gaccagatat cttttcgacg acgtatcagc ttcaccaaaa cccaaaacgg
    28081 ttgacgcatt atacttatga agaggttaag gctctcaatg aaaaatttaa gaaagggagc
    28141 caagttagtc tagcattaaa aattaaatgt tggttgaagt ctagtaaagt tcttcggaca
    28201 gcaatctatc aaaataggcg taaaaagaaa tcagtagact atagaaaaca ggtagaaaac
    28261 ccaattcttc atggttcgtt tattgtatat tctagagatt ttattgagaa agaggagtat
    28321 gcttttaatc ccaatacctt cttctattat gaaacagaga tattagatta tgaagctgag
    28381 ttaaaaggat ataagagaat ttatacaccg aagattaagg tcttgcacca tcaaaatgtt
    28441 gcaaccaatc aagtctatac aaacttagta gaaaaaacct tgttttcaaa caaatgcaac
    28501 tttgaatcca ctagttattt tttgaagttg atgaaagaaa acgagggtgt gtaaatgact
    28561 tatttatttt tactctgcct gaccttattc ttattaactt tcttctattt ttttgctttc
    28621 aatcaagatt tgatagctcc gccagttgtc atgtctgtta tgtttctcat tagttctgta
    28681 tttgccctta ttaatgtgca aaactggaat attgagtata gtggtttagc ttatcttttg
    28741 attattagtg gcattattgt tttttcaatg cctctcttgg ctcttaattc gcctagtcta
    28801 aataccaaga ttaaagtgac ggatcggctc attgatatcc aattctggaa aatagctctt
    28861 actattatag ttgacctcgt tattctatat ctttatagga gagagattca taatcttgca
    28921 cttagccatg gttatacggg ttcaaatttt cagtggttct ttagaaatgc taccagttat
    28981 gaaggtgagc taacagtgcg aacttcgatt cgggtcctca ttcgtatcat tgacgtatct
    29041 gcttatattt ttggatatac ttttattaat aatttcttca tttatagtca taaacgctct
    29101 aaagatttac tgctcttagt tccattcttg atttttattt ctaaaacctt attatctggg
    29161 ggtagattgg atattataaa aattttaatt gcgtatgttg taatggccta tattcagcaa
    29221 aaacgaaaag ttggctggga taaggtcatc tcccataaat atatgagact tggttttgta
    29281 ggcttgatag ctgggattcc taccttttac tattctttat tcttatctgg acgttctacg
    29341 actagaactg tatttgaaag tatttcaacc tatttaggag gttcgattca gcattttaat
    29401 cagtatattc aaaatcctat tggagtagct gaggtttttg gcgatgagtc atttgtagct
    29461 attatgaata ttttgggtaa tcttggcttt gtcaattaca atagtaccgt tcacttagaa
    29521 tttcggcagt tagggattac tatgggtaac gtttatactt tctttagaag accctggcat
    29581 gactttgggt tagtcggtat gtatatcttt tcctttgttg tcggtgtgtt ttttgctatt
    29641 ttttatttga aattaagaaa gagccgtgct ggttttaaat tggatattca tacaattatt
    29701 tactcttatt tcttttattg gattttttta tcgtccattg agcaatactc gtttacaaca
    29761 atcagtttgt ttacacttgt atttatagtc ttggtttacc taatggcttt cttctattgg
    29821 aatttggatt tccacagagg aaaactagta attaaactct ctgacacaag tattaaatcg
    29881 gaaaactgaa aacaataaaa atagagagga tagttgatga atagcaaaat taaaaatata
    29941 ctaactaatt tctcttatgt catttcttca aatcttttga cagtcttgac ctcttccttg
    30001 gttgtcttaa ttttccccaa attaatgggg gtaacagagt acagttactg gcaactttat
    30061 attttttatc tgacctatat cggttttttc cacttgggtt ggattgatgg gatttatctt
    30121 aaatatggtg gcttagaata taataattta gatagaaaac agttttattc tcagatgatt
    30181 ctattttcta gcttcttaat gattatctcc ttgctattgt ttggtttaaa tgtattagct
    30241 gtaacagatt cgaatgcacg atatatttat aatatgacta ttataagtat gataatcaca
    30301 aatttaagaa cgctctacgt gtatgttttg cagatgacaa accgcttgaa ggatagttcc
    30361 atcattctac tcagtgatcg cgttttatat gtgctccttt tattcctgtt tattgtattt
    30421 ggttggcatg aatacaaggt tatgattttg gcagatattc taggtcgatc attttctctc
    30481 atactttcct tctggatttg taaagatatt gtgtttcagc ctttgtcaaa attcatcttt
    30541 aatataaaag agtcttttga taatatccga gttggtatca atttaatgtt atccaacatc
    30601 gcaagtagtt tgattatcgg tattgttcgt ctaggaatcc aatggaactg gaatatcgaa
    30661 acattcggga aagtatctct gaccttgagt gtttccaatc tattgatgac tttcattaat
    30721 gccattggac tagtcgtctt tccgctatta agacgaacaa aagcagaaaa cttacctaag
    30781 atttattcta atttaagaaa cgttttgatg cttatcatgt tcgcgatttt gctcatttac
    30841 tatcctttaa aaattgtatt agacctctgg ttgccagcct atcaagatgc cttgattttc
    30901 atgaccctta ttttccctat gtcagtctat gaagggaaaa tggcattggt cattaatact
    30961 tacttaaagg cattaagaat ggaaagagat atccttagag tcaatgcctt agtaatgttg
    31021 atcagtatgg gagtgaccct ggttacaaca tacctgttaa atagtttgga gctgactgtt
    31081 gtatcgatag ttgttttgct agctttgaga agtatcatag ccgaattaat tctgtctaaa
    31141 aaactggatg tttcggttaa gaaggatatt gtattagaat ttcttttgac gcttgtcttt
    31201 atttcttcaa gttggtattt gccgattggg ctggcagtaa ttgtctacac aatagcctac
    31261 ggtttatatc tctatttgaa acacgaagat atcaaaacct atttagctta ctttaaagct
    31321 agtaaaaaaa catcaaatta aaaaattata taatgattaa gtggtagatt ctatttctac
    31381 cgttttagat attcgggagg taatgatgaa aaaaattatg ttagtattcg gtacacgtcc
    31441 ggaagccatc aaaatgtgtc cattagtcaa tgagttgaaa aaacacgaag atatggaaac
    31501 aattgtgtgt gttactggac aacacaaaga gatggttagt cctgttttag atttatttgg
    31561 tgttgtacca gattatgatt tagaaattat gaaggctaac caaaccttgt tctctatcac
    31621 aactagtatc ttggaaaaga taaaaccagt tttagagaag gaacaaccag atattgtcct
    31681 agttcacggt gacactacga caacttatgc agcagccttg gcagcattct atttgggaat
    31741 taaagtagga catgttgaag ctggtttgcg aacgtacaat ttacaaagtc catttcctga
    31801 agaatttaac aggcaatcga catcaatcat tgcaacttac cattttgctc caactgagtt
    31861 ggctaaagaa aatctcttaa aagaaggtag agagaatgtt tatgtgactg gaaatactgt
    31921 cattgatgct cttacaacta ctgttcaaga ggattataca cacactcatt tagatttaaa
    31981 cgctaacaat cgtctcatct tattgactgc tcatagacgc gaaaatctcg gcgaaccgat
    32041 gagacatatg tttagagcag ttaaacgagt attgaatgaa tacgaagatg ttaaagtcat
    32101 ttatccaatt cataagaatc ctttggtacg tgaaacagct gcagagatct ttggagatac
    32161 agaacggatt caaattattg aacctttgga tgttcttgat ttccacaact tcatgaacca
    32221 aagttatatg attttaacag attctggcgg agttcaggaa gaagcacctt ctttaggaaa
    32281 acctgtattg gttatgcgcg atactactga aagacctgaa ggagtagcgg caggaacctt
    32341 gaaattagta ggaactgacg aagaaacaat ttatcaaaac ttcaaactac ttctagatga
    32401 ttctggagaa tacaaaaaaa tgagtcaggc tagcaatcca tacggtaatg gtgatgctag
    32461 tcaacagatt gttcagattt tgcgtgggat ttaagaagat tctctaaaag agtctaagag
    32521 gaatccactc cacaaacata aaactcttat gctatcattt atgattgaga tagactcata
    32581 acttaatatt tttatcctaa gaaaattcgt tcatattcaa tatgaatgaa aaacaacgaa
    32641 gaaaggttat ttcattatga aaggtattat tcttgcaggc ggctcaggta cccgcctgta
    32701 cccacttact cgggctgcgt caaaacagct gatgccggtt tatgataaac ctatgattta
    32761 ttatccgttg tcgacattaa tgttggctgg aattaaagat attttgatta tctcaactcc
    32821 tcaagatttg ccccgtttta aggacttgct cttggatggt tccgaatttg ggatcaagct
    32881 ttcctatgcg gaacaaccta gtcccgatgg acttgctcag gcttttctta tcggtgaaga
    32941 atttatcggt gacgatagcg ttgccttgat tttaggcgac aatatctacc atggtcctgg
    33001 tctgagcaca atgcttcaaa aagcagccaa gaaagagaaa ggtgcgactg tttttggcta
    33061 ccaagtgaag gatccagagc gttttggtgt ggttgagttt gatacagaca tgaatgctat
    33121 ttctatagaa gaaaaaccgg agtatcctcg ctccaactat gcagtgacag gactgtattt
    33181 ctatgataat gatgttgtgg agattgctaa acagatcaaa cctagtgctc gtggcgagtt
    33241 agaaattaca gacgttaaca aggcttacct aaatcgtggt gacctttctg ttgagctgat
    33301 ggggcgtggt tttgcctggt tggatacggg aacccatgaa agcttgctag aagcttctca
    33361 gtatattgaa acggttcagc gtatgcagaa cgttcaagtg gcaaatctag aagaaatttc
    33421 ctatcgtatg ggctacatta gtcgtgaaga cgtgctggaa ttggctcagc ctcttaagaa
    33481 aaatgaatac ggacaatatt tgctccgttt gattggagaa gcatagatgt cagataattt
    33541 ttttggaaag acacttgtgg tacgcaagat tgatgctata ccaggactgc tagagtttga
    33601 tattcccgtt catggagaca atcgtggttg gtttaaggaa aatttccaga aggaaaagat
    33661 gctaccgctt ggttttcctg aaagcttctt tgctgcaggg aaactgcaaa ataacgtcag
    33721 cttttctcgc aaaaatgttc ttcgaggact ccatgctgaa ccttgggaca agtatatctc
    33781 tgttgcagac gatgggaagg ttttaggatc ttgggtagat ttgcgtgaag gcgagacctt
    33841 tggaaatgtt taccagacag agattgatgc tagcaaggga atttttgtcc ctcgtggcgt
    33901 agccaacggt tttcaagtcc tctcagatac ggtttcctat agctatctgg tcaatgacta
    33961 ctgggctctt gaactcaaac ccaaatatgc ctttgttaac tatgctgacc cagcattggg
    34021 aattgagtgg gaaaacctag cggaagctga ggtttcagag gcagacaaac accatcctct
    34081 attaagggat gtcaaaccac ttacgaaaga cgagttgtaa aaggaaacat tatgactgaa
    34141 tacaaaaaaa ttatcgtgac aggtggagct ggttttatcg gttctaactt tgttcactat
    34201 gtttacaata actttacaga tgtccatgtg acagtgctgg acaagctgac ttatgcaggt
    34261 aatcgtgcca atattgaaga aattttaggc gaccgtgttg agttagtcgt tggagatatt
    34321 gctgatgcag ccttggtaga taagttagca gctgaagcgg atgccattgt acactatgcg
    34381 gcagaaagcc acaatgacaa ttcgcttaat gacccctcgc catttatcca taccaacttc
    34441 atcggaactt atacactctt ggaagcggct cgtaaatacg accttcgttt ccaccatgtg
    34501 tcgactgacg aagtctatgg ggatctgccg ctgcgtgaag atttaccagg tcatggggaa
    34561 ggaccaggtg agaaatttac ggctgaaacc aagtacaatc caagctcgcc ttactcatcg
    34621 actaaggcgg cttcagactt gattgtcaaa gcttgggtgc gctcatttgg tgttaaagca
    34681 acgatttcta actgttcaaa caactatggt ccttaccagc acatcgagaa gttcattccg
    34741 cgccagatta ctaatatctt gagcggtatc aagccaaaac tctacggaga aggtaagaat
    34801 gtgcgtgact ggattcatac taatgaccat tcatcaggtg tttggacgat tctgaccaag
    34861 ggtcaaatcg gtgaaaccta cctgattggt gcggatggtg agaagaacaa taaggaagtg
    34921 ttggaactca tcctcaaaga aatgggacag ccagctgatg cttatgacca cgtaacagat
    34981 cgagctggtc acgacctccg ctatgccatc gatgcaagca agctccgtga tgaactagga
    35041 tggaagccag agtttaccaa ctttgaagca ggtctcaaag cgactatcaa gtggtacaca
    35101 gataaccaag actggtggaa agcagaaaaa gaagctgttg aagccaatta tgctaagact
    35161 caggagatta ttacagtata aaaagcagga aatcgctgct ttttattgct atattgggaa
    35221 gagttacata ttagaaaggt ctagagatga ttttaattac aggggcaaat ggccaattag
    35281 gaacggaact tcgctattta ttggatgaac gtaatgaaga atacgtggca gtagatgtgg
    35341 ctgagatgga cattaccaat gaagaaatgg ttgagaaagt ttttgaagag gtgaaaccaa
    35401 ctttagtcta ccactgtgca gcctatactg ctgttgatgc agcagaggat gaaggaaaag
    35461 agttggactt cgccatcaat gtgacgggga cagaaaatgt cgccaaagca tctgaaaagc
    35521 atggtgcaac tctagtttat atttctacgg actatgtctt tgacggtaag aaaccagttg
    35581 gacaagagtg ggaagttgat gaccgaccag atccacagac agaatatgga cgcactaagc
    35641 gtatggggga agagttagtt gagaagcatg tttctaattt ctatattatc cgtactgcct
    35701 gggtatttgg aaattatggc aaaaacttcg tttttaccat gcaaagtctt gcgaaaactc
    35761 ataagacttt aacagttgta aatgaccagt acggtcgtcc gacttggact cgtaccttgg
    35821 ctgagttcat gacctaccta gctgaaaatc gtaaggaatt tggttattat catttgtcaa
    35881 atgatgcgac agaagacaca acatggtatg attttgcagt tgaaattttg aaagatacag
    35941 atgtcgaagt caagccagta gattccagtc aatttccagc caaagctaaa cgtccgctaa
    36001 actcaacgat gagcctggcc aaagccaaag ctactggatt tgttattcca acttggcaag
    36061 atgcattgca agaattttac aaacaagaag tgagataagt agtagaatga ttttctagtc
    36121 taataaaaga ggcagataat gaactcaaaa ggagcttaag gtgtacgatt atcttgttgt
    36181 tggtgctggt ctctttggtg cagtctttgc ccatgaagta gccttaaaag gaaaaaagta
    36241 aaagtcattg aaaaacggaa tcatatcgtg ggtaatatct atactcgtga agaggaagga
    36301 attcaagttc atcaatatgg tgctcatatc ttccatactt ctgataagga gagctgggat
    36361 tatgtaaatc agtttgcagg gtttaaccgt tacaccaatt ctcctgttgc aaactataag
    36421 ggtgagattt ataaccttcc ttttaatatg aatactttca ataaactctg gggagttgta
    36481 acgccagcag aagcacaagc taagattgag gaacaacgtg ctattttaaa tggtaaaact
    36541 cctgaaaatt tggaagaaca ggcgatttct cttgtaggta cagacatcta cgaaaaatta
    36601 atcaaagact atacagagaa acagtggggc aaaccaacta ctgaacttcc atcctttatt
    36661 attcgccgtt taccagtaca cctgacctat gataacaact attttaacga tacctatcaa
    36721 gggattccaa ttggtggata cactcaaata gttgaaaaat gttggattat gaaaatattg
    36781 atgtagaaac aaatgttgat ttctttgtga acaaagagca atatctgaaa gattttccta
    36841 agattgtctt tactggtatg attgatgaat tctttgacta taagttgggc gaactagagt
    36901 accgtagtct tcgttttgaa aatgagacct tggatatgga aaattaccaa ggaaatgcag
    36961 ttgtgaacta tacggatgca gaaaccccat atactcgcat tattgaacac aaacattttg
    37021 agtttgggag tcaagcaaag actatcatta ctaatagaac attctaaaac atgggaaaaa
    37081 ggtgatgagc cttattatcc agttaataat gatcgtaata atcatttgta taaatcatat
    37141 aaaaaacttg ctgatgagca agggaatgtt atctttggtg gccgcttagg acactatcgt
    37201 tattacgata tgcaccaagt aattggagca gctttgcagt gcgtgagaaa tgagttagat
    37261 tcatactcaa tgaaaattaa agagcaaact aggaagctag ccgcaggttg ctcaaaacac
    37321 tgttttgagg ttgcagatgg aagctgacgc ggtttgaaga gattttcgaa gagtataaac
    37381 aagtaaaact gactaccagt tattatttag aaatagtatt aaaaattcct tgactatatg
    37441 atatagttga gggattttta aatgatattc atattttttg caaagatgtt gtttgaaaaa
    37501 taattttcaa aaattctgaa aattctgttg acaactttct gaaaagagtc tataatggag
    37561 agaaagtttt aaaggagaaa atgatgaaaa gttcaagact atttgccctt gcgggcgtga
    37621 cattattggc ggcgactact ttagctgcat gctctggatc aggttcaagc actaaaggtg
    37681 agaagacatt ctcatacatt tatgagacag accctgataa cctcaactat ttgacaactg
    37741 ctaaggctgc gacagcaaat attaccagta acgtggttga tggtttgcta gaaaatgatc
    37801 gctacgggaa ctttgtgccg tctatggctg aggattggtc tgtatccaag gatggattga
    37861 cttacactta tactatccgt aaggatgcaa aatggtatac ttctgaaggt gaagaatacg
    37921 cggcagtcaa agctcaagac tttgtaacag gactaaaata tgctgctgat aaaaaatcag
    37981 atgctcttta ccttgttcaa gaatcaatca aagggttgga tgcctatgta aaaggggaaa
    38041 tcaaagattt ctcacaagta ggaattaagg ctctggatga acagacagtt cagtacactt
    38101 tgaacaaacc agaaagcttc tggaattcta agacaaccat gggtgtgctt gcgccagtta
    38161 atgaagagtt tttgaattca aaaggggatg attttgccaa agctacggat ccaagtagtc
    38221 tcttgtataa cggtccttat ttgttgaaat ccattgtgac caaatcttct gttgaatttg
    38281 cgaaaaatcc gaactactgg gataaggaca atgtgcatat tgacaaagtt aaattgtcat
    38341 tctgggatgg tcaagatacc agcaaacctg cagaaaactt taaagatggt agccttacag
    38401 cagctcgtct ctatccaaca agtgcaagtt tcgcagagct tgagaagagt atgaaggaca
    38461 atattgtcta tactcaacaa gactctatta cgtatctagt tggtacaaat attgaccgtc
    38521 agtcctataa atacacatct aagaccagcg acgaacaaaa ggcatcgact aaaaaggctc
    38581 tcttaaacaa ggatttccgt caggctattg cctttggttt tgatcgtaca gcctatgcct
    38641 ctcagttgaa tggacaaact ggagcaagca aaatcttacg taatatcttt gttccaccaa
    38701 catttgttca agcagatggt aaaaactttg gcgatatggt caaagagaaa ttggtcactt
    38761 atggggatga atggaaggat gttaatcttg cagattctca ggatggtctt tacaatccag
    38821 aaaaagccaa ggctgaattt gctaaagcta aatcagcttt acaagcagaa ggtgtgactt
    38881 tcccaattca tttggatatg ccagttgacc agacagcaac tacaaaagtt cagcgcgtcc
    38941 aatctatgaa acaatccttg gaagcaactt taggagcgga taatgtagtc attgatattc
    39001 aacaactaca aaaagacgaa gtaaacaata ttacatattt tgctgaaaat gctgctggtg
    39061 aagactggga tttatcagat aatgtcggtt ggggtccaga ctttgccgat ccatcaacct
    39121 accttgatat catcaaacca tctgtaggag aaagtactaa aacatattta gggtttgact
    39181 caggggaaga taatgtagct gctaaaaaag taggtctata tgactacgaa aaattggtta
    39241 ctgaggctgg tgatgagact acagatgttg ctaaacgcta tgataaatac gctgcagccc
    39301 aagcttggtt gacagatagt gctttgatta ttccaactac atctcgtaca gggcgtccaa
    39361 tcttgtctaa gatggtacca tttacaatac catttgcatt gtcaggaaat aaaggcacaa
    39421 gtgaaccagt cttgtataaa tacttggaac ttcaagacaa ggcagtcact gtagatgaat
    39481 accaaaaagc tcaggaaaaa tggatgaaag aaaaagaaga gtctaataaa aaggctcaag
    39541 aagatctcgc aaaacatgtg aaataactgt tgcaaaatat aagaaaggat ttagtatttc
    39601 tcttgaatgc tgaatccttt tttacatttg taaagaaaga ttctaaatgt actgaccccc
    39661 aaaagttgga gcctcttttt gtcagaatag agaaaatttt tgttaatttt acttgtttcc
    39721 tattgctttc tcagctatta tttgttatat taaaagtata attatttttt atttatcagg
    39781 gttaagcatt gcactttcag aggaaggagt attttttaaa aagaaaatgt aaacgcttgc
    39841 taaaaaatga aaggatttag aagtttatga ataaaggatt atttgaaaaa cgttgtaaat
    39901 atagtattcg gaaattttca ttaggtgttg cttctgttat gattggagct gcattctttg
    39961 ggacaagtcc ggttcttgca gatagcgtgc agtctggttc cacggcgaac ttaccagctg
    40021 atttagctac tgctcttgca acagcaaaag agaatgatgg acgtgatttt gaagcgccta
    40081 aggtgggaga agaccaaggt tctccagaag ttacagatgg acctaagaca gaagaagaac
    40141 tattagcact tgaaaaagaa aaaccggctg aagaaaaacc aaaagaggat aaacctgcag
    40201 ctgctaaacc tgaaacacct aagacggtaa cccctgaatg gcaaacggta gagaaaaaag
    40261 aacaaaaggg aacagtcact atccgagaag aaaaaggtgt ccgctacaac caactatcct
    40321 caactgctca aaatgataac gcaggtaaac cagccctgtt tgaaaagaag ggcttgaccg
    40381 ttgatgccaa tggaaatgca actgttgatt taaccttcaa agatgattct gaaaagggca
    40441 aatcacgctt tggtgtcttc ctgaaattta aagataccaa taataatgtt tttgtcggtt
    40501 atgacaagga tggctggttc tgggagtata aatctccaac aactagcact tggtatagag
    40561 gtagtcgtgt tgctgctcct gaaacaggat caacaaaccg tctctctatc actctcaagt
    40621 cagacggtca gctaaatgcc agcaataacg atgtcaatct ctttgacaca gtgactctac
    40681 cagctgcggt caatgaccat cttaaaaatg agaagaagat ccttctcaag gcgggctctt
    40741 atggcaatga ccgtacggtt gtcagcgtta aaacagacaa tcaagaaggc gtaaaagcgg
    40801 atgatactcc tgcccagaaa gaaacaggtt cggttgttga cgatagcaag gtgacttatg
    40861 atacgatcca gtctaaggta cttaaggcag taattgacca agccttccct cgtgtcaagg
    40921 aatacacctt gaatggacat actttgccag gacaggtgca acagttcaac caagtcttta
    40981 tcaataacca ccgaatcacc cctgaagtca cttataagaa aatcaatgag acaacagcag
    41041 agtacttgat gaagattcgc gatgatgctc acttaatcaa tgcggaaatg acagtacgct
    41101 tgcaagttgt ggacaatcaa ttgcactttg atgtgaccaa gattgtcaac cacaatcaag
    41161 tcactccagg tcaaaagatt gatgacgaaa gaaaactact ttcttctatt agtttcctcg
    41221 gcaatgcttt agtctctgtt tctagtgatc aaactggtgc taagtttgat ggggcaacca
    41281 tgtcaaacaa tacgcatgtc agcggagatg atcatatcga tgtaaccaat ccaatgaagg
    41341 atttggctaa gggttacatg tatggatttg tttctacaga taagcttgct gctggtgttt
    41401 ggagtaactc tcaaaacagc tatggtggtg gttcgaatga ctggactcgt ttgacagctt
    41461 ataaagaaac agtcgggaat gccaactatg taggaatcca cagctctgaa tggcaatggg
    41521 aaaaagctta taagggcatt gttttcccag aatacacgaa ggaacttcca agggctaagg
    41581 ttgttatcac tgaagatgcc aatgcagaca agaaagtcga ttggcaggat ggtgccattg
    41641 cttatcgtag cattatgaac aaccctaaag gttgggaaaa agttaaggat atcacagctt
    41701 accgtatcgc gatgaacttt ggttctcaag cacaaaaccc attccttatg accttggatg
    41761 gtatcaagaa aatcaatctc cacacagatg gtcttgggca aggtgttctc cttaaaggat
    41821 atggtagtga aggtcacgac tctggtcact tgaactatgc tgatattggt aagcgtatcg
    41881 gtggtgtcga agacttcaag accctaattg agaaggctaa gaaatatgga gctcatctag
    41941 gtatccacgt taacgcttca gaaacttatc ctgagtctaa atacttcaat gaaaaaattc
    42001 tccgtaagaa tccagatgga agctatagct atggttggaa ctggctagat caaggtatca
    42061 acattgatgc tgcctatgac ctagctcatg gtcgtttggc acgttgggaa gatttgaaga
    42121 aaaaacttgg tgacggtctc gactttatct atgtggacgt ttggggtaat ggtcaatcag
    42181 gtgataacgg tgcctgggct acccacgttc ttgctaaaga aattaacaaa caaggctggc
    42241 gctttgcgat cgagtggggc catggtggtg agtacgactc taccttccat cactgggcag
    42301 ctgacttgac ctacggtggc tacaccaata aaggtatcaa cagtgccatc acccgcttta
    42361 tccgtaacca ccaaaaagat gcttgggtag gggactacag aagttatggt ggtgcagcca
    42421 actatccact gctaggtggc tacagcatga aagactttga aggctggcaa ggaagaagtg
    42481 actacaatgg ctatgtaacc aacttatttg cccatgacgt catgactaag tacttccaac
    42541 acttcactgt aagtaaatgg gaaaatggta caccggtgac tatgaccgat aacggtagca
    42601 cctataaatg gactccagaa atgcgagtgg aattggtaga tgctgacaat aataaagtag
    42661 ttgtaactcg taagtcaaat gatgtcaata gcccacaata tcgcgaacgt acagtaacgc
    42721 tcaacggacg tgtcatccaa gatggttcag cttacttgac tccttggaac tgggatgcga
    42781 atggtaagaa acttcctact gataaggaaa agatgtacta cttcaatacg cagactggtg
    42841 caacaacttg gacccttcca agcgattggg cagagagcaa ggtttacctt tacaagctaa
    42901 ctgaccaagg taagacagaa gagcaggaac taactgtaaa agatggtaaa attaccctag
    42961 atcttctagc aaatcaacca tacgttctct atcgttcgaa acaaaccaat cctgaaatgt
    43021 catggagtga aggcatgcac atctatgacc aaggatttaa tagcggtacc ttgaaacatt
    43081 ggaccatttc aggcgatgct tctaaggcag aaattgtcaa gtctcaaggg gcaaacgata
    43141 tgcttcgtat tcaaggaaac aaagaaaaag ttagtctcac tcagaaatta actggcttga
    43201 aaccaaatac caagtatgcc gtttatgtcg gtgtcgataa ccgtagtaat gccaaggcaa
    43261 gtatcactgt gaatactggt gaaaaagaag tgactactta taccaataag tctctcgcgc
    43321 tcaactatgt taaggcctac gcccacaata cacgtcgtga taatgctaca gttgatgata
    43381 caagttactt ccaaaacatg tacgccttct ttacaactgg atcggacgtc tcaaatgtta
    43441 ctctgacatt gagtcgtgaa gctggtgatc aagcaactta ctttgatgaa attcgtacct
    43501 ttgaaaacaa ttcaagcatg tacggagaca agcatgatac aggtaaaggc accttcaagc
    43561 aagactttga aaatgttgct cagggtatct tcccatttgt agtgggtggt gtcgaaggtg
    43621 ttgaagataa ccgcactcac ttgtctgaaa aacacgatcc atatacacaa cgtggttgga
    43681 atggtaagaa agtcgatgat gttatcgaag gaaattggtc actcaagaca aatggactag
    43741 tgagccgtcg taacttggtt taccaaacta ttccgcaaaa cttccgtttt gaagcaggta
    43801 agacctaccg tgtaaccttt gaatacgaag caggttcaga caatacctat gcttttgtag
    43861 tcggtaaggg agaattccag tcaggtcgtc gtggcactca agcaagcaac ttggaaatgc
    43921 atgaattgcc aaatacttgg acagattcta agaaagccaa gaaggcaacc ttccttgtga
    43981 caggtgcaga aacaggagat acttgggtag gtatctactc aactggaaat gcaagtaata
    44041 ctcgtggtga ttctggtgga aatgccaact tccgtggtta taacgacttc atgatggata
    44101 atcttcaaat cgaagaaatt accctaacag gtaagatgtt gacagaaaat gctctgaaga
    44161 actacttgcc aacggttgcc atgactaact acaccaaaga gtctatggat gctttgaaag
    44221 aggcggtctt taacctcagt caggccgatg atgatatcag tgtggaagaa gcgcgtgcag
    44281 agattgccaa gattgaagcc ttgaagaatg ctttggttca gaagaaaacg gctttggtag
    44341 cagatgactt tgaaagtttg gatgcgccag ctcaaccagg tgaaggtctt gagaatgcct
    44401 ttgatggaaa cttatctagt ttatggcata catcatgggg cggaggagat gtaggcaagc
    44461 ctgcaaccat ggtcttgaaa gaaccaactg aaatcactgg acttcgttat gttccacgtg
    44521 gatcaggttc aaatggtaac ttgcgtgatg tgaaacttgt tgtgacagat gagtctggca
    44581 aggagcatac ctttactaca actgattggc cagataacaa taagtcaaaa gatattgact
    44641 ttggtaagac aatcaaggct aagaaaattg tccttactgg taccaagaca tacggagatg
    44701 gtggagataa ataccaatct gcagcggaac ttatctttac tcgtccacag gtagcagaaa
    44761 cacctcttga cttgtcaggc tatgaagcag ctttggctaa ggctcagaaa ttaacagaca
    44821 aagacaatca agaggaagta gctagcgttc aggcaagcat gaaatatgcg acggataacc
    44881 atctcttgac ggaaagaatg gtggaatact ttgcagatta tctcaaccaa ttaaaagatt
    44941 ctgctacgaa accagatgct ccaactgtag agaaacctga gtttaaactt agctctttag
    45001 cttccgatca aggtaagacg ccagattata agcaagaaat agatagacca gaaacacctg
    45061 aacaaatctt gccagcaaca ggtgagagtc aatctgacac agccctcttc ctagcaggtg
    45121 ttagcctagc cctatctgct ctctttgtag taaaaacgaa gaaagactag tatttagtaa
    45181 aacctcttaa caagattacg gaagcagtct ctatcttttc caatgaggtt tatagtacag
    45241 aaaaaatctg agaagatgtc ttctcagact tttgttaagc acataaatac aatagtgcta
    45301 tgacaaaatc acccagaaaa tctgggtgat aaatgttatg gttgtgctgg ttgaggattc
    45361 tgattttgtt gatcaggggt tgtatttgat tgttgcgtat tattgttagg attggtagtc
    45421 gtactattat ttgtgcttgg agtggttgag ctagactgtg aagttgaact atctgatgat
    45481 gagcttgaac tttcagttga tgggggttgt tgtggagcag gtgagctcca cgtagaacga
    45541 gcaccatttt taaatacgaa ttctccattt ctgtagagcc cctctggtat attccaatcc
    45601 tctggattgc ttccttcaga caggtaggtc atcatagagc gataaacttt agctgcaact
    45661 aggaaaccat ctccaacgat aggagttaaa cgattcgaat aacctgtcca tacagccata
    45721 gaatacttac gagtataacc cacaaacatt tcatctggag ctacgtagcc agtgttcttg
    45781 atatactttt caatttcttc gtcagtatag ttagaagtac ctgtcttacc tgcttgtgga
    45841 agccatggta ggtaggctcc acgtcctgtt ccgtaagtta aaacagtttt catcatttca
    45901 gtcatcatat aggcagtagt ctctttcata gctcgtgtac cagcatcaga aaattctttt
    45961 tcgctaccat cactaaagac gattttattg atatacattg gtttgtgata aataccacca
    46021 ttagcaaaag cagcgtaggc agcagccatt ttttcactac ttgcaccata ttttttgttg
    46081 gattcagttg tgttacttga aatggcgttt gcataatgca tgcttggata gtcgatacca
    46141 agaccattaa ggaaggtttt agctctatct agaccgacct tattcaaagt ctcaacggct
    46201 gtgacatttc gtgattgttg aagagcatac tggattgtaa tgtttccaaa gtagacatga
    46261 tcccagttgt agagtggagt atcagtgcca ggatagttat aagggacatc atgtacaata
    46321 gaagcagtag agtcatagac tccatattct aaagcgggag catagtcagt gattggtttc
    46381 attgatgatc cccagtcacg attggtttct acggcctggt tggtaccgaa tgaaacatta
    46441 cttgcttgat gacgagcacc aagttgtgcg atgactttac catttgaaac atctacgacc
    46501 gtagatgcga cttgcaaatc atcgtcaggg taagagacgt attgatcgga gttgtagata
    46561 tcccacagat gtttttgagc ttcttggtct acatttgtgt aaacatccat cccagtagtt
    46621 agaaggttat agccagtttc ttgttctact tggtcgataa cctctttgag ataattgtcc
    46681 atatatgctg gatagctatt gaccgatttc aaactttgga gtccatcagt aataggggta
    46741 ttaatagcct tctcatactg ttcggcagaa atgtagcctt gacctttcat ctctgaaagt
    46801 accaagttac gacggtcaag ggcagcttct ggatgagaat agggatcgta ttgattcgga
    46861 gcctgtggca ttcctgctag tagggcaagt tgaggtaatg atagttctcg caaatctttg
    46921 ccgtaatagt tttgggcagc cgtctgcatt ccatagtttc cgttagacat gtaaacttta
    46981 ttcacatagt aggtcaggat ttcttgtttt gtggcttttt gttctaattg aacagccaac
    47041 caagcttcct gggctttacg tgaaatggtc tgatcagaag tggaagttga gaaataggtc
    47101 aacttaatta attgttgggt aagggtagat cctccctgga gggagttgtt ttgtaagtta
    47161 cgtaaaaaag ctcctataat tcggatggta tcgacaccgc gatgatcgaa aaaacgatgg
    47221 tcttcgatcg atacgatagc cttgaccaaa tcagtaggaa tttcgttggc ctgagcgttt
    47281 actcggcgtt cagagcccag atcggcaatc agttcgtttt tactatcgaa aatcttacta
    47341 gacgtggttg cgactaattt gctctcagat agggctgggg ctttgctgac gtaatagaga
    47401 aatatgcctc ctcccagcat aactgctgtg ataaataaag ttaagaagca gatactcaca
    47461 tacttagcta ttcgcaggat agtttgtttg ttcatcttgt tttaccacct aataaatgtt
    47521 ctttgataac attgagatag ggaatttgag ggaaggcacc agccttgatt tcatatccat
    47581 attctcgaat atatccaagt ggcattgatt tttgcccctt atcttgatga tagaagcgaa
    47641 tcaaatcata tgccggtaat aagtaggttt cttgctgaga agaaaagtga agaaggacaa
    47701 agcagattcc ttgttgagca aggatttgtt ccatatgctg aatctgatgt ggatggaaat
    47761 ttttcatcgg aatcgcacgt ttttgttttg tttccttggc ttcaaagtcg atgtaatatc
    47821 cattataaac gccagaatag tccgtcgttg aagcttgtcg aaaataggct tcaacaatct
    47881 tggcacgact tcgttgtgga tagtccactc gtacgatttg aataggagtt ggtttcttgt
    47941 gtataacagc caagccctga gacaaatagt agtcgttggt agcattgatc atcttttcaa
    48001 aagacattcc tcgatttgcg aaatttttgg gttgagaaag agatggttgt cttttttgtg
    48061 atgaaagttt atgtggatag ttgaccataa ttctccttat tggtacaata acatcactct
    48121 attataccat aaatttgcac agaaagggtt aaaaatggct acagctttgg ttttgggcta
    48181 ttctgctttt gatttgggtt tattttctga taaggatcct cgtcttaaat tgataaaaaa
    48241 agcaatacgt aaagatttag aggctatggc agcagatggg gtgtcttggc ttgtgtttac
    48301 agggactttg ggctttgaat attgggtttt agaggttgct caggagatga aaaccgagta
    48361 cggtttccag ttggccacca tttttgcttt tgaaacccat ggggaaaatt ggaatgaagg
    48421 caatcagatg aaactgagtc gttttaagca ggtagacttt gtcaaatatg cttatcctcg
    48481 ctatgagcac aaggggcagt taagagatta ccagcagttt ttgctggaaa acacgactag
    48541 ttcctatctt ttttatgatg aagaaaatga aacgaaacta gcttattttt accaaaagat
    48601 gaaaaatcaa gaggactatt ttataaagag attaacattt gatcaattaa atgaacttgc
    48661 tgaaaatttt tccgaaaatt gaagctttga ccttgatttt tgtttgcctt tttttatata
    48721 ataatactag caagcgagaa tggagagaga catgacaagt attatttttt cagcaaaaga
    48781 tatttttgaa caagagtttg gacgtgaagt tcgtgggtat agcaaggtag aagttgatga
    48841 gtttttagac gatgtcatca aggactatga aacctatgct gccttggtta agtcacttcg
    48901 tcaggagatt gcggatttga aggaagaatt aactcgtaaa ccgcaagtga gttcggctcc
    48961 aagtcctagt cacccagatc caattgatgt ggctgcttca tcttctatga cgaattttga
    49021 tattttgaaa cgcttgaatc gtcttgaaaa agaagtattc ggtaaacaaa ttttagacaa
    49081 tactgatttg taattcaggt cttgttacat gcaatttttg gataatcgcg tgaggagaat
    49141 tgcttctcat gaggaaagtc catgctagca caggctgtga tgcctgtagt gtttgtgcta
    49201 ggcgaaacca taagcctagg gacgagaaat cgttacggca gttgaaatgg ctaagtcctt
    49261 ggataggcca gagtaggctt gaaagtgcca cagtgacgga gtctttctgg aaacagagag
    49321 agtggaacgc ggtaaacccc tcaagctagc aacccaaatt ttggtcgggg catggagtac
    49381 gcggaaacga acgtagtatt ctgactgcta tcagctagag ctgctagtgg tagacagatg
    49441 attatcgaag gaagtggtcc tagtcatttc tggaacaaaa catggcttat agaaaattgc
    49501 atataggttg gggctgagaa attttctcaa cctcattttt taaagtggac atatagaaag
    49561 gtcttgcaag actgtaacat gaaaaaagaa tttaatttaa ttgcaactgt ggcagcaggt
    49621 cttgaagctg ttgtaggacg agaagtaaga gagctgggct acgattgtca ggttgaaaat
    49681 gggcgtgtgc gttttcaagg agacgtgaga gcgattatcg aaaccaacct ctggcttcgg
    49741 gcagcagatc gtatcaagat catcgtagga acgttcccag ctaagacgtt tgaagagttg
    49801 tttcagggag tttttgcttt agattgggaa aattatttac cactcggagc tcggttccca
    49861 atttcaaaag ccaaatgtgt taaatctaaa cttcacaatg aacccagtgt tcaggctatt
    49921 tctaagaaag ctgttgtcaa gaaattgcag aaacactatg ctcgcccaga aggggttcct
    49981 ctgatggaga atggcccaga gtttaagatt gaggtctcta ttctcaaaga tgtggcaact
    50041 gtcatgattg atacgacagg ctctagcctc tttaaacgtg gttatcgtac cgaaaaaggg
    50101 ggagccccta tcaaggaaaa catggcggca gccattttac aactttctaa ctggtatcca
    50161 gacaagcctt tgattgatcc gacatgtggt tcggggactt tctgtatcga ggcggtcatg
    50221 attgctcgaa agatggctcc aggtcttcgt cgctcctttg cttttgagga atggaattgg
    50281 gtcagcgatc gcttgattca ggaagtgcgt acagaagcgg ctaaaaaagt agaccgtgag
    50341 cttgaactgg atattatggg ctgtgatatc gatgcacgta tggtggaaat tgctaaggcc
    50401 aatgctcagg cagctggtgt tgcaggagac attactttta agcagatgcg cgttcaggat
    50461 ttacgttctg ataaaattaa tggtgtaatc atttccaatc cgccttatgg tgaacgttta
    50521 tcagatgatg caggagttac caagctctat tctgagatgg ggcaagtatt tgcaccactg
    50581 aaaacttgga gcaaatttat cctgactagt gatgaagcct ttgaaagcaa gtatggtagc
    50641 caagcagata agaagcgtaa gttatacaac ggaaccttga aagtggatct gtatcaatat
    50701 tttggtcagc gtgtcaaacg gcaagaggta aaatagaaag ggatactcat gagtaaaaaa
    50761 agacgaaatc gtcataaaaa agaaggtcaa gaaccgcaat ttgattttga tgaagcaaaa
    50821 gagctaacag ttggtcaagc gattcgtaaa aatgaagaag tggaagcagg agtcttgtct
    50881 gaggattcca ttttggacaa gtatgtcaag caacacagag atgaaattga ggcggataag
    50941 tttgcgactc gtcaatacaa aaaagaggag ttagtcgaaa ctcagagtct ggatgattta
    51001 attcaagaga tgcgtgaggc tgtagaagag tcagaagctt attcggagga agttccatct
    51061 tctgaagaca tcttaccacc cttgcctctg gatgatgagg agcaaggctt ggatcctcta
    51121 ttactagagg atgaaaatcc aacagaaatg actgaagaag tggaagagga gcaaaatctt
    51181 tctcgtctgg aacaagaaga gtcagaaaag aaaagcaaaa aaggctttgt tttaaccgct
    51241 ttggcgcttg tatcagtgat tatctgtgtc agtgcttatt atgtctatcg tcaagtgaat
    51301 cgctcgacca aggaaattga aacttctcaa tcaactacag ccaatcaatc ggatgtggat
    51361 gattttaata cactttatga cgccttctac acagacagta ataaaacggc tttgaaaaat
    51421 agccagtttg ataaactaag tcaactcaag accttacttg ataagctgga aggtagtcgt
    51481 gaacatacgc ttgccaaatc taaatatgat agtctagcaa cgcaaatcaa ggccattcaa
    51541 gatgtcaatg cacaatttga aaaaccagct attgtggatg gtgtgttgga taccaatgcc
    51601 aaagccaaat cggatgctaa atttacagat attaaaactg gaaatacgga gcttgataaa
    51661 gtgctagata aggctatcag ccttggtaag agccagcaaa caagtacttc tagctcaagt
    51721 tcaagtgaaa ctagtagctc aagcactagt caaacaagct caaatacgac tagtgagaca
    51781 agcccaagta gttcaaatga gactagaagt agtcgcagtg aagtcaatat gggtctctcg
    51841 agtgcagggg ttgctgttca aagaagtgcc agtcgtgttg cctataatca gtctgctatt
    51901 gatgatagta acaactctgc ctgggatttt gcggatggtg tcttggaaca aattctagct
    51961 acttcacgtt cacgtggcta tatcactgga gaccaatata tccttgaacg tgtcaatatc
    52021 gttaatggca atggttatta caacctctac aagccagatg gaacctatct ctttaccctt
    52081 aactgtaaga caggctactt tgtcggaaat ggcgctggtc acgcggatga cttggactac
    52141 taagcagtcg ttacaaaatt ctttcttttc aaaagtaaaa atgataaaat aaaacaaatg
    52201 aaacaagagg agtgtcaaat gacaaaagct aactttggtg tcgtaggtat ggccgtaatg
    52261 ggtcgtaacc ttgcccttaa tattgaatct cgtggttaca cagttgctat ttacaaccgt
    52321 agtaaagaaa aaactgaaga tgtaattgct tgccatcctg aaaagaactt tgtaccaagc
    52381 tatgacgttg aaagttttgt aaactcaatc gaaaaacctc gtcgtatcat gctgatggtt
    52441 caagctggac ctggtacaga tgctactatc caagcccttc ttccgcacct tgacaagggt
    52501 gatatcttga ttgacggtgg aaatactttc tacaaagata ccatccgtcg taatgaagaa
    52561 ttggcaaact caggtatcaa ctttatcggt actggagttt ctggtggtga aaaaggtgcc
    52621 cttgaaggtc cttctatcat gcctggtgga caaaaagagg cctacgaatt ggttgcggat
    52681 gttcttgaag aagtctcagc taaagcacca gaagatggca aaccatgtgt gacttacatc
    52741 ggccctgatg gagctggtca ctatgtgaaa atggttcaca atggtattga gtacggtgat
    52801 atgcaattga tcgcagaaag ctatgacttg atgcaacact tgctaggcct ttctgcagag
    52861 gatatggctg aaatctttac tgagtggaac aagggtgaat tagacagcta tttgatcgaa
    52921 atcacagctg atatcttgag ccgtaaagac gatgaaggcc aagatggacc aatcgtagac
    52981 tacatccttg atgctgcagg taacaaggga actggtaaat ggactagcca atcatctctt
    53041 gaccttggtg taccattgtc actgattact gagtcagtgt ttgcacgcta catttcaact
    53101 tacaaggaag aacgtgtaca tgctagcaag gtgcttccaa aaccagctgc cttcaacttt
    53161 gaaggagaca aggctgaatt gattgaaaaa atccgtcaag ccctttactt ctcaaaaatc
    53221 atttcatacg cacaaggatt tgctcaattg cgtgtagcct ctaaagaaaa caactggaac
    53281 ttgccatttg cagatatcgc atctatctgg cgtgatggct gtatcatccg ttctcgtttc
    53341 ttgcaaaaga ttacagatgc ttacaaccgt gatgcagacc ttgccaacct tcttttggat
    53401 gaatacttct tggatgttac tgctaagtat caacaagcag tgcgtgatat cgtagctctt
    53461 gcggttcaag ctggtgtgcc agtgccaact ttctcagcag ctattactta ctttgatagc
    53521 taccgttcag ctgaccttcc agctaacttg atccaagcac aacgtgacta ctttggtgct
    53581 cacacttacc aacgtaaaga caaagaagga accttccact actcttggta tgacgaaaaa
    53641 taagtaggtc agccatgggg aaacggattt tattacttga gaaagaacga aatctagctc
    53701 attttttaag tttggaactc cagaaagagc agtatcgggt tgatctggta gaggaggggc
    53761 aaaaagccct ctccatggct cttcagacag actatgattt gattttattg aacgttaatc
    53821 tgggagatat gatggctcag gattttgcag aaaaattgag tcgaactaaa cctgcctcag
    53881 tcatcatgat tttagatcat tgggaagact tgcaagaaga gctggaagtt gttcagcgtt
    53941 ttgcagtttc atacatctat aagccagtcc ttatcgaaaa tctggtagcg cgtatttcgg
    54001 cgatcttccg aggtcgggac ttcattgatc aacactgcag tctgatgaaa gttccaagga
    54061 cctaccgcaa tcttaggata gatgttgaac atcacacggt ttatcgtggt gaagagatga
    54121 ttgctctgac ccgccgtgag tatgaccttt tggcgacact tatgggaagc aagaaagtat
    54181 tgactcgtga gcaattgttg gaaagtgttt ggaagtatga aagtgcgacc gagacaaata
    54241 tcgtagatgt ctatatccgc tatctacgga gcaagcttga tgttaaaggc caaaaaagct
    54301 acattaaaac cgtgcgtggt gttggttaca ccatgcaaga atagaaaagc agttgcagtt
    54361 gtgtaactgc ttttttgagg agtttttata tattgacatg cagtcgggtc tttgctacaa
    54421 tcgttttagg agggtatata gatgaaaatt ttgaaaaaaa tgatgcaagt tctactagca
    54481 gtctttttct ttggtttgct agctacaaat acggtatttg cgaataccac aggtggccga
    54541 tttgttgata aggataatag aaaatattat gtaaaagatg atcataaagc aatctattgg
    54601 cataaaatag acggtaaaac ctactatttt ggtgatggag gagagatggt tgtcggttgg
    54661 caatacttag aaattcctgg aacaggttat cgtgataatt tattcgataa ccaaccagtt
    54721 aatgaaattg gccttcagga gaagtggtac tattttggac aagatggtgc tttgttagaa
    54781 caaacagata aacaagtact agaggcaaaa acgtctgaaa atacaggaaa agtatacggt
    54841 gaacaatatc ctctatctgc tgaaaagaga acttattatt ttgataataa ttatgttgta
    54901 aagacaggct ggatttatga agacggcaat tggtattatt taaataagct aggaaatttt
    54961 ggcgatgatt cttacaatcc actaccaatt ggtgaagttg ctaagggttg gactcaagat
    55021 tttcatgtta ctattgacat tgatagaagc aaacctgctc catggtacta cctagatgct
    55081 tccggtaaga tgcttacaga ttggcaaaaa gtaaacggaa aatggtatta ttttggctcc
    55141 tctggttcta tggcaacagg ttggaaatat gtacgaggca aatggtatta cttagataat
    55201 aaaaatggtg atatgaagac tggttggtat caagatggtt caacttggta ctatttagat
    55261 ccttctaatg gagatatgaa aataggttgg acaaaagtaa atggaaaatg gtattatctc
    55321 aattcaaatg gagcaatggt tacaggtagt caaactatcg atggtaaagt ttataacttc
    55381 gcttcatctg gtgagtggat ttaatgttgg aggatatata aaatgaagct tttgaaaaaa
    55441 actatgcaag ctggactaac agtaattttc tttggtttgc tagctacgaa tacagtattt
    55501 gcagataact ctgaaggatg gcagtttgtc caagaaaacg gtagaaccta ttacaaaaag
    55561 ggggacctca aagaaaccta ctggctagtg attgatggta agtactatta ttttgattct
    55621 ctatctggag agatggttgt cggctggcaa tatatcccgt ttccatctaa aggtagtaca
    55681 attggtcctt acccaaatgg tatcagatta gaaggttttc caaagtcaga gtggtactac
    55741 ttcgataaaa atggagtgct acaagagttt gttggttgga aaacattaga gattaaaact
    55801 aaagacagtg ttggaagaaa gtacggggaa aaacgtgaag attcagaaga taaagaagag
    55861 aagcgttatt atacgaacta ttactttaat caaaatcatt ctttagagac aggttggctt
    55921 tatgatcagt ctaactggta ttatctagct aagacggaaa ttaatggaga aaactacctt
    55981 ggtggtgaaa gacgtgcggg gtggataaac gatgattcga cttggtacta tttagatcca
    56041 acaactggta ttatgcaaac aggatggcaa tatctaggta ataactggta ctacctccgt
    56101 tcatcaggag caatggccac tggctggtat caggaaggta ccacttggta ttatttagac
    56161 cagccaaatg gtgatatgaa aacaggatgg caataccttg gtaacaagtg gtactacctc
    56221 cgttcatcag gagcaatggt aactggctgg tatcaagatg gtttaacttg gtactaccta
    56281 aatgcaggta atggagacat gaagacaggt tggttccagg tcaatggcaa atggtactat
    56341 gcttatagct caggtgcttt ggcggtgaat acgaccgtag atggctacta cgtcaactat
    56401 aatggcgaat gggttcggta atgacagggc gcttataatt atattagaac actcgcttaa
    56461 tcaaagaagt gactttgttg tacttgacct gacgattggg gagattaaaa gcatgtgaaa
    56521 tctacacatg ctttttcgtt agttatgagt gttgaacttg actaaccatt gacaaaagat
    56581 aagagcaatc aaaataagat acaaaaatat caatgctaac tgcaccgaaa cgcccgatgc
    56641 tatggacagg gctaataggg agagcaggga cggggcgaga atgtctactg tgctcagagc
    56701 agagcccacc gtccccatct tgtcactggg gatatgggca aagacagctg cttgtaggcg
    56761 agggctgaga atgccgataa tcgtagaact gatgaaactg gtcatgaaaa ttacgatata
    56821 ggcttgacaa aggatactag ttattagagc caatagggaa atctcacaga aaaccaagag
    56881 gtgcgtgaaa cggatatttt taaatagatt actgctggtc atattgccaa ggatagctcc
    56941 acaagaaatg atgatggaga gcatggcgag gagttgccca atgctcagtt gtgctagtgt
    57001 ctgttggatg aagcggaggg caatcagccg aggggacaca tccaagatgg caatcatact
    57061 ggtcgtcaga aacagtagta tgacggtatc ttttaacctc aggagcacag ccagcgactg
    57121 tttaagatgt tgaaaatatt tcttaaaact cagtgctgta tgtgacattt caatcctttt
    57181 ttcaacctca tacaaggtat gtctaataac atacagaccc aaaaaggcaa tgacaaaagt
    57241 cagagtgttg ataagggaaa tagtttgaat actcataaca ttgataagga atgcgccagc
    57301 cagattggcg acaatgtgga caaccctcat cagagactgc ctgaacccca tggcatcatg
    57361 caggtcgtcc ttaattacac tgatgtagag ggcgttcatc atgtaggcag acaggtagct
    57421 caaggtgtca gagatgaggt tgatgatgac aatcataatg actgaaacta atgaaaaggg
    57481 cgacaagacg agaaatactg tcaaaatagc gtagagcagg attttgattt tggcaatcca
    57541 gagtgcgtgt ttgactctat tttcttgaaa atctcctaga atcccgagaa agagttgcga
    57601 tagtagggga accatctctg aaatggaaat cagtaaaatc gctagcggag cgaaattgta
    57661 ctgagccaca taattgataa tggcgaggta gaaaatactg tcgccgaatg atgaaaaaca
    57721 gctgtttagc agcaactgtc tatatatgtt gtttgtccaa aataatttca tacttttctc
    57781 cttatgtctg cacatcgaat gggaatttat tatttaatag acaccaatat accccatgct
    57841 tcctattccg aagtcaaaca aatctgtttt accactatct ccttgaaaca tcagtaaacc
    57901 gtgatcatct cgttcagaac atgctaaaat tacctgttgg attttttcat cagtaatttg
    57961 ttttgattgt agacagtggt ttgtagtaag ctagttattc cgtggcaata tcctgtcatc
    58021 atttttagat gatggttaaa aacaaattct tgatatttac taataatatc tttgtttccg
    58081 tcacaatcgt acatacaaag atataagatt attccggaaa ttccttcgca ccaagaaagt
    58141 tgtaaatttc ctaaattttc agtattagaa gtaacttttt ctaataattt ttttaattca
    58201 gcatggaatg tatggagatc attatagaac atagaaggtt ctaagacttt agaataggca
    58261 aataaagcat atgcaatttc acaatatcca tgagcaaagc tatagtctaa aatgctttct
    58321 ttggctgtat ctctttgtag gaaataatga taaatttccc catatactat tgtggatgaa
    58381 agttttaaga gtattgtcat tggtaaattg atagtatttt attaatgata ataggacacc
    58441 agattttccc aatgcaaagt ctatttcctc tagagtatca taattctcta ttaatttctt
    58501 agcggtgacg tttgctaatt gtagatagta ttgattttta ctgatagaaa ataaatgtag
    58561 gagtaaccat agatagcctg catcaccaaa agatagcctg catcaccaaa tagcagtgag
    58621 tattgatatt catatgtgtg tgtcgttcta attgtcactg ccttcttgat gatagagagt
    58681 attttagaat ccagttctgg ggggtacaat ttatttagag gaaacagtag tccagctatt
    58741 ccgtgttgga atgataaatt acttacgaaa tttccaaatt ctgttgaaga agtgatcctt
    58801 ccttcagaat ttacagtttt atctagtaaa aatcgtagaa cactattaca ttctgttttg
    58861 taatcatatt tatgttcctc tattttttta attttgacta aattatttgt ttgacttaaa
    58921 tttagtagac attgtaacca aaatagttgc tcatctgtga gctgaccttg agtatgtgat
    58981 agttctagta attgaatagg atcctttagt tagattcaat caatctataa cacaacaaca
    59041 taataacact tttaggataa cttatcaaat attatagtaa aatgaaataa taacaggaca
    59101 aatcgatcag gacagtcaaa tcgatttcta aaaatgtttt agaagtagag gtgtactatt
    59161 ctagtttcaa tctactatag tatatatttt tacatcttga attgtcaaat taagtgcata
    59221 agtttcccgt agcatacttc ataaggcgtt ttccacttaa gaaattttcg tggtcgatta
    59281 tttagaacct gtattcacaa aaaaatgtta aactagagtt atgatacgta aagcatatga
    59341 tactgattta aacgatcaag aatgggcgaa gattgaaccc tatttctcca aacaccgcac
    59401 ctataaatgg ccgaaacgag tacttgttaa tgagactttg tacgtcacta aaacaggttg
    59461 tcaatggcgc atgctccctc acgactttcc tctttactta atggtatgga gtttctttcg
    59521 tcgttctatg acgacaggtt ggttccaggt caatggcaga tggtactacg cttatagctc
    59581 aggtgccttg gcagtgaata cgaccgtaga tggctattct gtcaactata atggcgaatg
    59641 ggctcaataa tgaaagaagc gattgtgaat ggaaacaatc gctttttttg tgaaaatata
    59701 ataaaataga taggaaagaa ttaatacttg tatgaaaaat aagacgtttt ttcgtctagt
    59761 aaaaggaaaa aatgacaaaa aaagttggtg tcggtcaggc acatagtaag ataattttaa
    59821 taggggaaca tgcggtcgtt tacggttatc ctgccatttc cctgcctctt ttggaggtgg
    59881 aggtgacctg taaggtagtt cctgcagaga gtccttggcg cctttatgag gaggatacct
    59941 tgtccatggc ggtttatgcc tcactggagt atttggatat cacagaagcc tgcattcgtt
    60001 gtgagattga ctcggctatc cctgagaaac gggggatggg ttcgtcagcg gctatcagca
    60061 tagcggccat tcgtgcggta tttgactact atcaggctga tctgcctcat gatgtactag
    60121 aaatcttggt caatcgagct gaaatgattg cccatatgaa tcctagtggt ttggatgcta
    60181 agacctgtct cagtgaccaa cctattcgct ttatcaagaa cgtaggattt acagaacttg
    60241 agatggattt atccgcctat ttggtgattg ccgatacggg tgtttatggt catactcgtg
    60301 aagccatcca agtggttcaa aataagggca aggatgccct accgtttttg catgccttgg
    60361 gagaattaac ccagcaagca gaagttgcga tttcacaaaa agatgctgaa ggactgggac
    60421 aaatcctcag tcaagcgcat ttacatttaa aagaaattgg agtcagtagc cctgaggcag
    60481 actttttggt tgaaacgact cttagccatg gtgctctggg tgccaagatg agcggtggtg
    60541 ggctaggagg ttgtatcata gccttggtaa ccaatttgac acacgcacaa gaactagcag
    60601 aaagattaga agagaaagga gctgttcaga catggataga gagcctgtaa cagtacgttc
    60661 ctacgcaaat attgctatta tcaaatattg gggaaagaaa aaagaaaaag agatggtgcc
    60721 tgctactagc agtatttctc taactttgga aaatatgtat acagagacga ccttgtcgcc
    60781 tttaccagcc aatgtaacag ctgacgaatt ttacatcaat ggtcagctac aaaatgaggt
    60841 cgagcatgcc aagatgagta agattattga ccgttatcgt ccagctggtg agggctttgt
    60901 ccgtatcgat actcaaaaca atatgcctac tgcagcgggc ctgtcctcaa gttctagtgg
    60961 tttgtccgcc ctggtcaagg cttgtaatgc ttatttcaag cttggattgg atagaagtca
    61021 gttggcacag gaagccaaat ttgcctcagg ctcttcttct cggagttttt atggaccact
    61081 aggagcctgg gataaggata gtggagaaat ttaccctgta gagacagact tgaaactagc
    61141 tatgattatg ttggtgctag aggacaagaa aaaaccaatc tctagccgtg acgggatgaa
    61201 actttgtgtg gaaacctcga cgacttttga cgactgggtt cgtcagtctg agaaggacta
    61261 tcaggatatg ctgatttatc tcaaggaaaa tgattttgcc aagattggag aattaacgga
    61321 gaaaaatgcc ctggctatgc atgctacgac aaagactgct agtccagcct tttcttatct
    61381 gacggatgcc tcttatgagg ctatggactt tgttcgccag cttcgtgaga aaggagaggc
    61441 ctgctacttt accatggatg ctggtcccaa tgttaaggtc ttctgtcagg agaaagactt
    61501 ggagcattta tcagaaattt tcggtcatcg ttatcgcttg attgtgtcaa aaacaaagga
    61561 tttgagtcaa gatgattgct gttaaaactt gcggaaaact ctattgggca ggtgaatatg
    61621 ctattttaga gccagggcag ttagctttga taaaggatat tcccatctat atgagggctg
    61681 agattgcttt ttctgacagc taccgtatct attcagatat gtttgatttc gcagtggact
    61741 taaggcctaa tcctgactac agcttgattc aagaaacgat tgctttgatg ggagacttcc
    61801 tcgctgttcg tggtcagaat ttaagacctt tttctctaga aatctgtggc aaaatggaac
    61861 gagaagggaa aaagtttggt ctaggttcta gtggcagcgt cgttgtcttg gttgtcaagg
    61921 ctttactggc tctgtatgat gtttctgttg atcaggagct cttgttcaag ctgactagcg
    61981 ctgtcttgct caagcgagga gacaatggtt ccatgggcga ccttgcctgt attgtggcag
    62041 aggatttggt tctctaccag tcatttgatc gccagaaggt ggctgcttgg ttagaagaag
    62101 aaaacttggc gacagttctg gagcgtgatt ggggcttttc aatttcacaa gtgaaaccaa
    62161 ctttagaatg tgatttctta gtgggatgga ccaaggaagt ggctgtatcg agtcacatgg
    62221 tccagcaaat caagcaaaat atcaatcaaa attttttaag ttcctcaaaa gaaacggtgg
    62281 tttctttggt cgaagccttg gaacagggga aatcagaaaa gattatcgag caagtagaag
    62341 tagccagcaa gcttttagaa ggcttgagta cagatattta cacgcctttg cttagacagt
    62401 tgaaagaagc cagtcaagat ttgcaggccg ttgccaagag tagtggtgct ggtggtggtg
    62461 actgtggcat cgccctgagt tttgatgcgc aatcaaccaa aaccttaaaa aatcgttggg
    62521 ccgatctggg gattgagctc ttatatcaag aaaggatagg acatgacgac aaatcgtaag
    62581 gacgagcata tcctctatgc ccttgagcag aaaagttcct ataatagctt tgatgaggtg
    62641 gagctgattc attcttcctt gcctctttac aatctggatg aaatcgatct ttcgacagag
    62701 tttgctggtc gaaagtggga ctttcctttt tatatcaatg ccatgactgg tggaagtaat
    62761 aagggaagag aaatcaatca aaagctggct caggtggcgg aatcctgtgg tattttattt
    62821 gtaacgggtt cttatagcgc agccctcaaa aatccaacgg atgattcttt ttctgtcaag
    62881 tctagtcatc ccaatctcct ccttggaacc aatattggat tggacaagcc tgtcgagtta
    62941 ggacttcaga ctgtagaaga gatgaatcct gttctattgc aagtgcatgt caatgtcatg
    63001 caggaattac tcatgcccga gggagaaagg aagtttagaa gctggcaatc gcatctagca
    63061 gattatagca agcaaattcc cgttcctatt gtcctcaagg aagtgggctt tggaatggat
    63121 gccaagacaa tcgaaagagc ctatgaattc ggtgttcgta cagtggacct atcgggtcgt
    63181 ggtggcacca gctttgccta tatcgaaaac cgtcgtagtg gccagcgtga ttacctcaat
    63241 caatggggtc agtctaccat gcaggccctt ctcaatgccc aagaatggaa agataaggtc
    63301 gaactcttgg ttagtggagg ggttcggaat ccgctggata tgattaagtg cttggttttt
    63361 ggtgctaagg ctgtgggatt gtcacgaacc gttctggaat tggttgaaac ctacacagtt
    63421 gaagaagtga ttggcattgt ccaaggctgg aaagcagacc tacgcttgat tatgtgttcc
    63481 cttaactgtg ccaccatagc agatctacaa aaagtagact atcttcttta tggaaaatta
    63541 aaagaagcaa aggatcagat gaaaaaggcg taaccagcgc cttttttcca tcctcagact
    63601 gaggtgactt ttttgaattg tgataaaata gaagggagag gatgaaccta tgagaaaatt
    63661 taaaatcttt ttatttatcg aagcctgtct tctgacagga gctctgattt tgatggtatc
    63721 agagcatttt tcgcgttttc tgctgatact attcctcttt ttgcttttga ttcgctacta
    63781 cactggtaaa gagggaaata atcttctttt agtagcggca accattctct tctttttcat
    63841 cgttatgctc aatccttttg tgattctagc tatttttgtt gcggttatct atagcctctt
    63901 tcttctttac ccgatgatga accaggaaaa agagcagacc aatttggttt ttgaagaggt
    63961 cgtgacggtt aagaaggaga aaaatcgttg gtttggaaat cttcatcatt tttcaagcta
    64021 ccagacttgc caattcgatg atatcaatct ctttcgcttc atgggcaagg acactattca
    64081 tctggagagg gtcatcttaa ccaatcatga caatgtcatt atcctcagaa agatggtagg
    64141 aacgaccaaa atcatcgtac ctgtagatgt ggaagtcagt ctcagcgtta actgtctcta
    64201 tggggatttg acttttttca accagcccaa gcgagccctc cgcaatgaac actatcatca
    64261 agaaacaaaa gactatctca agagtaacaa gagtgtcaag attttcttga ccactatgat
    64321 tggtgatgtg gaggtggtta gaggatgaaa aaacaagcct atgtcattat tgctctcacc
    64381 tccttcctat ttgtcttttt tttctcccac agcttgctgg aaatacttga ttttgactgg
    64441 tctatctttt tgcacgatgt cgaaaaaaca gaaaaatttg tctttttatt gttggttttc
    64501 agcatgtcca tgacctgtct cttagccctg ttttggcgag ggatcgaaga gctttctcta
    64561 agaaaaatgc aggctaatct caagcgttta ttagcagggc aagaagtggt tcaggttgca
    64621 gatccagatt tggatgccag tttcaagtcc ttatcaggta aacttaacct tttgacagag
    64681 actcttcaaa aagctgaaaa tcagagcctt gctcaggaag aggaaatcat cgagaaggaa
    64741 cggaagcgaa ttgctcggga tttgcacgat acagtcagtc aggagttgtt tgcggcccac
    64801 atgattttat cgggtatcag tcagcaggct ttgaaattgg atagagaaaa gatgcagatc
    64861 cagttgcaga gtgtcacagc tattttagaa actgcccaga aggatttgcg ggttttgctc
    64921 ttgcatttgc gaccagttga actggagcag aagagcttga tagaagggat tcagattctc
    64981 ttaaaagagc ttgaggacaa gagtgatctt agggttagtc tcaagcagaa tatgacgaaa
    65041 ttgcctaaga aaatcgagga gcatatcttc cgtatcctgc aagagttgat tagcaatacc
    65101 ctccgccatg cccaggcatc ttgcctagat gtctacctct atcagacaga tgttgaattg
    65161 caactgaagg tggtggacaa tgggattggt ttccagttag ggagcttaga cgacttgagt
    65221 tatggactgc gaaatatcaa ggagcgggtt gaagatatgg cagggacggt tcagttatta
    65281 acagctccca agcaagggct ggcagttgat atccgtattc ccctgttaga taaggaatga
    65341 taaaggagta aagatgaaaa ttttactagt agatgaccat gaaatggtcc gtttgggttt
    65401 gaaaagctac tttgacctcc aagacgatgt agaagttgtg ggtgaggcgt ccaacgggtc
    65461 tcaagggatt gacttggcct tggaactgcg tccagatgtc attgtcatgg atattgtcat
    65521 gcctgagatg aatggaattg acgcgacctt agcaatcctt aaagaatggc ctgaagccaa
    65581 gattttgatt gtgacctctt atttggacaa tgaaaaaatc atgccagtct tagatgctgg
    65641 tgccaaaggc tatatgctca agacttctag tgcagatgaa ttgcttcatg ccgtcagtaa
    65701 ggtagctgct ggcgagctgg ccattgagca agaggttagc aagaaggttg aataccaccg
    65761 caatcatatg gaacttcatg aagaattgac tgcgcgtgag cgagatgttc tccaactcat
    65821 cgccaagggc tacgaaaatc agcgcatcgc agatgacctc tttatctctc tcaagacggt
    65881 caagacccac gtgtccaata ttcttgccaa acttgaagtc agcgatcgta cccaggcggc
    65941 tgtctatgcc tttcagcacc atttggtggg gcaagaggag ttttagatga gtttagcaga
    66001 tttacttgag gagctagaag cagcaaaaga ctctaaaaaa gcaaggtcca tggaagccta
    66061 tatgcgccat caattttctt ttctaggtat tgcggtgcct gaaagaaata aactctataa
    66121 aaatattttc cagaagcgaa aaaaacaaag attatcgatt gggattttgc agacacttgc
    66181 tgggaaaagg atcctagaaa ataccaatat gtggctgcta actatttgaa agcaatgcag
    66241 tcttatctaa aggaaaccga tttgcctaag ctagagcagt tagtcgtgac aaaatccttg
    66301 tgggacacgg tagatatcct agatcgagta gtagggagtt tggtgtatga acaccctgaa
    66361 ctagaagaaa taatcttaat actcttcgaa aatctcttca aaccacgtca gctctatctg
    66421 caacctcaaa acagtgtttt gagcaatctg cggctagctt cctagtttgc tctttgattt
    66481 tcattgagta taaaatggag cctatcagat aatatctggc tgagacgtgt cgctattgac
    66541 caccagttgt taagaaaaga gaagaccaat actcaattaa tggaaaagat tctccttcat
    66601 aacttgaacc aaacagaatt ttttatcaat aaagccattg gctggactct gcgagactac
    66661 tccaaaacga atcccacttg ggtaacatgc tttattgaga aaaacaagga aagaatggct
    66721 gaacttagta tcaaagaagc aagcaagtac ctctagcgtg attgaaaagc gcagtcatta
    66781 attgaaaagt ttacctgttt atgtgataat ggagggtatt taaagaaggt ggtagatttc
    66841 ttgattctat agtagattga gaaatttaga atagtacgct ataattacat taggaggata
    66901 cgataatgaa gaaaactgtt tataaaaaat tgggtatttc aattattgcg agtactttat
    66961 tggctagcca gttatcgaca gtatctgctt tgagtgttat ttctagtaca ggtgaagaat
    67021 atgaggtaag tgagacacta gaaaaaggtc cagagtctaa tgattcttca ttatctgaga
    67081 tttcaccaac gtatggttca tactaccaaa agcaatcaga agtattatcg gtaatgatga
    67141 tttgattaaa attgataata ctttacagta tccgtattcg acttcagcta tggttttatc
    67201 taagtattat ggagtagccg atggaatgaa tgtagaaggg aggggaagtg cgaattttat
    67261 taaagataat gtgttaatta cagcggctca caactactac agacatgact atgggaaaga
    67321 agcggatgat atttatgttc ttccggctgt tagtccaagt caagaactat ttggaaagat
    67381 caaagtaaag gaagttcgtt atttgaagga atttagaaat ttaaattcta agaatgcaag
    67441 ggaatatgac ttggctttat taattctaga agagcccatt ggtgcaaaat tagggacttt
    67501 gggtcttcct actagtcaaa aaaatttgac aggaataact gtgactatca caggctatct
    67561 atcatataat tttaaaattc atcaaatgta tacagataaa aaacaagttt taagtgatga
    67621 tggcatgttc ttggattacc aagttgatac tttagagggg tctagtggat ctgcagttta
    67681 tgatgctagt caccgcgtag taggagtgca tactttagga gatggagcta atcaaattaa
    67741 cagtgcagtt aaattaaatg aacgaaattt gccatttatt tattcggttc ttaaaggtta
    67801 ctctcttgaa ggatggtgaa tgggttaggt aatgaaggct aattgtaaac tgtgatggat
    67861 acttaacttt gtataatagg tggataaaag tctttaaaat aggaaaaaac gcatattatt
    67921 aggtgtttaa aaaccttgat aatatgcgtt ttataatgga aagatttctt caatttcgtc
    67981 ttgtatagta gattgaaact ataatagtac acctctactt ctaaaacatt gttagaaatt
    68041 gatttgactg tcctgatcga tttgtcctgt tcttatttcg ttttactata atgtaatcgt
    68101 ccaataacga agtgtttttg gatagtccga aaagtttagc ttcatataga gtaattggta
    68161 ttagtgatag agtgttagaa attttaaaag aatatcttct tttagaagaa ggtgattata
    68221 tatttacaaa taatggttct cccttaatga taacttgttt caattacttt ttgaaaaaca
    68281 ggtttaggaa aagtgaaatt aagaaagatg attttgtatt gactgctcat gtttttagat
    68341 attcgcatat aagtttgctt gctgaattgg aagtacctat aacagcgata atggatcgtg
    68401 tagattatac taatgaaaca aagattttaa gtgtttatac tcatgttact gagaagatga
    68461 agtcaaatat aacttaaaaa ttagataaat tagttttgga aaatgactaa ccaaaagata
    68521 tccaaagtag tctaaaattg tctatacttt atgagtgttt tagttaggaa aaaggcttgt
    68581 tgtctataat tgtctgcatt agtctagatt ttatttatag aaaatgttat aatagactgt
    68641 atttaaaaaa ttttaaggag aaatgacaga atgtctgtat catttgaaaa caaagaaaca
    68701 aaccgtggtg tcttgacttt cactatctct caagaccaaa tcaaaccaga attggaccgt
    68761 gtcttcaagt cagtgaagaa atctcttaat gttccaggtt tccgtaaagg tcaccttcca
    68821 cgtcctatct tcgataaaaa atttggtgaa gaatcacttt accaagacgt tatgaacgct
    68881 cttttgccaa acgcttatga agcagctgta aaagaagctg gtcttgaagt ggttgcccaa
    68941 ccaaaaattg acgtaacttc aatggaaaaa ggtcaagact gggttatcgc tgctgaagtt
    69001 gttacaaaac ctgaagtaaa attgggtgac tacaaaaacc ttgaagtatc agttgatgta
    69061 gaaaaagaag taactgacgc tgatgtcgaa gagcgtatcg aacgcgaacg caacaacctg
    69121 gctgaattgg ttatcaagga agctgctgct gaagacggcg acactgttgt gatcgacttc
    69181 gttggttcta tcgacggtgt tgaatttgac ggtggaaaag gtgaaaactt ctcacttgga
    69241 cttggttcag gtcaattcat ccctggtttc gaagaccaat tggtaggtca ctcagctggc
    69301 gaaaccgttg atgttatcgt aacattccca gaagactacc aagcagaaga ccttgcaggt
    69361 aaagaagcta aattcgtgac aactatccac gaagtaaaag ctaaagaagt tccagctctt
    69421 gacgatgaac ttgcaaaaga cattgatgaa gaagttgaaa cacttgctga cttgaaagaa
    69481 aaataccgca aagaattggc tgctgctaaa gaagaagctt acaaagatgc agttgaaggt
    69541 gcagcaattg atacagctgt agaaaatgct gaaatcgtag aacttccaga agaaatgatc
    69601 cacgaagaag ttcaccgttc agtaaatgaa ttccttggga acttgcaacg tcaagggatc
    69661 aaccctgaca tgtacttcca aattactgga actactcaag aagaccttca caaccaatac
    69721 caagcagaag ctgagtcacg tactaagact aaccttgtta tcgaagcagt tgccaaagct
    69781 gaaggatttg atgcttcaga agaagaaatc caaaaagaag ttgagcaatt ggcagcagac
    69841 tacaacatgg aagttgcaca agttcaaaac ttgctttcag ctgacatgtt gaaacatgat
    69901 atcacaatca aaaaagctgt tgaattgatt acaagcacag caacagtaaa ataatcttaa
    69961 taaacagaaa acccaccaat tcaggtgggt tttctgatgc actattttcc aaaaatctct
    70021 ttgaggtctg tgtctgtaat cccaatcatg gctgggatgc ggtcccagtt ttcttcggtt
    70081 aggatgtagg attgttcaga ggcacttgat gtgactgttt cagagacagc ttgttgcttt
    70141 tcttcaacat tcttcagtag atcactgaag cgttcaacca gataggtttt tcgggcagtt
    70201 ccgatgtgtt gggtagcatg gtcgaaggct tgtaattcgc ctagtaagat gagtttgctt
    70261 ttggcacgtg taatggctgt gtagatgaga tttcgctcca gcatacgtcg gctagcacta
    70321 gtaatcggta ggatgacaac tgggaactca cttccctgag acttatgaat actcatggca
    70381 taggccaagc gaatcttgta ccattcgtta cgggggtaag agacttcatt accatcaaaa
    70441 tcaatgacaa tctcgtcttg tttcgattcg gtgtatttac caggaatcag gtctgtgata
    70501 gctcctaaat ccccattaaa gacattgatt tcagtatcgt taaccaaatg aatgaccttg
    70561 tctcccttac gatagtggca ctgaggagct tcaaaactga gttgatcttt ttgtggggga
    70621 ttgagcaggt cttgcatgag ctgattgata gcatcaatcc ctgccgtccc tcggtacata
    70681 ggagccagaa cttggatatc acgggcagga ataccatttc tgagggcggc acctaagatt
    70741 ttttcaatgg tggcaggaat atggccacta gcaatttcaa agtaggaacg gtcagctttt
    70801 ttttgggtga aatcagctgg caagatgccc tgtcgaatct gactagctag ggtgacgatg
    70861 gttgattctt cgctttgtcg ataaattttt tccaagcgag tctgaggaat caaaggaata
    70921 tgaagcagat ccgctagaac ctgtccagga ctgacagaag gtagctgatc actgtcacct
    70981 acgatgagga tcttactgtt agaagagata ttggagaaga gttgattggc cagccaagta
    71041 tccaccatag agaattcatc cacgatgata aagtcagtat ctaggtaatc ttccagatga
    71101 ctggtatcat cgtcacctgt cattcccaag tggcggtgta tggtcgcgct aggcaagcct
    71161 gtcaattcat tcatgcgacg agcggctcgt ccagttggag cagcaagaag aatgggcagg
    71221 ttgcttttct tcctgaggtc aagtccctct aacagggcgt aaacagcgat gatcccattg
    71281 ataacagttg tcttaccagt accaggtcca cctgtcagga taaagacctt attctggata
    71341 gcatcacaga tagcctgttt ttgaatgtta tcatactcaa ttcccagctc ttcctcgata
    71401 gtagtgatat gtttttgaat ggtttctaaa tcatgactct tctgttttcc tttttcaagg
    71461 atacgaacca agtgactgcg gatgccttcc tcagcgaaaa agaggctgtt gtcaaagatc
    71521 ttggtatcaa tctgctgaac cttgtcttct tcgatcaggt aggagagctc ttgggcaact
    71581 tggctggggt ctagttccac gggacgggaa gactcaagga gagtaagggt ttgttccagc
    71641 aaatcccgta cttcaacata ggtgtcccct gtttccatac aggcctgaaa aagactgtga
    71701 actagaccgg cgcggaagcg ttcaggagcc tgactttcga tgcctagttc ctcagctagt
    71761 tggtcagcaa tggtaaagcc caaacccttg atatcctcaa ccagctggta gggataattt
    71821 tcaaccacat caagggtttc ttccttgtaa aagtcttgaa tctgaaatgc tagtttgttg
    71881 ggaatgccgt agttggctag tttggccaaa atcatctccg ttccgtagtt gagacggaga
    71941 gtggagacga aagcctcgcg atttttggca gagagtccta cgatgccttc taacttttct
    72001 gggtgttgca aaatttcgtc aatggtattt tcgccatagg tatccacgat tttctgagct
    72061 gtcttgagac caatcccctt gaaatggcta cttgaaaagt acttgaccaa gcccttacta
    72121 gttggttttg cgcgatcata acgactgatt tgcagttgtt ctccatactt ggagtgctgg
    72181 acaatttgcc cccaaaaagt atagtcttcg ccctcaatta catcagccat ggttcctgtg
    72241 acaatgattt caaaatcatc aaaatcctct gcgtccgtat cgtcgatttc taggaggagg
    72301 atgcgataaa aattgctggg attttcaaaa ataatccgtt caatagttcc tgaaaaataa
    72361 acttccataa aattcctttg catgaatagg tgagagttga ggtgtttctg ttctggtaag
    72421 tttagatagt taccaatcat tttctcacga tagaagaaga ggctgagatt ggtgattctc
    72481 ggcctcttag gtctcttaaa atgttccgat acgggtgatt ggccagaagc ggaatttagc
    72541 ttcccctgtg atatcttttg ctttgaaggt acctacgtgg cggctgtcgc tcgaaaccaa
    72601 gcggtcatct ccgaggagaa ggtattctcc ttctggaaca gtaaagctaa agttggtgtt
    72661 gtagttgaca tcaactgtga aggcttgggc tttttgagcg atacttctaa agaaagttcc
    72721 tttatttcct tcaaagccct tgcctgagta agtgctttgg agtttgtcat ccttgaagcg
    72781 tttgatatag tctgctagat aaggctcgtc cgtttctttg tcattgatgt agagtttatc
    72841 attttcgtaa cgaatggtgt cgccaggcat tccaatcacg cgcttgacga tgtccttatt
    72901 gccatcttcc tcatgggcca ccacgatatc aaaacggtca ataggaaggt gttttacaac
    72961 gaagagaatt tcgccatccg ctagggtcgg atccatggaa tgtccttcta cgcgaacatt
    73021 gctccaaaaa aagatacgac ttaaagctag taatgacaga attaggagga acagtcccca
    73081 ctctttcaag aaatttttaa atgaattcat aacttacctt tctaagcgtt ttttcgcttt
    73141 ttcagtgttt ttaaagtgca atttggcgca gaagttgagt ccctgcatac cataggcttg
    73201 caaaatctgg ctagccacct tgtcagaagc cgttccagct ccacttggaa gctgataacc
    73261 cagttctcgt cccaaatttt caagattttc cagaaagaga tcacgcgcaa tgacagaaga
    73321 aactgcgaca gccaagtatt tgccctcagc cttttcttct aagctgatag gattgctgaa
    73381 acgattggtc tcttgtgcca agtacttgtc ataattttta gcactggtaa aggcatcaat
    73441 cacaattttc tcaggctgaa cacctttttg aaggaggaga tagatagcct gattatggag
    73501 ggcaacctta accgaaacag cattgtagcg gtttccgatg acctcgttgt acttgctggg
    73561 tgagagaagg agtgcctggt gctggatttt ttccttgaga ataggagcaa tctgacggat
    73621 cttttggtcg gtcagagtct tagaatcccc cacaccgagt tttcgtaaaa agtcgtgctg
    73681 gtcaggtgtg acaaaggcag ccacaactgc aagcccacca aagtaggaac catttcccac
    73741 ctcatctgtc ccaattaaag gaagattttg tccgctggtt tgctctacag cttgatagcc
    73801 aaagaaactg gcgtattttt cagccccttc accctgaagc aagatttttc cagaagtata
    73861 gatagaaacc gttgcttgag gtagtttcaa aaagtagcgg atatagggat tcttgctagg
    73921 agccagactg gtttgatagt gttcaagaaa agcctgaata tccttttcgc ttggtgtgag
    73981 tgtgatactt gccatagttt ctattgtacc acaaaagcag taaaatttgt aaaaactgac
    74041 aaaattagcg aattttggta taatatcgtg aggtgaattt tatggcaaat ctaaatcgat
    74101 tcaaatttac attcgggaaa aaatcgttaa ccttgacaag cgaacatgat aaccttttta
    74161 tggaggaaat cgctaaggtt gcgacagaaa aataccaagc aattaaagaa caaatgccta
    74221 gcgcagatga tgaaacaatc gctcttttgt tggcagtcaa ctgtttatca actcagctca
    74281 gccgtgagat tgaatttgac gataaggagc aagagctaga agaactccgt cacaagcttg
    74341 tgacttgtaa gcaagaacag agcaagattg aggattcctt atgatttcat tccttcttct
    74401 attggtcttg gtttggggat tttatatcgg ctatcggaga ggcctgctct tacaggttta
    74461 ttacctgatt tcagccatgg catcggcttt tatggctggc cagttttata aggggcttgg
    74521 agagcaattc catttattgc tcccttatgc aaattcgcag gaaggtcagg ggactttctt
    74581 tttcccatcg gatcaactct ttcagctgga taaggtcttt tatgcaggca tcggctactt
    74641 gcttgtattt gggattgtct atagcattgg tcgtttgctt ggtcttctct tacacttgat
    74701 tcctagcaaa aaactgggtg gtaagttgtt ccaagtttca gcaggtatct tgtccatgtt
    74761 ggtgacctta tttgtcttgc aaatggcctt gacaatcttg gcgaccatcc ccatggcagt
    74821 tatacaaaat cctcttgaaa agagtatcgt cgcaaaacac atcatccaga gcataccgat
    74881 aacaaccagt tggctcaaac aaatctgggt gacaaattta atcggataaa aagggcagga
    74941 gttttcctag ccctttgttt acagatttga ctcgaatcta tcagaatgta aaaagctacc
    75001 acacctagac attcaaagac aaggaaataa agatgaataa gaaaatatta gaaacattag
    75061 agttcgataa ggtcaaggcc ttgtttgagc ctcatttgtt gaccgagcag ggcttggagc
    75121 aattgagaca actggctccg actgccaaag cagataaaat caaacaggct tttgctgaga
    75181 tgaaggaaat gcaggctctt ttcgtcgagc aaccgcattt tactattctc tcaactaagg
    75241 aaattgcagg agtctgcaag aggttggaga tgggagcgga tctcaatatc gaggagttcc
    75301 tactcttgaa acgcgtgctt cttgccagcc gagaacttca aagtttttac gccaatctgg
    75361 aaaatgtcag cttggaagaa ttagcccttt ggtttgagaa attacatgat tttccgcaat
    75421 tacaaggaaa tcttcaggcc tttaatgatg cgggtttcat tgaaaatttt gccagtgaag
    75481 aattggcgcg aatccgtcga aaaatacatg atagcgagag tcaggtacgc gatgttttac
    75541 aagacttgct caagcaaaaa gcgcagatgt tgacagaagg aattgttgct agcagaaatg
    75601 gccgtcaggt tttaccagtc aaaaacacct accgcaataa gattgcaggt gtcgttcatg
    75661 atatttctgc tagtggaaac accgtctata tcgaaccacg tgaggtagtc aaactgagcg
    75721 aagaaattgc tagtctgcga gcagatgagc gctatgaaat gcttcgcatt ctccaagaaa
    75781 tttctgagcg tgtccgccct catgcgactg agattgctaa tgacgcttgg attatcggtc
    75841 atctggactt gattcgtgcc aaggttcgat ttatccaaga aagacaagca gtcgtgcctc
    75901 agctgtcaga aaatcaagag attcaactgc tccatgtctg ccatcctttg gtcaaaaatg
    75961 ccgtcgcaaa tgatgtccat tttggtcaag atttaacagc tattgtcatt acaggtccca
    76021 atacaggtgg gaagaccatc atgctcaaaa ctctgggctt gacacaggtc atggcccagt
    76081 caggattgcc gattttagca gacaggggaa gtcgtgttgg tatttttgaa gaaatctttg
    76141 ctgatattgg agatgagcag tctattgagc agagcttgtc taccttctct agccatatga
    76201 ccaatatcgt ggatattctt ggcaaggtca accaacattc actcttactt ttggatgagt
    76261 tgggggctgg tactgatccc caagagggag cagcccttgc catggctatt ctggaggacc
    76321 ttcgcctgcg tcaaatcaag accatggcga cgacccacta tccagaactc aaggcctacg
    76381 gtattgagac agcctttgtg caaaatgcca gtatggagtt tgatactgca actcttcgcc
    76441 cgacctatcg ctttatgcag ggtgttcctg gccgaagtaa tgcctttgaa attgccaaac
    76501 gtctaggcct atctgaagtt atcgtaggag atgccagtca gcagatcgat caggacaatg
    76561 acgtcaatcg tatcattgag caattagaag agcagacgct ggaaagccgc aaacgcttgg
    76621 acaatatccg tgaggtggag caagaaaatc tcaagatgaa ccgtgcgcta aaaaaactct
    76681 acaacgagct taatcgtgaa aaggaaaccg agcttaacaa ggcgcgtgaa caggctgctg
    76741 agattgtgga tatggcccta agtgaaagtg accagattct caaaaatctc cacagtaaat
    76801 cccaactcaa gccccacgaa atcattgaag ccaaggccaa gttgaaaaaa ttggctcctg
    76861 aaaaagtgga cttgtctaaa aacaaggtcc ttcaaaaggc caagaaaaaa cgagctccaa
    76921 aggtgggaga tgatatcgtg gttctcagtt atggtcagcg tggtaccttg accagtcaac
    76981 tcaaggacgg ccgctgggaa gcccaagttg gcttgattaa gatgaccttg gaagagaaag
    77041 agtttgatct tgttcaagcc cagcaagaaa aaccagtcaa gaagaagcag gtcaatgttg
    77101 tgaaacgaac ttctgggcga ggacctcaag ctagactgga tcttcgaggc aagcgctatg
    77161 aagaagccat gaatgagcta gatatcttca tcgaccaagc cttgcttaac aatatggctc
    77221 aagttgatat catccatggt atcggaacag gagtcatccg tgaaggagtt accaaatact
    77281 tgcaaagaaa caaacatgtc aagagtttcg gctatgcccc acaaaatgct ggaggcagtg
    77341 gtgcgactat tgtcactttt aaaggatagc agtattctgg actttataaa gtaaaaactg
    77401 ttgaactaat ttttactaat aaacacattg acaaaagcca acattttttg taaaattaga
    77461 atcaattaaa taccaacacc gaatgaagtt taatagaagt ggggaatcgt ttgattttcc
    77521 atgactgtaa atggacggaa ctctggagag accgtaaagg caccgaaggg gcaaggcagg
    77581 caactgctca aactctcagg taaaaggaca gagctaggat agaccgcttt ttagcattta
    77641 tctaagcatt ccagagtaca tgtatcttgc atgtgctctt tcttttgggg ttgaaacgat
    77701 aggagaagga aatgttagaa ttgcttaaat caatcgatgc ttttgcttgg ggaccgcccc
    77761 tcttgatttt attggtcgga acagggattt acctaactat tcggctagga ctcttgcagg
    77821 ttttgcgtct gcccaaggct tttcagctta tttttatcca ggataaggga catggtgatg
    77881 tatccagttt tgcagctctg tgtacagcct tggcatcaac tgttggaaca ggaaatatca
    77941 taggagttgc gacggctatc aaggttggtg gaccaggagc tctattttgg atgtggatgg
    78001 cggctttctt tggaatggct accaagtatg cggaaggact cttggccatc aaataccgca
    78061 ccaaggacga ccatggtgca gtagcgggag gtcccatgca ttatatcctt ctagggatgg
    78121 gagaaaagtg gcgaccactt gctgttttgt ttgcagtagc aggagtattg gttgctctct
    78181 tgggaatcgg aaccttcacc caagtcaact cgattgcaga atctatccaa aatacaacga
    78241 cgatttcgcc agccatcaca gctctcgtct tgtctgtctt tgtagcgatt gcagtctttg
    78301 gtggactcaa gtctatttct aaggtttcaa ctactgttgt tccttttatg gccatcattt
    78361 atatcttagg aactcttaca gttattttct ttaatattgg aaaaatccct ggcacaatcg
    78421 ctttagtctt tacctcagct tttagtcccc ttgctgcggt aggtggattt gctggtgcta
    78481 gcgttcggat ggctattcaa aatggtgtgg cgcgtggtgt gttctcaaac gaatctggtc
    78541 tgggttctgc tcctattgca gctgccaaga caaatgaacc agtagagcaa ggtttgattt
    78601 ccatgacagg aacctttatt gataccctca tcatttgtac tctaactggt ttgaccatct
    78661 tggtaactgg agtttggagt ggtgacttga atggggttgc cttgactcag tcagctttct
    78721 caacagtctt ttcacacttt gggcctgccc tcttgaccat cttccttgta ctttttgcct
    78781 ttacaacgat tctaggttgg aactattacg gagaacgctg ttttgagttc ctctttgggg
    78841 ttcgctttat ctggctctac cgtgtggttt ttgtgctcat ggtcttgtta ggaggattta
    78901 tcgagttgga tatggtctgg attatcgcag atatcgttaa cgccttgatg gctctgccaa
    78961 acttgattgc cctcttggtc ttgtcgccag tcgttattgc tgaaactaaa aagtattttg
    79021 acaaataatg gaatcacaca gctcgtgtga tttttttgcc tataaataat ttttatcagc
    79081 ctgatatata atatatatta tgcaagtgat tggaagtgtg ataaactaat ataacaacga
    79141 aaatcttatg agagaataaa gctttatctt agataaactt aggaatcagg attttataag
    79201 attttccaat aatattagtg tcaataataa gaaaagaggt atcttatgac aacatttact
    79261 atccatacag tagagtcagc accagcagaa gtgaaagaaa ttcttgaaac agtagaaaaa
    79321 gacaacaatg gctatattcc caacctaatc ggtctcttgg ccaatgcccc gactgtttta
    79381 gaagcctacc aaattgtctc atctatccac cgtcgcaaca gcctgacacc cgttgagcgt
    79441 gaagtggtgc aaatcacggc agccgtgacc aatggttgtg ccttctgtgt cgcaggtcac
    79501 acagcctttt ccatcaaaca aatccagatg aatgatgact tgattcaagc tcttcgcaat
    79561 cgtactccaa ttgaaacaga tcctaaattg gataccctag ctaagtttac cttggcagtt
    79621 atcaatacca agggtcgtgt aggagatgaa gccttgtctg agtttttaga agctggctac
    79681 actcaacaaa atgccttgga tgtggttttt ggtgtcagcc tagcaatcct ctgtaactat
    79741 gccaacaact tagctaatac accaattaat ccagaattgc aaccttatgc ctaattcata
    79801 tctgagtaaa atgaagtctg aaataagcgg acttcgtttt tttaaatcct catttaagcg
    79861 cttttatgtt atactgaaac taacatgatt attggaggtt aggatgaaaa aactcccctt
    79921 agtattttca ggttgtttgc taggtttggc aggagctgga aatcttattt tagatacgtt
    79981 gccggttcta tcccatcttt ttagtctgac tggtttggtt ttatggattt actttctaat
    80041 tctgcatctc tttaattgga aagaaaccaa gcaagaattg accaagcccc ctcttttgtc
    80101 aggaatggca acctttccta tggctgggat gattttatcg acctatgtct ttcgcgtatt
    80161 ctcttatctt cctttggtag cacaagggat ttggtggttt tcatttctct tggatttgac
    80221 cttgattgct ggttttacca tcaagtttgc ttgtccaggg cggagggttc atgccactcc
    80281 aagctggacg gttctctatg tggggatagc agtggctgcc ttgacctatc ctctggtagg
    80341 tattatcgaa attgcctatg cgaccttgag ttttggtttt ctcttgacct tctatctcta
    80401 tccccttatt tatagcgatt taaagaaaca tccactccca ctagccttgc ttggacaaga
    80461 aggaatctac tgtgctcctt tctctctact cttggcttct ctagttcgag taggaggaac
    80521 cagcctgccg acttgggtct tgattgtcat gattttggct tctcaatcct tctttttctt
    80581 tgttttaact cgtctgccca acattttaaa acaaggtttt caaccagcct tctcagccct
    80641 caccttccca accattatca cagcgacctc gctcaagatg actcagggaa ttttgaaact
    80701 tccatttctg gattacctgg tattggctga aaccattata tgcctaacta ttttattctt
    80761 tgtactaggt gcttatctga tttggttacg aaaaaaggtc tagctagaaa tagctaaacc
    80821 ttatttttta tggtttgatg acttcagctc cacccatgta tggacgaagt gcttctggga
    80881 tggtcacaga accatcttca ttttggtaat tttcaagaat tgcagccact gtacgtccaa
    80941 ctgcaagtcc agaaccgttc aaggtatgaa ggagtttcac cttgccatct gcttcatcac
    81001 ggtaacggat ttgggcacga cgggcttgga aatcttctgt gtttgaacag cttgagattt
    81061 cacggtaatt gttttgtgct ggaatccaca cttccaagtc gtaagtcttc gcagctgaga
    81121 agcccatatc tccagtagag agagcaacga cacggtatgg aaggttgagt ttttgaagaa
    81181 tgttttcagc gttggctgtc attttttcca attcttcgta agattcttct ggtttggcaa
    81241 atttgaccat ttcaaccttg tggaattggt gcaaacggat caagccacgc gtatcacgac
    81301 cggcagaacc agcctcagaa cggaatgacg gactcatagc agtgaagtag attggaagat
    81361 ctttgccgtc taagatttca tcacggtagt agtttgtcag aggaacttca gcagttggaa
    81421 tcaagacaaa gttggtatcg ctgagttcaa aagtatcttc cttaaatttt ggatactgac
    81481 cagtaccaaa catagaatca tggttgacta tgtaaggtgt gatgacttca gtatagcctt
    81541 cttttccatg ttcatccaac ataaagttgt agatagcacg ttccaaacga gcaccgaggc
    81601 ctttatagaa gaggaagcga gcgcctgtta ccttaccacc gcgttcccag tcaaggatac
    81661 caaggtcttc accgagatcc cagtgagctt taggttcgaa gtcaaactcg cgtggagtac
    81721 cccaacggcg aacttccaca ttgtcgtctt cgtcagcccc aacaggaacg ctgtcagctg
    81781 ggatatttgg aagagtcgtt gtaaattctg tcaatttagc atcgatttct gccaattcag
    81841 catccaaggc tttaacctca gcagatagat tttgcatggc agcaatcttg tcatctgtat
    81901 tttccttgtt gcgcttagct tgggcaatct cagcagaaac tgtgttacgt tctgctttga
    81961 gagtttcaac cttgaccaag atgttacgac gtttagcatc gatttctttc atttcattca
    82021 agacagcagc atctacacca cgtgtagcta atttttctgc gacagcttca aaatctgtac
    82081 gaatacgttt gatatctaac ataagaactc ctttatgaaa aaagcacgcc tgacaaaacg
    82141 ttggagtggc agggccacgg ttccatccaa cttcacaggt gtgcacttga ttgtgtatgt
    82201 aattgttact aacggtagaa tttcacctat ccctcctatc tgctcgcagt acccgcagac
    82261 tttctgaaag aagaagataa cctacttatc cgttgctatg attatactaa agtttctact
    82321 tttttgcaaa tagattttta aatttttggc taattgtctg aatcagggtc ggaagtttga
    82381 cgaccttgtc attgcctagt ttttcgcgtg caattttgag aatggcacct gagtcttttg
    82441 aagcaaagag gaattttcct ttgtctgtaa agacttcgaa gtggcggctg attttgcatc
    82501 cagtgacatt ggctccaatc tgattgatat ggctccaagg aatctggata aattgttcga
    82561 cattgacatc tgggtaaaat tccaaagcct gatctccgac aaggaatttc ccaactttcc
    82621 cagcgataga gaggtaggaa gtgcctgtcg tactgaggag tactgttttg ttaagtgatt
    82681 gagccatgct tagtcttcct tactttctcc aaaaaaggca ttgtagaggg ctttaattgc
    82741 tgctttctct tggtctttat tgacaacaaa cataatagaa acttcactag aaccttgaga
    82801 catcatctgg atgttgattt tgttttcaga tagagcgcgt gtcgcagtag cagtcactcc
    82861 gatatggctc ttcatttttt caccaacaat cataatgata gaaaggtcgt gttcgatttc
    82921 tgcatgatct actttagcct tttgaaccaa ctgacgcagg atttcttctt ccttgatggg
    82981 agttagttgg cgagaacgga gaatgataga aagatcgtcg atacctgttg gcatatgttc
    83041 ccaaccgatg ttaagttctt ccaggatttg cagaaccttg cggccaaatc caacctcacg
    83101 gttcatgagg tatttcgaca tgttaatgct gacaaagcct gagtcaccag caattcccac
    83161 aactggaaat tcatcattac tgtgttttag aacgatacga gtacctggat ggtcagggtt
    83221 gttggtattc ttgataacca gaggaatttt tccacggtag gcaggaagaa gagcctcgtc
    83281 atgaaggact gagaagcctg cataggccaa ctcgcgcatt tcacggtagg tcaactcagg
    83341 aatcgagtgt ggttggtgga taataccagg gtgagctgca aagataccat caacgtccgt
    83401 aaagttttca tagaggtcag ctttgacacc agcagcaatg atagaacctg taatatcaga
    83461 acctccacgt gagaaagtac agatttgatt ttccttagtg acaccaaaga aaccaggaat
    83521 gacaaggact tcattggtgt ttgtcaattc ttcaatcttg tcataacttg atggaatgat
    83581 gcgagcgtga ccaggttcac ttgtgaccac aatcccagct tctctagggt gcatatagcg
    83641 tgcatcgata ccattttggt taaagtaggc agcaatcaat ttggcattgt tattttcacc
    83701 ggctgctagg aaagtatcgt agagaaattc attttcttca ataggaagag tggccaaggc
    83761 gtgaatgctt ttagaaattt tttctagcac agctggtttt agtcccaatt cactaaccat
    83821 agcagcatag cggtcgataa tccagctttg gctcttgcta atatcgttac ccgcaacata
    83881 gtcgcggtag tatttaatca gggcatccgt aaccttagta tcttcagcat tgcgtttacc
    83941 aggcgcagaa acgactacaa aacgacgctc tgaatcgctt ttgacgatgt ttaaaacttt
    84001 ttctaattga ctagcagagg caagagaact acctccaaat ttaacaactt tcataagaac
    84061 tcctaaagta agtattttat acgattatag cagaaagaaa ggcttttttc aatgaagaaa
    84121 ataagatgct ttctagccta aagcgagcct ttcttatcgg ctgagacact ttcagtcgat
    84181 tttttcttgc tttctgatcc taaaaaagat atactttgac agtgaaataa tttaacactc
    84241 aataaaaatc aaagagcaaa ctaagaagct agacgaagtc agctcaaaat actgttttga
    84301 ggttgcagat ggaagctgac gcggtttgaa gagattttcg aagagtataa actgcttata
    84361 aaataaaaag gagccctgat ggaacacatt atttatcagc ttgaagagga cttggcaatc
    84421 cttaccttga accgtcctga ggtcgcaaat ggttttcata ttcccatgtg tgaggagatt
    84481 ttagaagctc tgactttggc agaagaaaat ccagctgtgc attttatctt aatcaatgcc
    84541 aatggaaagg tcttctcagt tgggggagat ttggtagaga tgaagcgggc agtggatgag
    84601 gatgatattc catcattgac aaaaatcgca gagttggtca atacgatttc ttataaaatc
    84661 aagcaaatag ccaaacctgt tttaatggaa gttgacggtg ctgttgcagg tgccgcagcg
    84721 aatatggctg ttgcggcaga tttctgtttg gcgacggata aggctaagtt tatccaagcc
    84781 tttgttggtg ttggtttggc tccagatgca gggggaattc atctcttgag ccgcagtatc
    84841 ggtgtgacgc gtgctgctca attagctatg acaggagagg ctttaacggc agaaaaagcc
    84901 ctagaatggg ggttggttta ccgcgtttct gaagctgaaa aacttgaaaa gacgagagaa
    84961 cagcttctta aaaaattaag acgtgcttca agtaattcct atgctgccat taagaagttg
    85021 gtttgggaga gccaatttaa agactggcag ggttacgcta ctttagaact gaacctacag
    85081 aaatccttag ctcaaacaga ggatttcaaa gaaggagtgc gagctcattc ggagagaaga
    85141 agacctaaat ttacaggaaa ataaaaaata cttgcatcat tctttgaatt ttgatataat
    85201 tctttctgtc aaatgttttg attgtaaaag ttttttgaag aaggagggat atgaaaaatg
    85261 gactaccaac gaatcaatga atatttaaca tctatattta acaatgtcct tgtaattgag
    85321 gaagtgaact tgagaggtag tcgttttaag gatatctcca tcaaagaaat gcatacgatt
    85381 gatgtcatcg gtaaggctcc agatgtgact ccaagtcaag tgtcaaaaga gttgatggta
    85441 actcttggaa ctgttacgac aagtttgaac aatttagagc gtaagggcta cattgagcga
    85501 gttcggtcag aacaggatcg tcgtgtggtg catctgcatt tgacaaagaa gggtcacttg
    85561 attcatagac tgcataaacg cttccacaag gccatggtag aaaaaattat tgatggcatg
    85621 agcgaggaag aaattgctgt catgggtaaa ggcttgacta atctttacca atttttggag
    85681 gatttgaaat aatggctttt gcaaaaataa gtcaggttgc tcattatgtg ccagagcaag
    85741 tggttacaaa tcacgacttg gctcagatta tggataccaa tgatgagtgg atttcaagtc
    85801 gaacgggaat acgacaaagg catatttcaa gaacagaatc taccagtgat ttggctacag
    85861 aggttgctaa gaaactgatg gcaaaagctg gaataacagg agaagaactg gattttatca
    85921 tcctagctac cattactcca gattcgatga tgccctctac agctgctcgt gttcaagcta
    85981 atattggcgc taataaagcc tttgcttttg acttaaccgc ggcttgcagt ggatttgtat
    86041 ttgctctttc aactgctgaa aagtttatcg cttctggtcg ctttcaaaaa ggcttggtga
    86101 ttggtagtga aaccctctct aaggcagtcg attggtcgga tcgatcaaca gctgtgttgt
    86161 ttggagatgg tgctggtggt gtcttgttag aagctagcga gcaagagcat ttcttagctg
    86221 agagtctcaa tagcgatgga agtcgcagcg agtgtttaac ttatgggcat tcaggtttgc
    86281 attctccatt ttcagatcaa gaaagtgcag attcgttttt gaagatggat ggacgcacag
    86341 tctttgattt tgccattcga gatgtagcca agtctatcaa gcagactatt gatgaatctc
    86401 ctatagaggt gacagacttg gattatctgc tacttcatca agccaatgac cgtattttgg
    86461 ataagatggc tagaaaaatt ggtgttgacc gagccaaact tccagccaat atgatggaat
    86521 atggcaatac cagtgcagcc agtatcccga ttttactttc agagtgtgta gaacaaggtc
    86581 tcatcccttt agatggtagc cagactgttc ttctatcagg ctttggtgga ggcttgacct
    86641 ggggcacgct cattcttaca atttaggtaa tcatgtggtg aacacattgt tataaaaaaa
    86701 ctatttattt taaaggagtc ctatcatggc agtatttgaa aaagtacaag aaattatcgt
    86761 tgaagaactt ggaaaagacg catcagaagt aacacttgaa tcaacttttg atgatttgga
    86821 cgcagattca ttggacttgt tccaagtaat ctcagaaatc gaagatgctt ttgatatcca
    86881 aatcgaagca gaaaatgact tgaaaacagt tggtgacttg gttgcttacg ttgaagagca
    86941 agcaaaataa gcagaatatt agtagaagga gtagggagaa acccactccc tcttgtttag
    87001 gtaatagttt gactgtcaaa ttatggtgaa atcgaactat tacgtaagca aggaaggttg
    87061 gaggcactat gaaaacgcgt attacagaat tattgaagat tgactatcct attttccaag
    87121 gagggatggc ctgggttgct gatggtgatt tggcaggggc tgtttccaag gctggaggat
    87181 taggaattat cggtggggga aatgccccga aagaagttgt caaggccaat attgataaaa
    87241 tcaaatcatt gactgataaa ccctttgggg tcaacatcat gctcttatct ccctttgtgg
    87301 aagatatcgt ggatctcgtt attgaagaag gtgttaaagt tgtcacaaca ggagcaggaa
    87361 atccaagcaa gtatatggaa cgtttccatg aagctgggat aatcgttatt cctgttgttc
    87421 ctagtgtcgc tttagctaaa cgcatggaaa aaatcggtgc agacgctgtt attgcagaag
    87481 gaatggaagc tggggggcat atcggtaaat taacaaccat gaccttggtg cgacaggtag
    87541 ccacagctat atctattcct gttattgctg caggaggaat tgcggatggt gaaggtgctg
    87601 cggctggctt tatgctaggt gcagaggctg tacaggtggg gacacggttt gtagttgcaa
    87661 aagagtcgaa tgcccatcca aactacaagg agaaaatttt aaaagcaagg gatattgaca
    87721 ctacgatttc agctcagcac tttggtcatg ctgttcgtgc tattaaaaat cagttgacta
    87781 gagattttga actggctgaa aaagatgcct ttaagcagga agatcctgat ttagaaatct
    87841 ttgaacaaat gggagcaggt gccctagcca aagcagttgt tcacggtgat gtggatggtg
    87901 gctctgtcat ggcaggtcaa atcgcagggc ttgtttctaa agaagaaaca gctgaagaaa
    87961 tcctaaaaga tttgtattac ggagccgcta agaaaattca agaagaagcc tctcgctgga
    88021 caggagttgt aagaaatgac taaaacagcc tttttatttg ctggtcaagg tgcccagtat
    88081 ctagggatgg gacgggattt ctatgatcag tatccgattg ttaaagaaac gattgatcga
    88141 gcgagtcagg tgctcggtta tgatttgcgt tatctcatcg atacggaaga ggacaaactc
    88201 aatcagaccc gctatacgca accagccatt ctagcgactt cggttgctat ctaccgttta
    88261 ttgcaagaaa agggctatca gcctgatatg gttgctggtt tgtctcttgg agaatactct
    88321 gccttggtgg caagcggcgc cttggatttt gaagatgcgg ttgccttggt agctaagcgt
    88381 ggagcctata tggaagaagc gactcctgct gactctggca agatggtagc agttctcaat
    88441 acgccagtag aggtcattga agaagcctgt caaaaagctt ctgaacttgg agtggttact
    88501 ccagccaact ataacacacc tgcacaaatc gtcattgctg gagaagtggt tgcagttgat
    88561 cgagcggttg aacttttgca agaagcaggt gccaaacgct tgattcctct taaggtgtca
    88621 ggtccctttc acaccgctct ccttgagcca gctagccaga aactagctga aactctagct
    88681 caggtaagtt tttcagattt tacttgtccc ctagtcggca atacagaagc tgctgtgatg
    88741 caaaaagagg acattgctca gctcttgacg cgtcaggtca aggaacccgt tcgtttctat
    88801 gaaagtattg gggtcatgca agaagcaggc ataagcaact ttatcgagat tggaccgggg
    88861 aaagtcttgt caggttttgt taaaaaaatt gatcaaactg ctcacttagc tcatgtggaa
    88921 gatcaagcga gtttagtagc acttttagaa aaatagacta aaataagtag aagttttgaa
    88981 aggaaaaaaa tgaaactaga acataaaaat atctttatta caggttcgag tcgtggaatt
    89041 ggtcttgcca tcgcccacaa gtttgctcaa gcaggagcca acattgtctt aaacagtcgt
    89101 ggggcaatct cagaagaatt gctctctgag ttttcaaact atggtatcaa ggtggttccc
    89161 atttcaggag atgtatcaga ttttgcagac gctaagcgta tgattgatca agctattgca
    89221 gaactgggtt cagtagatgt tttggtcaac aatgcaggga ttacccaaga tactcttatg
    89281 ctcaagatga cagaagcaga ttttgaaaaa gtgctcaagg tcaatctgac tggtgccttt
    89341 aatatgacac aatcagtctt gaaaccgatg atgaaagcca gagaaggtgc tatcattaat
    89401 atgtctagtg ttgttggttt gatggggaat attggtcaag ctaactatgc tgcttctaag
    89461 gctggcttga ttggctttac caagtctgtg gcacgcgagg tcgctagtcg gaatatacga
    89521 gtcaatgtga ttgctccagg aatgattgag tctgatatga cagctatctt atcagataag
    89581 attaaggaag ctacactagc tcagattccg atgaaagaat ttgggcaggc agagcaggtt
    89641 gcagatttga cagtattttt agcaggccaa gattatctaa ctggtcaagt gattgccatt
    89701 gatggtggct taagtatgta gcgaaagcta gaggtgaaaa gaatgaaact aaatcgagta
    89761 gtggtaacag gttatggagt aacatctcca atcggaaata caccagaaga attttggaat
    89821 agtttagcaa ctgggaaaat cggcattggt ggcattacaa aatttgatca tagtgacttt
    89881 gatgtgcata atgcggcaga aatccaagat tttccgttcg ataaatactt tgtaaaaaaa
    89941 gataccaacc gttttgataa ctattcttta tatgccttgt atgcagccca agaggctgta
    90001 aatcatgcca atcttgatgt agaggctctt aatagggatc gttttggtgt tatcgttgca
    90061 tctggtattg gtggaatcaa ggaaattgaa gatcaggtac ttcgccttca tgaaaaagga
    90121 cccaaacgtg tcaaaccaat gactcttcca aaagctttac caaatatggc ttctgggaat
    90181 gtagccatgc gttttggtgc aaacggtgtt tgtaaatcta tcaatactgc ctgctcttca
    90241 tcaaatgatg cgattgggga tgccttccgc tccattaagt ttggtttcca agatgtgatg
    90301 ttggtgggag gaacagaagc ttctatcaca ccttttgcca tcgctggttt ccaagcctta
    90361 acagctctct ctactacaga ggatccaact cgtgcttcga tcccatttga taaggatcgc
    90421 aatgggtttg ttatgggtga aggttcaggg atgttggttc tagaaagtct tgaacacgct
    90481 gaaaaacgtg gagctactat cctggctgaa gtggttggtt acggaaatac ttgtgatgcc
    90541 taccacatga cttctccaca tccagaaggt cagggagcta tcaaggccat caaactagcc
    90601 ttggaagaag ctgagatttc tccagagcaa gtagcctatg tcaatgctca cggaacgtca
    90661 actcctgcca atgaaaaagg agaaagtggt gctatcgtag ctgttcttgg taaggaagta
    90721 cctgtatcat caaccaagtc ttttacagga catttgctgg gggctgcggg tgcagtagaa
    90781 gctatcgtca ccatcgaagc tatgcgtcat aactttgtac caatgacagc tgggacaagt
    90841 gaagtatcag attatatcga agctaatgtc gtttatggac aaggtttgga gaaagaaatt
    90901 ccatacgcta tttcaaatac ttttggtttt ggaggccaca atgcagttct tgctttcaaa
    90961 cgttgggaga atagataagt atgaatttaa acgatattaa agacttgatg actcaatttg
    91021 accagtcaag tttgagagaa ttttcttata aaaatgggac ggatgagttg cagtttagca
    91081 agaatgaagc aagacctgtg cctgaagttg caactcaagt cgctccagca cccgttctag
    91141 caacaccgag tccagtagct cctacatctg ctccagcaga gactgtagca gaagaagttc
    91201 cagctccagc tgaagcaagt gtggctactg agggaaatct tgtagagagt ccacttgttg
    91261 gagtggttta cttggctgct ggaccagata aacctgcctt cgttacagtt ggtgatagtg
    91321 tcaaaaaagg tcaaacattg gtaattatcg aagccatgaa agtcatgaat gaaatcccag
    91381 ctcctaagga tggtgtggta acggaaattc tcgtctctaa cgaagaaatg gttgagtttg
    91441 gtaaaggatt ggtacgtatc aaatgatcga tattcaagga atcaaagaag ctcttcccca
    91501 ccgttatcct atgcttctag tggaccgtgt cttggaagtg agcgaggata ccattgttgc
    91561 tatcaaaaat gtgaccatta acgaaccttt ctttaacggc cactttcctc aatacccagt
    91621 tatgccaggt gttctgatta tggaagcctt ggcgcaaact gctggtgtgt tggagttatc
    91681 aaaacctgaa aataaaggaa aactggtctt ttacgctggt atggacaagg ttaagttcaa
    91741 gaagcaagtt gtaccaggcg accaattggt tatgacagcg acttttgtaa aacgtcgtgg
    91801 caccatagct gtggttgaag caaaggctga agtggatggc aagcttgcag ccagtggtat
    91861 ccttactttt gcaattggga actaaggagg ttctccatgt ttcgaaaaat tttaattgcc
    91921 aatcgtggtg aaattgcggt tcgtattatc cgtgcggcac gtgaattggg gattgcgacg
    91981 gtagcggttt attcaactgc tgataaggaa gctcttcata cgcttttggc agatgaagca
    92041 gtttgtattg gtcctggcaa ggcaacagag tcttatctca atattaatgc agttctatca
    92101 gctgcagtct tgactgaggc agaagctatt caccctggtt ttggatttct cagtgaaaat
    92161 tccaaatttg cgaccatgtg tgaagaagta ggtatcaagt ttatcggtcc atctggtcat
    92221 gttatggata tgatggggga taagatcaat gcgcgtgctc agatgattaa agcaggtgtg
    92281 cctgttatac caggttcaga tggagaagtg cataactctg aagaagcttt gattgttgct
    92341 gaaaaaattg gctatcctgt tatgctcaag gcttcagcag gtggaggtgg taaagggatt
    92401 cgtaaggttg aaaaaccaga tgacctcgtt tctgcctttg aaactgcctc tagtgaggcc
    92461 aaggccaatt atggcaatgg tgccatgtac atagaacggg ttatctatcc agctcggcac
    92521 attgaggttc aaatcctagg tgatgagcat ggacatgtga ttcacttggg tgagcgggat
    92581 tgttctcttc aaaggaataa ccaaaaggtt ttggaagaaa gtccctcgat tgcaatcgga
    92641 aaaacgctgc gtcatgaaat aggtgctgct gctgttcgag cggcagagtt tgttggctat
    92701 gagaatgcag gaaccattga atttcttctt gatgaagcaa gtagcaattt ctatttcatg
    92761 gagatgaata ctcgtgttca ggtagaacat ccagtaacag agtttgtttc aggtgttgat
    92821 atcgttaagg aacagatttg cattgcggca ggtcagcctt tgtctgttaa gcaagaagat
    92881 attgtcctac gcggtcatgc catcgagtgt cgtatcaatg cagaaaaccc agcctttaac
    92941 tttgctccaa gtccaggtaa gattactaat ctctatctgc caagtggtgg agttggcttg
    93001 cgcgtggatt cagcagttta tccaggttat accattccgc cttattatga tagtatgatt
    93061 gccaaaatca tagtacacgg cgaaaatcgt tttgacgcct tgatgaaaat gcaacgtgcc
    93121 ctctatgaat tagagattga aggagtgcag accaatgcag atttccagct tgacctcatt
    93181 tcagatcgca atgtcattgc tggggattat gatacttcct tcttgatgga aaccttctta
    93241 cctaaatatc aagaaaaaga ataaaatgac tttaagagtt taaaccgaaa aggggaatca
    93301 atggctctat ttagtaaaaa agataagtat attcgaatca atcccaatcg ttcggttagg
    93361 gaaaaacctc aagctaagcc agaggttcca gatgaattat tttcccagtg tccaggctgt
    93421 aagcatacca tctatcagaa ggatctggga agtgaacgta tctgtccgca ctgtagctat
    93481 acctttcgta tttctgccca agaacgcttg gctttgacga ttgatatggg aaccttcaaa
    93541 gaattgttta cagggattga aagcaaggat cccttgcatt tccctggtta ccaaaagaaa
    93601 ctggcatcta tgcgtgaaaa aacaggtctg catgaagccg ttgtgacagg aactgctctt
    93661 attaaaggtc agactgtggc tcttgggatt atggattcta actttatcat ggcttctatg
    93721 ggtacggttg taggtgaaaa aatcactcgt ttgtttgagt atgcgactgt cgaaaaattg
    93781 ccagttgtcc tattcacagc ctctggtgga gcccgtatgc aggaaggaat catgagtctc
    93841 atgcagatgg ctaagatctc tgcggcggtt aaacgccatt caaatgctgg tctcttttac
    93901 ctgaccattt tgacagatcc aacgactggt ggtgtgacag cttctttcgc tatggaaggc
    93961 gatatcattc tggctgaacc acagagcttg gttggttttg ctggacgtcg tgtgattgaa
    94021 aatacggttc gtgaaagctt gcctgaggat ttccaaaagg cagaattcct attagaacat
    94081 ggctttgtgg atgctattgt caaaagaaga gacttaccag atacgattgc tagcctagtc
    94141 agattgcatg gagggagtcc tagatgaata ttgcaaaaat agtcagagaa gcgcgtgagc
    94201 agagtcgctt gacaaccttg gactttgcta caggcatttt tgatgaattt atccaattac
    94261 atggtgaccg ttcttttcgt gatgatggtg cagttgttgg tggtattggt tggcttggag
    94321 accaagctgt aacagtggtt ggtatccaaa aaggcaagag tttgcaagac aacctcaaac
    94381 ggaattttgg ccaaccacat ccagaaggct accgaaaggc actgcggttg atgaaacagg
    94441 ctgagaaatt tggccgtcca gttgtgacct ttatcaatac agcaggtgct tatcctggtg
    94501 tcggagcgga agaacgtggt caaggggaag ctatcgctcg caatctcatg gaaatgagtg
    94561 acctgaaagt tcctattatc gccattatta tcggtgaagg tggttcaggc ggggctctgg
    94621 ctctagctgt cgcggaccgt gtctggatgc tggaaaattc tatctatgcc attctcagtc
    94681 cagaaggctt tgcttccatt ttatggaagg acggtactcg cgccatggaa gcagcagaac
    94741 tgatgaaaat cacttcgcat gaactgttag aaatggacgt ggtggataag gtgatttctg
    94801 aagtaggact ttctagtaaa gaactgatta agagtgtcaa aaaagaactc caaacggagc
    94861 tggctagact ttcacaaaaa ccgctagaag agttgctgga agaacgctat caacgattta
    94921 gaaaatacta agaatgacta aatgagacta gaaaggtctc attttttatg gaaaaatgca
    94981 attcaggttg aaaaattgac agttgaggag atgggctata aaatagacaa aaaagatgta
    95041 tactgtagat gtaagcttac aaaaatttat agtgtattga atctataaca gtacaccttg
    95101 gctgctaaaa tatttctata aattaatttg actttcctga tagagttgtt cacatcttat
    95161 ttcaaatcac tatattttaa gaaggtactt gcaatgacag gtacagaaac atttacagtt
    95221 atttcaactg aggacttgga gcaaacttca agtggtcttg ctgtttggga agatggatat
    95281 agtagatggt tatattatag agaatttgct ccctatatga ggcaaggggc acttaattct
    95341 tatatagatg cttggaagta cggcttccga acagggtaat ctttcaaaaa agtacgatga
    95401 gaaacacaaa gaaactaaga caatttggaa tatttttgct tattatttta ctatctacct
    95461 atttaccaca aacaattgga ttgtatgtga cgatcatttt agggttagga gctgatgtct
    95521 attctcttat tttaacagtg ggattagtgg gaagtttcct tttctattaa tttggaggtt
    95581 aaaaaagaaa aagagctggg actggtcatt tgtcttctcc ttatttgcaa cttatgtggt
    95641 ttatcagatt ctcggtaatt tttgggcacg ctatgctcat ttgattaatc ataggaatat
    95701 tcatgatgag tattttaccg tggttctttc aaatggacaa ccaacctttt tatcgactat
    95761 cttatctttt gtcctgcctg taatcatcgg tcctgttttt gaggagactc ttgatagagg
    95821 gtattttatg aacaccttct ttccctagtc caagtattat ttggatgtta tcctatctgc
    95881 tatcatcttt gggattagcc atttgatact atctcacaga gatccaatta gtttattata
    95941 ttatagtctg attggtttct tttttgccct tgtttatcgt tctaccgaca atctgagatt
    96001 aacgattctc tgccatagtt tttttaactt tctcaatcat gcaaaaccta tctggatttt
    96061 tgtttacaat tatatctatt atcatttttt tagatagtgg gaggcaaaga aaaaagtgtt
    96121 tgatatctat caaacacttt ttctttttat tgttcttctg ttacaaactg gctgagcagt
    96181 ccattgataa aacgggcaga tttttgatcg gagaagtcct ttgcaagctc gatagcttca
    96241 ttaacagcaa ccagctgagg agtgtcaaat gaagtgattt caaagactcc caagcgaagg
    96301 aggtttctct ccacgagcgt taagcgttca atggtccaac ctgcttttaa atgctgagtg
    96361 atttgcttat ctagttcttc ctttttagct tgaacaccag aaacgaggtc tatcaaaaag
    96421 gctggaagtt gtacatccgt atcttcacga tcatgagtat aggcgaaacg acaagcagtt
    96481 tcgacatccg taccgaactc aaggctcatg agagcttgaa aagcgcattt acggagttgg
    96541 cgtctagatt ctaatagtgg actagtcatt gaggaagtcc tcgtcaaata gatctttcaa
    96601 ttctggtttt ggtgttttat ctgggacgat acctgcaacg tgaatattga tagcagcgag
    96661 ttctacatca gccatattac ggacggcatc tttgacagct ttctggatag caaccgctac
    96721 cttaggaact tttactccgt actcaaggta gagatagata tctgctgtga gttcttcgtc
    96781 cacgttttta agataaatgc cacggccgag tgaaagtttt gaaagggtat cagacactga
    96841 tctgtttgaa aaagagtgaa caccctctac ctttgcagta gcgatagcaa tgattttttc
    96901 aagtacacgt ggggcgataa cgatttcgcc aagttgttct tcaattccca tagaatgacc
    96961 tctttctaga gattaggcac gagaaacgta agttccttct gcagtgttga taacgagttt
    97021 ttgtcctgct tcgatgaagt ctggaacgtt tacgacaagt ccagtttcca tcgttgctgg
    97081 tttaccagaa cctgtaacag tagcaccttt gatagatggt tgagtttcag caactgtcaa
    97141 ctcaacagta gtaggaacgg tgacaccgat cacttcagtt ccgtagaatt ggattttcac
    97201 atcagagttt tcaaggatgt aaagcaattc gttttcaaca ttgactacag ggatttcgta
    97261 ttggtcataa gtttctgtat tcatgaagta tgctgtgtca tccattttgt acaagtattg
    97321 agctgggaca gtctcgataa tagcttgttc aaatttttcc tctggacggt agcttgtgtc
    97381 aaatgtagaa ccagtacgga catcacgcaa tttcatacgc atgatcgtgt ttcctttacc
    97441 tggtttgtgg tgactagctt ccaaaacgcg aatcaatttg ccgtcagctg tttcaaaggt
    97501 cataccagct tttaatttac ttgcttcaat catgttttta cctctttaat aaatattatt
    97561 actcttcatt ttaccataaa atactctgga aataaagcca aaatagttat tgggagttgg
    97621 taggagcgaa aaagaatatt ggctagtcag gtggagtggt taatgttaaa gagtatccac
    97681 tatatttctt ctcatactca atggaaatca aagagcaaac taggaagcta gccgcaggct
    97741 gctcaaaaca ctgttttgag gttgtggata gaactgacga agtcagtaac catatatacg
    97801 gtaatgtgac gctgacgtgg tctgaagaga ttttcgaaga gtattatatt tcaaaaggcc
    97861 gaagtaagtt tactccgacc tgttagtatt gtcttaaaaa gattgatttt ttattctggt
    97921 tctaccaaaa ttttaatttg tgacttatct tgagttaatt cgataaagtc ttcttcgacg
    97981 atattttcca atttaatttt cttagtaact aatttttcag cagagaagta gccttgttcc
    98041 atcaattcta atactttagg gaagatatga cgataagcaa tgattccttt tagtgtcttt
    98101 tcttggattg caaattcatt cggattaata tttgcttctc gttcccagat agagaccacc
    98161 atgcactcac ctgctttatg tacggcagct aaggcttgtc ctaaaactac tggcacaccc
    98221 gttacttcat aagaaacatc tacaccaccg tttgttaaac gatgaatagc ttcaacagct
    98281 gtttcacctt cttccggacg gacaacgata gctcctaact cttcagcttt tgcttgacgt
    98341 tcaggtgata gttcaacagc ataaatctta gaagcaccag ctgcacgaag agcttctaca
    98401 attaatagac caatcgggcc taaaccaaag acaacagctg tatcgccagc cttcaaagaa
    98461 gattgacgaa cagcatagac tgcaacagca gcgggttcag taagagcagc ttgctcatag
    98521 ctcaaactat ctggaatgac atgtactaag tcaccgtcta aaacacaata tttggcaaat
    98581 ccaccgtctg cagccaaacc gacaaaatta aggtttggat ccaaattata atcaccaact
    98641 aagttatttt tagctagaat tggttccaca gcaacacgat caccaacttt aacacgggta
    98701 acatcgcttc cgacttctat gatttcacca gaaaattcat gtcccagtgt taccggtgct
    98761 ttttgaccag aatagacgtg ctcatctgtt gggataaaga taggtccatc taaaaattca
    98821 tggaggtcag taccacaaat tcctgtgaac ttaactgcaa cttttacttg gtgcggaagt
    98881 acttcaggaa cttctatttc ttgaatacga acatctttcg ctgcatgcca gcgagctgcc
    98941 ttcattgtag ccatataaat aactccttat tgttgcgatt tttagttttc ttgtttggaa
    99001 actttacacg caatattgca aacgttttct ttctatttgt caagaaaaaa ccaaccttag
    99061 ggctggtttt gttctgtcta gttttctttc aacttcgcca attcctgtgc aagtagttta
    99121 agggcaactt gtgggttggc ttggcctttg gttgccttca taaggaatcc tgtgaaggcc
    99181 ttgtctgcat tacgtttgcc tgacttgaag tcggcaacag cagcttcgtt atccgcaaag
    99241 acttggtgga taattggaat caaaacagct ggatctgaaa tttgaaccat acctgctttt
    99301 tccacgtatt cacgcgcgcc accgccattt ttagctagat ggacaaagac tttcttggca
    99361 atcttagatg aaatagtacc gtcttcgatg atggcaatca tttcaaccaa gttttctggt
    99421 gtcaattcga tttgttccag tgttttacct tcagcattca agaactgagc gacttcccct
    99481 tggagccagt tagagacttg tttggcatca ccacctaggg caacagcttt ttcaaagaag
    99541 tcagaagtga ctttattagc agtcaactga ctagcatcgt agtctgataa accaaggtca
    99601 gatacataac gcgcacgacg ttcttttgga aactctggca actcagtccg catttcctca
    99661 atccactcgt cagaaatttc aaagaggggt aggtctggtt ctgggaagta gcggtagtca
    99721 gcagcccctt ccttgacacg catgaggatg gttgctttat tcgcttcatc gtaacggcgt
    99781 gtttcttggc ggatttgacc acctgagcga agaatttcag cctggcgttg gacttcgtat
    99841 tcaagacctt tacgaacgtt tgagaaggag ttgaggttct tcaattcagt cttggtaccg
    99901 aatttctctt gaccataagg acgaagggag atgttggcat ccacacgcat cgaaccttcc
    99961 tccatcttaa cgtcagaaat gccagcgtac tggataactt ccttgagggc tgtcagataa
   100021 gcataggctt cttcaggaga acgcatatct gcctcagata caatctcaat caagggaacc
   100081 ccttggcggt tgaggtcaac ataagagtag ccatctgtac catgggtgtt tttaccagcg
   100141 tcttcctcta ggtgggcacg ttcgataccg attttcttgg tcgtaccgtc ttctagttcg
   100201 acttcaatcc agccgttata accgattggc tcatcaaact gagaaatttg gtaggctttg
   100261 ggattatcag ggtagaagta gttcttgcgg tcaaagtgca tctttttgtg gatgtccatg
   100321 ttgagggcaa gagcagcctt gattccggca tcgacaaccc ctttattgag aactggcaga
   100381 actcctggga aagaccagtc aatcacgtta gtgttggcat tttgatcatt tccgaagtgg
   100441 gcagaagtag gtgagaagat ttttgaattg gtgttgagct ctacgtggac ttcaagtccg
   100501 atgactgttt caaagttcat tagttgtcac ctccaaaaat cacgggttgt tgtttgtggt
   100561 agcctgttgt tgcttcaaag gcagcagcaa cttggtaaat ggtttcctca gagtgcttgg
   100621 gaccaatcaa ttgcagaccg acaggtagac cttgagagaa tccagcagga atcgaaattc
   100681 caggcagtcc tgccaagttt acaggtatgg tcaataggtc ggctaagtac atggcaactg
   100741 ggtcatggtt gagagaatcc aagtcatagg caacacttgg agcagttgga cccaaaatca
   100801 aatcgtaatc cgcgaagact ttttcgaaat cttgaatgat aagtgtacgg acctgtccag
   100861 ccttcttata gtaggcatcg tagtaacctg atgaaagact gaaagtaccc agcatgatac
   100921 ggcgcttcac ttcttcacca aaaccttggc ttcggctgtt tacatagatt tcatcaaggt
   100981 tggttgcatc ttctgcgcga tagccgtaac ggataccgtc aaagcgttgc aagtttgatg
   101041 aagcttctga tgaagcgatg atgtagtata cggcaactcc gtatttagag tgaggaaggc
   101101 tgacttcttc gacaatagca cccaattttt caaagtgttt agcggcattt agaatggttt
   101161 ccttaacctc tgggttaatt ccttcaccga ggtattcctt aggcaaagcg attttcatac
   101221 ccttgatgtc ttggccgatt tttgaagtaa agtcggcgat gcggacagga gcagaagtag
   101281 agtctttagc atcttcgctg gcaatagcgt tgagcaagag ggcattttcc ttaacagtag
   101341 gagcaaaagg tccaatctgg tctaatgagc taccaaaggc aatgagaccg aaacgtgaaa
   101401 ctgttccgta ggttggtttg agaccaacga ttccgttgaa ggcagcaggt tggcggatgg
   101461 aaccaccagt atcagaacca agtgacaagc gaacttgtcc tgaggctaca gctgcggcag
   101521 aaccacttga tgacccacca ggaaccttgc tgtggtccca agcgttttta gttgctccgt
   101581 agtgtgaagt ttcacctgaa ccacccatag caaattcgtc catgttggtc tttccaacga
   101641 caatcatgcc cttggttttt gcattggcaa cagctgtcgc atcaaagatt ggctcatagt
   101701 tgtagagcat ttttgaggca gcagttgtga gaataccgtc tgtagagatg ttatccttaa
   101761 cagcaagtgg aattcctgaa aggacattgt cagcatcaat tccagcttca tcaatggctt
   101821 tagcttgaac aagagcttgc tcctcagcga tggtgacaaa tgaattgagg gcttcctcac
   101881 gagacttgat attttcaagt gttgcttggg tcaattctgt tgcagaaatt tccttagaga
   101941 caaggagatt gtgcaactct tcaatagttt tattgttaaa agtcattagg catctcctcc
   102001 attgtctagg atagctggca ccttgatata gtagttgtct ttttcaggta cgtttttaaa
   102061 caagcgatca cggtctattc cttcttcggc cacatcaggg cggagtacag tcttgcggtc
   102121 agccatagtc gtagtaggtg cgacaccagt tgtgtcaact tcgcccagca attcaaccat
   102181 gtcaacaatc ttagacaagg tggtcgcaaa ggcagcagtt tcttcttcag agaatcttaa
   102241 ttttgaaaga ttggcaacgt gtgttacctc ttcttgcgta attttcatct tgcatccttt
   102301 cgtgaaatga tgatttttag tctgttctat tttaccatat tttcctataa ataagggagg
   102361 gggaagtgaa aagaaataga aattgaaaaa aatgctaaaa tccgatataa tggagtgttg
   102421 aaaggaatgg taaaatccaa tgtaaaaatc attctcagct attgaaacaa gaaaaataga
   102481 gaatcaaaga aagagaactt atgaatattc aagaagaaat taagaaacgt cgtacctttg
   102541 ccattatctc ccacccggac gcggggaaaa caaccatcac tgagcagtta ctctactttg
   102601 ggggtgagat tcgtgaggct ggtacggtaa aagggaagaa aacagggact tttgctaaat
   102661 ctgactggat ggatatcgag aagcaacgtg ggatttctgt tacttcatct gttatgcaat
   102721 ttgactacga cggcaagcgc gtgaatatct tagacacgcc agggcacgag gacttctcag
   102781 aagataccta tcgtaccttg atggcggtgg atgctgcggt catggtcgtg gactctgcca
   102841 aggggatcga ggctcaaacc aagaaattgt ttgaggttgt gaaacatcgt ggcattccag
   102901 tttttacctt tatgaacaag ctggaccgtg acggtcgtga gcctttggat ctcttgcaag
   102961 aattggaaga aatcttgggc attgctagct accctatgaa ctggcctatc gggatgggga
   103021 aagcctttga gggcttgtat gacctctata accaacgttt agagctttac aaaggggatg
   103081 agcgttttgc cagtctagaa gacggggaca aactctttgg tagcaatcct ttctacgagc
   103141 aagtcaagga tgacattgag cttttaaatg aagctgggaa tgagttttca gaggaagcta
   103201 ttctggctgg agaattgacg cctgtctttt tcggttcagc cctgacaaac tttggtgtgc
   103261 agaccttcct tgaaatcttc ctcaagtttg ctccagaacc acatggtcac aagaaaacag
   103321 acggtgaaat tgtgaatcct tatgacaagg atttctcagg ctttgtcttt aaaatccaag
   103381 ccaacatgga tcctcgtcac cgtgaccgta ttgcctttgt ccgtatcgta tcaggcgaat
   103441 ttgagcgcgg catgagtgtc aatctccctc gtactggtaa gggggctaaa ctatctaatg
   103501 ttacccagtt tatggcggaa agtcgtgaga atgtgatcaa tgccgtggca ggtgatatta
   103561 tcggggttta cgataccggt acttatcagg ttggggatac cttgacggtt ggaaaaaaca
   103621 agtttgaatt tgaaccactg ccaaccttta ctcctgaaat tttcatgaaa gtttctgcta
   103681 agaatgttat gaagcaaaaa tccttccaca aggggattga gcaattggtg caagaaggag
   103741 ccgttcagct ttataagaat taccaaacag gtgagtacat gctgggagct gttggtcaac
   103801 tccagtttga agtctttaaa caccgtatgg aaggcgaata caatgcggaa gtggtcatga
   103861 gcccaatggg taaaaagacc gttcgttgga tcaagcctga ggacttggat gaacggatgt
   103921 cgtcaagtcg caatatctta gccaaagacc gttttgacca accagtcttt ctctttgaaa
   103981 atgactttgc cctccgctgg tttgcggaca agtatccaga cgtagagtta gaggagaaga
   104041 tgtgactcag taccaacaat tggaactaaa gttccaattg ttggacgcta gtcgctattt
   104101 ggcgaactag ctaactgcct cactaactac gtttggcaaa tagaatcgat ttgccaaact
   104161 ccgtgtcgta atctaataat cggtaaccgc tatggcggct tacctaaacg cttcactagg
   104221 aaaaatccac gaatggtatt gatttgtgga tttttccgtc gtagcagaaa gtaggtagcc
   104281 tagctaactg ccttactaac tacgtttggc aaatgaaatc gatttgtaaa actccgtgtc
   104341 gtaatgtaaa aattgtaaac cgtaatggga cttcatctaa aatctccact ggtatggttt
   104401 tacgaacgaa taggcgaaaa taatggttac gtagaaacat atgatgggaa taaaaagaaa
   104461 tgagataaaa agtgaaagaa gagaaaaaag cgattgtctt aggtgcagat aatgcttata
   104521 tggataaagt tgaaacaaca ataaaatctc tttgtgttca tctattataa tcttaagttt
   104581 tatgttttta atgatgacct tccgcgagaa tggttccaat tgatggaaaa aagactagag
   104641 actttgaata gtgagattgt gaatgtttag attgacagta gtattctgaa aggttatcgt
   104701 ctcccctttg agggactttc atatgcggct tttttagata ttttattcca aagtatgtaa
   104761 gcgagtctcg tgtactgtat ttggatttag atattgttgt aagaaaatcg atagatgagc
   104821 tgtgggattt ggacttgacg gctataccct tagctgcagt tagagatgat ttttatacac
   104881 ataattttaa ttctggtgtt ctgttaatca acaatggcat gtggagagca gaaaatgtca
   104941 cgcaagacct gatttaagac acaaataaaa aatcttccaa ttcccttgca aaaaacaaga
   105001 aagtgtgata acatagtacg gtatgtggtg ctagcacatc cgctatatta gatctaatag
   105061 gaggaaaaca caatggctaa agtatgttac tttacaggtc gtaagactgt atcaggaaac
   105121 aaccgttcac acgcgatgaa ccaaacaaaa cgtgccgtaa aaccaaacct tcaaaaagtt
   105181 actgttctta tcgatggtaa acctaaaaaa gtttgggctt cagctcgtgc tttgaaatca
   105241 ggtaaagttg aacgcgttta ataataaaag caaaggagac cttagggtct tttttctttt
   105301 attgtgggta taacatcgtt tgaaaaatag agtaaatatc cgctgataca tcattctgct
   105361 tttacacttg ggctgaaata tgataaaata gagtatcaac tagttgaggt aaaaaggatg
   105421 actgtaaaaa ttaatacaaa agatggtcaa atcgaactaa cagatgaagt gattgcaacc
   105481 gtcgtaggtg gagcagcaac tgagattttt ggtgtggtcg gtatggctag taaaaatgcc
   105541 ctcaaagata atttccaagc cctgctaggt aaggaaaatt attctaaagg tgtcgtcgta
   105601 aaggcagccg aagatggcag tattgcagtt gatgtatata ccgtgttaag ctacggaaca
   105661 aagattagtg aagtgtcaaa aaacattcaa gagcgtgttg cctttagctt ggaaaaccag
   105721 cttggaatta ctgctcagac tgtaaatgtc tacattcaaa atatcaaagt tgtaggagaa
   105781 taatcgtgtc aaaaattact actagcttat ttcaagaaat ggtgcaggct gcatcaactc
   105841 gcttgaataa gcaagctgaa tatgtcaatt cattaaacgt ctttccagtt ccagatggag
   105901 atactgggac aaatatggga atgaccattg aaaatggtgc taaagaagtt gcagacaagc
   105961 cagcttctac agttggagaa gtagcgagca ttcttgccaa agggcttttg atgggtgcgc
   106021 gtgggaactc aggagtgatt acgtctcagc ttttccgtgg attttcccaa gctatcaagg
   106081 ataaagacga gttaacaggt caagacttgg ctctggcctt ccaatcaggt gtggaagttg
   106141 cctataaggc agtgatgaaa cctgttgaag gaacgatttt aacagtttct cgtggagctg
   106201 ctatcggtgc taagaaaaaa gctgagcaaa cagatgacgc tgttgaagtc atgcgcgcag
   106261 ccttggaagg tgctaaaaca gctctagcta aaacaccaga catgcttcca gtattgaaag
   106321 aagttggcgt tgtggactca ggtggtcaag gattggtctt catctacgaa ggtttccttt
   106381 cagcccttac tggcgaatat attgcatctg aggactttgt agcgactcct gccaacatga
   106441 gtgagatgat caatgtagag catcataagt ctgtagctgg tcacgtagcg actgaggaca
   106501 tcacgtttgg ttactgtact gaaatcatgg tagctcttaa gcaaggtcca acctatgcta
   106561 aagattttga ctacgatgaa ttccgtaact acttggatga gcttggagat tctctcctcg
   106621 ttgttaacga tgatgaaatt gtcaaagtcc atgttcatac agaagatcca ggacttgtta
   106681 tgcaagaagg tctcaaatat ggtagcttgg tcaaggtaaa agttgacaat atgcgtaacc
   106741 aacacgaagc acaggttgag aaagaagcta ctcaagttat caagtcggct gaagaaaaag
   106801 agtatgcttt gattgctgtg gtggctggta aaggtctagc agatatcttc tgttctcaag
   106861 gcgtggatta tgttatcgaa ggcggtcaaa ccatgaaccc ttcaacagaa gactttatca
   106921 aggctgttga acaggttaat gcccgtaaca tcatcttctt gccaaacaac aagaacatct
   106981 tcatggcagc tcaatctgcg gcagaagttt tggagcaacc agcggtagtg gtagaggctc
   107041 gcactcttcc tcaaggtatg acaagtcttc ttgcctttga tccaagcaag tccattgaag
   107101 aaaaccaaga gcgtatgaca gctgctctta gcgatgtcgt tagcggaagc gtcacaacag
   107161 ccgtgcgtga tacaacgatc gatggcttag aaatccatga aaacgataat ttaggtatgg
   107221 tggatggaaa aattcttgtg tcaaaccctg atatgcacca aacattgact gaaaccttga
   107281 aacatatgtt ggatgaagac agtgaaatcg taaccttcta tgtaggtgaa gacggaagcg
   107341 aagaacttgc caatgaaatc gctcaagaaa tcgtagaaga attcgaagac gttgaagtcg
   107401 agattcacca aggtcaacaa cctgtttacc catacctatt tagtgtggaa taagattaat
   107461 gaaggactga gaaatcagtt cttttttctt tttagtaaat gaaatcggta tctttttaat
   107521 aaaaacaaaa ataacattca taaataaacg ttaaaataga aaattcagaa aatttcttct
   107581 tttatcttga aaaattttga aaaaatggta tgatagtaac aagttatttt taagaggaaa
   107641 gaaaggggaa taatggagaa aatcagttta gaatctccta agacggggtc ggacctagtt
   107701 ttggaaacac ttcgtgattt aggagttgat accatctttg gttatcctgg tggtgcggtt
   107761 ttgccttttt atgatgcgat atataatttt aaaggcattc gccacattct agggcgccat
   107821 gagcaaggtt gtttgcatga agctgaaggt tatgccaaat caactggaaa gttgggtgtt
   107881 gccgtcgtca ctagtggacc aggagcaaca aatgccatta cagggattgc ggatgccatg
   107941 agcgatagcg ttcccctttt ggtctttaca ggtcaggtgg cgcgagcagg gattgggaag
   108001 gatgcctttc aggaggcaga catcgtggga attaccatgc caatcactaa gtacaattac
   108061 caagttcgtg agacagctga tattccgcgt atcattacgg aagctgtcca tatcgcaact
   108121 acaggccgtc cagggccagt tgtaattgac ctaccaaaag acatatctgc tttagaaaca
   108181 gacttcattt attcaccaga agtgaattta ccaagttatc agccgactct tgagccgaat
   108241 gatatgcaaa tcaagaaaat cttgaagcaa ttgtccaagg ctaaaaagcc agtcttgtta
   108301 gctggtggtg gaattagtta tgctgaggct gctacggaac taaatgaatt tgcagaacgc
   108361 tatcaaattc cagtggtaac cagtcttttg ggacaaggaa cgattgcaac gagtcaccca
   108421 ctctttcttg gaatgggagg catgcacggg tcattcgcag caaatattgc tatgacggaa
   108481 gcggacttta tgattagtat tggttctcgt ttcgatgacc gtttgacggg gaatcctaag
   108541 actttcgcta agaatgctaa ggttgcccac attgatattg acccagctga gattggcaag
   108601 attatcagtg cagacattcc tgtagttgga gatgctaaga aggccttgca aatgttgcta
   108661 gcagaaccaa cagttcacaa caacactgaa aagtggattg agaaagtcac taaagacaag
   108721 aatcgtgttc gttcttatga taagaaagag cgtgtggttc aaccgcaagc agttattgaa
   108781 cgaattggtg aattgacgaa tggagatgcc attgtggtaa cagacgttgg tcaacaccaa
   108841 atgtggacag ctcagtatta tccctaccaa aatgaacgtc agttagtgac ttcaggtggt
   108901 ttgggaacaa tgggctttgg aattccagca gcaatcggtg ctaaaattgc taacccagat
   108961 aaggaagtag tcttgtttgt tggggatggt ggtttccaaa tgaccaacca ggagttggct
   109021 attttgaata tttacaaggt gccaatcaag gtggttatgc tgaacaatca ttcacttgga
   109081 atggttcgcc agtggcagga atccttctat gaaggcagaa catcagagtc ggtctttgat
   109141 acccttcctg atttccaatt gatggcgcag gcttatggta ttaaaaacta taagtttgac
   109201 aatcctgaga ccttggctca agaccttgaa gtcatcactg aggatgttcc tatgctaatt
   109261 gaggtagata tttctcgtaa ggaacaggtg ttaccaatgg taccggctgg taagagtaat
   109321 catgagatgt tgggggtgca gttccatgcg tagaatgtta acagcaaaac tacaaaatcg
   109381 ttcaggagtc ctcaatcgct ttacaggtgt cctatctcgt cgtcaggtta atattgaaag
   109441 catctctgtt ggagcaacag aagatccgaa tgtatcgcgt atcactatta ttattgatgt
   109501 tgcttctcat gatgaagtgg agcaaatcat caaacagctc aatcgtcaga ttgatgtgat
   109561 tcgcattcga gatattacag acaagcctca tttggagcgc gaggtgattt tggttaagat
   109621 gtcagcgcca gctgagaaga gagctgagat tttagcgatt attcaacctt tccgtgcaac
   109681 agtagtagac gtagcgccaa gctcgattac cattcagatg acgggaaatg cagaaaagag
   109741 cgaagcccta ttgcgagtca ttcgcccata cggtattcgc aatattgctc gaacgggtgc
   109801 aactggattt acccgcgatt aaaaatccaa cttaaattta ttaaaccagc ctaaaaggca
   109861 ataaataata gaaaagagag aaaagctatg acagttcaaa tggaatatga aaaagatgtt
   109921 aaagtagcag cacttgacgg taaaaaaatc gccgttatcg gttatggttc acaagggcat
   109981 gcgcatgctc aaaacttgcg tgattcaggt cgtgacgtta ttatcggtgt acgtccaggt
   110041 aaatcttttg ataaagcaaa agaagatgga tttgatactt acacagtagc agaagctact
   110101 aagttggctg atgttattat gatcttggcg ccagacgaaa ttcaacaaga attgtacgaa
   110161 gcagaaatcg ctccaaactt ggaagctgga aacgcagttg gatttgccca tggtttcaac
   110221 atccactttg aatttatcaa agttcctgcg gatgtagatg tcttcatgtg tgctcctaaa
   110281 ggaccaggac acttggtacg tcgtacttac gaagaaggat ttggtgttcc agctctttat
   110341 gcagtatacc aagatgcaac aggaaatgct aaaaacattg ctatggactg gtgtaaaggt
   110401 gttggagcgg ctcgtgtagg tcttcttgaa acaacttaca aagaagaaac tgaagaagat
   110461 ttgtttggtg aacaagctgt actttgtggt ggtttgactg cccttatcga agcaggtttc
   110521 gaagtcttga cagaagcagg ttacgctcca gaattggctt actttgaagt tcttcacgaa
   110581 atgaaattga tcgttgactt gatctacgaa ggtggattca agaaaatgcg tcaatctatt
   110641 tcaaacactg ctgaatacgg tgactatgta tcaggtccac gtgtaatcac tgaacaagtt
   110701 aaagaaaata tgaaggctgt cttggcagac atccaaaatg gtaaatttgc aaatgacttt
   110761 gtaaatgact ataaagctgg acgtccaaaa ttgactgctt accgtgaaca agcagctaac
   110821 cttgaaattg aaaaagttgg tgcagaattg cgtaaagcaa tgccattcgt tggtaaaaac
   110881 gacgatgatg cattcaaaat ctataactaa ttagaaatat atagcgctgg agatgatttt
   110941 atgaaaaaga ttatgagaaa aattgcatcg ttattattgg ttctagttgt ataatgtaat
   111001 tacaccgtcg gtaatagtgc tagcagacca aaataaagca gattggtcgt atgatgaaaa
   111061 tgctgtaatt aacatttatg atgatgctaa ttttgaagat ggtaggttgc atatgacctt
   111121 tgaacaattc ttcaaattgg cacaaatagc tagagaagaa ggtcttgaaa ttcattctcc
   111181 gtttgagaga gctggtgcga ctaaatctgc tcgttatata gcgaaatgga ttttgagaaa
   111241 taaaaaatat taacaaatat agttggtaaa tcattaggac ctaaatcagc tgttagattc
   111301 ggagaagctt tatcctatat tgaaggtcct cttcgcagaa taaatgagac gatagatggc
   111361 ggtttatatc aaatagagca aattattgca tctggattga aagaatcggg tttaaatgac
   111421 tggactgcga aaactttagc ttcagctatt cgtgggatat tagatgtact tatttagggg
   111481 ttgaaatcat atgaatatta ccaatttgtt ttctatcaag acaggatgtg atgaaactga
   111541 taggcaactg caaaaactat tttttcagtt ggatttacaa ttgggagaat tgacagatca
   111601 actaagaaaa ttagattcta attttgttcc tcgtagtcaa tttgtagaca cgttggattt
   111661 gaatgatgta gaatataaag aaattttaaa ctattttatc ttccatcgta atgatagtga
   111721 agaaagtttg gtagaatggt tatatgattg gatttccaca aatcgttatg aacttcctaa
   111781 agagttttcg attcgtatgg ctcataaata ccatgaaagt gttactgaaa ttttcggaga
   111841 tgaataacta aaaaacagtc attagtgact gttttttata gaaaaagagg ttttatatgt
   111901 taagttcaaa agatataatc aaggctcaca aggtcttgaa cggtgtggtt gtgaatactc
   111961 cactggatta cgatcattat ttatcggaga agtatggtgc taagatttat ttgaaaaaag
   112021 aaaatgccca gcgtgttcgc tcctttaaaa ttcgtggtgc ctattatgcc atttcccagc
   112081 tcagcaagga agaacgtgaa cgtggggtag tttgcgcttc tgcgggaaat catgcgcagg
   112141 gagtagccta tacttgtaat gaaatgaaaa ttcctgctac tatctttatg cccattacta
   112201 cgccacaaca aaagattggt caggttcgct tttttggtgg ggattttgta actattaaac
   112261 tagttggaga tacctttgat gcctcagcca aagcagctca agaatttaca gtctctgaaa
   112321 atcgtacctt tattgatcct tttgatgatg ctcatgttca agcaggtcaa ggaacagttg
   112381 cttatgagat tttagaagaa gctcgaaaag aatcgattga ttttgatgct gtcttggttc
   112441 ctgttggtgg tggcggtctc attgccgggg tttctaccta tatcaaggaa acaagtccag
   112501 agattgaggt tatcggagta gaggcgaatg gagcgcgttc catgaaagct gcctttgagg
   112561 ctggaggtcc agtcaaactc aaggaaattg ataaatttgc ggatgggatt gctgtgcaaa
   112621 aggtaggtca gttgacctat gaagcaactc gtcaacatat tcaaactttg gtaggtgtcg
   112681 atgagggatt gatttctgaa accttgattg acctttactc taagcaaggg atagtcgcag
   112741 aacctgctgg agcagctagt atcgcctctt tagaggtttt agctgaatat attaagggga
   112801 aaaccatttg ttgtatcatt tctggaggaa ataatgatat caaccgtatg ccagaaatgg
   112861 aagagcgtgc cttgatttat gatggtatca aacattactt tgtggtcaat ttcccacaac
   112921 gtccaggagc tttgcgtgag tttgtaaatg atatcctggg gccaaatgat gatatcacac
   112981 gttttgagta tatcaaacga gctagcaagg gaacaggccc agtattaatt gggatcgctt
   113041 tagcagataa gcatgattat gcaggtttga ttcgtagaat ggaaggtttt gatccagctt
   113101 atattaactt aaatggtaat gaaacgcttt ataatatgct tgtctgagga ctaataaaaa
   113161 aatatcatat tatttgtaca actgatgtat atgtgctata atgaagatga agaaagggga
   113221 cgattcctat ggttttagaa aacttatcgt gcaattctta cttctgttca ttatagcact
   113281 tatgatgttt ggctcagatt tccatccttc attttgattt cctatctatt gacaagcata
   113341 gtcacactgt ctttaatact cttcgaaaat ctcttcaaac cacgttagct ctatctgcaa
   113401 cctcaaaaca gtgttttgag caacttgcgg ctagcttcct agtttgctct ttgattttca
   113461 ttgagtataa ggtatgattt gatttctttt tgttgacaaa tataccatat taaaaagata
   113521 tataagtaat taactgagct tatctgtctt gtcatcttta ttaaggatgg tttagataat
   113581 cgggtgtctg cttctaggct agcacctcaa tatccaaagg agtgatgaat ttgaaggaca
   113641 taaggaatac ctatctctca gatgatttat tgaggaagaa agataggagt ttttgagcta
   113701 gtgaaggctt ggatttctaa aggttagaac tatcatcttc agttcttaaa tcgaagaaat
   113761 aagctatctt acggaaatag agaagcattt tttaagaact tgaataattt cgcaccttaa
   113821 gagggtaata atacagtatt tttattagca aatatttatg gtgtagaggc tagcgaaacc
   113881 tatatattat cggatttaaa aaggaagtaa gaaaattctg aactaattat tttcgttgaa
   113941 tatatgtttt ttttattgac aaaagtagta aaaacgtata caattaaata ttataaagaa
   114001 gaaaatggga gaaaaacatg gctaagtcaa actttgaaaa agtagaatca gttgttggct
   114061 gggttcgtga taagaaaatc acaggctacc gtatctctaa agaaacgaat gcgcgtgaaa
   114121 tgtctatcat tgctctggcg cagggtcgtg caaaagtaaa aaatatttca tttgaaacag
   114181 ccctaggcct aattgatttc tatgaaaaaa attatgaaaa atttgaagat taatctttgg
   114241 ataacggcgg attcttgacc ttcaagtagt agagatagag aatctgcctt ttcattttga
   114301 ggacagcaaa aagactgcac ggttgatgca gccttttctt tttatttgag atagcgttga
   114361 aggaactctt ttgttcggtc ttctttagga ttggtgaaga ggtcttctgg tttaccttct
   114421 tcagcgatca cgcccttatc cataaagata acacggtgag agacatcacg ggcaaattcc
   114481 atttcatggg ttacgacaat catggtcaag ccttcctgag ccaggtcctg catgattttg
   114541 aggacttctc caaccatttc tggatcgaga gctgatgttg gttcatcaaa gagaatggcg
   114601 tccggattca tggagagggc acgagcgatg gccacacgtt gtttttgacc acctgagagt
   114661 tgttttggtt tggcttgcca gtagcgttct cccatgccga ccttttccag gttttctttg
   114721 gcaatctttt cagcttctgt gcgttcgcgt tttaggacag ttgtctgagc gacgattgtg
   114781 ttttcaagaa cattgagatt ttcaaagagg ttaaaggatt ggaaaaccat ccccaacttt
   114841 tcacggtatt gcgtgaggtc atagcctttt tcgaggacgt tttgtccatg ataaaggatt
   114901 tgtccatcag ttggtgtttc aagtaggtta atggagcgta ggaaggtcga ttttccgctt
   114961 ccagagcttc cgatgataga gatgacctct cccttgtgga cagtgagtga aatgtctttt
   115021 agcacttcgt tttgtccata ggattttttg aggtgtttaa tttcaaggat tgcttgtgtc
   115081 attatttcaa atcctccgtt tgcatttggt tagcacctgt agtgtaggta tccatgtcca
   115141 ttctgcgctc gataaagcgt aggatacgtg ttacggtgaa ggtgaggaca aagtaaatca
   115201 cggcgatgat tgtaaatgtc tggaagtatt gataggtttg tgttgccacg gtatttcctg
   115261 agaaataaag ttcgacaaca gagataacgt tcaatacaga tgtatctttg atattgatga
   115321 caaattcatt accagttgca ggtaggatgt tacggactac ctgaggtagg acaatcttac
   115381 gcatggtctg gttatgggtc ataccaagag cagtcgcagc ttcaaattgt cccttgtcaa
   115441 ctgctaggat accaccacgg acgatttcag tcatgtaggc accggtattg attgaaacga
   115501 tgaagatagc agctagtgta cggtcaaggt tgatcccgaa agcttgggca gttccatagt
   115561 agataaccat cgattgaaca atcattggcg taccacggaa aatttcaatg tagacattga
   115621 gaacccagcc gactagtttt tgaaggccat aaatggcttt gttttcagag agaggagcag
   115681 tacggaagac accaatggca agtccaataa tgagacctat gatggttccg acgatagaga
   115741 ttaaaagagt gataccagca ccacgcaaga gttgttgcca gttttcagaa agaattttag
   115801 cgacttggct aaagaaacta ctgctagtct cttcagttgt tgtagcttcg gcaggttgtt
   115861 ccttgatcat acgatccatc aaggcaactt ggtcatcttt tgaaatggtt tcaatgctgg
   115921 cattgatttg gctaatacga ttgtcatttt tacgaagccc gatagcgata gctgtatctt
   115981 cttccccagt tttgaaacca ggttctactt gaatcatctt gaacttagag ttcgcagctt
   116041 cagcagtcag tgcttctgga cgttcagaaa cataagcatc aatgacacca gcctcaagag
   116101 cttggcgcat ttgagcgaag tctcccatgg ctgtttcttt tttagcacct gggatttgtg
   116161 caatcaagtc gtagaggtag accccttgtt gagaagtgat ttttgcaccg ttaaagtcat
   116221 ccaaagattt agcacttacg taggcagaat cttttttgac aagcaaaact ggttcgctag
   116281 tgtagtaact gctcgaaaag gcaatttctt gtttgcgttc tgcagttgga ctcatacctg
   116341 cgataatcat gtcaatctta ccagaagtaa gggcagggac tagaccttcc cacttggttt
   116401 taacaaccaa aggttcttta cctaagtcct tagcgatttt cttggcgatt tgaacatcgt
   116461 atccgttggc atactgattg gtcccatcga ttttgacagc tccgttgcta tcatcatcct
   116521 gggtccagtt aaagggagca tatgctgctt ccatcccgat gcgtaaatat tcatcggctt
   116581 gagcaacatt gacaagtcct agcatcagca agagacttgt gaaaatagat aagtatattt
   116641 ttctcatgat ttctcctatt ctgatctatt aaaaaataac tgtctcctat tttatcgaaa
   116701 aatgcgtaat ttttcaacat aagtaagcct ttacttacga aaaaatgcta taatgataag
   116761 aaagataaaa agggggctta gttgatgaaa aaaacttttt tcttactggt gttaggcttg
   116821 ttttgccttc ttccactctc tgtttttgcc attgatttca agataaactc ttatcaaggg
   116881 gatttgtata ttcatgcaga taatacggca gagtttagac agaagatagt ttaccagttt
   116941 gaggaggact ttaagggaca aatcgtggga cttggacgtg ctggtaagat gcctagcggg
   117001 tttgacattg accctcatcc aaaggttcag gccgcgaaaa acggtgcaga actagcagat
   117061 gtgactagcg aagtaacaga agaagcggat ggttatactg tgagagtcta taatccaggt
   117121 caggagggcg acatagttga agttgacctc gtctggaact taaaaaattt acttttcctt
   117181 tatgatgata tcgctgaatt aaattggcaa cctctgacag atagttcaga gtctattgaa
   117241 aagtttgaat ttcatgtaag gggagacaag ggggctgaaa aactcttttt ccatacaggg
   117301 aaacttttta gagagggaac gattgaaaag agtaaccttg attatactat ccgtttagac
   117361 aatcttccgg ctaagcgtgg agttgagttg catgcctact ggcctcggac cgattttgct
   117421 agcgctaggg atcagggatt gaaagggaat cgtttagaag agtttaataa gatagaagac
   117481 tcgattgtta gagaaaaaga tcagagtaaa caacttgtta cttgggtcct cccttcgatc
   117541 ctttctatct ccttgttatt gagtgtctgc ttctatttta tttatagaag aaagaccact
   117601 ccttcagtca aatatgccaa aaatcatcgt ctctatgaac caccaatgga attagagcct
   117661 atggttttat cagaggctgt ctactcgacc tccttggagg aagtgagtcc cttagtcaag
   117721 ggggctggca aattcacttt tgaccaactt attcaagcta ccttgctaga tgtgatggac
   117781 cgtgggaatg tttctattat ttcagaagga gatgcagttg gcttgagatt ggtgaaagaa
   117841 gatggtttgt caagatttga gagagactgt ctaaatctag ccttttcagg caaaaaagaa
   117901 gccactcttt ccaatttgtt tgcggattac aaggtatctg acagccttta tcgcggagct
   117961 aaagctgctg atgagaaacg gattcaagca agagggattc agctcaaatc ttctttcgaa
   118021 gcagtattaa aagagatgca agaaggagtg agaaagcgag ttgtcttctg gggactccca
   118081 gattactatc gtcctttaac tggtttggaa aaggctttgc aagtgggtat gggtgtcttg
   118141 actatcttgc ccctatttat cggatttggt ttgttcttgt acagtttaga cgttcatggc
   118201 tatctttacc tccctttgcc aatacttggt tttctagggt tagttttgtc tgttttctat
   118261 tattggaagc ttcgactaga taatcgtgat ggtgttctaa atgaagcggg agctgaggtc
   118321 tactatctct ggaccagttt tgaaaatatg ttacgtgaga ttgcacgact ggataaggct
   118381 gaattggaaa gtattgttgt ttggaatcgt ctcttggtct atgcaacctt atttggctat
   118441 gcggacaagg ttagtcattt gatgaaggtt catcagattc aagttgaaaa tccagatatc
   118501 aatctctatg tagcttatgg ctggcacagt atgttttatc attcaagcgc gcaaatgagc
   118561 cattatgcta gtgtcgcaaa tacagcaagt acctactctg tatcttctgg aagtggaagt
   118621 tctggtggtg gcttctctgg aggcggaggt ggcggcagta tcggagcctt ttaaagagag
   118681 ctaccataga ctgaaaaagt atgatataat ggaagataga agaaagacaa actataagaa
   118741 aagtcaatag ttttatctaa actatttctt atttcaattt gatgatttgg cgatgatttt
   118801 agagcacggc aaaaagccct tgaaaaagtc cattttttca aaggtaatcc tgtgttaatt
   118861 tcagaaatta catcactttt tgttcgtcaa atggcagctc ttttttagga tataaaacag
   118921 ggttcggata agtttttttg caaggtggat gatggctaca ttgtaatgtt ttccttattc
   118981 taacttagtc ttaagatagg ccttaaaagc aggtgaaaag cgagcgcatg ctttggcagc
   119041 ttgtatgagt gcccaccgca gatgagggga accccgtttg atcattcttc cagctaaatc
   119101 aatctgacct gactgataaa tagaagaatc cagtccagcg aaagcttgta attgagcagg
   119161 attatcaaag gcatgaatat ttcgaatctc ggctaaaatg accgccccta aacgaccccc
   119221 aatcccagta accgtcgtga tgaccgagtt gaactcagcc atcaagtcat tgacacatgt
   119281 ttccgccttg tcaatgagcc tcttgtaatg tttgatgatt tcgatgattt cgaattcacg
   119341 agcaggagat gttgttccga tagaacgagg tgcgactgag aggatatcct gaattttaga
   119401 agcggtcaat cgcttaattt ctatcagctt atcaaatcct gcctcaagcc ttttctgagg
   119461 attagggtag cgtgtcaaga gttggtaggt atattctgaa tgctttccaa cgattttatc
   119521 caactcagga aagatgatat caagacaacg agtgtattgt actttccaat cagactgttt
   119581 tttcttgaga cgatgaatat gtctagccag tatttttagt tctacttgcc gattatcgtg
   119641 ttgaaattgt tcacgattgg ggtcagaaag aagtttaaga gcgatgagac agtcttggtt
   119701 gagctgtcga aaagacagat ctaagagttc aaaaccagct ttattatttg aaaaagtgag
   119761 tggtttaaga acagttttcc tcgaacattc aaggctgtaa catcgtgttt atttttagcg
   119821 acatcaatgc ccacataaag catgggagta cctccagata tagtatttca agtctacttg
   119881 gttatccacg aactttttgc cttgttacct tagacgagat aaaacgtcta tgcgttatca
   119941 aactcattac caattgaaac aaaaagctgt ggttagaccc tttcggaaat cgtcaagcga
   120001 ttggaggaaa tgaactaatc cacagtggct tattccaagt ataccacttg ggctttggca
   120061 gtagctaact gcgttaaata taatataagg agaaatatat gtatcttatt gaaattttaa
   120121 aatctatctt cttcgggatt gttgaaggaa ttacggaatg gttgccgatt tccagtacag
   120181 gtcacttgat tttagcagag gagtttatcc aataccaaaa tcaaaatgaa gcctttatgt
   120241 ccatgtttaa tgtcgtgatt cagcttggtg ctattttagc agttatggtg atttatttta
   120301 acaagctcaa tccttttaaa ccgactaagg acaaacagga agttcgtaag acttggagac
   120361 tatggttgaa ggtcttgatt gccactttgc ctttacttgg tgtctttaaa tttgatgatt
   120421 ggtttgatac ccacttccat aacatggttt cagttgctct catgttgatt atctacgggg
   120481 ttgccttcat ctatttggaa aagcgcaata aagcgcgtgc tatcgagcca agtgtaacag
   120541 agttggacaa gcttccttat acgaccgctt tctatatcgg actcttccaa gttcttgctc
   120601 ttttaccagg gactagccgt tcaggtgcaa cgattgtcgg tggtttgtta aatggaacca
   120661 gtcgttcagt tgtgacagaa tttaccttct atcttgggat tcccgttatg tttggagcta
   120721 gtgccttaaa gattttcaaa tttgtgaaag ccggagaact cttgagcttt gggcaattgt
   120781 ttttgctctt ggtcgcgatg ggagtagctt ttgcggtcag catggtggct attcgcttct
   120841 tgaccagcta tgtgaaaaaa cacgacttca ccctttttgg taaataccgt atcgtgcttg
   120901 gtagtgtttt gctactttac agttttgtcc gtttatttgt ataagaaaaa ccttgaaggg
   120961 gcaactcttc aaggttttat actcttagaa aatttcttca aaccgcgtca gctttatctg
   121021 caacctcaaa acagtgtttt gagcagcctg cgactagctt cctagtttgc tctttgattt
   121081 tcattgagct ttaaaatcca gtcagggtaa tccccaatag gcggacacct ctttctttct
   121141 cgcttaattc ttcatagagt tgcagggcta tttggcttat ctgactagca tcttgtgttt
   121201 tttgagcaag actttttcgt ttggtaagag ttgaaaagtc ctcgtagcgg attttcaaaa
   121261 tgacaatttt tccagctttt tcttgttgat gtagattgag agcgactttt tctgatagaa
   121321 tagtcagctc ttttttgata tcttcctcag cacggagaat cttcccgtag gttttctcct
   121381 tgccgattga tttacggatg cgattggatt tgactggaga gttgtgaatg ccacgagcct
   121441 ttcgatacag atcatagcct agtctaccaa aacggtctat tagggtcacc tcaggaactt
   121501 caagtaaatc agcaccagta aaaacgccca tttgatgaag acgttctact gtcttttttc
   121561 ctactccatg aaatttggaa atatccattt gtttgagaaa attctcagcc tgttcaggta
   121621 gaatcactgt caaaccatga ggtttttgat aatcactcgc cattttagct aagaacttgt
   121681 tgtaggaaat accggcagaa gcagttagat ggagttcttg ccagatatct ttttgaatga
   121741 ggcgagcaat tttgaccgct gacttgatac cgagtttatt ttctgtcaca tccaaatagg
   121801 cttcgtcaat gctcatgggt tcaatcaaat ctgtatagcg cttaaaaata gctcgaatct
   121861 ggagtcccac agctttgtat ttctcataat ttcctgagat aaagacggcc tggggacaac
   121921 gttcataagc ttccttggaa ctcatggcag aatggacacc aaaagctcga gcctcatagc
   121981 tacaggtaga aacgactccc cgtccacctg tttgccgagg gtcgcttcca ataatgacag
   122041 gttttcctct gagtttagga ttatccttga tttccaccgc agcaaaaaag gcatccatgt
   122101 caatatggat gatttttctt gacaaatcat ttaacaaagg aaaaatcaac atgcctagca
   122161 cctttttata ctcttcgaaa atctcttcaa accacgtcag ctctatctgc aacctcaaaa
   122221 cagtgttttg agaaatctgc ggctagcttc ctagtttgct tttcgatttc cattgagtgt
   122281 tactgcttat tttcttttat tatacccttt tttctgaaaa aaagaaaaaa ggactttatt
   122341 ttttcaaaaa tataatacag tttgaaataa aatatagact gttttagaaa agaaagtgta
   122401 aaaataggga tttttcactt gttgaaatcg gttactatat ggtatacttg tctcatgaat
   122461 gtaacagatg actgttacta gaaaaaagag gacattaata tggttgttaa gacagttgtt
   122521 gaagcacaag atatttttga caaagcttgg gaaggcttca aaggcgtaga ttggaaagaa
   122581 aaagcaagtg tatcacgctt tgtacaagct aactacacac cttatgatgg agacgaaagc
   122641 ttccttgcag gaccaacaga gcgttcactt cacatcaaga aaattgtaga agaaactaaa
   122701 gcacactacg aagaaactcg tttcccaatg gacactcgtc caacatctat cgctgatatc
   122761 cctgctggat ttatcgacaa agaaaatgaa gttatctttg gtatccaaaa tgatgaactc
   122821 ttcaaattga acttcatgcc aaaaggtggt atccgtatgg ctgaaactac tttaaaagaa
   122881 aatggatacg aaccagaccc agctgttcac gaaatcttca ctaaatatgt aacaacagtt
   122941 aacgacggta ttttccgtgc ctacacttca aatattcgtc gcgctcgtca tgcacacact
   123001 gtaactggtc ttccagatgc atactcacgc ggacgtatca tcggtgttta cgcacgtctt
   123061 gctctttacg gtgcagacta cttgatgcaa gaaaaagtaa acgactggaa tgcaatcaaa
   123121 gaaatcgatg aagaaacaat ccgtcttcgt gaagaagtaa accttcaata ccaagcattg
   123181 caacaagttg ttcgcctggg tgacctttac ggggttgatg ttcgcaaacc agcgatgaac
   123241 gtgaaagaag caatccaatg ggttaacatt gctttcatgg ctgtctgccg tgtgattaac
   123301 ggtgctgcta catctctagg tcgtgtacca atcgtattgg acatctttgc agaacgtgac
   123361 cttgctcgtg gtacatttac tgaatcagaa atccaagaat tcgttgatga tttcgttatg
   123421 aaacttcgta cagttaaatt tgctcgtacc aaagcttatg accaattgta ctcaggtgac
   123481 ccaaccttta tcacaacttc tatggctggt atgggtaacg acggtcgtca ccgtgttact
   123541 aagatggact accgtttctt gaacactctt gacaacatcg gtaactcacc agaaccaaac
   123601 ttgacagttc tttggactga caaattgcca tacaacttcc gtcgctactg tatgcacatg
   123661 agccacaaac actcttctat ccaatacgaa ggtgtaacaa caatggctaa agacggatat
   123721 ggtgaaatga gctgtatctc atgctgtgtg tctccacttg atccagaaaa tgaagaacaa
   123781 cgccacaaca tccagtactt cggtgctcgt gtaaacgttc ttaaagccct tcttactggt
   123841 ttgaatggtg gttacgacga tgttcacaaa gactacaaag tatttgacat cgatcctatt
   123901 cgtgacgaag ttcttgaatt tgaatcagtt aaagcgaact ttgaaaaatc tcttgactgg
   123961 ttgactgaca cttacgtaga tgccttgaac atcatccact acatgactga taagtacaac
   124021 tacgaagctg ttcaaatggc cttcttgcca actaaacaac gtgccaacat gggattcggt
   124081 atttgtggat ttgctaacac tgttgataca ttgtcagcga ttaaatacgc tacagttaaa
   124141 ccaatccgtg atgaagatgg ctacatctac gattacgaaa caatcggtga ctacccacgc
   124201 tggggtgaag atgacccacg ttcaaacgaa ttggcagaat ggttgatcga agcttacaca
   124261 actcgtctac gtagccacaa actatacaaa gacgcagaag ctacagtatc acttttgaca
   124321 atcacatcta acgttgctta ctctaaacaa actggtaact caccagttca caaaggtgta
   124381 tacctcaacg aagatggttc tgtgaacttg tctaaacttg aattcttctc accaggtgct
   124441 aacccatcta acaaagctaa aggtggttgg ttgcaaaact tgaactcact ttctagcctt
   124501 gactttagtt atgcagctga cggtatctca ttgactacac aagtatcacc tcgcgctctt
   124561 ggtaagactc gtgatgaaca agttgataac ttggtaacaa tccttgatgg ttacttcgaa
   124621 aacggtggac aacacgttaa cttgaacgtt atggacttga acgatgttta cgaaaaaatc
   124681 atgtcaggcg aagacgttat cgtacgtatc tctggatact gtgtaaacac taaatacctc
   124741 actccagaac aaaaaactga attgacacaa cgtgtcttcc acgaagttct ttcaatggat
   124801 gacgccttgg atgcattgag ctaatcaagt tcttgaataa taaaaagggc tctttgtcaa
   124861 ctgtagtggg ttgaagaaaa gctaagctcg agaaaggaca aattttgtcc tttctttttt
   124921 gatgttcaga gcgatgaaaa tccgtttttt gaagttttca aagttccgaa aaccaaaggc
   124981 attgcgcttg atgtctttga tgagtttgtt agtggcctca agtttagcgt tagaataagg
   125041 caattcaatg gcgttagtga tgtagttttt atagcgaata aatgtgctca aagtggtttt
   125101 aaaggtgcgg ttgagatgag gtaacgtgtc ttgaattaag ccccaaaact ggtcagtatt
   125161 cttctcttgt agatgaaata ggagtagttg atacaggtca tagtaatctt taagttcagg
   125221 tactagagta aagattttct tcagacactc cctaggagtt aaggtctctc tgaaagttct
   125281 agcatagaaa ggcttaagag agagtttccg actatctttt aggataaatt tccagtaata
   125341 tttaagagct ctgtattcca gagatttatc atcaaattgc ttcatgatgt tgattctagt
   125401 ctgattaaga gccctgctca tgtgttggac aatgtggaaa cgatcgagaa caattttagc
   125461 attgggaaat aatttcttaa tgagagggat ataacttcca gacatatcaa cagtgacgac
   125521 tttaactttt tttctagctt ctttcgagta cttgaagaaa tgatttcgga tggttgtttg
   125581 acgtctgtta tcaagaatgg tcatgatttt cttagtgttg aaatcctgag caatgaaagc
   125641 caatttcccc ttctggtagg agaattcatc ccaggagagg atttcaggca aagtggtgta
   125701 atcctcttgg aaatgaaatt gcttgagctt acgatagacg gtagaggtag aggtagagat
   125761 ggctaattta gaagcgatat gtgtaagagc ctctctgttg agtaggagtt gggcaatttt
   125821 ctgtctcacc atttccgaga tttggcaatt tttctgaacg agagttgttt cagctacagt
   125881 gactttccga caggacttgc attgaaatcg tctctttttc aaatgaatga ggctagggaa
   125941 accaccaatc tcgataaaag ggattttaga aggcttttgg aagtcgtatt tgatttgttt
   126001 tcctttacag tgtttacatt taggtgggtg ataatcaagt gtagcgaaga cttcgatatg
   126061 ggtatcgtgc tgaatggctt tatttaaggt gatgtttttg tcttttattc cgatgagtaa
   126121 tgtggtatga ttgatgtgtt ccataagata ctttctaatg agttgtttag gcgcttttca
   126181 ttataaatct tatgggactt ttttgatact caaaaagccc tataatctcc acagtgggat
   126241 ttacccacta cagaaattat agagccagaa aaaacacttt tgttcactag cagaaactag
   126301 agagcagaag tgtttttctg ttcagattta cccaaaactg ggaaatatgg ggataagaat
   126361 agagatggct taggaagccc ctttttgtgt gtagacagta cgatgaactt ataacaaata
   126421 gtgagccttt ttagcaatca ttgcgacccg tttgtcaaaa gcctcttttc ggatatctac
   126481 aattgtctga tagatgagac gctgttggct aacatgcaaa tctaaggcaa tcgtcaaaaa
   126541 gtgatgtttc cctttgggat actgcttttt aacgtaaggc aggtattctt tcgttgtaat
   126601 aataatcaat ggctctgtca aatgctcctc tgaaggagga ggactaatta gaatattgta
   126661 tcctgtaaca gaggcaactt tgtcagtaaa attccgtaaa ataatggact ttattaagtt
   126721 tacatctgct tgattattta aaatgataaa aatcgggata gcaggtagtg aggaaaagat
   126781 ggtttctgtc aagtagagtg agaaaaggta cagccgatgc tggtcgataa ctccttcaat
   126841 cttctgctca gtcatccact cttgaacaat tgctttcgaa atatgataca gtggcttgtc
   126901 gctttcaatc ccataatgtt cgtaataatt ataataggga actagatttt gtaaaccaaa
   126961 caaaaacgtt cttgttaaga aagtcagtgc tgttaaaaaa gaaagagaat tcgaaatgtc
   127021 atttcctaag atattcttga acttggatag tagatgcttt cctcttgtat gctgaagaat
   127081 cagttgaata gtatgagtct ttttttcttg attccatttg tccttggaaa acgaagaatt
   127141 agcagaacaa taaaccaaaa agatataatc cagttcttcc tgagtaaaag tcatgttggc
   127201 atgtggctct aagtaagttt ggcaatgttc catcaaaatc ggatacataa agaggttttt
   127261 taatttttca aactctttgg actcagggaa ctcaagtgga aattcccgac gtttccaagt
   127321 gagtgccact agtatgctaa aatgaacata ctcgtcaggt gtgatttcta acagttcatg
   127381 actgagttga gaattagact gcacaatcat atgtgtgacc caatccatac ttccatcatt
   127441 caaatcataa atctcaatac caaaatgaaa ctggaggagt gcaattaaaa aacgaatgcg
   127501 atattcagga ccaactactt gatttttcac aaggtccaaa cctactgaac gtagtaacaa
   127561 gccacacttt tgtcgtacgc ggtagcctgt tgcgatggaa atatactctt tttgtgtaaa
   127621 ttcgttaaag ctttgattac cttgtagtag aaagaagcgg agtattttta aaatagttga
   127681 ttggttataa agctgatgga agtaataatt cgtttgatga gaatggtgtt cgattaattg
   127741 aacttgttgc gtatctaaat taaatgtcaa ctcttcctcg aatgtttctt gtaattcctg
   127801 caaaatgctt aggagacttt tagattgtaa tgaagttaaa gtagacagtt catctagttc
   127861 aatagaccga atatccaata atatatttaa aatggtaatt ttatctgtaa ttcttttttc
   127921 aatgtatttg tttagcatag ttaccgaatc ttagttgcat atagataatt ttaattatta
   127981 taatacaaaa gaaactaatt gtcttgtcaa aaaggttgtg gaatttccga ctttattgat
   128041 aaaacagcat gtaataaaag gcattttaaa
//
LOCUS       DAVHSY010000002        94676 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.002, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000002 DAVHSY010000000
VERSION     DAVHSY010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 94676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.002"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(41..376)
                     /locus_tag="VVR43_000128"
     CDS             complement(41..376)
                     /locus_tag="VVR43_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HEU6148551.1"
                     /translation="MNYDAEGEWTALDDIKNEAYMLKKLADKSYTTNLTDEFYIVDDY
                     FLVQEQVDGLNFEEFIRETEYSLNIREKSLDNIVNIVNDIHKLGYKIVDIAPTNFIYT
                     KKMYCPSNS"
     gene            complement(487..729)
                     /locus_tag="VVR43_000129"
     CDS             complement(487..729)
                     /locus_tag="VVR43_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148552.1"
                     /translation="MHSPVHYRYGAFLKKQAYDEKNKKVIYLLLDEKRKNYVEDKRQN
                     FPSLPSWKMDLFSEEEKRIYFQTTCEVSSKDSAINK"
     gene            complement(930..1106)
                     /locus_tag="VVR43_000130"
     CDS             complement(930..1106)
                     /locus_tag="VVR43_000130"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148553.1"
                     /translation="MDLLEKECLKCDKNFQQDDIWNYYHLSDKMPAQGWKIHISSQIK
                     DAVDILRLCINYPN"
     gene            1655..2332
                     /locus_tag="VVR43_000131"
     CDS             1655..2332
                     /locus_tag="VVR43_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU6148554.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            2319..3116
                     /locus_tag="VVR43_000132"
     CDS             2319..3116
                     /locus_tag="VVR43_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU6148555.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSCGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            3133..4236
                     /locus_tag="VVR43_000133"
     CDS             3133..4236
                     /locus_tag="VVR43_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU6148556.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELILDPLNYPIENYVKRVKSE"
     gene            4537..5556
                     /gene="galE"
                     /locus_tag="VVR43_000134"
     CDS             4537..5556
                     /gene="galE"
                     /locus_tag="VVR43_000134"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU6148557.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            5558..6523
                     /locus_tag="VVR43_000135"
     CDS             5558..6523
                     /locus_tag="VVR43_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6148558.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFLYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(6574..6780)
                     /locus_tag="VVR43_000136"
     CDS             complement(6574..6780)
                     /locus_tag="VVR43_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU6148559.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            6832..7308
                     /locus_tag="VVR43_000137"
     CDS             6832..7308
                     /locus_tag="VVR43_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU6148560.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            7317..7988
                     /locus_tag="VVR43_000138"
     CDS             7317..7988
                     /locus_tag="VVR43_000138"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU6148561.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLVVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            8119..8457
                     /locus_tag="VVR43_000139"
     CDS             8119..8457
                     /locus_tag="VVR43_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU6148562.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     ELKSEFVRKI"
     gene            8460..9089
                     /locus_tag="VVR43_000140"
     CDS             8460..9089
                     /locus_tag="VVR43_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU6148563.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            9329..10480
                     /locus_tag="VVR43_000141"
     CDS             9329..10480
                     /locus_tag="VVR43_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6148564.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            10792..11541
                     /gene="truA"
                     /locus_tag="VVR43_000142"
     CDS             10792..11541
                     /gene="truA"
                     /locus_tag="VVR43_000142"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU6148565.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVAADFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            11531..12304
                     /locus_tag="VVR43_000143"
     CDS             11531..12304
                     /locus_tag="VVR43_000143"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU6148566.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNVGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            12282..12743
                     /locus_tag="VVR43_000144"
     CDS             12282..12743
                     /locus_tag="VVR43_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6148567.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNDWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            12974..14315
                     /locus_tag="VVR43_000145"
                     /pseudo
     CDS             12974..14315
                     /locus_tag="VVR43_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(14443..14646)
                     /locus_tag="VVR43_000146"
     CDS             complement(14443..14646)
                     /locus_tag="VVR43_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6148568.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(14639..15721)
                     /locus_tag="VVR43_000147"
     CDS             complement(14639..15721)
                     /locus_tag="VVR43_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU6148569.1"
                     /translation="MSKLQQILIYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYYGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(15847..16629)
                     /locus_tag="VVR43_000148"
     CDS             complement(15847..16629)
                     /locus_tag="VVR43_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU6148570.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(16629..17972)
                     /locus_tag="VVR43_000149"
     CDS             complement(16629..17972)
                     /locus_tag="VVR43_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU6148571.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILEAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(18071..19387)
                     /locus_tag="VVR43_000150"
     CDS             complement(18071..19387)
                     /locus_tag="VVR43_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU6148572.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            19580..20806
                     /locus_tag="VVR43_000151"
     CDS             19580..20806
                     /locus_tag="VVR43_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU6148573.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            21005..22579
                     /locus_tag="VVR43_000152"
     CDS             21005..22579
                     /locus_tag="VVR43_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6148574.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LNEKQTGFVIRNKGDK"
     gene            22844..23632
                     /gene="codY"
                     /locus_tag="VVR43_000153"
     CDS             22844..23632
                     /gene="codY"
                     /locus_tag="VVR43_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU6148575.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            23632..24207
                     /locus_tag="VVR43_000154"
     CDS             23632..24207
                     /locus_tag="VVR43_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU6148576.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            24289..24374
                     /locus_tag="VVR43_000155"
     tRNA            24289..24374
                     /locus_tag="VVR43_000155"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:24323..24325,aa:Leu,seq:aag)
     gene            24658..25788
                     /gene="ugpC"
                     /locus_tag="VVR43_000156"
     CDS             24658..25788
                     /gene="ugpC"
                     /locus_tag="VVR43_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU6148577.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(25935..26081)
                     /locus_tag="VVR43_000157"
     CDS             complement(25935..26081)
                     /locus_tag="VVR43_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148578.1"
                     /translation="MEIKEKTRKLAVSCSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEY"
     gene            26289..27047
                     /locus_tag="VVR43_000158"
     CDS             26289..27047
                     /locus_tag="VVR43_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU6148579.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAIDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            27134..27646
                     /locus_tag="VVR43_000159"
     CDS             27134..27646
                     /locus_tag="VVR43_000159"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU6148580.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            27828..28772
                     /locus_tag="VVR43_000160"
     CDS             27828..28772
                     /locus_tag="VVR43_000160"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU6148581.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWINHAVYQETPFDWRKIEDDASAYGYL"
     gene            28781..29458
                     /locus_tag="VVR43_000161"
     CDS             28781..29458
                     /locus_tag="VVR43_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU6148582.1"
                     /translation="MTYLDAFKSGILVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            29557..30315
                     /locus_tag="VVR43_000162"
     CDS             29557..30315
                     /locus_tag="VVR43_000162"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU6148583.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            30353..31858
                     /gene="lytC"
                     /locus_tag="VVR43_000163"
     CDS             30353..31858
                     /gene="lytC"
                     /locus_tag="VVR43_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEU6148584.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGVYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            32355..32873
                     /locus_tag="VVR43_000164"
     CDS             32355..32873
                     /locus_tag="VVR43_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU6148585.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLITLFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            33005..33511
                     /locus_tag="VVR43_000165"
     CDS             33005..33511
                     /locus_tag="VVR43_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU6148586.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWYLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNSEEKIDGVTTFYDVQSVLDWYHAQDKNLYILGG
                     KQVFQAFEPYLDEVIVTQIHARVEGDTYFPEEFDLSLFETVSSKSFTKDEKNPYDFTI
                     QYRKRKEV"
     gene            33511..33681
                     /locus_tag="VVR43_000166"
     CDS             33511..33681
                     /locus_tag="VVR43_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148587.1"
                     /translation="MERSIFGFFTAMLCLVCLLAGAQAFRKKRYGLSVLLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            33718..34950
                     /gene="clpX"
                     /locus_tag="VVR43_000167"
     CDS             33718..34950
                     /gene="clpX"
                     /locus_tag="VVR43_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU6148588.1"
                     /translation="MPTTRNNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQE
                     IIREELAEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELKFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            34959..35546
                     /locus_tag="VVR43_000168"
     CDS             34959..35546
                     /locus_tag="VVR43_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU6148589.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            35557..35937
                     /locus_tag="VVR43_000169"
     CDS             35557..35937
                     /locus_tag="VVR43_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU6148590.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            35989..36879
                     /gene="rapZ"
                     /locus_tag="VVR43_000170"
     CDS             35989..36879
                     /gene="rapZ"
                     /locus_tag="VVR43_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU6148591.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            36876..37853
                     /locus_tag="VVR43_000171"
     CDS             36876..37853
                     /locus_tag="VVR43_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU6148592.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            37850..38761
                     /gene="whiA"
                     /locus_tag="VVR43_000172"
     CDS             37850..38761
                     /gene="whiA"
                     /locus_tag="VVR43_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU6148593.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(38795..39763)
                     /locus_tag="VVR43_000173"
     CDS             complement(38795..39763)
                     /locus_tag="VVR43_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU6148594.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLNLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            39899..40756
                     /locus_tag="VVR43_000174"
     CDS             39899..40756
                     /locus_tag="VVR43_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU6148595.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            40743..41522
                     /locus_tag="VVR43_000175"
     CDS             40743..41522
                     /locus_tag="VVR43_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEU6148596.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            41546..42898
                     /locus_tag="VVR43_000176"
     CDS             41546..42898
                     /locus_tag="VVR43_000176"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU6148597.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            42972..43346
                     /locus_tag="VVR43_000177"
     CDS             42972..43346
                     /locus_tag="VVR43_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU6148598.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            43348..44196
                     /locus_tag="VVR43_000178"
     CDS             43348..44196
                     /locus_tag="VVR43_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU6148599.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            44473..45240
                     /locus_tag="VVR43_000179"
     CDS             44473..45240
                     /locus_tag="VVR43_000179"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU6148600.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            45252..46436
                     /locus_tag="VVR43_000180"
     CDS             45252..46436
                     /locus_tag="VVR43_000180"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU6148601.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSLLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            46433..48304
                     /locus_tag="VVR43_000181"
     CDS             46433..48304
                     /locus_tag="VVR43_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6148602.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(48447..49631)
                     /gene="mntE"
                     /locus_tag="VVR43_000182"
     CDS             complement(48447..49631)
                     /gene="mntE"
                     /locus_tag="VVR43_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU6148603.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            49935..52631
                     /locus_tag="VVR43_000183"
     CDS             49935..52631
                     /locus_tag="VVR43_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU6148604.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            52644..53435
                     /gene="yghU"
                     /locus_tag="VVR43_000184"
     CDS             52644..53435
                     /gene="yghU"
                     /locus_tag="VVR43_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU6148605.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            53551..53961
                     /locus_tag="VVR43_000185"
     CDS             53551..53961
                     /locus_tag="VVR43_000185"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU6148606.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            53973..55568
                     /locus_tag="VVR43_000186"
     CDS             53973..55568
                     /locus_tag="VVR43_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148607.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            55634..55798
                     /locus_tag="VVR43_000187"
     CDS             55634..55798
                     /locus_tag="VVR43_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU6148608.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            55877..56605
                     /gene="yaaA"
                     /locus_tag="VVR43_000188"
     CDS             55877..56605
                     /gene="yaaA"
                     /locus_tag="VVR43_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU6148609.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(56656..58140)
                     /locus_tag="VVR43_000189"
     CDS             complement(56656..58140)
                     /locus_tag="VVR43_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6148610.1"
                     /translation="MRNLLSTKVQRQLRLMENLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYIPGITKKFICRNHLSIINLVNHLNTLSNEIHLSNTL"
     gene            58356..63977
                     /locus_tag="VVR43_000190"
     CDS             58356..63977
                     /locus_tag="VVR43_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEU6148611.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKLAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASINEILKPGLSLSDARQNPAIRKEDLDK
                     GYSGFRAAPAPTNKLVTNLGNNTVFTDISRGSHTFRGNGNSRGGNPIHFDVTTTRVGN
                     RVEFSIAYSGPGEFVNNNFLLDKGNGFGEPSRATISTNRLRDQTKDIRKGANFVSHSS
                     YSLTSAVETNSNQTIRFSLPIANPNGDLSVRLRPVTFNVGQGESGSATSNDPYSNSNY
                     YFREKPLLLDANPNGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEKGQRQIIY
                     KVHQLGNETILGLPISNSVIKEVKPRIMQIGVAKDLIDTVKPRVDQNKVGDTNNLTFY
                     LDNDGNGVYTEGVDELVQKIAIKDGAKGEKGVQGERGLTGAQGQAGRDGVTPTVTVKD
                     NKNDGTHTITINDGRGNVASTVVRDGFDGASPLVATQRNEADKTTTVIFYYDQNGNNE
                     LDASDKKLKEVIIADGAKGEQGLQGRDGAQGPKGEQGNPGTPGKDGKSLIAVKNGTET
                     KVYVEDPARPGQPLNPNQPLATITDGRNGTNGQSPTITATRSVQNGKNGVLVTITPVG
                     GRPQTTFVEDGQKGADGKTPTVTITEGQNGTHTLTVHNPGSPDVTTTIRDGATGQAGR
                     DGKDVLNGKVNPQPNQGKNGDKYINTETGDVYVKNNGNWDKEGNIKGPKGDKGADGAK
                     GEKGDQGERGLTGAQGAKGADGAVGRDGRDGKDVLNGKANPEAHQGKDGDKYVNTETG
                     DVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDGHSTDITFTVPGKDPV
                     TVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDGKYTPGTDELLGSE
                     MIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPLAVIRDGVDGKSP
                     TVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGAIGQDGQTPTITTQRGQ
                     DGQSTVVTITTPGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRIRRATDAAATPTR
                     NGIRVTVYDDVNDNGVYDGGVDKVLNSKDIYNGIDGRDGSAPTITTKDNGDGTHTITV
                     QNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKETVVKNGKDGKTP
                     KVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPDGSHTVTITNPDG
                     TKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETTVRDGKSPKVTIT
                     DEQNGTHKISVLNGDGTTTETIIKDGKSPVATVRDNQDGTYTIRVENGNGTVSETTVR
                     DGKSPTAKVVDNGDGTHTITVVNSDGTTTTTTVRYGREPKLEVIDNNDGSHTIKVTGA
                     DGKETTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDGVSPTVT
                     VENNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGTVT
                     KTVIKDGKDGRDGRDGRDGKDGKCGCQDKPVTPSNDKPVPPAPNVPTPEVLVKPVPAQ
                     PTPNVPTPEVPVQPTPAVPTPEVPVPEQPVVPTPAQPATPVNANPVAPTTGKENRGDK
                     LPETGSQSDYISVLLGSGILLSLYVGRRKED"
     gene            complement(64214..64762)
                     /locus_tag="VVR43_000191"
     CDS             complement(64214..64762)
                     /locus_tag="VVR43_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU6148612.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGASALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            65083..65571
                     /locus_tag="VVR43_000192"
     CDS             65083..65571
                     /locus_tag="VVR43_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU6148613.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            65568..66755
                     /locus_tag="VVR43_000193"
     CDS             65568..66755
                     /locus_tag="VVR43_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6148614.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEVA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEESEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            66748..66972
                     /locus_tag="VVR43_000194"
     CDS             66748..66972
                     /locus_tag="VVR43_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU6148615.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEV"
     gene            67129..68475
                     /gene="asnS"
                     /locus_tag="VVR43_000195"
     CDS             67129..68475
                     /gene="asnS"
                     /locus_tag="VVR43_000195"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU6148616.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            68628..68918
                     /locus_tag="VVR43_000196"
     CDS             68628..68918
                     /locus_tag="VVR43_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU6148617.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            68930..69400
                     /gene="ssbA"
                     /locus_tag="VVR43_000197"
     CDS             68930..69400
                     /gene="ssbA"
                     /locus_tag="VVR43_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU6148618.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            69432..69671
                     /locus_tag="VVR43_000198"
     CDS             69432..69671
                     /locus_tag="VVR43_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU6148619.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            69966..71366
                     /locus_tag="VVR43_000199"
     CDS             69966..71366
                     /locus_tag="VVR43_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU6148620.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIGKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            71368..71727
                     /locus_tag="VVR43_000200"
     CDS             71368..71727
                     /locus_tag="VVR43_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU6148621.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHYLKKKK"
     gene            71781..72530
                     /locus_tag="VVR43_000201"
     CDS             71781..72530
                     /locus_tag="VVR43_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU6148622.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPHSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            72520..72819
                     /locus_tag="VVR43_000202"
     CDS             72520..72819
                     /locus_tag="VVR43_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU6148623.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            72890..73825
                     /locus_tag="VVR43_000203"
     CDS             72890..73825
                     /locus_tag="VVR43_000203"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU6148624.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            73912..74424
                     /locus_tag="VVR43_000204"
     CDS             73912..74424
                     /locus_tag="VVR43_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU6148625.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAAFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERDLHDSDF"
     gene            74449..75057
                     /locus_tag="VVR43_000205"
     CDS             74449..75057
                     /locus_tag="VVR43_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEU6148626.1"
                     /translation="MFGELIRYLDQYEDVILREIKSQFPDVAVDKLMEEYIKASLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDRKYELAIDFDKERLTFYLA"
     gene            75158..75352
                     /locus_tag="VVR43_000206"
     CDS             75158..75352
                     /locus_tag="VVR43_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU6148627.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(75398..76843)
                     /locus_tag="VVR43_000207"
     CDS             complement(75398..76843)
                     /locus_tag="VVR43_000207"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU6148628.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKILAFTGTKGKTTAAYFAYNILSQRYPTALLSTMNTTLDGTTFFKSSFS
                     TPENIDLFDMMAQAVKNGRSHLVMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            76949..78571
                     /locus_tag="VVR43_000208"
     CDS             76949..78571
                     /locus_tag="VVR43_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU6148629.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            78772..80733
                     /locus_tag="VVR43_000209"
     CDS             78772..80733
                     /locus_tag="VVR43_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6148630.1"
                     /translation="MKKSKSKYLTLAGFVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRATTNDIVTNLVDGLMENDQYGNYVPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGI
                     KALDDQTVQYTLARPEPYWNSKTTSTILFPVNADFLKSKGDDFGKVDPANILYSGPFL
                     MKAFVSKSVIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQDALVRNFTDGAYSYARLYP
                     NSSSFEGIKEKYKDDIIYSMQDATSYYWNFNLDRQAYKFTSKTTDIEKKSTQEAVLNK
                     NFRQAINFAYDRTSYGAQTQGEDGATKILRNLVVPPTFVSIKGKDFGEVVASKMVNNY
                     GKEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDATVDQASKKGIQE
                     VSSMKQSIEAALGTENVVIDIQQLSTEDYDNSSYLAQTAIQKDYDLYNGGWSPDYLDP
                     STYLDIFSVKNGGVLQNLGLDPGEANDKAKAVGLDTYTQMLEEANKEQDPAKRYEKYA
                     DIQAWLIDSSLAIPNVSLGGTPSLRKTVPFSAPYSLAGNKGVESYKYLKVQDKIVTTD
                     EYAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            80905..81138
                     /locus_tag="VVR43_000210"
     CDS             80905..81138
                     /locus_tag="VVR43_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEU6148631.1"
                     /translation="MKLKLLRVDTKVIMWSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKR"
     gene            81144..82586
                     /locus_tag="VVR43_000211"
     CDS             81144..82586
                     /locus_tag="VVR43_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6148632.1"
                     /translation="MRKKVIEGLIYAEKSFFDKSQSGELTSAIVNDMSVIREFLITTF
                     PNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMMFIILPLSNISEKYSRRLQEEIG
                     FLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSFETPFALLFI
                     FATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTIYSSSKGSSVA
                     LENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPS
                     GSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDN
                     LCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIART
                     YLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDCIFFLE
                     EGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            82744..83838
                     /locus_tag="VVR43_000212"
     CDS             82744..83838
                     /locus_tag="VVR43_000212"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU6148633.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            83846..85012
                     /locus_tag="VVR43_000213"
     CDS             83846..85012
                     /locus_tag="VVR43_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6148634.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVMDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            85105..88203
                     /locus_tag="VVR43_000214"
     CDS             85105..88203
                     /locus_tag="VVR43_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6148635.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKFGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            88251..88868
                     /locus_tag="VVR43_000215"
     CDS             88251..88868
                     /locus_tag="VVR43_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU6148636.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            88879..90213
                     /locus_tag="VVR43_000216"
     CDS             88879..90213
                     /locus_tag="VVR43_000216"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU6148637.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            90223..90687
                     /locus_tag="VVR43_000217"
     CDS             90223..90687
                     /locus_tag="VVR43_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6148638.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            90684..91178
                     /locus_tag="VVR43_000218"
     CDS             90684..91178
                     /locus_tag="VVR43_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6148639.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            91259..92914
                     /gene="mltG"
                     /locus_tag="VVR43_000219"
     CDS             91259..92914
                     /gene="mltG"
                     /locus_tag="VVR43_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU6148640.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADESQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATEIVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDKIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            92985..93467
                     /gene="greA"
                     /locus_tag="VVR43_000220"
     CDS             92985..93467
                     /gene="greA"
                     /locus_tag="VVR43_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU6148641.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(93593..93673)
                     /locus_tag="VVR43_000221"
                     /pseudo
     CDS             complement(93593..93673)
                     /locus_tag="VVR43_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            93795..94193
                     /locus_tag="VVR43_000222"
     CDS             93795..94193
                     /locus_tag="VVR43_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6148642.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT        28547 a        17486 c        21215 g        27428 t
ORIGIN      
        1 tgtgcaatac agaactaaat cctttggata aattatttgt ctaactgttt gaggggcagt
       61 acattttttt ggtgtatata aaatttgtag gagctatatc tacaatttta tatcccagtt
      121 tatggatgtc atttactata ttcacaatgt tgtccagtga tttttctcta atatttaagg
      181 agtattctgt ttctcgaata aattcttcaa agtttaaccc gtcaacttgt tcctgaacaa
      241 gaaaataatc atccacgata taaaattcat cagttaaatt agtagtataa cttttatcgg
      301 ctaatttttt tagcatgtaa gcctcatttt ttatatcatc aagtgctgtc cattctcctt
      361 cggcatcata attcacaaaa ggtcttgact gcttgatgat tactttttgc tcgtccgatt
      421 ttctaattgc ccgataaaca tttcctttat ttgatctctt aataattttt tctattttgt
      481 atttatttat ttatttattg cagagtcctt acttgaaact tcacatgtgg tttgaaaata
      541 aatccttttt tcttcttctg aaaataaatc cattttccag ctaggaagac tagggaaatt
      601 ttgtctctta tcttctacat agttcttcct tttttcatct agcaataaat agatgacttt
      661 tttatttttt tcatcataag cttgtttttt taaaaaagcc ccatatctat aatgaactgg
      721 agaatgcatt ccacattgat agtcagatag tatttttgga gccttaaatt ctgacagttt
      781 attcgtaaga ttacaaatca tactcttggc ttcagattct gacttaggat atagagttat
      841 aaatttgtta gcagtagggt tcatttccct aggggaatga atttttttta attcctctaa
      901 atttttaacg actttaaagc tacaattatt tagtttggat agtttataca caatcttaaa
      961 atatctacag catctttgat ttgagaactt atgtgtattt tccagccttg tgcaggcatc
     1021 ttatctgaca aatgatagta attccaaata tcatcttgtt ggaaattttt atcacatttt
     1081 aaacattctt tctctaataa atccataaca aactcctaat tattaaaata ggctagagac
     1141 acagcactag cctattccgt aagtaaagct acttatttta tataaaatat aactagcgac
     1201 ctgtaattaa acaagtaaaa gaacaatact tagggagacc tgtgacaatg atatcttcct
     1261 ctggaagtag ttctaattca aacaatgttt gttccatgac tgtatcctcc tgttatgata
     1321 aattccagaa agcatagagc aaattcgtgg ttcgtctgac taaatttctt atctgaacac
     1381 caccttcaaa tacaaatttt agtcaaactt ttattttttc taactttcta attatattct
     1441 accatgtgtt tttatatgtc aagaattttc tgaataaact gtttattttt tattttttga
     1501 catttttgca aattgtttaa aatctttcaa ttggattcac ttattacttt aggacattga
     1561 aacttctttc gccagaggtg cttatattac tgggaagttg aagattgaaa tgtggtataa
     1621 taagaggtaa tagagttttg gaaagtgaga gaagatgatt tcaaagagat tagaattggt
     1681 agcttccttt gtgtcacagg gggctatttt actagatgtg ggaagtgacc atgcttatct
     1741 gcctatcgag ttggttgaga gaggccaaat caaaagcgct attgcaggtg aggtggtgga
     1801 aggtccctat cagtctgcgg ttaaaaatgt tgaggctcac ggcctaaagg agaaaatcca
     1861 agtccgttta gccaatggct tggcagcttt tgaagagact gaccaagtgt ctgtcattac
     1921 cattgctggc atgggtggtc gtttgattgc taggatttta gaagaaggtt tggggaagtt
     1981 agctaatgta gagcgtttga tcctccagcc caataatcgt gaagacgact tgcgtatctg
     2041 gctacaggat catggattcc agattgtagc agaaagcatc ttagaagaag ctggaaagtt
     2101 ttatgagatt ttggtggtgg aagcaggaca aatgaagcta tcagccagtg atgttcgctt
     2161 tggtcccttc ttgtccaaag aagtcagtcc agtatttgtc caaaaatggc aaaaagaagc
     2221 tgagaagcta gagttcgccc tcggacaaat cccagaaaaa aatctggaag aacgtcaagt
     2281 tctagtagat aagattcaag ctatcaagga ggtgctccat gttagcaagt gaagtgatcc
     2341 aagcttatga agccttttgc cctcaggaat tttctatgga gggagacagc tgtggtctgc
     2401 aaattggcac tttagacaag ggtatccaaa gggtcatggt tgccctcgat attcgtgaag
     2461 agacggtggc agaggccatt gaaaagggtg tggacttgat tatcgtcaag cacgcgccta
     2521 tctttcgtcc tatcaaggac ttgcttgcca gccgtccgca aaatcagatt tacatcgacc
     2581 tgattaagca tgatatcgca gtttatgtca gccataccaa tattgatatc gttgaaaatg
     2641 ggctcaatga ctggttttgt cagatgctag gaatcgagga gacgacttat ctgcaggaaa
     2701 caggtccaga acgtggaatt ggacgtattg ggaatattca gcctcagaca ttttgggaat
     2761 tggcccaaca ggtcaagcaa gtctttgacc tagatagcct tcgaatggtg cattatcaag
     2821 agaatgattt gcagaagcct atttcaagag tagcaatttg tggtggaagc gggcagtctt
     2881 tctataagga tgctttggca aagggggcag atgtctatat cactggtgat atctactacc
     2941 atactgctca ggatatgctg tctgatggct tgttagcatt ggatccaggt cactatatcg
     3001 aagtgctttt tgtggaaaaa atcgcagcac tccttactca atggaaagag aaaaaaggct
     3061 gggaactaga gattttacct agtcaagcat cgaccaatcc tttccgtcat atctagttag
     3121 aaagtgaaga caatgaaaaa agttgccatt attggagcag gaattgtggg agcaacagct
     3181 gcctactacc tctcgagaga aagtgaccta gaggtgaccg tttttgacca tgagcaaggt
     3241 caagccacca aggccgcagc aggaattatc agtccttggt tttccaaacg ccgtaataaa
     3301 gcctggtaca agatggcgcg cttgggggct gacttttatg tggatttatt agctgattta
     3361 gagaaatcag gacaaaaaat cgacttttac cagcgttcgg gagtctttct cttgaaaaag
     3421 gatgaatcca agttggaaga actttatcaa ctggccctcc agcgcagaga agaatctccc
     3481 ttgatagggc aattagccat tctggaccaa gcttcagcta atgaattatt ccctggtttg
     3541 cagggatttg accgcctgct ctatgcttct ggtggagcga gagtagatgg ccaactcttg
     3601 gtaactcgtc tgctagaagc cagtcatgtc aagctggtca aagaaaaagt gactctgaca
     3661 ctcttatcat caggctacca gattggcgaa gaggtgtttg atcaggttat tttggcaacg
     3721 ggagcttggt tgggggacat gttagagcct ttaggttatg aagtggatgt ccgtcctcaa
     3781 aaaggacaac tacgggatta tcagcttgcc caagacatgg aagattaccc tgttgtcatg
     3841 ccagaagggg agtgggattt gattcctttt gcaggtggga aattgtcctt aggcgctacc
     3901 cacgaaaatg acatgggatt tgatttgacg gtagatgaaa ccttgctcca acaaatggag
     3961 gaggccacct tgactcacta tctgattttg gctgaagcta cttcaaaatc tgagcgtgtg
     4021 ggaatccgtg cctataccag tgatttctct cccttctttg ggcaggtgcc agaattggca
     4081 ggtgtctatg cagccagtgg actaggttca tcaggcctca caactggtcc tatcattggt
     4141 taccatctag cccaactgat ccaagacaag gagttgatct tggaccctct aaattaccca
     4201 attgaaaact atgtcaaacg agtaaaaagc gaataatact caatgaaaat caaagaacaa
     4261 actaggtaac tagccgcggg ttactcaaag cactgctttg aggttgtgga tagaactgac
     4321 gaagtcagct caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat
     4381 acccatggca aggcgacgtt gacgtggttt gaattggatt ttcgaagagt ataagcattt
     4441 tactgaaatt ttatcaggta gtttaggatg gcaaatgaca ttccctgtca aaaatggtaa
     4501 aataagaaaa aataatctga gaatcgagga aaaaagatgc aagaaaagat tttggtaact
     4561 ggtggtgccg gttttattgg aacccacact gttattgaat tgatccaagc aggccatcaa
     4621 gttgttgtgg tggataatct tgtcaatagc aatcgtaaga gtttagaagt tgttgaaaga
     4681 atcacaggag ttgagattcc tttctatgag gcagatattc gtgacacagc taccctcaga
     4741 gatattttca agcaggaaga accgactggt gtcattcact ttgctggttt gaaggctgtt
     4801 ggcgaatcaa cacgtatccc tcttgcctac tatgacaaca atatcgctgg aactgtcagc
     4861 cttttgaaag ccatggaaga aaacaactgt aaaaacatca tcttcagttc ttctgcgaca
     4921 gtttacgggg atccgcacac agtgcccatc ttggaagatt tcccactttc agtgaccaac
     4981 ccatacggtc gtactaagct catgctagag gaaattttga ctgatattta caaagcagac
     5041 tcagaatgga atgttgtctt gcttcgttac tttaacccaa tcggagccca tgagagtggt
     5101 gatttgggag aaaatccaaa cggtattcca aacaatctct tgccatatgt gactcaagta
     5161 gccgttggaa aattagagca agtgcaagtg tttggagacg attacgatac ggaagatgga
     5221 acaggtgttc gtgactatat ccacgttgtc gatttggcta agggtcacgt tgcagctttg
     5281 aaaaaaatcc aaaaaggttc aggactaaac gtttataacc ttggaactgg taaaggttac
     5341 tcagttcttg aaattatcca aaacatggaa aaagcggtgg gacgtcctat tccttaccgt
     5401 atcgtagaac gtcgcccagg tgatatcgct gcctgctact cagacccagc aaaagctaaa
     5461 gcagaactcg gttgggaagc agaactcgac atcacccaaa tgtgtgaaga cgcatggcgt
     5521 tggcaaagca agcatccaaa tggatttgaa gactaagatg atgatttcaa tcatcgtccc
     5581 ttgtttaaac gaagaggaag tacttcctct tttttatcag gctctggaag ctttacttcc
     5641 agatttggaa acagaaatcg agtatgtctt tgtcgatgat ggatcaagtg atgggacctt
     5701 ggaactctta aaggcctatc gggagcaaaa tccggcagtc cattatattt ctttctctcg
     5761 aaattttggc aaagaagcag ccctttatgc aggcttgcaa tatgcgacag gagatttggt
     5821 ggtggtgatg gatgcagacc tccaagatcc tcctagtatg ttgtttgaga tgaaaaatgt
     5881 actagacaaa aatgtagact tggactgcgt tgggacacgg agaactagtc gggagggaga
     5941 acccttcttt cgcagtttct gtgctgttct cttttatcgc ctcatgcaaa aaatcagccc
     6001 agtggctctg ccgtcgggtg tccgtgattt tcgtatgatg agaaggtctg tagtcgatgc
     6061 cattttaagc ttgaccgagt ccaatcgttt ttcaaagggg ctcttcgcct gggtgggttt
     6121 caaaacctac tatttggact atccaaatgt cgaaaggcag gctggcaaga caagttggag
     6181 ttttaggcaa ctctttttat actccattga agggattatt aatttttcag attttccctt
     6241 gattatagcc tttgtagctg gtctcctatc ttgttttctt tctctgctga tgaccttttt
     6301 tgttgtggtt cggaccctca ttttgggcaa tccgacatct ggttggacct ctctgatggc
     6361 tgttattctc tttcttggag gcattcaact cttgaccatt gggattctcg gcaagtatat
     6421 cagtaagatt tatttagaga ctaaaaaaag accactttat cttatcaaag aaaaaagtga
     6481 ccttcctgat tttacagaaa aaaataaagt gaaaagacta taattttaca tggaaatgtg
     6541 ctaaactaga gggagtggat tatcgccatt gatttaggct tcctggtttc caatcagggc
     6601 gcgagttggg caatttttaa cagcctctaa gacatcctga ctaggagaaa tttctttttc
     6661 cagttggtca gggtcatcgt aaaaacgcac gattccatta tcgtggtaat caaataaatc
     6721 agaataagtt tggcaaagcc cacaggcgat acatcgttca ggtataagtg tgattttcat
     6781 gttcatattt atattgtaat aagaaaagta aaaaaaaaca aggagtaagg tatggcaaaa
     6841 gaaccgtggc aagaagatat ctatgatcaa gaagaatcaa gagcagagcg tcggcatcga
     6901 aaccacggag gggctgatag gatggctaat cgtattttga cgatcctagc tagtattttc
     6961 tttgtaattg tggtggtgat ggtcatcgtt ctcatctatc tatcatcggg ggggagtaat
     7021 cgcacagcag ccttaaaaga ctttcatgat tctgatgcaa gtgtagtaca aatctcatct
     7081 tcaagcagtt ctcagcctga gcagagttca gagccagaat ctacttctag tagttcagaa
     7141 gaagctgcta atcctgaagg aacgattaaa gttctcgcag gagaagggga agcagctatt
     7201 gccgctcgtg caggaatctc cattgctcag ttagaggcct tgaatcctgg gcacatggct
     7261 acaggatctt ggtttgctaa tccaggtgat gttataaaaa taaaatagga gccgatatga
     7321 aaacaattca aattgctatt gatggtcctg cttccagcgg taagagtacg gtcgcaaaga
     7381 ttattgctaa ggattttgga ttcacctacc ttgatacagg agctatgtat cgtgcagcga
     7441 cctatatggc tcttaagaac caattagtag ttgaagaagt cgaagccctt ctagccttgt
     7501 tggaccagca tccaatcagc tttggacgtt cagaaactgg agaccagctt gtttttgtag
     7561 gagatgtgga tattacccat cctatccgtg aaaatgaagt gaccaatcat gtttctgcta
     7621 ttgcagcaat tcctgaagtg cgtgagaaac tggtttctct ccaacaagaa attgcccagc
     7681 aaggcgggat tgtcatggat ggtcgcgata ttggaactgt tgtattgcca caagcagaat
     7741 tgaaaatttt cctagtagct tctgttgatg agagagcaga gcgtcgttac aaggaaaata
     7801 ttgccaaggg aattgaaaca gaccttgaaa ccctaaaaaa ggaaattgct gcgcgtgact
     7861 acaaggatag tcatcgtgag acttctcctc tcaaacaagc agaggatgct gtctaccttg
     7921 atacaactgg tttgaacatt caagaagtag ttgaaaaaat caaagcagaa gctgaaaaaa
     7981 gaatgtaaat gtagaaaagc cgatagattg atatcggttt ttttctaaat ttgtcaaaat
     8041 gatgatttta gggtataata gttgctgttc gagaaatttt gattttcaaa gaatagtgaa
     8101 tgatgataag gagaaaccat gaacaattta ccaaattgtc caaaatgtaa ctcagagtat
     8161 gtctacgaag acggtgccct actggtttgc ccagagtgtg ctcatgagtg gaatcctgct
     8221 gaagttgcag aagtagaaga aggtcttgtc gctatcgatg ccaacggaaa taaattgact
     8281 gatggtgata cagtaactct catcaaggac ttgaaagtaa aaggtgcgcc aaaagatttg
     8341 aaacaaggga cgcgcgtgaa aaatatccgc atcgtagaag gcgaccacaa tatcgactgt
     8401 aagattgatg gttttggtgc catggaactt aaatcagagt ttgtgaggaa gatttaagca
     8461 tgtcaaaaca ctataaactt gtattttata gccgtatctt cttgtttcta gcggctttta
     8521 cgggagttta tcttgaaatt actaagcatg gtggttttgg gatgcttctc tattacacgg
     8581 ttctgtccaa cctcttggta actattttta ccctttatct tctaaaggtt atgagccgtg
     8641 taggtgaaaa ttggcaaagg ccaagtctct tgcgcttaaa aggtggggtc accatgagta
     8701 tcatgattac ctgtgtgatt taccatttcc tcttggcgcc cattgcgact aatttctata
     8761 ccctagaaaa tttcctttgc cactatatcg ttcccatctg gtttttagcg gataccctct
     8821 tttttgacaa acagggtcaa tacaagattt gggatccagc agtgtggacc attttaccct
     8881 ttctgtatat gatgtttgct ctttttaatg gcttggttct aaaactcaat attccaaatg
     8941 ctaaggataa tcctttccct tacttctttt tgaatgtgaa caagggttgg aatgttgtgt
     9001 ttaagtggtg tctgattatc tttgttgcct atatggtagc aggatttatt ttctacttta
     9061 tcaagcaaat caagagaaag tcatcctaat actcttcgaa aatctcttca aaccacgtca
     9121 gtttccatct gcaacctcaa aacactgttt tgaacaacct gcggctagct tcctagtttg
     9181 ctctttgatt ttcattgagt ataagataca agggattcat tttcgaattt aagaaggagt
     9241 ctacaaacca atgaggcttc ttcttttctt gcttatttga taactatcaa aaaagtagaa
     9301 gattaagaga aatatagaaa gagatttcat gaaacaattt ttagaacggg ccagcatttt
     9361 ggctctctcc ctcgttttga ttacctcctt ttccatttcg agtgccctac cagccatgtt
     9421 tgactattat cagggttatt ctaaggaaca aattgagctc ttggtgagct tgccttcctt
     9481 tggaatcatg atgatgttac tgctaaatgg tttcttagaa aaaatatttc ctgagcgctt
     9541 acagattagt ttgggcttgc tgattttatc attgagcggt acagctccct tctggtacca
     9601 agcctatccc tttgtctttg gaacacggct tctctttggt ttgggtcttg ggatgatcaa
     9661 tgccaaggcc atttctatta tcagtgaacg ctaccaagga aaaaggcgaa ttcagatgtt
     9721 agggctacgc gcttctgcag aggtcgttgg agcttctctc attaccttgg ccgtcggtca
     9781 gttgttggcc tttggttgga cagctatctt tctagcctat agtgctggat ttttggtgct
     9841 gcccctttat ctgctctttg tcccttatgg aaaatcaaag aaagaagtca agaaaagagc
     9901 gaaggaagca agtcgtttaa ctcgagaaat gaaaggcttg atttttacct tagctatcga
     9961 agcggcagtt gtagtttgta ccaatacagc tattaccatc cgtattccaa gtttgatggt
    10021 ggaaagagga ttgggggatg cccagttatc tagttttgtt cttagtatca tgcagttgat
    10081 cgggattgtg gctggggtga gtttttcttt cttgatttct atctttaaag agaaactgct
    10141 cctctggtct ggtattacct ttggcttggg gcaaatcgtg attgccttgt cttcatcctt
    10201 gtgggtggta gtagcaggaa gtgttctggc tggatttgcc tatagtgtag tcttgacgac
    10261 ggtctttcaa cttgtctctg aacgaattcc agctaaactc ctcaatcaag caacttcatt
    10321 tgctgtatta ggctgtagtt tcggagcctt tacgacccca ttcgttctag gtgcaattgg
    10381 cttactaact cacaatggga tgttggtctt tagtatctta ggaggttggt tgattgtaat
    10441 ctctatcttt gtcatgtacc tacttcaaaa gagagcttag gattgattcc taagtttttc
    10501 ttttgatact caatgaaaat caaagagcat agttgattga gtttggaata gtacgctgta
    10561 gctgctaaaa tatttctaga aattaatttg actttcctaa tagagttgtt catatcttat
    10621 ttcaatctac tatagaaagc tagccgcagg ttgctcaaaa tagtgttttg aggttgcaga
    10681 tggaaactga cgtggtttga agagattttc aagagtataa gatttttata cccatacaat
    10741 atttgtttta ggtccttgtt tacagactaa tttcttgata aaatagaggt tatgacgaga
    10801 tataaagcaa ctatttccta tgatggttat gcctttgctg gctttcagcg ccagcctcat
    10861 gcgcgtagcg ttcaggaaga aattgaaaaa accttgacca gattaaataa agggcaaacc
    10921 attactgttc acggtgctgg taggacagat agtggggttc atgccctggg acaggtcatt
    10981 cattttgacc tgccttatca gatggatgag gagaaactcc gttttgcctt ggatacccag
    11041 tctcctgaag atattgatgt gatttcgatt gagcttgtgg cagctgattt tcattgccgt
    11101 tatgccaagc atagcaagac ctatgagttt attgtggata gaggacgtcc caaaaatccg
    11161 atgcgccgtc actatgccac ccactttccc tacccactcg atgtggaacg aatgcagatt
    11221 gcaatcaaaa agctagaggg aacccatgat tttaccggtt ttacagcctc tgggactagt
    11281 gtagaggata aggttcgcac catcacagaa gctagtttaa tagtcgatga gacaggacaa
    11341 tttttgacct ttaccttttc cggaaatggt ttcttgtata aacagattcg caatatggtg
    11401 gggactcttc tcaaaatcgg taacaaccgc atgccagtag agcagattga tctcatcttg
    11461 gagaagaagg acaggcaact tgcaggtccc actgcagcac caaatggttt gtatttaaag
    11521 gagattcgtt atgaagaata atcgtatttt agcactttct ggaaatgata tttttagtgg
    11581 tggtggactg tcagctgatt tggctaccta taccttgaac ggcttgcatg ggtttgtagc
    11641 agtgacttgt ttgacagcct tgacagaaaa aggatttgaa gtctttccaa ctgatgatac
    11701 catttttcaa catgaattag atagcttgcg tgatgtggaa tttgggggaa ttaagattgg
    11761 tcttctccct actgtcagtg tggctgagaa ggccttggac tttatcaaac aacgcccagg
    11821 agtacctgtg gtgttggatc ctgtcttggt ctgcaaggaa acgcatgatg tagctgtcag
    11881 tgagctctgc caagagttga ttcgcttttt cccttatgtc agtgtgatta cgcctaatct
    11941 cccagaagca gaattattat ccggtcagga aattaaaacc ttggaagaca tgaaaactgc
    12001 agcgcagaaa ttgcatgatt taggagcgcc agcagtcatt atcaagggag gcaatcgtct
    12061 tagtcaggac aaggctgtgg atgtctttta tgatggacag acctttacta tcctagaaaa
    12121 tccagttatc caaggccaaa atgttggtgc aggttgtacc tttgcctcta gcattgccag
    12181 tcacttgatt aaaggtgata aacttttgcc agcagtagaa agctctaagg ctttcgttta
    12241 tcgtgctatt gcacaagcag atcagtatgg agtaagacaa tatgaagcaa acaaaaacaa
    12301 ctaaaatcgc ccttgtatcc ctattaaccg ccctttctgt ggttctaggt tatttcttaa
    12361 aaatcccaac acctacagga attctaactc ttttagatgc tggtgtcttc tttgcggcct
    12421 tttactttgg tagtcgtgaa ggagcggtag tcggaggact agcaagtttc ttgattgacc
    12481 tcttatcagg ctaccctcag tggatgttct ttagcttggt caaccatggc ttgcagggat
    12541 ttttcgcagg atttaaagga aaaagtcagt ggttaggcct tattttagca actattgcca
    12601 tggtaggagg ctacgccttg ggttctactt tgatgaatga ctgggcagca gccctcccag
    12661 aaattctacc aaattttatg caaaatatgg tagggatgat tgtaggattt attcttagtc
    12721 aaagtatcaa gaagattaag taatactctt cgaaaatctc ttcaaaccac gtcagcttcc
    12781 atctgcaacc tcaaaacact gttttgagca gcctgaggct agctttctag tttgcacttt
    12841 gattttcatt gagtataaag aggttgagta aaaagtattt caaataagaa aaacgcatag
    12901 tataggatgt tgaaatgatg aactgccccc caaaagttag acagaaaaaa tctaactttt
    12961 ggggtgtttt attatgaaac taacttatga tgataaagtt cagatctatg aacttagaaa
    13021 acaaggatat agcttagaga agctttcaaa taaatttggg ataaacaatt ctaatcttag
    13081 gtacatgatt aaattgattg atcgttacgg aatagagttc gtcaaaaaag gaaaaaatcg
    13141 ttactattct cctgatttaa aacaagaaat gattcataaa gtctgacatg aaggctggac
    13201 taaagataga gtttctcttg aatacggtct cccaagtcgt acgatacttc ttaactggct
    13261 agcacaatac aggaaaaacg ggtatactat tgttgagaaa acaagaggga gagtacctaa
    13321 aatgggacgt aagccaaaaa agagacctga agagaggaca gaattagaac gtcttcaagc
    13381 agaaaatgag tacctgagag cggagaatgc catcctaaaa aagttaagag aactccgatt
    13441 gaaggaggaa aaagagaaag acagaaattg tttaagaatt aatgactgag ttttcgttag
    13501 atcttcttct aaaagccatt aaactagctc gttcgaccta ctactatcac ttgaaacagc
    13561 tagacaaaac agataaggac caagagctta aagctgaaat tcaatccatt tttatcgaac
    13621 acaagggaaa ttatgcttat cgtcgaattc atttagaact aagaaatcgt ggttatctgg
    13681 taaatcataa aagagttcaa ggcttgatga aagtactcaa tttacaagct aaaatgcgac
    13741 agaaacgaaa atattcttct cataaaggag acgttggtaa gaaagcagag aatctcattc
    13801 aaggccaatt tgaaggctct aaaacaatgg aacagtgcta cacagatgtg actgaatttg
    13861 ccattccagc aagtactcaa aagctttact tatcaccagt tttagatggc tttaatagcg
    13921 aaattatcgc ctataatctt tcaacttcac ccaacttaga acaagtacaa acaatgttgg
    13981 aacaggcatt cacagagaag cactacgaga atacgattct ccatagtgac caaggctggc
    14041 aatatcaaca cgattcttat catcggttcc tagagagtaa gggaattcaa gcatctatgt
    14101 cacgcaaggg aaacagccaa gacaacggta tgatggaatc tttctttggc attttaaaat
    14161 ccgaaatgtt ttatggctat gagaaaacat ttaaatcact taaccaattg gaacaagcta
    14221 ttgtagacta tattgattac tacaacaata aacgaattaa ggtaaaacta aaaggactta
    14281 gtcctgtgca atacagaact aaatccttcg gataaattat ttgtctaact gtttgggggc
    14341 agtacatttt aacacttgat actatgcgtt ttattgtggg aagattttcc tcattttcta
    14401 gtgaaattga actttttcta acatcttttg atagatgact tcttaatcaa ttatcatttc
    14461 cattgttgtt tcttggggtt tcatcccttg tctttgataa aagcggagag caccctcgtt
    14521 atcattccag acacttaggg ttagattatt gcagccaatt tctttagcat aatagcagaa
    14581 aaatgacaat aaaatagccc ctagatattt tgaaaggaaa gcataggggc tatatagttt
    14641 aatcaaaata aagcaaatct ttgctggtgc ttgtaaagag gtcgaagcca tccttggtaa
    14701 caacaccgca gtcttcaata cgaacaccga ctttaccagg gatatagata cctggttcaa
    14761 cagagaagca catgccttct tcgatgacca tgtcgtttcc ttccatgata gatgggaatt
    14821 catggacatc cataccgata ccatgcccga gacggtggtt gaagtactca ccataaccag
    14881 ctttttcgat gacctcacgg gcagcgcggt ccacttcatg agcagtcaca cctggcttga
    14941 taaagtcaag agcagcttgt tgggcttcaa gagtcaagtt gtaaatatct ttcttgaatt
    15001 ggtctggttt gccgacagcg actgtacgag tcatatctga cgcatagcca ttgaccagaa
    15061 cacccaggtc aaagaggaga agagcatcat tttcaacctt attagctgct ggaatgccgt
    15121 gtggattcgc agcattatca ccagtcaaga ccatggtatc aaagctcatt tcataacctt
    15181 cacgtttcat ggcaaagtcg atttgtgcga tgatatctgt ctcagtctta tcaagagaaa
    15241 tattgtcaaa accaacatga acagccttgt cagcataaag acctgcaacc atcatttttt
    15301 gcacttcatc agctgatttg atgaggcgca tgcgttggat acgaggagtg aggttgtcaa
    15361 actcagcagt ctcaaaaact gttttcaaac catagtattt ggtcaagatg agattgtcaa
    15421 actcaacagc gacacgtttg aagtcaagtt gtggaagagc atgtttgatt ttttgccatg
    15481 gattttcaga atcgacatag cccactactg ggaaggaaac ggtgctactt gcacgttcta
    15541 cttcaagagc tgggacaaag aggagaggtt cctgatccgc taggacaaag aggaacattt
    15601 ggcgttcatg gggatcactg taaaaaccag tgaggtaatt gattgtgacg gggtcagata
    15661 cgacagcgac gtctagtttt tctgattcaa gatatattag gatttgttgt aatttagaca
    15721 tatgctacct tctttctacc cctctatttt ggcaaaaaat gagagaaaat gcaagggaga
    15781 agggtaaaag aaaagacaaa aaactccgac aagataacgg agttctttga tatcattttc
    15841 ctttgtttaa gaaaagtcag ccttgctttt gacgtcactg tactcttcag cgatttcttg
    15901 gctgagaatg tcctcatagg cagggagttg gatgtcctga ccatatttct tcttgagggc
    15961 agtagtaact aggcgataag ccagattggc attacgagag aggataggcc cgtggaagta
    16021 ggaaccaaag acattcttat aatgaacccc ttcaccgacc ttttcttcgt tgtttccatt
    16081 tccatagaca acctgtccca gcggtttttg gtcatcagag aggaaggtac gaccttggtg
    16141 attttcaaat ccatagtagg tttcatcgaa atcttcattg tgaatcttga tgtcaccgat
    16201 aaaacggtta ttggtctggt tgagcgtgta gtgtcccatg acccctagcc cttcgatacg
    16261 ttttcctgaa gcttcaacat aatattgacc caatagttgg aaaccaccgc agatagccag
    16321 aactacaccg tcgttttgga tgtagttgtc aatgctctct tttttagcag gtaggtcgtc
    16381 tgcaatgata ctttgttcaa agtcttgacc accaccgaaa aaggctatgt cgtagtgatt
    16441 ttcatcaaag tcatcatgga gagaaacgat gtcaacggtc acatgggctc ccagtttttc
    16501 agccacatac ttgagcatga ggatgtttcc attgtccccg taggtattca tgagatttcc
    16561 gtagaggtgg gcaatgttga gctgataggg gtaattgcca tcttttgagg aaagtgaagt
    16621 ataaaccatt agttcatctc ctttctaaca atctgacgac tagccagcag ttcacgaaat
    16681 tccagcatgg cagtataagt tgccagaata taggcatgct tgcagtcttg attctcaatg
    16741 gtcttgagaa cttgctccag attactcgtt tcagtgattt tctcagctgg atagccagtc
    16801 actcggaggc gacgagcgat ttcagaatga cgaacaccgc cagcgttgat ttcaggaatg
    16861 tccatgtcag tgatttgctc aaagtctgca tcccagatcc agctagtgtc aattccatct
    16921 gcatagttgg cattaaggag gacagatagg ctaaatggat aaggtgctag tttgatcatt
    16981 tcgatagctt gggttgcacc gactggattt ttaatcaaga caagggtaca ttccttgtca
    17041 ccgatatgaa aggtttcttg gcgtccaaag acagcacggc tcttgtcaaa tccctgtttg
    17101 atgagttgcg aatcggcacc taggaaacgg gcgatggcca cagcagctag ggcgttatag
    17161 atattataga gcccgccgat ttggataccg tattcttggc cgtctatgac aaagcgagag
    17221 cgattgttgg tcaactcaac cagttttgtc aaacgatagt cgagatcagg acgtttgcat
    17281 ccacaacctt cacagatata ggcacccaag tttgcatagg tattatgctc atatttgagg
    17341 atgccttggc agtcaggaca gagaatccct tcggtattgt agtgagccag ttgggctggt
    17401 cctttttcca agtcaaaacc aaaatactct atagggtttg gaatagttgg cttgtagaaa
    17461 agtggactgt ctccgttaag gagaacagta gcagttggaa ctttccgaat ggcttccaat
    17521 atcatgttat aggtagtata gatttcaccg aaacggtcca tctggtcacg gaagatatta
    17581 gtaatgacaa aaagactagg ctggatatag tcacagatac gagatagact ggcttcgtca
    17641 atttcgagga cggcaatatt tttcccagtt tttgaagatt tggctgttag gaaggttgtt
    17701 gcaatccctg taatcatgtt ggcaccgctt gggttggtta gaacttgacc ataaacctct
    17761 tttaaaatgc cgacagtgag ggcagttgtc agggtttttc catttgttcc agtgacaacg
    17821 acaatctcgt agttcttagc taggttttgt aaaatatctt tatcaaattg aagggcgact
    17881 ttacctggga gcgtacttcc acggccaaga cggcttaaaa tgaagtggga agaacgccca
    17941 gcaagaaggc ccaaagtagt ttttaagttc atgtttctat tatatcataa aagaggagaa
    18001 agacagattt gagattccgc agaagtaaaa acagcccaaa gagggctgtt cgatacgatt
    18061 aaatctcaac ttaaatcgca aacaagtcat tcaagttctc agccaaggtt gggtgagtga
    18121 agatttgttt tgtgaagtaa gtgtaaggaa tcttgttgtc catagcaaca gtgatgatgt
    18181 tgatgatttc ttgagaacct tctgagaaga tgcttgctcc aagaatttct tttgtttcag
    18241 tattgacaac agctttgaag gcaccgcgaa ggtctccatt tacgtgacca cgaggcattg
    18301 ctgcaacggg gatttcctta acagcgtatg gaagtttcaa atcagctgct tggctttcag
    18361 tcaaaccaac ttgtgaaagt gcaggtgtga tgaacatagt atttggcaca ttgagacggt
    18421 cttcaagtgt gtagctgcca tctccagcaa ggtagctgta aacaacacgg aagtcatcaa
    18481 gtgaaatgta agtaaattga aggccaccgt tgacatctcc aactgcaaag acaccaggaa
    18541 cgtttgtttg acagtgtttg tctactttaa tagcaccacg ttcagttagt tcaatatctg
    18601 tattttcaag ttgaagtggt tctacatttg gtttgcgtcc agttgcgtag agaagggcgt
    18661 cgaaacggta agtttcgtct tcagttacga caagcacttg gtcaccatcg tttttgattt
    18721 cagtagtatg gatattttga agcaattcaa tgccatcttc ttccatgtat tgtttagcaa
    18781 gagctgcgat ggaaggttct gcacgaggta ggaatgtatc caaggcatct aggactgtga
    18841 ccttgcttcc aagtttgttg taaaggccgg caaattcaag accgatattt ccgccaccaa
    18901 ggattccaag tttttcaggt aatttgtcca agctttggat acctgttgag tcaaagatgt
    18961 ttttgcttgt agcaagtcca gggattggca agacgtttga aacagcacca gtgttgatga
    19021 cgattgtttc agcagtcagt tctttctttt catcaccagc ttggatttcg atgactttat
    19081 ttgaaaggaa gtgagcttcc gcatcaaaga tatctacgcc tgtaccagca acagtcgcat
    19141 agtttttacc gttgaggcga ccagtgatcg tgtttttagt agcaatgact tcttcaaaag
    19201 acaagtcctt ttcagcagca actagcaagg ttttagttgg gatacaacca atgttgatac
    19261 aagttccacc gtacatagcc ttgctgcgtt caacgagggc aacttttttg ccagctgaag
    19321 ccaatttacc tgctagtgtt ttaccagctt taccaaatcc aataacaatt aaatcgtatg
    19381 ttaacattta tcttcctcct attcgaattt cattctagca caagaaaaaa acttttgcac
    19441 aattctgcta cggaaaagac agaaaaagat aaaaacgctt tccagacaaa aaactagtaa
    19501 ttttttgaca agcttgataa actaaaatcc tatctatttt tatataagat agaataaatg
    19561 ttcgaaaata ggaggtttta tgaaatcgaa tcgttatatt attgcctttg ctggggtcat
    19621 tttacactta atgctgggtt cgacttatgc ttggagtgtt tatcgtaacc ctattattga
    19681 aaaaacggga tgggatcagg cttctgttgc cttcgccttt agtctagcaa tcttttgttt
    19741 gggtttatcg gctgcattta tggggcgttt ggtagaaaaa tttggtccga aagtcatggg
    19801 gagtctatct gcttttctat acgcaggtgg aaatatctta acaggatttg caatagaccg
    19861 tcaggaactg tggttgttgt atctagctta tggcatttta ggtgggcttg gtttgggagc
    19921 aggctatatt acccctgtgt caacgattat aaaatggttt cctgataaac gtggtctcgc
    19981 aacaggttta gcgattatgg ggtttggttt tgcttcttta ttgactagtc ccatagcgca
    20041 acaccttatc gcaggggtag ggattgtaga aactttttat attttaggag caagttactt
    20101 tattatcatg ctcctagctt cacaattcat taagcgtcca aatgagcaag agcttgcaat
    20161 tttatcttct tcagggaaag aaaaaacagc ctctttgacg caaggaatgg ctgcaaatca
    20221 ggctctaaaa agcaatcggt tttatatgct ttggattatt ttctttatca acatagcttg
    20281 tggtttaggc ttaatttcag cggcatcgcc aatggcacag gagatggctg gcttgtctac
    20341 aagtcatgca gcagtaatgg tgggtgtttt ggggattttc aatggatttg gtcgcttgct
    20401 ctgggcgagt ttgtctgact atatcggtcg ccctctaacc tttagtatat tactgcttgt
    20461 caatcttttc ttttctctct cactttggct ctttacagat tccgttttat ttgtagttgc
    20521 tatgtctatt ttgatgactt gctatggagc tggtttttct ttgattccag cttatctcag
    20581 tgatattttt ggaaccaagg aattggccgc tctgcatggt tatattttaa cagcttgggc
    20641 aatggctggt ttagcgggac ctattttatt agcagagact tataaaatgg ctcattcgta
    20701 cacacaaacc ttgttcgttt ttctcatttt atacagtatc gccttggctt tgtcttatta
    20761 tctaggtcgt tcaatcaaaa aagaaagtca aaaaccgctt acatgatttt ctgtagaaat
    20821 ggggctatct tttgctctgg tcttgtgtta tactagatag gttgcaaaga aaacagtact
    20881 tttcttttgt ggaaaagaag caacacgatt ttatatctag ttatatgaaa atacgtcata
    20941 aaaagaaaag tataaactaa gccctatagg gtggcttcgc accaccttta gaaagaagaa
    21001 taacgtgaaa tttaatgaat taaacttgtc tgctgatttg ctagcagaaa ttgaaaaagc
    21061 tggttttgta gaagctagtc ctatccaaga acaaactatt cctttggccc ttgaaggcaa
    21121 ggatgttatc ggtcaagctc agactggtac aggaaaaact gcagcctttg gcttgcctac
    21181 ccttgaaaaa atccgtacag aagaagcgac tatccaagct ttggtcatcg ctccaactcg
    21241 tgaactagct gtccaaagtc aagaagaact cttccgcttt ggtcgtagta agggagtcaa
    21301 agtccgttca gtatatggcg gatcaagcat tgaaaaacaa attaaggctc ttaaatctgg
    21361 tgcccatatc gtggtgggaa ctccaggtcg cctcttggac ttgattaaac gcaaggcctt
    21421 gaaattacaa gacattgaaa cccttatcct tgacgaagcg gatgaaatgc ttaacatggg
    21481 cttccttgaa gacatcgaag ccattatttc ccgtgtacct gagaaccgtc aaactttgct
    21541 tttctcagca actatgccag atgccatcaa acgtatcggt gttcagttta tgaaagcccc
    21601 tgaacatgtc aagattgcgg ctaaggaatt gacaacagaa ttggttgacc agtactatat
    21661 ccgtgttaag gaacaagaaa aatttgacac catgactcgt ctcatggatg tggcacaacc
    21721 agaactcgct attgtatttg gtcgtaccaa acgccgtgtg gatgaattga ctcgtggttt
    21781 gaaaattcgt ggcttccgtg cagaaggaat tcatggcgac ctagaccaaa acaaacgtct
    21841 tcgtgtcctt cgtgacttta aaaatggcaa tcttgatgtt ttggttgcga cagacgttgc
    21901 agcgcgtggt ttggatattt caggtgtgac ccatgtctac aactacgata ttccacaaga
    21961 tcctgagagt tatgttcacc gtatcggtcg tacaggtcgt gctggtaagt caggtcaatc
    22021 tattactttt gttgctccaa acgaaatggg ttaccttcaa atcattgaaa acttgactaa
    22081 gaaacgcatg aaaggtctca aacctgcaag tgtagaagaa tccttccaat caaaaaaaca
    22141 ggtagctctc aagaaaatcg aacgtgattt tgcagatgaa accattcgtg ccaactttga
    22201 gaaatttggt aaggatgctc gcaaattggc tgctgagttt actccagaag aattggcaat
    22261 gtatatcttg agtctgacag tccaagaccc agatagcctt ccagaagtgg agattgcacg
    22321 tgaaaaacca ctaccgttta aaccatcagg taatggtttc ggtggtaaag ctaagggagg
    22381 tcgtggaggc cgtcgtgggg atgaccgtcg agagcgtgat cgccgtggca atggtcgccg
    22441 tgatgagttc aaaaaaggaa gtcgtggcaa cgatcgtttt gataaggaaa aacgttaccg
    22501 taaggataat aaaaaaccac gcaatacttt aaacgaaaag caaacaggct ttgttattcg
    22561 taacaaaggt gataaataag aaaaagcggt tcaaaatgaa tcgctttttt atataaggag
    22621 accgaatgtg aaaaagacaa ataaaattat tatattatct tttataatat tatgatacaa
    22681 aaaaataggc aacttgtcaa tagaaaagga acaatttaat taaaaatatt ctggttttta
    22741 attaaattgt aagtcaatgc aagtcaataa ggaattttca gataattatt gaaaaagaga
    22801 cgtttttatg ttataatgat agcgattaaa ttcgaggtga aaaatggcac atttattaga
    22861 aaaaactaga aaaattacat caattttgaa acgctcagag gagcagttgc aggatgagct
    22921 tccttacaac gctattacgc gtcagttagc ggatattatt cattgcaatg cctgcattat
    22981 caatagtaag ggacgtctgc ttggctattt tatgcgttat aaaacaaata cagatcgcgt
    23041 agagcaattc ttccaaacta agattttccc agatgactac gttcaagggg ctaatatgat
    23101 ttacgaaaca gaagcaaact tacctgttga gcatgatatg agtattttcc ctgttgagag
    23161 tagagatgat tttccagatg gcttgacgac tattgcaccg attcatgtat cggggattcg
    23221 ccttggttct ttgattattt ggcgtaatga taaaaaattc gaagatgagg acttggttct
    23281 tgttgagatt gccagtaccg ttgttgggat tcagcttctt aacttccaac gtgaagaaga
    23341 tgagaaaaat attcgtcgtc gtactgctgt caccatggcg gtcaataccc tttcttactc
    23401 cgaactccgt gctgtttcag caattttagg ggaattaaat ggaaatgaag ggaagttgac
    23461 tgcgtcagtg attgcagatc gtatcggaat cactcgctct gtgattgtca atgctcttcg
    23521 taaacttgag tctgcgggga ttattgaaag tcgctcactt ggaatgaagg gaacctatct
    23581 taaggtcttg atttcagata tttttgaaga agtgaagaaa agagattact aatgacaaag
    23641 gctttaattt cgattgatta tacagaagat tttgttgctg atagtgggaa actaacagca
    23701 ggtgctccag ctcaggcgat ttcggatgcc atcagcaagg taactcgatt agcttttgaa
    23761 cgaggagatt atatcttctt tactattgat gctcatgaag aaaacgattg tttccatccg
    23821 gaaagtaagt tatttcctcc tcataatctg attgggacga gtggacggaa tttatatgga
    23881 gatttgggga tcttttatca agagcatggt tcagacagtc gtgtcttttg gatggataaa
    23941 cgccattact cagctttttc agggactgac ctagatattc gtttgagaga gcgtagagtg
    24001 tctaccgtta tcttaacagg tgtcttgacg gatatctgtg tcctacatac agctatagat
    24061 gcctataatc taggatatga catcgagatt gttaaaccag ctgttgcttc catctggcct
    24121 gaaaatcatc aatttgccct aggtcatttc aaaaatacac tcggagctaa gttagtagat
    24181 gaaaatctaa atgaactttc tgagtaacct ggttggtgaa aatgaaaaaa tttgaaaaaa
    24241 agtgttgaca agcatcccaa aagttgatat actagtaaag taatcgacgc ggggatggcg
    24301 gaattggcag acgcgcagga ctaaggatcc tgtgaccgct ttaggtcgtg agggttcaag
    24361 tccctctctc cgcataggaa aagagctagc taaagctagc tcttttgtat ttctctaaaa
    24421 aattagaatc cagtcaaatg tagtggagaa tcagcgaaaa tatgggaaaa ctgatccttg
    24481 tttctgcttt tgtctataga agaataataa agattatctt cttcaaattc tccgatattc
    24541 tctaaagttt tgtgcaagtt gcacagaact tttttatttt tttggtcatc ttgccataga
    24601 aatataaagc gttttcatct ataatataat tatcaaaaga caaaaggagt tcacctcatg
    24661 gtagaattga atcttaaaaa tatttacaaa aaatatccaa acagcgaaca ctattcagtt
    24721 gaagatttca acttgaacat caaagataaa gaatttatcg ttttcgtagg accttcagga
    24781 tgtggtaaat caactacact ccgtatgatt gctggtcttg aagacattac agaaggtact
    24841 gcatctatcg atggcgtggt tgtcaacgac gtagctccaa aagaccgtga tatcgccatg
    24901 gtattccaaa actacgctct ttacccacac atgactgttt atgacaacat ggctttcggt
    24961 ttgaaattgc gtaaatacag caaagaagac attaacaaac gtgttcaaga agcagctgaa
    25021 atacttggat tgaaagaatt cttggaacgt aaaccagctg acctttcagg tggtcaacgt
    25081 caacgtgttg ccatggggcg tgcgattgtc cgtgatgcga aagtattctt gatggacgaa
    25141 cctttgtcaa acttggatgc caaacttcgt gtatcaatgc gtgctgaaat cgctaaaatt
    25201 caccgtcgta tcggagctac aactatctat gtaactcacg accaaacaga agcgatgaca
    25261 cttgcagacc gtatcgttat tatgtcagct actaagaacc ctgctggtac aggtactatc
    25321 ggacgtgtag aacaaatcgg tactcctcaa gaagtttaca aaaatccagt taacaaattc
    25381 gttgcaggat tcatcggaag cccagctatg aacttcatca acgtgaaatt ggttggtagc
    25441 gaaattgttt ctgacggttt ccgtttgaaa gtgccagaag gagcattgaa agttcttcgt
    25501 gaaaaaggct acgaaggaaa agaattgatc tttggtatcc gtccagaaga cgtgaatgca
    25561 gaacctgctt tccttgaaac attcccagac tgtgttgtaa aagcgactat ctctgtatca
    25621 gaactgcttg gttcagaatc tcacctttac tgccaagttg gtaaagacga gtttgttgca
    25681 aaagttgatg ctcgtgacta cttgcaaaca ggtgcaacag ttgagcttgg atttgacttg
    25741 aacaaagcac acttcttcga tgtagaaact gaaaaaacaa tctactaaaa taaataaaat
    25801 tcaaagcact acaagaaaag atatctcttt atcaattgta gtggagagat atcagttaat
    25861 ctagggagag aaacaaaatg cttctctcct ttttgctagg gaagtcatat tatgcatcta
    25921 tattgtgatg ctctttaata ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg
    25981 ccgtacgtat gattactgac ttcgtcagtt ttatctgcaa cctcaaagct gtactttgag
    26041 cagcttacgg ctagttttct agttttctct ttgatttcca ttgagtatta tttgtgggta
    26101 ccatctacaa gtgaagctat atgcgtaaac tacgtgagca attgaattcg aactagagag
    26161 gtaataataa atttatgcta tagttatggt gacttgtatg cttttgattc tagtttatca
    26221 aataatagat tagaattgtc agataatatc attttgtgtt ataatgaaga aaaaacagag
    26281 gtgttcaaat gtcagaagca ggtcataagt ttttagcaaa attggggaaa aaacgcttac
    26341 gtccaggtgg aaagcgtgcc acagattggt taattgcaga aggaggattt tcaaaagaaa
    26401 agagaatact agaggttgcg tgtaataggg gaactacagc aattgagttg gcacagcgtt
    26461 ttggttgcaa gataactgct attgatatgg atgctcaagc tttagaagtg gctaaaaaat
    26521 ctgctggaac ggcaggtgtt gctcatttaa tcagttttga aagagcaaat gcaatgaaac
    26581 ttccttatca agatgctagt tttgatattg ttataaatga agctatgctg actatgcaag
    26641 ccgatcaagc taagaaaaaa tgtgtaatgg aatatctaag ggtattaaaa cctggaggtc
    26701 ttctcttgac acatgatgtg cttcttaagg aagctaaaga gtctatcaga caggaattat
    26761 cacaagcaat tcatgtaaat gtaggtcctt taactcaaga tggttgggaa caggtgatga
    26821 tagaatcagg ttattgtgat gtgaaagcat tgactggtga aatgacatta atgaaattat
    26881 cgggtatgat ttatgacgaa ggtttgctag gaactttgaa aatttgtgta aatgcttgta
    26941 aaaaggagaa tagaaagcag tttttaacta tgtataaaat gtttgctaag aataaacaga
    27001 aattgggctt tattgcgatg gctagttata aatcgtcaaa acgttagata attattgaag
    27061 ttaacttttc cttttttctt tcttaaaaaa tatgctataa tagagagtaa aaaactttga
    27121 aagaaagaaa aagatgaatt taaaagatta cattgcaaca attgaaaatt atccaaagga
    27181 aggcattacc ttccgtgata ttagtccttt gatggctgat ggaaatgctt atagctacgc
    27241 tgttcgtgaa atcgttcagt atgctactga caagaaagtc gacatgatcg tgggacctga
    27301 agctcgtgga tttatcgtgg gttgtccagt tgcctttgag ttgggaattg gttttgcgcc
    27361 tgttcgtaag ccaggtaaat tgccacgcga agttatttct gctgactatg aaaaagagta
    27421 cggtgtcgat accttgacta tgcacgcgga tgccattaag ccaggtcaac gtgttcttat
    27481 tgtagatgac cttttggcga caggtggaac tgttaaggca actatcgaga tgattgaaaa
    27541 acttggtggt gttatggcag gttgtgcctt ccttgttgaa ttggatgaat tgaacggccg
    27601 tgaaaaaatt ggtgactacg actacaaagt tcttatgcat tattaatgaa aacagtccct
    27661 agggctgttt tctctacact aggatataaa aatagactat aactagttag agaaaaacta
    27721 taattgaaaa ctatatcttc ttacagtata ataaaaggac taagtgtttg agatttgtct
    27781 tcaaacatat gcaattattc ctgaaagagt acagttagga gagggttatg ccgattcgaa
    27841 ttgataaaaa attgccagct gttgagattt tacggacaga gaatatcttt gtcatggatg
    27901 atcaacgtgc tgcccaccaa gatatccgtc ctttgaagat tttaatttta aatctcatgc
    27961 cacagaaaat ggtcacagag acccagttgt tgcgccactt ggctaataca cccctacaac
    28021 tggatattga ttttctctat atggagagcc accgttctaa aacaactcgt tcagagcaca
    28081 tggagacctt ctataaaact tttcctgaag tcaaggatga gtattttgat gggatgatca
    28141 tcacgggtgc tccagttgag catttaccat ttgaggaagt ggactattgg gaggaattta
    28201 gacagatgct tgagtggtct aagactcatg tctattcgac ccttcatatc tgttgggggg
    28261 ctcaggctgg gctttatctg cgctatggtg tagaaaaata ccagatggac agtaagctat
    28321 caggtattta tcctcaggac accctaaaag agggtcacct tctatttaga ggctttgatg
    28381 atagctatgt atcccctcat tcacggcaca cggagatttc taaggaagag gtcttaaaca
    28441 agaccaatct cgagatttta tcagaaggac ctcaggttgg ggtttctatt ttggccagtc
    28501 gtgatttacg agaaatttat agttttggtc atttggagta tgaccgtgat accttggcaa
    28561 aagagtattt tcgagatcgt gatgcaggtt tcgacccaca tattccagaa aattacttta
    28621 aagatgatga tgttaatcag gtaccttgtc tttgttggtc ttcatctgca gccctctttt
    28681 tcagtaattg gataaaccat gcggtctatc aggagacgcc ttttgattgg agaaagatag
    28741 aagatgatgc atctgcatat gggtatttat aagaggaatt atgacatatt tagacgcttt
    28801 taaatcaggt atcttggttt taccgagtgc cctgctcttg cattttaagg aactctttcc
    28861 ttctagcgac gattttctgg tttggcaatt tttctatttg caaaatacga caggcttaga
    28921 agaaatgtcg ccaagccaga ttgctgaaag gattggcaag gaaatttcgg atgtcaacca
    28981 gtccatttct aatctgacgg aaaggggact gctccagtat cgtactatcg aattaaatgg
    29041 cgaaattgaa ttgctctttg atgctagttt ggccttggaa cgtttggatg acctgtttgg
    29101 agcagttcat tcaagttcag accagctgac acctcaaaac cagctcaagg atttggtgga
    29161 aaccttccag caggagttgg gacgattgtt gacgcctttt gagattgagg atttgaccaa
    29221 gacactaaag gaagatggaa ccagtgctga cttgattaag gaggctcttc gtgaagctgt
    29281 tttgaatgga aaaccaaact ggaagtacat tcaggcgatt ttgagaaact ggcgccatga
    29341 aggaatcaag agtgtggctc aaattgaggc caagagagca gaaagagaag caagcaatcc
    29401 tcagttgaca caggtatctg cagatttcag aaatgccatg gatctctgga aggattaatc
    29461 catgcaagca ggcttgaaat ccgagtaaga tttgcaagct gtgtataatt gtgatagaat
    29521 aaaatagaaa ataaattgaa aaaagaggta tgtgaaatgt cacgtaaacc atttatcgct
    29581 ggtaactgga aaatgaacaa aaatccagaa gaagctaaag cattcgttga agcagttgca
    29641 tcaaaacttc cttcatcaga tcttgttgaa gcaggtatcg ctgctccagc tcttgatttg
    29701 acaactgttc ttgctgttgc aaaaggctca aaccttaaag ttgctgctca aaactgctac
    29761 tttgaaaatg caggtgcttt cactggtgaa actagcccac aagttttgaa agaaatcggt
    29821 actgactacg ttgttatcgg tcactcagaa cgccgtgact acttccatga aactgatgaa
    29881 gatatcaaca aaaaagcaaa agcaatcttt gcgaacggta tgcttccaat catctgttgt
    29941 ggtgaatcac ttgaaactta cgaagctggt aaagctgctg aattcgtagg tgctcaagta
    30001 tctgctgcat tggctggatt gactgctgaa caagttgctg cctcagttat cgcttatgag
    30061 ccaatctggg ctatcggtac tggtaaatca gcttcacaag acgatgcaca aaaaatgtgt
    30121 aaagttgttc gtgacgttgt agctgctgac tttggtcaag aagtcgcaga caaagttcgt
    30181 gttcaatacg gtggttctgt taaacctgaa aatgttgctt catacatggc ttgcccagac
    30241 gttgacggtg cccttgtagg tggtgcgtca cttgaagctg aaagcttctt ggctttgctt
    30301 gactttgtaa aataatcagt aagtagcaaa agctaggtgg aacagcattc agatgtctgt
    30361 tacatttttt ataggagagg aaagattgaa aataaaaatt ggattagcaa gtatctgttt
    30421 actaggcttg gcaactagtc atgtcgctgc aaatgaaact gaagtagcaa aaacttcgca
    30481 ggatacaacg acagcttcaa gtagttcaga gcaaaatcag tcttctaata aaacgcaaac
    30541 gagcgcagaa gtacagacta atgctgctgc ccactgggat ggggattatt atgtaaagga
    30601 tgatggttct aaagctcaaa gtgaatggat ttttgacaac tactataagg cttggtttta
    30661 tattaattca gatggtcgtt actcgcagaa tgaatggcat ggaaattact acctgaaatc
    30721 aggtggatat atggcccaaa acgagtggat ctatgacagt aattacaaga gttggtttta
    30781 tctcaagtca gatggggttt atgctcatca agaatggcaa ttgattggaa ataagtggta
    30841 ctacttcaag aagtggggtt acatggctaa aagccaatgg caaggaagtt atttcttgaa
    30901 tggtcaagga gctatgatgc aaaatgaatg gctctatgat ccagcctatt ctgcttattt
    30961 ttatctaaaa tccgatggaa cttatgctaa ccaagagtgg caaaaagtgg gcggcaaatg
    31021 gtactatttc aagaagtggg gctatatggc tcggaatgag tggcaaggca actactattt
    31081 gactggaagt ggtgctatgg cgactgacga agtgattatg gatggtgctc gctatatctt
    31141 tgcggcctct ggtgagctca aagaaaagaa agatttgaat gtcggctggg ttcacagaga
    31201 tggtaaacgc tatttcttta ataatagaga agaacaagtg ggaaccgaac atgctaagaa
    31261 aatcattgat attagtgagc acaatggtcg tatcaatgat tggaaaaagg ttattgatga
    31321 gaacgaggtg gatggtgtca ttgttcgtct aggttatagc ggtaaagaag acaaggaatt
    31381 ggcgcataac attaaggagt taaaccgtct gggaattcct tatggtgtct atctctatac
    31441 ctatgctgaa aatgagaccg atgctgagaa tgacgctaaa cagaccattg aacttataaa
    31501 gaaatacaat atgaacctgt cttaccctat ctattatgat gttgagaact gggaatatgt
    31561 aaataagagc aagagagctc caagtgatac agatacttgg gttaaaatca tcaacaagta
    31621 catggacacg atgaagcagg cgggttatca aaatgtgtat gtctatagct atcgtagttt
    31681 attacagacg cgtttaaaac acccagatat tttaaaacat gtaaactggg tagcggccta
    31741 tacgaatgct ttagaatggg aaaaccctta ttattcagga gaaaaaggtt ggcaatatac
    31801 ctcttctgaa tacatgaaag gaatccaagg gcgcgtagat gtcagcgttt ggtattaagc
    31861 aatgatttga aagagggatg tgatagtagc accctctttt tctttgtttt atgatagttc
    31921 atcctcgagt aaattcaaga tcttgctcgg aaatgaagct tatatagtag attgaatata
    31981 gacaaatacc ttgtgattgg taaaacattt tagaaattca tttacctttc ctaatcgact
    32041 tggtttcatc ttatttcaat ctattatagt attggggaat ttcttcaaac cacatcagct
    32101 tggtcagttc tacctgcgac ctcaaaactt gtgctttggt caagctgggt ttagtttcct
    32161 agtttgctga tggatttcca ttgactataa gcatccaaac ctcttttttg tcttctaaag
    32221 aattcttaaa ttatcagtct attgcaactt ttctcatata agttctttgt cttgctattg
    32281 gttttcctta gtagtatact aaggtagtaa tcattaagaa gtggttacaa aaaataatga
    32341 atgaggtaaa gaaaatggta gaattgaaaa aagaagcagt aaaagacgta acatcattga
    32401 caaaagcagc gccagtagca ttggcaaaaa caaaggaagt cttgaaccaa gctgttgctg
    32461 atttgtatgt agctcacgtt gctttgcacc aagtgcactg gtatatgcat ggtcgtggtt
    32521 tccttgtatg gcatccaaaa atggatgagt acatggaagc tcttgacggt caattggatg
    32581 aaatcagcga acgcttgatt acactcggtg gaagcccatt ctctacattg acagagttcc
    32641 ttcaaaatag tgaaatcgaa gaagaagctg gtgaatatcg taatgttgaa gaaagcttgg
    32701 aacgtgttct agctatttat cgctacctca tcactctttt ccaaaaagcg ttggatgtga
    32761 ctgacgaaga aggcgatgat gttacaaacg atatttttgt tggtgctaag gctgaacttg
    32821 agaaaacagt ttggatgctt gccgcagaac ttggacaagc acctggtttg taagaaataa
    32881 tagcaatata tataaatctg taagaagttt cttacagatt tttttctatt ctgtaagcta
    32941 ttccaaacca gtcttttttt gagttttttg ataaaatagt actatcagtg aaaaggatgg
    33001 aagcatgact aagaaaattg tagctatttg ggcccaggat gaagagggtg tgattggtaa
    33061 ggacaatcgt ctgccttggt atttaccagc agaactgcaa cacttcaaag aaacaactct
    33121 gaatcatgct atcttgatgg ggcgcgtgac ctttgatggg atggggcgtc gactgcttcc
    33181 aaaacgggag accttgattt tgacacgtaa ttcagaagaa aagatagatg gggttactac
    33241 tttttatgat gttcagtctg tcttggactg gtatcatgct caagacaaga atctctatat
    33301 tcttggtggg aagcaagttt ttcaggcttt tgaaccctac cttgacgaag tgattgtgac
    33361 tcaaattcat gctcgggtgg agggagatac ctatttccct gaagagtttg acttgtccct
    33421 ttttgagaca gtttcaagca aatcctttac caaagatgag aaaaaccctt atgattttac
    33481 catccaatac cgcaagagaa aggaagtcta atggaacgta gtatatttgg ttttttcaca
    33541 gccatgctgt gtttggtctg cttacttgca ggagcacagg cttttcgtaa aaagcgttat
    33601 gggctttctg tcctgctctg gttaaatgcc tttaccaatt tggtcaatag tatccatgct
    33661 ttttacatga ccttatttta gatagaatga cagtatagaa tagaacggaa ggaaatcatg
    33721 cctacaacta ggaataatga tatgatggtt tattgctcat tttgtggcaa aagccaagaa
    33781 gaagtacaaa aaataatcgc agggaacaac gcctttatct gtaatgaatg tgtggagtta
    33841 gcccaggaaa tcattcgtga ggagttggct gaggaagttt tggcagactt gtctgaagtt
    33901 ccaaaaccaa tcgaacttct ccatatcttg aaccactatg taatcggtca agatcgtgcc
    33961 aaacgggcct tagcagtggc ggtttacaac cactacaaac gcatcaattt ccacgatacg
    34021 cgtgaagagt cagaagatgt ggatttgcag aagtcaaaca tcttgatgat tggcccaact
    34081 ggttcaggga aaactttcct tgctcagacc ttggctaaga gcttgaatgt accttttgct
    34141 attgcggatg cgacagctct gacggaggct ggttatgtgg gtgaggatgt ggaaaatatc
    34201 cttctcaaac tcttgcaggt tgctgacttt aacatcgaac gtgcagagcg tggcattatc
    34261 tatgtggatg aaattgacaa gattgccaag aagagtgaga atgtgtctat cacacgtgat
    34321 gtttctggtg aaggggtgca acaagccctt ctcaagatta tcgagggaac tgttgctagc
    34381 gtgccgcctc aaggtggacg caaacatcca caacaagaga tgattcaagt ggatacaaaa
    34441 aatatcctct tcatcgtggg tggtgctttt gatggtattg aagaaattgt caaacaacgt
    34501 ctgggtgaaa aagtcatcgg atttggtcaa aacaataagg cgattgacga aaacagctca
    34561 tacatgcaag aaatcatcgc tgaagacatt caaaaatttg gtattatccc tgagttgatt
    34621 ggacgcttgc ctgtttttgc ggctcttgag caattgaccg ttgatgactt ggttcgcatc
    34681 ttgaaagagc caagaaatgc cttggtgaaa caataccaaa ccttgctttc ttatgatgat
    34741 gttgagttga aatttgacga cgaagccctt caagagattg ctaataaagc aatcgaacgg
    34801 aagacagggg cgcgtggact tcgctccatt atcgaagaaa ccatgctaga tgttatgttt
    34861 gaggtgccga gtcaggaaaa tgtgaaattg gttcgcatca ctaaagaaac tgtcgatgga
    34921 acggataaac cgatcctaga aacagcctag aggtgactat ggaacttaat acacacaatg
    34981 ctgaaatctt gctcagtgca gctaataagt cccactatcc gcaggatgaa ctgccagaga
    35041 ttgccctagc agggcgttca aatgttggta aatccagctt tatcaacact atgttgaacc
    35101 gtaagaatct cgcccgtaca tcaggaaaac ctggtaaaac ccagctcctg aactttttta
    35161 acattgatga caagatgcgc tttgtggatg tgcctggtta tggctatgct cgtgtttcta
    35221 aaaaggaacg tgaaaagtgg gggtgcatga ttgaggagta cttaacgact cgggaaaatc
    35281 tccgtgcggt tgtcagtcta gttgaccttc gtcatgaccc gtcagcagat gatgtgcaga
    35341 tgtacgaatt tctcaagtat tatgagattc cagtcatcat tgtggcgacc aaggcggaca
    35401 agattcctcg tggtaaatgg aacaagcatg aatcagcaat caaaaagaaa ttaaactttg
    35461 acccgagtga cgatttcatc ctcttttcat ctgtcagcaa ggcagggatg gatgaggctt
    35521 gggatgcaat cttagaaaaa ttgtgaggaa aagaaaatgg caaaaacaat tcatacagat
    35581 aaggccccaa aggctatcgg accctatgtt caaggaaaaa tcgttggcaa ccttttgttt
    35641 gctagcggtc aagttcccct atcccctgaa actggggaaa ttgtaggaga gaatatccaa
    35701 gaacagacag agcaagtctt gaaaaacatc ggtgctattt tggcagaagc aggaacagac
    35761 tttgaccatg ttgtcaaaac aacttgcttc ttgagcgata tgaacgactt tgttcctttt
    35821 aatgaggttt accaaacggc cttcaaagag gaattcccag ctcgttcagc tgtggaggta
    35881 gctcgtcttc ctcgtgatgt aaaagtcgaa attgaagtca tcgcagagat tggataagct
    35941 agttgaagtt tggtgttgcc aaacttcttt tgatataagg agaaaaagat gacaaagaaa
    36001 caacttcact tggtgattgt gacagggatg agtggcgcag ggaaaactgt agccattcag
    36061 tccttcgagg atctaggtta tttcaccatt gataatatgc cgccagctct cttgcctaag
    36121 tttttgcagc tggttgaaat taaggaagat aatcctaagt tggctttggt agtggatatg
    36181 cgtagccgtt ctttcttttc agagattcaa gctgttttgg atgagttgga aaatcaagat
    36241 ggtttggatt tcaaaatcct ctttttggat gcggctgata aggaattggt cgctcgttac
    36301 aaggaaacca gacggagtca cccactagca gcagacggtc gtattttaga tggaatcaag
    36361 ttggaacgtg aactcttggc acctttgaaa aatatgagcc aaaatgtggt ggatacgact
    36421 gaactcactc cacgtgaact gcgcaaaacc cttgcagagc agttttcaga ccaagaacaa
    36481 gcccagtctt tccgtatcga agtcatgtct ttcggattta agtatggaat cccgattgat
    36541 gcggacttgg tctttgatgt ccgtttcttg ccaaatccct attatctacc agaactgaga
    36601 aaccaaacgg gtgtggatga acctgtttat gattatgtca tgaaccatcc tgagtcagaa
    36661 gacttttatc aacatttatt ggccttgatt gagccgattc tgccaagtta ccaaaaggaa
    36721 ggtaagtccg ttttgaccat tgctatggga tgtacgggtg gacaacaccg tagtgtggca
    36781 tttgctaaac gcttggcgca ggacttatcc aagaattggt ctgttaatga agggcatcgc
    36841 gacaaagacc gcagaaagga aacggtaaac cgttcatgag aaaaccaaag ataacggtga
    36901 ttggtggagg gactggaatt cccgtcattc taaaaagtct gcgggaaaaa gatgtggaaa
    36961 tcgcagctat cgtgacggtg gcagatgatg gtggttcttc aggtgaactc cgaaaaaata
    37021 tgcaacagtt gacaccgcca ggtgatcttc gtaatgtcct tgtggccatg tcggatatgc
    37081 ctaagtttta tgagaaggtc tttcagtatc ggttctctga ggatgccgga gcctttgctg
    37141 gccatccatt gggaaatctc atcattgctg gcttgtcaga aatgcagggt tcaacctata
    37201 atgccatgca gttattgagc aaatttttcc atacaacagg gaaaatttat ccttccagtg
    37261 accatccttt gacccttcat gcagtctttc aggatgggac agaagtggct ggagagagtc
    37321 atattgtaga ccatcgaggc ataattgaca atgtctatgt gaccaatgcc ctaaacgatg
    37381 atacgcctct ggccagccgt cgagtagtgc agaccatcct tgaaagtgac atgattgtcc
    37441 tagggccagg ttccctcttt acctctattt tgcccaatat cgtgattaag gaaattgggc
    37501 gggctctttt ggaaactaag gcagaaattg cctatgtctg caatatcatg acccaacgtg
    37561 gggagacgga acactttaca gatagcgacc acgtggaagt cttgcatcgt caccttggtc
    37621 gcccttttat cgacactgtc ttggtgaata ttgaaaaagt gcctcaggaa tacatgaatt
    37681 ccaaccgttt tgatgaatac ttagtgcaag tggaacacga ttttgtaggt ctttgtaagc
    37741 aagtttcgcg cgtgatttca tctaacttcc ttcgtctgga aaatggcggt gccttccacg
    37801 atggagattt gattgtggac gagttgatgc gcattataca ggtgaaaaaa tgagtttcac
    37861 agtagcagta aaagaagaaa tcctgggcca acaccatctg agctggcatg aattatctgc
    37921 cattatcaaa atgtctggta gcatcggtct ctcgacttcg ggcttgactt tgtcagttgt
    37981 gacagaaaat gccaaactgg cccgtcacct ctatgagtcc tttcttcatt tctatgaaat
    38041 caaatctgaa attcgtcacc accaacggag caatcttcgc aagaatcgcg tctataccgt
    38101 ttttacagat gaaaaggtgc aggatttgtt aagtgatttg cacttggcag actctttctt
    38161 tggcctggaa acaggtattg atgaggcgat tttatcggat gaggaagcag gtcgtgccta
    38221 tctctgtggc gctttcttgg caaatgggag cattcgtgac cctgagtcag gcaagtacca
    38281 gttggaaatc agttctgttt atctggacca cgcgcaagga attgcctccc ttctccaaca
    38341 gtttttactg gatgccaagg tgcttgagcg caagaagggg gctgtgacct atctccagcg
    38401 agcagaagac attatggact tcttgatagt aatcggagcc atgcaggcac gtgatgattt
    38461 tgagcgggtt aagattttgc gagaaacccg taacgacctc aatcgggcta ataatgccga
    38521 gacagctaat atcgctcgga cagtttctgc cagcatgaag accattaaca atatcagtaa
    38581 aatcaaagat atcatgggct tagaaaattt gccagtagat ttgcaggaag tggcgcaact
    38641 gaggattcag cacccagact actctatcca gcagttagca gatagtctca gcacccctct
    38701 gaccaaaagt ggtgtcaatc acagactcag aaaaatcaat aagatagcgg atgaattata
    38761 aagccacgaa tcctatgtga ctagtggttc ttttttataa actggtagag tgttttggtt
    38821 gtactttttg ttcagggtca atgtagttga tagcgttgtt gacagcagtt ggagcttctc
    38881 cgaggcctgt cgcaatcaga tcaatttttc cgtcatagta gcagcagtca ccgatagcat
    38941 agatacctgc ttggctggat tcctgtttgc tgttgacgat aatcttgtga cggttgaggt
    39001 tgagccccca gtttttaagg ttaccgacag aagatttgaa accatagttg acaaagaggt
    39061 ggtctaggtc aatggtttca gtttcatcag atttgacttt tgtgatttca agtttatcaa
    39121 gtgtttttcc atttccaagg agttggctag gggcgaatgg tgtcttgatg gttacagatg
    39181 attcttgcaa ggcttgaaca ctgtgttcca aggcacggaa attatctctg cggtgaacaa
    39241 gggtagttgg tgcgattttt tcaaaagcca aagcccaatc cacagccgag tctcccccac
    39301 caagaatcgt cactttctta ccagcgtatt gctgaatgtt agaaacgtgg tagtggatat
    39361 tttcatagcc ctcaacacct tcaagttcca gcggacgtgg tttgaaggca ccgccaccca
    39421 tagcgatgat gactgtttta gtcaggtgac ttcctttaga agttgtgatg gcaaattctt
    39481 cttcttgttt gtcaatctca agaaccgttt cattgagatg aataggggta tcaaatccat
    39541 ttagctgttc aatcaagcgg ttagtcaact cttctccagt caggtttggg aagcctggta
    39601 cgtctaggat ttccttttca gggtagagaa tagcaggttg tccacctagc tggggaagag
    39661 agtcgatgat ttgaaccttg gcttggcgta ggtgggcata aaaggctgca aaaagcccga
    39721 caggaccacc acccacaatg gtaatatcat agagttgaga catagtttct cctttgtttt
    39781 ttctagtcag tttattttat catatttttg ttcaatgtaa aatggactag gatagggaaa
    39841 aaaatgccag aaaatggtat aataggacga aagtgttttg atagggagga tatcagggat
    39901 gaattttcaa caattatcca atctgcaata ttggaccagt ttgtttgcaa gtccatggac
    39961 gatagctatc aatctgattg atattttgat tgttgcttat attttatacc attttacaaa
    40021 agctattgca ggaaccaaga ttatgatttt ggtacgtgga gttttggtgt ttattttagc
    40081 tcaaatcctt gcaaatatga ttggtttgac tacgatttct tggttaatca atcaaattat
    40141 tacttatggg gttattgcgg cggttgttat cttctctcca gagattcgga ctggtttgga
    40201 acgtttggga agagcgacag atttcttttc caatgcccct attagtgctg aggaacagat
    40261 gattcgtgcc tttgttaagt ctgttgaata catgagtcct cgtaaaatcg gggccttggt
    40321 tgctattcag cgtgtacgta ccttgcagga gtatatttcg acaggaattc ccttggatgc
    40381 taagatttct gcagaacttc tcattaacat ttttattccc aacactcccc tacatgatgg
    40441 tgcggtgatt atcaaagaag aacgtatcgc tgtgacgtct gcctatctgc ccttgacaaa
    40501 aaacacaggg atttccaagg aatttgggac cagacaccgg gcggctatcg gtttatcaga
    40561 agtctcagat gccttgactt ttgtcgtatc agaggaaacg ggaggaattt cgataaccta
    40621 taatggaagg tttaagcaca acctaacact tgatgaattt gaaacagaat tacgtgaaat
    40681 cttacttcca aaagaggaag tgggtcttag ttttaaagaa cgattgctag gaggatggaa
    40741 acatgaaaaa aaatagttta tatatcatat cctcactctt ttttgcttgt gtcttatttg
    40801 tctatgctac ggcgacgaat tttcaaaaca gtaccagtgc taggcaggta aaaacggaaa
    40861 cctatactaa tacagtaaca aatgtcccta ttgacatacg ctataatagt gataagtatt
    40921 ttattagcgg ttttgcttca gaagtatcag tggtcttgac tggtgcaaat cgcctatcgc
    40981 tagctagtga aatgcaagaa agtacacgta aattcaaggt tactgctgac ctaacagatg
    41041 ccggtgttgg aacgattgaa gttcctttga gcattgaaga tttacccaat gggctgaccg
    41101 ctgtggcgac tccgcaaaaa attacagtca agattggtaa gaaggctcag aaggataagg
    41161 taaagattgt accagagatt gaccctagtc aaattgatag tcgggtacaa attgaaaatg
    41221 tcatggtgtc agataaagaa gtgtctatta cgagtgacca agagacattg gatagaattg
    41281 ataagattat cgctgtcttg ccaactagcg aacgcataac aggtaattac agtggttcag
    41341 tacctttgca ggcaatcgat cgcaatggtg ttgtcttacc ggcagttatc actccgtttg
    41401 atacaataat gaaggtgact acaaaaccag tagcaccaag ttcaagcaca tcaaattcaa
    41461 gtacaagcag ttcatcggag acatcttcgt caacgaaagc aactagttca aaaacgaatt
    41521 aaaaatagaa aaggatttta taacaatggg taaatatttt gggactgatg gagtccgtgg
    41581 agaagctaac ctagaactaa caccagaatt agcctttaaa ctaggacgtt ttggaggcta
    41641 tgttcttagt caacatgaaa cggaagcgcc gaaagtcttt gtaggacgtg acacacgtat
    41701 ttcaggggaa atgctggaat cggccttggt ggcaggtctc ctttcagtag ggattcacgt
    41761 atacaaactt ggtgtccttg caacaccagc agtagcttac ttggttgaaa ctgaaggagc
    41821 aagtgccggt gtcatgattt ctgctagcca caacccagcc cttgataacg gaatcaagtt
    41881 ctttggcggt gatggcttca aactagatga tgaaaaagaa gcagaaattg aagccttgct
    41941 agatgctgag gaagacactc ttcctcgtcc aagtgcagaa ggcttaggaa ttttggtaga
    42001 ttatccagaa ggcttgcgta agtatgaagg ataccttgtt tcaactggaa ctcctcttga
    42061 tggaatgaag gttgccttgg atacagctaa tggagcagct tctaccagtg cccgtcaaat
    42121 ctttgcagac cttggtgccc aattgacggt tatcggggaa acaccagacg gtcttaacat
    42181 caaccttaat gttggttcaa cacatccaga agcccttcaa gaagtggtca aagaaagtgg
    42241 gtcagctatt ggtttggcct ttgatggaga cagtgaccgc ttgattgctg ttgatgagaa
    42301 tggtgacatc gtcgatggtg acaagattat gtacatcatc ggaaaatacc tttctgaaaa
    42361 aggacaattg gctcaaaata caattgtgac aactgttatg tctaaccttg gtttccacaa
    42421 ggccttgaat cgcgaaggta ttaacaaggc agttactgca gttggtgacc gctacgttgt
    42481 tgaagaaatg agaaaatcag gctacaacct tggtggtgaa cagtctggtc acgttatctt
    42541 gatggattac aataccacag gtgatggtca attatcagca gttcaattga ctaaaattat
    42601 gaaggaaact ggtaagagct tatcagagtt ggcggcagaa gtaacgattt atccacaaaa
    42661 attagttaat atccgagtgg aaaacgtcat gaaggaaaag gccatggaag tgccagctat
    42721 caaggccatc atcgagaaga tggaagaaga aatggcgggg aacggccgta tccttgttcg
    42781 tccaagtgga acagagcccc tcttgcgtgt tatggcagaa gcgcctacaa cagaagaagt
    42841 ggactactat gttgatacca tcacagatgt agttcgtgct gaaattggga ttgactaaat
    42901 cctagaaaac tagatgaaaa taaaaaatta tggtacaata gcttataata ttgtagccga
    42961 tggagaaaga catgaatctt aaacgtgaac aagaatttgt tagtcagtat cattttgatg
    43021 cacgtaattt tgaatgggaa aatgaaaatg gagctcctga aaccaaggtg gatgtgaatt
    43081 tccaattgct ccaacatgac caagaaaatc aagtgacttc cttgattgtc atcttgagct
    43141 ttatgattgt atttgataag tttgtcatta gtggaacaat ctcacaagta aaccatatcg
    43201 atggccgtat tgtcaatgaa ccaagtgaat tgaaccaaga agaggtggaa accttggctc
    43261 gtccatgttt gaacatgctc aatcgtttga cttacgaagt gactgaaatt gcattagact
    43321 taccaggaat taatttggag ttctaatatg aaattagctg ttttcacaga ttcctctgct
    43381 tatctcagtg aagagacctt gcaaagagaa gacttgtttg tcttggatat tcctgtcaat
    43441 attgatggtg aggaatatgt cgaaggcatc aatctgtctg ctgaggaatt ttaccaaaaa
    43501 atggctcagg cttctgaatt gcctaagacc agtcaaccaa gtattgccaa gttagatgag
    43561 atcttaactt cgctcaaaga acaaggctat acacatgcct tggggctttt cctatcttct
    43621 ggaatttcag gtttttacca aaatatccag tatatggtcg atgactatga gggcttaacc
    43681 attgctttcc cagacacttt gattacaagt gctcccctag gcatcatggt tgaaagcgtc
    43741 tttaattggc gtgatcaggg cgatgatttt gccagcattc aggataagct agccattcaa
    43801 atcagccgta cgtcagcctt tatcatggta gatgacttgg atcatttggt aaaaggtgga
    43861 cgcctttcaa atggggctgc cattttgggc aatttgctta gcattaagcc aatcctttat
    43921 tttaacgatc aaggtgtgat tgaagtttac gaaaaagttc gtactgaaaa gaaggccacc
    43981 aagcgcttaa ttgaaattat caaggaaaca acggcttcag gtcaataccg ggtcattgtc
    44041 attcatggga atgctcctga aaaggctgaa gaattgcgtc agcacttgct tgattttggc
    44101 ttgggttcgg atgtttcact tgctacattt ggtagtgtca ttggaacgca cctaggagca
    44161 ggaagtattg ctctgggtta tattccagtg atttagttgg cgcttctagg ctagttaaga
    44221 tgccttgtat cttagaaatt gaacacggac tacctgcctc ttgaaaaaag atgcctgtct
    44281 tgcctttcgt ggaaagtcag tgccattccc tatttttcag aggcagctaa ggtcctttgt
    44341 atcttgataa ttgaacacgc ctggaaccct gtgtgaaaaa gatagttctt ccaagaagta
    44401 gacacttctt gattggaatt cctattttca ctttgtgttc ttacggactt tgtatcttag
    44461 acaggagtag agatgagtat tcgagtaatt attgccggtt ttaagggaaa gatgggccag
    44521 gctgcttgtc agatggtatt gactgatcca gacttggact tggtggcagt tttggatcct
    44581 tttgagtctg agtcagaatg gcagggtatt cctgttttca aggataaggc tgatttagct
    44641 ggttttgaag cggatgtctg ggtagatttt actactccag ctgttgccta cgaaaataca
    44701 cgttttgctc ttgaaaatgg ctttgctcca gtagttggaa cgactggttt cacgagtgaa
    44761 gaaattgcag agctaaaaga attttctcgt gcccaagact tgggtggcct gattgcccct
    44821 aactttgcct tgggtgctgt cttactcatg caatttgcga cgcaggctgc caaatatttc
    44881 ccaaatgtgg agattattga gctccatcat gacaagaaaa aggatgctcc gagtggaaca
    44941 gccattaaaa cagctgagtt gatggcagag gttcgagagt ccattcagca aggcgcagca
    45001 gatgaggaag agctgattgc tggtgctcgt ggtgctgact ttgatggtat gcgcatccac
    45061 tcagttcgtt tgccaggctt ggtagctcat caggaagtca tctttggcaa tcagggagaa
    45121 gggctgaccc tccgtcatga ctcctatgat cgcatctcct tcatgacagg agtcaatttg
    45181 ggaattaaag aagttgtcaa gcgtcatgag cttgtctatg gattagaaca cttattatga
    45241 gattaacgca aatgccttct gaatttcaga aggctttacc agtattagaa aaaattaaag
    45301 aagcaggctt tgaggcttat tttgttgggg gctctgttcg agatgccctt ctccatagcc
    45361 ctatccacga tgtggatatt gcgacgtctt cttatccaga agagaccaag cagatttttc
    45421 cgcgaacagc cgatatcgga atcgagcatg gaaccgtctt ggtcttagat ggggatgagg
    45481 agtatgaggt aacaaccttt cggacagagg atgtctatgt ggactatcgc agacccagtg
    45541 cggtttcctt tgtacgatcg ctagaagaag acctcaaacg ccgtgatttc acagtcaacg
    45601 cctttgcctt ggatgagaca ggagaaatcg ttgacttgtt ccatggttta gaagatttgg
    45661 aaaagcaagt cttgcgagca gttggagtgg ctagtgagcg tttcaacgaa gatgctttac
    45721 ggattatgcg tggtttccgt tttcaggcta gtcttggttt tgcacttgag ccagaaacat
    45781 ttaaagctat gaagaccttg acgccgcttt tggagaaaat ttctgtagag cgtaccttcg
    45841 tcgagtttga taaactcttg ctggctccat tttggagaag gggcttggct tccatgattg
    45901 agagtcaagc ttatgactat ctccctgata tggcatctag ccaggacaag ctcaacagac
    45961 tgtttgattt ggagactgat tttacttttg aatcctctga acaagcctgg gcggctttac
    46021 tatgggcttt ggagattgaa aatgcgcagt cacttttgaa atcttggaag acctcacgcc
    46081 agtttgccaa gcaagttcag gatttgctga ttattttggc tctgcgtgaa aatggagaat
    46141 tgagcaagcg agattgttat cgctttgaca tagatttgct tttacaggct gaaaatcttc
    46201 gtcaagctca aggaaaagaa gtcaacccac aagccatcac agaaaaatac caaagcttga
    46261 ctatccatga caagaaagag attcagatta atggcggtat tttgatcaag gaatatggct
    46321 atcagccagg cccagacttg ggagagattt taacagagat tgagtttgcc attgtcgatg
    46381 gagaattgga gaataatcgt gaagccatcc atgcttacct gagggagaaa aaatgagtga
    46441 ttttatcgtt gaaaaactaa gtaaatccgt tggtgacaag accgttttta gggatatttc
    46501 ctttattatc catgacttag acagaattgg tttaatcggt gtcaatggga ctggcaagac
    46561 cacccttttg gacgtccttt ctggtgtttc tggatttgat ggggatgtca gtcctttttc
    46621 agctaaaaat gattaccaga ttggttactt gactcaggat cctgattttg atgatagaaa
    46681 gacagttttg gatacggttc tatctagtga actcaaggaa atccagctca ttcgtgagta
    46741 tgaattgatt atgctcgact atagtgagga caagcaggcg cgtttggaac gtgtcatggc
    46801 agagatggac tctctccaag cttgggaaat cgaaagtcag gtcaagaccg ttcttagcaa
    46861 attgggcatt caagacttat ctactcctgt tggggaattg tcaggtggtc tgagaagacg
    46921 ggtacagttg gcacaagtct tacttggcaa ccacgacctc ttgcttttgg atgagccgac
    46981 caaccatctg gatattgcga ttattgagtg gctgaccctc tttttgaaaa attctaagaa
    47041 gaccgtcctt tttatcactc acgatcgtta tttcttagac gctttgtcaa cacggatttt
    47101 cgagttggat cgtgcaggct tgaccgagta ccagggaaat taccaggact atgttcgcct
    47161 aaaggcggaa caggatgagc gcgacgcggc tcttcttcac aaaaaagaac aactctacaa
    47221 acaagaattg gcctggatgc gcagacaacc gcaggcgcgt gcgaccaagc agcaggcccg
    47281 tatcaatcga ttccatgatc tgaaaaagga agtttcaggc agtagtgctg agacagactt
    47341 gaccatgaac tttgaaacca gtcggattgg gaagaaagtc atcgagtttc aggctgtttc
    47401 ctttgcctat gaaaacaagc ctattttgca agattttaat ctcttggtgc aggccaaaga
    47461 ccgtatcgga atcgttgggg acaatggtgt tggaaaatca accctgctca acttgattgc
    47521 aggaagtctt gagccaacta aaggacaagt tgtgattggg gaaactgttc gcatcgccta
    47581 tttctctcag caaattgagg gtttggatga aagcaagaga gttatcaatt acctgcagga
    47641 agtggcagaa gaggtcaaga ccagtggcgg ttctacgact tcgattgcag agttgctgga
    47701 gcagttcctt ttcccacgtt cgacgcatgg aaccttgatt gagaaattgt cagggggtga
    47761 gaaaaaacgt ctttatctcc tcaaactgct tttggaaaaa ccaaatgttc ttcttttaga
    47821 cgagccaacc aatgacctag atattgcaac tttgacagtc ttagagaatt tcttgcaagg
    47881 ttttgcaggt cccgttttaa cagtcagtca cgaccgctat ttcttggata aggtagcgac
    47941 caagattctc gcttttgagg atggcaagat tcgtcctttc tttggtcatt acaccgacta
    48001 tcttgatgaa aaagcttttg aaacagatat ggccaatcaa gtgcaaaagg tcgaaaagga
    48061 aaaagtggtc aaggttcgag aagacaagaa acgcatgacc taccaagaaa agcaggagtg
    48121 ggcaagtatt gaaggtgata ttgaaacctt ggaaaaacgt atcgctgcta ttgaagagga
    48181 aatgcaggct aacggctctg actttggtaa gctggctact ctccaaaaag aattggatga
    48241 gaaaaatgaa gcactccttg aaaaatacga acgctatgag tatctcagtg aatttgatag
    48301 ttaagactat tcgaaaatca aagtgcaaac tatgtcggct tcacattgcc gactcaagta
    48361 cagcctgtga ccggcttcct aatttgcact ttgattttta ttgagtataa aagaatagaa
    48421 aaatcccgtc tcatgaaagg atttctctat tcttttttgg tttcttgatg aaagatattt
    48481 tgccaggttt cgtggcgacg ccagatactg gtatggatga taccatctaa ctcatagcag
    48541 atgagtttgg ttttttgact gatggaagta atttgaatgt cctttatagc agaatttaac
    48601 tcttttttgg tcttataagc ctctttatcc atctgctctc catcttggcg aatatagaca
    48661 aaatcatcag tcaagagttc ttctagttgg tttccttggt caatcaattg ttcacgcata
    48721 agcaattttt tatagacatt gtctaaaatt tcatcctcag ggataggtgc tggttcgata
    48781 tggacatcgg tatcaaagac gccaaaacgc tcctccagca tagactcgac ctgatccgcg
    48841 atttcatggc tttcaaaaac agacaagtca ggattcatct ctagtgtaat atccaggtag
    48901 atgttgctac cgtaggtgcg acctctttgc gatttgacct tgctgatttt gggaatttcc
    48961 atgatagcct tttggtagtc ctcgagcagg cggtcgtcaa agccatctga aagactaaag
    49021 gaagactcga tgaagatatc ataggcagtc ttcaagataa agaaagtgat gatgatagca
    49081 accagtttat ccacaatcgg ataattgaaa ctactagcta ggatggcaat ggcggttcca
    49141 agtgaggtaa cagcgtcaga aagattgtcc ttagcagctg ccttcagcgc cttggagttg
    49201 gatttcttac tgaggcgagt attgtagaga tagaccacaa acataatcgc tgcagaaatg
    49261 attcctagag ttgcaccaag aggatcaatg accgtttctt cccgactgag aatcttttga
    49321 atggtatctc ttagaacatc gaaaccgaca tagaacatga tgatagaagt gatcaagctt
    49381 gccaaatctt caatcttcca atgaccaaaa cggtggtcac ggtctgcagg ctggcgcgcc
    49441 atccgaatcc cgattaagag ggccacattt ccaatgatgt ccgatacgtt attaaaacca
    49501 tcggccacca aactggatga atgaaggaga tgaccagctg ctaatttagc tgcagacaag
    49561 atcaaatagg tcgaaatact gataatggct ccacgctcag ctaacttgag atttgagata
    49621 gattgcttca ttcaacttcc tttctagtca catagcattc taccattata ctggttttca
    49681 aggaaaaatt caaataaggc agtttttact ctttgaaaac tccccaaaat ttggtataat
    49741 ggtactactc aagggagtag ctggcagaaa cctgtgatag tgtcgtcatt ccgaatttta
    49801 tgctgaaaag tatgctttcc ggccctatct taaacagcga gacttgttat gattaacagg
    49861 tctctttttg tttgtcgtga aaagatatga cagaaagaga gtctgttttg cacacaatgt
    49921 caaggaggag acacatgtca aaagaacaaa aacgccaagc gttttatact cagagccctg
    49981 aagaggtctt gcaggctgtg gatgcgaccg agcaaggttt gtcatcaagt gaggcggaaa
    50041 agcgccttgc cgaatttggg cacaatgaac tcgaagaagg cgagaaacga tcaatcttgg
    50101 tcaaattcat cgagcaattt aaggatttga tgattatcat cctagttgcg gcagcaatct
    50161 tgtcagtcgt gacttctggt ggggaagata tcgcagatgc cattatcatc ctagctgtgg
    50221 ttatcatcaa cgctgccttt ggtgtttacc aagaaggaaa agctgaagaa gctattgaag
    50281 ccctcaaatc catgtctagt ccagttgccc gcgttcttcg tgatggacac atggcagaga
    50341 ttgactctaa agaattggta ccaggcgata tcgttgccct tgaagcaggt gacgtggtac
    50401 cagcggacct acgtttgata gaagccaact ctcttaaaat tgaagaagca gccttgacag
    50461 gtgaatctgt accagtcgaa aaagacttgt cagtcgagct tgcgacagat gctggtattg
    50521 gtgaccgtgt caacatggcc ttccaaaact caaacgtaac ctatggtcgt gggatgggtg
    50581 ttgttgtcaa tacaggtatg tacactgaag ttggtcatat tgctggtatg cttcaagatg
    50641 cggatgagac tgatacacca ctcaaacaaa acttgaacaa cctttctaag gtcttgacct
    50701 atgctatctt ggtcattgcc cttgttactt ttgtagtggg tgtcttcatt caagggaaaa
    50761 atccacttgg tgagttgttg acttctgttg cccttgccgt tgcagccatt ccagaaggac
    50821 ttcctgctat cgttaccatc gttctttctc ttggtactca agttttggcc aaacgacatt
    50881 ccatcgttcg taagttgcca gcagttgaaa cacttggttc aactgaaatc atcgcttctg
    50941 ataagactgg tacgctgact atgaacaaga tgacagtcga aaaagtcttc tacgatgcgg
    51001 ttctacatga ctcagctgat gatattgaac taggtcttga aatgccacta cttcgttcag
    51061 ttgtcttggc caatgatacg aaaatcgatg tggaaggtaa cttgattggt gacccaaccg
    51121 aaacagcctt tatccaatat gccttggaca agggctatga tgtcaaaggt ttcttagaga
    51181 aatatcctcg tgtagctgaa ttgccatttg actctgaccg taagctcatg tcaacagttc
    51241 acccattgcc agatggtcgt ttccttgtag cagtcaaggg tgcgccagac caactcttaa
    51301 aacgttgtct tcttcgtgat aaggctgggg atattgctcc gattgatgag aaggttacaa
    51361 atctcattca tacaaacaat tctgaaatgg ctcatcaagc cttgcgtgtc cttgcaggtg
    51421 cttataagat tatcgatagt attccagaaa atctcacttc tgaagagctt gaaaatgatt
    51481 taatttttac tggtttgatt gggatgattg accctgaacg tcctgaagcc gctgaggctg
    51541 ttcgtgtggc taaggaagcg ggaatccgtc caattatgat tacaggtgac caccaagaca
    51601 cagcggaagc cattgccaaa cgtttgggaa tcattgacgc aaacgataca gaaggtcacg
    51661 ttttaactgg tgctgaactc aatgaactgt cagatgaaga atttgaaaaa gtcgttggtc
    51721 aatactctgt ttatgcccgt gtgtctccag aacacaaggt tcgtatcgtc aaggcttggc
    51781 aaaaacaagg taaagtcgtt gccatgacag gtgacggtgt caatgacgcg ccagctctga
    51841 aaacagccga tatcggtatc ggtatgggaa tcactggtac agaggtttct aagggggctt
    51901 ctgatatgat tcttgcagat gataactttg cgactattat cgtcgcagtg gaagaaggac
    51961 gtaaggtctt ctcaaacatt caaaagacta ttcagtacct actttctgct aatactgctg
    52021 aagtattaac catcttccta tcaaccttgt ttggttggga tgtcttacag ccggttcatc
    52081 ttttgtggat caacttggta acggatacct tcccagctat cgctcttggt gttgaacctg
    52141 cagaacctgg tgtcatgaat cataaaccac gtggacgcaa ggcaagcttc ttctcaggtg
    52201 gtgttttgag ttctatcatt tatcaaggtg tactccaagc agctcttgtt atgagtgttt
    52261 atggccttgc gattgcttac ccagttcatg tgggtgacaa tcatgctatt catgcagatg
    52321 ccctaacgat ggcctttgca acccttggtt tgattcagct cttccatgcc tacaatgtca
    52381 agtctgtcta ccaatccatc ttgacagttg gcccattcaa gtctaagacc tttaactggt
    52441 ccatcttggt atcctttatc cttctcatgg caacaatcgt tgtagaaccg cttgaaggaa
    52501 tcttccacgt aaccaaacta gacttgtcac aatggggaat tgttatggct ggaagcttct
    52561 caatgattat catcgtcgaa atcgttaagt ttattcaacg caaactcggt tttgacaaga
    52621 atgcgattta agggaggttt cggatgtcag catatcaatt accgaccgta tggcaggatg
    52681 aagctagtaa tcaaggagct tttacggggc taaacagacc aacagcaggt gcccgtttcg
    52741 aacaaaactt gccaaaagga gaacaagctt ttcagcttta ttcactggga acaccaaatg
    52801 gtgtgaaggt tactatctta ttggaagaat tactagaagc tggttttaag gaagcggctt
    52861 acgacttgta taagattgct atcatggatg gggatcaatt cggctcagac tttgtgaagc
    52921 tcaatccaaa ttccaagatt ccagccttat tggaccagtc aggtactgaa aacgtaagag
    52981 tctttgagtc tgctcatatt cttctttacc ttgctgagaa atttggagcc tttttaccaa
    53041 gtaatcctgt ggaaaaggta gaagttttga attggctatt ctggcaagca ggtgcagcac
    53101 cttttctagg tgggggattt ggacatttct tcaattatgc tcctgaaaaa ttggaatatc
    53161 ctattaaccg ttttacgatg gaagtgaaac gccagttgga tttattggat aaggaattgg
    53221 ctcagaaacc ttatattgca ggcaatgact atacgattgc agatattgct atctggtctt
    53281 ggtatggaca gttagttcaa ggaaatcttt accaaggttc tgcaaaattc ttggatgcct
    53341 caagttatca aaatctagta aaatgggcag aaaaaattgc caatcgtcca gctgttaagc
    53401 gtggattgga agtaacttat acagaaatta aatagcaaaa aagtcatctt cggatggctt
    53461 tttgctacag ttgagggaaa gggtttgcag ttatcggctt ttgtgctata attgctataa
    53521 tatagtaaaa agcaagagga gtgtgaggaa gtggaaaaga aaattgtgaa ggatatctta
    53581 tttttatctc aagtgtctca gccggcaagt caggaggacc tttatcttgc cagagatttg
    53641 caggatacac tcttagcaaa tcgtgatacc tgtgttggtc tagctgccaa tatgattggg
    53701 gtgcagaagc gcgtgattat ctttaatctt ggcttggttc ccgtggtcat gtttaaccca
    53761 gtgcttctgt cctttgaagg atcttatgag gcagaagaag gctgtttgtc cttggtaggt
    53821 gtgagatcaa ctaagcgtta tgaaaccata aggcttgcct atcgtgacag caagtggcag
    53881 gaacagacca ttaccttgac aggcttccca gctcagattt gccagcatga gctggatcac
    53941 ttggaaggac gaatcattta ggaggaaagc aaatgaaacg aatagtcttt gaacttattt
    54001 ttatcgcaac gacctggtat atctttttac cgccccttaa cctgaccagc tgggaatttc
    54061 tcttcttcct ctgtgggcat ttgttagttg tggcaatctt atttggcttt ggcaagggga
    54121 taaaccttgt caaaacggtt catgtgcgcc acggtaaggc ggaagctgcc ttaaatcttg
    54181 agggtttcaa aatcaatcgg ttagggaaaa ttctgttagc ttcgattgga ggaattcttc
    54241 tcttggcagc tttggtttcc ttggtaactt ccagcatgtt tcaggctaaa aattatgcca
    54301 atgtagtcac agttacggaa aaagacttta ctgaatttcc taagagtgac accagtaagg
    54361 ttcctatcct agatagaagt actgctgaaa aaattggaga ccgctacttg ggttccctaa
    54421 ccgataaggt gtcgcaatac gtagcggcag atacctatac ccaattgaca attgatggga
    54481 aaccttatcg ggtcacacca ctagaatatg cagaccctat caaatggttt aacaatcaag
    54541 ccaagggaat cggtgagtat attaaggtgg acatggtaac tggaaatgcg gatttggtgg
    54601 acttgaagac accaatcaag tattcagact cggagtattt taaccgtgat gtcaaacgtc
    54661 acctgcgctt gaagtacccg accaaaatct ttaaaactcc atcttttgag gtggacgatg
    54721 agggcaatcc tttctatgta gcaacggttt accaaaagca atttggactt gctgttcctc
    54781 gtcctgcttc agtcattatc ttggatgcta caaatggaga aaccaaggaa tacagcttat
    54841 cagatgttcc agaatgggtg gacaggatct atccagcaga ggaaaccatt gagcaaatca
    54901 actacaacgg caagtacaag gacggtttct tgaatgccat gatttccaag aaaaacgtga
    54961 cccagactac caatggctat aattacttgt ctatcggtaa tgacatctat ctctacacag
    55021 gtgtgacgtc ggctaatgcg gatgagagta atcttggttt catccttgaa aatatgcgaa
    55081 caggagaaat cactaagtat agcttggctt ctgcgacaga agaatcagcc cgtgaatcag
    55141 cagaaggtgc tgttcaggag aaatcctaca aagcaacctt cccaatcctc atcaacctca
    55201 atgacaagcc tctctacatc atgggcttga aggacaatgc tggcttggtc aaagagtacg
    55261 ccctggtaga cgcagtcgag taccaaaatg ttatcgttgc tactacagtg gaagagatgc
    55321 tcagcaagta tgccaataaa aacgaccttg aaattgacaa tgcaacgaca gaaagcatca
    55381 agggagtagt agcagacctc aaatcagctg ttatcaaggg agacactgtc tacttcttta
    55441 aagttgatgg caagatatac aaggtcaagg cttcagtatc cgatgacctt ccttaccttg
    55501 aaaatggtaa aaccttcgaa ggtcaagtag gaaaagacaa ttatctcaag acctttaagc
    55561 tacggtaaaa ataggttttt tcagaaagta tatgttataa tagagtaaat taagactaat
    55621 ggaggacaaa gaaatgggtt tttatttgat ggttgcttca atgctactcg gactgctcgc
    55681 tttgaagata ggtttttctc agttcaagga gaaaaaagat aaattcttat ctatcttaac
    55741 aagtttagct ggcacagccc ttgttctcgt ggctgtctgg ttaggatggc ccaaataaat
    55801 agaaaaacct cggtcaaacc gaggtttttc aaatgaattt cttggttgtg gctaaaaaat
    55861 atgctacact atcaatatga aaattttaat cccaacagca aaagaaatga acacagactt
    55921 gccaagtatc gaggcaattc ctttaaaacc agaaagtcag accgtgcttg atgccttggc
    55981 tctctattct gccagtcaat tggagagttt ctacaaggta tcagctgaga aagcggcgga
    56041 agaatttcaa aatatccaag ctttgaaaag gcaaactgct caacactatc cagccttgaa
    56101 actttttgat gggcttatgt accgcaacat taagagagat aagctgaccg aggcggaaca
    56161 agattatctt gaaaatcatg tcttcattac ctcggctttg tacggtgttg ttccagcctt
    56221 gtcacccatg gctcctcacc gtttggattt tttgatgaaa ttaaaagtcg ctggtaagac
    56281 tttgaagagc cattggaagg cagtctatga tgaagctctg aagaaggaag aagtgatttt
    56341 ctctctcttg tcatcagagt ttgagactgt attttctaag gaaatcagag caaagatggt
    56401 gaccttcaaa ttcatggagg atagaggcgg tcagctgaag attcactcaa ctatctccaa
    56461 gaaagcgcgc ggggcctttc taacagcttt aatagaaaat caagtacaaa ctgtggggga
    56521 agcacgtcgc ttgaactttg ctggatttgt ttaccgagaa gatttgtcac aaccacaggg
    56581 attggttttt gtaaaggaag tatagaaatc agataagaga aaagtcagca cgattatgct
    56641 gacttttttg ataacttata aagtattgga caaatgaatc tcatttgata aggtgttaag
    56701 atgattaacc aaatttatga ttgacagatg atttcggcaa ataaacttct tggtaatccc
    56761 tggaatatag aaattagaca cgatgatatc gtaatctgtc tgatttaaaa tctcaggact
    56821 tgtttttaat tcatcccaaa tatcgaaggt aaagcggtta ttacagtaat aggaaagcat
    56881 atcaacaaag gtaagggata tagcatggtc aaagttactg ataatcaaaa ccttgatagg
    56941 tggtcgattt tctaacaact gagtagagag gttttcagca tgggttaaga tggtgtacat
    57001 caagtgttcc aactgttcag gatggtcatg ctgtccaatt gcctgacggt attgagccaa
    57061 ttcttgacgc gcacttccca taaagtctgg gaagtaaact tcaaattttt taatcgtcaa
    57121 tgctttttgt tcaaataaga ttggggtaga aaagatttcc tgtctttcaa agaaagcagt
    57181 gttgtgtaaa tgccaaatca gctcatcgtg gttagtaaaa gtaatcttat attgttttga
    57241 taggcgttct aatatttgac taagtaattg gtaagagtat cttgcttgac tgttatcttc
    57301 taaagagttg aagaattctt gaggatctag gaaaatatca ttctgaagaa aagaaataaa
    57361 aatttgagcg attgtatctg gagtcatttc aagcccaaaa tgtttagaga aataagcaag
    57421 tgtctcctgg aaatttggaa tgctctttaa aagcggataa tattctttgt aaaagtggtt
    57481 ggggaggtca atgaagtgac catttttaac cctgtggata ctgatagcta tcatcagttt
    57541 gtacattcta taaattgaaa atcgcattgg ataattcgtg attttataga agaagtcagc
    57601 aaactctgtt aaatcttcct caggaaggtc aggaaaaggc caatctagga aataatagcg
    57661 ctcagaaaag tattgggcaa aaaagtaacg aatatcgatc tcatttccac gtatctcgga
    57721 tggagtaaaa gataattcaa tttgaaactg agatgaaaga acctttgtaa tatttctgcc
    57781 cagtcgatag aggttggcac tactaaagta aagattttct attgttcgat aaataggtag
    57841 cccctcattg aagaacatat actctagtaa ttgaaaagat tgagaattag caagaaaata
    57901 ttgataaata tcttctacac tagtgttaac ttctaaatct atcatgattc cgttaacaga
    57961 agattggatg ttaatagatg gaaaggcaat acgtaattca tttaaatcac tttttaagat
    58021 tcgttctgtg catcctaatt tttcggctag ttcatgtaat ttcatccaat tacgattctg
    58081 aattaggttt tccattaagc gtaattgtct ttgaactttt gtggataaaa ggtttctcat
    58141 acgggtattt tctccataat tcattatatc tttttttgtc taagtagtat aaaaaaatta
    58201 gagcaagaaa attgtcgtta gtaatcggaa aaattagaat aatataagtg gcttttaagt
    58261 gcaaaaacag aatatattaa ttgttcagaa aatattgatt aatgcctcaa atagttgtac
    58321 attgtaaact ataaaatact atctaggagt ttaaaatgaa acattcacat aaaaaatcat
    58381 ttgactggta tagcatgcaa caacgttatt ctattcgtaa gtattacttt ggtgcagtta
    58441 gtgtcttgct cggtaccgct ttggtattag gtgcagcagc tagtgtccaa acagtacaag
    58501 cggaagaaaa caaacaagaa actaccaata gtatttctgt tggtagggga gaagcagcta
    58561 ctaaactagc agaggtttct gcgtctaata aagagaaaac ctatgcagct ccaactgtag
    58621 ctaatccagt agaaacgact ccagttaaaa ctggagaagt tactaaacca gcagaaaaag
    58681 ttgaagaagc aaaagacaaa aaagaggaag taacgcatca agatgctatt gacaagtcaa
    58741 aattgttaac ggctctttcg cgtgctaaaa agttagaaag caagttatat acagaagcaa
    58801 gtgctgctaa cttgcaaaca agtatccaag ctggtcaaag cttgcttggg aaagcagatg
    58861 catctgaagc tgaattatca gcagcagagt catctattca atcatctatt attggtctag
    58921 aacttcgttc taactctaac aaaggaactg tatcagaaac tcctgtagcg aagaaagcta
    58981 atatagttga agcgaaggaa gagactaatc cagctgcaac aactgatcgt tcagctgttg
    59041 atagtgctgt tttgccaact agcacagctg ccaaagtaga aacaacttca gctccagcat
    59101 ctattaatga aatcttgaaa ccaggtttga gcctttctga tgctcgccaa aatccagcta
    59161 tccgtaaaga agacttggat aaggggtata gtggttttag agcagcacct gctccaacga
    59221 acaaactagt aactaatcta ggaaataata ctgttttcac tgatattagc agagggtctc
    59281 atactttccg tggtaatggg aattcacgtg gtggaaaccc gattcatttt gatgtaacaa
    59341 caactagagt tggaaataga gtagaattct caattgcata ttctggtcca ggtgagttcg
    59401 ttaataataa ctttctctta gacaaaggga atggatttgg agaaccatct cgtgcaacta
    59461 tttcaacaaa cagattaaga gatcaaacta aagatataag aaagggtgca aattttgtat
    59521 ctcattcaag ctacagttta acatctgctg ttgaaacaaa cagtaatcaa actattagat
    59581 ttagtttacc tatagccaac cctaatggtg atctgtctgt tcgattaaga cctgttactt
    59641 ttaatgtagg tcaaggggaa tcaggatctg caactagtaa tgatccatat agtaactcta
    59701 actattactt cagagaaaaa ccactcctct tggatgcaaa tccaaatggt ggtactaata
    59761 ataagactgt ttcagaagac attgacttcc aaactgtcta tcttccaact agtaagttac
    59821 cagaaggtca aactagatta gttcgagaag gtgaaaaagg acaacgtcaa atcatctata
    59881 aagttcatca attgggtaac gaaacaatcc taggattgcc aattagtaat tcagttatta
    59941 aagaagttaa gccacgtatt atgcaaattg gtgtggctaa agatctaatc gatacagtaa
    60001 aaccacgtgt tgatcaaaat aaagtcggtg atacaaataa cctcactttc tatcttgata
    60061 acgatggaaa cggtgtttat actgagggcg tagacgaact tgttcaaaaa attgctatta
    60121 aagatggtgc taaaggtgaa aaaggagtcc aaggcgaacg cggcctgact ggagcgcaag
    60181 gtcaggcagg tcgtgacggt gtaactccaa ccgtaaccgt taaagataat aaaaatgacg
    60241 gcactcatac tatcactatt aacgacggta gaggtaatgt tgcaagtact gttgtaagag
    60301 atggtttcga tggcgcaagt ccattagttg cgactcaacg aaatgaagca gataagacaa
    60361 caactgttat cttctattat gatcaaaatg gaaataatga attagatgct tctgataaga
    60421 aattaaaaga agttattatt gcagatggtg ccaaaggtga acaaggtctt caaggtcgtg
    60481 atggagctca aggaccaaaa ggagaacaag gtaatccagg aactccaggt aaagatggaa
    60541 aatctctaat tgctgttaaa aatggaactg aaacaaaagt atatgtagag gatccggcta
    60601 gaccaggaca accacttaat ccaaaccaac cattagcaac tatcactgat ggaagaaatg
    60661 gtactaatgg acaatcacca acaattacag cgacacgaag tgttcaaaat ggtaaaaatg
    60721 gtgtattagt aacaattaca ccagtaggag gtcgtccaca aacaacattt gtagaggatg
    60781 gacaaaaagg tgctgatggg aaaaccccaa cagtaacaat aactgagggg caaaacggca
    60841 cacatacatt aacggttcat aatccaggaa gtccagatgt gacaactacg atccgtgatg
    60901 gagctacagg acaagcaggt cgtgatggta aagatgtatt aaacggaaaa gtaaatccac
    60961 aaccaaacca aggtaaaaat ggagataaat atattaatac cgaaaccggt gatgtctatg
    61021 ttaaaaacaa tggaaactgg gataaagaag gcaacatcaa aggccctaaa ggggacaaag
    61081 gtgcagatgg tgctaaaggc gaaaaaggag accaaggcga acgcggccta actggagcgc
    61141 aaggagctaa aggtgcggat ggcgcagtag gtcgtgatgg acgtgacggt aaagacgtgt
    61201 tgaacggcaa agctaaccca gaagcacatc aaggtaaaga cggcgataaa tacgttaata
    61261 cagaaacagg cgacgtcttc gttaagaata acggcaactg ggataaagag ggcaacatca
    61321 aaggccctaa gggtgacaaa ggtgaacgcg gagaagatgg taagactcca gaagtaactg
    61381 taactccagg taaagatggc catagtactg acattacatt cactgttcca ggtaaagatc
    61441 cagttacagt aaatgttaag gacggagaaa atggtctgaa cggtaaaact ccaaaagttg
    61501 atttacttcg tgtccaagga aaaaacggaa atccatctca tacaattgtg acattctata
    61561 cagatgaaaa caatgacggc aaatatacac caggaactga tgaacttcta ggttcagaaa
    61621 tgattaaaga tggtgctaaa ggcgcggacg gacgagatgg taaatcattg cttactgtca
    61681 aggatggtaa agaaactaaa gtttaccaag aagatccagc taacccagga caaccattaa
    61741 atccagaaaa accacttgcg gtaattagag atggagtaga tggaaaatca cctacagtta
    61801 cagctgttcg taaagatgaa gcagggcata aaggtgtaga aatcactgtt gataaccatg
    61861 atggttcaca accaactaca gtctttgttc aagatggtgc taagggagaa actggtgcaa
    61921 tcggtcagga tggacaaact cctacaatca ctactcaacg tggacaagat ggccaaagca
    61981 ctgttgtaac tatcacaaca ccaggtaaag atccagtaac cttcactgta aaagatggta
    62041 agaatggtaa agatggccgt gcaccgaaaa tcaaagtaga agatattact tcaccttcaa
    62101 gaattagacg cgctacagat gctgctgcaa ctccaacgcg taacggtatc cgtgttacag
    62161 tttatgatga tgttaatgac aatggggtat acgacggagg tgtcgataaa gtattaaata
    62221 gtaaagatat ttataacggt atagatggac gtgatggttc agctccaact attactacaa
    62281 aagataatgg agatggaaca cacactatca cagttcaaaa tcctgatggt tctgaatcaa
    62341 caactgttgt taaagatggt aaagacggta aaactgcgaa tatcactaca acagaaaacc
    62401 cagatggaag ccacacaatt acggtgacaa atccagatgg ttcaactaaa gaaactgttg
    62461 ttaaaaacgg taaagacggt aagactccta aagttgaagt aacggataac aacgatggaa
    62521 ctcacacagt taaagtgacg gatggagacg gtaatgtaac gaacgctatc atcaaagatg
    62581 gtaaagatgg taaagctgca acagcaacaa ctactgaaaa tccagatgga agccacacag
    62641 taacaatcac taacccagac ggaactaaga atgagtttgt tgttaagaat ggacgtgacg
    62701 gtgttgacgg acgtactcca accgcatctg ttcgtgataa tggagacgga agtcatacaa
    62761 tcgttattac aaatccagaa ggtgtgacaa ctgaaaccac agttcgtgat ggtaaatcac
    62821 caaaagtgac tataactgat gaacaaaatg gaactcataa gatctctgtt ctaaatggtg
    62881 acggaacaac tactgaaaca atcattaaag atggtaaatc accagtagca acagttagag
    62941 ataaccaaga tggtacttac actattcgtg tggaaaatgg taatggtact gtttctgaaa
    63001 ccacagttcg tgacggtaaa tcaccaactg ctaaggttgt ggataacgga gatggaacac
    63061 acactatcac agttgtgaac tcagacggaa caactacaac aactacagtt cgttatggta
    63121 gagaaccaaa acttgaagtt attgataaca acgatggttc acacactatt aaagtgacag
    63181 gtgctgatgg taaagaaacg acaactacaa tctttgatgg taaatcacca aaagcgaaca
    63241 tcgttgataa cggagatgga actcatacat taacaatcgt agattctgat ggtcgtgaat
    63301 acaaatctat tattaaagat ggtaaagacg gcaaagatgg cgtttcacca actgtaactg
    63361 ttgaaaataa taacgatgga actcacgttg ttacaatcac taatccagat ggaagtaaga
    63421 cagaaatggt gattaaagac ggtaaagatg gtaaatcacc aaaagtttct gttgaagata
    63481 atggtgatgg tagtcataca atcacaatca tcaattctga tggaactgtg acaaaaacag
    63541 ttattaaaga tggcaaagat ggtagagatg gacgtgatgg tagagacggc aaagatggaa
    63601 aatgtggatg ccaagacaaa ccagtaacac catcaaatga caaaccagta cctccagcac
    63661 caaatgtgcc gacaccagaa gtactggtta aacctgtgcc agcgcaacca acaccaaatg
    63721 taccgacacc agaagtgcca gtacaaccaa ctccagctgt tccaacacca gaagtaccgg
    63781 ttccagaaca accagtagta ccaacaccgg ctcaaccagc aactccagta aatgctaatc
    63841 cagtagcacc aactacaggt aaagaaaacc gtggggataa attacctgaa actggaagcc
    63901 aatctgatta tatctctgtt cttttaggta gcggtattct attgagccta tatgtaggac
    63961 gaagaaaaga agattaatca gccaaaagca gtcactaatt tctcgaaaga agatgataag
    64021 tgatagatct cgaatgaaag aatattctta gaatgatttt cctatgatgg aaaagactgc
    64081 taaaaacctt gagtggtaac gctcaaggtt tttttggatg gctgatgttt gtctgaaaat
    64141 cttgattgag aaataaaaag ccaccctatt aggtggctat aattgattta gactttctaa
    64201 aattttctat tttttactga atcgcttcga ccaagtcttg agcttgtttt tcaagtgagt
    64261 ttaggactgt ttcttcaaga accaattttc cgtctgccca ggcagagtca ttaacacgtg
    64321 cagcagtgaa atcaccaacg ccttgtgtac ggataaatgg caagaggtct ttgtagatag
    64381 cgaaaagttg atcgtgccct gcattggcta cagatgatac tgtgacaaac ttgtcttgaa
    64441 gggcagaagc gccacgtgta tcagacaagt caagggcacg agatagccag tcaagcaagt
    64501 tttttactgt accagggata gagaagttgt agactggaga gaaaatccag atagcatccg
    64561 caacgagaac tgcttcacga gcagcagcta cagctggatg tgttggaact tccaaatctt
    64621 ggctgaagag aggaagggct gaataatcaa ggtagctaac ttccgcttta ccagcaagtg
    64681 ctttctcagc ttcgagcgcc atttggtggt tgaaagaacc ttgacgtagt gatccgacga
    64741 taaataatac ttttttagac atgatgtgtc tcctttttct tcaaatttcg agaactctct
    64801 cgttgttata aaatatatta caacaaaaca aaagaacttg caagaaattt gctcagagtt
    64861 tatttgaaaa ttgtaaaatt tcggaaactc tagtcatttg tgactgaaaa agtaagaact
    64921 gtttcacttt caaaatcggt tttgtttgaa gggagaaata gaattggttg ctcaaagcac
    64981 agctttgagg ttgcagataa agctgacgtg gtttgaagag attttcgaag agtattctta
    65041 tattcacttg taataaagct taatagatgg taaaatagac gagtgaaaaa aagacaaaac
    65101 aaagcaaaaa ataatctact gtggcagtat ggtctaggga tgacgatttt gtttgtggtt
    65161 atcagtgctt cctttctgta tatggtttct cttagcatga aaccctatca aacagctaaa
    65221 agtgaaggag aaaaattagc tcagcagtat gcaggattag agcaggccga tcaggttgat
    65281 ttatacaatg gcttggaatc ttattacagc gttcttggtc gtaataaaca gcaagaagca
    65341 cttgctgttc tgattggaaa agatgatcat aagatttacg tttatcagct aaatcagggt
    65401 gtttcacaag aaaaagcaga aacggtttct aaggaaaagg gagctggcga aattgacaag
    65461 attatctttg gtcgttatca agataagcca atctgggaag tcaagtcagg atctgatttt
    65521 tatctagtag attttgaaac aggagcattg gtcaacaagg agggcctatg aaattatcca
    65581 accgtgtttt agaaatggaa gaaagtgtga ctttggctgc tggagcccgt gccaaagcac
    65641 tgaaggctga gggcagagat attttgtctc taaccttggg tgagccagat ttcactactc
    65701 ccaaaaatat ccaagatgcc gccattgcat cgattcgaga tgggcgtgct tctttttata
    65761 cagtaacctc aggtctgcca gagcttaagg cggtggtcaa tagctacttt gagcgctttt
    65821 acggctattc tgtagcgtca aatcaagtga cagtcgctgc gggagccaaa tattctctct
    65881 ataccttctt tatggctgtg gtcaatccag gtgatgaagt catcatccca accccatact
    65941 gggttagcta tggagatcag gtcaagatgg cagaaggcgt tcccgtcttt gtttctgcta
    66001 aggaagacaa tcactttaag gtgaccgtag agcagttaga agtagctcgc actgacaaga
    66061 ccaaggtttt ggtgctgaat tcgccatcta atcccacagg tatgatttac acccgtgagg
    66121 aactcttggc aattggaaac tgggctgtag aaaatgatat tctcatccta gcagacgata
    66181 tctatggccg cttggtttat aatggtcatg agttcacacc gatttctagc ctatcggaag
    66241 cgattcgcaa gcaaacagtg gtcatcaatg gtgtgtctaa aacctatgcc atgactggtt
    66301 ggcggattgg ttatgccgtt ggagaagcag acattatcgc tgccatgtcc aagattgcag
    66361 gtcaaacaac ttcgaatccg tcagcagtag cccaatatgc agcagttgag gctctatcag
    66421 gtgagcaaga tactgtagaa agcatgcgtc aggcctttga ggaacgtctt aataccatct
    66481 atcccctcct tgcagaggtg ccaggatttg aagtggtcaa accgcaaggg gccttctatc
    66541 tcttcccaaa tgtcaaaaag gccatggaga tgaaaggcta cacggatgtg acagacttta
    66601 caactgctat cttagaagaa tccgaagtgg ccttggtaac aggagctgga tttggagcac
    66661 cagaaaatgt ccgcctcagc tatgcgacag acctagacac gcttaaagaa gcagtcgaac
    66721 gcttgaaagc atttatgggt agtgagaatg attgatcatt ttgagattaa ggtaaaggat
    66781 ttacaaattt cagaaggatt ttataggagt tttctcgctc ctttggacta taaattggct
    66841 tttaagacta gttctctaat tagttttcta tccccgaaca gccctcatcc tggtggtgat
    66901 ttttggctga ctcagggaac acaagatcct gttcattttg cttttttagc agaaaataag
    66961 gaagaagttt aggcttgtta tgaggctggc ttagaggcag gtgggcgaga caatggggct
    67021 cctggttatc gaagtgagcg tccgatttac tatgctgctt ttatgattga cctggatggg
    67081 aacaatatag aggtggtttg ccataaagaa taaaaaagaa aaggaaaaat aatgacaaaa
    67141 cgtgtaacga ttattgacgt aaaagactat gttggtcagg aagtgacgat tggcgcttgg
    67201 gttgccaata aatcaggaaa agggaaaatc gctttcttac aattgcgtga tggaacagcc
    67261 ttctttcaag gtgtggcttt taaaccaaac tttgtcgaaa aatttggtga agaagtggga
    67321 cttgagaagt ttgatgttat caaacgcttg agccaagaaa cgtctgttta tgtgacaggt
    67381 attgtcaaag aggacgaacg ttctaaattt ggctatgagt tggacatcac agacatcgaa
    67441 gtgatcggtg aatctcaaga ctacccaatc acaccaaaag aacacggaac agactttttg
    67501 atggataacc gtcacttgtg gctacgctct cgtaagcaag tagctgtgtt gcaaatccgt
    67561 aacgctatta tctatgcaac ttatgagttc tttgacaaga acggttttat gaagtttgac
    67621 agcccaattc tttcaggaaa tgcggcagaa gattctacag aactctttga aactgactac
    67681 ttcggaacgc cagcctactt gagccaatca ggtcaacttt acctagaagc aggggctatg
    67741 gctcttggtc gtgtctttga ctttggtcca gttttccgtg ctgaaaaatc aaaaacacgc
    67801 cgtcacttga ctgagttctg gatgatggat gctgagtact catacttgac acatgatgag
    67861 tcgcttgact tgcaagaagc ttatgtgaaa gctcttctac aaggtgttct tgaccgcgcg
    67921 cctcaagcct tggaaacctt ggaacgtgat acagaactct tgaaacgcta cattgcagag
    67981 ccattcaaac gtatcactta cgatcaagcc attgacctct tgcaagagca tgaaaatgat
    68041 gaagatgctg actacgagca tcttgagcat ggtgatgact ttgggtcacc acacgaaact
    68101 tggatttcaa accactttgg tgtgccaaca tttgtcatga actatccagc agccatcaag
    68161 gccttctaca tgaaaccagt tcctggaaat ccagagcgcg tgctttgtgc agacttgctt
    68221 gctccagaag gctatggaga aattatcggt gggtctatgc gtgaggaaga ttacgatgcc
    68281 cttgtcgcta agatggatga acttggcatg gatcgtacag aatatgaatt ctaccttgac
    68341 cttcgtaaat acggtacagt tccacacgga ggatttggta tcggtatcga acgtatggta
    68401 accttcgcag caggaacaaa acatatccgt gaagctattc cattcccacg tatgttgcac
    68461 cgtatcaaac cataagaaca ggaaaacgcc catgtggcgt tttttcgaat tctagtgttt
    68521 ttacttgcgt aaaaaaattt tttctagtat aatagtttat tgtgagcgaa cctcacttac
    68581 cccttgcaaa gtcttggggt cattagacca aaaggaggaa catatcaatg gctaaatacg
    68641 aaattcttta tatcattcgt ccaaacattg aagaagaagc taaaaacgct ttggtagcac
    68701 gttttgactc tattttgact gacaacggtg caactgttgt tgaatcaaaa acttgggaaa
    68761 aacgtcgtct tgcatacgaa atccaagatt tccgtgaagg actttaccac atcgttaacg
    68821 ttgaagcaaa tgacgatgca gctcttaaag agtttgaccg tctttcaaaa atcaacgctg
    68881 acattcttcg tcacatgatc gtcaaaattg acgcgtaaga aggtaaacta tgattaacaa
    68941 tgttgtactt gtagggcgta tgacacgtga cgctgagttg cgttataccc catcaaatgt
    69001 agcagttgcg acttttactc ttgcagtaaa ccgtacattt aagagtcaaa atggtgaacg
    69061 tgaggctgat tttatcaatg tcgttatgtg gcgccaacag gctgaaaatc ttgctaactg
    69121 ggctaaaaaa ggctcactta tcggggtgac aggtcgtatc cagactcgta gttacgataa
    69181 ccagcaagga caacgtgtct acgtgacaga ggtcgtggct gagaatttcc aaatgttgga
    69241 aagccgtagt gtgcgtgagg gtcacacagg tggagcttac tctgcaccaa ctgcaaacta
    69301 ttcagcacct acaaattcag taccagactt ttcacgtaat gaaaatccat ttggagcaac
    69361 aaacccattg gatatttcag atgatgattt accattctaa tggacaacta aacttataaa
    69421 ggagaaaaaa catggctcaa caacgtcgtg gcggattcaa acgccgtaaa aaagttgatt
    69481 acatcgcagc aaataaaatt gaatatgttg attacaaaga tactgagctt cttagccgtt
    69541 tcgtttcaga acgtgggaaa atccttcctc gtcgtgtaac aggaacttca gctaaaaacc
    69601 aacgtaaagt aacaacagct atcaaacgcg ctcgcgtaat ggctttgatg cctttcgtaa
    69661 acgaagatta aagaaaagac ccggttgggt ctctttttca tgagcttgaa aacaagaaag
    69721 cgaattaaga ccccaacggg tcttttttca caagctttga aatgagagag cgagttaggc
    69781 tcagtggctc cctttttacg agtttgaaaa caagagaaca cattacaagc acgatggagc
    69841 tttttcataa atatgtctct tttctcatcc aagaaattaa aataaaaatg ataaactttt
    69901 tgaaaatagg ggatttgcct actttatgat ataatggaaa gagttagatt gaaagaggta
    69961 gtgagatgga cgcgaaatta agatacaagg caaagaagat caagattgtc ttttttgata
    70021 ttgatgatac attgcggaat tcaaagacag ggtttattcc aactacaatt cccactgttt
    70081 ttaaacagtt gcgtgaaaaa ggaattttaa caggaatcgc ctctggacgt ggcatttttg
    70141 gtgttgttcc agagattcgt gatctcaagc ctgacttttt tgtaactttg aatggggctt
    70201 atatcgaaga taaaaaaggt caggtcattt atcagcatca gattggaaag tcagatgttg
    70261 aggagtatat ctcttgggct aagcaagaag gaattgagta tggcttggtt gggagtcatg
    70321 atgccaagtt gtcgactcgc accgatatga tgagtgaagc tatcaatcca atttatcccg
    70381 acttagatgt agatcccgat ttccatgaaa aagaagatat ctatcagatg tggacttttg
    70441 aagataaggg agatgacttg cacttgcctg acagtctctc agacaaactt cgcatggttc
    70501 gttggcatca acattcgtct gatattgtgc ctatttcagg ctccaaagcg acgggggtgg
    70561 aaaaggttgt ggaacacctt ggcttgaaac cagagaaggt catggttttt ggagatggtc
    70621 tcaatgactt ggaactcttt gattatgctg gaatcagcgt tgccatggga atttctcatg
    70681 ataaaatcaa agaaaaagca gattatatta caaaaacatt agaagaagat ggcatttttg
    70741 atgccttaga agtatttggt atggtagaaa aagaattgca ttttccacaa gtagacattg
    70801 aaacagtaga aggtcctctt gcgactatta agaccaatca cggagactta cgtatcaagc
    70861 ttttccctga acatgctcct aaaacagtgg ctaactttgt atctctttca aaagatggct
    70921 actatgatgg tgtcattttc caccgtatta tcaaggactt tatgatccaa ggtggagacc
    70981 caactggaac tggtatgggt ggcgagtcaa tctacggcga atcttttgag gatgaattct
    71041 cagaagagct ttacaatatc cgtggtgctc tttccatggc aaatgctggc ccaaatacca
    71101 acggcagcca gttctttatc gtgcaaaacc aacacctacc ttattctaag aaagaaatta
    71161 ctcgtggtgg ttggccagaa ccgattgcag aaatctatgc caatcaaggt gggacacctc
    71221 acctagaccg ccgtcacacg gtttttggtc agttagctga tgaagcatct tacgctgtct
    71281 tggatgccat tgctgctgtt gagacaggag ctatggacaa gccagttgaa gatgttgtaa
    71341 ttgaaactat tgaaatcgag gactaagatg aaaatcggtg ataagctaaa ggggcgtatt
    71401 acagggattc agccctacgg tgcctttgtt gagttagaga cgggtgatac ggggctgatt
    71461 cacatttcag aaattcggac aggatttatt gaaaatattc atgaaacctt gaaagtcgat
    71521 gaagaggttc aagttcaggt agtggattta gatgaattta cggggaaagc cagtctttct
    71581 atccgcactt tggaggaaga aaagtaccag tttcctagac ggagacgctt ttcaagcgac
    71641 cgctttaact acggttttgc tccctttcga cgaatgctac caatctggac tggagaagcc
    71701 ctgcactatt taaaaaagaa gaagtagttt agagttttat attttttgta atgttaatat
    71761 aaatttgcta taataggacc atggaagaag aacaattatt aaaatcagga gagcgcatta
    71821 accagctctt ttcgacagat atcaaaatca ttcaaaatag agaggttttt agctattcgg
    71881 tggatagtgt tctcttatca cgatttccac gttttcctaa gaaggggttg attgtagatt
    71941 tctgtgctgg gaatggagca gtggggcttt ttgctagcac tcgtactcaa gcacagatat
    72001 tgtctgttga gattcaggag cgtttggcgg atatggctga acgctctgtc cgtttgaatg
    72061 gattagagga gcaaatgcag gtcatctgcg atgatttgaa aaatatgcct gctcacattc
    72121 aggggagtaa ggtggatatg attttgtgta atccacccta tttcaaggtg gatcctcatt
    72181 ctaatctgaa cgagagtgaa cattatctct tggctcgaca cgaaatcacg actaatttgg
    72241 aagaaatctg tcatagtgcc cagagtattc tcaagtctaa tgggcgtttg gccatggttc
    72301 atcgtcctga tcgacttctg gatattttgg atacgttaaa acgacataat ctagccccta
    72361 agcgcctgca gtttgtttat ccaaaaagag aaaaggaagc caatatgctt ttgattgagg
    72421 cgatcaagga tggctcaaca agtggcttta aggtcttacc tcctttgatt gtccacaatg
    72481 atgatggctc ttatacgccc gaaatcgaag agatttatta tggatcataa ggcttatatg
    72541 tacgttctgg agtgtcgtga tggatcctac tatataggct atacgactga tgtgagaaga
    72601 cgcctcgcta tccacaatag tgggaaggga gccaaatata cacgagcacg cttgccagtc
    72661 aaacttatct atgctcaagg ttttgccagt aaggaagaag ccatgtcggc tgaagctctt
    72721 ctcaagcgta agaagaggcc acagaaggaa gaatttttat ctgaaaatca agatagaaat
    72781 ttactcagtt attttgaaga atcgtgggga gtcctttgac tcctcttacc tttgtcaaaa
    72841 agcgaaaaaa atgctacaat aaagaaaata aacaaaatga ggtattatca tgtccaagat
    72901 tctagtattt ggtcaccaaa atccagactc agatgccatc ggatcatctg tagcttttgc
    72961 ctaccttgca aaagaagctt acggtttgga tacggaagct gttgcccttg gaactccaaa
    73021 tgaagaaaca gcctttgtct tgaactattt tggtgtggaa gcaccacgtg ttatcacttc
    73081 tgccaaagca gagggggcag agcaagttat cttgactgac cacaatgaat tccaacaatc
    73141 tgtatcagat atcgctgaag tagaagttta cggtgttgta gaccaccacc gtgtggctaa
    73201 ctttgaaact gcaagcccac tttacatgcg tttggagcca gttggatcag cgtcttcaat
    73261 cgtttaccgt atgttcaaag aacatggtgt agctgtgcct aaagagattg caggtttgat
    73321 gctttcaggt ttgatttcag atacccttct tttgaaatca ccaacaacac acccaacaga
    73381 taaaatcatt gctcctgaat tggctgaatt ggctggtgtg aacttggaag aatatggttt
    73441 ggcaatgttg aaagctggta ccaacttggc tagcaaatct gctgaagaat tgattgacat
    73501 cgatgctaag acttttgaac tcaacggaaa taatgtccgt gttgcccaag tgaacacagt
    73561 tgacatcgct gaagttttgg aacgccaagc agaaattgaa gctgcaatgc aagctgccaa
    73621 cgaatcaaac ggctactctg actttgtctt gatgattaca gatatcgtca actcaaactc
    73681 agaaatcttg gctcttggtg ccaatatgga caaggtcgaa gcggctttca acttcaaact
    73741 tgaaaacaat catgccttcc ttgctggtgc cgtttcacgt aagaaacaag tggtacctca
    73801 attaactgaa agctttaatg cgtaagattt tgggtgtcag ctcaaaatcg gaaagtctag
    73861 tttgccttat atcgaaagga gtttcggctc ctttttttct aggagtgaag tatgttagaa
    73921 aatggcgatt tgatttttgt gagagatggg tcagacatgg gacaggccat ccagacttcc
    73981 acaggtaact atagccatgt tgccatttat ttggatggga tgatttatca tgctagtgga
    74041 caggctggtg ttgtctgtca agaaccggca gacttctttg agtccaatca tttatacgac
    74101 ctctatgttt acccagaaat ggatatccag tcggtgaagg aaagagcttg cagacatctt
    74161 ggagcaccct acaatgcttc tttctatcca gatgcagctg ctttctactg ctcccagtat
    74221 atagcagaaa tcctacctat ttttgaaact attcctatga aatttggaga tggggaacag
    74281 gagattagtg atttttggag ggagtattac atagaactag gtctgcctgt tcctctgaac
    74341 caagctggga ccaatcctag tcagttggca gcatcgcctc tgttacaatg taaagaaagg
    74401 gatcttcatg attcagattt ttaatccatc tcgtttgacg agacagccat ttttggagaa
    74461 ttgatccgct atctggacca gtatgaggat gtgattctac gggaaattaa gtctcagttt
    74521 ccagatgttg cagttgataa actcatggaa gagtatataa aggcaagctt gattctacgt
    74581 gaaaataagc gctattacct taattttcct acgcttgaat cacttgatag tcttgaactg
    74641 gatcaagaga tttttgtcag agaagctagt ccggtctatc aagccttgtt ggagcagagt
    74701 tttgagacgg aattgcgcaa tcaaatcaat gcagctattt tagttgaaaa gacggacttt
    74761 gcgcgcatta aaatgaccct gtccaattat ttttacaagg tcaaacagca gtatcctttg
    74821 acagaaaaac agcaggagct ctatgacatt ttaggagatg ttaatcctga gtatgccctc
    74881 aagtatatga cggctttttt gttgaaattt ctcaaaaaag accagcttat gcagaaatgc
    74941 cgtgatatct ttgtggacag tttggttgtc ttaggctata ttgtgcaaaa tgaagataga
    75001 aagtatgagt tggctatcga ttttgataag gagagattaa ctttctactt agcgtgattt
    75061 cttgtttctg agcacattgt ttgactttcc ttagtattcg gtataaacta tatgtaaccg
    75121 gtaacacata tcggaataaa ctaaaggaga caatcatatg tcacttgaaa acaaattgga
    75181 acaagcaaca ggcgctgtca aagaaggttt tggtaaagtt actggagaca gcaagacaga
    75241 acttgaagga gctgttgaaa aaacagttgc taaggcaaaa gacgttgtag aagacgcaaa
    75301 aggtgctgta gaaggtgccg ttgaaggttt gaaaaacgtt tttactaaat aataggaaaa
    75361 aatcaagggt ttcattttcc cttgattttt tctattctta taaataattt tctgcgacgg
    75421 ctgtatctcc tgggtaggat tctttcttgc cctggatgat ttggtaacaa tcggctccct
    75481 tacccgcaat aataactgca tctaattcgt gatttgtgat agccattgcc gccttgatgg
    75541 cttcttggcg atccgcaatc ttttcaacag gatgattgat gtagctacta atttcatctg
    75601 caatggccat tgggtcttca tagttagggt catcagcagt cagaaagact tgaatctcag
    75661 ggtgttgatt gaggaggagg ccaaagtcct tacgacgact ttctcccttg tttcctgttg
    75721 atcccagaac cagagcaatc tttccggttt gatgagtttc aaccacattg atgagttttt
    75781 tcagactatc cccattgtgg gcatagtcga tgaagacctt ggctccattt ttctgagtga
    75841 ggacttccat acgaccagga acgcgggttg cagcgatgcc ttttttgatg tcctcaagac
    75901 ttgctccgag acggagacaa gcaagtccag cagcaactgc attttcttgg ttgaagttgc
    75961 caatgagttg gatatcataa tctccagcga gtttacccgt agctgaaaag ctaaaggctt
    76021 tggaattctc gatttggtta tcaaattggc taccatagaa atcatggtct tgatcttcaa
    76081 cctgttcttt caagactgag aagtggtcca tgtcactgtt aatgatgact gctcggctat
    76141 tttccatcaa gagacgcttg tggtagaaat agtcttcaaa gctagggtgt tcaatcgggc
    76201 cgatatggtc aggagtgatg ttaagaaaga ctcctacatc aaaggtcagt ccatagactc
    76261 gatggactag ataggcttgg ctagagactt ccattacgag atggcttctt ccattcttaa
    76321 cagcttgagc catcatgtca aagaggtcga tattttcagg tgttgagaat gaagatttaa
    76381 agaaagttgt gccatccaaa gttgtattca tggttgataa gagggcggtt gggtaacgtt
    76441 gagataggat gttgtaagca aagtaagctg ctgttgtctt acccttagtt cctgtgaagg
    76501 cgagaatttt gagtttctct tgtggattac catagaactc catggcaatc aaactcatgg
    76561 ctttctttat atcgttcaca atgatgacag ggataccgac ttcgtagtcc ttttcagcta
    76621 cataccaagc taaaccttgt gttatagcag aaagaaggta ttctttttta aaggcagcac
    76681 cttttgcaaa aaaaagagtg tcttctgtta cttttcggct gtcgtagctg atgctatcaa
    76741 aaacaacttt gctgtagttg tagtggtaat gaccttggtc aataatttcg cgaaaaaggc
    76801 catctttctt taaaatatct aatacagttt caatttttat catactttct attgtaaacc
    76861 gaaagtcgca aatttacaag taacaaggaa aagtttataa tggaagataa ggagtttttc
    76921 ctagttatca aaattgaatg aggaatctat gtcgcacgaa aacaatcacc agcaggccca
    76981 gatgttacgg gggactgctt ggctaacggc tagtaacttt atcagtcgcc tactcggggc
    77041 tgtttacatt atcccttggt acatctggat gggggcttat gcagctaagg caaatggtct
    77101 ctttaccatg ggttacaata tctatgcttg gttcttgttg gtttcaacag cggggattcc
    77161 agttgcggtg gccaagcaag ttgccaagta taataccatg cgagaagaag agcatagctt
    77221 tgccctgatt cggagcttct taggctttat gacaggacta ggcctggttt ttgctttagt
    77281 cttgtatgtc tttgctcctt ggctagcaga cttgtctggc gtgggcaaag acttgatccc
    77341 aatcatgcaa agcttggctt ggggagtctt gattttcccg tctatgagtg ttatccgagg
    77401 atttttccaa gggatgaata acctcaaacc ttatgccatg agccaaattg ctgagcaggt
    77461 cattcgtgtt atctggatgc tcctagcaac ctttatcatt atgaagctcg gttcaggaga
    77521 ttatctagca gccgttaccc aatcaacctt tgctgccttt gtcggtatgg tagccagttt
    77581 tgcagtcttg atttatttcc ttgcccaaga aggttcactc aaaagagtct ttgaaacagg
    77641 agataagatt aacagtaagc gtctcttggt tgataccatt aaggaagcca ttccttttat
    77701 cctgacaggg tctgccatcc agctcttcca gattttggat cagctgacct ttatcaatag
    77761 tatgagctgg tttaccaact acagcaatga ggacttggtt gtcatgtttt cttatttctc
    77821 agccaatcct aataaaatca cgatgatttt gatttctgta ggggtttcga ttgggagtgt
    77881 tggtttgcca cttttgacgg aaaactatgt caagggggac ttgaaagcgg cttctcgtct
    77941 cgttcaggac agtctcaccc tactctttat gttcttgcta ccagcaacgg ttggagtggt
    78001 tatggtagga gaacctcttt atacggtctt ctatggtaag ccagatagtt tggctctggg
    78061 cttatttgtc tttgcagttt tgcagtctat tattttaggc ttgtacatgg tcttgtctcc
    78121 aatgcttcag gccatgttcc gcaaccgcaa ggccgttctc tattttatct atggttctat
    78181 tgccaagcta gtcttgcaac tacctaccat cgccctcttc cacagttatg gtcctttgat
    78241 ttcaacaacc attgctctca tcattcctaa cgtcttgatg tatcgggata tttgtaaagt
    78301 aactggtgtc aagcgcaagg tgattttgaa gcgaaccatt ttaatcagtt tgctgaccct
    78361 agtcatgttt ctgttaatag gaaccatcca gtggctgtta ggatttttct tccaaccaag
    78421 tggacgtttg tggagcttct tttatgtagc tcttgtcggt gccatggggg gtggacttta
    78481 tatggttatg agtctgcgta cctatttatt agataaggta ataggaaaag cccaagcaga
    78541 tcgcctgcga gcaaaattta agctttcgta aggtagcatt tataaataaa aggaataagt
    78601 tgaacaatct tttaggagaa cttgaaactt attccttttt tagcgtcaaa atagctaaaa
    78661 ttatctttca aaaatagaaa atgagttttt tgattttttg gaaaaaacaa ttgactaaac
    78721 aaaccaagag ttgtataata aaacaaatat ttaaagcagg aggttctgga aatgaaaaag
    78781 tctaagagca aatatctaac cttggcaggt tttgtcctgg gtacaggagt tttattgagc
    78841 gcgtgtggaa attctagcac tgcatcaaaa acctataact atgtttattc aagtgatcca
    78901 tctagtttga actatctagc agaaaaccgc gcaacaacca atgatattgt gaccaatctg
    78961 gtagatggtc tcatggaaaa tgaccaatat gggaactatg tgccatcctt ggcagaagat
    79021 tggactgttt ctcaggatgg tttgacctat acctacaaac ttcgtaagga tgccaagtgg
    79081 tttacttctg agggagaaga atatgcacct gtaactgccc aggattttgt gacaggattg
    79141 caatatgcag ctgataaaaa atcagaagcc ttgtatctag tgcaggactc tgttgcaggt
    79201 ttggatgact atatcactgg taaaacaagc gacttttcaa ctgtcggtat caaggctctt
    79261 gatgatcaaa ccgttcaata caccttggct cgaccagaac cttactggaa ctcaaaaaca
    79321 acctcaacca ttcttttccc agtcaatgca gatttcttga aatcaaaagg ggatgatttt
    79381 ggcaaggtag accctgctaa tattttgtac agtggacctt tcttgatgaa agcttttgtt
    79441 tcaaaatctg tcatcgaata caagaaaaat cctaactact gggatgctaa aaatgtcttt
    79501 gtagacgatg tgaaattgac ctactatgat ggtagtgacc aagatgctct tgttcgtaac
    79561 tttacagacg gagcctatag ctatgcccgt ctctatccga atagttcaag ttttgaaggg
    79621 attaaagaaa aatacaaaga tgatatcatc tacagtatgc aggatgctac gtcttattac
    79681 tggaatttta acctagatag acaagcttat aaatttactt ctaagacgac cgacattgaa
    79741 aagaaatcaa ctcaggaagc agttcttaat aaaaacttcc gtcaagctat taactttgcc
    79801 tatgatcgta cctcctatgg ggctcaaact cagggagaag acggagcgac taagattttg
    79861 cgtaacttgg ttgttcctcc aacctttgta agtatcaaag gaaaagattt tggtgaagta
    79921 gtagcctcta agatggtcaa taattatggt aaggaatggc aaggcatcaa ctttgcggat
    79981 ggtcaagacc cttactacaa tcctgagaaa gccaaggcta aatttgctga ggccaagaaa
    80041 gagctagaag ctaagggagt tcaattccct attcatttgg atgcgacagt tgaccaagct
    80101 tctaagaagg ggattcaaga agtaagctcc atgaagcaat ctattgaagc agctttaggt
    80161 acggagaacg tcgttattga tatccaacag ttatcaacag aggactatga taactcaagt
    80221 taccttgctc agactgctat tcagaaagac tacgaccttt acaatggtgg ttggagtcct
    80281 gactacttag atccatcaac ctatcttgat atctttagtg tcaagaatgg tggggttcta
    80341 caaaatcttg gactcgaccc tggtgaagcc aatgacaagg ctaaggcagt tggacttgac
    80401 acttatactc aaatgttgga agaggctaat aaggagcaag acccagccaa acgttatgag
    80461 aaatatgctg atattcaagc atggttgata gatagttctc tagcgattcc aaatgtttca
    80521 ttaggtggaa cgcctagctt gagaaaaaca gttcctttct cagcacctta ttcattggct
    80581 ggtaataaag gggttgaatc atataaatac ctcaaagtac aagataagat tgtcacaaca
    80641 gacgaatatg caaaagccag agaaaaatgg ttgaaagaaa aagaagaatc caataaaaaa
    80701 gcccaagaag aattggcaaa acatgtcaaa taaaatctaa ttgtagataa gtttgtgtaa
    80761 gaagtctttg tgcttaaaaa cgcataatat caggtatata aaatcctaga tgttatgcgt
    80821 tttgttatag gaagatttat tagattttat cctcaaattg agttattccc gactttatcc
    80881 gttgaaatat tataaggagt atttatgaaa ttaaaattat taagagtaga tactaaggtg
    80941 attatgtgga gtttcttact tgttctgtct agtctacttg ctttgttgct tccccttatc
    81001 ttaaagggtt taatagatgg gagttctatt gaaaatatag gttccaaagt atttcaatcg
    81061 tttttgattt ttattggtca agccttgttt tcttctattg gttactatct gtttagtcaa
    81121 tcgggtgaaa aaagatagca aaaatcagga aaaaagtgat agaggggttg atttatgcag
    81181 agaaatcctt ctttgataag agccaaagtg gggagttgac ttctgccatt gtcaatgaca
    81241 tgagtgtcat tcgtgagttt ttaattacga ctttcccaaa tattattctg agtttagtta
    81301 tggtacttgg ttccattgta gtcttattta gtcttgattg gaatctttct ctacttttat
    81361 tcatcactct tccttgtatg atgtttatta tcttgcccct ttccaatatc agtgaaaagt
    81421 atagtcgtcg tttacaggag gaaatcggat ttttaacagg gcaattgact gaaaagattc
    81481 aagaacatga attaattaag actaaccaag cagagaaaag tgtacaggat gttttggata
    81541 attgtattga aagggtacaa aacaattcac tgaaatcaga tagggttact tcttttgaga
    81601 ccccgtttgc tctcttattt atctttgcga ctatagttgt gatgctaacc tatgggggtt
    81661 atcgggtcag cgcaggatat atatctgtgg gaaccttggt ttcgtttttg atttacctct
    81721 ttcaattact taatcctatt agtaatatag ctaattttgt aactatttat tctagtagca
    81781 agggatcttc agttgcactg gagaacttgc ttgcagttcc taaagaaaaa tttgagggag
    81841 gaaaatcggt atcaggacaa gggttgaatt ttaaccatgt ctattttggt tatgatgaaa
    81901 atcgacctgt cttaaaggat attacttgtt caattttcaa ggggcaaaaa attgcttttg
    81961 ttggaccatc tggatcagga aaatcaacga ttgtgcgttt gttagagcgg ttttataaac
    82021 cgctttcagg agatattcta atggagcaat caagtatata tgattttaac ttaaaagaat
    82081 ggagaagtaa aatcgcttgg gtttcacaaa ataatgcagt cttatctggc agtattcgtg
    82141 acaatctttg tctcggtttg aatcgcttag taactgatga tgaattgatg aaagtgctag
    82201 acttagtatc actaggtgat gagattcgct ccatgaaaga gggactagat actgaagttg
    82261 gtgaacgcgg acgattcttg tcaggggggc aaagccaaag acttcaaata gctagaacct
    82321 acttaaaaga tgctgaaatt cttatatttg atgaagccac tgctaatctt gatgcggatt
    82381 ctgagtatgc gattatcagt agcctctatt ctgtattaaa ggagaagacg gttgtgatta
    82441 tagcgcatag tttgtcaacg gtaaaagatg tggattgtat tttcttctta gaggagggga
    82501 aaatcactgg ctcaggaact cataaggaac tactggaaaa tcatgagcgt tatgctcgtt
    82561 ttgtgcagga gcaaatgata gagtgaaggt gtcttttgag attcaccatt ttatagtcta
    82621 ttaaagggag caggaaaaac tcccttttta tatagtttga aactataact agctcttgaa
    82681 aagaagaaaa tgagttgatg aaaataagtg gtacaatagt tactatagat ttggaggtat
    82741 tgtatgagca aggaattaca cattaacaca attttggccc aggcgggtat taagtcagat
    82801 gaggcaacag gtgctttggt gacaccactt catttttcaa cgacctatca gcatccagag
    82861 tttggtcgat ctactgggtt tgactatacg cgcactaaaa atccaactcg tagtaaggct
    82921 gaggaagtct tggcggctat tgagtcagca gactatgccc tagcgactag ctcagggatg
    82981 tcagctattg tactggcctt tagcgtcttt ccagtaggaa gtaaggtctt ggcagtgcgt
    83041 gatctttacg gtggttcttt tcgctggttt aaccaagtgg agcaggaagg tcatttccat
    83101 tttacctatg ccaatacaga agaagagttg attgccgagt tagaaaagga tgtggatgtt
    83161 ctctatatcg aaaccccaac caatcccttg atgttggaat ttgatatcga aaaactagca
    83221 aaattggctc atgctaaggg tgccaaagtg gtggtggaca ataccttcta tagccctatc
    83281 taccaacgtc cgattgaaga tggagcagat atcgttctcc attcagcaac caagtatcta
    83341 gcaggccaca atgatgtctt ggctggagtg gttgtgacca atagtttaga actatacgag
    83401 aagctttttt acaatctcaa tacaacaggg gcagtcttgt ctccatttga cagctaccag
    83461 ttgcttcgtg gtctcaagac cttatctctt cgtatggagc gctcaacagc taacgcccaa
    83521 gaagtggttg cctttttgaa ggattctcca gcagttaagg aagttctcta cactggtcgt
    83581 ggaggcatga tttcctttaa agtagccgat gaaacacgca ttcctcatat tttgaacagt
    83641 ctcaaggtct tctcttttgc ggaaagtttg ggcggagtgg aaagtcttat tacttatcca
    83701 acgactcaaa ctcatgctga tattccagca gaagtacgcc attcttatgg tttgacagat
    83761 gacctcttgc gtttgtctat tgggattgag gatgctagag atttgattgc agatttgcgc
    83821 caagccttag aaggataaga caaagatggg aaaatatgat tttacaagcc tgcccaaccg
    83881 tttagggcac catacctata aatggaaaga aacagaaacg gatagtgaag ttctaccagc
    83941 ttggatagcg gatatggact ttgtggtctt gcctgaaatc cgccaagccg tgcaaactta
    84001 cgcagaccaa ctggtttatg gttataccta tgccagtgaa gacttaatta aggaagttca
    84061 aaagtgggaa gctacacaat acggttacaa ctttgacaaa gaggctcttg tctttatcga
    84121 gggtgtggta ccagccatct caacagctat tcaaaccttt acaaaagaag gcgaggcggt
    84181 tttaattaac acgcctgtct acccaccctt tgctcgcagt gtcaagttga ataatcgtag
    84241 attgattact aattccttag tggaaaagga tagtctgttt gagattgact ttgaccaact
    84301 tgaaaaggat ttggtggaag aggaggttaa actctatgtt ctttgcaacc ctcacaatcc
    84361 tggtggacgt gtttgggaaa aagaagtgtt ggagaagatt ggccaactct gccaaaaaca
    84421 cggtgttttg ttagtttcgg atgagattca ccaagatttg accctctttg gtcacaaaca
    84481 ccagtctttc aataccatca atcctgcctt caaaaatttt gctatcgtct tgagcagtgc
    84541 cactaaaaca tttaatattg ctggaacaaa aaattcctat gcagtcattg aaaatcctaa
    84601 gttgagactg gctttccaga aacgcctgtt ggccaataat cagcatgaaa tttcaggctt
    84661 gggttatttg gcgacagaag ctgcctatcg atacggtaaa gattggctag aggaactcaa
    84721 gcaagtcttt gaagaccaca tcaattatgt gatggatcta tttggaaaag agactaaaat
    84781 caaggtcatg aaaccgcaag gtacctactt gatttggctt gacttttcag cttatgacct
    84841 gactgatgaa acattgcaag agttgttgag aaatgaagcc aaggttatcc tcaaccgtgg
    84901 tttggatttt ggagaggaag gaagtctcca tgcccgcatc aatatagcta tgcccaaatc
    84961 tctgttgcaa gaagtctgtc agcggattgt ggctactttt gccaaacgtt aaaaatccag
    85021 ccttctagga gaaaagtctt cctagaaggc tattttcata ggcgaaaata tggtataata
    85081 aaaagataag gtaaaggtga aaatatggct aaattgattc cggggaaagt tcgtatcgaa
    85141 ggtgttgccc tttatgaaac tggtaaggtt gatatcatca aggaaaagaa caatcggctc
    85201 tacgctcgcg ttgcagaaga agaactgcgc tatagtttag aggatgattt ggttttttgt
    85261 gcctgtgatt tttttcaaaa gaggggttac tgtgtgcatt tggcagcgct agagcatttt
    85321 ctgaaaaatg atgagcgtgg tcaggaaatc ttgtggagtc tggaagaagg tcatgaagaa
    85381 aaagaggccg ttgaaaccaa ggtgaccttg ggtggcaagt ttttggatcg aattttatct
    85441 ccaaaatcag aatgcgccta tgagttatca gctgtgggtc aggtggaagc aggaaccaat
    85501 catatcttgt ggactctgag aatcggccaa atcaatagcc aaaaatacta tgtcattcgg
    85561 gatattccac tttttttaag gattgtcgag cagagaaagt cgtatatgat tggcaagatt
    85621 tatgaggagt ctctttcttg ggaagccttt gatgatgcca gccaagaact tttgactttc
    85681 ttgcacggac taacggagga agggctggtt tcagacctct ttttccaaaa ccaaggtcgg
    85741 cacctctttt tccctctgac cttttttgag cagggtgtga atttactgat ggccttgccc
    85801 cattttcaat ttgaccatca agtggatagc taccaaaccc tgctttttca ggatatgcat
    85861 gctgatgcca atctatttgc ctttacagta acagaatact cggactattt tgaaatggaa
    85921 atcagtgaga gtcctagggt caatgtcttt tatcagggag cagtactttt ccataaaggt
    85981 caggtttatt ttttaacaga ccagcagatg cgtcttctca aggaaattaa agcgttacct
    86041 gtgggtcaac aaggaaagaa atacctgcaa tttgatagca gtgatcgaga caaattggcc
    86101 tcctgtctga ctctttttat ccagatgggc accgtttcag ctccagaacg tctacaaatc
    86161 aaaacttttg cgccctcttt ttactttgac agggaagaag ataatcggat tcgtttggaa
    86221 attcagtttg attatggaaa tagacaggta tctagccgac aagagctaga agaattacca
    86281 ttttcaagtg acgcagactt agaagaaaga attttccaag tctgtttggc tgcgggcttt
    86341 gaagccgatt ttcaatcttg gcgtcaggcc ttaaaagcgg agtctgtcta tcattttttt
    86401 catgatatca ttccagtctt tgaaaaattc gggcatgttg acctatcaga taaactagaa
    86461 gagctttata gcctagcgag tcctcaggtg cagattgcct ccaagggagg tctcttggaa
    86521 atccagtttg attttcaaga tattgcccag gaggaaatcg accaagccat gcaggccttg
    86581 gttgccaatc aggattttta tattgattcg tctaatcaag tttacttttt cgatgaagaa
    86641 accaagaaaa ttcgccaaaa tctacaggaa ctggggcaat ttgaattaaa agatgggacc
    86701 ttgcaggctc ggaaatcctt ggcctacagt ttagctcatc tctttgaagg gcgagaccgt
    86761 gtttcttttt cacaagaatt ccagaatctg gcccaggatt tgacacatcc agaggacttt
    86821 cctcgacagg caactcaggt tcaggctgac ttgcgagatt atcaggaaaa gggaattggc
    86881 tggttgcaga tgctccatca ttatggtttt ggtgggattt tggctgatga tatgggactt
    86941 gggaaaaccc ttcagaccat tgcttttttg actagtcaag tgacaaaaga aagtcgggtt
    87001 ttgattctcg ctccgtcagg tttgatttac aactgggcag atgagtttca gaaatttgcc
    87061 ccacagttgg atgtggctgt tgttcatggt ttgaaagcaa gtcgtgagga gattcttgcc
    87121 gagagccatc aaatctatgt gactagctat gccaccttcc gtcaggacag tgagttttat
    87181 caggggatgg cctttgactt ccttttctta gatgaggctc aggtcatgaa aaatgcccag
    87241 accaagattg cccagacctt gagacaattt gtggtgccgt cggtctttgc cttgtcagga
    87301 actccgattg aaaaccatct gggtgagttg tggtctattt tccaaatcgt catgcccgga
    87361 cttttgccaa gcaagaaaga atttatgaaa ttgccagcag agcgagtggc tcagtttatc
    87421 aagcctttcg tgatgcgacg caagaaagaa gaagttctga ctgaattgcc agacttgatt
    87481 gaggtggttt ataaaaatga actggaagac cagcaaaagg ctatttacct tgcccagtta
    87541 caacagatgc gagaccatct ggctcaagtg tcagaacagg aatttcagcg aagtcgtgtg
    87601 gaaattttat ctggtttgat gcgcttgcgt caaatatgtg acactcctgc cctgtttatg
    87661 gaagattatc agggagccag cggcaaacta gatagtctcc gagacctact ggtacaggtg
    87721 gcagacggcg gacaccgtgt cttgattttc tctcagttca agggaatgtt ggaaaaaatt
    87781 gaacaagaac tgccagactt gggcctgaca tcctttaaaa ttacgggttc aaccccagcc
    87841 aaggaaagac aagacatgac caaggccttt aaccaaggag aaagagatgc ctttctgatt
    87901 tccctcaagg ctggtggggt cggtctgaac ctgacaggtg cagatacagt gatcttggtt
    87961 gacctttggt ggaatcctgc ggtggaagcg caagccattg gccgtgccca tcggatgggt
    88021 caggaagaaa cggttgaggt ctatcgcttg gtgaccaagg gaaccattga agaaaaaatt
    88081 caggaactcc aagaacaaaa gaaacatctg gtgtcacaag tattggatgg cacagagtca
    88141 cgtggtagtc tgaccctagc agaaattaga gaaattttgg gaatttctga agccagcact
    88201 tgaaaaatca agacaatacg ctataatgaa gtgttgaaag gaaatagaaa atgaaacaag
    88261 aacgatttcc attggtgtca gatgacgagg tcatgttgac tgaaatgcca gtcatgaatc
    88321 tctatgatga gtctgatctg atcagtaata tcaagggtga gtatcgagat aaaaattatt
    88381 tagaatgggc tcctattact gaagaaaaac cagtaaaacc gattgaaaag caagtcgaaa
    88441 aacctaaaaa ggctccttta ggggttaaaa aagaaggaaa gagctatgcg gaggtggcgc
    88501 gtgaagaagc gcgtgcggac ttgaaaaaga aacgctctgc taactaccta actcaggatt
    88561 tcagccttgc gagacgtcat tctcagccca gtctagttag acagggcaat caaccgacaa
    88621 ctcctttcca aaaggaaaat cctggtgaat ttgtcaaata tagccaaaaa ttgacccagt
    88681 ctcattatat cttggcggaa gaagttcatt ctatccctac caagaatgaa gaagtgtcag
    88741 cacctgctcc aaagaaaaac aattatgatt ttctaaagaa gagccaaatc tacaataaaa
    88801 aaagtaaaca aacagaacaa gaacgtcggg ttgcccaaga gttgaatctg accagaatga
    88861 cagaataggg gagaaaacat gtcaaagaca tatcatttta tcggaattaa gggatcaggg
    88921 atgagtgcct tggccttgat gttgcaccag atggggcaca aggttcaggg atcagatgtt
    88981 gaaaagtact actttaccca acgcggtctt gagcaggcag gaattaccat tcttcctttt
    89041 gatgaaaaga atctagacgg tgatatggaa attatcgctg gaaatgcctt tcgtccagat
    89101 aacaacgtcg aaattgccta tgcggaccaa aatggtatca gctacaaacg ttaccatgag
    89161 tttctaggta gctttatgcg tgactttgtt agcatgggag tagcaggagc acatggaaaa
    89221 acttcaacga caggtatgtt gtctcatgtc ttgtctcaca ttacagatac cagcttcttg
    89281 attggagatg ggacaggtcg tggttcggct aatgccaaat attttgtctt tgaatctgac
    89341 gaatatgagc gtcacttcat gccttaccac ccagaatact ctattatcac caacattgac
    89401 tttgaccatc cagattattt cacaagtctc gaggatgttt tcaatgcctt taacgactat
    89461 gccaaacaaa ttaccaaggg tctttttgtc tatggtgaag atgctgaatt gcgtaagatt
    89521 acgtctgatg caccaattta ttattatggt tttgaagctg aaggcaatga ctttgtagct
    89581 agtgatcttc ttcgttcaac aactggttca accttcaccg ttcatttccg tggacaaaac
    89641 ttggggcaat tccacattcc aacctttggt cgtcacaata tcatgaatgc gacagccgtt
    89701 attggtcttc tttacacagc aggatttgat ttgaacttgg tgcgtgagca cttgaaaaca
    89761 tttgccggtg ttaaacgtcg tttcactgag aaaattgtca atgatacagt gattattgat
    89821 gactttgccc atcatccaac agaaattatt gcgaccttgg atgcggctcg tcagaaatac
    89881 ccaagcaagg aaattgtagc agtctttcaa ccgcatacct ttacaagaac cattgccctg
    89941 ttggacgact ttgcccatgc tttaaaccaa gcagatgctg tttatctagc gcaaatttat
    90001 ggctcggctc gtgaagtaga tcatggtgac gttaaggtag aagacctagc caataaaatc
    90061 aacaaaaaac accaagtgat tactgttgaa aatgtttctc cactcctaga ccatgacaat
    90121 gctgtttatg tctttatggg agcaggagac atccaaacct atgaatactc atttgagcgt
    90181 ctcttgtcta acttgacaag caatgttcaa taggatgttc ccatggaaat tccaattaag
    90241 atcattcagg caagcaagtt tgatttgcct gagatagggg cacttcagac ctcgtctttt
    90301 ccagctgaaa agcagcaact ttcccatatt ttagaagaaa gtatccgtaa gtgtgcggat
    90361 acctttcttc tagctaggga tgaaaatcaa cttttaggct atattttatc aagtccccag
    90421 tcagacaatc cgcaatgtct aaaagtacat tctttagtca tcgagtctga ccatcagaga
    90481 cagggcctgg gaacacttct tcttgcagcc ttgaaagagg tggcagttga gctggattac
    90541 aaagggattc gtttggagag tcctgatgag ctgctttcct attttgaaat gaacggtttt
    90601 gttgatgaag aagaaacttt gctctatgca actagccagg gctatagtat gatttggttt
    90661 aatccctttt atctggagga acaatgaaaa tcagacaagc aagattagaa gatttggatc
    90721 ggattgttga acttgaattt gaaaattttt cggtcgaaga agccattcct ccttctgtct
    90781 ttgaagcaca tttgagagaa attcagacct cttttctggt tgctgaaaaa gaaggaagaa
    90841 tcatgggtta tatcgaagga ccagttggcc tgcaccgcca tctgcaagac cagtctttta
    90901 cagaagaaat aaaagactat agtcatgagc ctggtggtta tatctctgtg acctgtctgt
    90961 ctattgccaa ggaggcacag ggactcggac tgggtcagaa attgctgaca gccttgaaag
    91021 aagttgctct tgaagatgag agagatggca ttaatctaac ctgtcatgac tatctcatcg
    91081 cctattatga aaaacatgga tttgtcaacg aaggccagtc ccagtcaacc tttgcagggg
    91141 aaacatggta tgatatggtc tgggaaatga aaaaataagt taggaaaagt atcatagatt
    91201 gctttttttg gacttttaag atataatatt atggattatc aacaaggagg aaaaactttt
    91261 gagtgaaaag tcaagagaag aagagaaatt aagctttaaa gagcagattc tgagagattt
    91321 agaaaaagta aaaggctatg atgaagttct gaaagaagat gaggcagtag ttcgcactcc
    91381 tgcaaatgaa ccttcagctg aagaactcat ggctgattcc ttgtcaacgg tagaggagat
    91441 tatgagaaaa gctcctaccg tgcctactca cccaagtcaa ggtgtaccag cttctccagc
    91501 agatgagagt caaagagaaa ctcctggtgt tccaagtcat ccaagtcaag atgtaccttc
    91561 ttctccagcg gaagaaagtg gatcaagacc aggtccaggt cctgttagac ctaagaaact
    91621 tgaaagagaa tacaatgaaa ccccaacaag ggtagctgtt tcctatacga cggcagagaa
    91681 aaaagcagaa caagcaggtc cagaaacacc tacgcctgct acagaaatag tggatatcat
    91741 cagtgataca tcacgtcgta gccgtagaga aggagcaaaa cccgttaagc ctaagaaaga
    91801 gaagaagtca catgtgaaag cttttgtgat ttcattcctt gtattccttg ccttgctctc
    91861 agcaggtggt tacttcggtt accagtacgt gctagattct ttgttaccta tcgatgctaa
    91921 ttctaagaaa tatgtgacgg ttggaattcc agaaggttca aacgttcaag aaatcggtac
    91981 gacgcttgaa aaagctggtt tggtaaagca tggtctgatt tttagttttt atgccaagta
    92041 taaaaattat accgacttga aagcaggtta ctacaatttg caaaagagta tgagtacaga
    92101 agacttactc aaagagttgc aaaaaggtgg aacagatgaa ccgcaagaac ctgtacttgc
    92161 gactttgaca attccagaag gttatacctt ggataagatt gctcaagctg tgggtcaatt
    92221 gcaaggtgac ttcaaagagt ctttgacagc ggaggctttc ttggctaaag ttcaagatga
    92281 gacgtttatc agtcaagcag tagcgaaata tcctacttta ctggaaagtt tgcctgtaaa
    92341 agacagcggt gcgcgttatc gtttggaagg ataccttttc ccagctacat actctatcaa
    92401 ggaaagcaca actattgaga gcttgattga tgagatgtta gctgctatgg ataagaacct
    92461 atctccttac tatagtacta tcaaatctaa aaatttgact gtcaatgagt tgttgaccat
    92521 tgcttccttg gtcgaaaaag aaggtgccaa gacagaagat cgtaagctca ttgcaggtgt
    92581 attctacaat cgtttaaatc gtgatatgcc acttcaaagt aatattgcaa tcttgtatgc
    92641 ccaaggaaaa ctggggcaaa atatcagtct agctgaggat gttgcgattg ataccaacat
    92701 tgattcacct tataatgttt ataaaaatgt aggtctcatg cctggtccag tcgatagtcc
    92761 aagtctggat gcgattgagt caagcatcaa tcaaactaag agcgataacc tctactttgt
    92821 agcagatgtc acagaaggca aggtctacta tgctaacaat caagaagacc acgaccgcaa
    92881 tgtcgctgaa catgtcaaca gcaaattaaa ctaaacaaac taaaattatg tgatacgtca
    92941 cataattttc tttagaaaat attatcagaa gaaagttgag aaaaatggca gaaaaaacat
    93001 atcctatgac ccttgaggaa aaggaaaaac ttgaaaaaga attagaagaa ttgaaattgg
    93061 ttcgtcgacc agaagtggta gaacgcatta agattgcccg ttcatacggt gacctttcag
    93121 aaaacagtga gtacgaagca gctaaggatg aacaagcctt tgtcgaagga caaatctcta
    93181 gcttagaaac aaaaatccgc tatgctgaaa tcgtcaatag cgacgcagtt gcccaggacg
    93241 aagtagcgat tggtaaaaca gtcaccatcc aagaaattgg tgaggacgaa gaagaagttt
    93301 atattatcgt aggttcagct ggtgcggatg cctttgcagg taaggtttca aatgaaagcc
    93361 caattgggca ggccttgatt ggcaagaaaa caggtgacac agcaaccatt gaaacgcctg
    93421 ttggtagcta tgatgtaaaa atcttgaagg ttgaaaaaac agcctaaaaa cagaaaaagg
    93481 agtggggagg cgatgtgctt cactcactcc tttttccatt ttgctattct tcgaaaatct
    93541 cttcaaacca cgtcagcgtc gccttgccgt atgtatggtt actgactttg tcagtttcat
    93601 ctacaacctc aaaacagtgt tttgagcaac ctgcggctag tttcctagtt tgctctttga
    93661 ttttcattga gtattagatg tatagtgcat tgaagttaaa atagtaaact ttgatttcta
    93721 agacattatt agaaattaga ttaaattcct taatcgattt gcgcatgttt tatttcattt
    93781 cattatactt tagattggaa aataaggaat cacataaatc gcaagaaata gggaatctga
    93841 ttcgtgttta taaccgttca aaaagggaag aggctgaaag tgagccactt aatctttatg
    93901 tcgaagatga aaagggcaat ctccttgcgg gtttgatagc agagactttt ggaaattggc
    93961 tagaaatcga gtatttgttt gtaaaagagg aactgcgagg gcaaggaatc ggttcaaaac
    94021 tattgcaaca ggcagaaagt gaagctaaga atcgaaattg ttgttttgcc tttgtcaata
    94081 cttatcagtt ccaggcaccg gacttttatc agaaacatgg ctacaaggaa gttttttctt
    94141 tgcaagacta tctctacatt aggcaaagat attattacca aaagaatctg taaggtgagt
    94201 atggaggtat aatacaaaga gaggctcgca cataagtatg gaggtgtact gatgtatatg
    94261 agtaactatc gataaatacc agttataacc tagaaattgt gtctttctag acgatattga
    94321 ggacaatata atcgtagctc caaaattagg aatcaaggct tatcaggtta agaaaagaag
    94381 tgatgttgtt gatattttaa aacaatttat ttaaactaaa aactctctat ctttttaaat
    94441 tgacattaat ccgagattcc cctctaggat tttgtgttgc tttcattaaa tttacaggta
    94501 agacttgcta gcttcagtaa atatacacaa gtttttcaga atagagtgaa atccgaaaga
    94561 aaatggaaat aatgaaaact cttgtaggca taagaaaaca cctctgtgtt atacttgttg
    94621 ttcaaccaca aacacaagaa aggcacagaa atgcaagaca attatactac aaaagg
//
LOCUS       DAVHSY010000003        88019 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.003, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000003 DAVHSY010000000
VERSION     DAVHSY010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 88019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88019
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.003"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(343..768)
                     /locus_tag="VVR43_000223"
     CDS             complement(343..768)
                     /locus_tag="VVR43_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148643.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKV"
     gene            complement(897..1280)
                     /locus_tag="VVR43_000224"
     CDS             complement(897..1280)
                     /locus_tag="VVR43_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148644.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQFASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKETVLG"
     gene            complement(1302..1508)
                     /locus_tag="VVR43_000225"
     CDS             complement(1302..1508)
                     /locus_tag="VVR43_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148645.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(1495..1656)
                     /locus_tag="VVR43_000226"
     CDS             complement(1495..1656)
                     /locus_tag="VVR43_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6148646.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(2002..2958)
                     /gene="lytA"
                     /locus_tag="VVR43_000227"
     CDS             complement(2002..2958)
                     /gene="lytA"
                     /locus_tag="VVR43_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU6148647.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(3334..4704)
                     /locus_tag="VVR43_000228"
     CDS             complement(3334..4704)
                     /locus_tag="VVR43_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU6148648.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSTFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(5011..6177)
                     /gene="recA"
                     /locus_tag="VVR43_000229"
     CDS             complement(5011..6177)
                     /gene="recA"
                     /locus_tag="VVR43_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU6148649.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(6232..7488)
                     /locus_tag="VVR43_000230"
     CDS             complement(6232..7488)
                     /locus_tag="VVR43_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU6148650.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGNKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(7573..8589)
                     /locus_tag="VVR43_000231"
     CDS             complement(7573..8589)
                     /locus_tag="VVR43_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU6148651.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(8597..9115)
                     /locus_tag="VVR43_000232"
     CDS             complement(8597..9115)
                     /locus_tag="VVR43_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6148652.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLID"
     gene            complement(9105..9548)
                     /gene="tsaE"
                     /locus_tag="VVR43_000233"
     CDS             complement(9105..9548)
                     /gene="tsaE"
                     /locus_tag="VVR43_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU6148653.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(9634..10254)
                     /locus_tag="VVR43_000234"
     CDS             complement(9634..10254)
                     /locus_tag="VVR43_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148654.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(10560..11423)
                     /locus_tag="VVR43_000235"
     CDS             complement(10560..11423)
                     /locus_tag="VVR43_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6148655.1"
                     /translation="MNTLAEKFRLKRKELGLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDNLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLMELYQTKNFEHQEFLFGYIRVRYNYSHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDKEQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            12187..12501
                     /locus_tag="VVR43_000236"
     CDS             12187..12501
                     /locus_tag="VVR43_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6148656.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            12517..12903
                     /locus_tag="VVR43_000237"
     CDS             12517..12903
                     /locus_tag="VVR43_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6148657.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            12932..14317
                     /locus_tag="VVR43_000238"
     CDS             12932..14317
                     /locus_tag="VVR43_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU6148658.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVQAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            14320..14472
                     /locus_tag="VVR43_000239"
     CDS             14320..14472
                     /locus_tag="VVR43_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6148659.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            14495..15757
                     /locus_tag="VVR43_000240"
     CDS             14495..15757
                     /locus_tag="VVR43_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEU6148660.1"
                     /translation="MEGFLLNEQTWLQQLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLFEALERFNPDAPLEMLFDYVRIRFPTTDVQHVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDALVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKKGYLSTIPVDRYPKKRYNGR"
     gene            15702..15914
                     /locus_tag="VVR43_000241"
     CDS             15702..15914
                     /locus_tag="VVR43_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HEU6148661.1"
                     /translation="MCQPYQLTDIQKKDIMGDKTVRVRADLHHIIKIETAKNGGNVKE
                     VMEIRLRSKLKSVLIVHYLKILYNRN"
     gene            15963..16046
                     /locus_tag="VVR43_000242"
     CDS             15963..16046
                     /locus_tag="VVR43_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEU6148662.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            16171..16908
                     /gene="erm(B)"
                     /locus_tag="VVR43_000243"
     CDS             16171..16908
                     /gene="erm(B)"
                     /locus_tag="VVR43_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEU6148663.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            complement(17165..18412)
                     /locus_tag="VVR43_000244"
     CDS             complement(17165..18412)
                     /locus_tag="VVR43_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU6148664.1"
                     /translation="MSHNDSILNILGIKDKNIKIISVEEAEHNNDSVKEYITLITATL
                     SYPINRCRNCGFPTVNKDGFRKTHVRLASLNGRRYELELRKQRYKCKSCHTTFGAITN
                     LTKENQTLSSDLKNQIMLLARKGLSGQLIAEMCHCSPSSVRRTILERMEPHYRVAKLP
                     KHLCFDEFRSIKSVMSFICCDAETHQIVTKLQDRLSPTIVDYFESRYSKAERECVQSV
                     VIDLNAQYQSFIYRLFPNANIIIDRFHLVQLAGRALDNCRISILKQLDKQSQEYKIMK
                     SHWKLFHKKAEDLHPEEVVFLRGVKQYMTRQNAVDLITSKFSKFAEVYQTYQDITKAL
                     NERNSELLESTILDYQKTNTEMDTAIQTLRQNRKYVLNSAKFEYSNGPLEGINRKIKT
                     LKRTCYGFANQKFFFLRIDCIFS"
     gene            18592..18813
                     /locus_tag="VVR43_000245"
     CDS             18592..18813
                     /locus_tag="VVR43_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148665.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            18930..19427
                     /locus_tag="VVR43_000246"
     CDS             18930..19427
                     /locus_tag="VVR43_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEU6148666.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            19402..19908
                     /locus_tag="VVR43_000247"
     CDS             19402..19908
                     /locus_tag="VVR43_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6148667.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            19892..22339
                     /locus_tag="VVR43_000248"
     CDS             19892..22339
                     /locus_tag="VVR43_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6148668.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            22342..24519
                     /locus_tag="VVR43_000249"
     CDS             22342..24519
                     /locus_tag="VVR43_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU6148669.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKAERASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            24516..25517
                     /locus_tag="VVR43_000250"
     CDS             24516..25517
                     /locus_tag="VVR43_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEU6148670.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            25514..26446
                     /locus_tag="VVR43_000251"
     CDS             25514..26446
                     /locus_tag="VVR43_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6148671.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            26691..26807
                     /locus_tag="VVR43_000252"
     CDS             26691..26807
                     /locus_tag="VVR43_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEU6148672.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            26823..28742
                     /gene="tet(M)"
                     /locus_tag="VVR43_000253"
     CDS             26823..28742
                     /gene="tet(M)"
                     /locus_tag="VVR43_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEU6148673.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            29106..29351
                     /locus_tag="VVR43_000254"
     CDS             29106..29351
                     /locus_tag="VVR43_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148674.1"
                     /translation="MRQIGVSYSGFVDESYTLLSLFDDVEQIEKDNRLQTAIDVVREQ
                     FGFLAIQKGTVLTEGSRNIERSKLIGGHSAGGLEGLK"
     gene            29348..29683
                     /locus_tag="VVR43_000255"
     CDS             29348..29683
                     /locus_tag="VVR43_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imsC-like protein"
                     /protein_id="HEU6148675.1"
                     /translation="MKQEKNTVQFSEIRSKGCNDIEMLERFLHGIVETATSKLRQRKL
                     KTTEISIRLVHAKSENRLPLEFTFSIKPTSSSVIIYTEVINRFKECYTGGGIQGFTIQ
                     FDKNTLASA"
     gene            29696..30064
                     /locus_tag="VVR43_000256"
     CDS             29696..30064
                     /locus_tag="VVR43_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148676.1"
                     /translation="MIDRSYLPFQSAREYQDTKMQKWMGFFLSEHASALSDDTNKVTY
                     MSDLSLEKKLLLLSQVYAGQLRTRIQVIEKNKRVSYTGTIPSLTKDFILIKTTTGHIN
                     LKLKDIISIELVEEVLYESA"
     gene            30051..30350
                     /locus_tag="VVR43_000257"
     CDS             30051..30350
                     /locus_tag="VVR43_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148677.1"
                     /translation="MNQLEFQRNHLQMDYYSESYQDFERDFYRYSNMNIPLTFLTDDI
                     LKTMATSRKNYFVLNKEKSRDNRDHFFIFEVSTVDENPLIYHYTYKKTTIYLAEK"
     gene            complement(30468..31931)
                     /gene="msr(D)"
                     /locus_tag="VVR43_000258"
     CDS             complement(30468..31931)
                     /gene="msr(D)"
                     /locus_tag="VVR43_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(D)"
                     /protein_id="HEU6148678.1"
                     /translation="MELILKAKDIRVEFKGRDVLDINELEVYDYDRIGLVGANGAGKS
                     TLLRVLLGELTPPGCKMNRLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLNIQTMSG
                     GEETRLKIAQALSAQVHGILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLD
                     EIVDKIWELKDGKITEYWGNYSDYLRQKEEERKSQAAEYEQFIAERARLERAAEEKRK
                     QARKIEQKAKGSSKKKSTEDGGRLAHQKSIGSKEKKMYNAAKTLEHRIAALGKVEAPE
                     GIRRIRFRQSKALELHNPYPIVGAEINKVFGDKALFENASFQIPLGAKVALTGGNGIG
                     KTTLIQMILNHEEGISISPKAKIGYFAQNGYKYNSNQNVMEFMQKDCDYNISEIRSVL
                     ASMGFKQNDIGKSLSVLSGGEIIKLLLAKMLMGRYNILIMDEPSNFLDIPSLEALEIL
                     MKEYTGTIVFITHDKRLLENVADVVYEIRDKKINLKH"
     gene            complement(32051..33268)
                     /gene="mef(A)"
                     /locus_tag="VVR43_000259"
     CDS             complement(32051..33268)
                     /gene="mef(A)"
                     /locus_tag="VVR43_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012102963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(A)"
                     /protein_id="HEU6148679.1"
                     /translation="MEKYNNWKRKFYAIWAGQAVSLITSAILQMAIIFYLTEKTGSAM
                     VLSMASLVGFLPYAILGPAIGVLVDRHDRKKIMIGADLIIAAAGAVLAIVAFCMELPV
                     WMIMIVLFIRSIGTAFHTPALNAVTPLLVPEEQLTKCAGYSQSLQSISYIVSPAVAAL
                     LYSVWDLNAIIAIDVLGAVIASITVAIVRIPKLGNQVQSLEPNFIREMKEGVVVLRQN
                     KGLFALLLLGTLYTFVYMPINALFPLISMEHFNGTPVHISITEISFAFGMLAGGLLLG
                     RLGGFEKHVLLITSSFFIMGTSLAVSGILPPNGFVIFVVCCAIMGLSVPFYSGVQTAL
                     FQEKIKPEYLGRVFSLIGSIMSLAMPIGLILSGFFADKIGVNHWFLLSGILIIGIAIV
                     CQMITEVRKLDLK"
     gene            complement(33654..33824)
                     /locus_tag="VVR43_000260"
     CDS             complement(33654..33824)
                     /locus_tag="VVR43_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HEU6148680.1"
                     /translation="MKYFEVELENPDEFLKLQTEDFVKANRLLLRKIIQSVTVYEENF
                     VISFKSGIELEV"
     gene            34346..34537
                     /locus_tag="VVR43_000261"
     CDS             34346..34537
                     /locus_tag="VVR43_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEU6148681.1"
                     /translation="MTSKLTASTCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIE
                     IKQFKVTVITEPDAKTQSR"
     gene            complement(34597..34950)
                     /locus_tag="VVR43_000262"
     CDS             complement(34597..34950)
                     /locus_tag="VVR43_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6148682.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            35455..35877
                     /locus_tag="VVR43_000263"
     CDS             35455..35877
                     /locus_tag="VVR43_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU6148683.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            35874..36104
                     /locus_tag="VVR43_000264"
     CDS             35874..36104
                     /locus_tag="VVR43_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6148684.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            36565..36768
                     /locus_tag="VVR43_000265"
     CDS             36565..36768
                     /locus_tag="VVR43_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEU6148685.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            36850..38067
                     /locus_tag="VVR43_000266"
     CDS             36850..38067
                     /locus_tag="VVR43_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6148686.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            38958..40973
                     /locus_tag="VVR43_000267"
     CDS             38958..40973
                     /locus_tag="VVR43_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6148687.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTPVFSYTTFGNGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGNLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFGALTLISQISQLRSSGIRLISGEKRWFIFLRPVGEDLKGIAVGFSLAGVLTI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNFITSTEWYDY
                     SPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEDHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            40975..41607
                     /locus_tag="VVR43_000268"
     CDS             40975..41607
                     /locus_tag="VVR43_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6148688.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLTG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(42535..42948)
                     /gene="ndk"
                     /locus_tag="VVR43_000269"
     CDS             complement(42535..42948)
                     /gene="ndk"
                     /locus_tag="VVR43_000269"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU6148689.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(43059..46736)
                     /gene="rpoC"
                     /locus_tag="VVR43_000270"
     CDS             complement(43059..46736)
                     /gene="rpoC"
                     /locus_tag="VVR43_000270"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU6148690.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(46769..50380)
                     /gene="rpoB"
                     /locus_tag="VVR43_000271"
     CDS             complement(46769..50380)
                     /gene="rpoB"
                     /locus_tag="VVR43_000271"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU6148691.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            50796..50866
                     /locus_tag="VVR43_000272"
     tRNA            50796..50866
                     /locus_tag="VVR43_000272"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:50828..50830,aa:Cys,seq:gca)
     gene            complement(51064..52395)
                     /locus_tag="VVR43_000273"
     CDS             complement(51064..52395)
                     /locus_tag="VVR43_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU6148692.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(52686..53510)
                     /gene="endA"
                     /locus_tag="VVR43_000274"
     CDS             complement(52686..53510)
                     /gene="endA"
                     /locus_tag="VVR43_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU6148693.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSNATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(53549..53737)
                     /locus_tag="VVR43_000275"
     CDS             complement(53549..53737)
                     /locus_tag="VVR43_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU6148694.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(53730..55013)
                     /gene="murA"
                     /locus_tag="VVR43_000276"
     CDS             complement(53730..55013)
                     /gene="murA"
                     /locus_tag="VVR43_000276"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU6148695.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(55037..55267)
                     /locus_tag="VVR43_000277"
     CDS             complement(55037..55267)
                     /locus_tag="VVR43_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU6148696.1"
                     /translation="MIQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(55325..56362)
                     /locus_tag="VVR43_000278"
     CDS             complement(55325..56362)
                     /locus_tag="VVR43_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU6148697.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(56346..56834)
                     /gene="coaD"
                     /locus_tag="VVR43_000279"
     CDS             complement(56346..56834)
                     /gene="coaD"
                     /locus_tag="VVR43_000279"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU6148698.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDMIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(56824..57363)
                     /gene="rsmD"
                     /locus_tag="VVR43_000280"
     CDS             complement(56824..57363)
                     /gene="rsmD"
                     /locus_tag="VVR43_000280"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU6148699.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(57428..58420)
                     /locus_tag="VVR43_000281"
     CDS             complement(57428..58420)
                     /locus_tag="VVR43_000281"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU6148700.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(58532..59215)
                     /locus_tag="VVR43_000282"
     CDS             complement(58532..59215)
                     /locus_tag="VVR43_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU6148701.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(59271..60011)
                     /locus_tag="VVR43_000283"
     CDS             complement(59271..60011)
                     /locus_tag="VVR43_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU6148702.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            60045..60323
                     /locus_tag="VVR43_000284"
     CDS             60045..60323
                     /locus_tag="VVR43_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU6148703.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            60401..61327
                     /gene="yidC"
                     /locus_tag="VVR43_000285"
     CDS             60401..61327
                     /gene="yidC"
                     /locus_tag="VVR43_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU6148704.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(61402..62196)
                     /gene="pflA"
                     /locus_tag="VVR43_000286"
     CDS             complement(61402..62196)
                     /gene="pflA"
                     /locus_tag="VVR43_000286"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU6148705.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(62322..63572)
                     /locus_tag="VVR43_000287"
     CDS             complement(62322..63572)
                     /locus_tag="VVR43_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU6148706.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPEEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(63639..64466)
                     /gene="purR"
                     /locus_tag="VVR43_000288"
     CDS             complement(63639..64466)
                     /gene="purR"
                     /locus_tag="VVR43_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU6148707.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(64733..65674)
                     /locus_tag="VVR43_000289"
     CDS             complement(64733..65674)
                     /locus_tag="VVR43_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU6148708.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(65664..66920)
                     /locus_tag="VVR43_000290"
     CDS             complement(65664..66920)
                     /locus_tag="VVR43_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU6148709.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDNLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(66922..67584)
                     /locus_tag="VVR43_000291"
     CDS             complement(66922..67584)
                     /locus_tag="VVR43_000291"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU6148710.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTAEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(67547..68203)
                     /locus_tag="VVR43_000292"
     CDS             complement(67547..68203)
                     /locus_tag="VVR43_000292"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU6148711.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRQEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(68214..69092)
                     /gene="rsgA"
                     /locus_tag="VVR43_000293"
     CDS             complement(68214..69092)
                     /gene="rsgA"
                     /locus_tag="VVR43_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU6148712.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(69094..69966)
                     /gene="rsmA"
                     /locus_tag="VVR43_000294"
     CDS             complement(69094..69966)
                     /gene="rsmA"
                     /locus_tag="VVR43_000294"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU6148713.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(70352..70510)
                     /locus_tag="VVR43_000295"
     CDS             complement(70352..70510)
                     /locus_tag="VVR43_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148714.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEG"
     gene            complement(70503..71144)
                     /locus_tag="VVR43_000296"
     CDS             complement(70503..71144)
                     /locus_tag="VVR43_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6148715.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(71146..73176)
                     /locus_tag="VVR43_000297"
     CDS             complement(71146..73176)
                     /locus_tag="VVR43_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6148716.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEVLSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQFICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGLSATALLPNYREMQEMEKASDKWSQSSDRYRLSFGW
                     SSAFADEEGMRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGVEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(73444..74343)
                     /locus_tag="VVR43_000298"
     CDS             complement(73444..74343)
                     /locus_tag="VVR43_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6148717.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEELMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(74415..74975)
                     /gene="rnmV"
                     /locus_tag="VVR43_000299"
     CDS             complement(74415..74975)
                     /gene="rnmV"
                     /locus_tag="VVR43_000299"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU6148718.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(74975..75748)
                     /locus_tag="VVR43_000300"
     CDS             complement(74975..75748)
                     /locus_tag="VVR43_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU6148719.1"
                     /translation="MIFDTHTHLNVEEFAGRETEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(76053..76946)
                     /locus_tag="VVR43_000301"
     CDS             complement(76053..76946)
                     /locus_tag="VVR43_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU6148720.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLETTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKNKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(77230..77364)
                     /gene="rpmH"
                     /locus_tag="VVR43_000302"
     CDS             complement(77230..77364)
                     /gene="rpmH"
                     /locus_tag="VVR43_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU6148721.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(77509..78723)
                     /locus_tag="VVR43_000303"
     CDS             complement(77509..78723)
                     /locus_tag="VVR43_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6148722.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSNSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLASDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(78879..79171)
                     /locus_tag="VVR43_000304"
                     /pseudo
     CDS             complement(78879..79171)
                     /locus_tag="VVR43_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            79333..79785
                     /locus_tag="VVR43_000305"
     CDS             79333..79785
                     /locus_tag="VVR43_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU6148723.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(79820..81208)
                     /locus_tag="VVR43_000306"
     CDS             complement(79820..81208)
                     /locus_tag="VVR43_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6148724.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQTLDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            81274..82236
                     /locus_tag="VVR43_000307"
     CDS             81274..82236
                     /locus_tag="VVR43_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU6148725.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVNTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(82265..82513)
                     /locus_tag="VVR43_000308"
     CDS             complement(82265..82513)
                     /locus_tag="VVR43_000308"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148726.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     SKHVFEVVDRTDEVSSKHVFEVVDRTDEVSNHTYGKAT"
     gene            complement(82577..83587)
                     /gene="ccpA"
                     /locus_tag="VVR43_000309"
     CDS             complement(82577..83587)
                     /gene="ccpA"
                     /locus_tag="VVR43_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU6148727.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(84012..84611)
                     /locus_tag="VVR43_000310"
     CDS             complement(84012..84611)
                     /locus_tag="VVR43_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6148728.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSVADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(84613..85710)
                     /locus_tag="VVR43_000311"
     CDS             complement(84613..85710)
                     /locus_tag="VVR43_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6148729.1"
                     /translation="MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGIMLVYVAGNTAFVAGNYIWFFFFLSNILIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKIDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTIR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(85710..86447)
                     /locus_tag="VVR43_000312"
     CDS             complement(85710..86447)
                     /locus_tag="VVR43_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6148730.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GEPANFMRDYLISMTAFSMMSTTIFSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(86449..87333)
                     /locus_tag="VVR43_000313"
     CDS             complement(86449..87333)
                     /locus_tag="VVR43_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6148731.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(87320..87514)
                     /locus_tag="VVR43_000314"
     CDS             complement(87320..87514)
                     /locus_tag="VVR43_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148732.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFICGALGFGFM
                     IFVVFPMGMEWLKGESHDCG"
     gene            complement(87511..87717)
                     /locus_tag="VVR43_000315"
     CDS             complement(87511..87717)
                     /locus_tag="VVR43_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148733.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        26585 a        18734 c        16591 g        26109 t
ORIGIN      
        1 tgataaaata accaaaaact actcgctatc ccctctcaca ttaccctaca tatcgtttga
       61 catgcgactg atagttcagg aaaacttcaa ggagaacttt tctctcatcc actatgcagg
      121 acttactatt tcacttctac tcctataggc tcaatttgac acttttcttt ttcgaattgc
      181 tcatatgcct cctgaatagt gagttcgatt tatccaaatt tatttttgtc tattttgatg
      241 aatacttcca cgaagatagt ctgaaaatga atttgcacca attttccttc tctttttaag
      301 catattattc cagatatgat tgccctcttg ttcagtaata aattacactt taaacgcttc
      361 aatcagtata tctcctgttg tcatatgttc taaagaaaat tcttctacat atgatttaac
      421 atctcttagg ttattacttc ctaatatccc attatgcttt ttcgctaagg aaatagaagc
      481 cgcttctccc ttaccaataa tcttgttact atcatgattt cttgttaaat ctctatataa
      541 tgcgtattct tcagttccaa tgtctatgct cacaatctca gctgaaccct tagctaccaa
      601 ctggtctatc ctagatttta aatggggaat tgtaggtata ttgatttcat catacacctc
      661 ttgtggaata acaattttac ccgaatagag cttttctaaa agatgttcag tgccaaccca
      721 taaaaatact gaaatacaat ctgcatcaat aaatacacga ctagtcaaac gacaactccc
      781 tcctcttcat atagcccata tacaatatca tatctgaaag catctagtaa cagttcctca
      841 tacttccctt gcgaaattct gttattttct aaaagttgtt cagtcgaatt aatatattat
      901 cctaataccg tttccttttt actttctgac aaaggacgat ataaacttgt atcatagcct
      961 aatcttgaag ctgtctctat aacactaata tccatatttt taatttcttc tgcatcaagg
     1021 tatccatcat ttctcaatct atataacata gctttatgac tgataccata aaactgaccc
     1081 aattttataa tatcttctac ttcaagatga gttctattgg cattttctct aatttcctca
     1141 accatcctat acagtgaaga tgggaaaatt aaaaaataag aagcaaactg atccgctttt
     1201 ctttcagttt catctccttc accaatcaag ataagactga ctgaactctt cttcacctca
     1261 tcataataaa gatgatacag ttcatgtgct aaagaaaatc tttaccttcc taatgacatg
     1321 tctgaattga ctgcaatgag actgaactga gttcctttat aacagactcc gctaatattc
     1381 tttccgagtc cataaaatac cagcgtcaaa ttttctatct tttgtaccaa tttaaaaata
     1441 tctatcggcg attcaccatc agctcccaac ttttttctaa gatttggagc tttattactt
     1501 aaatccattc gtgatattcc tttcaccttt ttccattttg gcaatcatgc tttgattcaa
     1561 agacaaatac tcagcaatct tatcttgagt aagatttgaa gatattctaa gttcttttat
     1621 tctttttcca acatcacata catttatcat attcatacac ctctcataaa aagaatagca
     1681 cactcttgtc ataatttttt aaataaaaaa attatgacaa aacaaggaag caatttattg
     1741 atgctgctta aaaatctaaa attgatgagt tcctatcaaa aatcgtatct tcaacctcaa
     1801 aacagtactt aaagctatcc gactcggttt acattgtcaa atttagattt tatttgagca
     1861 taactttcta gtttgctttc tgatttttgt ttaatatagt agcaaacatt gaaggaaata
     1921 tctccacaaa aaaacgcata ctattaagct ttttcaagac ctaataatat gcgctgttct
     1981 gatttgaaag acattccatt attattttac tgtaatcaag ccatctggct ctactgtgaa
     2041 ttctggcttg tctgccagtg ttccgtctgg tttgaggtag taccagcctg ttccgtccgc
     2101 tgactggata aaggcatttg ataccatggc gccttcttta gcgtctaagt agtaccaagt
     2161 gtccttgtac ttgacccagc ctgtcttcat ggcaccttct tcgttgaaat agtaccactt
     2221 atcagcgatt ttcttccagc ctgtagccat ttcgcctgag ttgtcgaacc agtaccagtt
     2281 gccgtctgtg tgcttcctcc agcggtctgc aagcatatag cctgaactgt caaagtagta
     2341 ccaagtgcca ttgattttct caaacttgtc ttttggataa gagccgtctg aatgtacgta
     2401 ccagtagcca gtgtcattct tctgccagcc tgtttcaatc gtcaagccgt tctcaatatc
     2461 atacttaaac tgctcacggc taatgcccca ttttgccaag taagggtatg gatccacatg
     2521 gtctgagtgg ttgtttggtt ggttattcgt gcaatactcg tgcgttttaa ttccagctaa
     2581 actccctgta tcaagcgttt tcggcaaacc tgcttcatct gctagattgc gtaagagttc
     2641 gatataaagg cggtagtccg tcatgaactc ttctttagtt gaatggcttt caatcagttc
     2701 aaccgctgca taggtctcag cattccaacc gcccccaacg tcccaggcac cattatcaac
     2761 aggtcctacc tgcatgatgc aaccgttccc aacaatgtgc gagaaaaaac ctaattctgg
     2821 gtctttccgc cagtgataat ccgcttcatt ctgtacggtt gaatgcggat tcccagttga
     2881 gtgtgcgtgt acttgcctat atggttgcac gccgacttga ggcaaatctg ttcttaattt
     2941 actcacatta atttccatat tctactcctt atcaattaaa acaactcatt ttttacaatc
     3001 cagaaccaga aactccttta tttctacctt acaaagaaga caatcttagt cacgattagg
     3061 cttgtagata gaacttcaaa acgcactatt ttgacactgt aaataggact gacaaggtct
     3121 gcattctatc tacaataaca ccccagacta aaaagctttt caaaagtata tttttacagt
     3181 ctctatatgt ccttttcata aatactatac tttattatat catataaaag aagtcaaaag
     3241 tctgttaaac tattttcaac accaaactaa agacgagaac acaagttttt tcgattttca
     3301 ctagaggaaa tggattttat tcagtaaatc caactaggat tgcactttgg ttgccaagat
     3361 tgccttgcct tcttttatca agggatgacg gaataatgag aagtacagtt gaactgtcat
     3421 ggcaacccag ataagaggtt cacaaaggat aacaccctta tatcctgccc aaggaataat
     3481 caaaaccaca aaaacgattt ttccgattag ttcaataaag ctagaaacta gaggaaggat
     3541 cttttgcccc aagccctgca agcaattgcg ataaatcaac aagaggctca aaatgggata
     3601 aaaggttgaa ctgatttgca gatagagact tccattttct atcaagtaac catctgtcga
     3661 actagccaag aaggaaacca aagctggact ggcaaaaaag aggaaaatac aaacaaaaac
     3721 tgcccaggat atacttaaac gactgccgat tcgaagacct tgaacaatac ggtcaggtcg
     3781 cttagctcct agattctgag aagcaaaggt cgtcattgat gcagaaatag cggtcatagg
     3841 aagaagggca aaggtcataa tgcgtcgagc tgccgtctgg gcactaataa tcactgcacc
     3901 aaatgtatta acagaaaact gtaaaatcac actgccgata gatacaattg aactcatcaa
     3961 gcccatagcc aaaccttgct ccaagagatc cgcgtacaag cttttgtccc atttgaaatg
     4021 tttaaactgt ggcaagagtt ctggcacact tttacgaata taataaaagc agagaaccgc
     4081 tgataaacct tgcgaaataa tggtagcaag tcctgcggat tgaactccca gatgcaattg
     4141 cgtaataaaa tagagatcca gaaccacatt aaccaaggca gagaaaatca gaaatcccag
     4201 ggctgctaga ctgtcaccaa tagaccgcaa caagcctgca aaaagattat aagcaaagct
     4261 gacacctaca caggtcacaa tcatagaaat atattgataa gattgaggaa gaatttctgc
     4321 aggagtatct aagtattgca agagaggata caagccaaga aagcccagca acataactag
     4381 aatgctcaaa agagcaccta aaatccaggt ggctgctact gcttccttga ttttagtgaa
     4441 attccgagcc ccataataac gagcaatgac aatccccatg ccattgccaa caccaagtgt
     4501 aaagcctaca atcaggtcaa aaatcgctgt cgtcgctcct actgcagcca aggattcttg
     4561 accaagaaat cgtccaacaa tcaagacatc agcagtgtta tagagctgtt gaaaaatatt
     4621 tgatagcaag attggaaagg tgaagcttaa gagcgaggga agaatcggac catgtatcag
     4681 gtccactgtt cgttttttat tcataaagct attatatcag ctttccagag gagcgacaag
     4741 aaacagcaaa cttatatata gcggaatgaa ataaggacag tcaaatcgat ttttaacaat
     4801 gttttagaag tagatgtgta ctattctagt ttcgatctat tatagttggt tgagtttgga
     4861 atagtacgct gtagctgcta aaacatttct agaaattaat ttgactttcc taataaagtt
     4921 gttcatatct tatttcaagc tactatatat aatctaaaaa cttgaatcaa aaatcgaaaa
     4981 agtagcggat ttctccactg ctttaacagc ttattcttca atttcgattt caagttcatc
     5041 gcctaagtca agcggaactt cttcattcac tgcttcttct ttctttggct catctttttt
     5101 gttttcagta tcttgttctg aaacttcttc tccatcaatc aagccaaatt tagaacggac
     5161 ttgcttatca atttcatcaa agatttctgg gtgctctgcc aagtatttct tagcattctc
     5221 agaaccttgc ccaatttttt catctttgta agaataccaa gcccctgctt ttttgataat
     5281 atccaaatcg cttgcaatct tcaaaagctc accagtctta gaaattcctt ctccgtacat
     5341 aatttcaact acggcttcct taaacggtgg agctacctta ttttttacaa ccttaatctt
     5401 agtttcttta ccgacattgg tttctttttg atcaccagtt cccttaattt gtgtattacc
     5461 acgaacatcc aagcggactg aagcatagaa tttcaaagca cgtccgcccg gtgttgtttc
     5521 tggatttcca aacatcactc caactttttc acgcaattgg ttgataaaaa tggcaattgt
     5581 tttggtttta ttgatagagg cgccaagttt acgcatggcc tggctcatca tacgagcctg
     5641 caaaccaaca tggctatctc cgatatctcc atcaatttcc gcacgaggaa caagggcagc
     5701 aactgagtcg actacgacaa gatcaactgc acctgagtca atcaattttc ccgcaatctc
     5761 aagaccttgc tctcctgagt ctggttgaga caagagcaat tcgtcaatat tgacaccaag
     5821 ggccgcagca taagctggat caagggcatg ttccgcatcg ataaaggcag caatcccacc
     5881 ttctttttgc gcttgtgcaa ctgcatgaag ggcaaccgtt gtcttaccag atgactctgg
     5941 gccatagatt tcgatgatac gtcccttagg ataaccacct gagccaaggg caatgtcaag
     6001 agctaaagaa cctgagctca tcacttgcac cttttgctcc gcacgttcac ccaaacgcat
     6061 gattgatcct ttaccaaagt ctttctcaat caatttaaga gcgtcattca aggccttttc
     6121 acgttctgcc ccaaattttt ttgaaatttc ttctaatttt tttggttttt tcgccattct
     6181 attctcctac attctaatga tcctcagacc tatctactat tatatcaaaa gttagtcact
     6241 taataaagcc ttgcgaacta ggttaaaggc atgcataacc gcaatgtgac gtacatctgc
     6301 tcggcttctg cctccaatat taaccttgat aacctcagtt ccttgatctt gcgccaagcc
     6361 tatgaagact gtcccaactg ggtgtccttc taggctatct ggtcctgcca ctccagtcaa
     6421 actaattcca aaatcagact gggtcttgct tcgtgcctgc tcagccatct tctgagctgt
     6481 aaattcagac accacaccat gttcttccaa attcttggca ggaatatcca acatccttga
     6541 tttttcctcc aagctatagg tcacaaaacc accctcaaat atacttgaaa ctccagaaaa
     6601 attcgccacg gtagcttgga aaagacctgc cgtcaaactc tctgcagccg cgatggtttt
     6661 cccttgcctt ttcagttctt ctaccacaat gctggctaaa ctagtttctt ccccataacc
     6721 atagcaaaag tctcgtaaag aaattccttc gaaagtctgg cagtccaaga tttgattttc
     6781 caagatatcc agcgcttgat tcgcctcttc ttgactgcta gcctttgttg acagacgtag
     6841 agtgacttct cctgtcttgg cataaggggc caaggtagga tcgatctgat tatcaattaa
     6901 atcagccaaa atcgtaacca actggctctc gccaatccca aagaaacgaa gaactcggga
     6961 atacagcttg ttccctgtca tcaacttggg tagaagttgg tttaagacca tgggtttcaa
     7021 ttcacttggc ggacctggaa ggacgacata ggtcactccg tctacttcta attttcctcc
     7081 aacagccagt cctgtttcgt ttggcagtgg aatcgctcct tctacaattt gagcttgtct
     7141 ttcgttattc ggtgttcggg catagtctgg tcgcagggca aaaaagatat ccaacttctc
     7201 ctgagcctga ggatcaaaga ctaatgcttt ccctaaaaat ttagctaggg tttgtttggt
     7261 taggtcgtcc tcagttggcc ccaaaccgcc tgtcaaaatc accagactgc tacgttgact
     7321 ggcaatctca agcaaagaca agagacgaac ttcattgtct cctacagccg tctgaaaata
     7381 tacatctacc ccaatctcag ctagtttttc cgacaaaaac tgggcattgg tgttgacaat
     7441 ctgtcctgtc aaaatctctg ttccaacagc aatgatttct gctttcatgt ttcctcctac
     7501 ctatctattc gtattttttt gaaaaaatcg caggaatttt cctacgattg atttttttat
     7561 ttgtatcaaa agttaattat cttcatcacc aacaggtgct ctgccaaata aatcttcaaa
     7621 taaaaccgca ttggtttcaa gctgagtaac ttcttcttgt cccaaagaac gtcggagtat
     7681 attttgcatt tccaacatat gtgctctcga aacaatctgg taagaaacac cttgaagtat
     7741 ctctccttca ccctgcaact gctgagtttc aatggtttta aatgaatctt tatagcctag
     7801 caagttaggg atactttttg cagacaaatc aatattggtc tgcatattgt cactcaaagc
     7861 ttttagaatc tcttgataat gaccaacgct atttaaactg agagcttttt ccatgacttt
     7921 ttgaataact tcacgttgac gtttttgacg accataatcc ccctcaggat cttggtaacg
     7981 cattcgtgca tagactaggg cttcttctcc cccaatatgt tgctccccaa caccgataga
     8041 aatagtatta aattcttctt ggtcactgat agaaattggg aaacctagga tattattgac
     8101 tgtaatacct cctactgcat ccactagttt ttgcaaccct ctcatattga ccatcacata
     8161 gcgatcaata tggatattca tcattttttg aatggtttct atagcaagct ctgctccacc
     8221 atctgcatat gctgagttca gtttcgcttc atgagcctga ccattccctg attcaatgcg
     8281 cgtcagaata tcccgctcta aactcatcat tgttgttttt ttcgttttag gattcactgt
     8341 catcaagatc atgctatcac ttctaccgac ccaagtttca gttcgttcag catttccggt
     8401 gtccactccc attaacagaa tggttagagg ttcagtcgct tcaataacct tggtttcttc
     8461 gccgattttt ttataggttt tagctaaggt ttctgtccct tgttgataaa tagtataagc
     8521 aaaaacacct actcctacta cagttacaga aagtaaagct agcaccattc caataatttt
     8581 tttaaccata tttctactaa tctatcagtt tacccatcaa gtaaacatcg ataaatttcc
     8641 cttcttctat atatgcccca cgctcttggc taccttcaat gacaaagcca tgcttttgat
     8701 aaagatggac tgctgcttga ttacgagttt ggacagtcag ttggagacga cgcagaatgc
     8761 cacttgcttg tgcccactct atcgcttctt ctagcaacaa acttcccaag ccattattcc
     8821 aatatctttt tccaatcaca atgaagagat ctccaatatg acggactctc ttacgctggt
     8881 cagctgtaat atttacaata ccagcaattt tgccatttaa gaatgcaagt aaggttatct
     8941 gattgtccga actagcttgc ttgttgagga atatttccat ctcctcacta gtcaagagaa
     9001 taccatctcc gtctaggctg gtaaagtctg tctccaaact cacacgattt aaaaaggcca
     9061 ctaattcagc tgcatctttg ggctctgctt ccctaatgag caattcatac tccatattga
     9121 agctcctcta acaatttctc agcacgcaaa ccctttgcct gaaaatttaa acggcgtcca
     9181 tctgcttctt ttagaatttc caattctaaa taagcatctg gcaaggcatc tcctaagaga
     9241 tttccccact caataacagt cacgccgcca ccaaagataa actcatccaa gtcgatagaa
     9301 tcagcatctc cttcaatacg ataaacatct aggtgataaa gtggaagtcg accttcatac
     9361 tctctcacga tagtataggt aggactttta atcatttgag aaatctgtaa tccttttgca
     9421 agtcctttag taaaggtcgt tttacctgca cccagttctc caattaagat taaaacatca
     9481 ttctttgcta atagatggcc caaacgctcc cctaaggctt gcaactcttc ttcatttttt
     9541 gtgtacatac tcttattata ccaaaaactt ttcttttgtg tctattttcc tactaaactt
     9601 atcatcataa catccataaa aaacaggctt tctctaaaag aaaatgagcg taacaatgac
     9661 caatacaaga tctcggaaaa tatgaccata aaaggaaact tccttcttaa ccgaatttgg
     9721 gacaagatag gctgcaaaaa acaagcccag tccagtataa atcagaagtg agacaatggt
     9781 cattggattt cttaagaaaa gaagtgttgc taaaatagtc accaacactg tcttttttct
     9841 gtctagcata gcaagaaaat cgcgcacgta ttttttcaag ggtaaaaaaa tcagcaaatc
     9901 tagcccaaat aggaaaaaga aggatggcaa taaaaagtca actaattctt gctgcagcgt
     9961 atttttgatg aacaagttat ctgacaaaac aagaacagct cctaacaaat taattaagag
    10021 taacatactg taaaaaagct tcaccgactt cttactggct aggacactat ggacttcttg
    10081 cttacgggta taaagataat ttactccagc acagattcct gaaacgaaaa ccatgcttcc
    10141 gatgaaaaaa gctgtacttt gtttaaagga caagatgcat tccttccata ggaaacagct
    10201 actcaaactg atttgaatta aagctaacaa aaataagatt ctcattgatt tcatcttctc
    10261 tctcccttcc taccaatcat tatactcgga gaaaagagag aactgtttcc aatcttccca
    10321 aatgtctttt taagacgcta aacaaacacg agaggctaat actcaatgaa aatcaaagag
    10381 caaactagga agctagccgc aggttgttca aaacactgtt ttgaggttgc agatagagct
    10441 gacgtggttt gaagagattt tggaagaata taaacttgaa ataaggctga tagtattcat
    10501 ttcactatca gccttacagg ttatttaacg tttcagaaaa actataatgt caagattaac
    10561 tatacagtat ctaattcctt caaataattt tctatcttca tcaacattaa aggattgtta
    10621 taaatcttac ataactctct tgcttctata taataatttt tgacttgttc tttgtctaga
    10681 aatttggctc cagcatttcc tacaagaata agtaggggag ccagttggta gcttgtctgt
    10741 ctttgtttac agagttcaat cgtctcaaga gcttcttgga tagcttcgtt atatttttcc
    10801 tttgacacta ggtagtgaga gtagttgtaa cgaactctga tgtagccaaa taaaaactct
    10861 tgatgctcaa aattttttgt ctgatataac tccattaaat gagagtagtt tgcctcatat
    10921 tcttgttcac gacccactaa ggaatagaaa ttagatagag tattcaatgc ctttaaataa
    10981 atcagagtat ttgaggagac ttttaataat atattttcca atgaagaaat agcctcacac
    11041 ttactgtcat attgatagaa gtcaataata gctttaatcc attcaaggta agttcggtct
    11101 tctagtgtta gaaaagtact tcgttcaatc tctattctat aaatatattc caaattgtca
    11161 taatttctgt catctaatag tcgagcagat aattgcttga aattagagag gttagattta
    11221 atttcaattt gttcattaaa aaaataatct aatggtactt caagtcgttg tgagagtttg
    11281 aacaaaaggt ctgcggaggg aatgaaatgc cctctctcaa ttttactaat ctggctttgt
    11341 tcacaaattc cttctgcaag agtttgttgg gagagtccta gctcttttct ttttaatctg
    11401 aatttctctg cgagtgtatt cattaaagat aataaacctt cctatttgct taatttcatt
    11461 ataaaatttt tagttcaaaa tagcaagtta aaagaataaa taattcttta tagtaataaa
    11521 aaaaaaaaaa agttcaaaat gcaataaaaa taattgactg aataaactac atatgttaga
    11581 ataaaaacaa ggaaaaagaa aggggtttca ttgcatgaga aaaaaacgtg gaattaaaaa
    11641 attagttaca tttgcattac taggtgtttt tatgtttagt aatacaattc cttaccaaca
    11701 gtttattcag aagaataaac aattggaagt tcgagtacaa tcacaaaagg agtccaatgg
    11761 tcttgatgtt gggaaggctg attagttgat taaatgatga aaatactaat taactatatg
    11821 gtatttctgt tttatctaat ttttaattag aaaaatagca taaaaatcta gttatccgca
    11881 taaaaactgg acttatcaca ctttatcaag gtcaaaacca ctcaatttac tactaattta
    11941 ctacttatga atgagctttg atacgacgat ttatccttga aaagtgaaga tataaagata
    12001 cttccaataa aatttgaata tttaataggt agacacttca aaaaatgagg tgtctatttt
    12061 tttacccgat tttgaaagga agtgaactta tgaaaacaaa aaatcaagaa tcaaaaggtc
    12121 gttccccact ctttaagacc atcaaacatt cattcagcca ataaaaaaga aaggataggt
    12181 aaaaatatgg aacttaaatt tgtgattccc aacatggaaa aaacattcgg caatttagaa
    12241 tttgctggcg aggataaagt cgttcagcga agaatcaacg gacggctaac tgtcttatca
    12301 agaagctata atctctattc tgatgttcaa agagcagatg atattgtggt ggtgcttcct
    12361 gctgaagctg gcgaaaaaca tttcggcttt gaggaacgtg tgaagttagt caatccacgt
    12421 attaccgcag agggctacaa aatcggcact cgtggtttta caaattacct tttacatgct
    12481 gacgacatga taaaagaata aagaaagaga ggaaaaatga tgagattagc aaatggcatt
    12541 gtattagata aagacacgac ttttggagaa ttgaaattct ctgctctacg tcgtgaagtg
    12601 agaatccaaa atgaagacgg gtcggtttca gatgaaatca aggaacgtac ctatgactta
    12661 aaatccaaag gacaaggacg catgattcaa gtaagtattc ctgccagcgt gcctttgaaa
    12721 gagtttgatt ataacgcacg ggtggaactt atcaatccca ttgcggacac cgttgctact
    12781 gccacctatc aaggagcaga tgttgactgg tatatcaagg cagacgatat tgtgctgaca
    12841 aaggattcta gttcattcaa agctcaacca caagcaaaga aagaaccgac acaagacaaa
    12901 tagtcgctag gtagaaagga gactttttcg catgaaacag cgtggtaaaa ggattcgccc
    12961 atctggtaaa gatttagtct ttcattttac gatagcgtca ctcctgcctg ttttcctgct
    13021 ggttgtcgga ctgtttcatg tgaagacaat ccagcagatc aactggcagg attttaacct
    13081 atcacaagca gataagattg acattcccta tttaattatc agtttcagtg tcgcaattct
    13141 tatctgcttg ctggtagcgt ttgtattcaa acgggttcgc tatgatacgg ttaaacaact
    13201 ttaccaccgt caaaaactgg caaagatgat acttgaaaac aagtggtatg aatctgaaca
    13261 ggtcaaaaca gagggtttct ttaaagatag tgctggtcgt acaaaggaaa agataaccta
    13321 cttccctaaa atgtattatc gacttaaaaa tggcttgata cagatacggg tggaaatcac
    13381 gctgggaaaa tatcaagacc aactcttaca cttggaaaag aaattagaga gtggcttgta
    13441 ctgtgagctg acggataaag agttaaagga ttcctatgtg gaatatactt tgctctatga
    13501 caccatagcc agtcgtattt ctattgatga agtacaagct aaagatggta aacttcgctt
    13561 aatgaaaaac gtatggtggg aatatgataa gctccctcat atgttgattg ctggtggtac
    13621 aggtggcggt aaaacttact ttatactgac actgattgaa gccttgcttc atacagattc
    13681 aaaactgtat attcttgacc cgaaaaatgc tgaccttgcg gacttaggtt ctgtgatggc
    13741 aaatgtctac tatagaaaag aagacttgct ttcttgcatt gaaacattct atgaagaaat
    13801 gatgaaacgt agtgaggaaa tgaagcagat gaagaactat aagactggca aaaattatgc
    13861 ttacttaggt ctcccggcac acttcttaat ctttgatgaa tacgtcgctt tcatggaaat
    13921 gctgggaaca aaagaaaaca ccgcagttat gaataagctg aaacagattg tcatgttagg
    13981 tcgtcaagct ggcttctttc taatactggc ttgtcaacgt ccagacgcaa aatatttagg
    14041 cgacggaatc cgtgatcagt ttaatttcag agtggcttta ggtcgtatgt ctgaaatggg
    14101 ctatggcatg atgtttggca gtgacgtaca aaaggatttc ttcttaaagc gaatcaaagg
    14161 tcgtggctat gttgatgtag gaacaagtgt catatcagag ttttatactc cccttgtacc
    14221 aaaaggatat gatttcttgg aggaaattaa aaagttatcc aacagcagac agtccacgca
    14281 ggcgacgtgc gaagcggaag tcgcaggtgt ggactgatct tgctggctgg tgtggcaata
    14341 gccacgccag cacttaaccc cccgtatcta acaggggggt acaaatcgac aggaaacagt
    14401 caaaaaaaca ttagaaaatc ctttggttac aagggattta caaaatttca gcgtatgtca
    14461 aatgggcttt aaaagttgac atacgccttt ttgattggag ggatttttac tgaatgaaca
    14521 aacttggtta cagcagttaa aagaaaaacg cttggcttat ggactatctc aaaatcgttt
    14581 agcggttgcg actggtatta caaggcagta tctaagcgat attgaaacag gaaaagtcaa
    14641 gccatcagag gatttacagc aatctctttt tgaagctctg gaacgcttca atcccgacgc
    14701 tccccttgaa atgctctttg attatgtaag gattcgcttt cccacaacgg acgtacagca
    14761 tgtggtcgaa aacatcttac aactgaaact gtcctatttt cttcatgagg actatggttt
    14821 ctattcttat tcagagcatt atgctttagg cgatatattc gttctctgct cccacgaact
    14881 ggacaaagga gttctggtgg aattgaaagg tcgtgggtgt cggcaatttg aaagctatct
    14941 tctggctcaa caaagaagct ggtatgagtt ctttatggac gctttggtgg ctggcggtgt
    15001 gatgaaacgc cttgaccttg ccattaacga taagacaggg attttgaata tccctgtact
    15061 cactgaaaag tgccaacagg aagaatgtat ctccgtcttc cgcagtttta aaagctatcg
    15121 cagtggcgaa ctggtacgca aagaggaaaa ggaatgtatg ggaaacaccc tctatatcgg
    15181 ttcattacaa agtgaagttt atttctgtat ctatgaaaag gactacgagc agtacaagaa
    15241 aaatgatatt cccattgaag acgcagaagt aaaaaaccgt tttgagattc gattgaaaaa
    15301 tgagcgtgcc tattatgcag tccgtgattt actcgtctat gacaatccag agcataccgc
    15361 ctttaaaatt atcaatcggt atatccgttt tgtagataaa gacgattcca aacctcgttc
    15421 tgattggaaa ctgaatgaag aatgggcttg gtttattggg aacaatcgtg aacgattaaa
    15481 actaaccaca aaaccagagc cttactcctt ccaaaggacg ctgaactggc tatctcatca
    15541 agttgccccg accttaaagg ttgcgattaa acttgatgaa atcaaccaga cgcaggttgt
    15601 aaaagacatt ctcgaccatg cgaaactgac agaccgacac aagcagattt tgaagcaaca
    15661 gtcagtaaaa gaacaggacg tgataacaac aaaaaaagga tatctgtcaa ccataccagt
    15721 tgacagatat ccaaaaaaaa gatataatgg gagataagac ggttcgtgtt cgtgctgact
    15781 tgcaccatat cataaaaatc gaaacagcaa agaatggcgg aaacgtaaaa gaagttatgg
    15841 aaataagact tagaagcaaa cttaagagtg tgttgatagt gcattatctt aaaattttgt
    15901 ataataggaa ttgaagttaa attagatgct aaaaatttgt aattaagaag gagggattcg
    15961 tcatgttggt attccaaatg cgtaatgtag ataaaacatc tactgttttg aaacagacta
    16021 aaaacagtga ttacgcagat aaataaatac gttagattaa ttcctaccag tgactaatct
    16081 tatgactttt taaacagata actaaaatta caaacaaatc gtttaacttc tgtatttgtt
    16141 tatagatgta atcacttcag gagagattac atgaacaaaa atataaaata ttctcaaaac
    16201 tttttaacga gtgaaaaagt actcaaccaa ataataaaac aattgaattt aaaagaaacc
    16261 gataccgttt acgaaattgg aacaggtaaa gggcatttaa cgacgaaact ggctaaaata
    16321 agtaaacagg taacgtctat tgaattagac agtcatctat tcaacttatc gtcagaaaaa
    16381 ttaaaactga atactcgtgt cactttaatt caccaagata ttctacagtt tcaattccct
    16441 aacaaacaga ggtataaaat tgttgggaat attccttacc atttaagcac acaaattatt
    16501 aaaaaagtgg tttttgaaag ccgtgcgtct gacatctatc tgattgttga agaaggattc
    16561 tacaagcgta ccttggatat tcaccgaaca ctagggttgc tcttgcacac tcaagtctcg
    16621 attcagcaat tgcttaagct gccagcggaa tgctttcatc ctaaaccaaa agtaaacagt
    16681 gtcttaataa aacttacccg ccataccaca gatgttccag ataaatattg gaagctatat
    16741 acgtactttg tttcaaaatg ggtcaatcga gaatatcgtc aactgtttac taaaaatcag
    16801 tttcatcaag caatgaaaca cgccaaagta aacaatttaa gtaccattac ttatgagcaa
    16861 gtattgtcta tttttaatag ttatctatta tttaacggga ggaaataatt ctatgagtcg
    16921 cttttttaaa tttggaaagt tacacgttac taaagggaat ggagataaat tattagatat
    16981 actactgaca gcttccaaga agctaaagag gtccctagcg cctacgggga atttgtatcg
    17041 ataaggggta caaattccca ctaagcgctc gggacccctt gtaggaaaat gtcctaagtg
    17101 ggatatctgt caactggtat ggttgactaa aaatacttcc tacgaaaatg tagggggtat
    17161 ttttttacga aaaaatacaa tcgattctta aaaagaaaaa tttttgattg gcaaaaccat
    17221 aacaagttcg ttttagggtt ttgattttgc gattgatgcc ttctaaagga ccattagagt
    17281 attcaaattt agcgctattt aagacatatt ttctgttttg acgaagggtt tgaatagcag
    17341 tatccatttc tgtattggtt ttttggtagt ctaagatggt tgactctagt aattcactat
    17401 tgcgctcgtt tagggctttc gtgatatctt ggtaagtttg gtatacttca gcgaacttgg
    17461 aaaatttact agtaatgaga tcaacagcat tttggcgagt catatattgt ttaacgccgc
    17521 gaagaaaaac tacttcttca gggtgaagat cttcagcttt tttatggaat agcttccaat
    17581 gtgacttcat aattttatat tcttggctct gtttatcaag ttgctttagg atagagatac
    17641 gacaattgtc caaagcgcga ccagctaatt gtacaaggtg gaagcgatca ataatgatat
    17701 tggcattagg gaaaaggcga tagataaaac tttgatattg agcatttaaa tcaattacaa
    17761 ctgattgaac gcattcgcgt tcggcttttg aataacgact ttcaaaataa tcaacaatgg
    17821 taggtgatag acgatcctgt aactttgtga caatttggtg ggtttcagcg tcacaacaga
    17881 taaaggacat cacagactta attgaacgaa actcgtcaaa acatagatgc ttaggcaact
    17941 tagccacacg atagtgtggt tccatgcgct ctaagattgt tcgacgaaca ctgctaggag
    18001 agcagtgaca catttcagca ataagctgac cagataagcc tttacgagct aaaagcatga
    18061 tttgattttt gagatcactg gataaggttt gattttcttt ggttaaatta gtaatagcac
    18121 caaaagtagt atggcatgat ttacatttat agcgttgttt acgaagctct agttcatatc
    18181 ttctcccatt taaacttgcc agtcgtacat gagttttgcg aaagccatcc ttattaactg
    18241 tgggaaagcc acagttacga caacgattaa tcggataaga aagagtagct gttattagcg
    18301 ttatatactc tttaacagaa tcgttgttgt gttcagcttc ttcaacagaa ataattttaa
    18361 tatttttatc tttaattcca agaatattta ggatagaatc attatgggac atttgtttaa
    18421 ccttctttca tgatttttgt ggtgaattga ttgtataacg aggggacagc aaatgtcctc
    18481 ttttttgtat aaaaaaatct ggcatggaat ctctatccat accagaaagt gtatacccca
    18541 aaaaaataac tcaaatacaa attcattgaa tatagagagg agaacatttt tatgaatttt
    18601 ggacaaaacc tttataactg gtttctatca aacgctcaat cactggtgct tttagcaatc
    18661 gttgtgattg gcttgtatct tggcttcaag cgtgagttta gcaaactgat tggcttttta
    18721 attattgcga ttattgcggt tggcttagtc ttcaacgctg ctggagtaaa agacatttta
    18781 ctagagctat tcaatcgcat tattggtgct taaataaaac cgttcttttg tggaatataa
    18841 gtggttttct tatgttccgc aaaggaatgg tacaccaaac gaagtgcggt agggattttt
    18901 gaatctctac aaagaaagga cgtgaatata tggacgatat gcaagtctat attgcgaatt
    18961 taggcaaata caatgagggc gaattggtcg gtgcgtggtt tacctttccc attgactttg
    19021 aggaagtcaa agagaaaatc ggcttgaatg atgaatatga ggaatacgcc attcatgact
    19081 acgagttacc ctttacggtt gacgaataca cttccattgg cgaactcaat cgactatggg
    19141 aaatggtatc ggaattaccc gaagaattac aatcggagct atctgctctg ctcactcatt
    19201 tttcaagcat tgaagaacta agcgaacatc aagaggatat tatcattcat tccgattgtg
    19261 atgatatgta tgacgtggca cgctactaca ttgaagaaac gggtgcttta ggcgaagtac
    19321 cagctagtct tcaaaactat attgattatc aagcctatgg tcgggattta gacctttcag
    19381 gaacgtttat ctcaaccaat catgggattt ttgaaatcgt ctattaaatc tgtcggtaca
    19441 ttactactgg cagattttct attttacggg gtggctcaat cagctacccc tattttttat
    19501 gaaaggattg attacatgaa gaaaatacga agctatacca gtatctggtc tgtggaaaag
    19561 gtactgtatt ctatcaatga ttttagactt ccgtttccca taacctttac gcaaatgaca
    19621 tggtttgtcg tgtcactctt tgcagtgatg atacttggca acttgccccc tctttccatg
    19681 atagagggag catttctcaa atactttggg attcctgtgg ctttcacatg gtttatgtct
    19741 acaaaaactt ttgatggtaa aaagccttat ggatttttga agtctgtcat tgcttatgca
    19801 ctgcgaccaa agctgaccta tgcaggaaaa aaagtaacgc ttggcagaaa ccagccacaa
    19861 gaagccatta cagcagttag gagtgaattt tatggcatat ccaattaaat acattgaaaa
    19921 caatctcgtc tggaataaag acggggaatg ttatgcttac tatgagcttg ttccttacaa
    19981 ttactcattt ctaagtccag aacagaaaat acaagtgcat gattctttca gacagcttat
    20041 cgcacaaaat cgtgatggca aaattcatgc tttacaaatc agtacagaat ccagcatacg
    20101 ttctgcacaa gagcgttcca aaaatgaagt cactggcaag ctcaaagcgg ttgcctatga
    20161 caaaatcgac caacagacag acgctttaat atccatgatt ggcgaaaatc aagtgaacta
    20221 ccgtttcttt atcggcttta agttgcttct caacgatcag gagttttcta tgaaaagtct
    20281 taccgttgaa gcaaaaaatg ctttgtctga ttttgtctat gatgtgaacc ataagctgat
    20341 gggcgatttt gttagtatga gtaatgatga aatcctgcgt tttcagaaga tggaaaagct
    20401 cttagaaaat aaaatctctc gtcgtttcaa aatccgcagg ttagataagg acgacttcgg
    20461 ctatctgatt gaacaccttt acggacagac aggcactgcc tatgaagagt atgagtacca
    20521 tctatcaaag aaaaagctgg ataatgaaac gctgattaaa tactatgact tgattaagcc
    20581 tactcgctgt ttggtggaag aaaaacagcg atatttgaaa atccagcagg aagatgaaac
    20641 cgtctatgta gcttacttta ccattaacag cattgtcgga gaactggact tcccgtcctc
    20701 tgaaatcttc tactaccagc aacagcaatt tacattcccg attgatacgt caatgaatgt
    20761 ggaaattgta gcgaatcgta aagccctatc tactgtccgc aataaaaaga aagaactgaa
    20821 agacttggat aaccacgcat ggcaaagtga taatgaaacc agctctaatg tggcggaagc
    20881 tctggaaagt gtgaacgagc tggaaaccaa tttagaccaa agcaaggaat ctatgtataa
    20941 gctgtcctat gttgtaaggg tatcagcaaa tgaccttgac gaacttaaac gtcgttgtaa
    21001 tgaagtgaaa gatttctatg atgatttgag cgtgaaactg gtacgacctt ttggggatat
    21061 gctgggctta catgaagaat ttttacctgc cagcaaaaga tatatgaatg actatattca
    21121 atacgtgacc tctgatttcc tcgctggttt aggttttggt gctactcaaa tgctgggtga
    21181 aaatgagggg atttatgttg gctacagctt agatactgga cgcaatgtct atctgaaacc
    21241 tgctcttgcc agtcaagggg ttaagggttc agtaaccaat gcgttagcgt ctgcctttgt
    21301 cggttcgctg ggtggtggta aatcctttgc gaataacctt atcgtctatt atgcagtgct
    21361 ttatggggca caagcagtga ttgtagaccc aaaagcagaa cgtggcagat ggaaagaaac
    21421 cttgccagag atttcccatg aaatcaatat cgtcactctg acttctgatg agaaaaacaa
    21481 aggcttactt gacccttatg tgattatgaa aaatcccaaa gattctgaat cactggctat
    21541 tgatattctg acattcctta cggggatttc ctctcgtgat ggggaacgct tcccaatcct
    21601 tagaaaagcc attcgtgcag taaccaatag tgaagtacga gggttgatga aagtgattga
    21661 ggaattacgg gttgagaata cgccactaag taccagtata gccgaccata tcgaaagttt
    21721 tacagactat gactttgcac atttattatt cagtaatggt tatgtggagc agtctatcag
    21781 cttagaaaaa caactgaaca ttatacaggt tgcggacttg gtacttcccg acaaggaaac
    21841 ttcctttgag gaatatacca ctatggagct tttatccgtt gctatgctga ttgtcattag
    21901 tacctttgct ttagacttta tccatacaga ccgaagcatt ttcaagattg tagatttaga
    21961 cgaagcatgg agctttttac aggtagcaca aggaaaaaca ctatctatga agctggttcg
    22021 ggctggtcgt gctatgaacg ctggggtata tttcgtgacc caaaatacag acgacctctt
    22081 agatgaaaaa ctgaaaaata acctcggctt aaaatttgca tttcgttcca ctgaccttaa
    22141 cgagattaaa aagaccttag ccttttttgg tgtagaccca gaggacgaaa acaatcagaa
    22201 gcgattgcgt gatttggaaa acgggcaatg ccttatcagt gatttatatg gtcgtgtcgg
    22261 tgtgatacag ttccaccctg tatttgaaga actgctccat gcctttgata ccagaccacc
    22321 tgtgcgaaaa gaggtgtaaa tgtgaaacca tcaatagtaa acagaataaa atcaaactgg
    22381 acgctgaaac gtctaggtaa agtggcaatg acagtggctt tcacacttgt gattgccatt
    22441 tttcttttag ccatgctggg aacggtggtt caagctgcgg gcttggtaga tgatacggtc
    22501 aatgtggcaa atgaatacag ccgataccca cttgaaaact atcaactgga tttttatgtg
    22561 gataatagct ggggctggct tccgtggaac tggtcggacg ggattggaaa acaggtcatg
    22621 tatggactat atgccattac caattttatt tggacaatca gtttgtatgt ttccaatgcg
    22681 acaggttact tagtacagga agcctattcc ttagacttca tttccgctac agcagattcc
    22741 attggtaaga atatgcagac cttagctggt gtgagtgcaa acggattttc aacagagggt
    22801 ttctatgttg gattcctctt actcttgatt ttggttcttg gggtttatgt tgcctatacg
    22861 ggactgataa agagagaaac cacaaaggca attcatgcca ttatgaattt tgtgctggtg
    22921 tttatcctat cggcttcctt tattgcctac gctcccgact acattaaaaa aatcaatgac
    22981 ttttcatcag acatcagtaa tgccagttta tcacttggca cgaagattgt catgccccat
    23041 tccgatagtc aaggcaagga cagcgtggac ttaatcagag atagcctgtt ttccatacag
    23101 gttcagcaac cgtggctact gcttcaatac aacagttcag acattgaaag tatcggtatt
    23161 gaccgtgtgg aaagcctgct ctccaccagc ccagattcca acaatggcga agacagagaa
    23221 aaaattgttg cggaagaaat tgaagacaga agcaatacca atctaaccat tacaaagacc
    23281 attaaccgtt taggtacagt cttcttccta tttgtcttca atattgggat ttccatattt
    23341 gtattcctat taacaggaat catgattttc tcgcaggtac tttttatcat ctatgctatg
    23401 tttctgcctg tgagctttat tttaagcatg attccatcat ttgatggtat gtcaaaacga
    23461 gccataacaa agctctttaa taccattttg acacgagctg gaatcacatt gattattacg
    23521 acagcattta gtatttcaac catgctctat accttatcgg ctggttatcc gttctttttg
    23581 attgcttttc tacagattgt gacctttgca ggaatctact tcaagctggg cgatttaatg
    23641 agtatgtttt ctctacagag taacgattct caaagtgtgg gaagtcgtgt gatgagaaaa
    23701 cctcgtatgc ttatgcacgc tcacatgcac cgtctacagc ggaaacttgg acgttccatg
    23761 actactctag gggctgggtc tgccattgtt acaggtaaaa aaggacagtc gggttcgggg
    23821 agttctgcaa ggacacaagc agatcactcc cgaccagacg gaaaggaaaa atcaacactt
    23881 ggaaaacgta tcggtcaaac catcggtaca gtagctgata ccaaagacag aatggtagac
    23941 actgctagtg gtttgaaaga acaggttaaa gatttgccga ccaatgcaag atatgcagta
    24001 tatcaaggaa aatccaaagt aaaagagaat gtccgtgatt taaccagtag tatttctcaa
    24061 accaaagcgg aaagagccag tggacgcaag gaacagcagg aacaaaggcg aaaaaccatt
    24121 gcgaagcgtc gctctgaaat ggaacaggtc aaacagaaaa aacagcctgc ttcttctgtt
    24181 catgaaagac cgactacaag acaagaacaa tatcatgatg aacagacctc aaaacagtct
    24241 aatattcaga cttcatataa ggaatctcaa caagccaaac aagagcgtcc agcagttaag
    24301 tccgattttt caagtccaaa agtggaacgc caaggcaata ccgttcaaga aaaaaccgtt
    24361 caaaagccag caacttcaac cactacagca gatagaactt cacaacgtcc aatcacaaaa
    24421 gaacgtccgt ctactgttca aagagtacca ctacaaaata caagaagtag accaccaatc
    24481 aaaaccgcca ccattaagaa agtcggtaag aaaccatgaa gttgaaaact ttagtgattg
    24541 gtggttctgg attattcttg atggtcttct cactgcttct gtttgttgcc attttatttt
    24601 cagatgaaca ggacagcgga atttccaata ttcattatgg aggtgtgaat gtttccgcag
    24661 aagtgctggc tcataagcct atggtagaaa aatatgccaa agaatatggc gttgaagaat
    24721 atgtcaacat acttcttgcg attatacagg tggaatcggg cggtactgcg gaagatgtta
    24781 tgcagtcctc ggaatccctc ggtcttccac ctaattcatt gagtacagaa gaatccatta
    24841 agcaaggtgt gaagtatttc agtgaattat tagccagtag cgaaaggctc agtgtagatt
    24901 tagaatcggt tatccagtcc tacaattatg gtggtggttt cttagggtat gtggctaatc
    24961 gtggaaataa atataccttt gaactggctc aaagtttctc aaaagagtat tcaggtggcg
    25021 aaaaagtgtc ttaccccaat cccatagcca tacctatcaa tgggggctgg cgatacaact
    25081 atggcaatat gttttatgtg caactggtaa cgcagtatct tgtcacaaca gagtttgatg
    25141 atgatacggt acaagccatc atggacgaag cactgaaata tgagggctgg cgatacgttt
    25201 acggtggagc ttccccgact acttcttttg attgtagcgg actgacacaa tggacgtatg
    25261 gaaaagctgg aattaactta ccacgaaccg cacaacagca atatgatgtg acccagcata
    25321 tcccactatc ggaagcacaa gctggcgatt tggttttctt tcattctacc tataacgctg
    25381 gctcttatat tactcatgtt gggatatacc ttggcaataa ccgtatgttt catgcaggcg
    25441 acccaatcgg ttatgccgac ttaacaagcc cctactggca acagcattta gtgggagcag
    25501 gacgaatcaa acaatgagaa aggaagattt aatgatgaaa tttagaaaaa atcagaataa
    25561 agaaaaacag ataccaaagg aaaagaaacc tcgtgtctat aaggtcaatc ctcataaaaa
    25621 ggttgtgatt gccttgtggg tacttttagg gcttagtttc agctttgcga tattcaagca
    25681 ctttacagct atagatactc atactattca cgaaacaact atcatagaaa aggaatacgt
    25741 tgatactcat catgtagaaa attttgtaga gaactttgcg aaagtctact attcatggga
    25801 gcaatccgat aagtccattg ataatcgaat ggaaagtcta aaaggctatc tgacagatga
    25861 acttcaagct ctcaatgttg atacagtacg caaagatatt cctgtatcgt cttctgtaag
    25921 aggatttcag atatggacgg tagagccaac tggcgacaat gagtttaatg taacctacag
    25981 tgtagaccag ctcattacag agggagaaaa tacaaagacc gtccactctg cttatatagt
    26041 gagtgtctat gtagatggtt ctggaaatat ggtactggtt aagaatccga ccattaccaa
    26101 catacctaag aaatcaagtt ataaaccaaa agccattgaa agtgagggga cggttgattc
    26161 cattacaacc aatgaaatca atgagttttt aacgacgttc ttcaagctct atcctacagc
    26221 gacagccagt gaactttcct actatgtgaa tgacgggata ttaaaaccaa tcggaaaaga
    26281 gtacatcttt caagaactgg taaatcctat tcacaatcgt aaggataatc aagtcacggt
    26341 atcgctgaca gtggagtata tcgaccagca gaccaaagca acgcaggtat ctcaatttga
    26401 tttggtactt gaaaagaacg ggagtaattg gaagattata gaataacaaa tattggtaca
    26461 ttattacagc tattttgtaa tcacgtactc tctttgataa aaaattggag attcctttac
    26521 aaatatgctc ttacgtgcta ttatttaagt atctatttaa aaggagttaa taaatatgcg
    26581 gcaaggtatt cttaaataaa ctgtcaattt gatagtgcga acaaataatt ggatgtcctt
    26641 ttttaggagg gcttagtttt ttgtacccag tttaagaata cctttatcat gtgattctaa
    26701 agtatccgga gaatatctgt atgctttgta tgcctatggt tatgcataaa aatcccagtg
    26761 ataagagtat ttatcactgg gatttttatg cccttttggg cttttgaatg gaggaaaatc
    26821 acatgaaaat tattaatatt ggagttttag ctcatgttga tgcgggaaaa actaccttaa
    26881 cagaaagctt attatataac agtggagcga ttacagaatt aggaagcgtg gacaaaggta
    26941 caacgaggac ggataatacg cttttagaac gtcagagagg aattacaatt cagacaggaa
    27001 taacctcttt tcagtgggaa aatacgaagg tgaacatcat agacacgcca ggacatatgg
    27061 atttcttagc agaagtatat cgttcattat cagttttaga tggggcaatt ctactgattt
    27121 ctgcaaaaga tggcgtacaa gcacaaactc gtatattatt tcatgcactt aggaaaatgg
    27181 ggattcccac aatctttttt atcaataaga ttgaccaaaa tggaattgat ttatcaacgg
    27241 tttatcagga tattaaagag aaactttctg ccgaaattgt aatcaaacag aaggtagaac
    27301 tgtatcctaa tatgtgtgtg acgaacttta ccgaatctga acaatgggat acggtaatag
    27361 agggaaacga tgacctttta gagaaatata tgtccggtaa atcattagaa gcattggaac
    27421 tcgaacaaga ggaaagcata agatttcata attgttccct gttccctgtt tatcacggaa
    27481 gtgcaaaaaa caatataggg attgataacc ttatagaagt gattacgaat aaattttatt
    27541 catcaacaca tcgaggtcag tctgaacttt gcggaaaagt tttcaaaatt gagtattcgg
    27601 aaaaaagaca gcgtcttgca tatatacgtc tttatagtgg cgtactgcat ttgcgagatt
    27661 cggttagaat atcggaaaag gaaaaaataa aaattacaga aatgtatact tcaataaatg
    27721 gtgaattatg taaaatcgat aaggcttatt ccggggaaat tgttattttg cagaatgagt
    27781 ttttgaagtt aaatagtgtt cttggagata caaagctatt gccacagaga gagagaattg
    27841 aaaatcccct ccctctgctg caaacaactg ttgaaccgag caaacctcaa caaagggaaa
    27901 tgttacttga tgcactttta gaaatctccg acagtgaccc gcttctgcga tattatgtgg
    27961 attctgcgac acatgaaatc atactttctt tcttagggaa agtacaaatg gaagtgactt
    28021 gtgctctgct gcaagaaaag tatcatgtgg agatagaaat aaaagagcct acagtcattt
    28081 atatggaaag accgttaaaa aaagcagagt ataccattca catcgaagtt ccaccgaatc
    28141 ctttctgggc ttccattggt ttatctgtat caccgcttcc gttgggaagt ggaatgcagt
    28201 atgagagctc ggtttctctt ggatacttaa atcaatcatt tcaaaatgca gttatggaag
    28261 ggatacgcta tggctgtgaa caaggattgt atggttggaa tgtgacggac tgtaaaatct
    28321 gttttaagta tggcttatac tatagccctg ttagtacccc agcagatttt cggatgcttg
    28381 ctcctattgt attggaacaa gtcttaaaaa aagctggaac agaattgtta gagccatatc
    28441 ttagttttaa aatttatgcg ccacaggaat atctttcacg agcatacacc gatgctccta
    28501 aatattgtgc gaacatcgta gacactcaat tgaaaaataa tgaggtcatt cttagtggag
    28561 aaatccctgc tcggtgtatt caagaatatc gtagtgattt aactttcttt acaaatggac
    28621 gtagtgtttg tttaacagag ttaaaagggt accatgttac taccggtgaa cctgtttgcc
    28681 agccccgtcg tccaaatagt cggatagata aagtacgata tatgttcaat aaaataactt
    28741 agtgtatttt atgttgttat ataaatatgg tttcttgtta aataagatga aatatttttt
    28801 aataaagatt tgaattaaag tgtaaaggag gagatagtta ttataaacta caagtggata
    28861 ttgtgtgctg agagctttct tctatactaa tagacgaaag ggtgtgaaaa tgatttttaa
    28921 atgatactgt ggaacggaac agtagcccta gtattgacta ctgtcgtttc tattcatatt
    28981 ggctattcta ggactgagat gaaaaaatct ataaatgctc agaataaaat tgaacccgca
    29041 aatctcccca aaacaatggt gagtcatgta cttgtattat tccgaaaaaa tacacctctg
    29101 gtgcagtgag acaaattggt gtatcttata gtggcttcgt agatgaaagc tatactctac
    29161 tatcactctt tgatgatgta gaacaaattg aaaaagataa tagacttcag acagctattg
    29221 atgttgtcag agaacagttt ggttttttag ccatacaaaa aggaaccgtc ctaactgaag
    29281 gttccagaaa tattgaacgc agtaaactta tcggtggtca ttccgcgggt ggattggagg
    29341 gattaaaatg aaacaagaaa aaaatacagt acaattttca gaaatccgta gcaaaggatg
    29401 taatgatatt gaaatgcttg aaagattttt acatggaatc gttgaaacag caacttcaaa
    29461 acttcgtcag agaaaactca aaacaactga aatatcgata cgactagtac atgctaaatc
    29521 tgaaaaccga ttaccattgg aatttacatt tagcattaag ccaacaagct catctgtgat
    29581 aatctatact gaggtaatca atcgctttaa agaatgttac acaggtgggg gaattcaagg
    29641 ttttacgatt caatttgata aaaataccct tgcctctgca tagaaaggat ttgatatgat
    29701 tgaccgttca tatttaccat ttcaatcagc aagagagtac caggatacaa agatgcaaaa
    29761 atggatgggc tttttcctat ctgaacatgc atcagcactc tctgatgata caaacaaagt
    29821 aacgtacatg tctgacttat cactagagaa gaaattatta ctcctcagtc aagtatacgc
    29881 cgggcagcta cgcacacgca ttcaagtgat tgaaaaaaac aagcgtgttt cctacactgg
    29941 aacaatacca agtctgacca aagatttcat tttgataaaa actacaacag gtcacatcaa
    30001 tttgaaatta aaagacatta ttagtattga acttgtcgag gaggtgctct atgaatcagc
    30061 ttgagtttca gcgtaatcac ctacaaatgg actattatag cgagagctac caagattttg
    30121 aacgtgactt ctaccgctac tctaacatga atattccatt gaccttccta actgatgata
    30181 tcctaaaaac aatggcgact tcacgtaaga attactttgt cctcaataag gaaaagtcca
    30241 gagataaccg cgatcacttc ttcatatttg aagtaagtac cgtagatgag aatccgctaa
    30301 tctatcatta tacatataag aaaactacaa tatatttagc agaaaaatag gagcagttca
    30361 attgactgtt cctattttta atattcataa aatctaaagt ctttatactc tttaacaatg
    30421 gagtcgccaa ccagaacaga ctatactgac cagcgactac cttaaattta atgtttcaga
    30481 tttattttct tatctctaat ttcataaact acatctgcta cattttcgag taatcgttta
    30541 tcgtgggtga taaacacgat agttccggtg tactccttca ttagtatttc caaagcctct
    30601 aaacttggta tgtcaaggaa gttactgggt tcatccatta ttaggatgtt atatctaccc
    30661 atgagcattt tagcaagcaa caattttata atttctccac cgcttaaaac agataaactt
    30721 tttccaatat cgttctgttt gaaccccata gatgctagca ctgaacgaat ttctgatata
    30781 ttgtagtcac aatccttctg cataaactcc ataacattct gattactgtt gtacttgtaa
    30841 ccattctgtg caaagtaacc tatttttgcc ttaggcgaaa tagaaattcc ttcttcatgg
    30901 tttaagatca tttggattaa agttgttttt ccgattccat taccaccagt taacgccact
    30961 tttgctccta acggaatttg aaaagatgca ttttcaaaca gagccttatc cccaaatact
    31021 ttattaattt ctgcaccgac tatagggtat ggattatgga gctccaatgc tttactttgc
    31081 ctgaaacgaa ttctgcgaat gccttccgga gcttctactt ttcctaaggc cgcaatcctg
    31141 tgctctaggg ttttagcagc attatacatc tttttttcct tacttcctat tgatttttga
    31201 tgagctaaac gccctccgtc ttcagtactt tttttctttg aagaaccttt tgccttctgt
    31261 tctattttac gagcctgttt tcgcttttcc tccgcagccc tttccaatcg ggcacgttcc
    31321 gcaataaatt gttcgtattc tgcagcttgg ctcttacgtt cttcctcttt ctgacgaaga
    31381 taatcagaat agtttcccca atactcagtg attttgccat ctttcagttc ccatatttta
    31441 tctactattt catcaagaaa atagcggtca tggctaataa ctaacagtgc acctgtaaaa
    31501 tattttagct gtcctattag aaaatcaatt ccttcacggt ctaaatggct cgtaggttca
    31561 tccgctaaaa taccatgaac ctgtgccgat aaggcctgtg ctattttaag ccttgtttct
    31621 tcaccaccgc tcatagtctg tatatttaat tgctcaacac ctagcttgcc tacaagtgca
    31681 aaatcttttt cctcctgcag agttacttcg tccaactggg gaatataggc aagttcaccc
    31741 agacgattca ttttacatcc tgggggagtt aattctccta aaagtaccct gagtaaagtg
    31801 ctttttccag caccatttgc tcctactaaa ccaatacggt cataatcata tacttctaat
    31861 tcatttatat ctaaaacatc gcgtcctttg aattccacac gaatgtcttt tgcttttaat
    31921 attaattcca taacatttcc tcctgtctat aatcgcatgc tttcatttgc ttgtatgcag
    31981 ggaaaaccct gcgattttag caggaagagt tacatgaaaa taagatacat aaatattcct
    32041 ccaatattgt ttattttaaa tctaattttc taacctcagt tatcatttgg caaactatag
    32101 caatgccaat aattaaaata cctgatagta aaaaccaatg atttacaccg attttatcag
    32161 caaagaatcc agaaagaatt aacccaattg gcatagcaag tgacatgata cttccgatca
    32221 aagaaaatac acgtcctaaa tattcaggct taattttctc ctgaaaaaga gctgtttgca
    32281 caccgctata aaatggcacc gaaagcccca ttattgcaca gcaaactacg aatattacaa
    32341 atccatttgg aggaagtatt cccgaaacgg ctaaactggt ccccattata aaaaatgaac
    32401 ttgttattag taatacatgc ttttcgaagc cccctaatct tcctaataat aagcctcctg
    32461 ctagcatccc aaatgcaaag gaaatttccg taatagaaat atgcacaggc gttccattaa
    32521 agtgttccat gcttattaaa ggaaatagtg cattgattgg catataaaca aaagtatata
    32581 gtgttcctaa gagtaataag gcaaacaatc ctttgttttg tctcagaacc acaactcctt
    32641 ctttcatctc ccttatgaaa tttggttcta aactttgcac ttgattaccc agcttaggta
    32701 tacgtacaat tgctaccgta atagatgcaa tcacagcacc caatacgtcg atggcaataa
    32761 tagcatttaa atcccaaacg gagtataaga gtgctgcaac tgccggacta acaatatagc
    32821 ttatagactg caaagactga ctatagcctg cgcatttcgt tagctgttct tctggtacta
    32881 aaagtggtgt aaccgcattg agtgctgggg tatgaaaagc tgttccaatg ctacggataa
    32941 acaatactat cataatcatc cagacaggta gctccataca gaatgcaaca atagcaagca
    33001 ctgcaccagc tgctgcgata attaaatcgg caccaatcat tatcttcttc ctatcatgac
    33061 gatccactag cacaccaatg gcaggtccca aaatcgcata gggtaaaaaa cctactaatg
    33121 aagccataga caagaccatc gcagatcctg ttttttctgt aaggtaaaaa ataatcgcca
    33181 tttgcaggat ggcactagtg attaatgata ctgcttgccc tgcccatatt gcataaaatt
    33241 ttcgtttcca attgttgtat ttttccattt atattatctc ctgcatatta ttttgcttga
    33301 atttctattt tgaatagcat tctaggcaat aaaaaatgca ggccaaaccc cacaatgtgg
    33361 cttttggtct gcatacatac aatttggaaa cattcatatt aaagacatag ttaaataaag
    33421 gtatagttaa ataaccaata tcctcaccgt aactaatgaa tgctcaatat cgtataaata
    33481 agcacaacaa aaaagcctat catcgggtat agattctgct ttttttattg ccagcttatc
    33541 ttaaacgcat tgaggctgtc atagtttcgg ttcctcctac atctttgttt atatcaattt
    33601 atagtataac acaacaagat gatatgttca atataaaagt tatggaatga gactcatact
    33661 tccaattcga tgccagattt aaaggatatg acgaagtttt cttcatagac tgtaacgctc
    33721 tggattatct tccttagtag caagcgatta gctttcacaa aatcttctgt ttgtagtttt
    33781 aaaaattcat caggattttc taactcaacc tcaaaatatt tcattttaca ttccctcatt
    33841 tcatttattg ataaattgag tttgcaaaaa agagtggaca atttttgtct actcttaacc
    33901 tttaaaatag ttttttttaa tcgatttgaa gttgcctaaa ttattactta ttcggtaaaa
    33961 tgaagtattg ctttcaacag atttccttca actacacttc acttgattca aacaaggtgg
    34021 gtacatttct attcccacaa actccttgtc aatggaaaca aacacgtacc cacagggtaa
    34081 atggaaatag aaactgataa tttctagcta tcacttctac tcattccaaa aattttctca
    34141 ctctgatact tacccaccat aaagcaaaaa gccttgcaat caaggctttc attatccctt
    34201 tcgttcaaag gtttctaagc ttttacgagc agagcgacac actcagcggt tcgctatctc
    34261 cgttctgtct gcgtgctagc acttgtcaat cacggacagc tatcgcatgg gcggaagtaa
    34321 atgctaatct tcgtcgtttt actccttgac tagcaaactt accgcctcaa catgtcctgt
    34381 atgtggaaat aaaacacgat taaagataag ggaagatact gaattaaaaa aattccccct
    34441 ctattgtccg aaatgcagac aagaaaattt aattgaaata aagcagttca aagtaactgt
    34501 gattacagag ccagacgcaa agacgcagag ccgataaaat gagattaata caatctcatt
    34561 ttatcggctc tttccgttat gtatggattc ttttaattag tcttcgatgt ttcttgcttc
    34621 gttgataccg ctggctaaag attccattaa ggatagttct ttgtctgtaa agctatccat
    34681 gtatttctct atctgtaatc gtcgggtgct ttttaccaag ttattagcag gtaagaaaaa
    34741 ttcatcaacg gaaacatgaa gtaacgatac aaggtcataa agaacttgta tgctggggtg
    34801 ttgcccttta ttttcaatat tagttaagta ccgtgggtca atttcaatca atgctcccac
    34861 ttgttcacga gttaaacctc gtttcaatcg agcttcttta atggctaaac caaaggctct
    34921 aaaatcatat ttatcttctt ttttacgcat agtagaccac ctctatacat tttattgttc
    34981 ctactgaatt aaaaacaggt atagaaaaac gtgttatatg gtttataggt ttatatttaa
    35041 taaaaagcac tactaaacgc caataaaaaa aaccgttata tggtagtgct atttacgctg
    35101 ttaaaatatt gtatattact tccaaatggc ggtttgttgg aggtcaacgt cgccatgaag
    35161 tacatcatat acaataaatt tccttacatt gggttcttgt caaaaaaagt cgtctatctg
    35221 caatagataa gtacgtccac caatgtggtt ttataaatca tatagataga ataacagaag
    35281 catgtaaaca gagaaataaa tctgtttata tgcttttttg gctattcaga acttttttac
    35341 aaagtttatt tatcagtaat gcaacaaatc cccctttcac attgggacta agagtgaaag
    35401 gagataaacg agcaaggctc acttcctttc ctagacagaa agggggtgag aaacatgaaa
    35461 ccatcttctt ttcagaccac aatagaaaat cagtttgact atatctgtaa acgtgctatg
    35521 gaagacgagc gaaagaatta tatgctttat ctttcaagga ttgcaaagcg tgaggtgtcc
    35581 ttttcggatg ttggcgatta tcttgttagc cagtttgcga caacagataa ctattcaact
    35641 gactttcaga tttttacact caatgggtta tcagtaggcg ttgaaaatga tttgttgagt
    35701 gaagcattac gtgagttgcc agacaagaaa cgtgaaattc tactgctgtt ttactttatg
    35761 gacatgagcg attcagaaat tgcagacctg ttgaaattga accgttctac tgtctatcgg
    35821 catagaacca gtggactagc cttaattaaa aagtttatgg aggaatttga agaatgaaaa
    35881 cacaatatcc tatgattccc tttcctctca ttgtaaaggc aacagatggc gataccgaag
    35941 cgattaacca gattctacat cattacagag ggtacataac gaagcgttcc ctacgactta
    36001 tgaaagatga atatggcaat caaagtatgg tcgttgatga agtcttacgt ggaagaatgg
    36061 aaaccagact gattacaaag attttgtcat ttgaaattaa gtaatatcct ctctcctttc
    36121 gtggaagcgt gctaaaccat tccacgcttc ccgaacaggg aggtttgtta ttccaccaaa
    36181 gcatattgag ctttcaatgt gttttgatag gctaacgagc cattgttctt tgaaaactga
    36241 ataaaagtaa tcgaatacgt ttcgataaga aaagagccaa cggaactaac cgccatgacc
    36301 tatcttataa agatagcgag cgattcatgt tagtgatccg agaagcaatc tttagcagga
    36361 ttgcctgcaa cgacattctt atcgtgataa tgatactccc atacagtcaa tagtccgagc
    36421 gtgataaaac cgtcgcaggc aatgagtatg gctacatgag aaccatgcag gggtggaact
    36481 cccgtgagct ttgctaaagc tgttcgattg ctggtaaaac aacttttatg aaatccaaat
    36541 aagtgatttg gaaaggagga ttttatgaag cagactgaca ttcctatttg ggaacgttat
    36601 accctaacca ttgaagaagc gtcaaaatat tttcgtattg gcgaaaacaa gctacgacgc
    36661 ttggcagagg aaaataaaaa tgcaaattgg ctgattatga atggcaatcg tattcagatt
    36721 aaacgaaaac aatttgaaaa aattatagat acattggacg caatctagcg tcgccaaagg
    36781 gtcttgtata tgataaaata gtattaagtc gtatcaaggc tctttccata aaggaaagga
    36841 gcaaatgcca tgtcagaaaa aagacgtgac aataaaggtc gaatcttaaa gactggagag
    36901 agccaacgaa aagacggaag atacttatac aaatatatag attcatttgg agaaccgcaa
    36961 tttgtttact cgtggaaact tgtggctaca gaccgagtac cagcaggaaa gcgtgattgt
    37021 atctcactta gagagaaaat cgcagagtta cagaaagaca ttcatgatgg tattgatgtt
    37081 gtaggaaaga aaatgacact ctgccagctt tacgcaaaac agaacgctca aagaccaaag
    37141 gttagaaaaa acactgaaac tggacgcaaa tatcttatgg atattttgaa gaaagacaag
    37201 ttaggtgtaa gaagtattga cagtattaag ccatcagacg ctaaagaatg ggctattaga
    37261 atgagtgaaa atggttatgc ttatcaaacc atcaataact acaaacgttc tttaaaggct
    37321 tcattctata ttgctataca agatgattgt gttcggaaga atccatttga ctttcaactg
    37381 aaagcagttc ttgatgatga tactgtccct aagaccgtac taacagaaga acaggaagaa
    37441 aaactgttag cctttgcaaa agctgataaa acctacagca aaaattatga tgaaattctg
    37501 atactcttaa aaacaggtct tcgtatttca gagtttggtg gtttgacact tccagattta
    37561 gattttgaga atcgtcttgt caatatagac catcagctat tgagagatac tgaaattggg
    37621 tactacattg aaacaccaaa gaccaaaagt ggcgaacgtc aagttcctat ggttgaagaa
    37681 gcctatcaag catttaagcg agtgttagcg aatcgaaaga atgataagcg tgttgagatt
    37741 gatggatata gtgatttcct ctttcttaat agaaagaact atccaaaagt ggcaagtgat
    37801 tacaacggca tgatgaaagg tcttgttaag aaatacaata agtataacga ggataaattg
    37861 ccacacatca ctccacatag tttgcgacat acattctgta ccaactatgc aaatgcagga
    37921 atgaatccaa aggcattaca gtacattatg ggacatgcta atatagccat gacgctgaac
    37981 tattacgcac atgcaacatt cgattctgca atggcagaaa tgaaacgctt gaataaagag
    38041 aagcaacagg agcgtcttgt tgcttagtag tacaaatgaa tttactactt atttaccact
    38101 tctgacagct aagacatgag gaaatatgca aagaaacgtg aagtatcttc ctacagtaaa
    38161 aatactcgaa agcacataga ataaggcttt acgagcattt aagaaaatat aaaaagataa
    38221 ttagaaattt atactttgtt tattttaaag aagtgattct aatgtacaag ggtgtaattt
    38281 gttagaattt caaaaattta gagcattttt ggcttagtaa tatgtgttga aggctcaaaa
    38341 tctatggtaa aaaagtagct ttgaaaacgt attacctcca aagatttagt ttaataatga
    38401 attaacataa aaagaaatga ttgaagttct ggaaagatgt tgtttcagta ttgaaatcat
    38461 tgagaaaaag tgggaaaaat ttgcgatttt cacagagaaa ggaagaaaaa gtatagaaat
    38521 aagtcaaatg gagatgtttg ataaaatgct ttcatagcta accaactgtt gaaaattatg
    38581 agttacaaaa tctaaagtat ttaagattag tttataaaat taggtctctg cctgtagaaa
    38641 ggaacgtgca gttagaaagg aggaaaaaat aggatactat aattcagact gagatttcta
    38701 attaaaatat gtagttgcat catcccttgc cgttttggca tttagtttgg ctcttcctgt
    38761 tttggtagct tctcaccgtg gtggcgagtg gacctatgga ggctatcatg atccaaataa
    38821 ttggggagca aattacattt gatgcgggat ggtaaagaat aattgaagaa gattctttta
    38881 tcaatagttt agtaagcttg ttagtttata gaggtcaggg gtatttctgc cctctgtttt
    38941 agaataagga atgcactatg aaaaaattat ttatactcat atccaacctg cttgctagtt
    39001 tgttctttgt ttgggtattt accatttgga ctgatacata tgtctcctat tattacccca
    39061 acgttgttgt acgtgattct tcccctgaaa caacttttca gcatgttgct acacgcttgg
    39121 aaaaactagc agaagaaacg gatagcttta ttgcgattca acaccaagat cctaactcag
    39181 aaggtactcc agtgttttct tatacgacct ttgggaacgg aaagttgcct gatgggcttc
    39241 aggaaaaaaa tctagaagat gctcaaagta gtagtgttga aacaaactat tttgtattcg
    39301 atggaaacct agatattcac ttgctaaggg aggagctaag tcaacttggc ttgactaaca
    39361 tgcacctgac aattccatct aaactatcta cgttaatggc tatctttagt aacggatttc
    39421 agttaatcag tctattgatt ttcatcttaa cctttggagc actaacttta attagtcaaa
    39481 ttagccaatt acggtcgtcg ggcattcgcc tcatttcagg agagaaacgg tggttcattt
    39541 ttcttagacc agttggtgag gatttgaaag ggatagctgt tggtttcagt ttagctggcg
    39601 tgctcaccat tcttatgcaa aaaattctgt cgcttccaac gcaatcccta atgaccatag
    39661 gagcaggctt gctcagttat aatctcatct tgttgtcgat ctccctgttt ttcgctcaac
    39721 tcttcgcagt tgggataaaa aagatacacc tgatgcagat tataaaaggg caagtgcctg
    39781 tcagaggaat cattagtttg attttaatcg gtcaactatt agcgattatt attgtaacgc
    39841 tgggaatagg gagtagctta aagtattccc aagcctggca acagcatcgg attggacaag
    39901 aggcttggag ccaggaaagg caactgatta ccctatcaat cagccgtgaa ggaacgagtc
    39961 ctggttttga tgaacaagct caaaggaaac tcagaacttg gtatcaattg atggatctgg
    40021 ctgtttcaga acaaaaggct ttcttatcta gacaccagtt aattgaccgt actttgcaaa
    40081 atggtatggc ttcctccaaa aactttataa cctctacaga atggtacgat tacagcccga
    40141 atggcaatgt ccttatcgtc acaccgcaat acttggagcg tcaaaacatt cctgtagata
    40201 caactattga gcaaaagatg aatcaccttg atgtagggga gtttgtctta ttgctgcctg
    40261 aacacctccg ttcagaggaa gatcattata aatctgtttt tgaagacgac ttaaccagtc
    40321 gcatgtctag tcaagatgaa cgacagcaaa tgactgctac ggtaggttat ttagaatcag
    40381 gtcaggatcg ttttgtgtat aatacgaccc ctatttctta ccagcagttt ttgaaagatc
    40441 caatcatcat tgttataaca ccccaatcaa ctggtccaca gtccattttg ttttggatag
    40501 acgcagtaca gaactacgtt ctctttaatc aattgtctga tgcccaggag cttatccaga
    40561 gacaaggcat tgaaaattgg gtctcagaaa tgcaaacagg ttaccacaac tacatcacat
    40621 tattggataa tatccagagg gaacgttggg taatgctagc aggagctgtg cttgggattg
    40681 caacttcaat cttgttgttt aacactatga ataggctcta ctttgaagaa tttagacgtg
    40741 ccatttttat caaacgcatt gcaggtctca ggttcttaga aatccatcgc acttatctct
    40801 ttgctcaact gggtgtgttt ttactgggat ttgttgcgag tgtatttctt caggtagaga
    40861 taggagttgc tttcttagtc ttgttactct ttactggtct atctctttta cagttacatg
    40921 tccaaatgca gaaagaaaac aagatgtcca ttcttgtttt gaagggaggt taatatgatt
    40981 gaacttaaac aggtgagtaa atcttttgga gaacgagagt tattttcgaa tctttcaatg
    41041 acatttgagg ctggaaaagt ctatgcctta attggttcaa gtggtagcgg aaaaacaacc
    41101 ttgatgaaca tgattgggaa attagaacct tatgatggga cgatttttta ccgaggtaaa
    41161 gacttggcca attataaatc gagtgatttt ttccgtcacg aattgggtta cctcttccag
    41221 aactttggct taattgaaaa ccaaagtatt gaagaaaacc ttaagctagg tctcactggt
    41281 caaaagttga gtcggtcgga acagcggttg aggcagaagc aggctttaga acaggtcggc
    41341 ctggcttatc ttgacctaga taagcgcatc tttgagttat cgggcggaga atcgcaacgg
    41401 gttgccttgg caaaagttat cttaaagaat ccacccttta ttctggcaga tgagccaaca
    41461 gcttcaatag acccagcaac ctctcagttg attatggaga ttttgctatc tcttcgagat
    41521 gataataggc taatcattat cgcaacacat aatccggcaa tttgggagat ggctgatgaa
    41581 gtgttcacga tggatcatct gaaataaaaa tccttgtttt taattgcacg atgagttact
    41641 gaaatattat catgaatcaa gaattggagt taatttagaa ttgtacttta ttaatattga
    41701 ggtaactttt tcttgataaa ggaagaaata atggagagga agttagaatg aaaaaattcg
    41761 acaattatat tattgagaag ccttgcgatt ctaattcaga taaactgcaa aaaatcttaa
    41821 taattgaaag tttggtagat gatattttgc aattttctct cagaatcaat aatagtgtag
    41881 gagagatttt cctcctacaa ccgttttaaa agaaaactat ctttattcca tgttattttg
    41941 aggaagatat tgtgaaagtc aaagatgatg ataaagttga gtggaatttg ttagaatttc
    42001 aaaaatttag agcatttttg gcttagtaat ctgtgttgaa ggctcaaaac ctatggtaaa
    42061 aaagtagctt tgaaaacgta ttgcctccaa agatttagtt aaataatgat ttaacacaaa
    42121 aagaaattat tgaagttctg gaaagatgtt gtttcagtat tgagaaaagg tgggaaaaac
    42181 ttgcgatttt cacagagaaa ggaagaaaaa gtatagaaat atagtcaatt gaaacaagaa
    42241 caggataaaa gaaccttttg tgccatattt ttctcctttc gctttacaat tggattgaac
    42301 acctttattg tatcgcgttt ggagtttttt tggtataacc ttcgacgcgc acccgcatag
    42361 cgggtgtttt tttgtctcgc acctaacgga gcgagacaaa ctaatagtca cttaatcaaa
    42421 aaacgcacca tatcaaaaac taaaaagttt gatatcatgc gtcatgtctt aaactaattg
    42481 actatacttt ctattcaaat gagcttttaa ccaattgatt gagccaatcc actcttaaaa
    42541 ccaaagagca atttctcgct tagctgactc ttctgaatct gaaccatgta caacattttg
    42601 gataatctca ttttctccag cagcttttgc aaaatcacct cgaatagtgc ctggtaaagc
    42661 ttcttctgga cgagttgcac ccatcatggt ccgccaagtt tcgattactt tgggaccaga
    42721 aatgacaccc acaagaactg gacctgaagt catgaattca cgaatcggtg ggtaaaaact
    42781 ctgaccaacc aagtcctgat agtgctggtc aatcaactct tctgaaacct gtgaacgaaa
    42841 ctccaatttt tcgattgtaa atccacgttg ttcgatgcgc tttaacactt cacccactag
    42901 ccctcttttt acaccatctg gtttgatgat aaagaatgtt tgttccatac ccgtctcctt
    42961 tgtcagcttc tttcttttat tttaccacat ttcgtggaaa aatggagaaa gttttcagaa
    43021 gagagaatga gagaaccctc gggttctctc attctctctt attctactgt ttcttccaca
    43081 gtttcaacgg cagtatccac aactacttct gttgtttctt catttccttc ttcctctact
    43141 ggaggattaa ggtattcttc ttcgttgaca gcatgtggtt caaggttacg gtaacgggcc
    43201 ataccagtac cagctgggat gatcttaccg atgataacat tttctttaag tccaaggaga
    43261 tggtctttct taccacggat agctgcgtca gtaaggacac gagttgtttc ctggaaggaa
    43321 gccgctgaca agaaactgtt tgtttcaagt gaggctttgg taattcccat aaggactggg
    43381 cgacctgtcg ctggaactcc acctgcgata aggacatctt tgttggcatc tgtaaagtca
    43441 ttgatatcca tgagggtacc catgagaaga tctgtatcac ctggatccat gacacggact
    43501 ttacggatca tttgacgaac cattacctcg atgtgtttgt caccgatttc taccccttgg
    43561 ctacggtaaa ctttttgtac ttcaccgaga aggtacgttt caactgacaa gacatcacga
    43621 actgcaagga gacgttttgg ttggatagaa ccttctgtca gagcagcacc acgcgctact
    43681 tggcccccaa cttcgacacg catacgagct gtaaatggaa cgacatattc accttcgcca
    43741 gtttcaccct taacaaagac tttcttggta cgagttgatg catcttcttc gatagcagta
    43801 acttgtcctt taacctctgt tataaccgct tcccctttag gattgcgggc ttcaaagatt
    43861 tcttggacac gaggaagacc ctgagtgata tcggtatttg aggcaacccc acctgtgtgg
    43921 aaggtacgca ttgtaagctg tgtaccaggt tccccgatag attgggcagc gattgtacca
    43981 actgcttcac caacttcaac cgcatcacca gtcgccaagt tgataccata acagtgacgg
    44041 cagacaccgt gacgagtgtt acatgtaaat acagaacgga tagtcacttc ttccacacca
    44101 gcattgacaa tttcacgcgc cttgtcttct gtaatcaatt catttggacc aataatcact
    44161 gcaccagttt ctggatgttt aacagttttc ttagtgtaac gaccgttgag acgctcttcg
    44221 agagactcga tcatctcttt tccttctgcg atagaacgga tcaagagacc acggtcagtt
    44281 ccacagtcgt cctcacggat gataacgtct tgggcaacgt cgaccaaacg acgagtcaag
    44341 taacctgagt cggctgtctt aagggccgta tcggtcatac ctttacgagc accgtgagtt
    44401 gagaagaaca tttccaatac cgacaaacct tcgcggaagt ttgaaagaat tggcaattcc
    44461 atgatacgtc cattcggagc agccatcaga ccacgcatac cggcaagctg tgagaagttt
    44521 gagatgttac cacgggctcc agagtccatc atcataacga ttgggttctt aggatcttgg
    44581 ttagcaatca agcgtttctc aagtttttca cgggcagcac gccattcagc tgtaacagca
    44641 ttgtaacgct cgtcgtctgt gatcatacca cgacggaatt gtttggtgat ttgttcgaca
    44701 cgtttgtgtg attcttcaat gatttcagcc ttgtcatcaa cgactgggat gtcggcaata
    44761 cccactgtca atcctgcaag agttgagtgg tggtaaccga gattcttcat gcggtcaagt
    44821 agggcagaag tttctgtcgt acggaaacgt ttgaagattt cagcgatgat atttccaagg
    44881 ttttttttct tgaatggagg gttgagctca agattgctga tagcttcctt gatatctcca
    44941 ccaagtggca agaagtattt agctggaaca ccttctgtca agttggcatt gtttggttct
    45001 tgcaagtatg gtagcccctc tggcatgata tcgttgaaga gaattttacc aactgttgta
    45061 agcaagacct tatgtctttg ctcttctgtc caaggcttgt tgaggctgtc tgttgcgata
    45121 ccaacacgtg agtggaggtg aacatagcca ttgcggtaag ccataaccgc ttcgtcacgg
    45181 tctttgaaga ccattccttc accttcgcga ccagcttctt ccatggtcaa gtagtagtta
    45241 cccaaaacca tgtcctgaga tggagtaact accggtttcc catctttcgg gttcaagatg
    45301 tgctcagcag ctagcatgag gatacgagct tctgcttgtg cttcttctga aagtggtacg
    45361 tggatggcca tttggtcccc gtcaaagtca gcattgtagg cttcacagac aagtgggtgc
    45421 aagcgaagag ccttaccatc aatcaagact ggctcgaagg cttggatacc caaacggtga
    45481 agggtcggtg cgcggttcaa aagcactggg tgttctttaa tcacttcttc aaggatatcc
    45541 cagatacgct catctccgcg ttccaccaag cgtttagctg ctttgacgtt ttgcacgata
    45601 tcacgggcaa cgatttcacg catgacaaat ggtttaaaga gttcaatcgc catttcacgt
    45661 ggcacaccac attggtacat cttaagagtt ggaccaacag cgataacgga acgtcctgaa
    45721 aagtcaacac gtttaccgag caagttttga cggaagcgtc cttgtttacc tttaagcatg
    45781 tggctcaatg atttcaatgg acggctacct ggtcctgtga ttggacgacc acggcgacca
    45841 ttgtcaatca aagcgtcaac tgcttcttga agcatacgct tctcattttg aacgatgata
    45901 cctggtgcat ttaactcaag caaacgagcc aaacggttgt tacggttgat aacacggcgg
    45961 taaaggtcat tcaagtcaga tgaggcaaaa cggccaccat ccaactgcaa cattggacga
    46021 agatctggtg gaataaccgg aaggatgtta agaatcatcc attcaggttt gtttccagac
    46081 ttgtaaaagg catccaaaac atccaaacga cggatggctt tgacacgttt ttgtccagta
    46141 gctgttttca attcttcttt gagttcagca atttcttttt caagatctac ttgcttcaaa
    46201 aggtcttgga tggcttccgc acccatcttg gcaacaaatg aaccataacc atattcacgc
    46261 aagcgctctc ggtattcgcg ctctgtcatg atagacttgt gctcaagtgg tgtatcctta
    46321 ggatcaatca ccacataagc cgcaaagtag ataacttcct cgagggcacg agggctcata
    46381 tcaagggtca agcccatacg gcttggaatc cccttgaagt accagatgtg agatacagga
    46441 gctttcaatt cgatatgtcc catacgctca cgacgaactt tcgtacgcgt tacttcaacc
    46501 ccacagcggt cacaaacaat tcctctgtaa cgaatgcgtt tgtacttacc acaagcacat
    46561 tcccagtctt ttgtaggacc aaagatcact tcatcaaaga gtccttcacg ttctggtttc
    46621 aaggtacggt aattgattgt ttcaggtttt ttgacttctc cataagacca tgaacggact
    46681 ttacttggag aagctagggt gatttgcata cttttaaaac gatttacatc aaccactatt
    46741 tcttcccttt ctattctaag tgaactgctt attcttgttc agcagcttct tctgttgctt
    46801 ccgcttttgt tgctttctca gcttcttcag cttcaaaggc tgctttagcc tcttgggctg
    46861 ctttttcgcg ggctttttca aggtcatcta cgtggatgac atcttcgtcc attccttcat
    46921 ccaagtcgcg aagttccact tcttggtcat cttcgtctag gacacgcatg tcaagaccaa
    46981 gagattgcaa ttctttgaca agaactcgga aggattctgg aacacctggt tttggaattg
    47041 gtttgccttt tgtaatagct tcataggctt tcaaacgtcc gttgatatcg tcagacttgt
    47101 aagtcaagat ttcttgaagg acatttgacg caccgtaggc ttcaagagcc caaacctcca
    47161 tctcaccgaa acgttgtcca ccaaactgag ctttacctcc gagtggttgt tgggtaacag
    47221 ttgagtaagg tccgactgaa cgcgcgtgca atttatcgtc aaccatgtgg tggagtttga
    47281 tcatgtacat gactccaaca gaaacacggt tatcaaatgg ttcaccagta cgtccatcgt
    47341 aaaggatcgt tttggcatcg ctatccatac ctgcttcttt aacagttgac caaagatctt
    47401 cagaacttgc tccatcaaag actggtgtcg caatgtgaat accaagagta cgagctgcca
    47461 taccaaggtg aagctccata acctgaccga tattcatacg tgatggcacc ccaagtgggt
    47521 tcaacatgat gtcgactgga gttccgtctg gaaggtaagg catgtcttct acaggaacga
    47581 tacgagagac aacccctttg tttccgtgac gtccggccat tttatctccg accttaatct
    47641 tacgtttttg agcgatgtaa acacgaacca acatgttaac acctgattgc aactcatctc
    47701 catttacacg tgtaaagatc ttaacatcac gaacgacacc atcggcaccg tgtggtacac
    47761 gaagagaagt atcacgcact tcacgagact tgtctccaaa gatagcgtgc aagagacgtt
    47821 cttcagctga aagatctttc tcacccttag gtgttacttt acctacaaga atatcacctt
    47881 ctttaacctc agcaccaata cggataatcc ccatttcgtc aaggtctttg agggcatctt
    47941 caccaacgtt tggaatttcg cgagtgattt cttcaggccc aagctttgta tcgcgcgttt
    48001 ctgattcgta ttcttcaagg tgaacagatg tgtagacatc gtccttcacc aagcgttcgc
    48061 tcatgataac ggcatcctcg aagttgtaac cttcccaagt catgtaggca acgattgggt
    48121 tttgtccaag cgccatttct ccattttcca tagaaggtcc gtcagcgatg aaatcgcctt
    48181 tttcaacgac atcaccaact tttacgagag tgcgttggtt gtaagcagta cctgagtttg
    48241 aacgacggaa tttttggatg tggtaaacat ccaatgatcc atcttcacga cgaacttcta
    48301 ccttgtcagc atctgcgtaa gtaactttac catcatactg agcaatcaca gccgcaccag
    48361 aatcgtgggc tgcttggtat tccataccag taccaacgta aggtgcctga ggattaatca
    48421 atggcacagc ctgacgttgc atattggctc ccatgagggc acggttggag tcatcgtttt
    48481 ccaagaaagg aatacatgct gtcgcaacgg caactacctg ttttggtgaa acgtccatgt
    48541 agtcaacaat attagctgga tactcttggt tgaccccttg gtgacgtccc atgacaatct
    48601 tctcagcaaa ggttccatct tcattcagac gagagttagc ctgagctaca gtatattcat
    48661 cttcttcatc agctgtcaac caaacaattt cgttcgtgac aacacctgtt tcacggtcaa
    48721 ccttacggta tggtgtttga acaaaaccat atttgttcaa gtgtccgtaa gatgacaagt
    48781 tattgatcaa accgatgtta ggtccttcag gtgtctcgat tggacacata cgaccatagt
    48841 gagtgtagtg cacgtcacgt acttcatatc cagcacggtc acgagtcaaa ccaccaggtc
    48901 ctaaggctga caaacggcgt ttgtgagaca actcagaaag cgggttgtgt tggtccatga
    48961 actgtgacaa ctgtgatgaa ccaaagaatt ctttaactgc agctgttaca ggacggatat
    49021 tgataatttg ttgtggtgtc aagacttcat tgtcctgaac agacatacgt tcacggacat
    49081 tacgttccat acgagaaagt cccaaacgta cttggttggc aagcaattca ccaaccgcac
    49141 ggatacgacg atttccaagg tggtcgatat catctacacg gccaagtcct tcagccaagt
    49201 tgaggaagta gctcatctca gcaaggatat ctgcaggagt caccgtacga accttgtcat
    49261 ctgggttagc attaccaatg atcgttacga cgcgatctgg atcagttgga gcaacaacct
    49321 tgaatttttg aagaacaaca ggctcagtca caacggctgc atcgtttggg atgtagacaa
    49381 tcttgttcaa gtcgccatcc aaatggcttt caatgctttc aatcacgcta cgagtcataa
    49441 tcgtaccagc ttctaccaag atttctccag tttcagggtc taccaatggc tctgcaatgg
    49501 tttggttgag caaacgtgtt ttaacattga gttttttatt gattttgtaa cgaccaactg
    49561 ctgccaagtc atagcgacgt gggtcaaaga agcgagccac aagcaagcta cgtgagcttt
    49621 cagctgtctt aggctcacct ggacgaaggc gttcgtaaat ttctttcaag gcttcgtctg
    49681 tacgagagtc cattggattt ttgtggatat ctttttcaac agtgttgcga accaattcgc
    49741 tgtcaccaaa gatatcaaag atttcatcat cacctgagaa accaagagca cgaaccaagg
    49801 ttgtaaatgg aatcttacga gtacggtcga tacgagtgta ggtgatatct tttgagtcgc
    49861 tttcaagttc caaccaagct ccacggttag ggataacagt tgaaccatag cccaccttac
    49921 catttttgtc tactttgtcg ttaaagtaaa cacctggtga gcggaccaac tgagaaacga
    49981 taatacgttc accaccattg atgatgaaag tacccatttc tgtcatgatt gggaaatcac
    50041 caaagaaaac ttcttgggtc ttgatttcgc ctgtttcttt attgatcaaa cggaaggtta
    50101 caaaaattgg tgctgagtag ctagcatcgt ggatacgagc ttcttctagc gtgtattttg
    50161 gttccttgat ttcatatcca acaaattcca actccattgt gtctgtgaag tttgaaattg
    50221 gcaatacatc ttcaaacact tccttaagac cgtggtctag gaaagctttg aatgagtcag
    50281 tttgaatttc aatcaaattt ggtaagtcaa gaacttcttt gattcttgaa aaactacgac
    50341 gggtacgatg tttcccgtat tgaacgtcat gtcctgccaa gatgattctc ctttgtaaat
    50401 aagttccaag ccttgtcaat caggcttttc taatcgtcat atggttgtaa accccttatc
    50461 accgtgtcct tttgacgaat tttcagaatc tttaagcctc tgttacaaat gctcaaaatc
    50521 ttgaaaaaaa gcacaaaaag agcagctaaa tctgactttt tcagaagatt taactgctgt
    50581 gagccttgtc tggacaatat ttcagacaaa acctacgaca aatgattacc catattatac
    50641 cctatttagc tagatttttc aaggggtttc agtaggtttt tggtaaattt tttcccatag
    50701 aaaacttggc atcacattcg aatcacgcta tggtacaaaa aactgaaaaa actattgact
    50761 gaaaatcatt ttcaaggtat aataataaac gttaaggcgg tatagccaag tggtaaggca
    50821 cggctctgca aaagcttgat cgtcggttca aatccgtcta ccgccttcta taacttgatt
    50881 tatcaggttt caaatgaaca gaaagcccaa tttgaagggc ttttcttatt ttccctcgaa
    50941 taaatacgta taactttaaa aacttttgga gcgagtttgt ggcagagttc tttccatggc
    51001 ataattccct tttgaaatca attgaaaaaa gcttcgtcac gcctggtgac aaaagcctct
    51061 agtttattct gtttcttctt ctatttcgac ttctgtgatt tggactttta ccttggtaac
    51121 acgtccattc ttcactttat cattggttaa gataaactgt ttgttttggc tgaccaattc
    51181 atagctgagt ttctcagtcg ttggaatagt tcccactcct gtcaaataat aaccagcgat
    51241 ggtatcaacg tcatcacttt ccagttcaac atcaaagtaa ttattgaaat cattgagggt
    51301 catagttcct tgaacaatgt aggtatcctc gccaatctga tgaacatcta ttgctgcttt
    51361 gtccgtttca tcatcaattt caccaacaat ttcctctaag aggtcttcca aagtcaccaa
    51421 accagccata ccaccgtatt catccagcaa gattgccatt tgtctttggg tatttcgcag
    51481 ttcttttagc aagtcatcca caaaaatagt ttcaggtaca aaaagtggat cttgtaaaat
    51541 tctcttccaa acaatattgt caaaaccgtc cacaaagcct gccttaagga gactcttggt
    51601 gtgaatgatt ccaattacat tgtccttatc cccatcataa accgggatac gagaataatt
    51661 ttgttttaaa atactttgga taatggcttg actatcatcc tgaatatcca ccataaaggc
    51721 atccgttcga ggcaccataa cctctcgtgc catcagttca tcgagcgaaa agacaccttg
    51781 tagcatctca atctcatcag catccaatgt ttcttcacta tttgtcagca tataggcaat
    51841 ttcatcacgg gtcatctttt catccgcatc atcgaatgac ataggagtca aatggctcaa
    51901 gaaattggtc gaagcagcta aaagccaaac aaaaggactg actagttttc cgatcccaat
    51961 gataatcggc gctgtacgaa ttgccaaggc atcctttaga ttaagagcga ttctcttagg
    52021 atataattcc ccaaaaacga tggaaatata ggtcaaaaat gccaaggata gaaaagttgc
    52081 cacggcttgt gctgtttcgc cattcccaag ccaagaggca atcacacgtc ctagagtatc
    52141 agttaaactc gcccctgata agattgtaat cagggtgatt cctacctgaa tggttgataa
    52201 aaagtggtta ggattttcta gtaccttcag caggcggatg tagcgtctgt ctccttcttc
    52261 cgccttttgt tcaactcggg cacgattaag agaaaccatg gccatttctg tggctgagaa
    52321 aaaggcattt aataccgtca agataaacaa taaaacaaat tgtagcaaca aattctgact
    52381 acttgggtct tccatagttc ttctcctaaa atagtatctt atcctttatt atatcacaaa
    52441 atttaatcca atacatatta tttttttctt agcgtaactt ccatctctct cccaaaactg
    52501 gaagttagtc taagacggat ttccactgat ttcacgcgtt tttctcatac taaaagctag
    52561 gttgtgggaa actggaagtt agttttagaa gttactattt tttcttagta cctattctag
    52621 ccctgcttaa actagtaaaa agaactccta catccataag tgacatagga gtttaggctt
    52681 atcttttact gagttacagt tacttctcca gttcggtaat ccagttgaag tcccttttga
    52741 acattgggaa ctagaacatt gaattccaat tctccatccg aagacttggc ttcaatctgt
    52801 gaagctgagg gaactaaatc ctcgtttgaa gcgtagtaaa gggttacacg gtaacggaca
    52861 cgcttgtttt ggtccaaggc tttacgcacc ttgctttcat agtagttttg accagtcgaa
    52921 tactcggctt gtgcctgatt tgcccaggct gtctgaacag caatgttttt aggattgctt
    52981 gttgaggcat caaaaccatc caaaccaccg attaaggcat agcctaacaa atgacctcta
    53041 tcgactgcat gggtataaga gccctttaga ttcttgacct gatgccaacc tggaggagtc
    53101 caagaagttg aaccattccc agtttcttta cgattcttgt actgacgagt ggcattagac
    53161 aagagggcat tagctacggt tggaacagtt tccttgccca ctgtctttgt tttattgtca
    53221 gcgtagggct tacttgaaac cttggcatct agatttgttt tattaccatt gacgataaaa
    53281 gcacctgagc cattccactc cagactcccc tttatttgac tcttgactgc gtctgttaag
    53341 acactctctg ccaatgcttg actaggagct tcaggcgctt gttttttctg actaagattg
    53401 gttttgggac tattaggtgc cgactgcatc tgcttgatat aatagctccc tgtagacaaa
    53461 agcaataaca ctagcagtcc gattagtgtc tgtcttgttt ttttgttcat atttctcctt
    53521 atctttagaa aaaggctggt tctccagcct aatttcctgt aaatttatga atcaattcct
    53581 gccattttgc tggagacagg atagcccatg gatcttgacc cttgcccaag attccataac
    53641 ctaccattag accgattcct agagccagag tacctaaaat cagtactatg atgactaaaa
    53701 gtaaacgctt gactacgtag cttgatttct tattcatctt catcacttgc ctcaatccgc
    53761 tgaatcttag cacctagctg agccaacttc tcatggaaac cgtagtaacc tctatccaag
    53821 tgaaccaatt taccgaccac agtttctccc tgtgctacca aacctgtcaa aatcaaggct
    53881 gcactggcac gaaggtcagt tgaaagaact tctgctccct gcaaaggctg tccaccaaca
    53941 atacgagctg tatcacggat aatctcagaa tgcaagccca tgcggcgcat ctcttctagg
    54001 tgttggaaac gattttcgaa aactgtctcc accatggttg attcgccttt tgcaactgtc
    54061 atcaaggctg taaattgagc ctgcatatct gttggaaatc ctgggtgggg caaggttttc
    54121 acatgaacag cttttagatt ttctagttga gaacgaacac gaattccttc gtcttcttca
    54181 attacttcaa cacccatttc aagtaacttg gcaatcaagg gacggttgtg ctcccagaca
    54241 gcgtctcgaa tcaagacatc accaccagtc atggcagcag ctaccataaa ggttcctgct
    54301 tcgatacggt cctggactac attgtgagtc gtaccatgaa gtttctcaac accagtaatg
    54361 gttatagtct ctgtaccagc acctttgacc ttggctccca tttcattaag gagaatggct
    54421 aagtcaacaa tctcaggctc acgcgcagca ttctcaatca ctgtcacccc atcagccaga
    54481 gtcgctgcca tcatcaagtt ctgcgttgca ccaacacttg gaaagtccat atagatatga
    54541 gcaccatgca agcgttctgc ctttgcttcg atgtaaccag ctgtctgact aatcttaacc
    54601 cccatagctt ccagaccttt caaatgaaga tcaataggac ggctaccaat cgtacaacca
    54661 cctggcatgg ataccttggc atgacccaca cgggcaagga ttggccctaa tacaacgatg
    54721 gaggcgcgca tcttactgac atacttgtaa ggggcttcct cagtgatgtc gccagtagca
    54781 tccaccttga caagatgagc ttcctcatca aagtcaacct tggcattcaa accaccaact
    54841 acctgattca taataaagac atccgacaaa atcggaacat tctgcaagac ggtctttcct
    54901 tcacttgcta gaatagtcgc tgccaacaag ggtaagactg cattttttgc tccctcgatc
    54961 gtcacgcttc ctaccagacg attatcgcca ccttgaacca caattttatc catactcgtt
    55021 tcctttactc ttgattttat aataatcctc taagcgcttc ttgccacaaa tgatacaggc
    55081 taataaagaa agaactcagg atgtagccta tgacaatgct aaaaaaggct actaataaac
    55141 gaacttttct tgtattctca tctgtcactt ttaaaacctt ctcccatcta acaagatcct
    55201 ttaaaaggta aaaactcaca taaataaaga gcatatgact acttagagtg aataataatt
    55261 gaatcatttg actattatac catcttctct gtttgtgcgc tagtttggaa acttcactca
    55321 aaaattaggg attgtttttc aagtaatcaa tcgcatcttg tagggtttta acgggcacga
    55381 ttttcatatc cgtcttgatt gttttagccg cttctagggc tgtttggtag ttgtttttcg
    55441 cgtccggatg cgccttttgt tcttcttcgc taacagggtt atcaggagta aagaaaatag
    55501 cagcacctgc cctagccgaa gctacaacct tcttatcaat acctccaatg tctcccacat
    55561 taccatcgcg gtcaatggta cctgtaccgg caacaatacg accattacga agatctgggt
    55621 gagctatttg agtatagata gctagactaa acatgagacc agcacttgga ccgccaatac
    55681 cagctgttga aaagctaatt gggacattgc tgattacctc tgtacggtca atcaagccga
    55741 ttccaattcc atttttgcca ttttccaagg tgatgatttt tccttctgca gacttggttt
    55801 gcccatcctc ttcataggtg accttgacgg aatcccctaa tttttgagaa ctgacgtaat
    55861 caatcaagtc tttggaacta tcaaaggtct gatcattgac tgctgtgact gtatcagaga
    55921 tattgagaat ccctttaaag gttgaattat ccgtcacatt caaaacataa actccaaagt
    55981 acttgagttc gatatcctta ccagctgttt ttagtccttg atacttggcc atattttgcg
    56041 atgtttgcat gtagaattga ttgattcgca taaattcaac atcggaagaa ccacctgtag
    56101 tctcctgagc actacgaata tctgtaaaag gtgtcaacca agcataaatc atatgagcta
    56161 aagtggcatg ttgaacacca accgtaacga attgataggc accagcttcc ttatcttctg
    56221 tgtcatttac tttaaggact tggcgaatat cttccgaacc acctggaacc tctatataat
    56281 aaggcaaggg cactacaaat gccaagaaag tcacaatcaa ggccgcaatg acgtataagg
    56341 gccatctaat cttttttttc atttcttatt tcctccaaaa tactctcggg aacatagcag
    56401 gcaatatcct gaccaaactt caaaagctct ctaacgcctg atgaactgat atagagatgt
    56461 tcaggtcgac tatgtaaata aatagtctct atatcagaag acagctgatg attgtagtaa
    56521 tcaaaactgg cttcatattg caaatccgac gcatttctca agcctcgcac tagacaagta
    56581 gcacccaatc tttttgcaac atcgaccacc aattcatcat gagaagacac gactttaaca
    56641 tttcccaaat gtttcacagc cttttctaac ccccgtttac gattttcaag agggagaaat
    56701 ccttgtttgt ggggattaaa aaaaataccc acataaagct tatcaaagag tctgctcgcc
    56761 cgttcaatca tatccagatg cccatttgtc atcggatcaa atgagcctgt gaataagcca
    56821 atcttatctg acatagactg tcaccttact aattccataa atcttttcct tccagatacc
    56881 cagacaggca atctcttctg gaagttcaac ggccttatcc gtctcgcaca caaccataac
    56941 atcttcagaa aaaagctctc tctcagccat tttttcaata tctgctacga tttgttcctt
    57001 ggcataggga gggtctaaga aaacgaggtc aaattcccca gatacctgtt ccaatgccct
    57061 ctctgcatcc atcttgagga gttgaaattt tccaacttcc ttggtcatct ggatattttc
    57121 agccacgatg gtctgagcct tacggtctcg ctccaccaaa acagcactgg acatgccacg
    57181 cgatactgct tcgatagata aaccaccact acctgcataa aggtccaaga ctcgtccccc
    57241 ttcaaagtag ggaccaatca tgttaaaaat ggctccccta accttatccg aagtaggtct
    57301 tgtcgtcttg ccttctagtg tcttgagggg acgtccccca tagattcctg atacgatttt
    57361 catactgttt attataccaa attatagaca aaaagagaaa gaaaaccgaa ccttgcggtt
    57421 cgattctcta caaaatattt tcgtaagtat cgcggacttc ttgaggccaa acacttgttt
    57481 gcacttctcc gatgtgtctc ttgcgaagta ggaacatggc catacgagat tgtccaattc
    57541 ctccaccgat tgtcaatggg aatagaccat tcaacaaaga cttgtgccat tccaattcca
    57601 agcggtcttc atcacctgta atttccacct gacgtctaag agtttcttca tctacacgaa
    57661 ttcccataga agacaactca aaggctccac ctaaagactc attccagaca agaatatcac
    57721 catttagacc cttgtagcca ttctcagact cgcttgtcca gtcatcatag tctggtgcac
    57781 gtccatcgtg cggtttacca tctggcaact cgccaccgat accaatcaaa aagacggctc
    57841 caaattcttt acaaatcgca ttttcacgtt ctttcggtgt caagtctggg tagcgttcta
    57901 ccaattcttc tgtatggata aaggtgattt gttttggcaa gatagactcg atgtcatagc
    57961 gggcttcaac agctagctca gtcagacgaa tagccttata aatcttctca actgtttctt
    58021 ttagataaac gatgttacgc ttaccatttg ggataacctt ctcccagtcc cactggtcaa
    58081 cataaacaga gtgggttgca tccaaggaat cctcatctgg acgaagggct ttcatgtgga
    58141 caaagagacc ctctccttca ccaaagccaa aacgagccaa ggtgtggcgt ttccatttag
    58201 caagtgagtg caccacttca taagtagcat cagggatttg gagaaccttg accgatactg
    58261 gattttccac accagacagg ttgtcctgca ttccgtcacc gaccttactc aagataggac
    58321 cttgaacttc gacaacttct agcttatctt tcaaatactg ggtaaaagtg tttttgacaa
    58381 aggaaatttc ttcttgttga tggataaaac ttttcttcat agacaactcc tcaaaaattt
    58441 aataaacgta ttatacacct atttccaaga aaagaaaaga gaaaatttaa aaaaaatcag
    58501 tgtcactcaa aacactgatt tcatagacct tttagtcatt gcgaccaaag atacgtagaa
    58561 tacttaggaa aagattgata aaatcaagat agatgctgag agccattgac accacccagc
    58621 ctgtcgctac acgaccttgt gattgttcat aggcgaggcg aatcttttgg ttatcccaag
    58681 caatcaaccc tgaaaaaacc aaaaccatgg ctacgctaat catataatca aagaagccac
    58741 tagccaagaa aatattgact accatagcaa tcagtaaacc aatgagagct gccatcattg
    58801 ctcgaccaat cccactcaag tctttcttgg taaaaatacc aactgccgcc atgacaaaga
    58861 agagaagggc gctcgataca aaggcagata aaactgtacc cggagtatag aaagccacca
    58921 caaaactaag ggtaaagccg tttaaaacgg agtaaagtaa aaatactgga agagcagctg
    58981 gactatttct tgaagccatg ctactggcaa cgaaaaccaa agccaactcc gcaaaagtag
    59041 caatggtcaa ccagagacgc ccctgcatca aaaagtaaac caactgagac tgaaagaccg
    59101 tcaacataag gcctgatacc aaagcagata gtccgattcc cagaccaaca aaggcataaa
    59161 ccttagcgta aaattgattg agacctgcac ggtcatgtat aatagtgtga ttcatccatt
    59221 tctccttttc tgtgaacatc tttccttgat tataacaaaa aaagttaaaa ttagcttaaa
    59281 tggaagatta aaataccggc tgcaaccgca acattcaaac tctcggcctg ccccttcatg
    59341 ctaatatgga ccaactggtc tgcactttca gccataaggg gactaattcc ttgaccctca
    59401 tttcccataa ctagtacaaa attttctata gaaggcagtt ctctgtaatc aacagaatct
    59461 ttagataggg ttgttgctag cactgggata gctacctttt tagtttcgtc aagaagcgct
    59521 tgactagtca tccggtaaat gggcagatgg aaatgactac cttgcatgga acgtagggtt
    59581 ttgagactgt agatgtctgc cgacttatct gaaacaatca ctcctgtaaa acctgctgca
    59641 tccgcagttc gaatgatagt tcctacatta ccaggatctt gcacatcttc caaaaacaag
    59701 aacttgccct gactcaaatc agcttgtcct acttcttctt tttgaaccac ggcaacaatt
    59761 ccctgtggag tctgagaatc cgccaaatct agcaaaatat cctctgacac ccagacagtt
    59821 tgcgaaaaag tagctaactg atctcgataa ttttctaggg caaagatttt ctcaatcgtc
    59881 actccagctt ggacagcttc ttcaaacaag tgccagcctt caatcaagta ggcagacttg
    59941 cggtattttt tttggcgtaa tttcttggca ttttttacca cagaattggc ttttgaggtt
    60001 ataatagtca tagaaatatt ataacacaat caaaggggtt tggtatgcaa aaggttagaa
    60061 tgattgccca aggtagggta cagggagtcg gctttcgttg gggtgtttac agcttggcac
    60121 ttgaaattgg tggcatcaca ggtcgagtat ggaataacga cgatggcaca gtggaaatct
    60181 tagcccaagc agactcatct gctatcatgg caaaatttat ccaagaaatc cgaaaaggac
    60241 cgacaccttt ttcaaaagta agctacttag atgtcaaact aagcaacttt cctccctact
    60301 ctgactttaa aatcgcaaat taggtctcca gaactattgt atattttgta aaaaaacagt
    60361 agaatagaaa ggtataattt ttaaagaagg aataaaaaca gtgaaatcta ttaaacgttt
    60421 tgcactctca gctatgggag cggctatgtt gcttgtcttg actggttgtg tcaatgtcga
    60481 taaaaccaca ggtcagccaa caggatttat ttggaatacc atcggagccc ctatggctga
    60541 agctatcaag tacttcgcta ctgataaagg tctaggcttt ggtgtcgcta tcatcatcgt
    60601 aaccattatc gtgcgcttga ttatcttgcc acttggtatc taccaatcat ggaaggcaac
    60661 gcttcactct gaaaagatga acgccctcaa gcacgtcctt gagccacacc aaacgcgtct
    60721 caaagaagcg actactcaag aagaaaaact cgaagcccaa caagctctct ttgctgctca
    60781 aaaagagcac ggtatcagca tgtttggcgg tgtaggatgt ttccctatcc tccttcaaat
    60841 gcctttcttc tctgctatct actttgctgc ccaacatact gaaggggttg ctcaagcaag
    60901 ctacctaggc attcctctag gttctccaag tatgattttg gttgcctgtg ctggtgtcct
    60961 ttactatctt caatcgctcc tttcacttca cggagtagaa gatgaaatgc aaagagaaca
    61021 aatcaagaaa atgatttaca tgagcccact catgatcgtc gtcttctccc tcttctcacc
    61081 agctagtgtc acactttact gggttgtcgg tggtttcatg atgattctcc aacagtttat
    61141 cgtcaactat atcgttcgtc caaaacttcg caaaaaagtc cgtgaagaac tagccaagaa
    61201 cccaccaaaa gcaagtgctt tctctaaacc aagtggacga aaagacgtta cccctgaaca
    61261 accaactgct atcacaagca agaaaaaaca caaaaatcgt aacgctggaa aacaacgttc
    61321 gagataagaa gaaaaaggct tagctgattt gctaagtctt tttgcaaatc aaaagcccga
    61381 tgtttccatc aggcttcttt tctatccatg tacacgtttc atataatctt gataactttc
    61441 ggtatccatg agttttttag cgttcttgac gcgatctgct gttggtggtt tgactccttc
    61501 gagggaatat ggaattccaa gttcacgcca cttgaactca cccatggtgt gataaggtag
    61561 aatttcaaac ttatcaacat ttttgagggt cttgacgaac ttaccaagtt caatcaagtc
    61621 atcatctctg tctgtcaatc ctggaactag cacgtggcga atccagacag gttttccaat
    61681 atctgataga tactgggcac aagccaagat atttttatta gtttggctag tgacaatctt
    61741 gtgctgttct tcgttgattt ccttgatatc caaaagaacc aagtcagtga cagccatgag
    61801 tttgtcaaac ttctcaaggt aacgtggttt attacggaaa ggaagagcac aggtatccaa
    61861 ggtacagtgg attccttgtt ccttagcctt ggtgaagaga gcaatcagga aatcaatctg
    61921 caagagagct tctcctccac tgactgtaat cccaccctta tttccccaga aaccacggta
    61981 gcgcaaggcc tctgtcaaga catcatctac cgtccgttca cgtgacttat tggactccat
    62041 agcccaagtg tctgggttgt ggcaatactg gcaacgcatg tgacagccct gcaaaaagac
    62101 aataaagcga ataccaggcc catctactga cccaaagctt tctgtcgaat gcaccattcc
    62161 tgtcacttgt ccataatcaa ttgtttcttc agacatatcg ttaccttcct tgaaaacgtt
    62221 ttatagtttt attatatcac gacttgaagg aaaaacaaga tttttgccta ttttttagaa
    62281 agcaatctgt ttttcaattt cattttcaat ctattatcag attattcttc aaaatcgaag
    62341 ccatataagg ttgcaaaata gtcctcaggg cgctctgcac ggcggatttg acgggcttta
    62401 ccttcttcgg tatagaggat ttccgcagaa cgtaatttgg cattatactg gtagcccatt
    62461 gaaaatccgt gggcacctgt atcatgaatt accagcaaat caccgatttc tgtatgaggc
    62521 agttcgcgat tgactgcaaa tttatcattg ttttcacaga gtgaaccaac cacatctacc
    62581 gcttcagctg gtccatctgg atgggtcacg ttgctaatat gatggtaagc tccgtacata
    62641 gctggacgca tgaggttgac tgctgaggca tccacaccta gataggtacg gtaggtttcc
    62701 ttcttatgag tcactcttgt gactagagca ccgtgaggtg ccagcataaa acgacccaat
    62761 tcggtgaaaa tcttgacctg accaagacct gctgacgtaa gaacttcttc atacacctta
    62821 cgaactccct caccaatcaa ggcgatatcg ttcggctcct ggtctggacg ataattaaca
    62881 ccaataccgc cagaaagatt gataaagtct aacgaaatgc ccaacttttc cttgatttca
    62941 acagccagtt caaagagctg acgagccaac tctggataat agagatgggt cacggtattg
    63001 gacgctagga aggagtgaag cccaaaagtc ttggctcctt tttccttcaa gatagcaaag
    63061 gcttcaaaga gctggtcctt ggtcatgcca aacttagcct cctcaggatt gtccataatg
    63121 tctgtcccca gttcaaaaac gcctccagga ttataacgac aagagatgat ttctggaatg
    63181 cctgctactc tctccagatg ttcaatatct tcaaaggcat ccaagttaat ggtcgcaccc
    63241 aattcacgtg cataggcgta ttccttgtct ggcgtgttgt tggaagagaa cataatctca
    63301 gaacccagaa agtccagttt atggctcatc aaaagctcta cataactaga gcagtccaca
    63361 ccacaacctt cttcttggag aattttcaaa atagctggag ttggagtagc cttaactgca
    63421 aaatattcct taaagccctt gttccacgaa aaagcttggt tgacagctct tgccttctca
    63481 cgaatcccct tctcatcata caagtgaaag ggagtcggga actcggcaac aatcgcttct
    63541 aactcttctc tattgataaa tggtgttttc ataagcttcc ttctattctg tttgcaaaga
    63601 aaggctggga caatcgttcc aacctttagt tctatctctt atttatcttc gtcaaagata
    63661 ttgccaacct caacatcgat ggcttggttc ttgacatcaa tattagttac cttcaagagt
    63721 gacttgtagt caaactgctt ttcacgttct tcttgggcat tgtccgcaaa gaccgctaca
    63781 cctgccagtt ctgagtcgaa ctcgcgcaag agactaatca taccgttgac cgttccgcca
    63841 cctttcaaga agtcatccac aatcaagaca cggctgcctg ccttaagact acgttttgaa
    63901 aggaacattt tctcgatacg gtcaccactt gaacctgaaa catagttgac gctaacagtt
    63961 gaaccttcgg taattttcag gtcacggcgc acaatgacaa aagagacatt gaggacattg
    64021 gcaactgcat ttgcaagtgg cacaccctta gttgctacgg tcataaccgc gtcaattttt
    64081 tggtccataa agcttttggc aataatacga ccaatatttt tcaagatggc tggtgtgcta
    64141 agcaaatcag acagatagat ataaccacct ggcaagatac ggtcactttc tgacaacttg
    64201 gtacgcaagt cttcaaccat ttccttagca tcctgactcg agatagacgg tgtgaagatg
    64261 acacctccgc cagccccagt cactgtctgg atatgaccga tttcaatttc ctcaaaggcg
    64321 cgtttgataa tgacgatatc ttctgagatg gatgatttag cagactcata cttttcagca
    64381 aaagtattga gactagttag tttataagga ttattaatca aatagttgga aatgacaacc
    64441 atccgatcac ttcttcttaa tttcatttct atttcctatt ccatttttat tcaaaaaatc
    64501 aaaaagcaaa ctagaaagct ggtcgctggt ggttcaaaac actgctttga gattgtcgat
    64561 agaactgaca aaccctgtaa tatacctgca tatatacata cgacaaggcg atactaccct
    64621 agtttgaaga gattttcgaa gagtattcat ttttgtcttt tacttattat accatattca
    64681 cataaaaaaa cgaacattct tatcctaaaa aatgctcatt tttcttaaat tattaatcta
    64741 aatctggttt atagaaggaa cgattatcca tagcgaagat tttattggac atctctcctt
    64801 tatccaccaa agccagagct gttgacatca tcatcatgct tgcatccaga ttgtcaatca
    64861 tatggataat ctctgcctcc ataatacgtg gacggactgg acttccatat tcaagcaagc
    64921 cgtggtgact gaggatgaca tgacgaagca aaacgacttc ttccttggta tcatcgatgc
    64981 cgagttccat aactgtcttg gtaatttcgc tatcaatgag agcgatatgt ccaagaagat
    65041 tgcctctgac cgtgtactcg gtctggtctg gtcccgtcaa ctcgatgacc ttagccaagt
    65101 cgtgcaacat aatccccgca tagagcagac tcttattgag ctgaggataa acttcgctaa
    65161 tagcgtctgc caaacgtacc atggtcgccg tatgataagc caaccccgtt tcaaaggcat
    65221 ggtggttggt cttggcagct ggataggagt agaattcctt atcatacttg gtgtagagat
    65281 ttcggacaat ccgttgccag acaggatttt caattttgaa aatcatttgc gacatgtagt
    65341 cacgaatttc cttgacatca actggtgact tgaccttgaa atcggctggg tcattgggtt
    65401 caccagcttg aggcaggcgg agagtaattt gattgacttg aggggtattg ttataaactt
    65461 ctcggcgtcc tttcatgtgg acaaccttac ctgcggtaaa ggcctcaatg ttatgaggtt
    65521 gggcatccca gagcttccca tcaatctcgc cactatcatc ttggaaggta aaggctaggt
    65581 agtttttccc agctcgagtt tgcctcaggt cagctgattt gattaggtaa aagccttcaa
    65641 atagctcatc ttttttcatg tgactaatct tcatattctt cctcattttc ttgaaaatgg
    65701 agtagatcaa gcgcaggctc gccttctgac aactcaatgt gacggagcgt ccgctcgata
    65761 gctatggtac gacggtttaa tagttcatca atattgccag aggcatgttg gagatgtttt
    65821 tgtgccttaa ccagaatgcc accaaacttg ccaaactcgg tcttgacact ggcaagagtc
    65881 ttgctgatat ggtcggcact cttttggata ttaagggtct tgaaaccaac tgatagggag
    65941 ttaagaaggg ctgatagggt acttggtcct gcaacgataa tctgttcttc ccgtctcaaa
    66001 ttatcaaaga agaccggatt gcggacgatt tctgagtaga gaccttctgt cggaacaaac
    66061 aaaactccaa aattggtcgt ccgaggtggt gctatgtact tgttcctaat atccctagca
    66121 aagcgcttga cgcttgctag gagtgactta cgacagcgtt caatctcatc cttgtcacct
    66181 gtctcatagg cttcttccaa gcggtaataa tctgccagtg gaaacttaga gtcaattggc
    66241 agatagacgt attcttggtc gccttgtccg ggtaacttga tggcatactc cactcgttca
    66301 ctagagtttt caaccgttgc gtattctcgt tcgtactggg caggtgtcat gatgtcttca
    66361 ataatttgcc ccagttgcaa ttctcccaga atccctcgcg tcttggttcc agagagaacc
    66421 ttgttaagag ctccgacatc acgggcaact gtctgcattt ctccaaggcc acgattgaca
    66481 gactccagtt gtttagaaac tgtctcaaag gaagcctgta agcgtgtctg caaggtcttt
    66541 tctagttttt cctcgaccgt ctggcgcatt tgttccaaac gttgctcatt tgattcctgc
    66601 aaggcttgga gacgttggtc tgtcttgtct ctagtttgga ggagattatc tgtcatttct
    66661 tgacggactt gggtcagacc ttggtgcaat tcaatccgca cttcttgcaa acggtcgctg
    66721 acaaccactt ccaaatcttt ttggtctaac tggctggctt gtctggcttg gtcaaagcgg
    66781 taatccaact ggtctgacaa atgatctgcc tgatcctcca agctcttact taagtgtttc
    66841 tcctgcctat cctgcctttg ccaaatcaga aagagaccag ctaggttggc aattaataat
    66901 agaataagta aactttccat cctacctcct gtccttgcta tgcagtacga ccacataacc
    66961 atctgggcaa gtcaccgaca cttccctatc tatatattcg ttagaagcgt acactttttt
    67021 aaagaaaaaa ttctcctctg tcaactcata cttagctcca agaatagtca gctggctatc
    67081 ccgaactggc ataaaggcta gatagtcgta gtctgaacga ggttctagct gactggtccc
    67141 ttctgaacaa taggcaatca aattttgccc atcctcaatt tctatttgac gcatataggg
    67201 tgccaactta ggattgctag gtagaaagac attggccaac atatggtcaa tacggccacc
    67261 caaggcaccg aaaatagtga cctgagcctg aggattttgt tcaaagatgg ttaagagagc
    67321 caattccaga tctgtatcat ccttttctgg tcgggcttgg acaaaatact gggcacgttt
    67381 ttgaatcacc tgtcgctctt ctgcagtcac agaatcaaaa tctccgactg ctagagcaag
    67441 aggtaagtct tcttccaaga cccagagcga gcctcgatcc accccaacaa aagcatcaaa
    67501 atctgtccga taatgaccgc ggtttccgcc tgcaaaaact gcaaccctag tccagttgtt
    67561 ttctgagagt ttgtactcgc tcattgactt ctcccttaaa gacataggaa cctgctacaa
    67621 aaacagtcgc accagcttct ttggcttgag caatagtttg gtcatcaatc ccaccatcca
    67681 cttcgatttc aaagtttaaa cctttttcct gacgaagagc aaccaactca cgaaccttat
    67741 ccatggtttc tggcagaaag gcttgcccac caaaacctgg attaaccgtc atgactaaaa
    67801 cttggtcaac tagatgaagg acgtgcttga tggcttcaac tggtgtgcca ggattgataa
    67861 cgactgaagg cttaactccg agtgaacgaa ttttttggag ggcgccatga atatgaggcg
    67921 ttgcttctac atggatactg atgatgtctg cacctgcacg cgcaaaatct tccagatgat
    67981 gctcagggtt tgacaccatc aagtggcaat cgaaaaccat cttactatga ggacgaaggc
    68041 tctcgaccac acctgcacca aaactgattt gcggtacaaa atgactgtcc atgatatcga
    68101 tatgggcata ttctgcccca gttgcttcta gacgtttgat ttcacgttca aagttggcat
    68161 aatctgctgc cagaattgac ggagcaatct tgtattgaga cataggtttc tccttatttt
    68221 ggaatttttt tgctgacttt tttataggtt tctctacgat tttcaatttc gctgaggaat
    68281 tgcaggtagt tgtcaaaacg gaaggtggca atggtcccct cttctacagc tggcttgacg
    68341 gcacaagacg gctcatgggt atgggtacaa gtacgaaact tacaatctcg gctgacagta
    68401 gcaatctctg gaaaggcctg attgaggtct tcagcccttg atacttcata gtccagagat
    68461 gaaaagcctg gtgtgtctgc gattttaccc ccattgagat tgtaaaaact aacagctcga
    68521 gtagtatggc gcccacgacc cagactgtct gagatttctc ctgtttcaag attgagatct
    68581 ggtgcgattt tgttgagaag agttgacttc ccaacacctg tctgccccat aaaaaccgta
    68641 accttgcctg ttaacaaagg caggagttcc tctttactgg tcacaaagtc atagccgatg
    68701 tcaccatagg tctgctggta aaaatccagt tctcccctat cttccaacaa atccattttg
    68761 gaaatataga caatgggatg gatgcccttg tgctccaaaa gaaccaagaa acgatccagc
    68821 aaattgctgt taaaatcagg ttccttgacg gacatgatta ctacagcttg atcgatattg
    68881 acaataggcg gacgaaccag actgtttttc cgttcgtgaa ttttgaggat atagccttct
    68941 gaattttcct cggcagagaa atctacccag tccccaacat aaggggtatg gcctttttta
    69001 cggaaattcc cacgcgcgcg tgtttgataa acctggccat cactctccac atagtagaaa
    69061 cctgccaagg ctttaatgat ttgtccctgc atcttagagt ccttgccctt taagtgcgtc
    69121 tgctagaccg gcaaattctg ccaagctgag agcttcccca cgcacacttg gtgacaagcc
    69181 tgcctggtcc aaagccttgg tcagcttgtc cttgacctct tcagtcttac caaagtaacc
    69241 tgtcaagtta ttccacaagg tcttgcggcg atgggtaaaa ctagccttgg aaaccttaaa
    69301 gaaaaagttc tcatcttcta ctgctacggc tggctctgga cgacgcacca ttttcaagat
    69361 ggctgaatcc acatttggcg ctggcacaaa gaccgtacga ggcacgataa aggcaacctt
    69421 ggctgtcatg taatactgca cggcgataga caagctaccg taagccttgg tgttaggctg
    69481 ggctgaaatg cggtccgcta cttctttctg catcatgacc acaaactcac aaaaaggaat
    69541 gccactctca atcaagtgca tgagaatagg cgtcgtgatg tagtaaggca aattagccac
    69601 taccttgatt ggcaggtcag gatttttaaa attctggata tgttgcgcca aatcaacctt
    69661 gagaatatct tcgttaacta cggtcacatt atcaaaatca cgcagagtat ctgccaaaat
    69721 tggcaccaaa cggtggtcaa tctcaaaagc catgacttgg gctgcacgct cagccaaaaa
    69781 ttctgtcaag gcaccaatac ctggcccgat ttcgatgaca ttgacctgat catcaatttc
    69841 agccgtatcc acaatttttt gaaggatatt ggtatccgtc aagaaatttt gcccaaagga
    69901 ctttttaaag gtaaaaccgt gacgctccaa cactgccttg gtcacgctat aatctgcaat
    69961 tctcatctat tctcttttct attatctgtt actactattg taacacattc cccttgtatt
    70021 ttgggaatga aaatcatacc aaaaaactat ctttcctcat gaagaaagat agtcttggaa
    70081 atctttaaag agggacttag cgcttctctc gaaacatacg ttcatactct tcgaaaatct
    70141 cttcaaatca cgtcagcttc accttgccgt actcaagtac agcctgcggc tagcttccta
    70201 gtttgctctt tgattttcat tgagtatcaa aaaaatcagc ttcttgataa cttcgatttt
    70261 cgggtagggt caaatccaca tcctcctcca catcatccac tgtcagttca accgtttgag
    70321 gtaaattttt caaacgataa tgcttttgcc tttacccttc aatactagca aaatcaagca
    70381 aatagccatg cactcggatt tgaaccaaaa ggagatgatt ggtcatattt tccatgatga
    70441 ggatatcttc taaaccacct ctggcactag gataatcaga taccctgcga atacggattt
    70501 tttcacacat gagcaagttt cctcatatca atgatttcat cagccttatt ccagactagg
    70561 ggattatggg tcgcaatgat gataattcga ttttcatctt tcaaatccac caagagattc
    70621 ataacctcct ctgaattttc aggatcaaga gctgctgttg gttcatctgc caaaatcaag
    70681 ggtggatttt tcaaaatagt cttagcaagg gcaactcgtt gggcctctcc cccagataaa
    70741 gtatagattt tttgttctaa atccaaatac cctagattaa ctttttctaa agcccccact
    70801 tgcctttcca aacgttctac ttttgagatt ttctgaccaa caaaacccaa atccaaattt
    70861 tctttgattg attggttttc taagaggcca aaattttgaa agagatagcc catctgatct
    70921 cgaaaatact cacgagtggg aatggttttt aaatctttcc cctgatagag aacccttcct
    70981 ccatctatct tttccagctt tcccaagata ttcagcagcg tcgtctttcc gcttccactc
    71041 tttccgatta aggcataaac cttgcccttc tccagcttga gattcaaacc agagaaaatc
    71101 gcgcggtcat taaatttctt ttccaatcct tgaatatcaa tcatcttatt ttcctttcaa
    71161 tactgccatg ctaccagctt cttctttttt gtcctgcctt actaaaatca agagggcgtt
    71221 aagcgtaaac aaagctacaa ctagagcgct aatcaaacca tctcttgtca aaatactaga
    71281 taggactagg ccaagcaaga gaactcctcc ttgcgccagt aaatacttgc catgaagctc
    71341 atagattgtc ataccagcaa gacgtttaat cataagctcc cgtctgaact gctcaaaata
    71401 gagaagattc atggaatcaa ataacaagat agccgtagac agggtcaaaa tcgtcccaat
    71461 aaggagagag taaaactcca cccgtttgtc atttagtacc ttggcaaaaa atagctggct
    71521 ttttaccaag taagaaacct tgtgatacag accttgctct tttagagctg tgatgctgtc
    71581 tccatatcga tctagtttca aggcactatt agccgtagtt ccccacaaca tccctgcaac
    71641 aggtcttgtt ccagtcgctt gcggcgttag aactacaata atcggatctt ttaggtactg
    71701 gcgtgttgtc ttgtacccat cattatagag gaaacgttcc tgtcctgttt ctgtaaaagc
    71761 tagccttacc tgtgggaggt agtgtttctg actcgtcact tctacacttt cagatgaaaa
    71821 gttttgcagg taatctgtaa acaatccttg gtagtaggca gactgctctc gcaagctctc
    71881 aggcaagatc agcccaaact ctccctcaga caagttttgc atcttgtcca taaactctga
    71941 agaaacggta atcttttcct ctatcagata gcgcggtgag acatagataa cattccctga
    72001 cggtgtgtag tcactgagac gattgccatc taggtccact tctactccat ctgagaaatt
    72061 gtcaacattg ctcataatat aaaaagagtc tgtattggct aaccgttctt cagtaaatgt
    72121 ctgccactca cgattatcct tacgcattcc ttcttcatcg gcaaatgcac tagaccaacc
    72181 aaaggagaga cggtaacggt ctgaggactg gctccattta tcgcttgcct tctccatctc
    72241 ctgcatttca cggtagttgg ggaggagagc tgtcgcactc aagccgacca ccaatacagc
    72301 taagagttgc cccaccatca ttaatgtcat catacgtttg agagggagtt tccctttcaa
    72361 tagatccacc agactatttt cctgtaaacc aagtagatag acgacactta gtaaggtaga
    72421 aatccctgcc agggtcaatc cataaagtag aagagcaatg atgaccagtt gcaccgttgc
    72481 cataaacaag gcaccttgat accagagaat ccccaatccc aaaagactgg ataccagcac
    72541 tgagcagata aactgtctca catcttctaa cactggtctg agagcaactc caaacaagct
    72601 ctcaccagct attaagcgaa tccctgcctg acgaagggat ttgatccgat aaatcagggt
    72661 cagactcata aaggtcagca gaaaaatagc taaactcagt agcaccatag gggtggccgc
    72721 caatagtaag actatcgaaa atggatcttc tccattcgaa acaaagcctt gatagccaag
    72781 ttctttcaag gtggtctgta agctcactcc atccaaactt cctgacacaa tcaagtaaga
    72841 ccctaataaa tcactcgttt ctgcactctc cttggaggaa atggtcagac cttctggaag
    72901 ctctccctca ccataagtgg cataggtaaa gagtgtttct ccagcttcat ttggctcaac
    72961 gattcgacgg gcgatgagac tattatgctc taccgccaag tgactcaaaa cctctgtcac
    73021 ctcttcgcga ctagctactg gttgatttat catcattcct gtcacatcaa cagaaggata
    73081 gttaccaaat aaaatctctt ctcgatggtc aacggaagtt atcaccatat aaagcgatac
    73141 caataccatt gaaatcaaaa taaataaacg tttcatcatt tcctccaaaa agttacttgg
    73201 tcacttagtg agaaggtgac cacagtcact gcgatgttaa gaagcttatt aagttctttc
    73261 tgctagcaac atcttcaaat acattatatc cgttttttca agaactatca aggacatcaa
    73321 tgtccttaaa atctaaccat ttcgtgtcat ttttagctta tatctaaaaa acagccctaa
    73381 agacgaactt tagaactgtt ttgatgcgag aacaaggaca tttttgtcac tgattcacta
    73441 tgtttataaa tattttttga catcctcttg ccattcctct gtcaatttct ttactagaaa
    73501 ttcatctcca attagctgcg caaatgtttt agaagactga taaaatgatt cagctaaact
    73561 aaaatctctt tcttctctta atgcttgctt ccacaaaaac ataaatacaa gaggtttctt
    73621 ttgataatct tgagttttat ccataatttc ttgtaaacac gatagataat cattaaaaca
    73681 atcagttact cctacctttt caagacaaca cattcctgaa ataagagtat ctctaattat
    73741 aaagaagttt tctaatttag ttaccttttt ctgttccaaa agaaagagca ttagctcttc
    73801 gatttgattt ataaatttgg caagatcttt tctaatgagc atttgataaa aaaacaaacg
    73861 aatcaacaac atatcatttg ttgaataaac ttctttttct atgatctgag gcatatgttc
    73921 ctcaagtatt aactctgcat attcaggcct tctagttcta gaagtatcca aacacgcctg
    73981 caatacttca catgctaatt gttcttcttt aggaagatta tcaaagtatg ttttataaat
    74041 ctcttccaaa cacgcttcct tcttatcgta ctcctcttct ttaccataga ttggttcacg
    74101 taaaatctga tatttcaatt ctaaataagc aggaggaaga gctgaaaaat ccggcataag
    74161 gctataaact ggaactccta gccggcgagc aatatagtct aacttgggca aactcggttg
    74221 cgaagctcca ctttcaattc gcgacagttg acgaactgtc agttcttgct catctccaca
    74281 aaaatctgga cgactaattc ctttttctat ccgaatctct ttaatttttt gaccaattaa
    74341 catcagacgc ctcctcttct acctgcttcg aaaaatactg tgaaacttaa aaaattgtaa
    74401 cggctacatc tttcctactc ataagatttc atagcttctt ccacttctgc caaagtaacc
    74461 ccaaacaact ctaggcgttt gaggagttgc ttgccgttag aatagccgat tcggagagtc
    74521 tctccgagat attctctacg cttacggctg tctgcccctg ctagaaaacc aaggcgaatc
    74581 aagtcgctac gactaatgtc aaactgactc tcatgttcaa attgttctgt cacctgagct
    74641 agagccgttt tcaggtcttc atagctggca tgctcaattc ccagagaacg ccccttggtc
    74701 ttggacttgg gaacagcttc atctcgcttg agaaaggcat gctgaactgt tggaatgacc
    74761 gtcatgatca tgcgccgaat ccgttcccca ttaaaatctg ggtctgtaaa gacaatgact
    74821 ccatgacgtt ggtgcaggcg ctgaatccgc tctatatcct gatcattgat ggcagaacct
    74881 cgagtctcat aggtctccac atcgaaataa cgtttgagat tgaccgtatc atcgcgacct
    74941 tcaaccacga taacttgaga aattttctct ttcattactt gctgtccaat ccaaaaattc
    75001 gttctgcatt tgcagtcgtt gctaccgcca gctcttctgt cgtcatacca cgcaagtcag
    75061 cgataaagtc gaccacatag cgagtatagg ctgttttatt ttcacgacca cgcttgggta
    75121 caggtgctaa gtaaggcgca tctgtttcca ccaacatctt gtccaaaggt aactctttag
    75181 ctgcttcttg gaggtcagtt gccttcttga aagtcaccac tcctgagaag gaaatggtca
    75241 taccaagatc cacaaacttc tctgcccact caagcgtccc tgaaaatgaa tgcatgatac
    75301 caccacgagg accaacgccc tcactcttga taatctcata ggtatcttcc agcgcatcac
    75361 gggtatggac aacaaaaggc aaatccaagt ccttagatag ctgaatctga cggcgaaaaa
    75421 cctgctcctg cacctctttg ggcgctgtca tccaatggta gtctaagcca atttcaccta
    75481 aagccacaac cttggaatgt tttaacttat ccaacaagta agcctcaact tcctctgtat
    75541 aagtaccagc ttctgtagga tgccaaccaa tagtcgcata gagctgctca tactcatcta
    75601 ccaactccaa ggcatgctca atcgtcggtt tatcaaaacc aacaatattc atctgtgtca
    75661 cacccatctc agcagccaag gcaatttctt ctgtctcacg acctgcaaat tcttctacat
    75721 tcaagtgtgt atgtgtatca aaaatcatct cttctaacct cgttttctat cttctattat
    75781 accaaaaaag aggaggggca cctaattttt cggtttcccc tcctctcttc aatagagagc
    75841 tattctgcta tcttttctat ccgatattgc ccatctccta ttccacagtt agagacagaa
    75901 gagattggct acattgatag aatattccta ttcagctaaa gtatgtgatt atcttgggtt
    75961 ctcacttttc tcacccatca ctaggattga tgacttctca aaatccccct tataatctaa
    76021 ctttaagtag agaatagaat tttctagctg ttctattttc tacgtctagt ctttcttcct
    76081 agcaaagcaa aaccacttgt tgccaccact agaccaagac tagcaagtgc tgcacttgat
    76141 gctgaacctg tgttaggtaa ttgtttgcca gcaggtgact ggtaggtaac atcttgcatt
    76201 gttcctgcag ttgcttgcgg tgcacttgtt gtcttaggag cagcattagg agccactggt
    76261 ctcttaggaa ctgtaaccat ggcaatggct tgcactccaa tcgtttctgc ttccttcaca
    76321 tcttccatag ttttcgcatt ttcaatctct ttgagagctg cttgtttttc tgcttccact
    76381 cttgctaaaa gttctgcttt ttctttatca gaaagcggtg cgcctttgat ttcatcctgc
    76441 ttgttcttgg ctgctttttc aatggcattt ttagctgatt ctttttcagt agctaattgc
    76501 ttagaagctt gtgattgagc tgagttttgt gaacctgtgt gagctgatcc acccgcctgg
    76561 ctaccaccgc cttcattcgc attagcatct gagcttccag tattgcctcc cttatctcca
    76621 cctggtgtag tttctagctt atactctggt gtagcttctt gagttacaga ttcacctttc
    76681 gcagattgtt gaactgtatc ttttcctaga atcgtcacta ctgaaccatc tgggaatgtg
    76741 attgttgctg taccatctcc agctacattg attgtcgctc cgtctaatgc tgaaccattt
    76801 gcttgtaaaa tagcaacctt aactttttct tcatctgtta aatgagttat atcttttaca
    76861 tctactcttt gagcaggtgc tttaacagtt gatttttcag cagtcggttt agtgctatct
    76921 tgtgcttttg gatcttgtgc taccaattga tttcctggaa ttgtaatagc tgaaccatct
    76981 ttaaagacga ttgtcgctgt gccatctcca gctacttcaa ttttatagta aaataaaata
    77041 ataacaggac aaatcaatca ggacaatcaa atcgatttct aacaatgttt tagaaacaga
    77101 ggtgtactat tctagtttca atctactgta acatcgcttc cgaatccatt tgcatctact
    77161 gaactttttt acaaaaataa aaatcagtag actcgagttc ctactgattt ttgatagaat
    77221 tcgtttggat tatgcagcca aaactttgcg tcctttacga cgacgagctg ccaatacgcg
    77281 acgaccattt ttagttgaca tacggttacg gaatccgtgt ttgcgcgcac gacgaagttt
    77341 acttggttga taagtacgtt tcacgatgaa tacctcctca tagattttgt attcgtttag
    77401 ccggctataa agtgatcagt tactaaacat actttactat tctatctgat tctttcactt
    77461 ttgtcaatag ctctaggcaa atgtttccag ctttttcgaa tgcaagccct atctacgata
    77521 ctgtttcaag aaacgagtca tcttttcttg gatttgggct aactcatcaa cacgaggaag
    77581 gtaaacgata cggaagtggt ctggttcctg ccagttaaag cctcgaccat gaaccaagag
    77641 aaccttttcc tgcttcaaga aatcaaggac aaactgctca tcatcatcga tacggtacat
    77701 attgcggtcg atttttggga agatatagag ccccgccttg ggtttaacgg cagacaaacc
    77761 tggaatatct tgaatggcat tatagatgaa atttctttgc tcgtagattc gtccaccagg
    77821 aagaagcaat tcatcgactg attggtgacc ccccaaggaa gtttgtacga cttgttgggc
    77881 caaaacgtta gagcaaaggc gcatattgga cagcatattg agcccttcga tatagccctt
    77941 aacatgagtc ttagggccag acaagaccat ccaacccaca cggaaacctg ctatgcggtg
    78001 ggattttgac agaccattca tgctgacaca gaagacatct gatgccaagc tcgccacagg
    78061 cgtatgcaca tgtccgtcca ttaccatgcg gtcatagatt tcatccgcaa agataatcaa
    78121 atcgttttga cgggcaatct caataatctc cagcaagagt tccttaggat aaagggctcc
    78181 agttgggtta tttggattga taaggacaat tgccttggta ttggaagtga tttttgactt
    78241 gatatcgtca atatctgggt accattccac agcttcatca cagatatagt gaacggcatt
    78301 tcctccagct aggctgacag ccgccgtcca tagaggatag tctggcattg gcactaagac
    78361 ctcatcccca ttgtccaaaa gcccctgcat ggacatgaca atcaactcac tgacaccatt
    78421 tccaaggtaa atatcatcaa tatctacgtt tgggaatttc ttcagctggc aatactgcat
    78481 gatggcctta cgggctgaga aaatcccttt ggagttagaa tagccttcac tatcacgcgc
    78541 attcataatc aagtcatgaa tgacctcgtc tggcgctgta aagccaaatt ctgctggatt
    78601 tcctgtattc agacgtaaaa tcttttctcc attcgctcgc atccgcatgg cttcttccaa
    78661 tacaggacca cggatatcat aagcaacatg ctctaactta ctagacttgt tatattcttt
    78721 catcttgttt cctcaattca tcaggatagt aacattatac cactagaaag agaatgcgac
    78781 aagtttactg aaatgtgtta ctagtttcgt atagaagaaa aaccttgcta aaggcgaggt
    78841 taagaacgta gagatagcag gtattttgca aagacacatc acataccaaa agataaacct
    78901 agaaaaagca agcctagaaa ggagtcataa agaagattaa acatgaggaa aagccccata
    78961 tcatcaagta atcccaacgc ccacttcgtt ttgcaactag aaataagatt agatggtaga
    79021 gtacatgaaa gactaaaaat ccaataaaac ctggataaag aagcggtacc agactctcta
    79081 attgacagat catgatcact tctaccaaga ctgaaactag gataattcca taatacagga
    79141 aatttgattt ttgaaaagag tttttcatca ttctcccttc cttcacttct ttcctgctat
    79201 cctttctttt attttatcat atatttatat agagtttaag ccctaatatt cttttgaaaa
    79261 atactttttt tgctttactt ctatagtgaa aaggtttaca attatagtaa gaaaatttca
    79321 ggaggtttca ttatggcaca acgttaccaa aatatcatgg tcgcaatcga tggttctaag
    79381 gaagcggact tggcttttgt caagggagtt cattctgctc tacgaaacga cgctaaactc
    79441 accatcgcac atgtcattga cacacgcgct ctccaaagcg tatccacctt tgatgctgaa
    79501 gtttacgaag aactccaagt cgacgctgaa agtctgatga aagagtacga aaaacgtgct
    79561 aaagatgctg gggtagcaga tgttcatatc gtcattgaaa tgggaaatcc aaagaccctg
    79621 ctagcacgta ctattccaga tgccgaggaa gtggacctca tcctcgttgg cgcaactggt
    79681 ctcaacgcct ttgaacgcct cttggtcggc tcttcatctg aatatatact ccgccatgct
    79741 aaggtcgatt tgctggttgt gagagaacaa gaaaaaacct tataatcaca aagaaaagga
    79801 gcccctagct cctttttgtt tacgatttat ttctctcttt atggcgttcg taagccttga
    79861 gctggcgctg cagttccttt ttaatagcag gttctggagc atatttttct tcccaattat
    79921 ctggttttaa gattttatgg gtcactggat caaaatgagc cttgccatct ggaaaaattt
    79981 tccccatatt ggcctgatgg acaatatcaa aaatacgttc tgggtccacc cccatcaaga
    80041 caaaactgcc gtaggtgaag taaagcgtgt caatcaaggc atccacttgc cctatcaaat
    80101 cttgctgagc aggtgtcttc ttggctactt tatctgctgc cttatcaagg gtctgatgaa
    80161 gttgcgatac agcttgacca aaatcttctt cagaaggact ggctgctcga acaaactcca
    80221 ccaattcttc tattttaaaa ccagccctat gggttgcacc ctctaaatcc caagctcgag
    80281 gttcttcttg ggttcgttca tccatcatgt ggtggaaggt cttgacctta ttgaaatgat
    80341 agtcacggct gacaaagact ttttctgaag acaaaacacc aaaatgttcc aaggccttgt
    80401 ggattccatc ttgttgattg ctagtggtaa tgtgcttggc agcttccttg acactgctac
    80461 taccatttcc catagcgacc gacataccga cgccagccag catttcaaga tcattatctg
    80521 agtcaccaaa agccatgact tggttgaggt caaagccata ttctttccca actcggcgaa
    80581 tgccttctaa tttagaattt ccctgattga tgacatccga tgcaaaagga ttgctacgtg
    80641 tcaatttcaa gtcttcaaaa tcagctgccg ccttctcaga ttcttctggt gtcatcagca
    80701 tcaaaacttg gtagataggc tgattcatca ggtgaagcag gtcctcttcc ttttggggaa
    80761 caaccttgct gaccatgcga ttaaaagact gactcaccgt ccgagttaaa acagagggaa
    80821 cgaagcgact aattcgttgg gaaaaagaac ccagaccaaa ggacatgatt ttagaaccca
    80881 acatggcatc cttggtccct agagcaatct ccgtgccctc ttttttagca tagctaatta
    80941 gatggcgcaa atgtaacttg gaaatagggc tcgtgaacaa gactctgtct ttactaaaga
    81001 tatactggcc attataggtt accgcaaaat ccagatccaa atcgtccatc aattccttaa
    81061 caaaaaaagg tcctcgccct gtcgctacgc caactagtac cccttgttct ttgacaatct
    81121 taatcgcgtc cttagtggat ttcaaaacac tcttgcgatt gttgaccaag gttccatcga
    81181 tatcaaaaaa aacagctttg acttccatcc tattccaatc tccccttttg tgatacaatg
    81241 attataccac atttcagaaa gagtgagtaa atcatgccta agaaaatcct tgttttacat
    81301 acgggtggaa ctatttccat gcaggccgat gcttctggcg ctgttgtgac gagttcagat
    81361 aatcccatga accatgtgtc caacccactt gaaggaatcc aagtccacgc cttggacttt
    81421 tttaaccttc caagtcccca tatcaaaccc aaacatatgc tggtcctcta ccagaaaatt
    81481 aaagaggaag cagataacta cgatggagtg gtgatcacac acggaaccga tactttagag
    81541 gaaacagcct atttccttga taccatggaa gttccccata tgcctatcgt tctaacagga
    81601 gccatgcgta gctccaatga gctcggtagt gatggtgttt ataattacct aagtgcttta
    81661 cgagtggcca gcgatgacag ggctgctgac aaaggagttt tggtcgttat gaacgatgaa
    81721 atccacgctg ccaagtatgt caccaaaaca catacgacta atgtcaacac cttccagact
    81781 ccaacacatg gccccctcgg tctcatcatg aaacaggaaa tcctctactt caaaacagct
    81841 gaacctcgtg ttcgctttga ccttgatcac atacaaggtt tagtccctat catctcggct
    81901 tatgctggta tgacagatga gctgattgat atgctggatt tagaacactt ggacggtttg
    81961 attatccaag ccttcggagc tggtaatatt cccaaagaaa cggctcaaaa attagaaagc
    82021 cttctgcaaa aaggaatccc agtcgctctg gtatcacgat gctttaacgg tattgccgag
    82081 cctgtttatg cctaccaagg tgggggcgta cagttgcaaa aagcaggcgt tttctttgtt
    82141 aaagaactca acgcccaaaa agcccgcttg aaactcctca tcgccctcaa tgccggacta
    82201 acaggacagg ctttgaaaga ctatatggaa ggctaatact cttcgaaaat ctctgcaaac
    82261 cacgtcacgt cgccttaccg tatgtatggt tactgacttc gtcagttcta tctacaacct
    82321 caaaaacatg ttttgagctg acttcgtcag ttctatctac aacctcaaaa acatgttttg
    82381 agctgacttc gtcagttcta tctgcaacct caaagcagtg ctttgagctg acttcgtcag
    82441 ttctatctac aacctcaaaa cagtgtgttg cgcagccttt aaccagccgc ctagtccgct
    82501 ctatggtatt cattaagtca acatctcttg tttaagagca caaaatcagg aaatcttctc
    82561 gattccctga ttttttctat ttacgttttc gtgttgagct acgttctgtc aaaccatgag
    82621 gtaagagaac ttcacgttct tccaactctt ccttatgcat aatcttggtc aacatacgca
    82681 tactaatggc accaaggtca taaagaggtt gggcaatcgt tgtcaagttt ggacgggtaa
    82741 agcgtgagat ttgtgaatca tcactagtaa taatttcaaa atcttctggc acagaaacac
    82801 ccttatcagc caaaccgttc aagactcctg ctgccaactc atcacctgtc acaactgctg
    82861 cagttgcatt tgatgaaatc aaacgctctg ctaaggcgta accatcatca tagctatatt
    82921 tagattcaaa taccaaaccc tcactataag cgattcctgc ttttttcaag gtttccttgt
    82981 agccaactaa acgaacctta ccattgatgt catccactag cggaccgcta acgaaagcaa
    83041 tacgctcatt ttctttagca aggtaactca ctgcatcaat tgttgcttgc ttatagtcaa
    83101 tattgacact tggcaactgg tgctcaacat cgacagttcc tgcgagaaca atcggagtac
    83161 gtgaacgcga aaattctgag cgaattttat ctgtcaagtg ataacccata tagataatgc
    83221 catctacctg ctttgaaaag agggtattga caacagaaac ttctttctcg ttatcttcat
    83281 cgctattagc taggacaata ttgtacttgt acatttctgc aatatcatca atccccttag
    83341 ccaaactcga aaaataacca ttggtaatat ttggaatcac gacaccgaca gtggttgtct
    83401 ttttacttgc aagaccacgc gcaactgcat ttggacgata atccaagcga tcaattacct
    83461 ctagcacttt tttacgggta ttctctttta catttttatt gccattgacc acacggctga
    83521 ccgtcgccat ggaaacacct gcttcacgag cgacatcata aatggttact gtatcatctg
    83581 cattcattcc ttttcctgtc ctttctatct cacacattct tttacaagta gaggtactga
    83641 ttgaagctct atatctactt acaaaagtga agatgtgaaa atttcgtttt catatttcta
    83701 cttattccat tctatcacta attgtaaaca ctttcaagtg ttttttgaag attgattgaa
    83761 aaaatttcat agaaaaccta ggtttagctc cttgctacca ccttagacta aacaaaaagg
    83821 aggaaactaa gccctcctaa agttatagta aaatgaaata agaacaggat aaatcgatca
    83881 ggacagtcaa atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca
    83941 atctactata ggtattgttc cattcactac cgtcaatttt agcacatagt cttcatgaaa
    84001 atattatatc atcataacca accagattct tttgcgatat tagctgcctc tgttcgatta
    84061 ccagcatcca attttgaaag aatattggtg acatagtttc gaatagttcc gtttgagagg
    84121 taaagctgat ctgcgatttc ttggttggat aagccccggg cgatcccctt taagacagca
    84181 atctcttgtt ctgtcaacgg attgggacgg gtcatcacca cttccatcaa ttcaggcgaa
    84241 tactccttgc gtccttcgag gacggtgtgc aaggtttgca tgaggtctgc aacgcttcgt
    84301 tcctttaata cataagcatc cactccagcc ttgaccgcac gttcaaaata cccagcacgc
    84361 ttgaaggtcg tcaccacaac cacctttgtt tcaagccttt ctgatcgtat ccactccaag
    84421 acttcaagac ctgtcttaac aggcatttct acgtcaagga tggcgatatc tacagactcc
    84481 ttttctaata gttggattgc ttcttgccca ttcttggctt gaaggacaga ctccacatct
    84541 ggttgaagcg tgagtaattg acacatggca tctcgcaaca tactttgatc ttctgcgact
    84601 aatactttca tcttagtttc tctccttata aggtagtcga acttgcactt ccgttggatg
    84661 tttctgactg attacactta cttctcctga aaatggaaaa acacgatctc ggattgtatg
    84721 gagctcatct ccttttagaa aagcaaagcc gcagccatca tcacttactg ttaaaatgag
    84781 ttccttctct gtccgttcta attttaagta agctttagac gctttggcat gtttgatgat
    84841 attggtcacc aactcaagca aaatcataga agccattgac tccaattctt gagtaaggct
    84901 agcagtatct agttggttat ctgtttccac ctcaattcca gcaatttcta acatcttttt
    84961 cacagtctct agttcggatg tcaaagttct agacttaaga ttttccacaa tggttcgaac
    85021 ttcacgcatt gattctttgc taatttgctg tatttctctt aattcctttt ccacttgtgg
    85081 ataagcctgc atttgaaata gctgcaaggc tagatctatc ttgacactaa gcatagcaaa
    85141 ggtatgtccc agactatcat gcaaatcctg accgatacga ttgcgctcat tttctgctag
    85201 caatagattt atctgggtat tttgcttgac ctgagcttct ttcaaatcct cgacaaggcg
    85261 aattcgaacc gagcccaaag tcatcaaatc gacaaaagta agaattacaa gcatatagac
    85321 tagaaactca acttcgattc tctgaaaaat caaaagtcgc cccacaacaa ggacttgagc
    85381 aaggagaaat gtccatacat gtaaagactt taaactacgt acgccaaaat gataaattaa
    85441 gatattggaa aggaaaaaga aaaaccagat ataattccca gcaacaaagg cggtattccc
    85501 agctacatag accagcatga tcccccagaa aagccaagat aggcgctggt tcttagttat
    85561 taaaacaccc aaatacgtca ctacaaatag aatatcaacc aataaatgcc aagcaggaag
    85621 ctccccaatc actacaggta ggatgggaaa aagcataaaa atcaaactgg tccaaaacat
    85681 atagtgtatg cttttcagtc tttcaagcat taagcattct ccttatgacc ttgaaggtaa
    85741 atagtcaaac caaataaaac tgctgaaaaa acaagtaaat aaactgtggc tgatagattg
    85801 atgccaccct cgtttaagaa ggtcttgagc aactccatca attgataggt cgggagacac
    85861 ttaccaactg cttgcatcca gtctggaaat aaagaaatgg gcatccagag tccgcctaaa
    85921 acagccaatc ctagataaag aagattgccc acaacagaca tcagctgact agttggtaag
    85981 agagtcaagg tcaagccaag tgctacaaaa gcaatactcc ccacaatcag caaaatcgca
    86041 gctccaaccc attttactag aggcatgtct acacctctta caaaatgtcc aactgtaaaa
    86101 acaaccagaa ttgagaccaa ataatcaacc agcatacttg ttatctttga tagataatat
    86161 tctaccatat ttacagggct atgacgcaat gttttctgcc agttgttcat cttatcggta
    86221 tgtaaaacag ctggaaatga gaagatagtt gtcgacatca tggaaaaggc agtcatggag
    86281 atgaggtaat cacgcataaa attcgcgggt tcacctggtg tgtcctgata gataccagaa
    86341 aaaaataaat agaaagccgt cggcatccct accgacaata gataatagat taattgtcgt
    86401 ttggtcaata aaaattctat cttactaagt gctatccatc gtttcatctt agttatctcc
    86461 cttctgcgtc tcttcaaaga ttgtattcaa caaactacga ttattaactt cgatttcttg
    86521 catcctacat cctgcttggg ctaatagttc ccagaaagca tctgcttctc gagtgactac
    86581 ttgtaaagaa tcttgcttta gggtccagtt ttcaaccaaa tttgactgct ctacgacttc
    86641 cttgtaagct ataggaagga taaagtgctt ttctatttcc tcgctacgca tagctagagg
    86701 cgtcgtatct cgaatcaact ctcccttatt taagagcaaa atgcggtctg cagtgtgttc
    86761 cacttcctca atataatggg acgaatagag aatggtgact ccttgcgctt ttaactcctg
    86821 gacaatttcc caaaaacgtt gacgagttga ggtatccatg gacgcagtag gctcatctaa
    86881 aaaaacaatc tttggtcgcc caattaaggt caagacgaaa gaaaagagac gcttttgacc
    86941 gcctgataat ttttctgcca actgttcttt ttgttgcttg acaaactgca atagttgatc
    87001 aatttcctga ttgctcaaag gatttggata gatacgttga aagaaagcaa tcaactcttt
    87061 aacttttaat ttctgaacga ttacattttc ttgagggagg taagccctag tatagtctaa
    87121 cttagaactc gtcactggta aaccttgaat agatacttga ccgcttgtga ccagtttatc
    87181 tccaagcaaa caatctaaga gtgttgtctt tccggcacca tttggaccaa ttaaggcaac
    87241 acattcacca tcgttgattt caaaggagat gttccgcaaa atttccttgt cttttatttt
    87301 cttactcaat ttctcaactt taaccacagt catgagactc tcctttcaac cactccattc
    87361 ccatagggaa aacgacgaaa atcataaatc caaaccccaa agcaccacaa atgaattggc
    87421 gaagcaaggc ttgatcaaac caatcagtaa acatttccac taaccatacc aagagtgaca
    87481 ggccgataaa gaaatagatg atccctctct tcattcttca aactcctttt tcacatctct
    87541 gactaatttc aaaccttctc taacaagcca agacatgatt ccaaagccag caaagacctt
    87601 ccaaggaaaa tggtagaaat cctcatccaa tcccgaaaac atgagatagg tcataactcc
    87661 tgctactact aaactcactg cgataatcat tttatttctc atctcttctt cccccatttc
    87721 atactacaat tatagtcttt taaaatcaga ggaggcagaa gcttctgtca ctagaaaata
    87781 tgacaaatgt cataaaaaat tttgttcaaa acaagcaaga tacactatac aataaaacac
    87841 aatcagaaaa atctaaggca acttcctcaa aagagatatc aaacccaatt cacaccataa
    87901 tgtaaactaa tacttattta aaatcaaaaa gagtagaaat ttttatcaga caaacacata
    87961 tatagtgtat tgaatctata acagtaggcc ttaaatacta aaatatttct ataaattaa
//
LOCUS       DAVHSY010000004        81725 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.004, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000004 DAVHSY010000000
VERSION     DAVHSY010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 81725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81725
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.004"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            1..929
                     /locus_tag="VVR43_000316"
                     /pseudo
     CDS             1..929
                     /locus_tag="VVR43_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            1324..2187
                     /locus_tag="VVR43_000317"
     CDS             1324..2187
                     /locus_tag="VVR43_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU6148734.1"
                     /translation="MIERMELGEFYKELRLARKLKQTDVACEGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMRIGRKVVNRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKDAIHSLNKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFIQSLQVLENPQLTSLFE
                     LRFQQYKELID"
     gene            2478..2675
                     /locus_tag="VVR43_000318"
     CDS             2478..2675
                     /locus_tag="VVR43_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEU6148735.1"
                     /translation="MLNLQFAETMELTEAELETVYGGEFGNNAVIPAGAWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            2743..3408
                     /locus_tag="VVR43_000319"
     CDS             2743..3408
                     /locus_tag="VVR43_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6148736.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFVFYMGGGLIFVVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            3480..4706
                     /locus_tag="VVR43_000320"
     CDS             3480..4706
                     /locus_tag="VVR43_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6148737.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(5102..5179)
                     /locus_tag="VVR43_000321"
                     /pseudo
     CDS             complement(5102..5179)
                     /locus_tag="VVR43_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            5250..5906
                     /locus_tag="VVR43_000322"
     CDS             5250..5906
                     /locus_tag="VVR43_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU6148738.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            5896..6219
                     /locus_tag="VVR43_000323"
     CDS             5896..6219
                     /locus_tag="VVR43_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEU6148739.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            6323..7153
                     /locus_tag="VVR43_000324"
     CDS             6323..7153
                     /locus_tag="VVR43_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6148740.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            7307..8161
                     /locus_tag="VVR43_000325"
     CDS             7307..8161
                     /locus_tag="VVR43_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU6148741.1"
                     /translation="MKIKKWLGLVALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            8261..9634
                     /locus_tag="VVR43_000326"
     CDS             8261..9634
                     /locus_tag="VVR43_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU6148742.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFDPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            9627..10688
                     /locus_tag="VVR43_000327"
     CDS             9627..10688
                     /locus_tag="VVR43_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU6148743.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            10690..11382
                     /locus_tag="VVR43_000328"
     CDS             10690..11382
                     /locus_tag="VVR43_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6148744.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(11412..11981)
                     /locus_tag="VVR43_000329"
     CDS             complement(11412..11981)
                     /locus_tag="VVR43_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU6148745.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            12116..12730
                     /locus_tag="VVR43_000330"
     CDS             12116..12730
                     /locus_tag="VVR43_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU6148746.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            12732..14378
                     /locus_tag="VVR43_000331"
     CDS             12732..14378
                     /locus_tag="VVR43_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6148747.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLNPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRQTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            14390..15676
                     /locus_tag="VVR43_000332"
     CDS             14390..15676
                     /locus_tag="VVR43_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6148748.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATVSHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAEFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKDLFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            15737..16270
                     /locus_tag="VVR43_000333"
     CDS             15737..16270
                     /locus_tag="VVR43_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6148749.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRTAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            16348..16818
                     /gene="nrdI"
                     /locus_tag="VVR43_000334"
     CDS             16348..16818
                     /gene="nrdI"
                     /locus_tag="VVR43_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU6148750.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(17111..18373)
                     /locus_tag="VVR43_000335"
     CDS             complement(17111..18373)
                     /locus_tag="VVR43_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU6148751.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(18683..19141)
                     /locus_tag="VVR43_000336"
     CDS             complement(18683..19141)
                     /locus_tag="VVR43_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU6148752.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(19138..19578)
                     /locus_tag="VVR43_000337"
     CDS             complement(19138..19578)
                     /locus_tag="VVR43_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6148753.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            19934..21883
                     /gene="mutL"
                     /locus_tag="VVR43_000338"
     CDS             19934..21883
                     /gene="mutL"
                     /locus_tag="VVR43_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU6148754.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(22208..22675)
                     /locus_tag="VVR43_000339"
     CDS             complement(22208..22675)
                     /locus_tag="VVR43_000339"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU6148755.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(22676..23881)
                     /locus_tag="VVR43_000340"
     CDS             complement(22676..23881)
                     /locus_tag="VVR43_000340"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU6148756.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRIDDLIQFSKKHNIPLITIKELQEYRKAYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKIIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(23901..24536)
                     /gene="ribE"
                     /locus_tag="VVR43_000341"
     CDS             complement(23901..24536)
                     /gene="ribE"
                     /locus_tag="VVR43_000341"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU6148757.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(24521..25621)
                     /gene="ribD"
                     /locus_tag="VVR43_000342"
     CDS             complement(24521..25621)
                     /gene="ribD"
                     /locus_tag="VVR43_000342"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU6148758.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGSHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMTIDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(25755..25869)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            26026..26619
                     /gene="ruvA"
                     /locus_tag="VVR43_000343"
     CDS             26026..26619
                     /gene="ruvA"
                     /locus_tag="VVR43_000343"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU6148759.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKIAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            26629..27192
                     /locus_tag="VVR43_000344"
     CDS             26629..27192
                     /locus_tag="VVR43_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU6148760.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            27189..27866
                     /locus_tag="VVR43_000345"
     CDS             27189..27866
                     /locus_tag="VVR43_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6148761.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(28003..29034)
                     /locus_tag="VVR43_000346"
     CDS             complement(28003..29034)
                     /locus_tag="VVR43_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEU6148762.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(29289..29972)
                     /locus_tag="VVR43_000347"
     CDS             complement(29289..29972)
                     /locus_tag="VVR43_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU6148763.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(29984..30928)
                     /locus_tag="VVR43_000348"
     CDS             complement(29984..30928)
                     /locus_tag="VVR43_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU6148764.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            complement(31089..32254)
                     /locus_tag="VVR43_000349"
                     /pseudo
     CDS             complement(31089..32254)
                     /locus_tag="VVR43_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704663.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(32339..33853)
                     /locus_tag="VVR43_000350"
     CDS             complement(32339..33853)
                     /locus_tag="VVR43_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEU6148765.1"
                     /translation="MRKYDIPKLLLSGENQGVEFKEAKNSFPKDGMKTICSFANTNNG
                     LLILGVSENTKNKDFYISGVNDPDKVLDELYSLLNNPNKINRNVINEESVEVVNIKGK
                     EIVIIPVNKVDYKDKPIYLNDNIASTYFRQGTGDFRCSQEQINSMLRDSAKESFDSTL
                     IQDFSILDLDTETIKLYREKFDNINAEHPFSKLDNEQFLIKINALRRDRKDDKIKPTV
                     AGLLIFGTHNSIKEFIPHYNVEYVLKEFSENNRFKDRVIYDGTWGEDNLFNFFYLVIE
                     KLYLTLNDNSNIQENSMNRIGISKLRIAIREAFINSLIHSDYKSEKGIMIIRYPDRYI
                     FTNGGTLRIDIKDFFSGAHSDPRNYLIQEIFRFLNLCEKAGTGIPKIMEAVKESHLKY
                     PNLRTELDSVEFTLWDTSLIDNLDIDNEYEKKILELIIEHRFVTREALEEKLKIHKNT
                     ILKYLKKLVEKQAIDKFKSGRQYVYFITQNQDPEFQKYNHINAMYSLLEEIKRK"
     gene            complement(34014..34727)
                     /locus_tag="VVR43_000351"
     CDS             complement(34014..34727)
                     /locus_tag="VVR43_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6148766.1"
                     /translation="MAKNSPQDLKNREYFSNNLNRVMKEKGIRQIDLHNALEIPKSTI
                     TGYVKGRSMPTSGNLQKLADYLGVKKSDLDPRFSDKDVYKEFLYMLDKQLDEEKYLVK
                     NVSKDKIFQKVKEREKRDKEIIELAKSKNFPISPEEFLTTITESLNEYNPKDNYEVLN
                     ALALKTSNILFWLDIVFQKTSSEFYIVFEDKEFNQEYYNKLYKKFENLFEEIKSLALQ
                     EAKKDKENLDDFALLWGID"
     gene            34880..35110
                     /locus_tag="VVR43_000352"
     CDS             34880..35110
                     /locus_tag="VVR43_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6148767.1"
                     /translation="MAQWTLRACRVNAGFTLRQVAKKVNKNFQTISKYEKDSTLIPFE
                     LLKELSELYQVKLDDIFLGDSTKKIELNQKEI"
     gene            35126..35752
                     /locus_tag="VVR43_000353"
     CDS             35126..35752
                     /locus_tag="VVR43_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEU6148768.1"
                     /translation="MELVYMDGKKEPYTLSSIVAECAEVKHRHLKILLNKHREDFESF
                     GKVQFKISPSESGQNVRDYILNEQQATLLITYLRNTEPVKEFKKNLVKAFFEMREELS
                     KFRMQRALEKPKRKTLHDSIETWEAKPKHAHSTMNNLLLKAVTDMNAKQLREERGGYN
                     GIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSA"
     gene            36124..36576
                     /locus_tag="VVR43_000354"
     CDS             36124..36576
                     /locus_tag="VVR43_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148769.1"
                     /translation="MTETTYENLTRHIDRISAEMREIGEKNGLSRLSLLANQTKFIKE
                     NLHRLLWIELPELNDSHKIEAVSKSTTGMFFHAGIFEMDAMRQAFFKRQAMHFFDNEA
                     EQQAYIEHAEKEYLEATITLKDILFNSKNGTQRVNKSCLIEKFEEAMQ"
     gene            36573..36773
                     /locus_tag="VVR43_000355"
     CDS             36573..36773
                     /locus_tag="VVR43_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148770.1"
                     /translation="MTLNLDNMTQAEFDEVMAEIKEKRPNLFQFIADFVDRKVSTEEV
                     DEYLKMKHEKQVEFIKNYQARA"
     gene            36775..36990
                     /locus_tag="VVR43_000356"
     CDS             36775..36990
                     /locus_tag="VVR43_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148771.1"
                     /translation="MNELDLTNTQSVIFMVVLIGLLLYLNHRDRKKSAQFERENQQRI
                     ETPSEDLSPDYGRYIQLAGVRVYGGTE"
     gene            36987..37328
                     /locus_tag="VVR43_000357"
     CDS             36987..37328
                     /locus_tag="VVR43_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU6148772.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGAEISLITKLAERTVQDIISR
                     LITRHSVPIVGVRHGTFRGYFIPANKEELLDGAKAFYNQVQEEQKRLTVLLNADLESY
                     KETLKEVGGYV"
     gene            37321..37602
                     /locus_tag="VVR43_000358"
     CDS             37321..37602
                     /locus_tag="VVR43_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU6148773.1"
                     /translation="MFSLSRESEQDLAHGILEVVERYLEARDTVKPRLTGLISAQEVM
                     DELDIKYMTLQKWEKAGLRRYQPPLEDTRKIYYKISDIWKFLGVENGKV"
     gene            37737..38603
                     /locus_tag="VVR43_000359"
     CDS             37737..38603
                     /locus_tag="VVR43_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEU6148774.1"
                     /translation="MTIYEAKGFQSNLVYPFDKIEPFQYIERFKPLVVPEGADIEEYK
                     RTQAPYCISGKVTPEKHGSYKRNNSSLIYRDLIFLDYDDIQGTSEGFIKAISSALFGY
                     SYILYPTIKHSLEKPRFRLVVKPDNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPASYQKIVEHGLDYPVPQTTAEPVKQNAASLPYTPRPSGQKSMTMRIIDT
                     LFNGFGDEGGRNVALTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTF
                     SSIARAEYRKRG"
     gene            38656..40125
                     /locus_tag="VVR43_000360"
     CDS             38656..40125
                     /locus_tag="VVR43_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HEU6148775.1"
                     /translation="MEQEHPPRTMKELENRIFKAGEEWRAEHTETKVNENTGDVTEKV
                     AMPQTFTVAKILSEIVTFTFISKSNIPDYSLLYIYDLDEGIYTASNDLFNLLCKTFDV
                     RIKPREWPQIKLMVRTLAKIRKPLESANLIPVQNGIINLETKELLPFSPKYVITSKIS
                     TAYHAPKRVPTDREGKTFDDWLNSIACNDSELVTLFWQIILEAIDPNHTRNKFAIFYG
                     DGNNGKGTFQRFLINLIGESNISALKPAQFAEKHNLETLVGKVCNIGDEAPNEYLKNP
                     SDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGNKTKGWYRRIMIVPFNA
                     DFNGEKEKPWIKNEFLANKEVLEYALYKAINQEPFTHFIEPKAVKGLLEEYQEDNDYL
                     LSWVKHEYMEKGWHELDVVPVFIVTRSLKHYAEDMGIPKPNVYGAGKETIKHLQQLTP
                     NRYSLRKKRVSPEDFEKLEAWDVDKIKMRTPQHSITKQE"
     gene            40478..40645
                     /locus_tag="VVR43_000361"
     CDS             40478..40645
                     /locus_tag="VVR43_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148776.1"
                     /translation="MKVKLFEYTRRWEKEDFEKEIDDFMATVEVLDVKFSGTPSSESF
                     NSVAIVLVLYR"
     gene            40729..41259
                     /locus_tag="VVR43_000362"
     CDS             40729..41259
                     /locus_tag="VVR43_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148777.1"
                     /translation="MTLKTFSSKAKTFTFTYEFKDLDTALVAGHALLGYMTGTYCQPV
                     ISLTYKDKGTLVAEYVEDHKLNKTFKRICDSFKDYHKQPGEAEAFEERYKRERVLQLK
                     ESEDFESLLNKVTDYELELLDYADRLLSDKPIPMDSMTAFATLEMLGDESISLLQKLD
                     VEGEYKGLAGYTEHLK"
     gene            41330..41839
                     /locus_tag="VVR43_000363"
     CDS             41330..41839
                     /locus_tag="VVR43_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148778.1"
                     /translation="MKQLAIEAITKPMKLRGISKGIAELDGQRLEIDLDSLMIDFGGE
                     SFELDRIAGTKGGNRYFFLCPDCGRRCRLLYKRYLYFSCGTCLDIHKHTLNRSKTDCQ
                     YYWELALKEARKVEPGWSPRRGGYMFDSFPERPKYMKQKRYYKHYQKFINYTRKGDSF
                     WLNGLSSLR"
     gene            43035..43454
                     /locus_tag="VVR43_000364"
     CDS             43035..43454
                     /locus_tag="VVR43_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEU6148779.1"
                     /translation="MTPEQVKEKLEGVKWINKEIKGLYLELETLEGGIIKKPTLSHSR
                     VQTSRENKTENNLISVLKLKEDTLQRIERLTEERMKISELIDKLANPLERSVLRLFYL
                     NDLVVSEVAEEIDRSNTTVYIIRQKAIEHLTGIVNGD"
     gene            43943..46774
                     /gene="uvrA"
                     /locus_tag="VVR43_000365"
     CDS             43943..46774
                     /gene="uvrA"
                     /locus_tag="VVR43_000365"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU6148780.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            46767..47828
                     /locus_tag="VVR43_000366"
     CDS             46767..47828
                     /locus_tag="VVR43_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU6148781.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            47960..48358
                     /gene="spx"
                     /locus_tag="VVR43_000367"
     CDS             47960..48358
                     /gene="spx"
                     /locus_tag="VVR43_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU6148782.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            48424..48993
                     /locus_tag="VVR43_000368"
     CDS             48424..48993
                     /locus_tag="VVR43_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU6148783.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            49080..49346
                     /locus_tag="VVR43_000369"
     CDS             49080..49346
                     /locus_tag="VVR43_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU6148784.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            49350..49769
                     /gene="ruvX"
                     /locus_tag="VVR43_000370"
     CDS             49350..49769
                     /gene="ruvX"
                     /locus_tag="VVR43_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU6148785.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            49785..50090
                     /locus_tag="VVR43_000371"
     CDS             49785..50090
                     /locus_tag="VVR43_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU6148786.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            50348..51598
                     /locus_tag="VVR43_000372"
     CDS             50348..51598
                     /locus_tag="VVR43_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU6148787.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            51595..52137
                     /locus_tag="VVR43_000373"
     CDS             51595..52137
                     /locus_tag="VVR43_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU6148788.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            52283..53815
                     /gene="cls"
                     /locus_tag="VVR43_000374"
     CDS             52283..53815
                     /gene="cls"
                     /locus_tag="VVR43_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU6148789.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            54073..55611
                     /locus_tag="VVR43_000375"
     CDS             54073..55611
                     /locus_tag="VVR43_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU6148790.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTNQGDQAGQLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVEVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            55731..57938
                     /gene="nrdD"
                     /locus_tag="VVR43_000376"
     CDS             55731..57938
                     /gene="nrdD"
                     /locus_tag="VVR43_000376"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU6148791.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            57950..58090
                     /locus_tag="VVR43_000377"
     CDS             57950..58090
                     /locus_tag="VVR43_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148792.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            58134..58640
                     /locus_tag="VVR43_000378"
     CDS             58134..58640
                     /locus_tag="VVR43_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6148793.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVER
                     YWIEVANE"
     gene            58633..59223
                     /gene="nrdG"
                     /locus_tag="VVR43_000379"
     CDS             58633..59223
                     /gene="nrdG"
                     /locus_tag="VVR43_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU6148794.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGILYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            59220..59837
                     /locus_tag="VVR43_000380"
     CDS             59220..59837
                     /locus_tag="VVR43_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEU6148795.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            60103..60411
                     /gene="rpsJ"
                     /locus_tag="VVR43_000381"
     CDS             60103..60411
                     /gene="rpsJ"
                     /locus_tag="VVR43_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU6148796.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            60628..61254
                     /gene="rplC"
                     /locus_tag="VVR43_000382"
     CDS             60628..61254
                     /gene="rplC"
                     /locus_tag="VVR43_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU6148797.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            61279..61902
                     /gene="rplD"
                     /locus_tag="VVR43_000383"
     CDS             61279..61902
                     /gene="rplD"
                     /locus_tag="VVR43_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU6148798.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            61902..62198
                     /locus_tag="VVR43_000384"
     CDS             61902..62198
                     /locus_tag="VVR43_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU6148799.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            62216..63049
                     /gene="rplB"
                     /locus_tag="VVR43_000385"
     CDS             62216..63049
                     /gene="rplB"
                     /locus_tag="VVR43_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU6148800.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            63153..63434
                     /gene="rpsS"
                     /locus_tag="VVR43_000386"
     CDS             63153..63434
                     /gene="rpsS"
                     /locus_tag="VVR43_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU6148801.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            63446..63790
                     /gene="rplV"
                     /locus_tag="VVR43_000387"
     CDS             63446..63790
                     /gene="rplV"
                     /locus_tag="VVR43_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU6148802.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            63803..64456
                     /gene="rpsC"
                     /locus_tag="VVR43_000388"
     CDS             63803..64456
                     /gene="rpsC"
                     /locus_tag="VVR43_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU6148803.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            64460..64873
                     /gene="rplP"
                     /locus_tag="VVR43_000389"
     CDS             64460..64873
                     /gene="rplP"
                     /locus_tag="VVR43_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU6148804.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            64883..65089
                     /locus_tag="VVR43_000390"
     CDS             64883..65089
                     /locus_tag="VVR43_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU6148805.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            65114..65374
                     /gene="rpsQ"
                     /locus_tag="VVR43_000391"
     CDS             65114..65374
                     /gene="rpsQ"
                     /locus_tag="VVR43_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU6148806.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            65400..65768
                     /gene="rplN"
                     /locus_tag="VVR43_000392"
     CDS             65400..65768
                     /gene="rplN"
                     /locus_tag="VVR43_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU6148807.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            65846..66151
                     /gene="rplX"
                     /locus_tag="VVR43_000393"
     CDS             65846..66151
                     /gene="rplX"
                     /locus_tag="VVR43_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU6148808.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            66175..66717
                     /gene="rplE"
                     /locus_tag="VVR43_000394"
     CDS             66175..66717
                     /gene="rplE"
                     /locus_tag="VVR43_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU6148809.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            66735..67004
                     /gene="rpsN"
                     /locus_tag="VVR43_000395"
     CDS             66735..67004
                     /gene="rpsN"
                     /locus_tag="VVR43_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU6148810.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            67289..67687
                     /gene="rpsH"
                     /locus_tag="VVR43_000396"
     CDS             67289..67687
                     /gene="rpsH"
                     /locus_tag="VVR43_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU6148811.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            67879..68415
                     /gene="rplF"
                     /locus_tag="VVR43_000397"
     CDS             67879..68415
                     /gene="rplF"
                     /locus_tag="VVR43_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU6148812.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            68499..68855
                     /gene="rplR"
                     /locus_tag="VVR43_000398"
     CDS             68499..68855
                     /gene="rplR"
                     /locus_tag="VVR43_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU6148813.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            68873..69367
                     /gene="rpsE"
                     /locus_tag="VVR43_000399"
     CDS             68873..69367
                     /gene="rpsE"
                     /locus_tag="VVR43_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU6148814.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            69339..69563
                     /gene="rpmD"
                     /locus_tag="VVR43_000400"
     CDS             69339..69563
                     /gene="rpmD"
                     /locus_tag="VVR43_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU6148815.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            69708..70148
                     /gene="rplO"
                     /locus_tag="VVR43_000401"
     CDS             69708..70148
                     /gene="rplO"
                     /locus_tag="VVR43_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU6148816.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            70161..71471
                     /gene="secY"
                     /locus_tag="VVR43_000402"
     CDS             70161..71471
                     /gene="secY"
                     /locus_tag="VVR43_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU6148817.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            71622..72260
                     /locus_tag="VVR43_000403"
     CDS             71622..72260
                     /locus_tag="VVR43_000403"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU6148818.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            72377..72595
                     /gene="infA"
                     /locus_tag="VVR43_000404"
     CDS             72377..72595
                     /gene="infA"
                     /locus_tag="VVR43_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU6148819.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            72620..72736
                     /gene="rpmJ"
                     /locus_tag="VVR43_000405"
     CDS             72620..72736
                     /gene="rpmJ"
                     /locus_tag="VVR43_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU6148820.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            72754..73119
                     /gene="rpsM"
                     /locus_tag="VVR43_000406"
     CDS             72754..73119
                     /gene="rpsM"
                     /locus_tag="VVR43_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU6148821.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            73137..73520
                     /gene="rpsK"
                     /locus_tag="VVR43_000407"
     CDS             73137..73520
                     /gene="rpsK"
                     /locus_tag="VVR43_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU6148822.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            73563..74498
                     /locus_tag="VVR43_000408"
     CDS             73563..74498
                     /locus_tag="VVR43_000408"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU6148823.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            74510..74896
                     /gene="rplQ"
                     /locus_tag="VVR43_000409"
     CDS             74510..74896
                     /gene="rplQ"
                     /locus_tag="VVR43_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU6148824.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            75161..75427
                     /locus_tag="VVR43_000410"
     CDS             75161..75427
                     /locus_tag="VVR43_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU6148825.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            75437..76774
                     /locus_tag="VVR43_000411"
     CDS             75437..76774
                     /locus_tag="VVR43_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU6148826.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            77018..77710
                     /locus_tag="VVR43_000412"
     CDS             77018..77710
                     /locus_tag="VVR43_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU6148827.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(77813..79448)
                     /locus_tag="VVR43_000413"
                     /pseudo
     CDS             complement(77813..79448)
                     /locus_tag="VVR43_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(79438..80529)
                     /locus_tag="VVR43_000414"
                     /pseudo
     CDS             complement(79438..80529)
                     /locus_tag="VVR43_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(80542..81663)
                     /locus_tag="VVR43_000415"
                     /pseudo
     CDS             complement(80542..81663)
                     /locus_tag="VVR43_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
BASE COUNT        24908 a        15131 c        17610 g        24076 t
ORIGIN      
        1 ccgacagatt atgatgagaa aattggtagt tttaatacat atgaaatcga acaaacggta
       61 tcgaagattc tgagggtaaa acctaatgga aagattattt taaagtcaac agttccgatc
      121 ggcttttcaa acaaattaaa aaggctgttt gatacaaaaa atatcatttt tgtccctgaa
      181 tttttgagag aaggttgttc tatatatgat aatttatatc caagtcgcat agttgttgga
      241 gatgagacag ttgaaggaag aaaaattgca gagttgttcc tttcgattag tactcatagt
      301 actgccaata ttaaaaatgt tatgttagtt tctcctactg aagcagaagc aattaagctt
      361 ttttctaaca cattcttagc tctccgtgtt gcttttttaa tgaactagat tcttttgctg
      421 agaggagaag cttaaatgct gaagttgtaa taaaaggtgt ttgtttagat ccaagaattg
      481 gaaattttta taataatcct tcttttggat ttggaggata ttgtcttccc aaagatacta
      541 aacaattaaa aaaagaattt atagaaataa atgccccagt gatagaagcg attgatattt
      601 caaacacaaa tagaaaacag ttcatagtta aacaaatatt ggaacgaaag ccaaagatag
      661 taggaatata taaattgggg atgaaatata attcagataa ttacaaagag tcagctattt
      721 taagtataat taatgaacta ttgattgtcg gtataaaaat tttagtatat gaaccaaatt
      781 taaacgttag tatagataac gtaattattg aaaagaattt tgaactattt acaaaacaaa
      841 gtgatctaat tgttgcaaat agatgggata ggggccttga agcttataaa gataaagttt
      901 acacaagggg gatctggata agagattaac tattgatatt aaaaaggcaa taatttataa
      961 aatttgtaca aaaaaatgtt aaattttcac attttcatag tatactgttt aatagaaagt
     1021 aggttctttg taaccgctcc attataaaat cctttcactc ttccggtata ctattaggaa
     1081 aaacataact ggaggatatt ttgagctcac acctcatcgt tccagtggct gttccccaag
     1141 ctcgtgtact gcccaaaaaa gttagacatt ctatttagaa cgaggattga gttctgtatt
     1201 gtacaaggct cggtcctttt agagtcagct taaggctggc ttttttgccc tcttaaatat
     1261 cagaatattt tgacaaatga ttgtaaataa tgatataata tgcaaaagct aggaggtggt
     1321 cagatgattg agagaatgga actgggggaa ttttacaagg aattacgttt ggcgagaaag
     1381 cttaagcaga cagatgtggc ttgtgagggt ctaacagctt ctcagttgtc caagtttgaa
     1441 ctagggcagt ctatgctgtc tgcggataag ttgattctag ctatccaagg tataaatgtg
     1501 acctttgatg agtttgggca caagctcaac aactatcaag aatctccaca tatgcgaatc
     1561 ggtcgaaagg ttgtgaatcg ctttgcccat caggatatag ctgctttaga gcagctattg
     1621 gaggaagtcg atcaagaaca gatggcgcag acctatcgtc gtttgaatgc catcgtgatt
     1681 aaagatgcca tccattcact aaataaaagc tacccactag cagaggagga tagcgagttt
     1741 ttgaccacct atctctatgc tatcgagtct tggacctggt ttgaactcta tctcttttgc
     1801 aataccatgc ccttcttgag caatcaagat ctgatttttt tatcaacctc cttactcgaa
     1861 aaatccaaag aatttaaaga gttagtacac aatcgattgt atatgaagca aggactctta
     1921 aatatcttat cagaactcat ggagcgaaaa cttttctcct acatcccaat cttcgaagcc
     1981 gagttggaga ggatgttacg accgtatgat gtttttgaaa aagtatcgtg gcaattttta
     2041 aagaagatga gtgtctttct tcaaacaaag ggaagcaatc aaaaagagat tgaacgcttt
     2101 atccaatctc tgcaggtatt agaaaatcca caattaacat ccctttttga attgcgtttt
     2161 cagcaatata aagaacttat agattagtta aaaatggaat gacaataacc cactccgaaa
     2221 taagtaggag tatcggttgg atttttcttt tcttcatcta ttatattcct ccttgttagt
     2281 aataacttta ttataccagg gaaataatca aatctatcaa aatcgcaaat aagaaatttc
     2341 tataagaaaa aatatcaaat atgcgatttt ttaaaataag ccaattttcg tgttatactg
     2401 tacttgtaaa gcacttgaag caaatcctag gtcgcagaag tggtttacaa atgaagataa
     2461 ttgaaggagt gtaaaagatg ttaaatttac aatttgcaga aacaatggaa ttgacagaag
     2521 ctgagttgga gacagtttat ggaggggaat ttgggaataa tgctgttatc ccagccggtg
     2581 cttggggagg tttaggaacg tcttggtcaa tcactaattt ctggaagaaa tattttaacc
     2641 atgattcttc cactgttaat cgtcgccatt attgatattc agagtccttg cctttttctt
     2701 gggtagggac tgtctttatt tcatagtata ggagaaaata gaatgaaaaa gataatctca
     2761 caccgctact ttattatagt ttttctacta gttattgctg accagaagtt cagtgttcta
     2821 gttttacgca gcgaccttgt tactgggcta tctgactttg cctattatct gtcggatatg
     2881 atgttgaatt ttcttgtggt tttatttgct cttattgcta tgatttggtc ggggaaatgg
     2941 cagaaaatca atagtagaaa gtttaaagga tcctatcttt tctattcctt cctagctctg
     3001 cttgcttttg ttgtttggaa tttcgttacc ttttttcttt tcccacctac tcgaaatgaa
     3061 atttcttatc aacatgctgc tccgactttt acaggggcta cagcattttt gatgtatttt
     3121 ttctatcctg tgattgcagg tcccattttt gaagagataa tccatcgggg attggtgatg
     3181 acagctctgg aaaaaggaaa gaaatggggg ctagatgtac ttggttctgc tattttattt
     3241 ggggtctcgc acattagtaa tcacggttgg gtcttgacag actttgtctt ctatatgggt
     3301 ggcggactta tatttgtagt cttatttaga atgacaaagt ccatttattg gcctattggg
     3361 ctgcatatag tctacaacgg cattggtcag cttttgatgt tactgtaatt ttggttgtta
     3421 gtagtatcgc ggtctattct tggggaaaga ttcccatttg aatttaaaaa ggagttgtaa
     3481 tgaaagtatt tcttcaaaat agagatttta ggcaattaac tatcaaccag tggatttcaa
     3541 cgcttgggga tacgattttt tatctggcct tcctgaatta tgtggcagat gcgtcttttg
     3601 cccctttggc gattttactt atcacgattt cagaaaccct tccccaagtt ctacaaatct
     3661 ttctgggagt tttggcggat tttcaacatc atcgtgtctt gaaatacaca gtcattagtt
     3721 ttacaaaatt tttgctttac tctatagtgt ccctatcgct ttcagggcag tctttttcct
     3781 tgttgctagt aacctttatt tgtctgatta acctcttgtc tgacacattg agttactttt
     3841 caggagccat gctcactccg attttcatta gaattattgg gcaagaccat ctggcagaag
     3901 ctattggatt taaacagtca actgttagtt tagtgaaaac aatcagtaat attctaggag
     3961 gagtcttgct agggattctc tccatccagt tcatttcctt gctgaacgct cttacctttt
     4021 taatcgcatt tttaggtatc ctcttcataa aaactgacct cttgaaagta gaaaaaacga
     4081 ttaactatca agaaggactc tctgtaaaat ccttttgcca gcatttgctc caatcatcga
     4141 aattgatatg gaatatgaat aaggtgctct tggttttgtt tattatctct actagtcaag
     4201 cagtgataaa tgttacagtt cctgtctcta ctctattttt gaggaatcaa ccctttttga
     4261 atttacaaac aggtcaatct cttgccttgc tatccacttt tgaactgtca gccctgattg
     4321 tcggaagcct tgtaagtggc tatctgcaac ataccatttc cataaaaaca gctctctatg
     4381 cctcacttgt catccagttg cttcttctag taggatttgc cacagttcgt tttgactgga
     4441 ttctcatctt tagtaccttg gatgcctttt tcgcaggtgt tctctctcct agattgcaag
     4501 aactcgtctt taaacaaata cctgaggagt caatgggagc agttcaatcc tctatcggtg
     4561 ccattacggt tgttttacct agcttattta caatagcttt ggtaaccatt gctactagct
     4621 ttggaactct ggcagttagc tttgttttat tgctatttct tctagttgcc tttgttatgc
     4681 ttctgaatat tcgtgaaagt atttagtgga gaatttctat aatatatgtt tgagactgga
     4741 ttgccagtct ttttatgatg gtcaaaatca acagactttt ttctcttttc tgaatgtgtt
     4801 ataatagact gaatctaaaa tagtacgaaa caattgctaa aacatttata gaaattaatt
     4861 ttactttccc aatcgatttg ttctcatctt atttcaatct gctatataat agtccatgct
     4921 gtggctggat tcttttcagc ctacttatac tcttcgaaac tctcttcaaa ccacgtcagc
     4981 ttcactttgc cgtatatatg ttactgactt cgtcagttct atccacaacc tcaaaacggt
     5041 gttttgagct gacttcgtca gttctatcca caacctcaaa acggtgtttt gagctgactt
     5101 cgtcagttct atccacaacc tcaaaacagt gttttgagca acctgcggct agtttcctag
     5161 tttgctcttt gattttcatt gagtattatt aagacaatat gaggagaaag atgaaagaaa
     5221 aaggatttta ggagggggcg caggcagcca tgccaacggc tcttggctat gtcagtatcg
     5281 gcctggcctg tgggactatc ggtgcgccct atgtgacacc tgttgagatg ggcttgatga
     5341 gtctctttgt ttatgctggg agtgcccagt ttgccatgtt ggcactgatt gtggttcaag
     5401 ctcctgtggc agctattgct atgacggttt ttctaatcaa cttgcgtctc tttttgttga
     5461 gtttacacgc atcgacttat ttccgtcata ccagtctttg gtacaatatc ggtatgtcta
     5521 gtatcttgac agatgagacc tatggcgttt tgatgggtga attggcccat acagacaagg
     5581 taaatcctat gtggatgcac ggaaacaatc ttaacagcta tgtggcttgg tttgtgggga
     5641 cagtagtcgg aacggctctg ggtggcctgc taccaaatcc agaaatcttt ggcttggatt
     5701 ttgccctggt tgggatgttt attggtattt ttgcttcgca atttcagatt atgcaaagac
     5761 ggattcctgt ccgcaatctg ctcattatcc tagcagttgt tgcggtgtcc ttctttttgc
     5821 tcttgacagt ggtgtctcag tcactagctg ttctgtttgc gacgctactt ggttgtagca
     5881 tgggggtggt tttagatggt cagtaagtat cttttattag cagttatttt ctctggcttg
     5941 gtgacttgga ttctccgtat gattcccttc atcttagtca agtataaggg cttgcctgca
     6001 atcgttgagc gttttttgaa gttcttgccc gtttccatta tctttgcctt gattctttca
     6061 agcgtagtga caggtaaggt tgggagcctt cctcaaatta aatggctaga cttcttagcc
     6121 gtctttccaa cagcttgggt agcctttcgc taccgcaatc tagtcggaac agttctcttt
     6181 ggagtggtct tgattgccat cttgcgtttg gtcttttaaa ttacccataa aaaaaactta
     6241 tcacagagat agatatcata taatggcgta aatgctcttt ttctgttaag attataaggt
     6301 attctatttt ggaggaaatg acatgaaaaa aatcgttaaa tactcatctc ttgctgccct
     6361 aggacttgtt gctgcaggtg tgcttgcggc ttgctcaggg ggtgctaaga aagaaggaga
     6421 agcagctagc aagaaagaaa tcatcgttgc aaccaatgga tcaccaaggc catttatcta
     6481 tgaagaaaat ggcgaattga ctggttacga gattgaagtc gttcgcgcta tctttaaaga
     6541 ttctgacaaa tatgatgtca agtttgaaaa gacagaatgg tcaggtgtct ttgctggtct
     6601 tgacgctgac cgttacaata tggctgtcaa caatcttagc tacactaaag aacgtgcgga
     6661 gaaatacctc tatgccgcac caattgccca aaatcctaat gtccttgtcg tgaagaaaga
     6721 tgactctagt atcaagtctc tcgatgatat cggtggaaaa tcgacggaag tcgttcaagc
     6781 cactacatca gctaagcagt tagaagcata caatgctgaa cacacggaca acccaactat
     6841 ccttaactat actaaggcag acttccaaca aatcatggta cgtttgagcg atggacaatt
     6901 tgactacaag atttttgata aaatcggtgt tgaaacagtg atcaagaacc aaggtttgga
     6961 caacttgaaa gttatcgaac ttccaagcga ccaacaaccg tacgtttacc cacttcttgc
     7021 tcaaggtcaa gatgagttga aatcatttgt agacaaacgc atcaaagaac tttataaaga
     7081 tggaactctt gaaaaattgt ctaaacaatt cttcggagat acttatctac cagcagaggc
     7141 tgatattaaa taatttcttg aaatcatcca ttctgagtaa gatgggtgat ttctcagttt
     7201 ttagggatat agttttaaac tatatatctg attatctaat aacaatttgt gaaatcaaac
     7261 aaattgtgag atactagtac ggtattattt ttaaggagaa agaatcatga aaatcaaaaa
     7321 atggcttggc ctagtagccc ttgctacagt cgcaggtttg gctcttgcag cttgcggaaa
     7381 ctcagaaaag aaagcagaca atgcaacaac tatcaaaatc gcaactgtta accgtagcgg
     7441 ttctgaagaa aaacgttggg acaaaatcca agaattggtt aaaaaagacg gaattacctt
     7501 ggaatttaca gagttcacag actactcaca accaaacaaa gcaactgctg atggcgaagt
     7561 agatttgaac gctttccaac actataactt cttgaacaac tggaacaaag aaaacggaaa
     7621 agaccttgta gcgattgcag atacttacat ctctccaatc cgcctttact caggtttgaa
     7681 tggaagtgcc aacaagtaca ctaaagtaga agacatccca gcaaacggag aaatcgctgt
     7741 accgaatgac gctacaaacg aaagccgtgc gctttacttg cttcaatcag ctggcttgat
     7801 taaattggat gtttctggaa ctgctcttgc aacagttgcc aacatcaaag aaaatccaaa
     7861 gaacttgaaa atcactgaat tggacgctag ccaaacagct cgttcattgt catcagttga
     7921 cgctgccgtt gtaaacaata ccttcgttac agaagcaaaa ttggactaca agaaagcact
     7981 tttcaaagaa caagctgatg aaaactcaaa acaatggtac aacatcattg ttgcgaaaaa
     8041 agattgggaa acatcaccta aggctgatgc tatcaagaaa gtaatcgcag cttaccacac
     8101 agatgacgtg aaaaaagtta tcgaagaatc atcagacggt ttggatcaac cagtttggta
     8161 ataagaaaca gggaggtggg agagagaatt ccacctcttg cttttgtata gagcacggag
     8221 tgtaaagaag actattcgtt catagaaagg tagagagaat atggtttttc ctagcgaaca
     8281 agaacagatt gaaaaatttg aaaaggatca tgtagcccag cattattttg aggttttgcg
     8341 taccttgatt tctaagaaat cagtctttgc ccagcaggtt ggactcaagg aagtcgcaaa
     8401 ttatctgggt gagattttca agcgtgttgg agctgaagtg gagattgatg agagctatac
     8461 agcgcccttt gtcatggcac atttcaagag ttcgcgtcca gatgccaaga ccttgatttt
     8521 ctataaccac tatgacactg tgccagcgga tggggatcag gtctggacag aggatccttt
     8581 tacgctttcg gtccgcaatg gcttcatgta tgggcgtgga gttgatgacg acaagggtca
     8641 tatcacagct cgcttgagtg ctttgagaaa atatatgcag caccatgatg atttacctgt
     8701 caatatcagc tttatcatgg agggagcgga ggaatcggct tcaacagacc tagataagta
     8761 tttggaaaag catgcagaca aactccgtgg ggcggatttg ttggtctggg aacaagggac
     8821 caaaaatgcc ttggaacagc tggaaatttc tggtggcaat aaggggattg tgacctttga
     8881 tgccaaggta aaaagcgctg atgtggatat ccactcgagt tatggtggtg ttgtggaatc
     8941 agctccttgg tatctcctcc aagccttaca gtctcttcgt gctgcggatg gccgtatctt
     9001 ggttgaaggc ttgtacgaag aagtacaaga gcccaatgaa cgagaaatgg ccttgctaga
     9061 aacttatggt caacgaaacc cagaggaagt tagtcggatt tatggattgg agttgcctct
     9121 cttacaggag gagcggatgg cctttctaaa acgtttcttt ttcgatccag cgcttaatat
     9181 cgaaggaatc cagtctggtt atcaaggtca gggtgttaag actattttac ctgcagaagc
     9241 cagtgccaag ctagaggttc gtctggttcc gggcctagaa ccgcatgatg ttctggaaaa
     9301 aattcggaaa cagctagaca aaaatggctt tgataaggta gaattatact ataccttggg
     9361 agagatgagc tatcgaagcg atatgagcgc accagccatt ctcaatgtga tcgagttggc
     9421 caagaaattc tatccacagg gcgtttcagt cttgccgacg acagcgggga caggacctat
     9481 gcatacggtc tttgatgccc tagaggtacc aatggttgca ttcggtctag gaaatgccaa
     9541 tagccgagac cacggtggag atgaaaatgt gcgaatcgct gattattaca cccatatcga
     9601 attagtagag gagctgatta gaagctatga gtagagatat tatcaagtta gatcagatcg
     9661 atgtgacttt tcaccaaaag aagagaacca tcacagcggt taaggatgtg accattcaca
     9721 tccaagaagg ggatatctac ggaatcgttg gatattctgg agcaggaaaa tcaacccttg
     9781 tacgggtgat taatcttttg caaaaaccat ctgcagggaa aattaccatt gacgacgatg
     9841 tgatttttga cggcaaggtg accttgacgg cagagcagtt gcgtcgtaaa cgtcaagata
     9901 tcgggatgat tttccagcat tttaacctga tgagccaaaa gacagcagag gagaatgtag
     9961 cctttgccct taaacactct ggactcagca aggaagaaaa gaaggctaaa gtagctaagt
    10021 tgttggactt ggttggtttg gcagatcgtg ctgaaaacta cccttcacaa ctatctggag
    10081 ggcaaaaaca gcgtgtggca attgcgcgtg ccttggccaa tgatccaaaa atcttgattt
    10141 cagacgagtc aacttctgcc cttgacccta agacaaccaa gcagattttg gccttgttgc
    10201 aagatttgaa ccaaaaatta ggattgacag ttgtcttgat tacgcatgaa atgcagattg
    10261 tcaaagacat tgccaaccgt gtggcggtta tgcaggatgg gcatttgatt gaagagggaa
    10321 gtgtccttga aatcttctca aaccctaaac aacctttgac tcaagacttt atctcaacag
    10381 ccacaggtat tgacgaagcc atggtcaaaa tcgagaagca agaaatcgtg gaacacttgt
    10441 ctgaaaacag tctcttggtg caactcaagt acgctggagc ttcaacagac gagccacttt
    10501 tgaatgaatt gtacaagcat taccaagtaa tggctaatat tctctatggg aatatcgaaa
    10561 ttctcgatgg tactcctgtt ggagaattgg tggtggtctt gtcaggtgaa aaagcagcgt
    10621 tggcaggtgc ccaagaagcc attcgtcaag caggtgtaca actaaaagta ttgaagggag
    10681 tacagtaaga tggaatcatt gattcaaacc tatttaccaa atgtctataa aatgggttgg
    10741 gctggtcagg caggctgggg aacggctatc tacttaactc tttatatgac agttctttcc
    10801 ttcattatcg gaggcttctt ggggctagtg gcaggtctct ttctcgtctt gacagcgcca
    10861 ggtggtgtct tggagaataa agtcgtattc tggattttag acaaaattac ctcaattttt
    10921 cgtgcggttc cctttatcat cctcttggca atcttgtcac cactttctca cttgattgtt
    10981 aaaacaagta tcgggccaaa tgcagccctt gtcccacttt cttttgcagt ctttgccttc
    11041 tttgcccgtc aggtgcaggt tgtcttggct gaattggatg gcggtgtcat tgaggcggct
    11101 caagcgagcg gagcgacttt ctgggacatc gtgggtgttt acctatcaga aggtcttcca
    11161 gatttgatcc gtgtgacgac tgtgaccttg atttcccttg ttggggaaac agctatggcc
    11221 ggtgcggttg gagctggtgg tatcggtaac gtagccatcg cttatggatt taaccgctac
    11281 aatcacgatg tgaccatctt ggcaaccatt attatcattt tgattatctt tgcaatccaa
    11341 ttcttgggag atttcttgac taagaaattg agccataaat aaaaaagagc cgcgtggctc
    11401 tttttaactg atcagatttt ctgtgcaaat tttttactca aggcttgtcc aatcaaggca
    11461 cccactaggg ctccgatgac aatacttgcg ataaatagaa ggacagttcc agggtttgga
    11521 gcgaccatga tacggtcgat atattcttgg gattttcctc ttgccagaag agtagccata
    11581 taggctttgg gcgcaatcca cataagcaag attggtcctg ttgtactaaa ggcgaaaata
    11641 atgaaagaaa ggaagttctt tgttttgtcc ttgtattttc ctaaatgagc tacttcatct
    11701 gctaggaggc cacagataat tccaggaagg aaggaaccag caccgtgttt agttcccaag
    11761 aaaaagaggg caatgacaag gccgatagtg gtaatggctc caaagcgcgg aacttttgcg
    11821 actaggatca tatagacgct accgccgaca agggcagtaa aggcaggcgc ataaaacatg
    11881 tttccagttt ggtcaaagag attgcccaaa aggacaccaa tccccatgca gaggaagtaa
    11941 agaactgcaa aaagcagtgt agttaagata gatttcttca tgaattgtct cctgataatt
    12001 ttttcacaat tctcattgta ccacggtttg gtgggattgt aaatggatac tagaagtttt
    12061 tgaaaacgct tgaaatatga tataatggtt tcatagttat ttttagggga atatcatggg
    12121 tagattttta gactttgtct ttaatcgttt ctttttaggg atgattgcga cagccttctt
    12181 ttggctatta actttagcag gagggattat ccttggtcta gcgccggcta gtgccacctt
    12241 gatgagctta tatgcagaac atggttatag ctttcgggaa tacagtttga aggaggcttg
    12301 gtctctttac aagcaaaatt ttgtctcaag caacctgatt ttctatagct ttttaggtgt
    12361 gggtctagtt ttgacctatg gtttgtatct cttggtgcaa ttgcctcatc agaccattgt
    12421 tcatttgatt gcgacccttt tgaatgtcct agtagttgcc ctgatctttt tggcttatac
    12481 agtatcttta aaattacaag tttattttgc cttgtcctat cgaaatagtc tcaaattatc
    12541 cttgattggc atctttatga gtctagcagc tgtggccaag attctccttg ggactgtgct
    12601 acttgtagca attggttact atatgcctgc cctgctattt tttgtaggaa ttgggatgtg
    12661 gcatttcttt atcagtgata tgttggaacc tgtctatgaa atcatccatg aaaaattggc
    12721 gacaaaatag aatgaagcag ttttggctac atacgcttct aagaacctat agttcagtga
    12781 tgatcattat cattgcgagt tttgcaatct tactctctta cgctgactgg gattcacgtg
    12841 aaaaggaagc ccagagagta gcccagcgtg taactgctag aacagtgagt gaaattgaat
    12901 attaccatag agagtcaacc cagatagctc aggctttagt tgaaaaccaa gctcgtattg
    12961 agggaatcta taaatacttt agtcttagca tgccagacta tttttactgg caattagagc
    13021 ggaaagcttc gccttatata tcagtctctc tgtatgaaaa tgttgatgac ctctatgttc
    13081 gaaatgattt tgtaactgga gtggccattg cttttcaaga ttacaaggaa gtctatgttt
    13141 ctactaaaga caaacgtagt ggagaaaaaa tcagggctga ggatttcaaa ccagcaggaa
    13201 atagttttgc cattccggtg tcagatccag tgtcagatca agatttagga gtgatttaca
    13261 tctccttgaa tcctgctgtt ttataccatg ccattgataa tactagaggt catactccga
    13321 tggcagtaac agtgacctca ccttttgata cggagatttt tcatattggt gagacagttg
    13381 atagggagag tgaaaattgg ctagttggct taacttctca tggatatcag gttcaggtgg
    13441 cagttcctaa aaactttgtt ttacaaggaa cagtgactag ctctgctttg attgtgggtt
    13501 tgagccttct ctttattgtc attctttatc tgactttgag gcagactttt gctaattacc
    13561 aaaagcaggt agtggattta gtggaatcca ttcaagtcat tgctcaaggc gaagaggggc
    13621 gtcggattga catttccgaa aaagatcagg aattactcct aatcgcggag acgaccaatg
    13681 atatgttgga tcgattggaa aagaatatcc atgatattta ccagttagag cttagtcaaa
    13741 aagatgccaa tatgcgagcc ttgcaggcgc aaatcaatcc tcattttatg tataatacgc
    13801 tggagttctt gcgcatgtat gcagttatgc agagtcaaga tgagttggca gatatcattt
    13861 atgaattcag tagtctcttg cgtaacaata tttccgacga aagagagacc ctcctcaaac
    13921 aggaattaga attttgccgt aaatacagct atctctgcat ggttcgctat cccaagtcca
    13981 ttgcctatgg tttcaagata gatccagagt tagagaatat gaagattccc aagtttacct
    14041 tgcaaccgct ggtagaaaac tatttcgcgc atggtgttga ccacaggcag acagataatg
    14101 tgattagcat caaggctctt aaacaggatg gttttgtgga aattttggtg gtcgataatg
    14161 gtagaggaat gtcggctgaa aagttggcaa atatccgaga aaaattaagt cagagatatt
    14221 ttgaacacca agccagctac agtgatcaaa ggcagtctat cgggattgtc aatgtacacg
    14281 agcgttttgt gctctatttt ggagaccgct atgccattac tatagagtct gcagagcaag
    14341 ccggtgttca gtatcgtatt acaattcaag atgagtagaa agggagaaaa tgtataaagt
    14401 attattagta gatgatgagt acatggtgac agaaggtctg aagcgtttga ttccctttga
    14461 taagtgggat atggaggtcg tcgcaacagt cagtcatgcc gatgaagctc tagaatatgt
    14521 tcaggaaaat cctgtcgatg tcatcatttc cgatgtcaat atgccagaca aaacagggct
    14581 tgatatgatt cgggagatga aagagatctt accagatgct gcctatatcc tgctctcagg
    14641 ttatcaggag tttgattatg taaaaagagc aatgaacctt agtgtggtgg actatttggt
    14701 caaacctgtt gataaggtag agctgggaaa tctgctggag aagattgcag gtcagctcgg
    14761 cgagagaggg aagaaaagtc agactcttag tcaagaatta gacgaggctg aatttgttag
    14821 ttatttaggg gataaggaga attggtggat aggtctatcc aaggaaaaac aaggttcctt
    14881 caccattccc tactatgtct tgggccagga ctggcagatt ttcatttctg accaacccct
    14941 agatggttta gtcgttacac cttttgaagc tccttatcaa gaacactttg aacgctggaa
    15001 gctgaatgct gagaaaaccc tcttttacgg ttctgtaaat ttgcagcagt ctgagagtct
    15061 ctttgcctat tacgaaccga tttatagggt tatcattcag ggaaatctca atcaaatcgt
    15121 agaagagtta aatctcttgg agaaggtagt tcttgaaaat acgccgcgtg ttccgattac
    15181 taaacagctt tttattcagt ttgtcatgga tgttttccat ttatttgaac atctcaaagc
    15241 tgatgacctg acagacatcg tcaaaaccat tcatgctatt caatccttcg atgaattggt
    15301 tccttatatc aaggaaactc tgaccagctt tttcggtcaa taccgtatga atgaaaatgt
    15361 ggtcagtgtg ctggaagtca ttggtcgtga ttaccaaaaa gagctttccc tcaaggatat
    15421 cagtaaggat ctctttatca atcctgtcta tctagggcag ttgattaagc gtgaaaccga
    15481 ttcgactttt gcagagttac taaacaaaca acgtattaag gctgcccaac aacttttgct
    15541 ttcaactagt gacagcatcg aagatatttg ttatgctgtt ggttacagta accttggata
    15601 tttctataaa gttttccgaa aattgtgcgg aaaatcgcca aaagcctacc gaaaacaggt
    15661 agaaactata ctataagatt tgtattcctt tacaaaatgt gctataatat aaatattatt
    15721 atcaggaggt tctatcatga aaaagaaacc aatttatcta tgggtcttgc taatcttgtc
    15781 tgcccttatt tcagttccgt ctctgtttgg aattgtgagt cccttgccta gtaaagaagc
    15841 ccttcgtact gctcagaaac aagttgcagg ggtcaatgct cagcaattag aagaccagct
    15901 taattatacc tatagagtag cagaagcatc tcattctatt tttaatgttg ctttgattgt
    15961 gctatctact attttagtgg tcgtagcgat tgtcttcctt gttcgtaaaa atttgcaata
    16021 tgcaaactat acttacgttg gctatgtttt gttagctatt attggttcga tttatggcta
    16081 tgttggttta caagacgctg tgcagttggt tcaagatgag agcatgcgtt tgacagtgag
    16141 tattggttca aaagctgtta gcattttcta tatcgtcatc aatgttctct tcctagccct
    16201 tgtcttctat aagatgtggc gacaacagaa agccttggca gaagaagagg aaacagaaga
    16261 gcttacctaa gtattgacaa aaaagaacta tcaagataca atcttggtag ttgttttttg
    16321 attatagata aaatcatgga ggtacatatg aagacaattt ctttagttta tattagtttg
    16381 agtggcaaca ctgaaagttt tgtgacgcgc ttgaaagact atctcttgtc ccagtacaaa
    16441 gggattgagg ttcaaaagat tcatatcaag gatttggtca aggaaggcaa aaatttctat
    16501 gaaatggacc atccctatgt cgcttttttg ccgacctatc tcgaaggtgg gaatggcgtg
    16561 gataacggag atgttgagat tttgacgaca ccggtgggag attttattgc ctatggtaac
    16621 aatgctagta agtgttttgg tgtggttggg tcaggaaatc gtaactttaa taaccaatac
    16681 tgcctaacag ccaagcaata cagtcaacgc tttggcttcc ctgtattggc tgactttgaa
    16741 atgcgaggca tgctggaaga tatcaaacat gtcgcagcta ttatcgcaga tttgtatgag
    16801 ttggaaaagg agaattaata ctcaatgaaa atcaaagagc aaactaggaa gctagtcgca
    16861 ggttgctcaa agcacagctt tgaggttgca gatagagctg acgtggtttg aagagattct
    16921 cgaatagtat aaagttctta taagatgtgg ttgaagttgt tcaactgttt tttgagtata
    16981 aacagtcttt aagaacgtaa aaaagcataa gttcaggtct tcaaaacctt gttcttatgc
    17041 tttttatcat agaaatattt gctgaatttt ctcttgaaat gaaaccttat cttcatctcg
    17101 cgcttgtccc ttaccctgct tttccgattg cgagtgcgta gataaagaag atggcgaagc
    17161 caaagaggaa aatcaatccc gcaatggcaa ggtgtttgag ccaagaagga agatttttgt
    17221 tttcacgtgt taccaaggcg taattcaaaa gagcaaagaa aggtgttgtc aggaaagagc
    17281 caatcatggc aaagcggagc atggttgaaa cctgaccagc gaagaacttg ataatgacga
    17341 taccgatgat agcagtgatg gtcatccaga tgttcaaaga tttacgattg tcctcttttt
    17401 gactgattag cagtcggaga gattcctgat taacgcgaga atagccatcg ataacagtta
    17461 taactgttcc aaagatacag aggaaggcaa taaaggtaat caagtaacgg gaccattcgc
    17521 caagaacaga ggcatacatg cccacgaatt gagagatgta tttggctgaa gcagcttcaa
    17581 ccgcctgccc tgtaggatac tgaatcagtg ctcccagtgc cacaaagaag acggctagga
    17641 tagctgttcc aatataacca gtgttaaagt caaacagagc gtcttctgtg ttaaagttga
    17701 cggtctttct cttttcagct gaccaaagtg aattgatggc tgaaatttca ataggagccg
    17761 gcatccatcc taggagggag acgatgaagg gcagagctgc catttgccaa ggtgtcttct
    17821 cgacaaaatc agaactgtat tctggatgct tgaccgccgc aatgataact gcaagaacag
    17881 tcgcaatggt taaggcagac ataatccatt tgaccatgcc gtctaaaagt ttgtagcctc
    17941 caaagagtag catagcccaa atgattgcaa cgagaatgag ggaccactga gtaatgctaa
    18001 gtccaatcat tgggaaggca ctggcgatga tagctgagca cagaatggca acaccagccg
    18061 tgttgaccat agccgaaaag acattgagaa taaagaaaat ccagagatag agttttcctt
    18121 tttcggcata accttcaacc aaagtctttc cagtatcagc tgtgtattca gcaccaaaac
    18181 ggaaaaatgg atatttaaag acattggcta agatgaccaa gagaagtaga gaccaaccgt
    18241 aagaaccgcc agcttgagtt gaggatacaa tgtgggaacc tccaacagcg gcagttgcca
    18301 ttaggattcc aggtcccatt gcttttagct tgcttgccca ggttgattga tttaaggaaa
    18361 tagcttgcga catgataaat actccttttt gaattttcag aataatctgt atatgcaatc
    18421 tatattctac aaaaaatttt ggaaaaatgc aagaatattt tgaaaaaaga tagaaaattt
    18481 acaaagaaaa tctgaaataa ctgttatgat atagcagatt gaaactagaa tagtacactt
    18541 ttgcttctaa aacattgtta gaaatcgatt tgactgtcct gattgattta tcctgttctt
    18601 atttcatttc actatagtaa ggtgcagcag gataaagcaa aaccgagaag tttctttctc
    18661 ggttttgctt attatgaggt tcctattttc tatgctccaa gagttgattg atgtgatcta
    18721 cttttttagc ctctctttta tagagaatag cccagatgat gagatagaca atcgcaaact
    18781 cgataatgag ctggaggtag aaaatccagt ggaaggggaa ccaaccagca agagttgcta
    18841 gtgggacaaa gccagccagc ataaggaaga aatgagtcag agtggcacga agcatgctcc
    18901 agtcacggct gaataagcgg ttgccaaagt tgaagagcat accgatggct gcccagataa
    18961 gtgtgcagta gagcaagacc agggcaccgt gaacctgatg ctgatccatc acttggccga
    19021 tgagagagta gggatttagt ggtgcgtagg tatttggtgc ataaatgagt gaaaagagga
    19081 tggagaggat gaggccgata agaacaccgg cagctgcatc gtgaaatact tgttttttca
    19141 tagttctaat ttctccttga tggtttttag ataacggcgt gaagagtagg tgaagctttc
    19201 gtttttcaag aaaatttcta ccagaccgtt tggcgtgagc ttgaggtgag agatggaatc
    19261 gatattgatg atttctgatt gggaaatttg gataaaattg cttggcaaga gtttaagaac
    19321 ctgatagagt cgcaaatcaa tgctgtaggt ctgactcgcg gtttctgcta gaaccttccg
    19381 attctcgata tagaagcgct gaatcttgcc aatctcaact agatagacct gatcatcgat
    19441 ttttcctttg attttttctc tttggtccag attttctgcg aactcgatga ctttctggac
    19501 tttttcggtt tcttgaggtg cttggacaat cagcttttcc tcctcgtaag tctcactaat
    19561 ctgtagttct actttcataa atttctctcc ttgtttttca tacaaaatta atctcacttc
    19621 ttgtacacct ttattaatac tcttcaaaaa tctcttcaaa ccacgtcagc gtcgtcttgc
    19681 cgtaggatag ttgttgactt tgtcagtttt atctacaacc tcaaaacagt gttttgagct
    19741 gtctgcgtct agctttctag tttgctcttt gatttttatt gagtatacca ctattttact
    19801 ccctctggca agggactttg tctatgtgga gggattgggc tcctatgtgg tggagttttt
    19861 ctgttctttc tgaaatatgg tataatagca ctaattaatt tctaggaaaa tagatacaga
    19921 aaggggctga aagatgtctc atattattga attgccagag atgctggcaa accaaatcgc
    19981 agctggggag gtcattgaac gtcctgccag tgtggttaaa gagttggtag aaaatgccat
    20041 tgacgcgggc tctagtcaga ttatcattga gattgaggaa gctggtctca agaaggttca
    20101 aatcacggat aacggtcatg gaattgccca cgatgaggtg gagttggccc tgcgtcgcca
    20161 tgcgaccagt aagataaaaa atcaagcaga tctctttcgg attcggacgc ttggttttcg
    20221 tggtgaagcc ttgccttcta ttgcgtctgt tagtgtcttg actctgttaa cggcggtgga
    20281 tggtgctagt catggaacca agttagtcgc gcgtgggggt gaagttgagg aagtcatccc
    20341 agcgactagt cctgtgggaa ccaaggtttg tgtggaggat ctctttttca acacgcctgc
    20401 ccgtctcaag tatatgaaga gccagcaagc ggagttgtct catatcattg atattgtcaa
    20461 ccgtctgggc ttggcccatc ctgagatttc ttttagcttg attagtgatg gcaaggaaat
    20521 gacgcggaca gcagggactg gtcaattgcg ccaagcaatc gcagggattt acggtttggt
    20581 cagtgccaag aagatgattg aaattgagaa ctctgaccta gatttcgaaa tttcaggttt
    20641 tgtgtcttta cctgagttga ctcgggctaa ccgcaattat atcagcctct tcatcaatgg
    20701 ccgttatatc aagaacttcc tgctcaatcg tgctattttg gatggtttcg gaagcaagct
    20761 tatggttgga cgttttccac tggctgtcat tcacatccat atcgaccctt atctagcgga
    20821 tgtcaatgtg catccaacta agcaagaggt gcggatttcc aaggaaaaag aactgatgac
    20881 cctggtttca gaagctattg caaatagtct caaggaacaa accttgattc cagatgcctt
    20941 ggaaaatctt gccaaatcga ccgtgcgcaa tcgtgagaag gtggagcaaa ctattctccc
    21001 actcaaagaa aatacgctct actatgagaa aactgagccg tcaagaccta gtcaaactga
    21061 agtagctgat tatcaggtag aattgactga tgaagggcag gatttgaccc tgtttgccaa
    21121 ggaaaccttg gaccgattga ccaagccagc aaaactgcat tttgcagaga gaaagcctgc
    21181 taactacgac cagctagacc atccagagtt agatcttgct agcatcgata aggcttatga
    21241 caaactggag cgagaagaag catccagctt cccagagttg gagtttttcg gacaaatgca
    21301 cgggacttat ctctttgccc aagggcgaga tggactttac atcatagatc agcacgctgc
    21361 tcaggaacgg gtcaagtacg aggagtaccg tgaaagcatt ggcaatgttg accagagtca
    21421 gcagcaactc ctagtgccct atatctttga atttcctgcg gatgatgccc tgcgtctcaa
    21481 ggaaagaatg cctctcttag aggaagtggg cgtctttcta gcagagtacg gagaaaatca
    21541 atttattcta cgtgaacatc ctatttggat ggcagaagaa gagattgaat caggcatcta
    21601 tgagatgtgc gacatgctcc ttttgaccaa ggaagtttct atcaagaaat accgagcaga
    21661 gctggctatc atgatgtctt gcaagcgatc tatcaaggcc aatcatcgta ttgatgatca
    21721 ttcagctaga caactcctct atcagctttc tcaatgtgac aatccctata actgtcctca
    21781 cggacgtcct gttttggtgc attttaccaa gtcggatatg gaaaagatgt tccgacgtat
    21841 tcaggaaaat cacaccagtc tccgtgagtt ggggaaatat taaaagtata aaaaagtctg
    21901 ggaaaaattt tcaaaatcag aaaaacgcat aaaatcaggt gttcaaaaac cttgatttta
    21961 tgcgttttat catggaaata gttacttcat gttttcctaa ttcttttcga aactcttttt
    22021 aaaccacgtc agttttatca gtaatctcaa aacagtgttt tgagctaatt ttgccagttt
    22081 tgtctgtaac atcgaagttg tgttttacca ctctgcgact ggtttcctag tttgctctat
    22141 gattttcaca gagtattaaa ttgcgatttt gccaagtttc tttattcgtc taaaagtaga
    22201 gtctgttcta tgcgtctaat gtacgaatta ggttgaccat ttcaatagct ccttgtgcac
    22261 actcagaacc cttatttcct gctttggtac cagctcgttc tatggcttgt tcaattgtat
    22321 ctgtcgttag cacaccaaac ataacaggaa tttcgctatt taaactgatt tgggcgattc
    22381 ccttagatac ctcgctacat acataatcat aatgacttgt attccctcta atgacagctc
    22441 ccaagcagat aattgcatca tattttttac tttttgccat ttttgatgca atcagtggta
    22501 tttcaaaagc tcctggaacc caggctacct ctatatcttt ctcgtttaca ttctctcttt
    22561 tgagattatc tagtgctcca gataataatt ttgaagttat aaattcatta aatctcgcta
    22621 caacaatacc tattttaata ttgtttgcta ctaaattacc ttcataagtg ttcatttatt
    22681 tttcctccat atttaaaatg tgacccattc gatttttctt tgtttctaaa taaaaactat
    22741 cgtaaggatt ggcttctatt tcgattgata ttctactgga aatggtaatt ccatattttt
    22801 ctaactgttc aaccttgtca ggattatttg tcagtaaatg aagtgactga agtcccagat
    22861 ctttaagcat ttgtgctcca atatgatatt ctcttaaatc accttcaaag cctaatgcaa
    22921 gattggcatc aagcgtatcc atgccttgat cttgtaaatg ataggctttt aatttattga
    22981 taagtccaat tcctcgtccc tcctgtcgca agtaaagtaa gacacccgaa ccattctcaa
    23041 caattatttt catagcttta tcgaattgct gtccacaatc gcaacgtaaa gagcctaaaa
    23101 catctcctgt taaacattcg gagtggaccc gacataatac attggcttca tcctctatgt
    23161 ttcccataat aagagcaaga tgatgttccc catttagttt atctatatag ctaattgctt
    23221 tgaaattacc gtatctagta ggcatattga cagttgaaac tcgttctacc agctgatcat
    23281 atgcttttct atattcttgt aattctttga tggtaattag tggaatgttg tgtttcttcg
    23341 agaactgaat taaatcatct attctcatca ttttgccatc atgattcatt atttcacaac
    23401 ataggccaca ctcttttagt ccagctaatt ttaataaatc aacagttgct tctgtgtgtc
    23461 catttctttc tagaacacca cctttttttg caattaaagg aaacatgtgt cctggcctgc
    23521 gaaaatcaga gggtgttata tcttcagcta cacacatacg tgcggtcagt cctctctcct
    23581 cggcagaaat acctgtggtc gtttctttat aatcaattga aactgtaaaa gcagtcttat
    23641 gattatctgt attgttttca accataggtg aaagcattaa ttgattagct aaactttcgc
    23701 tcataggcat acaaattaat cctttggcat aagtagccat aaaattaaca ttttctgttg
    23761 tagctgcttg tgcagaacaa attaagtctc cttcattttc tctatccttg tcgtctataa
    23821 caagaacaag tcgtcccttc tgcaatgctt ctaatgcttc ttgtattttt cgatattcca
    23881 ttgactgatt atcctttctg ctaaaatcca ttttgatata atagttcctt cgatatttct
    23941 gattttggag agttatccat cagtttttgc acatatttac ctaagatatc attttcaaga
    24001 tttactgtac tcccgacttg tttactctta agaatggttt gtttcaaggt atgagggata
    24061 acagatactg aaaagtttac tttggagact ttagcgacag tcagactaat gccgtcaatt
    24121 gtaatagatc ctttttcaac tattaaatct aaaatttctt tttgtgtgtt gatttgatac
    24181 catacagcat tatcatcttt ttttattgac gagatttttc ctgtaccatc aatgtgtcct
    24241 gtaacgacgt gacccccaag tcgaccgttg acagataagg ctctttctag attcacctca
    24301 cttccatgtt ttaatagagt aagagctgtt cgactccatg tttcattcat tacatcaact
    24361 gtaaaggatt gatgattgaa atgagtaact gtaagacaga taccatttac tgctatacta
    24421 tcgcctaaat ggatatccgt taatattttt gaggctttaa ttgatagttt acaattacga
    24481 gagtctttct gtattctttc aacttttccg atttcttcaa ttattcctgt gaacatggat
    24541 aaatcacttc actttctatg agatagtcat ttcctatttg agaaaaagca taaggtttca
    24601 atctaatagc gtcatttggc aaagaaatgc cttcacctcc gacaggaaac ttggcactgc
    24661 ctccaaaaat ttttggtgca atatatattt tcagctcatc aacaatttgt tgttccaaag
    24721 cactccaatt cattagactg cccccttcta gaactaggct atcaatctgc atgtttccta
    24781 gatgttgcat taaactcgat aagtctatat gattgccttt tttctttatg gaaagtattt
    24841 cacagccatg attttgatat agcttcattt tatttttgtc ttcagaggaa gtggcaatgt
    24901 aagttttaat atcatttgct gtttttacga ttttagaggt aagaggagtt cgtaaatgtg
    24961 tatcgcatat gatacggata ggatttttcc cttcctccaa tctacatgtc agcaaaggat
    25021 cgtcttgaat aacagtattg actcccacca taattgcact aacatggtgt cgtaactgat
    25081 gcacatgctt tcttgcctct tcttcagtaa tccatttgga ttgatttgtt ttagtggcta
    25141 tttttccatc aattgtcatt gcatatttca taaaaacata gggtacatgc tgggtaatat
    25201 actttctaaa actttttatt aagttaagac actcattttc taaaattcca acagtaactt
    25261 gaagattatt ttcctcaagt atctttactc cttttccaga tacaatagga ttacagtcta
    25321 ggcttccaat gactactctt gtaataccac tatcgattat agcatctata caaggaggtg
    25381 ttttcccgaa gtgacaacag ggttcaagtg ttacataaag cgtcgctccg acaggggatt
    25441 ctctacagtt tttaagagca tttctctcag catgtgagcc accaaaaaac tcatgataac
    25501 cttgtccgat gatgtgatta tcttttacaa taactgcgcc gaccatagga ttgggattga
    25561 cgtaaccagc ccctttttgt gccagtttta ttgctaattt catatatttt gaatcgctca
    25621 tctcactacc tccaaaaaaa tataccttga ataggagact actcaaggca tacaaaagaa
    25681 aacttatgcg attaacaaaa atgctctgaa atgacaagta atcatttcag agcacgcaaa
    25741 aagcacaaat atacttttat cttctttcat ccagactata ctgtcggctt tggaatttca
    25801 ccaaatcatg cctttcggct cgtgggctat accaccggta gggaattgca ccctgccctg
    25861 aagatagtta ttcaattaca gatgattata gtacttaatt ttgaatatgt caacagataa
    25921 ataccgattg tttttgatat actgtatttg tgataatcga ttctcgctcc tcggataaag
    25981 aaaatatgat atactagata aacgaaataa gagagaagga acactatgta cgcatattta
    26041 aaaggaatca ttaccaaaat tactgccaaa tacattgttc ttgaaaccaa tggtattggt
    26101 tatatcctgc atgtggccaa tccttatgcc tattcaggtc aggttaatca ggaggatcag
    26161 atttatgtgc atcaggttgt gcgtgaggac gcccatttgc tttatggatt tcgctcagag
    26221 gatgagaaaa agctctttct tagtctgatt tcggtctctg ggattggtcc tgtatcagct
    26281 cttgctatta tcgctgctga tgacaatgct ggcttggttc aagccattga aaccaagaac
    26341 atcacctact tgaccaagtt ccctaaaatt ggcaagaaaa cagcccagca gatggtgctg
    26401 gacttggaag gcaaggtagt agttgcagga gatgaccttc ctgccaagat cgcagtgcaa
    26461 gcaagtgctg aaaaccaaga attggaagaa gctatggaag ccatgttggc tctgggctac
    26521 aaggcaacag agctcaagaa aatcaagaaa ttctttgaag gaacgacaga tacagctgag
    26581 aactatatca agtcggccct taaaatgttg gtcaaatagg agcagagaat gacaaaacgt
    26641 tgttcgtggg tcaagatgac caacccactc tacatcgcct atcatgatga ggagtggggc
    26701 cagcccctcc atgatgacca agcgttgttt gagttgttgt gtatggaaac ctatcaggca
    26761 ggcctgtctt gggaaacggt actcaacaaa cgccaagctt tccgagaagc ctttcatagc
    26821 tatcaaattc actcagtcgc agagatgact gacactgaat tggaagccat gctggagaat
    26881 ccagctatca ttcgaaatag agccaagatt tttgctacac gcgctaacgc ccaagccttt
    26941 ctacagttac aggcagagta cggctctttt gatgcctatc tttggtcttt tgttgagggg
    27001 aaaactgtcg ttaacgatgt tcctgattat cgccaagccc cagctaaaac acccttatct
    27061 gagaaattag ccaaagatct caaaaaacga gacttcaagt tcacaggccc agtcgccgta
    27121 ttgtcttttc tacaggctgc agggctagtt gatgaccacg agaatgattg tgagtggaaa
    27181 ggtcttaaat gatgtctaac aaaaataagg gaattctgat ttttgcgatt ctctatacag
    27241 tcctctttgt gtttgatggc gttaaattgc tggcttcttt aatgccatct gccattgcaa
    27301 attatcttgt ttatgtagtt ttagctttat atggctcctt cttgttcaag gatagattga
    27361 tccaacaatg gaaggagatt agaaagacta aaagaaaatt cttctttgga gtcttaacag
    27421 gatggctctt tctcattctg atgactgttg tctttgaatt tgtatcagag atgttgaagc
    27481 agtttgtggg actagatgga caaggtctaa atcagtctaa tattcaaagt acctttcaag
    27541 aacaaccact actgatagct gtttttgctt gtgtcattgg acctctggta gaagaattat
    27601 ttttccgtca ggtcttattg cattacttgc aggaacggtt gtcaggttta ctaagcatta
    27661 ttctggtagg acttgttttt gctctgactc atatgcacag tttggctcta tcagagtgga
    27721 ttggtgcagt tggttactta ggtggaggcc ttgccttttc tattatttat gtgaaagaaa
    27781 aagagaatat ctactatccc ctacttgttc acatgttaag caacagcctc tccttaatca
    27841 ttttagctat cagtatagta aaatgaaatg agaacaggac aaatcgattt ctaacaatgt
    27901 tttagaagta gaggtgtact attctagttt caatatactg taatatgtga tgaaaatgcc
    27961 agtaatgata ccgagaaaaa agctgagaaa cttttcccag ctttatttgt tatagtcaaa
    28021 gagaatgact tgttcctgtg catctacatg agcatggacc ccaaagggta caattgctct
    28081 tggagttgcg tggccgacat tcagattata gacaatcggg atattgctgt caatgatatc
    28141 caatagtgcc tctttatagt cgtcatggaa agtttcatcc ataggttttc cgaccaagag
    28201 tccattgatg accgcgaata tgccagtgtc ctttaaagtt agcaacatct ttttgaagtc
    28261 ttctggctta ggcttttctt cgcttgtttc gagcaagagg attttccctt cccagtctga
    28321 caagtcaggg aaaagtttgt atttttggca gagttccgtg ctatctgcgt atcgagagtt
    28381 gtcaaagata tcgtagaggg attcgaggca accaccgagg attttcccct cgaactgagc
    28441 acttccttgc aacaagtcaa aacctgtatt tgtatgactg acacgaggtg ttcccagggc
    28501 cgtgggacta aaatcagttc gttcctcata ccaaacgtca ctagggcgga tttctgaaat
    28561 tcttcccgtc tcaatcaatt ctttaaagta gtgaaggcta taggctagca tttctttgtc
    28621 taattcacaa atgtctgcta aaaaggattg accataaaaa gtcttgattc ctaatttatg
    28681 caacatgagg tggttcatgg ttgtatccga gaagccaaga aaaatttttt gtttgataac
    28741 cttttggagt tggtcatttt caaaaagata aggtagcaag cgataggtat cgtctccacc
    28801 gatggcacat aggatcatgt cgatgctatc atcagaaaag gcatgaatca aatcctctgc
    28861 acgagcttca ggatggtcct tgataaagtc taatcctttt aacgaatggg gcaaaaagat
    28921 gggattgagt cccagatcct tgagacgttg gatacccaag tccacttcgt gtttgacaaa
    28981 atcctctccg ataatgccac tagataaact aacaatacca atagtagaaa ccatatctca
    29041 tcctcctaga aatagattga gcctatttta tcacaaaata taagagaaag ctatgtggga
    29101 tttcagaaga atacttttaa tactcttcga aaatctcttc aaaccacgtc agttttatct
    29161 gcaacttcaa agctgtgctt tgagcaacct gcagctagct tcctagtttg ctctttgatt
    29221 ttcattgagt acaactcaaa aaagtaagtg aaaaagcaac cgcacctgca gttgctttta
    29281 tcgttttctt attcttgata gcgtgttggt cctgcacttg cactacggat attcaagcgt
    29341 ttcttgagat agaagcgaag ggctaggagg gctgctccaa taatagctag tggcaatgga
    29401 tccagtactg ggttaaggct agctggtagg aagcttgttg caaagaagac aagcaaccaa
    29461 aggaacatag aagctaggat aactagtaca gatttccaga aaggtggacg ttgactgcga
    29521 tccatatctg gtccatagta ttggtaaaca aagtagtaca tcaagtagaa ggcaaatcca
    29581 ccaaccagtc caactaatag aagagtaatc aatccatagc cgaaagcttg atctgccgca
    29641 aagaaggttg tgagggcgct gacaagggca aagaggctag tgatgaaaag agctgagtcc
    29701 ataatcatca gttttggatc atcattttct tttggatgct ctttttcgta ctgctctttg
    29761 acagtgaagc tatgagccca atgagttggt gcgccgtata gggaacgggc agttgtacct
    29821 ttagattgct cctcaaggat ttggggaatg acttcctcaa aaatagtctg gatttcagcg
    29881 tctgttttcc catctttgat gaattgttgg gtagcaatgt ggacaaactc ttggtttttc
    29941 ttagttaatt tttgtagatc aatttgagac ataggaactc ctcttagaac cattttttat
    30001 ggatgagata gagagtgagc gagacactca tagcaaaggc gataaagacg attaaccaga
    30061 aggcatttgg ctctccgttt aggggaattt cattatcctt aaagttcatc ccgtaggcag
    30121 aaaagaccat ggttgggatg gacatgacga tggtcacaag ggccaaggtt ttcatgatgt
    30181 tgttctggtt gttagaaatg atagaggcaa aggtctctgt catagaatgc aagacgtttc
    30241 cataaatatc tgccatctcg atggcctgtt gggtttcaat cagggtgtct tcaagcaggt
    30301 cttcgtcctc aaggtatttc ttgatattgc tggttgaact ggtcaatttc ttaatcacgc
    30361 gctcatttgt tttgagggag gccttgaaat agacgatagt tttttccaat tccatgagct
    30421 caatcaattc ttcattacga gttgattgat gcagttgact ttcgatttgt tcactcttgc
    30481 ggtcgattga acgaagggct gttaggtaaa gctctgcatt gcgataaaga atttgaaaga
    30541 taaaacgtga acgcatgaag gtatagaaat tacgcaatcg acggttgata aagacatcaa
    30601 ggacaggtag tggttccaaa cacgtagtga taatggtttc ctcagtgatg ataataccaa
    30661 gcgggatggt tacgtagtag gtgcggttat ttctttcctc cgtgaccggc acgtctacga
    30721 taatcagggt atactcgtct tcaatggtaa tacgagacat ttcttccgca tcgagcggtg
    30781 ctcgaaggtc ggcaatatca atatcgaagg tgttggcgat ttcgagtgat tcattttgag
    30841 tcggattgac gagattgatc caagtacccg gttcaagcgt atcgatctct ttaaattcag
    30901 ttgttgtaga gagaaaaact tgtttcatat cccttatcct ttctcatttt tcagattttt
    30961 tcacactgta ctattatact acaaaatcgg cttttttcaa ataaaatctt acaaagacac
    31021 cgttgttatt ggatttttac tttgtcttga aatgttgatt tttaaatttg ctcccctttt
    31081 tgctccccct atagtgcttt tagtgcagtt tcgtagaatg atactgcttt ttttgcgttc
    31141 tcttttgaga ggtgactata tatatccatg gtcattgata aagtggaatg acctaggcgg
    31201 tactggagtt ccttgtatgg tattccagag ttaagcaaga gactagcgtg agtgtgacgg
    31261 aatccgtgaa atccaatgtt aggaacatca gcacgcttaa aatgtgtttg caatcttctt
    31321 ttaagtcttg aactgctagg atactcatga atgaaatcag aaaataccac gcgttcacgt
    31381 tgccctatct tccaggcctc tttagtttgg cgtagtttgt actgcttcag catgctaaca
    31441 gtcgcttgat ctatatctat atcccgataa ctagccttag actttgggct attgatttct
    31501 atatcccgat ttagtgtttt ggtaatatgc acaacggcat tatctaagtc aatatcagac
    31561 caggaaagag ctaaagcttc attgatacgg caaccagtag ccaataggaa cttatagagt
    31621 gttgtctcat agtagtaacg atatctatga gtatctaaat tatcgagata accaagaaat
    31681 tttttagttc ttgattttca aagtgcttta cttttttccg ctttgctttc tgagtgttac
    31741 gaggtaaaac aacatcacgc gcaggattgg acggtatagc ctgcatggtt acgccatact
    31801 gtaagatacg tttgtttaaa gcgtgtatct tgtcataatg tagaaaagcc gctttttccc
    31861 ctctattagt cttgtcagca agttcgttga taattgactg gataagtgga gtagtgagct
    31921 tatcgagctt gtaagcccca aaaataggca atatatgatt atcgattagc tttttaacat
    31981 tgccttgagt gtttggctta accgtattct tataactttc caaccagaga gttgccaatt
    32041 cttgatagtt ttttatggta acagcctttt gtctggtaga tcctgctttt tgaaaagcta
    32101 ttttttcttg attggctttc tgcttaactt ccttttgtgt ccgacctgtt actttggttt
    32161 ttactttctt tcctgttacc tggtcaactc ctagatatac attagcacga taaactttgc
    32221 taccgtcttt ttttataact tcagttattt tcatgatgat aaacctttct aaaatacatc
    32281 agcaggcaag ccattatcaa aaaggtttta tatcatgcta ggagctacga gaaccccctt
    32341 attttcgttt tatttcttcc agtaaagaat acatagcatt aatgtggtta tatttttgaa
    32401 attcaggatc ttggttttgt gtaataaagt atacgtattg tctaccagat ttgaatttat
    32461 cgatagcttg tttttccact aattttttta aatattttaa aattgtattt ttgtggattt
    32521 ttagtttttc ttccaaagcc tctcttgtta cgaaacggtg ttcgattatt aactctaata
    32581 tctttttctc atattcgtta tcaatatcca gattatctat aagggaagta tcccataatg
    32641 taaattcaac tgagtctaat tcagttcgta aattgggata ttttaaatga ctctctttaa
    32701 ctgcttccat tattttgggt ataccagttc ccgctttttc acataaattt aaaaatctaa
    32761 aaatttcttg tattaagtag tttcttggat cagaatgtgc cccactaaaa aagtccttta
    32821 tgtcaattct aagtgttccg ccatttgtga atatatacct gtcgggatat ctaattatca
    32881 ttatcccttt ttcgctttta tagtcgctat gaataaggct attaatgaat gcctcacgaa
    32941 ttgcaattcg taattttgaa attccaattc tattcataga attttcttga atgttagagt
    33001 tgtcatttaa agttagatat aatttttcaa taactaggta aaagaaatta aaaagattat
    33061 cttcccccca tgtaccatca taaatcacac gatctttaaa gcgattgttt tcagaaaact
    33121 cttttagaac atattctacg ttatagtgtg gaataaactc ttttattgaa ttatgtgtac
    33181 caaaaattaa tagtccagca actgttggct ttattttatc gtccttgcga tctcttcgta
    33241 aagcatttat ttttattaaa aattgttcgt tatccaactt tgaaaaaggg tgctccgcat
    33301 ttatattatc aaatttttct ctatatagct ttattgtttc tgtatctaag tctaaaatag
    33361 aaaaatcctg aataagtgtg ctatcaaaac tttccttagc ggaatctctt aacatagagt
    33421 tgatttgctc ttgtgaacac ctaaaatcac cagtcccctg acgaaaatag gtagatgcta
    33481 tgttgtcatt aagatatata ggtttatcct tgtagtctac cttgttaaca gggataatga
    33541 caatctcttt tccttttata tttacgactt caacactttc ttcattaatc acatttctat
    33601 taattttatt agggttatta agtaaactat ataattcgtc cagtacttta tcgggatcat
    33661 taactccaga aatataaaaa tctttattct ttgtattctc tgagacacct agaattaaca
    33721 gaccattatt tgtattagcg aaggaacaaa ttgttttcat accgtcttta gggaaagaat
    33781 ttttagcttc tttgaattca acaccttggt tctcccctga taataacaat tttggtatat
    33841 cgtattttct cattttttct ccaatcaatt tgcacacgca ttcgcacacg cgcgggaaaa
    33901 atagtttatt tttagttagc taacagtgct attaaaggtt tttttgaaag tagattattc
    33961 gcacacgcat tcgcacacgc gcttcaggat tgttgaacat tgtggcgcgt gggttagtct
    34021 ataccccaaa gtaacgcaaa atcatctaga ttttctttat ctttcttagc ttcttgaaga
    34081 gctaaagact taatttcttc aaatagattt tcaaactttt tatataattt gttgtaatat
    34141 tcttggttga attccttatc ttcaaaaact atgtagaatt cactacttgt tttttgaaat
    34201 acaatatcta gccagaatag gatattactt gtctttagcg caagggcatt taaaacttca
    34261 tagttgtctt tgggattgta ttcatttaat gattcagtga tagtagtgag aaactcttca
    34321 ggactgattg ggaaattttt actctttgct agttcaatta tttccttgtc tcttttctct
    34381 ctctctttta ctttctgaaa aattttatct tttgaaacat tttttacgag gtatttttct
    34441 tcgtctaatt gtttatctaa catatataaa aattctttgt aaacatcttt gtcagaaaag
    34501 cgagggtcaa gatcagattt tttcactccc aaataatcag caagtttttg aagattgcca
    34561 gatgttggca ttgatctacc ttttacataa ccagttattg tacttttagg aatttctaaa
    34621 gcattatgca ggtctatctg tctgatacct ttttctttca taacacggtt aagattatta
    34681 gagaaatatt ctctattctt taaatcctga gggctatttt ttgccattgt taaaaactcc
    34741 cttactttaa ttctacaacc tgattataac acaaaaaaga caaagtacga aaaaaataaa
    34801 atttttcaac aacagcgttg ataaagtacg aaaaaaatag taccatgatt ttatcaatct
    34861 tgaaaggagc tataagaata tggcacaatg gacgctaaga gcgtgtcgag taaatgcagg
    34921 ttttactttg cgccaagtgg ctaagaaggt caacaagaat tttcagacta tctcaaagta
    34981 cgaaaaagat agtacgctaa tcccttttga gctacttaaa gagttatcgg aactgtatca
    35041 ggtaaaactg gacgatattt ttttaggaga tagtacgaaa aaaatagaac taaatcaaaa
    35101 ggaaatctaa gaaaggagca aaccaatgga attagtctac atggacggta agaaagagcc
    35161 gtatacactg agcagtattg ttgcggagtg tgcagaagtt aagcacagac atttgaagat
    35221 tttgctgaat aaacatcgag aggacttcga gagtttcgga aaggtgcaat ttaaaatttc
    35281 accttcagaa agtgggcaaa atgtacggga ctatattttg aatgagcaac aagcaacctt
    35341 gctgatcact tacttacgaa atacagaacc cgtaaaagag tttaagaaga acctggtcaa
    35401 agcattcttt gaaatgcgtg aggagctttc taagttccgt atgcagaggg cgctagaaaa
    35461 gccaaaaaga aaaaccttgc atgacagtat agagacatgg gaggcaaaac ccaagcacgc
    35521 gcatagcacc atgaacaacc tgctactaaa agcagtaact gacatgaacg ctaagcagtt
    35581 aagggaagaa cgtgggggct ataacggtat tgatagcttg accagtgacg agctggagca
    35641 ataccaggca tttgaggata tggtaatagc catgatcggc ttgaatatga gttaccaaga
    35701 aatcaaggct atggcattca gaaataaaaa aacacgccaa agaagcgcgt gagagcaaca
    35761 aaaaaggctt agcaataacc acaccgcaga gcctttcaca ctaacactaa aacgaattta
    35821 acaaagcagg caagctatta tcaaagaggt tttagtaaag atttatacct agattatagc
    35881 atatttaggg caatttgacc atacggagag cgccaactct ttaaactggt actttctcat
    35941 gctctcaatt tggcgactca gagcgtgagg ctatgaattg caagaaaaac tgtataagaa
    36001 acaaccatta aaaaccccca cactctcggt cggcaaactt ctgagcgtga ggatatccag
    36061 tatagtaaaa ggcattaaaa gctcttagag caattacaca acatagaaac aaaggtaaaa
    36121 aacatgacag aaacaacata cgagaattta actagacata tagacagaat tagcgcagaa
    36181 atgcgagaaa ttggcgaaaa aaatgggctt agtagacttt cattattggc aaatcagaca
    36241 aaattcatca aagaaaattt acaccgttta ctttggattg aacttcctga attgaatgac
    36301 agccataaaa tcgaggcagt ttctaaaagc actacgggaa tgtttttcca cgctggtatt
    36361 tttgaaatgg acgctatgcg acaagcattc tttaaacgcc aagctatgca cttttttgac
    36421 aacgaagcag agcaacaggc gtatatagaa catgctgaaa aggagtattt agaggctact
    36481 ataaccttaa aagatattct ttttaactct aaaaatggaa ctcagagagt aaataaaagt
    36541 tgtcttatag agaagtttga ggaggcaatg caatgacact aaacctagac aacatgacac
    36601 aagcagagtt tgatgaagta atggctgaaa ttaaggaaaa acgccccaac ctcttccagt
    36661 ttattgctga ttttgtagat cgaaaagtaa gcactgagga ggtagacgaa tacctgaaga
    36721 tgaaacatga aaaacaagtg gaatttatca agaattatca agcgagggca taacatgaat
    36781 gagttagatt tgaccaatac acaatcggta atctttatgg tggtattgat tggcttactg
    36841 ctttacctaa accaccgaga ccgcaaaaaa agcgcccaat ttgagcgaga aaaccaacag
    36901 aggatagaaa cacctagcga ggatttaagc cctgattatg ggcgttatat ccagcttgca
    36961 ggggtaagag tttacggagg aactgaatga gtctatcaga gaatgacaaa cgagtattaa
    37021 gactaatcaa ggtaggggct gagaactcca taacaggggc agaaatcagc cttataacta
    37081 agctggcgga aagaaccgta caagatatta tcagccgtct aatcacgcgt catagtgttc
    37141 ctattgttgg ggttcgccat gggacattta gaggatattt tatcccagct aacaaagagg
    37201 agctactgga cggagcaaag gcattctata accaagtaca ggaagaacag aaacgcctaa
    37261 ctgtcctttt gaatgctgat ttagagagtt acaaagaaac cttgaaggag gtgggcggat
    37321 atgtttagcc taagccgaga aagtgagcaa gacctagcgc atggcattct ggaggtagta
    37381 gaaagatacc tggaagcgcg tgatacagtc aagccacgac tgacaggttt aatatcagcc
    37441 caggaagtca tggacgagtt agatataaaa tacatgacac tccaaaagtg ggaaaaagca
    37501 gggctaagac ggtatcagcc accgctagaa gatactagga aaatctatta taaaatatct
    37561 gacatctgga agtttttggg ggtggaaaat ggcaaggtat agtattcatc cggcagataa
    37621 taaagggcat tatcacaata ttaaatttta caaagagcgc aggccaaccc tagaccagct
    37681 aaaggaacag caaaggctta aaaagctgaa gaaaaaacgc aaaaaggggc gatagtatga
    37741 caatttatga ggctaaaggc tttcagagta atcttgtcta tccatttgat aaaattgagc
    37801 ctttccagta tattgaacga ttcaagccct tagtagttcc tgaaggggca gatattgagg
    37861 aatacaagcg aactcaagcg ccttactgta taagtggcaa agtgacgcca gaaaagcatg
    37921 gcagttacaa gcgaaacaac tccagtctaa tctatcggga tttgattttc cttgattatg
    37981 acgatataca ggggacgtct gagggcttta taaaagccat ttctagcgct ttatttggct
    38041 actcttacat cttatacccg actatcaaac atagcttaga aaagccccgt tttcgccttg
    38101 tagtgaagcc tgacaacgtg atgaatgagg cgacctataa gcaggtagtg aaagagattg
    38161 ctgacaagat tggactcccc tttgatatgg ccagtttaac atggtcacaa ctccaagggc
    38221 taccagtcac aacaggcgac ccagcaagtt atcaaaagat tgtagagcat ggacttgatt
    38281 atccagtacc acagacaacg gctgaaccag tcaaacagaa tgcggcaagc cttccataca
    38341 ctccaaggcc aagcgggcag aaatctatga ccatgaggat cattgacacg cttttcaacg
    38401 gatttggaga cgagggaggg cgcaacgtag cactgacacg atttgtaggc ttactcttta
    38461 ataagtgggt tgattgtgac ctagagacag cctatgaact tacaaagata gccaatagcg
    38521 tgacagttga accattgccg attgaggagc tagaccgcac ttttagcagt atagcacggg
    38581 ctgaatatag aaagagaggt tagaaccata gaactagaag aattagcaaa cctaaaaagt
    38641 gaaatcttgg aggtaatgga gcaagaacac cctcctagaa cgatgaagga gcttgaaaat
    38701 cgtatcttta aagctggaga agaatggcgg gcagaacata ctgaaactaa ggtaaatgag
    38761 aacacagggg acgttaccga aaaggttgcc atgccccaaa ccttcacagt agctaaaata
    38821 ctgagcgaga ttgtcacatt tacttttatc agcaagagca atatacctga ttatagccta
    38881 ctctatatct atgatttaga cgagggtatc tataccgcta gtaatgatct attcaatctt
    38941 ttgtgtaaga cctttgacgt tagaattaaa cccagagagt ggccacagat taagttaatg
    39001 gttagaacat tggcaaagat acgaaaacct ttagaaagtg ctaacctcat tcccgtacag
    39061 aacggcatta tcaacttaga aactaaggaa ctactcccct ttagtcctaa gtatgtaatt
    39121 acaagtaaga taagcacggc ctaccacgcg cctaaacgag tcccaacaga tagagaggga
    39181 aaaacttttg atgattggtt gaactcaatc gcttgtaatg atagtgaact ggtaacactg
    39241 ttttggcaga ttatccttga agctattgac cctaaccata ctcgaaataa gtttgctatc
    39301 ttctacgggg acggtaacaa tggtaaaggg acatttcagc gcttccttat caacctgata
    39361 ggggaaagca atatatcagc cttaaagcct gcacagtttg ctgaaaagca taacttggag
    39421 accttggtag gtaaggtttg taatattggg gatgaagcac ctaacgaata cttaaaaaat
    39481 ccgtctgatt taatgagtat cactagtggc gacactgttc tagtcaatcc aaaaggacgc
    39541 ccagcctttg aagctacttt caagttattc aatatctttt cagggaatta tatccccaat
    39601 ggtggcaaca agacaaaagg ctggtatcgt agaattatga ttgtcccttt taatgctgac
    39661 tttaacgggg agaaggaaaa accttggata aaaaatgagt ttttagcaaa caaggaagtc
    39721 ctagaatatg ccctctacaa agctatcaat caagagccat ttactcactt tatcgaacct
    39781 aaagcagtta aaggactcct agaagaatac caggaagata atgactactt actttcatgg
    39841 gttaagcatg aatacatgga aaaaggttgg catgagctgg acgtagtacc tgtttttatc
    39901 gttacaagat cactaaagca ctatgccgaa gatatgggaa tacccaagcc caatgtttac
    39961 ggggctggta aagaaactat caagcactta caacagttga cacctaatcg gtattctcta
    40021 agaaagaaaa gagtttctcc agaagatttt gaaaaactag aggcatggga cgttgacaag
    40081 ataaaaatgc ggacacctca acactctatc actaaacaag aataagtgtg acgttctttt
    40141 tttgcttaaa cccttgataa tactgatttt cttgaaaaaa gtgtgacgtt gtgtgacgtt
    40201 ctcaaaaaag aaggtcacac cccttgaagc cttgatatat ctaactttag gggaataggt
    40261 gtgacgttgt gacattcttt ccaactctta tatatagaga aaaatacagt atttatatat
    40321 ataggaacga taaaacaaaa gaacgtcaca gggtcacagg ggtggtgaaa cacctagagc
    40381 ctcaagggtt tgaacgtgtg acgttctttg tcacaaaagg tcacagaaaa cgaaaaatat
    40441 tacataattt accttaaaac aaagaaatga caacaacatg aaagttaaac tatttgaata
    40501 tactagacga tgggaaaaag aagactttga gaaagagatc gatgacttca tggcaactgt
    40561 tgaagtgctg gacgttaaat tttctggtac accatctagt gaatccttta attcggtggc
    40621 tatcgtattg gtattataca gataacaaaa tggggtagat agtaccgacc cccttgcaat
    40681 ggtgtaacta ctagtgacac ccttaaaaac agaaagagga aaaacaacat gacattaaaa
    40741 acattttcat ctaaagccaa aacatttact ttcacttacg aatttaaaga cctagataca
    40801 gctctggtag caggtcacgc gttactggga tatatgactg gaacatattg ccagcctgta
    40861 atctcattga cctacaagga taaaggcacg ctagtagctg agtatgtgga agatcacaag
    40921 ctaaacaaga cctttaagcg tatttgtgac agttttaaag actaccacaa acaaccagga
    40981 gaggctgaag catttgaaga acgttacaaa cgggagcgcg tgctccaact caaagagtca
    41041 gaggactttg agagtttact gaataaggtc acagactacg agctggaact attagactat
    41101 gctgaccgcc tgctttctga taagcctatc cctatggact ctatgactgc ttttgctacg
    41161 ttggaaatgc tgggcgatga aagtattagc ctactccaaa agttggacgt agagggcgaa
    41221 tataaaggcc ttgctggtta tacagagcat ttgaagtaga atacagggga gcaatcccct
    41281 ttttgctatc aagtcaatag ttttgggttt ttccatatag ggggaaataa tgaagcagtt
    41341 agcaatagaa gcaatcacta aaccaatgaa gctgagagga atatctaagg gtatagccga
    41401 gttggatggt caacgtttag agattgattt ggatagttta atgattgatt ttggtggaga
    41461 gtcatttgaa ttagacagaa tagcaggaac taagggaggt aatcgatatt tttttctttg
    41521 ccctgattgt ggtagacggt gcaggttgct ttataaacgg tatttgtatt ttagttgcgg
    41581 tacttgtcta gatatccaca agcacaccct gaaccgcagt aaaacggatt gccaatacta
    41641 ctgggagctt gcactaaaag aagctagaaa ggtagaacca gggtggagtc ctagacgtgg
    41701 cggatatatg tttgatagtt ttcctgaaag accaaaatac atgaaacaga aacgatatta
    41761 caagcattat caaaagttta ttaactacac cagaaaaggg gatagctttt ggctgaatgg
    41821 tttgagttct ctaaggtaat ttgtagtagt gtgcaattta caaaacaaac aaatactaca
    41881 tattagacgg tttgaatgtt aaaaaagcta gatatatcaa ggatttaatt aagtatagcg
    41941 ttccaaaaaa agggtgcagt aagcgttcca aaaaagggtg aggttgaata tttaaaaaag
    42001 gctaagatta ggctaaggtc acatacttca aaatagcaag gttttagcaa ggtacagggc
    42061 ttttttctag tgatagaacc ccaaggttac cacaaggtat agctactttt ttagaaccat
    42121 agaacggtaa ggttacggta aggtatcgaa gttttccaat ggtaaggttt tggtaaggta
    42181 gcatatataa aaagtacaag gttagtacaa ggttacatac ttaaaaatac taaggtttta
    42241 caaaggtaga gaggtttacc gagggttaga aaaggtgaga ttttgcttag gtagtggcag
    42301 taaatatgcc tgacaaatgg cagggttatg tgtgttgaac tccgagcgaa cgccgagaaa
    42361 gtggctatat cccccctatc atttatcaag tagataagag caataaaaac cctccttaac
    42421 cccctgagaa acgacaagca gataagagaa gtttttagcc ctcttatttc ggatctactc
    42481 cttgcagaat gacaagcaga taaggacgac aataagcctt cttaactgct tacaaaacga
    42541 tagggagtta agacgaattt aaaagcccct tattttcgtt tttctccttg tcaaacggga
    42601 aggaaataag acaggaaata acatcgctta ttttgatttt gctccctgaa aaactgtaag
    42661 gagataagga gacttattag cttccttaat ttgaattttc tccttacaaa atgacaggga
    42721 aataagaact aaaataactc cccttatttt cctaccaaat gataaggaga taagagcagt
    42781 ttaaaagtct gttattttgg atttgttgct tacaaaatga taagcagata agcaaagaaa
    42841 taacttgcct taattgcttg cagaatgaca aggaaataag agagataaaa acatccctta
    42901 attgcttatc aaatggtatg gagaatggac ttgaacctag agcgaagcta gagaaaatga
    42961 aaaaaagcca gcacagggct gactccttta tgaattattc cataaaacta ttatatcaca
    43021 aaggaggccg aggcatgaca ccagagcaag taaaagaaaa actagagggc gttaagtgga
    43081 taaacaagga gatcaaaggc ttatatttgg aattggaaac cctggaaggt ggcattatca
    43141 aaaaaccaac actaagccat agcagggtgc agacaagtag agagaataag acagagaaca
    43201 atcttataag tgttctgaag ctaaaagagg acactttaca gagaattgag cgacttactg
    43261 aagagagaat gaaaatatct gagctaatcg ataaactggc caatccgctt gagcgttctg
    43321 ttctaagact tttttacttg aatgatcttg tagtttcgga ggtggctgaa gaaatagata
    43381 gatcaaatac tacagtatac attataaggc aaaaagctat agaacactta acaggtattg
    43441 taaacgggga ttgatttaac cttaccacgg aattaggaga gtatggggga gtcctaagcc
    43501 acatattcgc ccgtatttcg ctttgtttcg tactggacaa ctaaaacacc atggataaac
    43561 tacaaaccct cagaaacgaa tctgggggct tttgtgaggt cataatctta taaaccacgc
    43621 gcttcatggt ataatatatc tatcagcaac cagcaataaa aaagcacgtt tgaccgtgct
    43681 agtttcttgc ctgctgaact cgtcaaatct tagccctttt gtggggcttt tttgctcccc
    43741 tttttgcgta ctttggggga gcaagtagta aaaagtaatg ttagtaattt ttattaaaaa
    43801 gcgcgtgata taagggttag gaagccctaa ggaaacataa aataagcgat tgttgattat
    43861 actacaaaat cggccttttg ggtaatagaa tctcactttt tttggtataa tggtaagcaa
    43921 taatggacta gaaagaacaa agatgcaaga taaaattgtc attcatgggg cgcgtgccca
    43981 taatttaaaa aatattgatg tggagattcc gcgagacaag ttggttgtcg tgactggctt
    44041 gtcaggttca gggaagtcca gtctggcttt tgatactctc tatgcggagg gacaacgtcg
    44101 ctatgtagag agtttgtctg cctacgctcg tcagttcttg ggaaatatgg aaaaaccaga
    44161 tgtagatgcc attgatggtc tcagcccagc tatttccatc gaccagaaaa cgactagtaa
    44221 aaatcctcgc tcgacggtgg gaacgacgac tgaaatcaat gactatctgc gtctcctcta
    44281 cgcacgtgtg gggacgcctt actgtatcaa cggacatgga gctatcaatg cttcttctgt
    44341 ggagcaaatc gttgataagg ttttggagtt acctgaacgc cagcgcttgc agatcttggc
    44401 tcctgtcatc cgcaagaaaa aaggccaaca taagagtgtt atcgagaagg ttcagaaaga
    44461 cgggtatgtt cgtgttcgtg tggatgggga agtctatgat gtgaccgaag tgccagagtt
    44521 gtctaagagc aagcaacaca atatcgatgt cgtggttgac cgtattgtta tcaaggaggg
    44581 cattcgtagc cgtctctttg attccattga agctgccctt cgtatcgcag aaggttatgt
    44641 gattatcgac accatggacg actctgagtt gttgttctct gagcattatg cctgtccagt
    44701 ttgtggattt actgtcccag agttagagcc tcgtctcttc tctttcaatg ctccctttgg
    44761 ctcttgtagt gagtgtgacg gcttggggat taagctggag gtggatactg atttggtagt
    44821 gccagatgcc agcaaaacct tacatgaggg agcgctggca ccttggaatc ctatctcatc
    44881 caactactat ccaaacatgt tagagcaggc catgaaagtc tttggagtgg ctatggataa
    44941 gccttttgag gacctgtcag aagaagataa gaacttgatt ctctacggct cagatggtaa
    45001 ggaattccat ttccattatg aaaatgaatt tggtggtgtg cgcgatatcg acattccgtt
    45061 tgagggagtt atcaataata tcaaacgtcg ttaccatgaa accaatagcg attacactcg
    45121 cactcagatg cgtctctaca tgaatgagct gacctgcgga acctgtcaag gctatcgtct
    45181 caatgaccag gccttgtctg tccgtgtggg cggccagcaa gggccacata ttggagaaat
    45241 ctcagacctg tctatcgctg accacttgga cttggtgagc cagttaactt tgtctgaaaa
    45301 tgaagccatc attgctcgtc ccattctcaa ggaaatcaag gatcgtttga ccttccttaa
    45361 taatgtgggt cttaactatc taaccctgtc acgttcagca ggaacccttt caggtgggga
    45421 aagtcagcgc attcgtttgg caacccagat tggttccaac ctatcaggtg tcctctatat
    45481 cctagacgag ccgtcaatcg gtcttcacca gagggacaat gaccgcctga ttgccagtct
    45541 gaaaaagatg cgtgacttgg gcaatactct tatcgtggtg gaacacgacg aagataccat
    45601 gcgtgaagct gattatctga ttgacgttgg tcctggtgcc ggtgtttttg gtggtgagat
    45661 tgttgcagca ggtacaccta agcaagtggc tcgcaacagc aagtctatca caggtcagta
    45721 cttgtcaggc aaacgtgtca tcccagtacc agaagagcgc cgtgtcggaa atggtcgttt
    45781 tattgaagtg acaggagcgc gtgagaacaa cttgcaaaat gtcacggctc gctttccact
    45841 aggaaaattt atcgcagtga caggtgtgtc gggttcaggg aaatcgactc taatcaacag
    45901 cattctcaaa aaagccattg cccagaagct caaccgtaat tcagacaaac ctggtaagtt
    45961 taagactatt acagggattg agcatgtcga ccgtttgatt gatattgacc agagccctat
    46021 cggacggacg ccgaggtcta acccagctac ctatacagga gtttttgacg atatacgtga
    46081 cctttttgct cagacaaatg aagccaagat tcgaggctac aagaaggggc gcttcagttt
    46141 caacgtcaag ggaggtcgct gtgaagcttg ctcaggtgac gggattatca agattgagat
    46201 gcacttcttg ccggatgttt atgtggcttg tgaagtttgc cacggaaccc gctataacag
    46261 tgaaacccta gaagttcact acaaggaaaa gaatatttcg caggtcttgg atatgacggt
    46321 caacgatgcg gtagaatttt tccaacacat tccgaaaatt caacgcaaac tccagaccat
    46381 caaggatgta ggtctaggct atgtgacctt gggacagcca gctaccaccc tttctggggg
    46441 agaagcccaa cgtatgaagt tagctagcga actccacaaa cgctcgacag gaaaatcttt
    46501 ctacattctg gatgagccga cgacagggct tcatacagag gacattgctc gcctgctcaa
    46561 ggttttagct cgctttgtag acgacggcaa tacagtcctc gtcatcgagc acaatctgga
    46621 tgttatcaag acggcagacc atatcattga cttgggacct gagggcggtg tcggtggtgg
    46681 aaccatcatc gtaacaggaa ctccagaaga agtagctgcc aacgaagcca gctatacagg
    46741 acactatttg aaaggaaagt tacatcatga ataaacgcgt acaagcattt ctagctaaaa
    46801 tgcaagaaaa agaactagat ggtatcatca tcaacaatct taaaaacgtc tattatttga
    46861 ctggtttttg gggctcaaac ggaacagtct ttatcagccg tgaccgtcag gtcttagtga
    46921 cagactctcg ctatatcatc gcagctaagc aagaaaccag tggttttgag attgtggctg
    46981 atcgtgatga attggctgtc attgcaggaa ttgttaagga catgaacttg actcgtatcg
    47041 gttttgaaga tgagatttca gtgtcttatt accaccgtat gcaggcagct tttgcaggtt
    47101 tgaacttgct tccacaaact cagtttgtgg aaggtcttcg tatgattaag gatgaggcag
    47161 agattgcagc gattcgcaag gcttgttcta tctcagacca agctttccgc gatgcgcttg
    47221 actttatcaa accaggaaaa actgaaattg agattgccaa cttccttgat ttccgcatgc
    47281 gtgagttggg agcatctggc ttatcttttg atacgatcct agctagcggt atcaattctt
    47341 ctaaacccca tgcccatcca atgcacaaac cagtggagtt gggagaagcc attaccatgg
    47401 acttcggctg tctctatgac cactatgtca gtgatatgac ccggactatc tatctagggc
    47461 atgttagcga tgagcaggca gagatttaca atacggttct aaaagctaac caagccttga
    47521 ttgaccaagc taaggcaggc ttaggtttcc gtgactttga caaaatccct cgtgatatta
    47581 tcattgaggc aggttatggt gactacttta ctcacggcat tggccacggt attggtctgg
    47641 atatccatga ggaaccctac tttagtcaga cttctacaga aactattaag acaggtatgg
    47701 ccttgaccga tgaaccaggt atctatatcg aaggcaaata tggcgttcgt atcgaggatg
    47761 atatcctgat tacagagaca ggttgtgaat tattgaccct agctccaaaa gagttgatag
    47821 tcatttagtt gtttgtcaag aaaaaagtac gaaaatgacg aaaaaagtca aaaaaaatta
    47881 aaaataggtc gcaagtcgga tgttttttat ggtataatag actaaactga tagtaacatg
    47941 tagcgaaagg ggtaggtaca tgattaaaat ttatacagtc tcaagttgta ctagttgtaa
    48001 aaaagcaaaa acctggctca atgcccacca gttaagttat aaagaacaaa accttggtaa
    48061 agaaggaatt acgagagaag aattactgga tattctaacc aaaacagata acggaatagc
    48121 cagcatcgtt tcgtctaaaa atcgctatgc caaagccctt ggagtggata ttgaagattt
    48181 gagtgtcaat gaagttctca atctgattat ggaaacaccg agaattttaa agagcccaat
    48241 ccttgtagat gaaaaacgcc tgcaagttgg ctacaaggaa gacgatattc gtgccttcct
    48301 accacgctct gtccgtaatg tagaaaatgc agaagcacgt ttgcgtgcag ctctataaac
    48361 atcaaggctg ggagcacttc ccagtcttat tctattttaa tttcaaaaag aaagaagaaa
    48421 gaaatgaaaa aaatagttct tgttagtcta gctttccttt ttgtcctggt tggttgcgga
    48481 cagaaaaaag aaactggacc agctacaaaa acagaaaaag atacgcttca gtcggcattg
    48541 ccagttattg aaaatgctga gaagaataca gttgtaacta agactttggt cttgcccaag
    48601 tcagatgatg gtagccagca gacacaaaca attacttaca aagacaagac ttttttgagt
    48661 ctagctatcc aacaaaaacg tccagtctct gatgagttga agacttatat tgaccaacat
    48721 ggagtggagg aaactcaaaa agctcttctt gaagcggagg agaaggataa gtctatcatt
    48781 gaagctcgta aattggcagg tttcaaactt gaaacaaaac tattgagcgc aacggaactt
    48841 caaacaacga ctagttttga ttttcaagtt ctggatgtca agaaggcttc ccagttggaa
    48901 catctgaaga atattggttt ggaaaatctt ttgaaaaatg aaccaagcaa atatatttca
    48961 gatagattgg caaatggcgc gacagaacaa tagaaaatcc aaataaatag actgcctgaa
    49021 ttgtagaagg taaggaatta tgctataatg gtactattct aaggaaagag ggtgttagaa
    49081 tgggatttac tgaagaaaca gtacgtttta aattggacga ttccaataaa aaagaaatta
    49141 gcgaaacttt gacagatgtt tatgcttcgt tgaacgataa gggttacaac ccaattaacc
    49201 aaatcgtagg ttacgtattg agtggagacc ctgcctacgt tcctcgttat aataatgcac
    49261 gaaatcaaat ccgtaagtat gagcgtgatg aaatcgttga ggaattggtt cgctactacc
    49321 tcaaaggaca aggagtcgat ctataaccta tgagaattat gggattggac gtcggttcaa
    49381 aaacggtagg ggtggcgatt agcgatccgc ttggttttac agctcaaggg cttgaaatca
    49441 tccagataaa tgaagaacaa ggccaatttg gttttgaccg cgttaaggaa ttggttgata
    49501 cttacaaggt ggaacgattt gtagtgggct tgcctaaaaa catgaacaat acaagtggac
    49561 cgcgcgtaga agctagtcaa gcctacggag caaagctaga agagtttttt ggtttaccag
    49621 tagactatca ggatgaacgc ttgacaacag tggctgctga gcgcatgttg attgaacaag
    49681 cagatatcag tcgcaataag cgcaagaaag tcattgataa gttagcagct cagctgattt
    49741 tacaaaatta tttagataga aaattttaat ataaaggaga ggctatgtca cacgatcata
    49801 accacgacca cgaagaacgt gaactaatca cactagtaga tgagcaagga aatgaaacct
    49861 tgtttgaaat ccttttgaca attgatggaa aagaagaatt tggtaaaaac tatgttcttc
    49921 tagtaccagt taacgcagaa gaagacgaag acggacaagt tgaaatccaa gcttactcat
    49981 tcattgaaaa tgaagatgga acagaaggcg aattgcaacc aatcccagaa gactcagaag
    50041 acgaatggaa catgattgaa gaagtcttca acagctttat ggaggagtga tacagtctgg
    50101 gagactgtat cagcccaact ccagaaatgg ggaagagttg gaacgtccag tgaacatttt
    50161 tactccaact cttagaaatt gagaagagtt ggaacatcta gtggatgttt ttagcccata
    50221 ttcacattca tagtagctag ttattagcta accaggtaag aggtcgggac gaaaatcctg
    50281 gccttgtttt tattagtaac catactttaa tgcgataatt gattggactt ttgtcaagga
    50341 gatgtgtatg tttgaagtag aagaatggct ccatagtcgg attggtttga attttcgatc
    50401 aggtttgggc cgaatgcagc aagcggtgga tttgttagga aatcctgagc agtcttaccc
    50461 tattatccac gtaacaggga ctaatgggaa aggatctacc attgctttta tgagggaatt
    50521 atttatgggg catggcaaaa aagttgcgac ctttacctcc cctcatatcg tctctatcaa
    50581 tgaccgaatc tgcattaatg ggcaacctat agcagacgca gactttatcc gtttgactga
    50641 tcaggtcaag gagatggaga aaacgcttct gcaaactcct gcccagttgt ccttttttga
    50701 attgctgacc ttggttgctt ttctttattt tagggagcaa gaggtggatt tggttttatt
    50761 agaagtggga attggtggct tacttgacac gaccaatgtg gtaactggag agcttgctgt
    50821 catcacctcc attgggcttg accatcaaga aaccttgggt gatagtctag aagcaattgc
    50881 agagcagaaa gctggtattt tcaaggctgg taaaaaggca gtgattgcga aattgcctcc
    50941 agaagctaga cttgtctgtc agaaaaaagc cgaatcttta gctgttgacc tttatcaggc
    51001 aggtcaagat ttttcagtgc tgaatggtga tttttcaagc tctttactaa atctttcaca
    51061 gctgaacata ggcttagaag gagcctatca gcaggagaat gcggccttgg cgttgcaaac
    51121 ttttcttctt tttatgggag aaagaaagga agctattgat gaacaggctg taagaaaggc
    51181 cttggaacag acccattggg ctggtcgctt ggagcgtatt cgcccacaga tttacttgga
    51241 tggtgctcat aacctccctg ccttgactcg cttggttgag tttatcaaag aaaaagagca
    51301 ggaaggctat cgacctcaaa tcctctttgg atccttgaaa cgtaaggatt atcaagggat
    51361 gttgggttat ctgactgaaa atttacctca agtggaactc aaaatgaccg gctttgacta
    51421 tcaagggtct ttggacgaga cagatgtaac aggttaccat gtaattccct cttaccgaga
    51481 atttatcagc agtttcgaag aaagggcaga cgctcaagac ttgctgttcg ttacagggtc
    51541 tctctatttt atctcagaag tacggggcta cctgctggac cgtgagcaga taaattgacc
    51601 cccttttttg aacttgttat actaggggaa ttgctggtta gagaaaattt ctctaaattg
    51661 gtagcagaaa ggaaattcat catgaaatta aaaagattca cactttctct tgcttctcta
    51721 gcaagtttta gtctcttagt agcttgttca caaagagctc aacaggttca acagcctgtt
    51781 gctcagcagg tccaacagcc tgctcaacag aataccaata ctgcaaatgc aggaggtaac
    51841 caaaatcaag cggctccagt acaaaaccaa cctgttgctc aaccgaccga tattgatggg
    51901 acttatactg gtcaggatga cggagaccgt atcactttag tggtaactgg aacgactggt
    51961 acatggactg agctcgaatc tgacggggat cagaaagtca aacaggttac atttgattca
    52021 gcaaatcaac gcatgattat tggcgatgat gtcaaaattt acactgtaaa cggtaatcaa
    52081 atcgtcgtag atgatatgga tagagaccca tcggaccaaa tcgttttaac taaataagac
    52141 tatgcaagta gaaagggctg gatttttcag cctttttact tttacctaga aaataatcat
    52201 aaatacttgc cttctaccga atacctgcgt tatactagta tcaattactt gtttttagca
    52261 ttcaaactat caaggagggg atatgaaata taggaaattt caattattga tgtccaagta
    52321 tggctttagt ctttcgatta tgctacttga actttgtctt gtttttggtc tctttcttta
    52381 tttaggacgc atggctccca ttttatggat tactgtcctc attctactga gtatcatcac
    52441 aatcatttcg atagtcaacc gtaatacgac tcctgagaat aaggtaacct ggttgttagt
    52501 agcctttgtg ccagtatttg gtcccttgct ctatctgatg tttggtgaaa ggcgattgtc
    52561 caaaaaagaa atcaaacaac tgaagaagct aggctctatg catttccaag aagcaaatag
    52621 ccagctacta aaagagaaat taaaagaaag tgacaaggca gcttatggag tcatcaagtc
    52681 cttattgagt atggatacca atgctgacat ctatgatcaa actgcctcta cattttttcc
    52741 taacggagaa gctatgtgga aaaagatggt agaagatctt aaaaaggctg agaaatttat
    52801 tttcttggaa tattacatta tagaagaagg tttgatgtgg aatcgcatac tagatatact
    52861 agagcaaaag gtagctcagg gtgtagaggt taagatgctc tatgatgata tcggctgtat
    52921 ggctacttta acaggagatt atgcacatcg acttcgtcag ctgggcatcg aggcccataa
    52981 attcaataaa gttattcctc gtttgacagt ggcttataat aacagagatc atagaaaaat
    53041 attgattgtt gatggtcaga tagcctatac tggtggggtc aatctggcag atgagtacat
    53101 taaccacgtc gagagatttg gttattggaa ggatagtgga attcgcttag acggactagc
    53161 agtaaaagct ctgacacgct tatttttgac cacttggtac attaatcgag gagaaattag
    53221 tgattttgat caatatcatt tagaaaatca ttctatcccg agtgacggtt taaccattcc
    53281 atacggaagt ggacccaagc caatttttcg agcgcaggta gggaaaaaag tttatcagag
    53341 tttaatcaat caagcaacag aatcggtcta tattacgaca ccttatttga ttatagatta
    53401 tgatttaaca gagacaatca aaaatgcagc tatgagaggg gtcgatgttc gaattatcac
    53461 cccttacata ccagataaga agttcattca gttagtcacg agaggagctt atcccgacct
    53521 tctttctgct ggtgttcgga tttatgagta tagtccaggt tttattcata gtaagcagat
    53581 gttggtagac gaagattttg cggtggtggg gacaatcaat ctcgactacc ggagcttggt
    53641 acaccattat gaaaatgcag tcttactcta taaaactcct tctataaggg aaatcgcccg
    53701 agattttcga aatatatttg cagattctca ggaagtctat cctcattcta tcaaaacgag
    53761 ctggtatcaa aagcttgtaa aagaaatcgc ccaactattc gcccctatct tataagaaat
    53821 ctagaactta ggatacaaac cagacctatt tttcttgtct tttacgaata gaaagaaaga
    53881 ggaggggaat tcatgctaac taaggaagaa gtgaatgata tgattgagtt caaacagaca
    53941 catttacacc gctttcggga aattgaaacc tttgtgaaac tatgcaaaaa atcactcaaa
    54001 cagccatcgc aagctgacaa tcctaggact ttttgatata ctaagacaga taaattgaac
    54061 aggagaaacg atatgagtgt gtatggtaga gtagaagaag ttcataagga gaatcgtgaa
    54121 cctctagaat accaaattga acaagaatcg catcatcgtg aatcaagtcg tcttcctttg
    54181 gtgaaaattt tactatggag tacgcttgta acggggataa ctctaggagt accgctatta
    54241 ctcgacttaa tgagtgcaca agaagtgcag gatttttatg caggttgggc gcttcatcag
    54301 acagggaaga tttacagcga ctattatgga agtcaaggtt tgctttatta tttgctgact
    54361 tacgtgagtc agggcggatt tttctttgcc atctttgagt ggttagcctt ggtagcaggc
    54421 ggatttttcc tttttagatc agcggacacc ttgacaaatc aaggagacca agctggacaa
    54481 ctggtgacta ttttttacat gctagttaca ggtcttgctt ttggtggagg ctatgcgact
    54541 cttttagcgc ttcctttctt attcgcagcc tttagtttag ttgcggctta cctaagcaat
    54601 ccaagccatg ataagggatt tgtacggatt gggctagctt tggcaggcgg atttttcttt
    54661 gctcccttat catcgctcct gtttattgct gtagtgagtt taggcttgtt ggtctttaac
    54721 cttgggcata gacgctttgc gcatgggttt tatcagtttc ttgcagtggc tttaggtttt
    54781 tcacttgtct tttatccaac tgcctactat agtgctgcaa caggaagttt tggggatgcg
    54841 attagtggta ttcgttatcc tattgacagt attcgctttg attttacttc taaaatttta
    54901 gagaatatgt ttttttatgg cttgttgtcc cttggtttgg gatttgtggt ttgtatcttt
    54961 ttaggtctct ttcaatccaa accctttaaa ctatacgtca tttcggttcc tgcaagtctt
    55021 gtggtaattt taggtttgat tttacttttc ttttcacaag agcctctgca cgcttcttat
    55081 ttgatggtcg tcttccctgt tttcctactt ttattggtaa ccaatattaa gagtcaacag
    55141 agggggcgta gtgctagaag aagccgaaga gaaacgccag ttagcctatg gagtcgtttc
    55201 ttcaaaggaa atctatatct gctagttttt gggtttgtct atcttttgtc tgttcctttt
    55261 ttgatgaagt ttgtccttta tccagtacct tatcaagaac gtaatcgtct tgctgatttg
    55321 gtaaaagagg agacaaatac ggaagatgct atctatgcat gggatgatac tgcgactctt
    55381 tatcgtaaga gtgagcgctt gtcgccatcg gcgattttgt ccccgttgca ctatacagca
    55441 actgaggaaa atcgtaataa gttacttaat gacttgaaag aaaaacaacc taaggtgatt
    55501 gtggtaaatg acaaggtgga agtctggtct gaagtggaaa cactcttaaa agaaaattac
    55561 caacaagtaa agactgatta ctcagagttt aaagtctata aaattaaata accaaatcaa
    55621 tatcttgtgt atttttaaaa attttaagat ttttaacaca agatattgat ttttcttttt
    55681 agagtggtat aatacttttt agaaagaaca ttttagaaaa gagcatgcat atgattgcac
    55741 tagaagaaaa aattacaatt ttgccaactc tcttcgtcga gaaacgagat gggagacgtg
    55801 ttgtatttga tgtggacaag attgacaagg ctctccacaa ggcagctgac aaggttatgg
    55861 atgtgacacc cctggttgaa aaacgcctca atgacctgac tgagagaatt attacagaaa
    55921 ttcatagtcg ctttccacag ggaattaaga tttacgaaat tcaaaatatc gtagaacatg
    55981 aactccttga agccaaagaa tatgcgctgg ctgaggagta tattacttat cggacacaga
    56041 gggattttga gcgctcaaaa gcgacggata tcaactttag tattcataaa cttctcaaca
    56101 aagaccagac agttgtcaat gaaaatgcta ataaagacag tgatgtcttt aacactcagc
    56161 gtgatttgac agcagggatt gttgggaaat caatcggact gcaaatgctt cctaagcacg
    56221 tagccaatgc ccaccaaaag ggggatatcc actatcacga tttggactac agtccctata
    56281 cccctatgac caactgctgt ttgattgatt ttaagggtat gttggaaaat ggttttaaga
    56341 ttggaaatgc agaggtagag agtcccaagt ctatccagac tgcgacagca cagatttctc
    56401 aaatcattgc caacgttgct tctagccagt acggtggctg ttcagctgac cgtatcgatg
    56461 aaattttggc gccttatgca gagaagaact atcaaaaaca tctcaaagat gcagaagagt
    56521 gggtattgcc tgaaaaacgg gaagattacg cttggaagaa aacgcaaaag gacatctacg
    56581 atgccatgca atctcttgag tatgaaatca atactctctt cacttcaaat ggacaaacac
    56641 cttttacttc gctaggtttt ggtctgggaa ccagtcgttt tgaacgagaa attcaaaaag
    56701 ctattttaaa cattcgcatc aagggtcttg gttcagaaca ccgtacggct atctttccta
    56761 aacttatttt cactctgaaa agaggcctta atttagaaga aggaactccc aactacgaca
    56821 tcaagcagtt ggctcttgag tgtgcaacca aacggatgta tccagatgtt ttatcttacg
    56881 ataagattgt tgacttgaca ggatccttca aggtgcctat gggttgccgt tctttcctcc
    56941 aaggatggaa ggatgaaaat ggtgtagaag tcaattcagg tcgcatgaat ctgggtgttg
    57001 tgacggttaa tctgcctcgt attgctcttg agtctgaagg tgatatgaat aagttctggg
    57061 aaatcttcaa cgagcgaatg aatatcgcag aagatgctct tgtttaccgt gtcgaacgca
    57121 ctaaagaggc gacaccagcg aatgctccta tcctttatca gtacggtgct tttggccatc
    57181 gtctaggtaa agaagaaagt gttgaccagc tctttaagaa tcgtcgtgcg accgtttcgc
    57241 tgggctatat cggcttgtat gaagtagcga cagttttctt tggtaacagc tgggaaagta
    57301 atccagatgc taaggaattc acgctagaca tcattcacga tatgaaacgc cgtgtagaag
    57361 agtggtcaga ccaatatggc taccatttct ctatctactc aacaccatcc gaaagtctga
    57421 cagaccgttt ctgccgacta gatatagaca agtttggctc tattcctgat atcacagaca
    57481 aggaatacta caccaactct ttccactacg atgttcgtaa aaatccaaca ccgtttgaaa
    57541 aattggactt tgagaaagtc tatccagaag caggtgcgtc aggtggtttc atccattatt
    57601 gtgagtatcc agtccttcag caaaatccaa aggccttgga agctgtctgg gattatgctt
    57661 atgaccgtgt aggctatcta ggcaccaata ctccgattga ccgttgctac aagtgtgact
    57721 ttgaagggga ttttgaacca actgagagag ggtttgcttg tccaaactgt ggcaatagcg
    57781 accctaaaac agtagatgtg gtgaagcgaa cttgtggcta cctaggtaat cctcaagcaa
    57841 gaccgatggt caacgggcgt cacaaggaaa tcgctgcgcg tgtcaaacat atgaatggtt
    57901 caacgattaa aatagctggg catcaagtaa caaattagaa agaaatgaaa tgggaaaata
    57961 tcaactagac gataaggggc gcgcacaagt gacccgttat cacgagaaac actctaaagg
    58021 tggagctggt aaaaaagaac gcttgcttag cttcagagaa caatttttaa acaagaacaa
    58081 gaaaaaataa aagtgagagc cagctctcgc ttttctcata gtgggaggta aggatggaat
    58141 tacgcagacc aagattagcg gataagaaag ctgttttaga tatgatgaca gagtttgaaa
    58201 agagccaatc agcccatgat ggaggatttt gggatacaga gaattttgtg tatgaagagt
    58261 ggttggaaag caatcaggaa caggaaatgg ggattaatct gcctgaagga tgggttcctg
    58321 caattcagtt agtggctttt tctgagaaag gtcaagcagt tggatttctt aatctccggt
    58381 tgcgcctcag taactttcta ctagaagaag gtgggcacat tggctactcc atccgtccat
    58441 ctgaaagagg caagggttat gcaaaagaga ctctccgtca gggcttgcaa gttgctaagg
    58501 aaaagaacat caagaaagct ctggtgacct gtagcgtgaa taatcctgct agcagagcag
    58561 tcattctagc aaatggtgga atatttgagg atgctcacaa tggagtcgag cgttattgga
    58621 tagaggtagc gaatgaataa tccaaaacca caagaatgga aaagcgagga acttagtcaa
    58681 ggtcgtatca ttgactacaa ggcctttaac tttgttgatg gcgaaggcgt gcgtaactct
    58741 ctctatgtat caggctgtat gtttcactgc gagggatgtt ataatgttgc gacttggtct
    58801 tttaatgctg gcattctcta tacagcagaa ttagaagagc agattatggc agaccttgcc
    58861 caaccctatg ttcaaggctt gactttgctg ggaggggagc cttttcttaa tactggcatt
    58921 ctcttgcctc tagttaaacg catccgaaag gaattgccag acaaggacat ttggtcctgg
    58981 accggctaca cttgggaaga aatgatgttg gaaactccag ataaactgga actcttatca
    59041 ttgattgaca ttcttgtcga tggacgatac gatcgaacta agagaaatct catgctccag
    59101 tttcgaggtt cgtccaacca acgaattatc gatgtgcaaa aatcgctcaa aagtgggcaa
    59161 gtagtgattt gggacaagct caatgacgga aaagaaagct atgaacaggt gaagagagaa
    59221 tgaagaaaaa agacttagta gaccaactag tctcagagat cgagacgggg aaagtcagga
    59281 cactgggaat atacggtcat ggagcttcag gtaaatcaac ctttgcacag gaattgtacc
    59341 aagctttaga ttctactaca gtaaatttgc tagagacaga tccttatatc acctcaggac
    59401 gccatctggt agtacccaag gacgcgccga atcaaaaggt gacagccagt ctgccagtgg
    59461 cgcatgaact ggagagtttg cagagagata tccttgcctt gcaggcgggt atggatgtct
    59521 tgacaattga agaaccttgg aaggctagtg aggtcttgtc tggagccaaa ccaattttga
    59581 ttgtcgaagg gatgtctgtt ggctttctac ccaaggaact ctttgaaaaa accatctgtt
    59641 tctacacgga tgaggagacc gaattaaagc gacgccttgc tagagatacg actgtgagaa
    59701 atcgcgatgc atcctttata ttggctagcc atcagatgag acgggagcag tatctgcgat
    59761 actataaaga aactgagtct aaggcggata tcttagtgga ccaatcagaa gataaatttg
    59821 atgtcaagag gacttaactt atgtatagaa gaaatataga agaaaatccc taattttaga
    59881 aagaaaaagt aggaaaacag tttcatccca aaaaaacgaa aaaacctaac aaatcccttg
    59941 caatcgcagg ggatttgtgt tattctatta tggtgctgta aattacagcc ttagttttga
    60001 tgcaagaggt tgcgacacgc tcggttgcat tgccacgcaa caccgcgtcg gttttcttgt
    60061 ggagctagcc tattatctta aatagacgaa aaggagaaaa agatggcaaa caaaaaaatc
    60121 cgtatccgtt tgaaagctta cgaacaccgt acgcttgaca cagcggctgc aaaaatcgta
    60181 gaatcagcta ctcgtacagg tgcacaagtt gcgggtccaa tcccacttcc aactgaacgt
    60241 agcctctaca caatcattcg tgcgactcac aaatacaaag actctcgcga acaatttgaa
    60301 atgcgtacac acaaacgttt gatcgatatc gttaacccaa ctcaaaaaac agttgatgcc
    60361 ttgatgaaat tggatcttcc aagtggtgta aacgtagaaa tcaaacttta atctaaaata
    60421 taaaagagca gaggctggtg tttcaatcta attgaacacg gactaaactc ggtgtgaaaa
    60481 agataaactt cctagtgtct gctagacact gcgtcagttt cctattttca ctttgagttt
    60541 gacgcccttt gtatcttaga cttgagcata aaaaacgctc gttaaaaact ttttgaataa
    60601 aaaatataga aaaggaacta ttttctcatg acaaaaggaa tcttagggaa aaaagtggga
    60661 atgactcaaa tcttcactga agctggcgaa ttgatccctg taacagttat tgaagcaact
    60721 ccaaacgttg ttcttcaagt taaaactgtt gaaacagacg gatacaacgc tatccaagtt
    60781 ggtttcgatg acaaacgcga agtattgagc aacaaacctg ctaaaggaca tgtagcgaaa
    60841 gctaacacgg ctcctaagcg cttcattcgt gaattcaaaa acgttgaagg cttggaagtt
    60901 ggtgctgaaa ttacagttga aacattcgca gctggagacg ttgttgacgt aactggtact
    60961 tctaaaggta aaggtttcca aggtgttatc aaacgccacg gacaatcacg tggaccaatg
    61021 gctcacggtt ctcgttacca ccgtcgtcca ggttctatgg gacctgttgc acctaaccgc
    61081 gtattcaaag gtaaaaacct tgcagggcgt atgggtggcg accgcgtaac aattcaaaac
    61141 cttgaagttg tacaagttgt tccagaaaag aacgttatcc ttatcaaagg taacgtacca
    61201 ggtgctaaga aatctcttat cactatcaaa tcagcagtta aagctggtaa ataataaaga
    61261 aaggggaaat cagtcacaat ggcaaacgta acattatttg accaaactgg taaagaagct
    61321 ggccaagttg ttcttagcga tgcagtattt ggtatcgaac caaatgaatc agttgtgttt
    61381 gatgtaatca tcagccaacg cgcaagcctt cgtcaaggaa cacacgctgt taaaaaccgc
    61441 tctgcagtat caggtggtgg acgcaaacca tggcgtcaaa aaggaactgg acgtgctcgt
    61501 caaggttcta tccgctcacc acaatggcgt ggtggtggtg ttgtcttcgg accaactcca
    61561 cgttcatacg gctacaaact tccacaaaaa gttcgtcgcc tagctcttaa atcagtttac
    61621 tctgaaaaag ttgctgaaaa caaattcgta gctgtagacg ctctttcatt tacagctcca
    61681 aaaactgctg aatttgcaaa agttcttgca gcattgagca tcgattctaa agttcttgtt
    61741 atccttgaag aaggaaatga attcgcagct ctttcagctc gtaaccttcc aaacgtgaaa
    61801 gttgcaactg ctacaactgc aagtgttctt gacatcgcaa atagcgacaa acttcttgtc
    61861 acacaagcag ctatctctaa aatcgaggag gttcttgcat aatgaatttg tatgatgtta
    61921 tcaaaaaacc tgtcatcact gaaagctcaa tggctcaact tgaagcaggg aaatatgtat
    61981 ttgaagttga cactcgtgca cacaaacttt tgatcaagca agctgttgaa gctgctttcg
    62041 aaggtgttaa agttgccaat gttaacacaa tcaacgtaaa accaaaagct aaacgtgttg
    62101 gacgttacac tggttttact aacaaaacta aaaaagctat catcacactt acagctgatt
    62161 ctaaagcaat cgagttgttt gctgctgaag ctgaataatc taaggaggaa atatcgtggg
    62221 aattcgtgtt tataaaccaa caacaaacgg tcgccgtaat atgacttctt tggatttcgc
    62281 tgaaatcaca acaagcactc ctgaaaaatc attgcttgtt gcattgaaga gcaaggctgg
    62341 tcgtaacaac aacggtcgta tcacagttcg tcaccaaggt ggtggacaca aacgtttcta
    62401 ccgtttggtt gacttcaaac gtaataaaga caacgttgaa gcagttgtta aaacaatcga
    62461 gtacgatcca aaccgttctg caaacatcgc tcttgtacac tacactgacg gtgtgaaagc
    62521 atacatcatc gctccaaaag gtcttgaagt aggtcaacgt atcgtttcag gtccagaagc
    62581 agatatcaaa gtcggaaacg ctcttccact tgctaacatc ccagttggta ctttgattca
    62641 caacatcgag ttgaaaccag gtcgtggtgg tgaattggta cgtgctgctg gtgcatctgc
    62701 tcaagtattg ggttctgaag gtaaatatgt tcttgttcgt cttcaatcag gtgaagttcg
    62761 tatgattctt ggaacttgcc gtgctacagt tggtgttgtc ggaaacgaac aacatggact
    62821 tgtaaacctt ggtaaagcag gacgtagccg ttggaaaggt atccgcccaa cagttcgtgg
    62881 ttctgtaatg aaccctaacg atcacccaca cggtggtggt gaaggtaaag caccagttgg
    62941 tcgtaaagca ccatctactc catggggcaa acctgctctt ggtcttaaaa ctcgtaacaa
    63001 gaaagcgaaa tctgacaaac ttatcgttcg tcgtcgcaac gagaaataat attaaactag
    63061 tcgcttaagc aactagtaaa tccgccagct cggtagcgct ccataggagt gcaagccgct
    63121 gtggtacaac atttaaagga gaaaatataa aaatgggacg cagtcttaaa aaaggacctt
    63181 tcgtcgatga gcatttgatg aaaaaagttg aagctcaagc taacgacgaa aagaaaaaag
    63241 ttattaaaac ttggtcacgt cgttcaacga tcttcccaag tttcattggt tacactattg
    63301 cagtttatga cggacgtaaa cacgtacctg tttacatcca agaagacatg gtaggccaca
    63361 aacttggtga atttgcacca actcgtactt acaaaggtca cgctgcagac gacaagaaaa
    63421 cacgtagaaa ataaggagaa cataaatggc agaaattact tcagctaaag caatggctcg
    63481 tacagtacgt gtttcacctc gtaaatcacg tcttgttctt gataacatcc gtggtaaaag
    63541 cgtagccgat gcaatcgcaa tcttgacatt cactccaaac aaagctgctg aaatcatctt
    63601 gaaagttttg aactcagctg tagctaacgc tgaaaacaac tttggtttgg ataaagctaa
    63661 cttggtagta tctgaagcat tcgcaaacga aggaccaact atgaaacgtt tccgtccacg
    63721 tgcgaaaggt tcagcttcac caatcaacaa acgtacagct cacatcactg tagctgttgc
    63781 agaaaaataa ggaggtaaaa tcgtgggtca aaaagtacat ccaattggta tgcgtgtcgg
    63841 catcatccgt gattgggatg ccaaatggta tgctgaaaaa gaatacgcgg attaccttca
    63901 tgaagatctt gcaatccgta aattcgttca aaaagaactt gctgacgcag cagtttcaac
    63961 tattgaaatc gaacgcgcag taaacaaagt taacgtttca cttcacactg ctaaaccagg
    64021 tatggttatc ggtaaaggtg gtgctaacgt tgatgcactc cgtgcaaaac ttaacaaatt
    64081 gactggaaaa caagtacaca tcaacatcat cgaaatcaaa caacctgatt tggatgctca
    64141 ccttgtaggt gaaggaattg ctcgtcaatt ggagcaacgt gttgctttcc gtcgtgcaca
    64201 aaaacaagca atccaacgtg caatgcgtgc tggagctaaa ggaatcaaaa ctcaagtatc
    64261 aggtcgtttg aacggtgcag atatcgcccg tgctgaagga tactctgaag gaactgttcc
    64321 gcttcacaca cttcgtgcag atatcgatta cgcttgggaa gaagcagata ctacatacgg
    64381 taaacttggt gttaaagtat ggatctaccg tggtgaagtt cttccagctc gtaaaaacac
    64441 taaaggaggt aaataaccaa tgttagtacc taaacgtgtt aaacaccgtc gtgagttccg
    64501 tggaaaaatg cgcggtgaag caaaaggtgg aaaagaagta gcattcggtg aatacggtct
    64561 tcaagctaca actagccact ggatcactaa ccgccaaatc gaagctgctc gtatcgccat
    64621 gactcgttac atgaaacgtg gtggtaaagt ttggattaaa atcttcccac acaaatcata
    64681 cactgctaaa gctatcggtg tgcgtatggg atctggtaaa ggggcacctg aaggttgggt
    64741 agcaccagtt aaacgtggta aagtgatgtt cgaaatcgct ggtgtatctg aagagattgc
    64801 acgtgaagcg cttcgacttg ctagccacaa attgccagtt aaatgtaaat tcgtaaaacg
    64861 tgaagcagaa taaggagaag gcatgaaact taatgaagta aaagaatttg ttaaagaact
    64921 tcgtggtctt tctcaagaag aactcgcgaa gcgcgaaaac gaattgaaaa aagaattgtt
    64981 tgaacttcgt ttccaagctg ctactggtca attggaacaa acagctcgct tgaaagaagt
    65041 taaaaaacaa atcgctcgta tcaaaacagt tcaatctgaa gcgaaataat agactaggga
    65101 aggagaaatt tcaatggaac gcaataatcg taaagttctt gttggacgtg ttgtatctga
    65161 caaaatggac aagacaatca cagttgtagt tgaaacaaaa cgtaaccacc cagtctatgg
    65221 taaacgtatt aactactcta aaaaatacaa agctcatgat gaaaacaatg ttgccaaaga
    65281 aggcgatatc gtacgtatca tggaaactcg cccgctttca gctacaaaac gtttccgtct
    65341 tgtagaagtt gttgaagaag cggtcatcat ctaatcaaac ctgaaaggag aaaactgaaa
    65401 tgattcaaac agaaactcgt ttgaaagtcg cagacaacag cggtgctcgc gaaatcttga
    65461 ctatcaaagt tcttggtggt tcaggacgta aatttgcaaa catcggtgat gttatcgtgg
    65521 catctgtaaa acaagctact cctggtggtg cggttaaaaa aggtgacgtt gttaaagcag
    65581 ttatcgttcg tactaaatca ggtgctcgtc gtgctgatgg ttcatacatc aaatttgacg
    65641 aaaacgcagc agttatcatc cgtgaagaca aaactcctcg cggaacacgt atctttggcc
    65701 cagttgcacg tgaattgcgt gaaggtggct tcatgaagat cgtgtcactt gctccagaag
    65761 tactttaatt tttaggaaca aactagtccc ctagcttcaa gctagggtgc ccttatgggc
    65821 gtaagaaaaa tcaaggagaa acctaatgtt tgtaaaaaaa ggcgacaaag ttcgcgtaat
    65881 cgctggtaaa gataagggaa cagaagctgt tgtccttact gcccttccaa aagtaaacaa
    65941 agttatcgtt gaaggtgtta acattgttaa gaaacaccaa cgtccaacta acgagcttcc
    66001 tcaaggtggt atcatcgaga aagaagcagc tatccacgta tcaaacgttc aagttttgga
    66061 caaaaatggt gtagctggtc gtgttggata caaatttgta gacggtaaaa aagttcgcta
    66121 caacaaaaaa tcaggcgaag tgcttgatta atcacgaagg aaaggagaag tataatggca
    66181 aatcgtttaa aagaaaaata tcttaatgaa gtagttcctg ctttgacaga acaattcaac
    66241 tactcatcag tgatggctgt gcctaaagta gataagattg ttttgaacat gggtgttggt
    66301 gaagctgtat caaacgctaa aagccttgaa aaagctgctg aagaattggc acttatctca
    66361 ggtcaaaaac cacttatcac taaagctaaa aaatcaatcg ccggcttccg tcttcgtgaa
    66421 ggtgttgcga tcggtgcaaa agttaccctt cgtggtgaac gtatgtacga attcttggat
    66481 aaattggtat cagtttcact tccgcgtgta cgtgacttcc acggtgttcc aacaaaatca
    66541 tttgatggac gcgggaacta cacacttggt gtgaaagaac aattaatctt cccagaaatt
    66601 aacttcgatg acgttgacaa aactcgtggt cttgacatcg ttatcgtaac aactgctaac
    66661 actgacgaag agtcacgtgc attgcttaca ggccttggaa tgccttttgc aaaataatat
    66721 aggaggtaaa tctaatggct aaaaaatcaa tggtagctag agaggctaaa cgccaaaaaa
    66781 ttgttgaccg ttatgctgaa aaacgtgctg cattaaaggc ggcaggggac tacgaaggtt
    66841 tatctaaatt acctcgcaac gcctcaccga ctcgtttaca taatcgttgt agagttacgg
    66901 ggcgcccaca ttcagtttac cgcaaatttg gtctgagtcg tatcgctttt cgcgaacttg
    66961 cgcataaagg tcaaattcct ggtgtaacaa aagcatcttg gtaatttaag atatcaagag
    67021 cgtcaaaact ccaagtaaaa ataggaaact tgacgaagaa actaaagttt ctaggaaagt
    67081 ttatcttttt cacacagagt ttagcccggg ttcaattggg cttgccaatt tgaacacgag
    67141 ctacagcttt ggcaaaaaag accaatttgc tttggagcat tgcttctgca ttaaattgtc
    67201 tatttttgct cgtgctgtta cgctctttgt atcatgtatt aactagcaag tgcaacttgc
    67261 aaactactag taagaggaga aaaacaaaat ggttatgact gacccaatcg cagacttcct
    67321 aactcgtatt cgtaatgcta accaagctaa acacgaagta cttgaagtac ctgcatcaaa
    67381 catcaaaaaa gggattgctg aaatccttaa acgcgaaggt tttgtaaaaa acgttgaaat
    67441 cattgaagat gacaaacaag gcgtcatccg tgtatttctt aaatacggac caaatggtga
    67501 gaaagttatc actaacttga aacgtgtttc taaaccagga cttcgtgtct acaaaaaacg
    67561 tgaagacctt ccaaaagttc ttaacggact tggaattgcc atcctttcaa cttctgaagg
    67621 tttgcttact gataaagaag cacgccaaaa gaatgttggt ggtgaggtta tcgcttacgt
    67681 ttggtaaaat caagatacaa agctcgtaaa gaacaaagca aaattaggaa gttggagaag
    67741 tttgtttaca aacaagccaa cttatctatt ttgcacagtt cttagagcgt gttcagttca
    67801 gctcttgaac taaataagta tctgaacccc gtgaaaactg gccgttttgg cctgacaatt
    67861 taacaggaga aaataaacat gtcacgtatt ggtaataaag ttatcgtgtt gcctgctggt
    67921 gttgaactcg ctaacaatga caacgttgta actgtaaaag gacctaaagg agaacttact
    67981 cgtgagttct caaaagatat tgaaatccgt gtggaaggta ctgaagtaac tcttcaccgt
    68041 ccaaacgatt caaaagaaat gaaaactatc cacggaacta ctcgtgccct tttgaacaac
    68101 atggttgttg gtgtatcaga aggattcaag aaagaacttg aaatgcgtgg ggttggttac
    68161 cgtgcacagc ttcaaggatc taaacttgtt ttggctgttg gtaaatctca tccagacgaa
    68221 gttgaagctc cagaaggaat tacttttgaa cttccaaacc caacaacaat cgttgttagc
    68281 ggaatttcaa aagaagtagt tggtcaaaca gctgcttacg tacgtagcct tcgttcacca
    68341 gaaccatata aaggtaaagg tatccgttac gttggtgaat tcgttcgccg taaagaaggt
    68401 aaaacaggta aataatgttg agtggttgat catcaaccac caacctattt tccaactttg
    68461 tgcatagcac acgatttaaa actaaagagg tgaaaactgt gatttcaaaa ccagataaaa
    68521 acaaactccg ccaaaaacgc caccgtcgcg ttcgcggaaa actctctgga actgctgatc
    68581 gcccacgttt gaacgtattc cgttctaata caggcatcta cgctcaagtg attgatgacg
    68641 tagcgggtgt aacgctcgca agtgcttcaa ctcttgataa agaagtttca aaaggaacta
    68701 aaactgaaca agccgttgct gtcggtaaac tcgttgcaga acgtgcaaac gctaaaggta
    68761 tttcagaagt ggtgttcgac cgcggtggat atctatatca cggacgtgtg aaagctttgg
    68821 ctgatgcagc tcgtgaaaac ggattgaaat tctaatagga ggacactaga aaatggcatt
    68881 taaagacaat gcagttgaat tagaagaacg cgtagttgct gtcaaccgtg ttacaaaagt
    68941 tgttaaaggt ggacgtcgtc ttcgtttcgc agctcttgtt gttgttggtg accacaatgg
    69001 tcgcgtagga tttggtactg gtaaagctca agaagttcca gaagcaatcc gtaaagcagt
    69061 agatgatgct aagaaaaact tgatcgaagt tcctatggtt ggaacaacaa tcccacacga
    69121 agttctttca gaattcggtg gagctaaagt attgttgaaa cctgctgtag aaggttctgg
    69181 agttgccgct ggtggtgcag ttcgtgccgt tgtggaattg gcaggtgtgg cagatattac
    69241 atctaaatca cttggttcta acactccaat caacattgtt cgtgcaactg ttgaaggttt
    69301 gaaacaattg aaacgcgctg aagaaattgc tgcccttcgt ggtatttcag tttctgattt
    69361 ggcataagaa aggggataaa atggctcaaa ttaaaattac tttgactaag tctccaatcg
    69421 gacgcattcc atcacaacgt aaaactgttg tagcacttgg acttggcaaa ttgaacagct
    69481 ctgttattaa agaagataac gctgctatcc gtggtatgat cacagcagta tctcacttag
    69541 taacagttga agaagtaaac taatgaagtt ttaggggatg tgcactgtac catcccctaa
    69601 aactagatat agtcatctat gatgacatcg tataggcgag ttgatggggg agacaacctt
    69661 ttctccctta tcggcgctag cattttacaa aagaggagaa aataaaaatg aaacttcatg
    69721 aattgaaacc tgcagaaggt tctcgtaaag tacgtaaccg cgttggtcgt ggtacttcat
    69781 caggtaacgg taaaacatct ggtcgtggtc aaaaaggtca aaaagctcgt agcggtggcg
    69841 gagttcgcct tggttttgaa ggtggacaaa ctccattgtt ccgtcgtctt ccaaaacgtg
    69901 gattcactaa catcaacgct aaagaatacg caattgtgaa ccttgaccaa ttgaacgtct
    69961 ttgaagatgg tgctgaagta actccagttg ttcttatcga agcaggaatt gttaaagctg
    70021 aaaagtcagg tattaaaatt cttggtaacg gtgagttgac taagaaattg actgtgaaag
    70081 cagctaaatt ctctaaatca gctgaagaag ctatcactgc taaaggtggt tcagtagaag
    70141 tcatctaaga gaggtgacct atgtttttta aattattaag agaagctctt aaagtcaagc
    70201 aggttcgatc aaaaatttta tttacaattt ttatcgtttt ggtctttcgt atcggaacta
    70261 gcattacagt tcctggtgtg aatgccaata gcttgaatgc tttaagtgga ttatccttct
    70321 taaacatgtt gagcttggtg tcggggaatg ccctaaaaaa cttttcgatt tttgccctag
    70381 gagttagtcc ctatatcacc gcttctattg ttgtccaact cttgcaaatg gatattttac
    70441 ccaagtttgt agagtggggt aaacaagggg aagtaggtcg aagaaaattg aatcaagcta
    70501 ctcgttatat tgctctagtt ctcgcttttg tgcaatctat cgggattaca gctggtttta
    70561 ataccttggc tggagctcaa ttgattaaaa ctgctttaac tccacaagtt tttctgacga
    70621 ttggtatcat cttaacagct ggtagtatga ttgtcacttg gttgggtgag caaattacag
    70681 ataagggata cggaaacggt gtttccatga ttatctttgc cgggattgtt tcctcaattc
    70741 cagagatgat tcagggcatc tatgtggact actttgtgaa cgtcccaagt agccgtatca
    70801 cttcatctat cattttcgta atcattttga ttattactgt attgttgatt atttacttta
    70861 caacttatgt tcaacaagca gaatacaaaa ttccaatcca atatactaag gttgcacaag
    70921 gtgctccatc tagctcttac cttccgttaa aggtaaatcc tgctggagtt atccctgtta
    70981 tctttgccag ttcgattact gcagcgcctg cggctattct tcagtttttg agtgccacag
    71041 gtcatgattg ggcttgggta agggtagcac aagagatgtt ggcaactact tctccaactg
    71101 gtattgccat gtatgctttg ttgattattc tctttacatt cttctatacg tttgtacaga
    71161 ttaatcctga aaaagcagca gagagcctac aaaagagtgg tgcctatatc catggagttc
    71221 gtcctggtaa aggtacagaa gaatatatgt ctaaacttct tcgtcgtctt gcaactgttg
    71281 gttccctctt ccttggtgtg atttccattt taccgattgc agctaaagat gtatttggtc
    71341 tttctgatgt tgttgccttt ggtggaacaa gtctcttgat cattatctct acaggtatcg
    71401 aaggaatcaa gcaattggaa ggttacctat tgaaacgtaa gtatgttggt ttcatggaca
    71461 gaacagaata aaagtattta ctgaatcagt aaatactgag ggagtggagg tttaaactct
    71521 gacatttgta agagttggat ctcccctctt ctattttgtt tttaaatcgg ggtgaaaaaa
    71581 ctttttgctt ctatttaaaa acaaaataag gagatcaaat tatgaatctt ttgattatgg
    71641 gcttacctgg tgcaggtaag ggaactcaag cagcaaaaat cgtagaacaa ttccatgttg
    71701 cacatatctc aacaggtgat atgttccgcg ctgcaatggc aaatcaaact gaaatgggtg
    71761 ttcttgctaa gtcatatatt gacaagggtg aattggttcc tgacgaagtt acaaatggaa
    71821 tcgtaaaaga acgcctttca caagatgata ttaaagaaac aggattctta ttggatggtt
    71881 acccacgtac aattgaacaa gctcatgcct tggacaaaac attggctgaa cttggcattg
    71941 aactagaagg tattatcaat attgaagtta accctgacag cctcttggaa cgtttgagtg
    72001 gccgtatcat ccaccgcgta actggagaaa ctttccacaa ggtctttaac ccaccagttg
    72061 actataaaga agaagattac taccaacgtg aagatgataa gcctgagaca gtaaaacgtc
    72121 gtttggatgt taatattgct caaggagaac caatcattgc tcactaccgt gccaaaggtt
    72181 tggttcatga catcgaaggt aatcaagata tcaatgatgt cttctcagat attgaaaaag
    72241 tattgacaaa tttgaaataa agcgtttttc acacttgcaa aaatccgcta caaatgttat
    72301 actgaaatag tctgacttat aattgttgtc tctgtgtcta gaggcatcga atcgaaattt
    72361 atggaggtgc ttttgcgtgg caaaagacga tgtgattgaa gttgaaggca aagtagttga
    72421 tacaatgccg aatgcaatgt ttacggttga acttgaaaat ggacatcaga ttttagcaac
    72481 agtttctggt aaaattcgta aaaactatat tcgtatttta gcgggagatc gtgttactgt
    72541 cgaaatgagt ccatatgact tgacacgtgg acgtatcact taccgcttta aataatcgaa
    72601 aaacttggag ggataagaaa tgaaagtaag accatcggtc aaaccaattt gcgaatactg
    72661 taaagttatt cgtcgtaatg gtcgtgttat ggtaatttgc ccagcaaatc caaaacacaa
    72721 acaacgtcaa ggataagata gaaaggagaa aacatggctc gtattgctgg agttgatatt
    72781 ccaaatgaca aacgcgtagt aatctcattg acttatgttt atggtatcgg acttgcaaca
    72841 tctaagaaaa ttttggctgc tgctggaatc tcagaagatg ttcgtgtacg tgatcttaca
    72901 tcagatcaag aagatgctat ccgtcgtgaa gtggatgcaa tcaaagttga aggtgacctt
    72961 cgtcgtgaag taaacttgaa catcaaacgt ttgatggaaa tcggttcata ccgtggtatc
    73021 cgtcaccgtc gtggacttcc tgtccgtgga caaaatacta aaaacaacgc tcgcactcgt
    73081 aaaggtaaag ctgttgcgat tgctggtaag aaaaaataat ataggaggta aaagtcttgg
    73141 ctaaaccaac acgtaaacgt cgtgtgaaaa agaatatcga atctggtatt gctcatattc
    73201 acgctacatt taataacact attgttatga ttactgatgt gcatggtaat gcaattgctt
    73261 ggtcatcagc tggtgctctt ggtttcaaag gttctcgtaa atctacacca ttcgctgctc
    73321 aaatggcttc tgaagctgct gctaaatctg cacaagaaca cggtcttaaa tcagttgaag
    73381 ttactgtaaa aggtccaggt tctggtcgtg agtcagctat tcgtgcgctt gctgccgctg
    73441 gtcttgaagt aacagcaatt cgtgatgtga ctccagtgcc acacaatggt gctcgtcctc
    73501 caaaacgtcg ccgtgtataa tcatcgcatt acactgcttt tcgtttaaga gggagtaact
    73561 aaatgatcga gtttgaaaaa ccaaatataa caaaaattga tgaaaataaa gattatggca
    73621 agtttgtaat cgaaccactt gaacgtggct acggtacaac tcttggtaac tctcttcgtc
    73681 gtgtacttct agcttctcta ccaggagcag ctgtgacatc tatcaacatt gatggtgtgt
    73741 tacatgagtt tgacacagtt ccaggtgttc gtgaagacgt gatgcaaatc attctgaaca
    73801 ttaagggaat tgcagtgaaa tcgtacgttg aagacgaaaa aatcatcgaa ctggatgttg
    73861 aaggtcctgc tgaagtaaca gctggtgaca ttttgacaga tagcgatatt gaaattgtaa
    73921 atccagatca ttatctcttt acaatcggtg aaggttcttc tctaaaagcg actatgactg
    73981 ttaacagtgg tcgtggatat gtacctgctg acgaaaataa aaaggataat gcaccagttg
    74041 gaacacttgc tgtagattct atttatacac cagttacaaa agtcaactat caagtggaac
    74101 ctgctcgtgt aggtagcaat gatggtttcg acaaattaac ccttgaaatc ttgacaaatg
    74161 gaacaattat tccagaagat gctttagggc tttcagcacg tattttgaca gaacatcttg
    74221 atttgtttac aaatcttact gagattgcta agtcaactga agtgatgaaa gaagctgata
    74281 ctgaatctga cgaccgtatt ttagatcgta cgattgagga actggacttg tctgtgcgtt
    74341 catacaactg tttaaaacgt gccggtatca atactgtgca tgatttgaca gaaaaatctg
    74401 aagcagagat gatgaaagta cgaaatcttg gacgcaagag tttggaagaa gtgaaactca
    74461 aactcattga tttgggtctt ggattaaaag ataaataaag gaggaataca tggcttaccg
    74521 taaactagga cgcactagct cacaacgtaa agcaatgctt cgcgatttga caactgacct
    74581 tttgatcaac gaatcaatcg tgacaactga agctcgtgct aaagaaatcc gtaaaactgt
    74641 tgaaaaaatg attactctag gtaaacgtgg tgatttgcat gcacgtcgtc aagcagctgc
    74701 tttcgtacgt aatgaaatcg catctgaaaa ctatgatgaa gcaactgata agtacacttc
    74761 tactacagca cttcaaaaat tgttctcaga aatcgcacct cgttatgctg aacgtaacgg
    74821 tggatacact cgtatcctta aaactgaacc acgtcgtggt gatgcagcgc caatggcgat
    74881 catcgaatta gtataaaatc atcaattttg ttgagtgtta tgatgatgga gtcttgtgct
    74941 cttagtctag ctctggtcta ccgctaggat ttcggtccta gcgggaacac tcatcataag
    75001 ttgggatagt agacgcttgt ttacgaaatt gtttttttct taagaacaac ttcgtaagca
    75061 ggcgtttttg agtattttcg ttagaattat gctatactat ttgaaaagaa tcctgtttaa
    75121 tgttaaggtt tcttatttta agaagaattg gagtttactt atgaaagcca ttataactgt
    75181 tgttggtaaa gataaatctg gaattgttgc aggtgtttct ggtaaaattg cagaattagg
    75241 attgaatatt gacgatatct ctcaaactgt attggatgaa tattttacga tgatggctgt
    75301 tgtatctagt gatgaaaagc aagattttac ctatcttcgt aatgaatttg aagcttttgg
    75361 gcaaactttg aatgtaaaaa tcaatattca gagtgcagcg attttcgaag ctatgtataa
    75421 tatctaggag gtcatcatgg atattagaca agttactgaa accatcgcca tgattgagga
    75481 gcaaaacttc gatattagaa ccattaccat ggggatttct cttttggact gtatcgatcc
    75541 aaatatcaat cgtgctgcgg agaaaatcta tcaaaaaatt acgacaaagg cggctaattt
    75601 agtagctgtt ggtgatgaaa ttgcggctga gttgggaatt cctatcgtta ataagcgtgt
    75661 atcggtgaca cctatttctc tgattggggc agcgacagat gcgacggact acgtggttct
    75721 ggcaaaagcg cttgataagg ctgcgaaaga gattggtgtg gactttattg gtggtttttc
    75781 tgccttagta caaaaaggtt atcaaaaggg agatgagatt ctcatcaatt ccattcctcg
    75841 cgctttgact gagacggata aggtctgctc gtcagtcaat atcggctcaa ccaagtctgg
    75901 tattaatatg acggctgtgg cagatatggg acgaattatc aaggaaacgg caaatctttc
    75961 agatatggga gcggccaagt tggttgtatt cgctaatgct gttgaggaca atccatttat
    76021 ggcgggtgcc tttcatggtg ttggggaagc agatgttatc atcaatgtcg gagtttctgg
    76081 tcctggtgtg gtgaaacgtg ctttggaaaa agttcgtgga cagagctttg atgtagtagc
    76141 cgaaacagtt aagaaaactg cctttaaaat cactcgtatc ggtcaattgg ttggtcaaat
    76201 ggccagtgag agactgggtg tggagtttgg tattgtggac ttgagtttgg caccaacccc
    76261 tgcggttgga gactctgtgg cacgtgtcct tgaggaaatg gggctagaaa cagttggcac
    76321 gcatggaacg acggctgcct tggccctctt gaacgaccaa gttaaaaagg gtggagtgat
    76381 ggcctgcaac caagtcggtg gtttatctgg cgcctttatc cctgtttctg aggatgaagg
    76441 aatgattgct gcagtgcaaa atggctctct taatttagaa aaactagaag ctatgacggc
    76501 tatctgttct gttggattgg atatgattgc catcccagaa gatacgcctg ctgaaaccat
    76561 tgcggctatg attgcggatg aagcagcaat cggtgttatc aacatgaaaa caacagctgt
    76621 tcgtatcatt cccaaaggaa gagaaggcga tatgattgag tttggtggtc tattaggaac
    76681 tgcacctgtt atgaaggtta atggggcttc gtctgtcgac ttcatctctc gcggtggaca
    76741 aatcccagca ccaattcata gttttaaaaa ttaagaaaat aggagaaatt ttaagttcta
    76801 tttaagatta gatgtgtata ctataatcat taaataaaga cctcctaata ttatttgaaa
    76861 cagataacac tgaattagtt tgaatttgat tttcatctaa tatctttatt taatgaactc
    76921 ctaaactttt tcataataat ctccttcaaa agtcgcctgt atgggtggct tttattttat
    76981 cattcatgat ataatagaag caaacggagg acggaaaatg gtaaaagtac gattgtattt
    77041 ggtacgtcat ggcaagacca tgtttaacac gattggtcgc gcgcaaggtt ggagcgatac
    77101 tcccttaact gctgaaggtg aacgagggat tcaagagtta ggaatcggtt tgcgagaatc
    77161 tgatctacag tttgagcgcg cttattcgag tgattctggt cgtaccattc agaccatggg
    77221 aattatcctt gaagaacttg gcttgcaggg gaaaatccct tatcgcatgg acaagcgtat
    77281 cagagaatgg tgtttcggta gttttgatgg agcctatgat ggcgatcttt tcatgggcat
    77341 tattcctcgt atctttaatg tggaccacgt tcaccaattg tcttatgctg aactggctga
    77401 gggcttggta gaggtcgata cagctggttg ggctgaaggc tgggaaaaac tcagtggccg
    77461 aatcaaggaa ggctttgaaa tgattgcaaa agaaatggaa gatcaaggtg gaggtaacgc
    77521 ccttgttgtc agccatggaa tgactattgg aaccattgtt tatctgatta atggcatgca
    77581 tccgcatggt ctagataatg gtagcgtgac gattcttgaa tatgaggatg gtcagtttag
    77641 ggttgaagtt gtcggtgacc gtagttaccg agagctagga cgtgagaaga tggaagaagg
    77701 ctctatttaa tcagtctaga cttgcttgcc atgagctagg gatttgataa gaatatcaag
    77761 ataagaaaaa acagccgagg gtactccttt cggctgtttt tgatgtggaa aactaaagtg
    77821 taatgctatt gcttttagag attttcataa acaagagcaa ggaacctact gttagaacag
    77881 tcaggatagt tgacaaggct gcggctacac cataatttcc tctgagaacc tctgtataaa
    77941 tagctacagt cattgttctt gttttgacat tgtagaggag gatagaagta gagagttttg
    78001 aaatcattgt gacccaagat aagatggctc cagaaatgat accagatagc atcattggag
    78061 ttgtaatctt agcaaaggta ttgagacgac tacttcctaa gctttcagca gcttcttcaa
    78121 tacttggtgc tatttgttgt aagctagcaa cagatgagcg aatagtataa ggtaatcttc
    78181 tgacagatag agacataatc aagatgaaag cagtccctgt aatcataaga aatccacttc
    78241 caaatagacc agagaaatga aggcaatccc tagaacggtt cctggtacaa tataaggtac
    78301 catactgagg ctgtcaatta agtttgtaaa caaattccgt tttctaacgg ctaggtagga
    78361 gataaatgtc gcaaatagaa caactagaac taaggcaatc aaagggatac gaatggtatt
    78421 gaaaatagca gatcccatac gattgaaagc tagcttgtaa ctgtttggag aataaccttt
    78481 aacaaatacc atacctgatg tttttaggaa agaggtataa attaagtaga tttgaggtaa
    78541 aacagagata aagataattc cgtagactgt tgcataaatg gcagccattt ttccttttgt
    78601 agttttttta ggctcaattg gatggagcag attcatgctg aaactgtagc ggtttgcaat
    78661 gtgtttttgg ataaggaaaa ttgccaaggc aatgataatc gccataattg caaaagcaga
    78721 atttcctcca acctcgctaa taaattgggt ataaatcagg acagggaaag tccgatatcc
    78781 ttcgccaatc aacataggcg ttccaaagtc tgagaatgct ctcataaata caagcaagga
    78841 gctgctagta aggttggaac taggagaggt aaaacaaccg ttacgatagg tttaaatccg
    78901 aaggacccca tgctttcagc tgcttcaagt agagaattgt caatactgtt cattgttcca
    78961 gcaacatata gaaataccag tgggaatagt tgcagtgtaa agacaagtac aattcctttg
    79021 aatccataaa tatcgatagc tggaagatga agggcatttg tcaaaaattt agtgatgacc
    79081 tcatttcgtc tcagcaagag aatccaggag taggctccta cgaaaggagt tgacatggaa
    79141 gcaatgataa tcaatatttg tagaaatttc ttccccttga agtcatacat agagaagaga
    79201 taagctaata gggttcctac aactaaggaa gtgacagtag cggtaatgga aaccctgaaa
    79261 ctgttgacta gtgtctcaga gtagtaggtt ttactaaaga aagtgacaaa attagctagt
    79321 gagaattatc cttcatgtat aagtgcttac ttgagcacgg taacgatagg ataaacgaga
    79381 aagacaagat aggtaagaaa gatgaagaaa gaggaggctg tccaaatatt tagtttttta
    79441 cgttccatgg ttgactcctt ttatcaggtt ttgggaacca tctgcagaaa agatgtttaa
    79501 tttttgcgta ttgattcgta gacgaatacg attgtctttt tgtagatctt cttcaaaagt
    79561 tgattcttca ctaacttgaa tttttgaggc aaaacctgtc tcaatgaaat actccgtatt
    79621 tagtccaaga tagacgctat cgctaatagt tccttcgata tctccagatt catctttgat
    79681 aaactcttcg ggacgaatgc ttacatgaat agcttgctcc tcaacctgat caagagctag
    79741 cattcgaagg gcatagccat ctgaaaagac gatataagcg ccgtcgctcc gtttttcaag
    79801 attggcaggg ataatatttg tgcgtccgat aaaggttgcc acaaactcat tagctggttt
    79861 atgatagagt tcttttggtc ggccgatttg ttggatcacc ccatctttca taacagcaat
    79921 ttggtctgaa atagccatgg cttcttcttg gtcgtgggtt acataaacag ttgtaattcc
    79981 cacttcgtgt tggatttctc ggatggtttg acgcatatcc aagcgaagtt tggcctccag
    80041 attactaagt ggctcgtcca tgaggagaac acttggatta accgctaagg cgcatgccaa
    80101 ggtgacacgt tgttgttgtc caccactgac tttatcgggc tttcaatccg catattgagc
    80161 aatttgcatg agttcaagat acttgttggt ctgttgaatc aattcttctt ttggaacctt
    80221 cttttgcata agaccaaaag caacgttgtc tcggacagtc aaatgtggga aaatagcgta
    80281 gttttggaaa accatcccga tattgcgttt gctgggttcc atattattga tttttgtatc
    80341 atcgaagtaa aattctccat ctttgatact gttgaaacct gcaatcatac gaagaagggt
    80401 cgttttccca catcctgaag ctccaagaag ggtaaagaga cttccttttg gaattgtaat
    80461 gttcaaattc tcaataacag ggacatcgtg gtagattttt ttggcgttaa taatttcgat
    80521 ctcactcata gtgaacctct tttactgttt agattggata tctgtaaaga cttcgttgta
    80581 tttcttaacg atatctgatt tattcttgat gacataatca taatcttcag tgagtgtttt
    80641 gattttgtca attggtttca tgttttcgct tgttttagca tttttacgaa caggacggtt
    80701 agtagtggtt gtaccaagtg tatcttgtac ttcttgagag ataataaaat cgataaattt
    80761 cttggcattt tccatatttt tagctttttt aacgatagca gcactagcag gtaggaagac
    80821 ggttccttct tttggataga ctaccttaat gttagctccg tcatttaaga gtttaactgc
    80881 tggatcctca taagagagac caacagccat ttctccatca gcgactgctt tatagacacc
    80941 agatgaactt aaaccgattt tatagtatat tgaaactaga atagtacacg tctacttcta
    81001 aaacattgtt agaaatcgat ttgactgtcc tgattaattt gtcctgttct tatttcattt
    81061 tactatacca tcaataagtg tgaaaagatc ttttacataa gaccaagcct tatcatcttt
    81121 gtaaccacct tgagcttgta gcatatttgt taattgagca aaggcgctag aagagtttgc
    81181 tgggtcggca gttgcgattt ttccttttag ttcaggtttg agaagatcgt tatatccttc
    81241 gatgttcatg cctttagtta aatcagggtt gacgattaaa acactaccat ctagtgtata
    81301 aggagtagag tagccagttg tgttttgata ttctttgata acattatcat tttcttttga
    81361 agtatagttt tcaaagagtt ctccgtgggt agcatattgt gtataagaac caccaaagat
    81421 aacatcagct acaggaactt ctttttctga ctctagtttt ttgaaaagtt ctccagtacc
    81481 agcttgaatc agttctactt tgataccata tttttcttca aaggcaggaa tagttgctcc
    81541 aattaagtcc tctgagtttg gtcaataaac gactagcgaa ccaccgtctc ctttatcaga
    81601 tgaactgtca tcggcagatt cattagaaga acaagcagca taatacatcc atttcttttt
    81661 catgatggga tatctccgtt gtgttattta agtttatttt aaaacctaca attctattct
    81721 atagt
//
LOCUS       DAVHSY010000005        81687 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.005, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000005 DAVHSY010000000
VERSION     DAVHSY010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 81687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81687
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.005"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            135..1616
                     /locus_tag="VVR43_000416"
     CDS             135..1616
                     /locus_tag="VVR43_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6148828.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            1978..2979
                     /locus_tag="VVR43_000417"
     CDS             1978..2979
                     /locus_tag="VVR43_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6148829.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILKKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3130..4047
                     /locus_tag="VVR43_000418"
     CDS             3130..4047
                     /locus_tag="VVR43_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6148830.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4058..4948
                     /locus_tag="VVR43_000419"
     CDS             4058..4948
                     /locus_tag="VVR43_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6148831.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            4977..6593
                     /locus_tag="VVR43_000420"
     CDS             4977..6593
                     /locus_tag="VVR43_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6148832.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFTFISGNGNEDFKFLFAAFDIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6603..7922
                     /locus_tag="VVR43_000421"
     CDS             6603..7922
                     /locus_tag="VVR43_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU6148833.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVVTGTDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAVKHMDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8132..8204)
                     /locus_tag="VVR43_000422"
     tRNA            complement(8132..8204)
                     /locus_tag="VVR43_000422"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8169..8171),aa:Lys,seq:ctt)
     gene            complement(8469..9740)
                     /locus_tag="VVR43_000423"
     CDS             complement(8469..9740)
                     /locus_tag="VVR43_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU6148834.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALTDLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            10010..10249
                     /locus_tag="VVR43_000424"
     CDS             10010..10249
                     /locus_tag="VVR43_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148835.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVYSNNGLKKYEK"
     gene            10414..10593
                     /locus_tag="VVR43_000425"
     CDS             10414..10593
                     /locus_tag="VVR43_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148836.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10730..10909
                     /locus_tag="VVR43_000426"
     CDS             10730..10909
                     /locus_tag="VVR43_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU6148837.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            10946..11398
                     /locus_tag="VVR43_000427"
     CDS             10946..11398
                     /locus_tag="VVR43_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU6148838.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11689..12159
                     /locus_tag="VVR43_000428"
     CDS             11689..12159
                     /locus_tag="VVR43_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU6148839.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNYAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDALMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPKY"
     gene            12178..13266
                     /locus_tag="VVR43_000429"
     CDS             12178..13266
                     /locus_tag="VVR43_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEU6148840.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAILFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVRKDVVQTHKAMKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            13247..13405
                     /locus_tag="VVR43_000430"
     CDS             13247..13405
                     /locus_tag="VVR43_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HEU6148841.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     KSVRENLI"
     gene            13515..14549
                     /locus_tag="VVR43_000431"
     CDS             13515..14549
                     /locus_tag="VVR43_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU6148842.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGISK
                     SSVSRELSED"
     gene            14611..16794
                     /locus_tag="VVR43_000432"
     CDS             14611..16794
                     /locus_tag="VVR43_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HEU6148843.1"
                     /translation="MGPITIPKKTIITLEHLKYLHFSLEETKTYWEKNNIIDGILISI
                     YYNRIVAKSNRINGYFNVGGGNPFPNDTIVGAKFNDEKTKHIVTHYISRDALNKTITV
                     LSKIIEVFEEHFDRAITCEMFSDSSTFASINFSEYGISKSKFQQYLRDSCFIENFGVE
                     HTTVSDIQNSIVTFYDVHTDIFRLLNKLNIDISEANIMNQTTVLLDEKNIELLLSKAP
                     YLVSMIVEDFSKLSVDDFSLDNNDLKINLPSPMNEPVVGVIDTLFDKRVYFNEWVEYH
                     DFVSPDISKDSQDYKHGTAVTSLIVDGANLNPNLDDGCGNFRVRHFGVSLQSGFNSFT
                     IIKQIKEIVSQNADIKVWNLSLGSNDEIRENFISAEGALLDEIQFENDVIFIIAGTNA
                     SVINGKRKRIGAPADSLNSIIVNSVDFNNQSVSYSREGIVLSFFVKPDVSYYGGGNGD
                     FINVCEPLGLGRVAGTSFAAPFIARKMAYLIHIMGLSREEAKALLIDAAIPWNDKKTF
                     TDLSLIGNGIVPIKMDDILSTPDDEIKFIVSDISRAYDTYNYDFPVPISSESYPYVAK
                     ATMCYFPNCSRKQGVDYTNTEMQLTFGRLKSDGIKSINKDNQHAEDTPGYVRENAARN
                     IFRKWDNVKHIGESFTSRKRAKAILNPSNPQWGMSIKTIERLKSGDGQGVRFGVVVTL
                     KELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSLNEEIEFE"
     gene            16845..17861
                     /locus_tag="VVR43_000433"
     CDS             16845..17861
                     /locus_tag="VVR43_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU6148844.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYRDFYEFQNKVYISRTENEEKYSN
                     FIYESLFSDKVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEVVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDDMRTSLPVINQPAIDKKYNENPHQDDIVNIVTLNYT
                     HVIDKLYNGSAKSFRNQLRANLYNFYIEPPIHAHGTVDVCTVLGVSDEIQISNSLEEQ
                     KESLIKSLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDRYIWSQIAERSISGSV
                     PVIIYHYVPHFDPGNPIRAKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIFD
                     LIER"
     gene            17876..18826
                     /locus_tag="VVR43_000434"
     CDS             17876..18826
                     /locus_tag="VVR43_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU6148845.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSLDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            18828..19571
                     /locus_tag="VVR43_000435"
     CDS             18828..19571
                     /locus_tag="VVR43_000435"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU6148846.1"
                     /translation="MQQYFVKGSAISPVTIEDKEISKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            19582..21378
                     /gene="pepF"
                     /locus_tag="VVR43_000436"
     CDS             19582..21378
                     /gene="pepF"
                     /locus_tag="VVR43_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU6148847.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            21624..22178
                     /locus_tag="VVR43_000437"
                     /pseudo
     CDS             21624..22178
                     /locus_tag="VVR43_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
     gene            22289..22957
                     /locus_tag="VVR43_000438"
     CDS             22289..22957
                     /locus_tag="VVR43_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEU6148848.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGYLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(23047..23385)
                     /locus_tag="VVR43_000439"
     CDS             complement(23047..23385)
                     /locus_tag="VVR43_000439"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148849.1"
                     /translation="MLKAVFEVIDKTDEVSLKHCFEVADRTDEVSLKHCFEVADRTDE
                     VSLKHCFEVADRTDEVSLKHCFEVVDETDEVSLKHCFEVVDETDEVSLKHCFEVADRT
                     DEVSNIYTTR"
     gene            complement(23435..23968)
                     /gene="queF"
                     /locus_tag="VVR43_000440"
     CDS             complement(23435..23968)
                     /gene="queF"
                     /locus_tag="VVR43_000440"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU6148850.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQHHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(24273..24587)
                     /gene="trxA"
                     /locus_tag="VVR43_000441"
     CDS             complement(24273..24587)
                     /gene="trxA"
                     /locus_tag="VVR43_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU6148851.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(24604..24825)
                     /locus_tag="VVR43_000442"
     CDS             complement(24604..24825)
                     /locus_tag="VVR43_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU6148852.1"
                     /translation="MIEITYLDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(24924..25304)
                     /locus_tag="VVR43_000443"
     CDS             complement(24924..25304)
                     /locus_tag="VVR43_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU6148853.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(25447..26400)
                     /locus_tag="VVR43_000444"
     CDS             complement(25447..26400)
                     /locus_tag="VVR43_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU6148854.1"
                     /translation="MSISQRTTKLILATCLAYLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(26468..27676)
                     /gene="sstT"
                     /locus_tag="VVR43_000445"
                     /pseudo
     CDS             complement(26468..27676)
                     /gene="sstT"
                     /locus_tag="VVR43_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            27815..28375
                     /locus_tag="VVR43_000446"
     CDS             27815..28375
                     /locus_tag="VVR43_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEU6148855.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            28432..29340
                     /locus_tag="VVR43_000447"
     CDS             28432..29340
                     /locus_tag="VVR43_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU6148856.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIG
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            29292..29882
                     /locus_tag="VVR43_000448"
     CDS             29292..29882
                     /locus_tag="VVR43_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU6148857.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            29885..30991
                     /gene="yqeH"
                     /locus_tag="VVR43_000449"
     CDS             29885..30991
                     /gene="yqeH"
                     /locus_tag="VVR43_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU6148858.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVIRKAII"
     gene            31205..31516
                     /gene="yhbY"
                     /locus_tag="VVR43_000450"
     CDS             31205..31516
                     /gene="yhbY"
                     /locus_tag="VVR43_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU6148859.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            31568..32197
                     /locus_tag="VVR43_000451"
     CDS             31568..32197
                     /locus_tag="VVR43_000451"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU6148860.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            32197..32790
                     /gene="yqeK"
                     /locus_tag="VVR43_000452"
     CDS             32197..32790
                     /gene="yqeK"
                     /locus_tag="VVR43_000452"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU6148861.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            32791..33291
                     /locus_tag="VVR43_000453"
     CDS             32791..33291
                     /locus_tag="VVR43_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU6148862.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            33304..33657
                     /gene="rsfS"
                     /locus_tag="VVR43_000454"
     CDS             33304..33657
                     /gene="rsfS"
                     /locus_tag="VVR43_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU6148863.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            33760..34506
                     /locus_tag="VVR43_000455"
     CDS             33760..34506
                     /locus_tag="VVR43_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6148864.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKITFIEGNMLNLSNAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            34516..35613
                     /locus_tag="VVR43_000456"
     CDS             34516..35613
                     /locus_tag="VVR43_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU6148865.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGTEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARENVLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            35851..36081
                     /locus_tag="VVR43_000457"
     CDS             35851..36081
                     /locus_tag="VVR43_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEU6148866.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMDKIRAGH"
     gene            36350..37963
                     /locus_tag="VVR43_000458"
     CDS             36350..37963
                     /locus_tag="VVR43_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU6148867.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLINEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            38093..38719
                     /gene="gmk"
                     /locus_tag="VVR43_000459"
     CDS             38093..38719
                     /gene="gmk"
                     /locus_tag="VVR43_000459"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU6148868.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVSLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            38744..39058
                     /locus_tag="VVR43_000460"
     CDS             38744..39058
                     /locus_tag="VVR43_000460"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU6148869.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            39124..41520
                     /locus_tag="VVR43_000461"
     CDS             39124..41520
                     /locus_tag="VVR43_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU6148870.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLVLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            41533..42468
                     /locus_tag="VVR43_000462"
     CDS             41533..42468
                     /locus_tag="VVR43_000462"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU6148871.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            42461..43774
                     /gene="rsmB"
                     /locus_tag="VVR43_000463"
     CDS             42461..43774
                     /gene="rsmB"
                     /locus_tag="VVR43_000463"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU6148872.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNALLRRILREGWPDISSIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            43789..44529
                     /locus_tag="VVR43_000464"
     CDS             43789..44529
                     /locus_tag="VVR43_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU6148873.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            44526..46505
                     /gene="pknB"
                     /locus_tag="VVR43_000465"
     CDS             44526..46505
                     /gene="pknB"
                     /locus_tag="VVR43_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU6148874.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            46620..47378
                     /locus_tag="VVR43_000466"
     CDS             46620..47378
                     /locus_tag="VVR43_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU6148875.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            47380..47829
                     /locus_tag="VVR43_000467"
     CDS             47380..47829
                     /locus_tag="VVR43_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU6148876.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            47891..48454
                     /locus_tag="VVR43_000468"
                     /pseudo
     CDS             47891..48454
                     /locus_tag="VVR43_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            48440..48643
                     /locus_tag="VVR43_000469"
     CDS             48440..48643
                     /locus_tag="VVR43_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148877.1"
                     /translation="MNLIAEKVSKTLDKTFDKDVREIPTSQFYQKFVDEMGRTYSGNL
                     ILQELITVNGAYKATYIGELSSN"
     gene            48774..49946
                     /locus_tag="VVR43_000470"
     CDS             48774..49946
                     /locus_tag="VVR43_000470"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU6148878.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTVLSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            49946..51220
                     /locus_tag="VVR43_000471"
     CDS             49946..51220
                     /locus_tag="VVR43_000471"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU6148879.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(51255..52220)
                     /locus_tag="VVR43_000472"
     CDS             complement(51255..52220)
                     /locus_tag="VVR43_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6148880.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILIIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(52201..53655)
                     /locus_tag="VVR43_000473"
     CDS             complement(52201..53655)
                     /locus_tag="VVR43_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU6148881.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLIHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFIEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            54032..55915
                     /locus_tag="VVR43_000474"
     CDS             54032..55915
                     /locus_tag="VVR43_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU6148882.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVVHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            56064..56951
                     /locus_tag="VVR43_000475"
     CDS             56064..56951
                     /locus_tag="VVR43_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6148883.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGENIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(57271..57888)
                     /locus_tag="VVR43_000476"
     CDS             complement(57271..57888)
                     /locus_tag="VVR43_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU6148884.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQVGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(58303..58522)
                     /locus_tag="VVR43_000477"
                     /pseudo
     CDS             complement(58303..58522)
                     /locus_tag="VVR43_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(59007..59087)
                     /locus_tag="VVR43_000478"
                     /pseudo
     CDS             complement(59007..59087)
                     /locus_tag="VVR43_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            59204..60097
                     /locus_tag="VVR43_000479"
     CDS             59204..60097
                     /locus_tag="VVR43_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6148885.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            60094..61293
                     /locus_tag="VVR43_000480"
     CDS             60094..61293
                     /locus_tag="VVR43_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6148886.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(61646..62413)
                     /locus_tag="VVR43_000481"
     CDS             complement(61646..62413)
                     /locus_tag="VVR43_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148887.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(62430..63125)
                     /locus_tag="VVR43_000482"
     CDS             complement(62430..63125)
                     /locus_tag="VVR43_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6148888.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(63130..63495)
                     /locus_tag="VVR43_000483"
     CDS             complement(63130..63495)
                     /locus_tag="VVR43_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6148889.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            63635..64108
                     /gene="nrdR"
                     /locus_tag="VVR43_000484"
     CDS             63635..64108
                     /gene="nrdR"
                     /locus_tag="VVR43_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU6148890.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            64109..65278
                     /locus_tag="VVR43_000485"
     CDS             64109..65278
                     /locus_tag="VVR43_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU6148891.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRRLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            65279..66175
                     /gene="dnaI"
                     /locus_tag="VVR43_000486"
     CDS             65279..66175
                     /gene="dnaI"
                     /locus_tag="VVR43_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU6148892.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            66172..66885
                     /locus_tag="VVR43_000487"
     CDS             66172..66885
                     /locus_tag="VVR43_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU6148893.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            66899..68209
                     /gene="der"
                     /locus_tag="VVR43_000488"
     CDS             66899..68209
                     /gene="der"
                     /locus_tag="VVR43_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU6148894.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            68300..68635
                     /locus_tag="VVR43_000489"
     CDS             68300..68635
                     /locus_tag="VVR43_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148895.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            68775..69110
                     /locus_tag="VVR43_000490"
     CDS             68775..69110
                     /locus_tag="VVR43_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148896.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     SLFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGVRH"
     gene            69295..70086
                     /locus_tag="VVR43_000491"
     CDS             69295..70086
                     /locus_tag="VVR43_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148897.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIVTYFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAVYFFKIVDYLGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            70079..70720
                     /locus_tag="VVR43_000492"
     CDS             70079..70720
                     /locus_tag="VVR43_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148898.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEVNLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLLVWFLGLLPLGIHFKTVALFFLFAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            70724..71374
                     /locus_tag="VVR43_000493"
     CDS             70724..71374
                     /locus_tag="VVR43_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6148899.1"
                     /translation="MKLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            71385..71672
                     /locus_tag="VVR43_000494"
     CDS             71385..71672
                     /locus_tag="VVR43_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148900.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            71818..74331
                     /gene="secA"
                     /locus_tag="VVR43_000495"
     CDS             71818..74331
                     /gene="secA"
                     /locus_tag="VVR43_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU6148901.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRK"
     gene            74412..75443
                     /locus_tag="VVR43_000496"
     CDS             74412..75443
                     /locus_tag="VVR43_000496"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU6148902.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            75445..76476
                     /locus_tag="VVR43_000497"
     CDS             75445..76476
                     /locus_tag="VVR43_000497"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU6148903.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            76515..76883
                     /locus_tag="VVR43_000498"
     CDS             76515..76883
                     /locus_tag="VVR43_000498"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU6148904.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            76873..77976
                     /locus_tag="VVR43_000499"
     CDS             76873..77976
                     /locus_tag="VVR43_000499"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU6148905.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            77995..80010
                     /gene="recG"
                     /locus_tag="VVR43_000500"
     CDS             77995..80010
                     /gene="recG"
                     /locus_tag="VVR43_000500"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU6148906.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLI
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLALIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            80327..81307
                     /locus_tag="VVR43_000501"
     CDS             80327..81307
                     /locus_tag="VVR43_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU6148907.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT        24651 a        15085 c        18207 g        23744 t
ORIGIN      
        1 atatattgtc tccgtagtgt tattatacga aataaaagat tttaggaaaa gtcgttatat
       61 catgctatac ctattctttg tggtataatt gcaagaggtt taatccgata atttataaag
      121 agagaaagat attcatgaga gatttattat ctaaaaaaag tcataggcaa ttagaattat
      181 tagaattatt atttgaacat aaacgttggt ttcatcgttc tgaactagca gagttattaa
      241 attgtacaga acgtgcagtc aaagatgatc tatcccatgt taaatctgct tttcctgact
      301 tgatttttca ttcttctact aatggtatac gcattattaa taccgatgat agtgatattg
      361 aaatggttta ccatcatttc tttaaacatt caactcattt ttcgatttta gaattcatct
      421 tctttaatga aggttgtcaa gctgagagta tttgtaaaga attttatatc agttcatctt
      481 cgctctatcg tattattagc caaatcaata aagtgattaa aaggcaattt caatttgaag
      541 tcagtctgac ccctgttcaa atcattggaa atgagagaga cattcgttac ttttttgcac
      601 aatatttttc agaaaaatat tatttcctag aatggccatt tgaaaatttt tcatcagagc
      661 cactatctca attgttagaa ttggtttata aggaaacaag ctttccaatg aatttgtcaa
      721 cgcatagaat gctaaagttg ctcctagtta cgaacctata tagaataaag tttggtcatt
      781 ttatggaagt agataaagat tcttttaacg accaaagttt ggatttttta atgcaggcag
      841 aaggaataga aggtgttgct cagagttttg aatcagaata caatatctct ttagatgaag
      901 aagttgtttg ccaattattt gtgtcttact ttcaaaaaat gtttttcata gatgaaagtc
      961 tctttatgaa atgcgtaaaa aaggatagtt atgttgaaaa atcttaccat ctattgagtg
     1021 attttattga tcagatttca gtcaagtatc agattgaaat ggagaataag gataatctga
     1081 tttggcatct gcataatacc gcacatctgt atcgtcaaga gttgtttact gagtttattt
     1141 tatttgatca aaaagggaat acaatcagga actttcaaaa tatttttcca aaatttgttt
     1201 cagatataaa aaaagagctt tctcactatt tagagactct tgaggtttgt tctagttcaa
     1261 tgatggtaaa tcatctatct tataccttca tcactcatac caaacatttg gtgattaatt
     1321 tgctacaaaa tcagcctaaa ctaaaggttt tagttatgag taattttgat cagtatcatg
     1381 caaaattcgt tgcagagaca ctttcttatt actgtagcaa taattttgaa ctggaagttt
     1441 ggactgaatt agaattatca aaggaatctt tagaagattc accttatgat atcattattt
     1501 ctaattttat tattcctcct attgaaaata agagactcat ctattcaaat aatataaaca
     1561 cggtctcact catatacttg ttaaatgcca tgatgtttat tcgattagat gagtaaccaa
     1621 aaataacaaa aaaacgctat ttcgcgtttg aactgtacct caaaagttag acagaaaaaa
     1681 tctaattttt ggggtgtttt tgttaagaaa agaccttcaa tcatttaagc aaaatgtaca
     1741 tctagattta tagccctcta aaactcttgc tttttttgta gaagatacga aaaaagccat
     1801 aaaaccaagg cttttcctgt tttatgtaga tgtttacaca tgaaaattga agtattttca
     1861 aaagctaatt ggagtgattt tattcatgat gggataaatg atctggccaa aaatgattga
     1921 gaaatagttg cttaaaaagc atttgcatga tactatatat tgaaaggagg tgataatatg
     1981 gtagaacaaa gaaaatcaat taccatgaaa gatgttgctt tagaagcagg agttagtgtt
     2041 ggaactgttt cacgtgtaat taataaagaa aaaggcatta aagaagtaac tttgaaaaaa
     2101 gtggaacaag cgattaaaac tttgaattac attccagatt actacgctag aggaatgaaa
     2161 aaaaatcgaa cagaaacgat tgcaatcatt gtaccaagta tctggcatcc cttcttttca
     2221 gaatttgcta tgcatgtgga aaatgaagtc tataagagaa ataacaaatt actcttatgt
     2281 tctatcaatg gtacaaatag agagcaagac tatctggaga tgttgcgtca taataaagtt
     2341 gatggagtgg ttgccattac ctatagtcca attgaacatt acttgacgtc aggaattccc
     2401 tttgttagta ttgaccgcac atactcagat attgccattc cttgtgtttc atcagataat
     2461 gatgcaggtg gaagagaagc agctaaacaa ttaattagta aaggatgtca gcatttagcc
     2521 tttgtgggcg gacataatac aaccattaat gaaaccaaac gtcgtagaat ttcatttgaa
     2581 aagtatgtcc aagagcataa aatacctctt agtatttttg atttggatga gacagttact
     2641 gactattatg gaaagctaga gagtttcttg gaagaaaatt cttctataga tggaattttt
     2701 acaatcaacg attttacagc tttggatgtg attgaaatac taaaaaaaaa tggcaaacgt
     2761 attcctcatg atgtccaaat tattggatac gatggaatta aaatggctgg agatagagat
     2821 tatctacttt caactattga acaaccattg gaagaaatgg caaaagaagc ggttcgtatt
     2881 ttgtttgata taattgatgg aaagactgtt aatttgcaga caatcctacc agtaaaattt
     2941 gttgaaggaa aaacaacaaa aaatgaaaat aagtcttgac agaaagcgct atcaatgata
     3001 gaatgaattc agataaaaag atttattttt aaaacaaaaa tgaaacgttt caaaaaaaga
     3061 aataaaaaga cagcgccaag cgctatcttt tatagaaaaa atgaaacgtt tcaaaaaaag
     3121 gaggttgcta tgaatagcaa agcgaagcaa gtttctcttt gggaaagaat caagaaacaa
     3181 aaactcttgt tattgatgac tgtccccggt ttagttttaa cctttatctt taaatacatc
     3241 cctatgtatg gggttttaat cgcatttaaa gattacaatc ctttaaaagg aattttaggg
     3301 agtgattgga ttggtttttc tgagtttaca aaattcatat cctctcccaa ctttggtatc
     3361 ttgttagcca acacattaaa attaagtatc tatggtttat tgcttggctt tttaccacca
     3421 atcattcttg cgattatgct caatcaactc ttgagtgaaa aagtcaaaaa acgaattcag
     3481 ctcattttat acgcaccaaa ctttatctca gtcgttgtta ttgtcggtat gattttcctc
     3541 ttcttttcag tgggaggacc aatcaacaat tttctttcta tgtttggaat gaaggctgac
     3601 ttcttgacaa atccagactt ctttagacct ttatacatct ttagtggtat ctggcaagga
     3661 atgggctggg cttcaacgct ctacacggca acattggtaa atgtagatcc agccttagta
     3721 gaagcagctc gactggatgg agccaatatc ttccaacgaa tctggcacat tgatattcca
     3781 gctcttaagc ctattatggt tatccaattt gttttagctg caggtggaat tatgaatgtc
     3841 ggatatgaaa aagcattctt gatgcagaca tcgttaaatt tgccaacttc tgaaattatc
     3901 tcgacatatg tctataaagt tggtcttgta tcaggagact attcttactc aacagcggtt
     3961 ggtttgttta atgcagtgat taacgtagta ttgcttgttg cagttaacca aatcgttaaa
     4021 cgcatgaata atggtgaagg aatttaagga ggaaagtatg aaaaattcga ttatggatac
     4081 aaaatttgat agacgtatct tactcttaaa taaaatcatt attgtcttta tcgttttgat
     4141 gactttgctt cctttacttt atatcgtcgt agcatccttt atggatccta aggttctggt
     4201 tagtagaggg attagcttta atccagccga ttggactgta gaaggttacc agcgtgtatt
     4261 cagtgaccaa tctattctaa gaggttttat caattctcta ctatactctt ttggatttgc
     4321 agctttaaca gtattgctat ctgtgtttac agcttatcct ctttctaaga aagacttggt
     4381 tggacgtcgt tggattaact acttcttgat tgtgactatg ttctttggtg gtggtttagt
     4441 cccaacttac ttgctcgtaa aagaattggg aatgctcaat actccatggg ctatcattgt
     4501 tccaggtgct gtcaatgttt ggaatattat tcttgctagg gcctatttcc aaggattgcc
     4561 tgaagaatta gttgaagctg ctgtcattga tggtgcaaat gatttacaga ttttcttcaa
     4621 aatcatgctt cctcttgcaa aaccaattat gtttgttctc ttcctctatg cttttgtagg
     4681 acagtggaac tcatactttg atgcaatgat ttatatcaag gatccaaact tggaaccatt
     4741 gcaacttgta cttcgtaaaa ttctcattca gagccaacca ggtcaagaca tgattggagc
     4801 acaagcggct atgaatgaaa tgaaacgttt agctgaattg attaaatacg caactattgt
     4861 catttccagc ttgccattga ttgttatgta tccattcttc caaaaatact ttgataaagg
     4921 aattatggct ggttcactta aaggataaaa aaagaaaaaa taaaaggagt tttctcatga
     4981 aattcaaaac attctcaaaa tcagcagttt tgttgacagc tagtttagca gtacttgcag
     5041 cctgtggctc aaaaaataca gcttcaagtc cagattataa gttggaaggt gtaacattcc
     5101 cgcttcaaga aaagaaaaca ttgaagttta tgacagccag ttcaccgtta tctcctaaag
     5161 acccaaatga aaagttaatt ttacaacgtt tggagaagga aactggcgtt catattgact
     5221 ggaccaacta ccaatccgac tttgcagaaa aacgtaactt ggatatttct agtggtgatt
     5281 taccagatgc tatccacaac gacggagctt cagatgtgga cttgatgaac tgggctaaaa
     5341 aaggtgttat tattccagtt gaagatttga ttgataaata catgccaaat cttaagaaaa
     5401 ttttggatga gaaaccagag tacaaggcct tgatgacagc acctgatggg cacatttact
     5461 cattcccatg gattgaagag cttggagatg gtaaagagtc tattcacagc gtcaacgata
     5521 tggcttggat taacaaagat tggcttaaga aacttggtct tgaaatgcca aaaactactg
     5581 atgatttgat taaagtccta gaagctttca aaaacgggga tccaaatgga aatggagagg
     5641 ctgatgaaat tccatttaca tttattagtg gtaacggaaa cgaagatttt aaattcctat
     5701 ttgctgcatt tgatataggg gataacgatg atcatttagt agtaggaaat gatggcaaag
     5761 ttgacttcac agcagataac gataactata aagaaggtgt caaatttatc cgtcaattgc
     5821 aagaaaaagg cttgattgat aaagaagctt tcgaacatga ttggaatagt tacattgcta
     5881 aaggtcatga tcagaaattt ggtgtttact ttacatggga taagaataat gttactggaa
     5941 gtaacgaaag ttatgatgtt ttaccagtac ttgctggacc aagtggtcaa aaacacgtag
     6001 ctcgtacaaa cggtatggga tttgcacgtg acaagatggt tattaccagt gtaaacaaaa
     6061 acctagaatt gacagctaaa tggattgatg cacaatacgc tccactccaa tctgtgcaaa
     6121 ataactgggg aacttatgga gatgacaaac aacaaaacat ctttgaattg gatcaagcgt
     6181 caaatagtct aaaacactta ccactaaacg gaactgcacc agcagaactt cgtcaaaaga
     6241 ctgaagtagg aggaccacta gctattctag attcatacta tggtaaagtg acaaccatgc
     6301 cagatgatgc caaatggcgt ttggatctta tcaaagaata ttatgttcct tacatgagca
     6361 atgacaataa ctatccaaga gtctttatga cacaggaaga tttggacaag attgcccata
     6421 tcgaggcaga tatgaatgac tatatctacc gtaaacgtgc tgaatggatt gtaaatggca
     6481 atattgatac tgagtgggat gattacaaga aagaacttga aaaatacgga ctttctgatt
     6541 acctcgctat taaacaaaaa tactacgacc aataccaagc aaacaaaaac tagaggttga
     6601 ttatgggaga taagaaatac acagtagaaa aagccaatcg ttttatagca gaaaataaac
     6661 atctcgttaa tactcaatat aagcctgaag aacatttttc agctgagatt ggttggatca
     6721 atgatccaaa tggatttgtc tattttcgtg gagaatacca tctcttttat caattctatc
     6781 catatgatag tgtttgggga cctatgcact ggggacatgc taaaagtaag gacttggtga
     6841 cttgggagca cttgccagtg gcacttgctc ctgaccaaga ttatgaccga aatggttgtt
     6901 tctcaggctc tgccattgtc aaggatgatc gcctctggct catgtacact gggcatatcg
     6961 aagaaaaaac cggtgtccgc caagtgcaaa atatggcatt ttcagatgac gggattcact
     7021 ttgaaaagat ttcccaaaat ccagttgtaa ctggaacaga cttgccagat gagttgattg
     7081 ctgctgattt ccgtgatcca aaactctttg aaaaagatgg acgctattac tccgtagtag
     7141 ctgtcaaaca catggataat gtgggctgta tcgttctact agggtccgat aacctagtag
     7201 aatggcagtt cgaatccatc tttttaaaag ggggagaaca ccaaggcttt atgtgggaat
     7261 gcccagatta cttcgagtta gatgggaaag attgccttat tatgtcaccc atgcgttatc
     7321 agcgtgaggg agactcatat cataacatca actcatcgct tttgttcacg ggtaaggtag
     7381 attggagaga aaaacgtttt atcccagaat cagttcaaga aattgatcat ggccaagact
     7441 tctatgcgcc tcaaacattg ttggacgatc aaaatcgtcg tatcctgatt gcttggatgc
     7501 agacatgggg gcgtaccctt ccaacccatg accaagaaca caaatgggca tgtgccatga
     7561 ctttacctag aattctaaga ttggaagatg gcaaactaag acaattccct gttaaaaaag
     7621 gccaatatca aatccaaata gataaagatt gtcattacca cttaggaaat gatatagatt
     7681 atcttgaatt tggttatgac agtaatgcgc agcaagttta cattgatcgt agccatctta
     7741 ttcaaaaaat tctaggtgaa gaagaacagg acactagtcg acggtatgta gatattgaag
     7801 ctaaagaatt ggaagttgtt ctagataaaa attccatcga gatttttgtc aatcaaggtg
     7861 aagcaagctt gactgcaact tattacttaa cggtgccagc tgagctatca cgaattgatt
     7921 aaaaattaag ttatttctcc taaagaaaaa gttctctttc taaaatagtg gaaagaggac
     7981 tttttgtgtt ttgggtatat aagcttagtt tatggtattt gtaaaattgg tgttggatta
     8041 tgatttaagc tagttttcta aagaatttga aaaaaatttt atttaagcaa aaaaagccct
     8101 atattataag acttttcctg ttgtatttag atgcccccta cagggatcga acctgtgacc
     8161 cacggattaa gagtccgctg ctctgccagc tgagctaagg aggcaaagaa aaaagctgta
     8221 ttggtgccga aacttcacgg tttgtattga acccgcgcaa ttaagcaggt gggcaactcg
     8281 ctctaactga agctgtttcc gtgtgagacg gcctacatgc tgttagaaga cttttgtttc
     8341 cctaataata caaaaaatag tcggtcaaca cttaagtgtg aagtcgtaca ccacagcgtt
     8401 tctatactta tatgatacca ctttttcaaa aaaaatcaag aggaaagtgc aattttttga
     8461 aaaggatttc agatttttcg caaacggtcg atagcttcct ttctttgagc caaagcccgt
     8521 tcatatttac cagtatcttc tgcttggaaa tagtgatgat tacgaatttt ttctggcaga
     8581 tagtcttgct tgacccaatt tccaggatag ttgtgtggat agagatagtc ttgggcattc
     8641 cccagttcct tgcttccact gtagtgccca tcacgtaggt gtcgcggaat aggcaagtgc
     8701 cctgatgttt tgaggtcagt aagtgcctta tccatagcta cataggctga gttggatttt
     8761 ggagaaaggg ccaaatcaat cacgacattg gcaatgagaa tgcgggcttc tgggaaccca
     8821 atcttctggg cagcatccag agcagtcacg gtatgaatct gggcctcagg attggctaag
     8881 ccgatatctt cataggcgat aacagtcaag cgacgagcga gactaggcag atccccagcc
     8941 tcaatcaagc gggcagcata gtggagactg gcatccacat ctgagccacg gatagacttt
     9001 tgcagggcag atagaacatc atagtgaccg tctccatcct tgtccatagt gatgtagctt
     9061 ctctgaagac tattttccat gatgtctaag gtgatgtggc gaatgccctc gtcattctca
     9121 ggggtagaga gaacagccaa gtccagtgag ttaaaggcag agcgaaggtc tccgtttgta
     9181 gaggttgcga tgaaatccag cgcatcctca tctagttcta ttggaaaatc aaaaccacgt
     9241 tcagggttac ttagagctat ctgcagggcc tctttgacgt cttggttaga cagaggttcc
     9301 aactcaaaaa tttgaacacg gctacgaatg gcaggagtga cggaaaagaa aggattttca
     9361 gttgttgctc caatcatgat gaccagtcca ctttccaaga gaggcaagag gaagtcttgc
     9421 ttggtcttat ctagtcgatg aatttcatct agcaatagga cgagaccacc agaaaattta
     9481 gcttcttccg agatttcttg cagtcgcttt ttactatcaa ctgtcgcatt gaaagttcga
     9541 aaggcatact tggtcgttcc agcgatggca gaggcaatac tggttttgcc gattcccgga
     9601 gggccatata gaatcatgga ggacaggcgg ttggcttcca ccatgcggcg gatgattttt
     9661 ccaggtccga ccagatgctc ctgaccgatg acctggtcga tggttttagg gcgcatgcga
     9721 agcgcgagat tgtctggcat agtagtcctt tctagtgtgg atttgagtag aatgactcat
     9781 ctactatatc ttactatgtc cattctagcc tattagttgt gatatttcaa tggttttgta
     9841 ataatcaggg agtgagatag aatctttttt actatttaat ttaatgagga gaggtatcag
     9901 catgagagat ttgattttcc ttaaagctca aaataggata gttgagccta aagaagtgga
     9961 agtgctgact tgagaaataa tattgctaaa tgtcattgta tgaactataa tgaaaagaga
    10021 ggtgataagc aatggaaatg atggaccaag tcaggaaatt ttgattttta caaaacaaat
    10081 tcgtcattgg attcttagtg atcaagttat ttcagggaaa agaaaacttt tcttccggga
    10141 agatactcca aaagagattt tagatttgta cgaaaacatt aaatctaaac ttgattttgc
    10201 ttaccaagaa gtttattcta ataatgggtt gaaaaaatat gaaaaataga ataattgatg
    10261 tttttgaagt agtaaatcgc atccttgtaa taactgttga aaatcctgat ttcgaagact
    10321 tgagagttaa tcatactcaa tgaaaatcaa agagcaaact aggaaactag ccgcaggctg
    10381 tacttgagta cggtaaggcg acgttgacgt ggtttgaatt tgattttcga agagtatcag
    10441 tttgtaaaaa ttggagataa aaaatataga gtacgcagtg ttcctatgat tcattcaact
    10501 ccgcctcaat ctgtcttaga tcgagatact tttacaattg actatacaga tgatgaattg
    10561 ctcgataaag aagcagtttt tactactcat tagaaaaata ggtctgaata aattggcttc
    10621 ccttagaacc acatctaggg gcttttatgt ataatagaat aataagtatc actcctttac
    10681 aatacgtgta acacgtgtta taatggtgtt gtcaggaggt aaaagcgcta tgcctatgac
    10741 acaaaaagag atggttaaac tccttacggc ccatggttgg ataaagacta gaggcggtaa
    10801 aggctcccat attaaaatgg agaagcaagg ggaaagactt atcacaatcc ctcatggtga
    10861 gctgaataag tacactgaaa gagggataag aaagcaagct gggttgtaaa attcagcccc
    10921 tgttttttga tatggaggta gtgaaatgtt agttacgtat ccagctttat tttattatga
    10981 cgacacagac ggaacagaag cgacttattt tgtccatttc ccagattttg aatactcagc
    11041 tacacaagga gaggggattt ctgaggcttt ggctatgggg tcggagtggc tagggataac
    11101 tgttgcagat ttgatagaga gtgatggaga gttacctcag ccatcagata tcaatagctt
    11161 gtctttaatt gataatgatc cttttaaaga tgatgaagat ttcgtgtcaa cctatgacct
    11221 tgataaatct tttatttcta tggtatctgt tgatgtatca gaatacctag gaagtcagga
    11281 acccattaaa aagactttga ctataccaaa atgggcagat aagttgggac gagaaatggg
    11341 acttaacttt tctcagactt tgacagacgc tattgcagat aagaaagttc aagcctaaga
    11401 ttaagcgtgg tatcgtggta atagtcaata aaaaagcacg tccacttgtg ctagttactc
    11461 gcctattgat tttatagatt tattagccct ttcgagggct ttttatattg atttttatga
    11521 gaaatgaaga aatcagactt ttaagaaaat cactgatacc aagggtttaa atgaggtaat
    11581 atggtataat taggacataa aataattttg tggtaagatg gtagtatcta ttttagcata
    11641 tttccgagca atcggggcga ttaaagagtc gcatagaaag aggacaaaat ggcaacatac
    11701 ggatttttag atgttttaga ggaagagttg gacaagaact ttccctttga ctttgagatt
    11761 agctgggaca aacgcaacta tgcggtagaa gtgagttttc tattggaagc gcaaaatgct
    11821 gcaggtgtgg agatggtgga tgaagacgga gaggtttcat cagatgacat tctttttgag
    11881 gaagcggtcc ttttctacaa tcctgccaag tcaacagtca atgaggaaga ctatttgact
    11941 gttattcctt acctgcctaa aaaaggattt tcccgtgaat ttttagctta ttttgcgctt
    12001 ttccttaaag atactgctga ggttgggcta gatgccctca tggacttttt ggaagatcca
    12061 gaagcagagg aatttgttat ggaatggaat caagaagtct ttgaagaagg aaaagttggc
    12121 ttggaagagg gagaatttta cccttatcca aaatactagg agttggttgg aggtgttatg
    12181 aagaaaattg ggacttattt ggtttatgtg ctagctgttg tctttattat gctagctttt
    12241 gcttgtggaa caatcgcatt tgcagagttg gggtattccg cagttttagc ctttactttt
    12301 ggttatgcct ttgctcttct aagcatgtat ttaatcttta ttcttcatga gctgggtcat
    12361 gctttttgtg gctacttgac aggctatcgg ctggtggctt ttggattagg acattttatt
    12421 ttgaccaaaa agtcaggcag gtttcatctt agtagaacag ccattctgaa aaatgttggt
    12481 gctcaataca ttggtttaaa agaggatgaa agcgatcaaa gaatcatcct gatgctttca
    12541 ggaggcttga tggttcatct cggcttgata ttattggcga tattgtttgg atttttgaca
    12601 agaagctggt attttgcagg gacttggatt tttcttaatt tatctttctt cctaaataac
    12661 attttaccag tcgacatcac cgatggagca aaaatttggg aattactaca acaccctgaa
    12721 aataccaaat acgcctacct ggtattgaga cattctgccc agaccttgct ggctcctcaa
    12781 gaatatgatt tgaaagactt tgttcaagca gttcctgagg atgcacgagg gagttttgcg
    12841 gatggtgtat taggtatgca aggtgaagtt tccattttgg aagggaagga agaagtagct
    12901 aaacagcagt ttcaagcatt acttgagagg acaactactc cgatgatgca gacagttgcc
    12961 caactatccc tgcttcatat cgccttgttg gaaggagatt ttgagcaagc ggagcaatat
    13021 gccagtattc gacaggtcaa atcgtttctg tctctcaaac tgtccaatct tcaagtgata
    13081 caagcctggt atcaatttaa ggtaaggaaa gatgtggttc aaactcacaa ggctatgaag
    13141 attgctagac agaaaatgga tagtagtcga atgttgaggg acgagaaacg ctattatgaa
    13201 aacttgttag cagagctgga aaaggaaatg ttagaaggaa ctgaagatgg aactagaaat
    13261 ttctgatttc ccaggctgta agattgcttt gttttgtggg gataagcttt tgactatctt
    13321 acgcgatgat aaggcaagca ttccctgggc caatatgtgg gaactgccag gtgggggaaa
    13381 gagtgtcagg gaaaatctga tatagttttg cattaaaaga atatcctttc aaggttattc
    13441 ttttttaatt ttgtcccaaa ataattgact ttgtcccgaa aatatagtat tatttgtata
    13501 aggaggaatg aatcatgaaa aaatcagatg ttcttgattt aataaagtat cattatgagg
    13561 gcagagagac agaatttaga aatcaatcca tagcaattgc tcggaacttc aataaacatg
    13621 gtgatacaca aatagcacaa tatattatgg ggttaatgtc tcaaagtgat agattcatgc
    13681 cacaaataga aaatcctagt gagtatttga ctcctgctaa actagatatt ggtcctctcc
    13741 cattgcctct ttcaattatg aatgatttaa aaggaataat aaacgctgtc aatcatcata
    13801 ttggaataaa taaattttta tttgtgggat ctccaggtac tggaaaaact gaaagtgtaa
    13861 agcaggtggc tagacttatt ggcaaggaat tacttgtagt agatttcagt cacttagtag
    13921 atagtaagct agggcaaaca gtcaaaaact tagcaactct ttttaatgaa atcaataatc
    13981 ttcctttcaa gcaaaattat atcatcctat ttgatgaaat tgattccata gtgttggata
    14041 gggttaatca gaatgattta agagaaatgg gacgagtgac ttctgccttt ttaaaggagt
    14101 tggataggct gtcaccagaa attgtattaa ttgcaacaac aaatcttttt gaaaatcttg
    14161 ataaagcagt tacgagaaga ttcgatgcca taattgactt tgaccgttat actgatgaag
    14221 ataaagtaga agtagctact attattttaa atgagttatt aaagcaattt aagaatgtag
    14281 ctagagattt aaaattattt aaaaaaatta tcaatagtgc caatgtaata ccgaatcctg
    14341 gtgatttgag aaactcaata agaacgtcat tggcatttag tgacccatca gatccgcatg
    14401 attaccaaaa acgcctgcta agaagtttgc ataatggtag aaatttatct atttctaaat
    14461 tatcgaagct aggttttact gttagagaaa ttgagatttt gacaggtatt tctaagagta
    14521 gtgtatcacg agagttaagc gaggattaaa atgaatacat tattgacatt acgaggtaaa
    14581 agttttacac aaaaatcaag aaataatggt atgggaccaa taactatacc caaaaaaaca
    14641 ataattacat tggaacattt gaagtatctt catttttcat tagaagagac gaaaacatat
    14701 tgggagaaaa ataacattat cgatggtatt ttgatcagta tttactataa tcgaattgtt
    14761 gccaaaagta accgtattaa tggctatttc aatgtaggag gagggaatcc attccctaat
    14821 gatactattg tgggagcaaa attcaatgat gagaagacaa aacatattgt tactcattat
    14881 atttctagag atgctcttaa taaaacaata accgttttaa gtaagataat tgaagttttt
    14941 gaggaacatt ttgatagagc gataacatgt gagatgtttt ctgattcatc aacgtttgct
    15001 tctataaatt tttcggagta tggtatttca aaaagcaaat ttcaacagta tttgagagat
    15061 tcttgcttta ttgagaattt tggagttgag cacactactg tttctgatat tcaaaattct
    15121 atcgtgacat tttatgatgt ccatacagac atttttagat tactgaataa attaaatatt
    15181 gatatttcag aagctaatat catgaatcag accacggtct tgcttgatga aaaaaatatt
    15241 gaattgctac tatcaaaagc gccctatctt gtctccatga ttgtggaaga tttttctaag
    15301 ttatctgtag atgatttttc tttagataat aatgatttaa aaataaatct tccatctcca
    15361 atgaacgaac cagttgttgg cgttattgat accttatttg acaaaagagt ttactttaat
    15421 gagtgggtag aatatcatga ttttgtctca cctgatatta gcaaagatag ccaagattac
    15481 aagcatggga cagctgtgac ttctttaatc gttgatggag ccaatttgaa ccctaatctg
    15541 gatgatggtt gtggaaattt tagagtgagg cattttggtg tgtcactaca aagtggattt
    15601 aattcattta caatcataaa acagataaaa gagattgttt ctcagaatgc tgatattaag
    15661 gtttggaatc tttctttagg gtccaatgat gaaataagag aaaattttat ctctgcagag
    15721 ggagcattat tagacgaaat tcaatttgag aatgatgtaa tttttatcat agctgggaca
    15781 aatgcttcag taataaatgg gaaacgcaaa agaataggtg ctcctgctga ttcacttaat
    15841 tctataatag taaattctgt tgattttaat aatcaatcag tgtcatattc acgagagggt
    15901 attgttttat cattctttgt taaaccagat gtgtcatatt atggaggagg aaatggtgac
    15961 tttataaatg tttgtgaacc tctaggatta ggtcgtgtag ctggaacaag ttttgcggca
    16021 ccttttattg caaggaaaat ggcctatctc attcatatta tgggacttag ccgagaagaa
    16081 gcgaaggctt tgctaattga tgcagcaata ccctggaatg ataagaaaac attcactgat
    16141 ttatctttga taggaaatgg tattgttcca ataaaaatgg atgatatttt atctacacct
    16201 gatgatgaaa ttaaatttat tgtgtcagat atctctaggg cttatgatac ctataattat
    16261 gattttccag tacctatttc tagtgagagt tatccatatg tagctaaagc aacaatgtgt
    16321 tatttcccta actgctcaag aaaacaaggg gttgattata caaatactga gatgcagctt
    16381 acttttggta ggttaaagtc agacggtatc aaatcgataa ataaagacaa ccagcatgcc
    16441 gaagataccc caggatatgt gagagaaaac gctgctagaa atatatttag gaaatgggat
    16501 aatgtcaagc atattggaga gtcgtttact tctcgaaaga gagctaaagc aattttaaat
    16561 ccatctaatc ctcagtgggg gatgagtatt aaaacaatcg aacgtttgaa aagcggtgat
    16621 ggacaaggag tacgttttgg tgtagtagtt acattaaaag aattaaatgg ggttaatcgt
    16681 attgaagatt ttattcagca agctgaatta cgcggttggc tagttaatag attgcaagta
    16741 gaagctcaag tagacctctt taatagttta aatgaagaaa ttgaatttga atagtggata
    16801 ttttatcctt attttagatc ttaggaacac aagagggcaa agatatgaat attacttata
    16861 tagttggaaa tggtttggat ttgcaatatg gtttgaaaac aagatatagg gatttctacg
    16921 aattccaaaa taaggtttat ataagtagga cagagaacga ggaaaaatat tcaaatttca
    16981 tttatgagtc tctattttct gataaagtaa atgattatga aaattggtca gattttgaat
    17041 tgtcaattgg taaattgaca aaagataacg acctcatctc ctcaagtata gaaataaagg
    17101 agaaatttat agatgatttt agtgaagtag ttgatgattt aagagaatat ctacgcatac
    17161 aacaagaaaa aaatcttgag aaaggtaatg caattgactt tataagcact ctagatgata
    17221 tgaggacctc tctccctgta attaatcaac ctgctatcga taaaaaatac aatgagaatc
    17281 cacatcagga cgacattgta aatatagtaa cacttaatta tacacatgta atcgataaat
    17341 tatataatgg gtcagcaaaa tcattcagga atcaattacg agctaatctt tataattttt
    17401 atattgagcc accaattcat gcacatggga cggtggatgt ctgcacggtt ttaggggtta
    17461 gtgatgaaat acaaatttca aatagtttag aagaacaaaa ggaatcccta ataaaaagtt
    17521 tagttttaaa aaactataga gaaaatatgg atgtaaagaa tagtgatatt ataaaaaatt
    17581 ctgacatcat tattctctat ggggtttctt tgggagaaac tgataggtat atctggagtc
    17641 agattgctga acgatcaatc agcggttctg ttcctgtcat aatttaccac tatgtacctc
    17701 attttgatcc ggggaatccc attagagcaa aacgcctata tagaaatgta gaagataaat
    17761 tcatacagaa tagtggtata gacttagagt tagagaaaaa attaagagac aaccttattg
    17821 tcgttattgg taagactatt tttgatctaa tagagaggta attttaaaaa acaaaatgga
    17881 aacatggcaa gagttaaaag ttacagtgaa gcgtgagggg gaggagttgg tttccaatct
    17941 cttgattgag ctgggagcgc aaggtgttgc gattgaagac agtctggact atgtgggaaa
    18001 tgttgaccgc tttggcgaga ttttcccaga ggtggagcag caagaagaaa tcgtagtgac
    18061 cgcctactac cctgacacgg tggatgtgac agtggttgag gcggatttgc aggctcgtct
    18121 agcagaattg acagatttta tggatttggg agagttaaaa ataggtacga ctgccttggc
    18181 tgaggaagac tgggcagaca actggaagaa atactatgag ccagctcgta tcactcatga
    18241 tttgaccatt gttccctctt ggacagacta tgaggcgact gcgggagaaa aaattatcaa
    18301 gctggatcct ggcatggctt ttggtactgg aacccaccca actaccaaga tgagcctttt
    18361 tgccttggaa caggttcttc gtggtggcga aacggtgcta gatgtgggga ctggttcagg
    18421 ggttctctct attgccagct cgcttctggg ggctaaagaa attttcgcct atgacctgga
    18481 tgatgtggcg gttcgtgtgg ctcaggaaaa tattgagctc aaccctggca tggaaaatat
    18541 ccatgtagcg gctggagatt tgcttaaggg tgtggaaatt gaggcagatg tgattgtggc
    18601 taatatcttg gcggatatcc tcattcatct aatagacgat gcctatcgtt tggtcaagga
    18661 cgaaggctac ctgatcatga gtggcattat caaggataag tgggacatgg tgcgtgagtc
    18721 ggctgaatcg gctggatttt tcctcgaaac ccacatgatt caaggggagt ggaatgcctg
    18781 tgtctttaag aagaccaagg atatttcagg ggtgattgga ggctagcatg cagcagtatt
    18841 ttgtaaaagg cagtgctatc tctcctgtca ctatcgagga caaggaaatc agtaagcata
    18901 tgtttcaggt tatgcgcttg aaagaagagg atgaggttac cttagtcttt gatgatggca
    18961 tcaagcgctt ggcgcgcgtg ctggatatgg aaaatcgtca gtttgagttg gtccaagaat
    19021 taaatgacaa tgtggaacta ccagtccaag tgaccatcgc atctggattt cccaagggag
    19081 acaagctgga gttcatcgct caaaaagtaa ccgaactggg tgctagccaa atctgggcct
    19141 ttcctgcaga ctggtcagtt gccaagtggg atggcaagaa attgggtaaa aaagttgaaa
    19201 aactagaaaa aattgccctt ggagcagccg agcaaagcaa gcgtaatatt gtaccaagta
    19261 ttaaactttt cgagaaaaaa gcagattttc tagctcagct ggaccagttt gactctatca
    19321 tagtagccta tgaagaatca gctaaagaag gagaagccgc tgcgcttctg caagcagtca
    19381 ctggtcttga aacaggagcc aaactgctct ttatctttgg tccagaaggt ggtctctcac
    19441 ctgcagaaat cgaaagtttt gaagctaaag gagcagtttt ggcaggccta ggtcctcgta
    19501 ttttgcgagc agaaacagca ccgctttacg ccttatcagc ccttagtgtt ttagtagaat
    19561 tagagaaata agaggaagaa aatggaacaa aaacaccgtt cagaatttcc agagaaggaa
    19621 ctctgggact taacagccct ataccaagac cgtgaggatt tcttgcgtgc aatcgagaaa
    19681 gctcgtgaag acatcaacca atttagccgt gattacaagg gcaatcttca cacttttgag
    19741 gatttcgaga aggcctttgc ggaattggaa cagatctaca ttcagatgag ccatattggc
    19801 aactatgctt ttatgcctca gacgacggac tatagcaatg acgaatttgc caatattgcc
    19861 caagctggga tggaatttga aacagatgcc agcgtagcct tgaccttctt tgacgatgcc
    19921 ttggtggtag cagacgagga agtcttggac cgtttgggtg aattgcctca cttgacggca
    19981 gctattcgtc aggccaaaat caaaaaagcc cactatctag gggctgatgt ggagaaggcc
    20041 ttgaccaatc tcggtgaagt tttctatagt ccgcaggaca tttatactaa gatgcgagct
    20101 ggggattttg aaatggctga ctttgaagcc catggcaaga cctataaaaa cagctttgtc
    20161 acctatgaga atttctacca aaatcacgag gatgctgagg ttcgtgagaa atccttccgt
    20221 tccttctcag agggacttcg taagcaccaa aatacggctg cagcagccta tctggctcag
    20281 gtcaagtctg aaaaactctt ggctgatatg aagggatacg actctgtctt tgattatctt
    20341 ctagctgaac aagaagtgga ccgtgtcatg tttgaccgcc agattgacct catcatgaag
    20401 gactttgcac cagtcgctca gagatacctc aagcatgttg ccaaggtaaa tggtcttgaa
    20461 aagatgacct ttgcagattg gaaattggac ttggacagcg ccctgaatcc tgaagtgact
    20521 attgacgatg cctatgattt ggtcatgaag tcggtagaac ctttggggca agaatattgt
    20581 caggaagttg ctcgttacca agaagagcgc tgggtggact ttgctgctaa cagtggcaag
    20641 gattccggtg gttatgcggc ggacccatat cgcgtacacc cttatgtact catgagctgg
    20701 acaggccgtt tgagcgatgt ctataccttg attcatgaaa tcgggcattc tggtcaattc
    20761 atcttttcag acaatcatca aagctatttc aacgcccaca tgtcgaccta ttatgttgaa
    20821 gcaccgtcga ccttcaatga attgctactc agtgattact tagagaacca gtctaatgac
    20881 ccacgtcaaa aacgcttcgc tctggctcat cgcttgacag acacctactt ccataatttc
    20941 atcacccacc tcttggaagc cgccttccag cgtaaggtgt atacattgat tgaagaaggg
    21001 gagacctttg gagcaagcaa gctcaacagc attatgaagg aagttttgac agatttttgg
    21061 ggcgatgcca ttgaaatcga cgacgatgca gctttgactt ggatgcgcca agctcactac
    21121 tatatgggct tgtatagtta cacttactca gcaggactag ttatctcgac tgctggttac
    21181 cttcatctta aaaactcaga aactggagct gaagactggc tcaatctcct caaatcaggt
    21241 ggtagcaaga caccacttga gtcagccatg attatcggtg cggatatttc aacagacaaa
    21301 ccactccgtg ataccatcca attcttgtct gacacagttg accagattat cgcctacagt
    21361 gctgagttgg gggagtaagg ggatagaaaa attttttaga atgatgttta tgggcttgtt
    21421 aagcgtcatt ctatttgtct tagttgtagc tattttcaaa aatgtcgttg aaggtcgtga
    21481 tgttaaattt gaacttactg tagaactggt attgatagtt atttacgtca ttttatatca
    21541 gattgtattt aattgagaat tcaatattga gtcatttaag actgcctttt tgaacagttg
    21601 ctagaaatgt agaggtattg accatgtatc aagatttact aagaaaaata gcagaagaaa
    21661 aaccaaatta taaccaggaa gaaatccagt ggttgtttga tcatttggga aatccttctc
    21721 cagaaattcg tgatgacctt tcaaatcaag gcttgcacta tctttcaaaa gaaaaggata
    21781 caacaggttt ctcaagtcag tatggttggg ttcacgcttt tgcacatgga gccgatttac
    21841 tgacagaggt ggtttgtcat ccagactttc ctaaaaacag agttcatgaa gtatttgata
    21901 tacttggcca actatttaaa agaatgtcga ttcgctttac agatgatgag gattggcgtt
    21961 tagcaagagt gatctatgaa cctattttat aagggaagtt ggagcaagaa caagtagctt
    22021 cttggataaa aactgttgat tttccgatag aagaaaggga ggatttttac aaattttcca
    22081 acttcagatc ctgtctggtg gaagtctatg tccaacttga ccagagaaat agtttacaag
    22141 atgagttgaa agaagctatc cagtcttttc aatactagag attagctaat agttctatga
    22201 ttttcaaaaa atttccaatc aattttcttg aaaccctttc ctacttttga tagactagta
    22261 tctagttttt gaaaaaagga gaaagaaaat gaaaaaattt gttgctgagt taatcggtac
    22321 gttcatgctt gtgttcgtcg ggacaggagc tgttgttttt ggaaatggtc ttgatggcct
    22381 tggttacctt ggaatcgcct ttgcctttgg tttggcaatc gtggtggcag cctactcaat
    22441 cggaactgtt tcaggtgctc acttgaaccc ggctgtttcg attgctatgt ttgtaaacaa
    22501 acgtttgtca tcttcagaac ttgtaaacta catccttggt caggttgttg gagctttcat
    22561 cgcttctggc gctgtcttct tcctcttggc taactcaggt atgtcaactg ctagtcttgg
    22621 tgaaaatgcc ttggcaaacg gtgtcactgt ctttggtggt ttcttgtttg aagtcatcgc
    22681 aactttcttg tttgtattgg ttatcatgac tgtgacttca gaaagcaagg gcaatggcgc
    22741 gattgctggt ttggtaatcg gtttgtcatt gatggcgatg attcttgtcg gattgaagat
    22801 tactggactt tcagtaaacc cagctcgtag cttggcacca gctgtcttgg taggcggcgc
    22861 agcccttcaa caagtttgga ttttcatcct tgcaccaatc gctggtggag ttcttgcagc
    22921 ccttgttgca aaaaatttcc ttggaacaga agaataattg aaactcaaaa agccttgctc
    22981 ctcatcttga ggaacagggc tttttcgtat gatactcttc gaaaatctct tcaaaccacg
    23041 tcagcttcac cttgtcgtat agatgttact gacttcgtca gttctatctg caacttcaaa
    23101 acagtgtttt aagctgactt cgtcagtttc atctacaacc tcaaaacagt gttttaagct
    23161 gacttcgtca gtttcatcta caacctcaaa acagtgtttt aagctgactt cgtcagttct
    23221 atctgcaacc tcaaaacagt gttttaagct gacttcgtca gttctatctg caacctcaaa
    23281 acagtgtttt aagctgactt catcagttct atctgcaacc tcaaaacagt gttttaagct
    23341 gacttcgtca gtcttatcta taacctcaaa cactgctttg agcaacctgc ggctaacttc
    23401 ctagtttgct ctttgatttt cattgagtat gagtttagcg gttgtcaatt ttctctggat
    23461 aaaggtcgtg ttggaagagg cgttgttctg ccaagccctc atacttagtt ccttgcttac
    23521 cgtagttata gtaggggtcg attgaaatgc caccgcgcgg agtgaatttt ccccagactt
    23581 ctaaatagcg agggtctagc aagttgacca agtctttccc gatggtgttg atacagtttt
    23641 cgtggaaatc tccgtggttt cggtagctaa atagatatag tttgagggat tttgactcga
    23701 cacagagctt gtcaggaatg taggaaatat gaatcgtcgc aaagtctggt tgagcagtga
    23761 tttgtcccag cagagacata tcgaggatat ggtgacgaat gccctgttcc ttggcgattt
    23821 ctctagcaat ttgaatttcg aggtgatgat gttggccgta ggcaaaggtg acagcttcga
    23881 ctgtttcata gtgttgcatg gcccagaaaa ggcaggttgt tgaatcttga ccaccactaa
    23941 agacgaccaa ggctgattga cgtttcacag tactccttcc aaaatgggaa atgttcagag
    24001 cacgcaaaaa gctcccatta gggaactaaa aaataccaaa tcgagttttt ttagcgatgg
    24061 cataccccaa acatcgtaat attctactta tatagtaaaa tgaaataaga acaggacaaa
    24121 tcgatcagga cagtcaaatc gatttctaac aatgttttag aagtagaggt gtactattct
    24181 agtttcaatc tactatagtc tagcatattt tttgaaaaat ggcaaagggc aagaaaaaag
    24241 agaccaaaga aagtacttgg tctctcgttt gattagctca attcagcaat gatggccttg
    24301 atttgttctg ctgtgtgaac acctgcaact tgtttgacaa cttggccgtc ttttttgaag
    24361 agaagagttg gaatagacat gattccaaaa gcacgagctg tgtttggatt ttcatcaacg
    24421 tccattttaa cgattttcaa gacatcttct gaaagttctt cagacaattt gtccaagatt
    24481 ggaccttgca tacgacatgg accacaccaa gttgcccaga agtctactaa gaccaaaccg
    24541 tcttttgttt cttgttcgaa tgttgcatct gtaattgctt ttgccattgt atttctcctt
    24601 tttttagtta tattggctta aatcttgttt catgagatag aagaagatat ctccataagt
    24661 cccatggtag tccaaattat gacccttgta agttaatttt tggacagggt agtagtctgc
    24721 gacgccgata aggcaagctt gttgcgaacg ttcaaagtct tcataagact cgaaagtcac
    24781 agttctttcg ttcttgctgg catctaaata ggtaatttca atcatattta aaactccttt
    24841 gtttaatgct aactttattt tactccttat aaaagagaat gtcaagaaaa atgattgcgc
    24901 acgcaacttt ttttaaaatc atcttaaatc aagaaatcca aacctgcttc caagctttct
    24961 tcgacagtct tttgtagcga ggccagtgtc ttttgcccat catttgtcag gcagataaaa
    25021 ctagagcgtc tatcttgatg gcaacacatg cgactgagta gaccgcaatt tttagcttcc
    25081 aagcgagcca ccatcctaga aactgcgctc gggctcagat gaagcttatc tggcaggtca
    25141 atctggcgta gagatttttc ttcagctaag tccagatagt agagcaggta gaactctttc
    25201 aaggtcagac tttgctcgct ctgttgggca atggtctctt ccaagagact ttcaatttct
    25261 ttctgacgcc gattgaagtc aaaccatttt tccaaatagg tcatagtatc tcctttcttt
    25321 ttagagtcat aaatagaaga aagtccatta acgggcagtc tctgcgtcat aagatgattg
    25381 cgcatgcaat aattatacta cttttcaaga atgctggcaa gctctgtttt ttagtggttt
    25441 tcttttttac tgtctatatt tttggtaaaa atcaactttt acttggatga aggttttggc
    25501 ttcacgtagg agttgaagaa gggtggcgcg ggtttcaaat tcttctcttg tcttgggcag
    25561 actgcggttc cggaagactt ccagataacg ttcaatttca tctagcaaat cagaagcagg
    25621 attggtctgg ctcagttgac ctgcaatttt tgaaaagagt tgcgctaaga tcaggctttc
    25681 actggcggca aggtgacaag tgttaatctg ttgggccatg tttctcagga tacgactttg
    25741 tcgctgtctc atctcaaagt agtggatatg gtagtcggtc tggtgaaaga ggtggtcaga
    25801 gtggtccaaa tagaccagtc tgagggcttc tttcaaaagc gtgtctaatt ctgctaccag
    25861 ctgtgctcgg ttgcgtccgt ctcctctgga taaatagtat ttgaagcgct ggaggatatc
    25921 ttttaacttt tcttccacca gcgtgtggta gtgctggatt tcctcttctc gtgaaggcat
    25981 atagagatta acaagcaagg caaatcctgt accaatagca aagagaagga attcattgac
    26041 tagaaggtct ggagaggttg actcttgaac caagagatgg ctaaccaaaa cagtgcttgg
    26101 tgtgatgcca atttcccagc ccatcttgta ggctaaagga acgtagaagg ccagatagag
    26161 gccgagactc cagatatgaa atccgctcaa gtgaaaagct agaacaccga tagccagagc
    26221 tagaagcata gaaaaaagac gattgcgagc cagttttaaa gtacttctac gcgtatcaga
    26281 taggctcaag agagcgataa ttccagccga aactgctgat gaaagattga gaaaataagc
    26341 aagcaggtag gcaagacagg tagctaagat gagcttggtc gtacgttggc taatagacat
    26401 aagaatttcc taataagtta gaataaaagc gtaaaagaca agacatgagc aggcttgcct
    26461 tgatgagtta ttttttacgg gttgctgcgt attcggcaac ggcggtaaag aggacatctg
    26521 tagaagagtt aagggctgtt tcacatgagt cttggatgac accaatcaca aaaccaaccc
    26581 caacaacttg tatggcaata tcgttagaaa taccgaaaag gctacaagca actgggataa
    26641 gaaggaggga acctccggca atacctgaag caccacaggc tgagatagct gctaccacac
    26701 tgaggacaaa ggctgtggca aagtcaacag gaattccaag agtgttaact gcagcaaggg
    26761 tcaaaacgtt aatggtaatc gctactccag ccatattgat agtagaaccg agtgggatag
    26821 aaacagaata ggtatctggg ttgagtccaa ggtcatggca gagtttcatg ttgacaggaa
    26881 tgttagccgc agaactacga gtgaaaaagg ctgtcacacc gctgacacgg aggcagttcc
    26941 aaactagagg gtaaggatta cgtctcataa agaagaaggc aatcaaaggg tgaccacaag
    27001 ggcaacaaaa agcatagtcg ttactaatag aaccaataaa ataccgtagt tggcaaggct
    27061 tccgactccc ttgtcagaaa tggttttaaa aacaagacca aggattccaa atggagccag
    27121 attgatgatc cattcgacaa ttttagaagt cacgtcagcg atagttttta gcaattcttt
    27181 actattttta ctggcttctc tcatagcgat tccaaaaatg actgcccaag ataagattcc
    27241 aatatagtta gcagtaagca gggcgttgac tgggctgtca accagtttga gcaagaggtt
    27301 gctgaggacc tgcccaatcc catctggtgg tgcaatttca gtattggcac tatttagggt
    27361 aatttcaata gggacgatga aacttgctag tacagctaca agagcagcgg cgaaagtccc
    27421 tatcatagga tatacaagaa aacaacagtt ttcatattgc tatcttgtcc cttttgatgt
    27481 tgggaaaggg cattggcaac gagggcaaag actaggatag gagcaacagc ttttagacct
    27541 ccaacgaata aatccccgag tagcccaatc cctgagagat taggaagggt cagtcctagg
    27601 attccccata aagcatacca atcaagatac gcttgacaag gcttgcctta ttccaagcat
    27661 gaatgattct tttcataata atcttctttt tgtgtagtga ttatgattat agtataaatg
    27721 atagacaaaa tcaagaattt tctgtctatt ttttgaatat ttatggagaa tgagactgat
    27781 gaaaatatgg tataatgaaa taaaggagtt ttatatgcaa aaatttattc aggcttatat
    27841 tgaaaagcta gatgtgacaa ccattatcga gaatattcta accaaggtca tttctctttt
    27901 actgcttttg attgtatttt atattgctaa aaaaatgctt cataccatgg tgcagagaat
    27961 tgtcaaacct tctctaaaaa tgtctcgtca tgatgtcgga cgccaaaaaa ccatctcacg
    28021 tttactagaa aatgtgttta attatacgct atatttcttt ttactctact gcattttgtc
    28081 gattttaggt ttgccagttt ctagtttgct ggctggagct ggtattgctg gggtagcgat
    28141 tggtatggga gcccaaggct ttctgtctga tgtcatcaat ggctttttta tcctctttga
    28201 acgtcaactg gatgtgggag atgaggtcgt tctgacaaat ggaccgatta ctgtatcggg
    28261 taaggttgtc agtgtgggaa ttcgtacgac acagcttcgt agcgaggagc aagcccttca
    28321 ctttgtccct aaccgaaata tcacagttgt tagcaatttc tcacgcacag actagacctg
    28381 ttattttaag taatttgtgg tacaatagag ggagtttaat aaggagaaaa gatggtttta
    28441 gaaaagcagt tgggcaatgg ttgtacctgg atagacctag acctaggaaa gttgaataaa
    28501 ctagaagacc tttctgaaat ttacggtttg gacaaggaaa ccattgaata cgcactggat
    28561 agaaacgagc gcgcccacat ggactaccac cgtgaaagtg ggacggttac ctttatctat
    28621 aatgtcctag acgtaaaaaa ggacaaggcc tactatgaga cttttcccat gacctttatc
    28681 gtcgagcatc gtcgcctgat taccattagt aataccaaga acgcctatgt cattggacag
    28741 atgactcgtt atctggagag ccatgacacg ctttcgattt ataagtttct ctttgccagt
    28801 ctggaaatca tcagcaatgc ctactatcct gtcattgagc agatggacaa gagtagggat
    28861 gaggtcaatg accttttgcg ccagcgaact accaagaaaa acctctttgc cctgtctgat
    28921 ttggagactg gtatggttta tctgacggca gctgccaaac aaaatcggat tttgttagag
    28981 catattcaag gtcatgcctt gtatcgtagt tttgatgaga ttgagagaga acagtttgat
    29041 gatgccatga ttgaggctca tcagctggta tccatgacag acctaatctc tcagatttta
    29101 cagcagcttt cagcctctta caacaatatt ctaaacaata atctgaatga caatttgaca
    29161 accttgacta tcatttcagt cttgctagct gttttggcag tcgtgacagg ctttttcgga
    29221 atgaatgttc ccttaccttt aacagatgag ccccatgctt ggctctatat cagtttggct
    29281 agtgcaggtt tgtggattgt tttatccttg ttactaagga aaattgcgaa aaaaagttaa
    29341 gaaaaggagc cagaatggcg attgaaaatt atataccaga ttttgctgtg gaagcagtct
    29401 atgatctgac agtcccaagc ctgcaggcgc agggcatcaa ggctgttttg gtcgatttgg
    29461 ataataccct cattgcttgg aacaaccctg atggaacgcc agagatgaag caatggctac
    29521 atgaccttcg ggacgcgggt attggcatta tcgtagtgtc aaataacacc aaaaaacgcg
    29581 ttcaacgagc agttgagaaa tttgggattg attacgttta ctgggccttg aagcccttca
    29641 catttggtat tgaccgtgct atgaaggaat tccactatga caaaaaggaa gtggtcatgg
    29701 ttggtgacca gctcatgaca gatatacgag cagcccaccg tgcagggatt cggtcaattt
    29761 tagtcaaacc cttggtccaa catgactcaa tcaaaacgca gattaaccga actcgtgagc
    29821 gtcgtgttat gagaaaaatc actgaaaagt acggaccgat tacatataaa aaaggaattt
    29881 aactatggaa gaaattctct gtattggttg tggagcaacc attcagacga cagataaagc
    29941 tggtcttggt tttacccccc agtcggcact tgaaaaaggt ttggagactg gcgaagtcta
    30001 ttgccaacgc tgtttccgtc tccgccacta caatgaaatc acagatgtcc agttgacgaa
    30061 cgatgatttc ctcaagctct tgcacgaggt gggagacagt gatgctttag tggtcaatgt
    30121 cattgatatc tttgatttta atggatctgt catcccaggt ttaccacgtt tcgtctcggg
    30181 caatgatgtc ctcttggtag gaaataaaaa agatatcctt cctaagtcag ttaagtctgg
    30241 taagattagc cagtggctca tgaaacgtgc ccatgaagaa ggtcttcgtc cagtcgatgt
    30301 ggtcctaact tcagcacaaa ataaacatgc cattaaggaa gtcattgaca agattgaaca
    30361 ctaccgtaag ggccgcgatg tctatgtggt cggtgtgacc aacgttggaa aatcaactct
    30421 aatcaatgct attatccaag aaatcacggg tgatcagaat gtcatcacta cttcacgctt
    30481 cccagggaca accttggaca aaatagagat tccgcttgac gacggatctt atatttacga
    30541 tacgccggga attatccacc gccaccagat ggctcactac ttgacggcca aaaacctcaa
    30601 gtatgtcagt cctaaaaagg aaatcaagcc taagacctat cagcttaatc ctgagcaaac
    30661 cctattttta ggtggtttgg gacgctttga ctttatagca ggagaaaagc aaggatttac
    30721 tgctttcttt gataatgaac tcaaactcca tcgtagcaag cttgaaggag ctagtgcttt
    30781 ctacgataag cacctgggaa ctcttctgac accaccaaat agcaaggaaa aagaagattt
    30841 cccaaggcta gtccagcatg tctttaccat taaagataag acagacctag tcatctcagg
    30901 cctaggctgg attcgtgtaa caggcatagc aaaagtcgcc gtctgggcac cagaaggcgt
    30961 cgccgtcgtc atacgaaaag caattattta aaacaaaatc gctgagcgaa caaagtgagc
    31021 tcatatagcg atagttattg ccgtggtgtg attgccaatc tgtagattgg caaggggcac
    31081 aattgagacc aaggctcaat tgtgaggtca ggaaatccat ttttcaaaga tgaaatcttt
    31141 ggaaaattag ttccgaccgt ccctcaccac ctaaaataac tatcaaaaaa caaggaagaa
    31201 aattatgtca ttaacatcaa aacaacgtgc cttcctcaac agccaggcac acaccctcaa
    31261 acctatcatc caaatcggga aaaatggact caacgaccaa atcaaaacca gcgtccgtca
    31321 agctcttgat gcgcgtgaat taatcaaggt tactctctta caaaacacag atgaaaacat
    31381 ccacgaagta gctgaaattt tggaagaaga aatcggtgtg gatacagtcc aaaaaatagg
    31441 acgcatcttg attttgttta aacaatctag caagaaagaa aatcgcaaga tttctaagaa
    31501 agtcaaagaa atctaagacc gaaactccaa ataactgttt ttatagagaa ataaagggga
    31561 ctagcctatg acaatcgaac tattgactcc ctttaccaag gtagagttgg agccagaaat
    31621 caaggagaaa aaacgcaaac aagttgggat tttagggggg aattttaacc ctgttcacaa
    31681 tgcccatctc attgttgcgg atcaagtacg gcaacagttg ggactggatc aagttcttct
    31741 catgcctgaa taccaacctc ctcacgttga taaaaaggaa accatccctg aacaccatcg
    31801 tctcaagatg cttgagttgg caattgaggg gattgacggc ctagtcattg aaaccattga
    31861 gttggagcgc aagggtattt cctacaccta cgacaccatg aaaatcttga cagagcaaca
    31921 tccagatacg gattattact ttatcatcgg cgccgacatg gttgactatc tgcctaagtg
    31981 gtaccgaatt gatgaactgg ttgacatggt tcagtttgtg ggggttcagc gtccacgcta
    32041 caaggcaggg acttcctatc cagttatctg ggtggacgta ccgctcatgg atatctcgtc
    32101 cagcatggtg cgggacttca ttgcccaagg tcggaaaccc aactttctcc tacctcagcc
    32161 agtgctagac tacatcgaga aggaggggct ctactgatgt cctatcaaga ctatatcaac
    32221 tgctcccgtg aggccttgtt ggaaaaaatg gcagagcttc tacctgagaa acgtctaacc
    32281 cattgtctag gtgtggagcg tgctgctatg gaattagctc agcgctttgg tgtagatgtt
    32341 gagaaagcaa gtctagcagg tcttcttcat gactatgcta aaaagttgtc agatcaggaa
    32401 tttctagact tgattgaccg ttaccagcta gaccctgacc tcaaaaactg gggcaataat
    32461 gtctggcatg gtatggtcgg aatttacaaa attcaggaag atttggattt gcatgattct
    32521 gaaattctgc gagccattga aattcataca gtcggagctg gtcaaatgac agacctagat
    32581 aaggtcatct acgtcgcaga ctatatcgag cacaatcggg catttcctgg agtggatgtg
    32641 gcgcgtgaga ttgcaagtct atcgctcaat aaggcggtgg cctacgaaac agctcgtacc
    32701 gtggagtatc tagctcatca gggattcccc atctatcccc aaacccttga aacctataac
    32761 gcctttgtgc actatttgaa agagaactaa atgaagacgg cttttataat cattgatgtt
    32821 cagaatgttt tagtagaaac tgggttccag acaaaaagtc tattgggaaa aatttcttat
    32881 ttacaaaacc aggctagaag caagaatatt gaaattatct atgttcaaca tattgagaac
    32941 tctgaagctc aaacatcaga agattggcag ttatctgcgc ttttaaatcg aaaacctgct
    33001 gaaaaggtct ttcagaagaa atataacagt attttcaaag aaactggctt aaaagaatac
    33061 ttggataagc aggggattga aaaattagtt ttatgtggta tgcagacaga atattgtgtg
    33121 gatacctctg tcaaggttgc ctttgaatat ggctatcagc ttattgttcc agaaggtgct
    33181 gtcacaacct ttgatgggga tgacattcca gcagaaacga ttaatgaatt ttatgaggac
    33241 atttgggagg agcgctttgc agatgtccta gattacaaac atattttcta aaaagaggat
    33301 taaatgaacg aaaaagaatt actagaacta gtcgtgaaag cggctgatga gaaacgtgcg
    33361 gaggatatcc tcgcacttga tgtacaagat ttgactagtg tgacggacta ctttgtcatc
    33421 actagctcaa tgaatagccg tcagttggac gctatcgcag ctaatatccg tgaaaaagta
    33481 gctcaagcag gctttaaagg tagccatgtc gaaggcgatg cagctggagg ctgggtctta
    33541 ctggacctcg gtgctgttgt cgtgcatatc ttttcagaag aaatgcgtgc ccattataat
    33601 ctagagaagc tatggcatga ggcgaattca gtagatattt cagaagctct tgcttagaag
    33661 atgaactcag ttgtagtcaa ctgggtttct ttgcttattt tagaaaaatt gatagaaagg
    33721 taaagggcta gtggtgttta ccatggagct cttagtatca tgattatggc gacttatgaa
    33781 acctttgcgg cggtctatga tgcggtcatg gacgatagtt tatacgacaa atggacgaat
    33841 ttttctctgc gtcatttgcc taagaccaag gagagaaaga aactcttgga attggcttgt
    33901 gggacaggaa ttcaatcagt gcgcttctct caggctggtt ttgatgtgac tggacttgac
    33961 ttgagtgcgg atatgttgaa gattgcggag aagagagcaa cttcagccaa gcaaaagatt
    34021 acttttatag aaggtaatat gctgaatttg tccaatgcag ggaaatacga ttttgtcacg
    34081 tgttattcgg actctatctg ctatatgcag gatgaggtgg aagtagggga cgtctttaag
    34141 gacgtgtaca atgcgctgaa tgaagaggga gttttcatct ttgacgtgca ctcgacctac
    34201 cagacagatg aagtattccc tggctattcc taccatgaaa atgcggaaga ttttgccatg
    34261 ctttgggata catatgagga cgaagctcct cactccatcg tgcatgagct gactttcttt
    34321 atcaaggagg ctgacggttc ctttagtcgt catgatgaag tacatgagga gaggacctat
    34381 gagatcttga cctatgatat cttgctggaa caggctggat ttaagtcttt caaactctat
    34441 gcagactttg aggataagga gccaacagaa actagcaccc gttggttttt tgtggcgcag
    34501 aagtaggaga acatcatgac catcacaggt attatcgcag agttcaatcc ttttcataat
    34561 ggccataaat acctgctgga tcaggcagag ggactgaaaa ttgttgccat gtcagggaat
    34621 ttcatgcagc gtggagagcc tgctattgtg gataagtgga caagggccca gatggcgctg
    34681 gaaaatggcg cagacttggt agtggaattg ccctttttag tcagtgttca ggcagctgat
    34741 ttctttggtc aaggagctgt ggatatcttg gatcgcttgg gcattgatag tctagttttt
    34801 gggacagagg aagttcgaga ttatcagaaa atcgctgact tatacacaga gaaaggtact
    34861 gagatggaga aatttgtgga aaatctgcct gattcccttt cctatcccca gaaaacccaa
    34921 gctatgtgga aggaatttgc tggtcttgat ttttcaggta atacccccaa tcatgttctt
    34981 gctctggcct atgccaaggc ggttgcagga cggaatatca agctgcatcc gattcagcgt
    35041 cagggggcag gttaccattc tgtgaataaa gatgtggact ttgcctcggc gacagccctc
    35101 cgtcaacatc agaaggacca agatttctta gaacgtttta tgccttctgt tgccctattt
    35161 gagcaggcca gtaaggtgat ctgggaagac tattttccct tgctccgcta tcaaatcttg
    35221 tcaaatcccg acttaaccac catctatcag gtcaatcaag aaatggctgt gcgcattaaa
    35281 gaagctatta aaacagccca gtctgtggaa gaattggtcg agttagtgac taccaaacgt
    35341 tacaccaagg cgcgtgtcag acgcctattg acctatattt tgatgcaggc tagagaaaat
    35401 gtcttgccag aagccattca tgtccttgga tttactgaaa aaggtaggca acatctcaag
    35461 tctttgaaag gtcaggtcag tctagtcagc cgaattggca aagaaccttg ggatgctatg
    35521 acccaaaaag cagaccagat ttaccaacta ggaaagccaa gtatagcaga gcaaaatttt
    35581 ggaagagtgc cgattagaat agaaacaaac taagtctacc gaaaggtgga ctttttgaga
    35641 ttttttacga ataatactct tcgaaaatca aattcaaatc gcgtcaacgt cgccttgccg
    35701 tactcaagta cagcctgcgg ctagtttcct agtttgctct ttgattttca ttgagtataa
    35761 atagatagaa aagaaaatct tgtacaagtt cctgacaatt tctttctttt cgtgtataat
    35821 agtggaaaag agctaaaacg aggtatggtt atggaagcag tcctttactc aacattccga
    35881 aatcatttaa aggactacat gaagaaggta aatgatgaat ttgagccttt gacggtggtc
    35941 aataaaaatc cagatgagga cattgtagtt ctttcaaaga gcgaatggga cagtattcag
    36001 gaaaccctga gaatcgccca aaataaggag ttatcagaca aggttttacg aggaatggat
    36061 aaaattcgcg caggacacta gtctaattta cagagaatac ctgagtgaaa tcttgctgtt
    36121 gttagaaaca aacttcttgt atttcataat cattaggaag tctactgcaa agtaggcttt
    36181 ttctcaagtc tctactaaac tactatttct aaaaaacaag tttattttgg taaatgtgtt
    36241 ccaaattccc caaaacatat tctattttag gtttgtgaaa atcacttttt tatggtagaa
    36301 tgtaaaagaa tgtatgtcat tcggaataac aataaaatga ggtaaaaaca tggagatcat
    36361 gtcgcttgcg attgctgttt ttgccgtcat cattggttta gtcattggat atgtcagcat
    36421 ctcagctaag atgaaatcat ctcaggaagc tgcagagttg atgcttttaa atgctgaaca
    36481 agaagcaact aatttacgtg gacaagctga gcgtgaagcg gatttactta ttaatgaagc
    36541 caaacgtgaa agcaagtctc ttaaaaaaga agcactattg gaggccaaag aagaagccag
    36601 aaaataccgt gaagaagtgg acgctgaatt caaatcagaa cgtcaagaac tcaaacaaat
    36661 cgaaagtcgt ttgacagaga gagctactag ccttgaccgt aaggacgaca atttgacgag
    36721 taaagaacaa acacttgaac aaaaagaaca aagtatttct gatagagcga aaaaccttga
    36781 tgcgcgtgaa gagcaattag aggaagtcga aagacaaaaa gaagcagaac tagagcgtat
    36841 tggtgctctg tctcaggcag aagcacgaga tattatcttg gctcagacag aggaaaactt
    36901 gaccagggag attgccagtc gcattcgcga agctgagcaa gaggtcaagg aacgttctga
    36961 caaaatggcc aaggacatct tggttcaagc tatgcaacgt atcgctggtg aatatgtagc
    37021 ggagtcaaca aactcaacag ttcatctgcc agacgatact atgaagggac gcattattgg
    37081 tcgtgaaggt cgtaacattc gtacctttga aagtttgaca ggggtcgatg tgattatcga
    37141 cgatacacca gaagtggtga ccttgtcagg atttgatccg attcgtcgtg agattgcccg
    37201 tatgactatg gaaatgttgc tcaaagatgg tcgtatacat ccagctcgta tcgaagagtt
    37261 ggttgagaaa aaccgtcaag agattgacaa taagattcgt gaatacggtg aggctgctgc
    37321 ctatgaaatt ggtgcgccaa accttcatcc agacttgatg aagattatgg gacgtttgca
    37381 gttccgtact tcatatggac aaaatgtttt gcgccattcg attgaggttg ctaagttggc
    37441 tggtatcatg gcgagcgaac ttggtgaaaa tgcggctctt gcccgtcgtg ctggattcct
    37501 tcacgatatc gggaaagcca ttgaccatga ggttgaaggt agccacgttg aaatcggtat
    37561 ggaattggcc cgtaagtaca aggaaccccc agttgtggtg aatacgattg ctagtcacca
    37621 cggagatgtt gaagctgaga gcgtgatagc agttatcgtc gctgcagcag atgccttgag
    37681 cgcagcccgt ccaggtgctc gtagtgagtc tcttgaaagc tacatcaagc gtctccatga
    37741 tttggaagaa attgctaacg gctttgaagg agtgcaaact agctttgccc ttcaagcagg
    37801 acgtgaaatt cgtatcatgg tcaatccagg aaaaatcaag gacgacaaag tcacaatctt
    37861 ggctcacaaa gttcgtaaga aaattgaaaa caatctcgat tatccaggaa atatcaaggt
    37921 aaccgtgatt cgcgagcttc gtgcagtaga ttatgctaaa taaataagaa agagcagttg
    37981 aaaaattact gcttttttgt tacactagat agaaagactg taaaggataa tctggctttt
    38041 tgccattatt ctagagaaat gttatttcac agattgacta aaaggagaca caatggcaga
    38101 ccgaggctta ctaatcgttt tttctggtcc ttcaggggtt ggaaaaggaa cggttagaag
    38161 agagattttt gagagttctg aaaaccaatt tcaatactct gtatcgatga cgacacgcgc
    38221 acaacgtcct ggagaagtgg acggtgttga ctatttcttc cgtactcgtg aagaatttga
    38281 agagctgatt cgtcaaggac agatgttgga atacgcagaa tatgtcggta actactatgg
    38341 aactcctctg acctatgtca atgaaacctt ggacaaggga atcgatgttt tccttgaaat
    38401 tgaagttcag ggtgctcttc aggtcaagaa aaaggttcca gatgctgtct ttatcttcct
    38461 gacaccacca gatttggatg aattgcaaga tcgcttggta ggtcgtggaa cagatagtgc
    38521 agaagtgatt gcccaacgaa tcgaaaaggc caaggaagaa attgccctca tgcgtgagta
    38581 tgattatgcc attgtcaacg atcaggtgtc cctagctgct gaacgtgtca aatgtgtgat
    38641 tgaagcagaa cacttctgtg tggatcgtgt cattggtcac tatcaggaga tgttaccaaa
    38701 atctccaact acccgataaa atttagaaaa taggtacaag caaatgatgt taaaaccctc
    38761 tattgatacc ttgctcgaca aggttccttc aaaatattca ctcgtaatct tggaagcaaa
    38821 acgtgcccac gaattggaag caggtgcccc agcaactcaa ggtttcaagt ctgaaaaatc
    38881 aactcttcgc gctttagaag aaatcgaatc aggaaacgtt acaattcacc cagatccaga
    38941 aggaaaacgt gaagcagtgc gtcgccgtat cgaagaagaa aaacgccgca aagaagaaga
    39001 agaaaagaaa atcaaagagc aaattgctaa agaaaaagaa gatggtgaaa aaatttaagg
    39061 ttggggggac tcaatcttat tttttctatt gcaagaatgt actgacaagg aggaggtgag
    39121 aagatggccc tagctaagat tatcgtagat gtgcccttga tgcagacgga ccagccctat
    39181 agttacagga ttccggagga atttgaggga atgctggaag ttgggatgcg ggttcatgtg
    39241 ccttttggta agggtaatcg cctgattcaa gggattgttc ttggtttgga gtcccaatca
    39301 gatggagaag agatggagca agatttaaaa gatattgcag aggtgctgga tttttctcct
    39361 gttctcacgc cagaacaact ctggctggct gaggagttac gcaaatctgt cttctcctac
    39421 aaaatttcta tcctcaaggc catgcttcca ggatttctga attctagcta tgacaagatt
    39481 ctctatcctc tggaaggctt gagtcaggaa gaacgagtgc gcctgtttgg ttcagaagat
    39541 tcgctagcct tttcttcact agaccttgcc aagcaagctg aaatgatgcg tttgactaga
    39601 aaaggcctgc ttgttctgga atatcaggca gtcgatcaaa agaaggtcaa gacccagtct
    39661 tggtatgagg ttgaccatgc tcaattagaa ggtgttgaga tttctacacg tgccaagaaa
    39721 aagttggaac tgagagatta tctgctgtct catccagaga gcgcttcctt ggctagcttg
    39781 ttagagtcct actcgcgaga gcaagtcaac ttctttgtgg atcaaggtgc tgttaccata
    39841 gtccaaaagg aagttcaacg ctcggctgct tattttgaag gaattgaagc aagtagacct
    39901 ttggagttaa atccagaaca aagacaggcg cgtgatgcgg ttgtgagttc tattggcagt
    39961 tctcaacctc cctttctact tcaagggatt acaggaagtg ggaagaccga ggtttacttg
    40021 cagattatcc aaggtgccct ggataagggc aagacagcta ttttgctggt acctgagatt
    40081 tccttgactc ctcagatgac cgagcgtttt atagcacgtt ttggggacaa ggtagccatt
    40141 cttcactcag gattatccaa tggtgaaaag tatgatgaat ggcgcaaggt ggagcgtggc
    40201 gatgcccaag ttgttgttgg tgccagatct gctatctttg ctcctctgaa aaatctgggt
    40261 gtcatgatta ttgatgaaga gcatgaagcg gcttataagc aggacagcaa tccccgttac
    40321 catgccagag aggtagctat tttacgggct cagtataatc aagcaactct ggtacttgga
    40381 tctgcaacgc cgagcttaga gagccgggca cgtgctggca aaggcgtcta tcaacactta
    40441 cgtctaaccc aacgtgccaa tcctttggct acaatccctg aggttcaagt gattgacttt
    40501 cgagactata tcggacaaaa tgagacgtca aactttacgc ctcctttgct agaggctatc
    40561 caagaccgtc tggttaaaaa agagcaggtg gttctcatgc tcaatcgccg tggttattct
    40621 agctttgtca tgtgtcggga gtgtgggacg gtggatactt gtcccaactg cgatatttct
    40681 ctgaccttgc atatggatac caagactatg aactgccatt attgtggttt ctcgaaggat
    40741 attcctcagg tctgtcctaa ctgtaagagc cgcagtattc gttactatgg gacgggaact
    40801 cagaaggctt atgatgagct agcagaactc tttccccaag ctcgcatttt gaggatggat
    40861 gtggatacga ctcgaaagaa aggcagtcac caagccttgc ttgaccagtt tgggcgaggg
    40921 gaagcggata ttttacttgg tactcagatg attgcaaagg gtttggattt tcccaatgtt
    40981 accctagtcg gagttctaaa tgcggatacg gccttgaatc tgcctgattt ccgttcttct
    41041 gagagaacct tccagctctt gactcaggtg gcaggtcgag caggtcgggc tgaaaaagca
    41101 ggtcaagtct tgatacagtc ctacaattcg cagcactatg ctattcgatt tgccaaggat
    41161 caagattacg aaggctttta tgcctatgaa atgggaatca gacgacaact cggctatcca
    41221 ccttactatt tcacgattgg tattaccctt tctcacaaga aagaagaaga ggttttcaaa
    41281 cgtgcctatg aagtcatgaa cattttgcgg tcaggcttgt cagagaccag tcccattctg
    41341 gggccaacgc caaaaccgat tgcccgtacc cacaacctct atcattacca gattttaatt
    41401 aaataccgtt tagaagatga gctggggccg accctcaacc aggtcttggc cttgactcaa
    41461 gaacgggaaa atagtgagct ccgtctcagc attgaccatg agccgcagca atttttataa
    41521 gaaggagaag atatgacaaa actaatcttt atggggaccc ccgacttttc agcaacagtc
    41581 ttaaaaggac ttttgacaga tgaccgttac gaaattctag ccgttgtgac ccagccagac
    41641 cgtgctgttg gtcgtaaaaa agttatccaa gaaaccccag tcaagcaggc tgccaaggaa
    41701 gcaggactat ctatctacca acctgaaaaa ttatctggaa gtccagagat ggaagatctt
    41761 atgaagctag gagcagatgg aattgtgact gctgcttttg ggcagtttct cccaagcaaa
    41821 ctccttgata gcatggactt tgctgtcaac gttcatgcct ccctccttcc tagacaccgt
    41881 ggtggtgcgc ctatccatta tgccttgatt caaggggatg aggaagctgg tgtgaccatc
    41941 atggaaatgg ttaaggaaat ggatgcagga gatatgattt ctcgtcgcag cattccgatc
    42001 acagatgagg acaatgttgg caccttgttt gaaaaattgg cgctagttgg tcgtgatttg
    42061 cttttggaca ctctgcctgc ctatattgct ggtgatatca aacctgaacc gcaggatacg
    42121 agtcaggtta ccttctctcc aaatataaag ccagaggaag aaaaactgga ctggaacaaa
    42181 accaatcgtc aactctttaa ccaaattcgt ggaatgaacc cctggcctgt tgcccatact
    42241 ttccttaagg gcgaccgctt taagatttat gaagccctac cagtagaagg tcagggaaat
    42301 ccaggtgaga ttctctctat cggcaagaaa gaattgattg tcgcaacggc tgaaggggct
    42361 ctatccctca aacaagtgca gccagctggt aagcctaaga tggacattgc ttccttcctc
    42421 aacggagttg gacgtacatt gactgtagga gaacgatttg gtgactaaag tagaaacggc
    42481 tagaagttta gctctagcag tgctagagga tgtttttgtg aaccaagcat actcaaatat
    42541 cgccttaaat aagcatctaa aggggagtca acttttggca gcagacaagg gcttagtgac
    42601 cgagctggtc tatggaacgg tagcccgtaa actgactctg gaatggtacc tatcccactt
    42661 tatcgaagac agagaccagt tagacagctg gctctatgtc cttcttctca tgagtgccta
    42721 ccaactccgc tatttggaca agattccaga tcatgctgtg gtcaatgaag cagtggaatt
    42781 ggccaaactt cgtaaaaaag gcagtgaaaa attggtcaat gccctccttc gccgtatctt
    42841 gcgtgaaggc tggccagata tttctagcat caagcgaaaa aacaagcgtg actccattgc
    42901 ctattctctc ccagtttggc tagttgccaa actcaaggaa gaatacggag aggagagagc
    42961 aaaagccatc tttgaaagct tgttagtgcg aaacaaagcc agtattcgtg taacagacct
    43021 aagtcgaaaa gaggaaatcc aagccttgtt ggaggcgaat aattcccttt tagcaaccac
    43081 tggtctggtt aaggagcaag ggcattttgc agggcataac ttgtttgcgg atggagccat
    43141 taccatccaa gacgagtcca gtcagctggt tgctccgacg cttgatttac aaggtgatga
    43201 gcgagtgctt gatgcctgtg cggctccagg tgggaaaaca gcccatatag cctcttatct
    43261 tacgacaggt caggttactg ctctggactt gtacgaccac aagttggatt taattcaaga
    43321 aaatgcccaa cgtctgggag ttgaagatcg ggttcaaact caaaaattgg atgccagaaa
    43381 ggtgcatgag ttttttgacc aggattcctt tgataagatt ttggtggatg ctccttgttc
    43441 aggaatcggt cttttgcgcc gaaaaccaga tatcaaatac aataaagaaa cggcagattt
    43501 cgcgtccttg caggaaattc agttagaaat attaggtagt gtttgtcaaa tactaggcaa
    43561 aggtggtata ataacttata gcacctgcac tatcgtctca gaggagaatt ttcaagtcgt
    43621 taaggccttt ttagagagtc atcccgagtt cgagcaggta aaactagaac atgaatgtaa
    43681 ggatatcatg aaagacggct gtatcctcat tacacctgaa ttgtatggaa gtgatggatt
    43741 cttcatcagt caatttcgca agatatcgga ttaggaagga actgacacat ggaaatttca
    43801 ttattaacag atgttggtca gaaacgaaca aataaccaag actatgtcaa ccactatgtc
    43861 aatagagctg gacgtaccat gattatttta gctgatggga tgggaggtca tcgtgcaggg
    43921 aatatcgcta gtgaaatggc ggtcacagac ctgggtgtag cttgggttga tacccagatc
    43981 gatacagtca atgaagtgcg tgaatggttc gcccattacc tagaaattga aaatcaaaag
    44041 attcaccagc ttggtcagga tgaagcttac agaggcatgg gaactacttt ggaagtcctt
    44101 gctattattg ataatcaggc tatctatgct catattggtg attcgcgtat cggcttgatt
    44161 cgtggagaag aataccatca gttgacgagc gatcattcct tggttaatga attgctcaag
    44221 gctggtcaat tgacaccaga agaggcagaa gctcatccgc aaaaaaatat tatcacccag
    44281 tctattgggc aaaaagatga aattcagcct gattttggga cagttatcct tgagtcaggt
    44341 gactatctct tgctcaatag tgacggcttg accaacatga tttcaggcag tgagattcgt
    44401 gatattgtaa ccagtgatat tcctttagca gataaaacgg agacacttgt tcgttttgct
    44461 aacaatgcag gaggtttaga caacattacg gttgcccttg tttctatgaa cgaggaggat
    44521 gcagaatgat ccaaatcggc aagatttttg ccggacgcta tcggattgtc aaacagattg
    44581 gtcgaggagg catggcggat gtctacctag ccaaagactt aatcttagat ggggaagaag
    44641 tggcagtgaa ggttctgagg accaactacc agacggaccc gatagctgta gctcgttttc
    44701 agcgtgaagc gagagctatg gcagatctag accatcctca tatcgttcgg ataacagata
    44761 ttggcgagga agacggtcaa cagtacctag ctatggagta tgtggctgga ctggacctca
    44821 aacgctatat caaggaacat tatcctcttt ctaatgaaga agcagtccgt atcatgggac
    44881 aaattctctt ggctatgcgc ttggcccata ctcgaggaat tgttcacagg gacttgaaac
    44941 ctcaaaatat ccttttgaca ccagatggga ctgccaaggt cacagacttt gggattgctg
    45001 tagcctttgc agagacaagt ctgacccaga ctaactcgat gttgggctca gttcattact
    45061 tgtcaccaga gcaggcgcgt ggttcgaagg cgactgtgca gagtgatatc tatgccatgg
    45121 ggattatttt ctatgagatg ttgacaggcc atatccctta tgacggggat agcgcggtga
    45181 ccattgccct ccagcatttc cagaaacccc tgccgtccgt tattgcagaa aatccatctg
    45241 tacctcaggc tttagaaaat gttattatca aggcaactgc taaaaagttg accaatcgct
    45301 accgctcggt ttcagagatg tatgtggact tgtctagtag cttgtcctac aatcgtagaa
    45361 atgaaagtaa gttaatcttt gatgaaacga gcaaggcaga taccaagacc ttgccgaagg
    45421 tttctcagag taccttgaca tctattccta aggttcaagc gcagacagaa cacaaatcaa
    45481 tcaaaaaccc aagtcaggct gtgacagagg aaacttacca accacaagca ccgaaaaaac
    45541 atagatttaa gatgcgttac ctgattttgt tggccagcct tgtattggtg gcagcttctc
    45601 ttatttggat actatccaga actcctgcaa ccattgccat tccagatgtg gcaggtcaga
    45661 cagttgcaga ggccaaggca acgctcaaaa aagccaattt tgagattggt gaggagaaga
    45721 cagaggctag tgaaaaggtg gaagaagggc ggattatccg tacagatcct ggcgctggaa
    45781 ctggtcgaaa agaaggaacg aaaatcaatt tggttgtctc atcaggcaaa caatccttcc
    45841 aaattagtaa ttatgtcggc cggaaatctt ctgatgttat cgcggaatta aaagagaaaa
    45901 aagttccaga taatttgatt aaaattgagg aagaagagtc gaatgagagt gaggctggaa
    45961 cggtcttgaa gcaaagtcta ccagaaggta cgacctatga cttgagcaag gcaactcaaa
    46021 ttgttttgac agtagctaaa aaagctacga cgattcaatt agggaactat attggacgga
    46081 actctacaga agtaatctca gaacttaagc agaagaaggt tcctgagaat ttgattaaga
    46141 tagaggaaga agagtccagc gaaagcgaac caggaacgat tatgaaacaa agtccaggtg
    46201 ccggaacgac ttatgatgtg agtaaaccta ctcaaattgt cttgacagta gctaaaaaag
    46261 ttacaagtgt tgccatgccg agttacattg gttccagctt ggagtttact aagaacaatt
    46321 tgattcaaat tgttgggatt aaggaagcta atatagaagt tgtagaagtg acgacagcgc
    46381 ctgcaggtag tgcagaaggc atggttgttg aacaaagtcc tagagcaggt gaaaaggtag
    46441 acctcaataa gactagagtc aagatttcaa tctacaaacc taaaacaact tcagctactc
    46501 cttaaaagca gatggataat caaaatgagt aatcaatctt tgtcatgatt tcatggcaaa
    46561 gatttttttt gagtccggat ttgtgataga atagagggag ttgataaaag gaggaaagca
    46621 tggaagaatc aaaagaatta aatgccgtca ttgatgtgat tatgctagcg gggactattc
    46681 tccttaaaag tggctcagaa atccatcgtg tagaagatac catgattcga atcgcgcatt
    46741 cgcaggggat tgtggattgc aatgtccttg ccatgcctgc cgctatcttt ttctctattg
    46801 aaaataccaa tatttcgcgc atgaagcgcg tgacctcctc ttcttataac attgaaaaag
    46861 tctgcgatgt gaaccagatt tctcgtcagc tagttggggg gcagattgac ttagaaacag
    46921 cctttaagca attgacggcc ttgcaagctc aaccccttcc ctatactaag ttgcaggtaa
    46981 ctctggctgc gacctttagt gctcctttct tttcagttat gtttagcgga aatatctacg
    47041 acgcacttgg ggcaggagtg gcgaccttat ttggttttgc cttttccctc tatgtggaaa
    47101 aatttatccg aattcccttt gtgacagcct ttgctggagc ctttgtcttt gggataattg
    47161 cccagttttg ggctcgctac acaggttttc cttcaacggc agatttgatt atagctggtg
    47221 cggtcatgcc gtttgtacca ggtattgcct tgaccaatgc ggtccgtgat attatgacca
    47281 accacataaa ctctggtatg agtaagatgt ttgaatccct gctcattacc ctcgctttag
    47341 gggcaggaac ttctgtcgcc ttggtattga tgaactaata tgacactaac aaccttttta
    47401 ttacaagcag tagcaagttt tcttgccatt atcacttttt taattgtact caatgtgcaa
    47461 cggtctatgc tcttacctgg agggattttg ggcatgactg tctggctaat ctatctcttg
    47521 ctcaaggaac cgaccaatgt cattgtagct accttcattg cagccattat tggttcttgt
    47581 gtcagccaga ttttaagtat tctttataag acacctgctg tggtctttat cttggccatt
    47641 ttggcaccgc tggttccagg ttatctctcc taccgaacaa ctgccttttt tgtgacaggg
    47701 gactataata aagcactggc aagtgcgacc ttggttgtca tgttggcttt ggtaatctct
    47761 attggaatgg ctagcggaac agtgattctc agactgtatc attatataaa aacacatcga
    47821 gtatcgtaga ctttacagaa ataaaagaat tttctgaaaa atgagataaa taaattaaca
    47881 acgctttcta tatgtgcgag aataccgcac ttatgaagaa attgcggctg attttggtat
    47941 ccacgaaagc aacttactcc gtcggagcca atgggttgaa gtaactcttg ttcaaaggtg
    48001 gtgttacgat ttcaagaact cctctcagtt ctgaggacac ggtaatgatt gatgcgacgg
    48061 aagtacaaat caatcgccct aaaaaaagaa ttagcgaatg attctggtaa aaagaaatgc
    48121 cacgctatga aggctcaagc gattgtcaca agtcaaggga gaattgtttc tttggatatc
    48181 actgtgaact attgtcatga tatgaagttg ttcaaaatga gttgcagaaa tatcggacaa
    48241 gctggtaaaa tcttggctga cagtggttat caagggctca tgaagatata tcctcaagcc
    48301 actaacagct gaagataaaa cctataacca tgcgctatcc aaggagagaa gcaaggttga
    48361 gaacatcttt gccaaagtaa aaacgtttaa aatgatttca acaacctatc gaaatcatcg
    48421 taaacgcttc ggattacgaa tgaatttgat tgctgagaag gttagtaaaa cacttgacaa
    48481 gacatttgat aaggatgtca gagaaattcc gaccagtcag ttttatcaaa aatttgtaga
    48541 tgagatggga aggacttact caggaaattt gatcctccag gagctgataa ctgtgaatgg
    48601 agcttataaa gctacttata tcggtgaact ctctagcaac taatcattct ttaaaatgat
    48661 gaccaataag aggcttgatt tggtgaatca agtctttttt ctctctttta ctgccatttg
    48721 tgataaaata gtatagaacg attttttaca tgaatgataa aacagaggta aatatgacaa
    48781 tcggtattga taagattggt tttgcgacca gtcaatatgt cttgaaatta caagacttag
    48841 cagaagcgag gggaattgac cctgaaaaat taagtaaagg actcttactc aaggaattga
    48901 gtattgcgcc cctaactgag gacatcgtga ccttggcggc cagtgctagt gactctattt
    48961 taactgagca agaaagacaa gaagttgaca tggtcattgt ggcgaccgag tcaggaattg
    49021 accagagtaa ggctgcggcc gtctttgtgc atggcttgct gggcatccag ccctttgctc
    49081 gtagtttcga gattaaagaa gcctgctatg gggcgactgc tgccctccat tatgccaaat
    49141 tgcatgtgga aaattctccg gagtccaagg tcttggtcat tgcaagtgat attgccaaat
    49201 acggtattga aactccggga gaacccactc agggtgccgg aagtgtggct atgttgatta
    49261 cacaaaatcc acgcatgatg gcctttaata atgacaatgt agctcagacc cgtgacatca
    49321 tggatttctg gcgaccaaat tactcgacaa ctccttatgt aaatggtgtc tattctaccc
    49381 aacaatactt ggatagtttg aaaacgactt ggcttgaata tcaaaaacgc taccagctta
    49441 ctttggatga ttttgcggct gtttgtttcc acttgcctta tcctaaatta gcgctaaaag
    49501 gcttgaaaaa aatcatggat aagagcctgc ctcaagagaa aaaagacctc ttacaaaagc
    49561 attttgacca gtctattctc tacagtcaaa aggtggggaa tatctacaca ggttcacttt
    49621 tccttggact tttgtctctc ttggaaaata cagatagctt gaaagctggg gataaaatcg
    49681 ccctttatag ttacggaagt ggagctgtgg ctgagttctt cagtggtgaa ttggttgaag
    49741 gatatgaagc ttatttggat aaagaccgct tgaacaagct caaccaacga actgtcttat
    49801 ccgttgcaga ctatgaaaag gtcttttttg aggaagtaaa cttggatgaa acaaactctg
    49861 cccagtttgc tggctatgaa aatcaagatt ttgccttggt tgaaattctc gaccaccaac
    49921 gccgttatag caaggttgaa aaataatgaa gataagttgg aatggatttt ctaaaaaatc
    49981 ataccaagag cgcctcgagc tgttaaaagc tcaggcgctc cttagtcctg agagacaagc
    50041 tagtctggag aaggatgaac agatgagcgt gactgtggca gaccagctga gtgagaatgt
    50101 agtgggaact ttttctctgc cttattcact ggttccggag gtacttgtca acggtcagga
    50161 atacaccgtt ccctatgtga cagaagaacc ctctgtggtt gcggcggcca gctatgccag
    50221 caaaatcatc aagcgtgcag gtggttttac tgcacaagtc catcagcgac agatgattgg
    50281 gcaggtagcc ctttatcaag ttgctaatcc taaactagcg caagagaaga ttgccagcaa
    50341 gaaagcggag ctcttggagc ttgccaatca agcctatcct tctatcgtta aacgtggagg
    50401 tggggcgcgt gatctgcatg tcgagcagat aaaaggcgaa ccagactttc tcgttgttta
    50461 tattcatgtc gatacccagg aagccatggg tgccaatatg ctcaacacca tgctggaagc
    50521 cttgaaacca gtcttagaag aactcagtca gggacagagt ctcatgggaa tcctgtccaa
    50581 ctacgcgacc gattctctgg tgactgcaag ctgtcgcatc gcctttcgct acttgagccg
    50641 ccaaaaggat caaggacgag agattgcgga gaaaattgcg ttggctagtc agtttgcgca
    50701 ggctgatcct taccgagctg ctactcataa taaaggaatt tttaatggta ttgatgcgat
    50761 tttgattgcc actggtaatg actggcgtgc catcgaagct ggggcccatg cctttgccag
    50821 tcgagatgga cgctatcaag gtcttagttg ctggacgctg gaccttgaaa gagaagaatt
    50881 ggtcggtgag atgaccctgc ccatgcctgt agcgactaag ggtggctcta tcggcctcaa
    50941 cccacgtgta gctctcagtc atgatctact aggaaatcct tctgccagag aattagccca
    51001 gattatcgtg tccatcggtc ttgcccaaaa ttttgcagcc ctcaaagcct tggtaagtac
    51061 gggcatccag caaggccaca tgaaactaca ggccaaatcc ctagctctcc tagctggggc
    51121 tagtgaatct gaagttgctc ccctagtaga gcgcctcatc tcagataaaa cctttaacct
    51181 agagacagcc cagcgctatc tcgaaaattt aagatcataa aaactcagac gaatcggtct
    51241 gagttttctt gtgtttaaat actttttcct ggtaatagtg taactggtaa gaagtaacca
    51301 gttgtggcga cttccttgcc ttcaatcttt tgcaagagaa gatcaatagt gagacaagca
    51361 atctcttcca aaggttgctt gatagtagcc aattgagggt agtaattttc gataaagtag
    51421 gtcccatcat agccgataac cttgagctct tttgggacag aaatgcccaa ttcttgagcg
    51481 attttaatga tcagaatagc tgtcaaatca tccgaagcaa aaatggcatc tggtttttcc
    51541 cgggtcaaga tattcttgat ttccatttct tttctgacgg gagaaaagtc actggaaaca
    51601 ttgataatag gagcttttgg gagtacggat gcaaaaccag cgtggcgcag tccggttggc
    51661 gaattggaat tgtcattccc tgtaatcatg atgatagact gggcacctgt cttgaccaag
    51721 gtttgggcag caagaacccc accagcatag ttgtcagagg agacaacagg gatgtctggc
    51781 gataggtttc ggtcaaagga aataatcggc gctgtcacac gattgtagtc ttcgattcct
    51841 aggttgtgac taccagaaat gatgccgtct acctgattgg cttccaacat ttcgatgtat
    51901 tcgcgttcct tctcagaatc atgttcactg ttgcagatga tggtcttgta accatttttg
    51961 aagagttggt gttccaattt atcaatcaat tctgcataga aaacattgga aatattgggg
    52021 aaaatcaagc cgattaactt agctgatttt ccttgcagac tacgagccag gttgttgggt
    52081 ttatagccta attctctcat ggcttcattg actttttgga tggttttctc agatagatat
    52141 ccttttttat tgataacccg agaaacggta gtaggactga cgcctgcaag tttggcgaca
    52201 tcagttagtt ttgcgaccat aatctaattc atagtaagtt ccagttgggt ttccagattt
    52261 gatcaggata ccattttggt ccgcatgtgg gaagacacga ccagaaaata ctttttctcc
    52321 tttattgatg aaaatttcaa agacagagtt atcgatgaag attgtagcag tagtagcctg
    52381 attctcgata gggcaagaac gagttgtccc aaattcttgg gcatattgtt ctccagcctg
    52441 gctacgatcc actgtcactt gaccgtttac aaggtcaaag ttgattgaaa gtcccttacc
    52501 ttctttatca gcaagtaaga caatctcgct ctggctatta gcttccaagt tgagttcaag
    52561 ttcgtaagtg ttcttggttt gggaacggtt tgagaaggct tcttcagaag cacgaaggtc
    52621 cttaatagca gcgactggat actggtagag cttgtcgtct ttgatagtga gttccttgac
    52681 caaagagaag gttccttggt ggtcaaaacg gtcagatggg taagaaacat ctggcaaacc
    52741 aagccagcta actgctagag cacgcccatc aggagcgttg aaggcttgag ttgcataggc
    52801 ttcgaaaccg taatccatgt tttgaagttg agacacatct accattttgg catttttagg
    52861 gtcaaaggaa gccccgatct tatacatatt tggaaagata ttatcgtagt ctagaacttt
    52921 cttatccaat ccttgtggac agtagagaag gacaggttgt tcctctataa agaccagatt
    52981 aggacattcc atcatgtagg cagtacggtc gttagcaaag tcaaggtcgc caactgcttg
    53041 ccagtttgtg tagtcgttat tgacagcctt gtagagacgg acgaagcctt ttttctccaa
    53101 gtcctgtcca ccgacgacag catagtattg acctttaaag ttaaaaattt gtggatcgcg
    53161 gaagtggtca gtagagtctg ctggctggtc aatcaagatc ttgtcaatct ttgtaatctt
    53221 accctccttg tccatcaaag caccgatttg gtatgggtga cggatccagt tttcatcgcg
    53281 aacatttcct gtataaaata ggaataagtt atcgccaaat tgcatggcag aaccagagta
    53341 ggcaccgtgg ctatctaatg gagtatctgg taaaactttg attccagttt ctttaaagtg
    53401 aatcaaatca tcactttcta gctgtgccca agattttaaa ccgtgggctg caccaaaagg
    53461 aaaattctgg taaaagagga tccacttgcc atcaaagtaa gaaaagccat ttgggtcgtt
    53521 gagaagtcct gtttttggct caacatggta atgagtatgc catggagatt gtgccatatt
    53581 ttcctttata tgttgaattt cttcttgcgt ccaatcttga taaagtctgt aacgacgctc
    53641 agttgtccat tccattcatt cctccaaaaa tcttatcact tttaatagta actgttttcg
    53701 ataaaaaata caagcctttt atattaaaaa agagaaaaaa ctgtcaaacg attatcataa
    53761 aataaataca ggaaatcaat caaattttta cgaaaatgtg aaagataatg aaataaaata
    53821 ctttttaacc aaggtttcaa acttattttt caaggaattc ctgatgaaac agtcaaaaac
    53881 aatcaatcta aagcttgccc actaagtgga tagaatattt tttctgcaaa acgcttgaca
    53941 tatttttaaa acatgataaa ataatagtcg taagggcgaa taaaatcgct ttcaaacaag
    54001 aacaaaatgt tatataagga gatttttgca aatgaacaat caggaaattg caaaaaaagt
    54061 catcgatgcc ttgggcggac gtgaaaatgt caatagtgtt gtccactgtg cgactcgtct
    54121 acgtgtcatg gtcaaagatg aagagaaaat caataaagaa gtgattgaga acttggaaaa
    54181 agttcaaggt gctttcttta actcagggca ataccaaatt atctttggta caggtacagt
    54241 taacaaaatg tacgatgaag ttgttgtact tggcttacca acatcatcta aggatgacat
    54301 gaaagcagaa gttgctaaac aagggaactg gttccaacgt gctatccgta ctttcggtga
    54361 tgttttcgtt ccaatcatcc cagttatcgt agcgacaggt ctcttcatgg gtgtgcgtgg
    54421 tcttttcaac gctcttgaaa tgccacttcc aggtgacttt gcaacttaca cacaaatctt
    54481 gacagataca gccttcatca tcttgccagg tttggttgtg tggtcaacct tccgtgtatt
    54541 tggtggaaat cctgccgttg gtatcgttct tggtatgatg cttgtctctg gctcacttcc
    54601 aaacgcttgg gcagttgctc aaggtggtga agtaacagcg atgaacttct ttggtttcat
    54661 ccctgttgtt ggtttgcaag gttccgttct tccagccttc atcatcgggg ttgtcggagc
    54721 taaatttgaa aaagctgtcc gcaaggttgt tccagatgtc attgacctat tggtaacacc
    54781 attcgtgaca cttttggtca tgtctatcct tggactcttt gtcattggac cagttttcca
    54841 cgttgttgaa aactacatcc ttattgctac aaaagcgatt cttagcatgc catttggtct
    54901 tggtggtttc ttgattggtg gggttcacca attgatcgtc gtgtcaggtg tgcaccacat
    54961 cttcaacttg cttgaagtgc aattacttgc tgctgaccat gctaacccat tcaacgctat
    55021 catcacagct gctatgacag ctcaaggtgc tgctactgtt gcggttggtg ttaaaacaaa
    55081 aaatccaaaa ctgaaaacac ttgctttccc ggctgctctt tctgccttcc taggtattac
    55141 agagcctgct atcttcgggg tgaacttgcg cttccgtaaa ccattcttcc tttcattgat
    55201 tgctggtgca atcggtggtg gattggcttc tatccttgga cttgctggta ctggtaatgg
    55261 tatcaccatc atccctggta caatgcttta tgttggtaac ggacaacttc cacaatacct
    55321 tcttatggta gctgtatcat ttgcccttgg ttttgctctt acttacatgt ttggttacga
    55381 agatgaagta gacgcaactg cagctgcaaa acaagctgaa gtggctgaag aaaaagaaga
    55441 agttgcgcca gcagctcttc aaaatgaaac acttgtaact cctatcgtcg gtgatgttgt
    55501 cgctcttgct gatgtcaatg acccagtctt ctcaagtgga gctatgggac aaggtatcgc
    55561 tgtgaaacca agccaaggcg tggtctatgc accagctgat gctgaagttt caattgcctt
    55621 tccaacaggg cacgcttttg gtttgaaaac aagaaatggt gctgaagttt tgattcacgt
    55681 tggtattgac actgtatcta tgaacggtga cggttttgaa gcaaaagttg ctcaaggtaa
    55741 taaggtgaaa gctggtgatg ttcttggaac atttgactca aacaaaatcg ctgcagctgg
    55801 acttgatgat acaacaatgg ttatcgttac aaatacagct gactacgctt cagtagctcc
    55861 agtcgcaaca ggttcagttg cgaaggggga tgctgtgatc gaagtgaaaa tctaatcaat
    55921 cctctctaat gtgaaaacga acaaatgaca tgtttgttcg tttttattag atagtaagat
    55981 ttacagagga aaatctaaaa aatagagaca tttagacttt cgaagtatgc tataataaag
    56041 aaaataaaaa caagaggttt atcatgacaa aattatatgg aagcttggaa gcgggcggta
    56101 caaagtttgt ctgtgctgtc ggtgatgaaa actttaacgt cgtagaaaaa acacaatttc
    56161 caacaacaac tccaatcgaa acaatcgata aaaccattga gttcttctca aaattcgata
    56221 accttgctgg tcttgcagtt ggttcatttg ggccgattga tattgacaaa aactcaaaaa
    56281 cttatggctt tatcacgacg actccaaaac caaactgggc aaatgtggac ttgcttggtg
    56341 cccttcgtcg cgccctaaac gtgccaatgt acttcacaac agacgtaaac agctctgctt
    56401 acggtgaagt ggttgcccgt aacaatgctg gtggtcgtat cgaaaacttg gtttactaca
    56461 caatcggtac aggtatcggt gcaggtgtca tccaacgtgg tgagtttatc ggtggtgtgg
    56521 gtcaccctga aatgggtcat tattatgttg ctagacaccc aatggatatt gaaaaagagt
    56581 ttaagggtgt ttgtcctttc cataagggat gtctagaagg ttatgcagct ggtccaagtt
    56641 tggaagctcg tacaggtgta cgtggggaaa atattgaact caacaaccct gtttgggatg
    56701 ttcaagccta ctatatcgct caagctgcgg ttaatgcgac agtgactttc cgcccagacg
    56761 tgattgtctt tggtggaggg gtcatggctc aacaacatat gctggaccgt gtccgtgaga
    56821 aatttacatc tcttcttaat ggttacctac cagtaccaga tgtgcgtgac tatatcgtga
    56881 cgccagcagt cgcaggaaat ggttctgcca cacttgggaa ctttgttctt gcaaaagaag
    56941 tttcaaaata aagcacaaaa tccgcttggg aaaccaaacg gattttgtgg ttgaaaacaa
    57001 tatttttgag cctttcctta agtgattacg gacggtagcg actttcttcg aaattccata
    57061 cctaaacttt gatcctaatg tctcaaagtt tccgaacacc tgaaaccatt agatttcagg
    57121 tgtttctatc acggcggaaa ggctaggtaa gtcctcgcct cactatcgaa aaatatgcat
    57181 aatttccata ccaaagtata tttagtatca agctatagtt aatctacgct ttaaaaatcc
    57241 gcttgggaaa ccaaacggat tttttacgtg tcaaagcatt tgccagaaaa agtcaataat
    57301 ataggtcaga ccgtaggtat aaaccacgag ggtaaagggt ttggtcagaa tgatgatggt
    57361 catgtagcgc ttgaaactca tcttggtcag ggcagccagc atacagagaa agtcagctgg
    57421 gctaatgggc caaatcatca taaaaataaa gaagcggtca aaacgattgc ccttatctag
    57481 ccagccgatg tacttgtcgt aggtgcgctt gctgacgaca gattggacaa aggcagctcc
    57541 gtataggcgc accagataaa agataatggc acagccaatc acgatgccga tatagttgta
    57601 gatagtcccg atgatgtgcc cgtagataaa gaccccagcc accgaggtca aggcccctgg
    57661 aatgataggg acgacagtct gtaaaatctg taaaaagata aagagaggtg gaccccagat
    57721 gcctacctgc tggataaagg cagagagggt ttccttggat tgtaaaatcc cagcctgata
    57781 agcccaaata cagaaaatca aactcccaac cccaccgaca atcgatgaga tattgataac
    57841 tcgctgcaga aggggagaaa cagctttcat ttgtttatcc tgtgacatgt aaactcctca
    57901 tagatagtat atttctacta taccatattt tggaggagaa agggggaatg agtctttttt
    57961 gataaggaat agaaagtaaa tagcccttcg agacttagaa taggtctgtc aactaaaggt
    58021 tatatgcatt ctaggtttcg aataatcgca attccataaa tttaaaagca ttctaagttt
    58081 cgaatagctt atctgagata attttgaggc attcgcgctt tcgaatagtc attttcccta
    58141 aagtttagat gtattctgaa gctagaaaga ctaaaatcta aaagtagtaa gagtctctct
    58201 ctgatggacg taatttatgg ctagtatgaa tcctttgaat cgttagttaa ttttaatatt
    58261 aatcagttct gaaataatta ctaaatatag ttagatggtg aattaattat tgctaaattt
    58321 caagttcaag ttagtcatcc agaagtcttc tctgggggac ttgtagttca agcatttttt
    58381 aggatagttg ttaatccact tttcgatgaa tgcgacttcc tttgtagtcg ttttcttagt
    58441 tcccttaggc ttaggtaacc atctatgaat gagcctgttg tgattttcat tagatcctat
    58501 aggggtgtgc ataatagata tagcagattg aaactagaat agtatacatc tacttctaaa
    58561 acattgttag aaatcgattt gactgtcccg atctatttgt cctgttttta tttcatttta
    58621 ctatataatc cttagaaaac atatcggaca agcggttgaa ttccgttccg tccattagta
    58681 aataaaggat tactccttct tgaaatgaca gatgaacttg tttcttataa aaatgttgtc
    58741 tgaaactatt cgcctttttc cagaagtttt agaggaagaa aactttatga ggaaaaagga
    58801 gttactcaaa taacaattca ggattaaaaa tagacagttg aggagcggaa ggtataaatt
    58861 gagtttgcta ctgtataatg gatttatcac taatactctt cgaaaatctc ttcaaaccac
    58921 gtcagcttcg ccttgctgta gatatagtta ctgacttcgt cagttctatc cacaacctca
    58981 aaacagtgtt ttgagctgac ttcgtcagtt ttatctgcaa cctcaaagct gtactttgag
    59041 cagcctacga ctagcttcct agtttgctct ttgcttttca ttgagtataa aagtgctcca
    59101 ggctatattt tacacagcaa tagtcttcta aaaatggaca gaaatcattg taaaggctat
    59161 caaaaaggag tataatgagt gaaagaaatt tcggaggtga aagatgctag aagtaagaag
    59221 tctagagaaa agttttggat ccaagcaagt tttgtttggt attgactttc aagcgcgacc
    59281 aggtcgtatt ttgggactag tcggaaaaaa tggtgctgga aaaacaacga ttttccatag
    59341 tattttgaaa ttcctagaat atcagggaga aatcggtctg gatggtcagg atattcgtca
    59401 ggagacctat gctcggattg gttatctgcc tgaagaacgc agtctcatgc ctaaattgac
    59461 agttcttgaa caagttcgct acttggcgac tctaaaaggc atggatgcca aagaagtcaa
    59521 agaaaaactc cctcaatgga tgaagaggtt ggaagtgaaa ggaaagctga cagataaaat
    59581 caagagtctg tcaaaaggaa atcagcagaa gattcagctc attattactc tgattcatga
    59641 accagacctg attatcttgg atgagccttt tagtggattg gacccagtta atacagaatt
    59701 gctcaaacaa gtcatttttc aggaaaaaga gcgcggagca accattatct tttctgacca
    59761 tgtcatgacc aatgttgagg aactttgtga cgatattctg atgatccgag atggccgtgt
    59821 ggtcttgcac ggaccagttc aggatgtccg caatcaatac gggaaaacgc gtctctttgt
    59881 ttcaagtgaa cgaagcaagg aagaattgga aaatcttcct catgtcaaac aggtgagctt
    59941 gaccaaacaa ggcagttgga aattgatttt ggaggatgag agcgctggaa gggaactctt
    60001 cccaatcttg actcaaggtc aatatatcgc aacatttgac caacaagcgc caactatcga
    60061 tgaaatcttt aaactagaat caggagtgga agtatgagaa atatgtgggt tgtaatcaag
    60121 gaaacctatc ttcgacatgt cgagtcatgg agtttcttct ttatggtgat ttcgccgttc
    60181 ctctttttag gaatctctgt aggaattggg catctccaag gttcttctat ggctaaaaat
    60241 aataaagtgg cagtagtgac aacagtgcca tctgtagcag aaggactgaa gaatgtaaat
    60301 ggtgttaact tcgactataa agacgaagca agtgccaaag aagcaattaa agaagaaaaa
    60361 ttaaaaggtt atttgaccat tgatcaagaa gatagtgttc taaaggcagt ttatcatggc
    60421 gaaacatcgc ttgaaaatgg aattaaattt gaggttacag gtacactcaa tgaactgcaa
    60481 aatcagctta atcgttcaac tgcttccttg tctcaagagc aggaaaaacg cttagcgcag
    60541 acaattcaat tcacagaaaa gattgatgaa gccaaggaaa ataaaaagtt tattcaaaca
    60601 attgcagcag gtgccttagg attctttctt tatatgattc tgattaccta tgcgggtgta
    60661 acagctcagg aagttgccag tgaaaaaggc accaaaatta tggaagtcgt tttttctagc
    60721 ataagggcaa gtcactattt ctatgcgcgg atgatggctc tgtttctagt gattttaacg
    60781 catattggga tctatgttgt aggtggtctg gctgccgttt tgctctttaa agatttgcca
    60841 ttcttggctc agtctggtat tttggatcac ttgggagatg ctatctcact gaataccctg
    60901 ctctttattt tgatcagtct tttcatgtat gtagtcttgg cagccttcct aggatctatg
    60961 gtttctcgtc ctgaggactc agggaaagcc ttgtcgcctt tgatgatttt gattatgggt
    61021 ggtttttttg gagtgacagc tctaggtgca gctggtgaca atctcctctt gaagattggt
    61081 tcttatattc cctttatttc gaccttcttt atgccgtttc gaacgattaa tggctatgcg
    61141 gggggagcgg aagcatggat ttcacttgct attacagtga tttttgcggt ggtagcaaca
    61201 ggatttatcg gacgcatgta tgctagtctc gttcttcaaa cggatgattt agggatttgg
    61261 aaaaccttta aacgtgcctt atcttataaa tagaagagcc ttgcgaaagc gaggttttta
    61321 aaggtgaaaa gggtggaatc acgaacctaa ttatgtacac attatgtaaa caagttgctt
    61381 gaaaactcaa ttgtatagtg aactgaatct ggaataggat aatattactt ctaaaacatt
    61441 cttacaaatt gatttgaatt ccaaaatccc atcgttccgt tcttatttca ttttgcgata
    61501 tagtgaaagg aaataagtca actcacaaaa aacgcataat atcaaggatt tttaacactt
    61561 gatactatgc gttttctaat tttaaagact ttttgcctgg tctcttttgt tctatgagta
    61621 tgttacatat ctaggtaaaa attatttaaa gcaaattaac cttatttctc aagatgtagt
    61681 aggttccgag ataaaagata gctatgaata tgagttcttt aacaatggct atacctgctc
    61741 ccatatagaa atggtcattg agtcctacca gtgaattgac atagaaatta gaactaagat
    61801 tgaagaaaag ttcaataaat ccaatgacga tttggatacc aatgtaggct gcaacagcga
    61861 gtgctgtacg gtattcattg aaaagctgtc caatggaaat agccaggtag atgcagagga
    61921 ttcctgaaat ggtatttagt aggaaggata tacctgtaag aaagatctga gggagatgtg
    61981 tttctacaaa tgtaatcaca taagaaagag gaatccattc tggagctgtt aaagccagaa
    62041 taataacagc acttagagcc aatacagcgg tgctaatcaa tgaccagata aaggcaccga
    62101 ttagtttggc tgtgatgata tggtgttcag aaactggcaa ggtcaaagtc agatagcctt
    62161 gtcggtcgta gacactacct ttgaagcgtt taataatcaa gaaaatggtt gaaatcgcaa
    62221 gtgtaagcat caagccacca aagactgtag ctagaaaaag tagcatagta gcctgacttt
    62281 cttggtaagg tagattttta aagccttgtg tctgtattcc gatgagggca gaaaggacta
    62341 gcacggctgc gtagagggct aaataccact tgttaacatt tttaaattcg tagtgaacta
    62401 aattccaaaa cataaataat ctcctttgct taggccttaa attcctgacg gaagagttgg
    62461 tcaatggatt cacctgactc gtagcgaata tcatctacat ttccttgacg gacgactttt
    62521 ccgtctttta ggaagacaat ttcatccaag attggctcga tatcagaaat caagtgggta
    62581 gaaatcaaaa cggtagaagt tggtgagtag ttgttgataa tggtattgag gatataagca
    62641 cgggctgctg gatccacccc accaatgggt tcatccaaaa catagagacg agcatcacgg
    62701 ctcataacca aaatcagttg aaccttttct ttgtttcctt ttgatagttt cttgagacga
    62761 ctattttcat caatgcccag gtctgcaagt agatgatgag cgcgttcaag attgaaatct
    62821 ttatagaagg tcttgaagta ggttagggct tctttgacct tcatttgctc attgagatag
    62881 gtcgtatcag gcaaataagc tacaacggcc ttggttgctg ggcttgggtc catgtcgttg
    62941 atgaggacac gtccttgatc tggttgtaag aggccattaa ttagtttaat cagggttgtt
    63001 tttcctgagc cgtttggccc aagaaggccg acaatttttc cagctggaat gtcaagagaa
    63061 acattttcaa gggctggtgt tgctccatat gatttggata cattttcaaa tgctagtaat
    63121 gacataggct taaactcctt taatataatc actgactacg cctggtagtt cttctttttc
    63181 atagccaaaa tgggtcatgg aggaaacgaa gtgttccaat tcttcttctg ataattgttt
    63241 gcgtgactga gcgattagct ccttatcctt agtcacaaat cgtccagttg ttcgcttgct
    63301 gtagacaaat ccttctcgtt caaggtctga taaggctctt tggatggtat tgggattgac
    63361 accagcctcg ctagctagct ccctcacggt tggaagttgt tgattgggtt ccagtgtatg
    63421 ggaaacaatc tgaagcttga ttttctccat aatctgtaaa tagatgggtt ttttgttgtc
    63481 aaatgtccag gacatcttag tctcctttct cttattcttt tgtcttaatt aaataataca
    63541 acaaaacaaa aaacttgtca agcaaaaaga agaattgttt tgggaatcgc ttaaaaaatg
    63601 gtataatgaa aagaaaacga taaggaggga aaggatgcgt tgtccaaaat gtggggctac
    63661 caagtcaagt gttatcgata gtcgccaagc agaagaaggg aacaccattc gtagaagacg
    63721 agagtgcgac gagtgccaac accgttttac aacctacgaa cgagtagaag aaagaacctt
    63781 agtggttgtt aaaaaagatg gcacacggga acaattctcc agagataaaa tctttaatgg
    63841 gattatccgc tcagcccaga aacgtcctgt gtcaagtgat gaaatcaaca tggtagtcaa
    63901 tcgtatcgaa cagaaactcc gtggtcgaaa tgaaaatgaa attcaaagtg aggacattgg
    63961 ttcactcgtc atggaggagt tggctgaatt ggacgagatt acctatgtac gttttgctag
    64021 tgtctatcgt agttttaagg atgtcagtga gttagagagc ttgctccaac aaatcaccca
    64081 gtcctctaaa aagaaaaagg aaagataaat gaagccaatt gaccgttttt cttatctaaa
    64141 gaataatcgg gtgtcgcaag atacctcatc tctggtacag tgctacctcc cgattatcgg
    64201 tcaggaggca ctgagccttt atctttatac aatcagtttt tgggataatg gtagaaagga
    64261 atatcttttt tcaagtatcc tcaatcatct caactttggg atggatagac tgataaaatc
    64321 attgaaaatc ttatctgctt ttaatctctt gaccctctat caaaaggggg atgtttatca
    64381 gctagccctc catgctcctc tatctagtca agacttcttg gagcatcctg tttatcgcag
    64441 actcttagag aaaaagattg gcgactctgc tgtggaggat ttgaaagttg aaagtgctga
    64501 tggtgaagaa atacctgtct cactcaatca agtctttcca gaattggcag aactaggcag
    64561 tcaagaagac cttggtctca agaagaaagt ggccaatgat tttgacttgg aacattttcg
    64621 ccggctgatg gctcgagatg gacttcgttt tgcggatgag cagtccgatg tcttaaacct
    64681 ctttgctatt gccgaggaga agaaatggac ttggtttgaa acctatcaat tggccaagtc
    64741 aacagctgtt tctcaggtta tttcaaccaa acgcatgcgt gaaaaaattg ctcaaaaacc
    64801 agtttcctct gactttagtc ttaaggaaac aaccattatc aaagaagcca aaagtaaaac
    64861 tgccctgcag ttcttggcag aaatcaagca aacacgcaag ggaaccatta cccaaacaga
    64921 aagagaactc ttgcaacaga tggctggctt gggcttgctg gacgaagtca tcaatatcat
    64981 tcttttattg acctttaata aggtcgattc ggcaaatatc aatgagaaat atgccatgaa
    65041 ggtagccaat gactatgcct atcaaaagat tcattcggca gaaaaggcag tcttgcgcat
    65101 ccgtgagcga ggacagaaag caaaaacaca aaaacagaat cagactgccc cagtaaaaac
    65161 caatgttcct aaatggagta atcctgaata taagaatgaa accagcgagg aaactcgtct
    65221 ggaactagaa cgtaagaagc aagaactatt agctcgatta gaaaaaggag gagattagat
    65281 ggaaagtgtc ggagacgtac tcaaacgtca acccagccgt ttttattatc aagatttggt
    65341 ccagaaaatc atgaaggacc ctgatgttgc ggcttttatc cagcaagaat ccttgactcc
    65401 agaggaatta aatcgcagta tctccaagtt taatcagtac atcaccgagc gtgacaagtt
    65461 tctccgtggg gatacggatt atattgccaa aggctacaag ccgattttgg ttaagaatca
    65521 tggctatgca gatgtttcat atgaagaaac tcctgagcta atcgcggctg aaaaagaagc
    65581 ggctattaag aaccgtctca agttaatcaa tctaccagcc agtctcaaga aagctagttt
    65641 ggctcaagtt gacttggatg atttggggcg cttaccagtt tttgaaaagc tactagcctt
    65701 cgtggagcaa tatccagcta ttcgaaaagg tctttactta tatggagact ttggtgtggg
    65761 taaaagtttc atggtggcgg ccttagctca tgatttatca gaaaaacgtg gtgtttcatc
    65821 aactctcctc cactatccta gctttgtcat tgatgtcaaa aatgctatca gtgatggcaa
    65881 tgttaagacc ttggtggatg agattaagct gtctgaggtc ctgattttag atgatattgg
    65941 cgccgagcaa tcaaccgttt gggtgcgtga cgaaatcctg caggtcattc tccaatatcg
    66001 gatgcaggaa aatttaccga cctttttcac atccaacttc aactttgaag atttggagaa
    66061 gcattttgcg aaagtgaaac atggaaatga cgaaacctgg gaagccagac gggtcatgga
    66121 acgcatccgt tatttggctg aggagactcg tttagaagga gtaaaccgtc gatgacagaa
    66181 accattaaat tgatgaaggc tcatacttca gtgcgcaggt ttaaagagca agaaattccc
    66241 caagtagact taaatgagat tttgacagca gcccagatgg catcatcttg gaagaatttc
    66301 caatcctact ctgtgattgt ggtacgaagt caagagaaga aagatgcctt gtatgaattg
    66361 gtacctcaag aagccattcg ccagtctgct gttttccttc tctttgtcgg agatttgaac
    66421 cgagcagaaa agggagcccg acttcatacc gacaccttcc aaccccaagg tgtggaaggt
    66481 ctcttgatta gttcggtcga tgcagctctt gctggacaaa acgccttgtt ggcagctgaa
    66541 agcttgggct atggtggtgt gattatcggt ttggttcgat acaagtctga agaagtggca
    66601 gagctcttta acctgcctga ctacacctat tctgtctttg ggatggcact gggtgtgcca
    66661 aatcaacatc atgatatgaa accgagactg ccactagaga atgttgtctt tgaggaagaa
    66721 taccaagaac agtcaactga ggcaatccaa gcttatgacc gtgttcaggc tgactatgct
    66781 ggggcgcgtg cgaccacaag ctggagtcag cgcctagcag aacagtttgg tcaagctgaa
    66841 ccaagctcaa ctagaaaaaa tcttgaacag aagaaattat tgtagaaagt gagaaattat
    66901 ggccctacca actattgcca ttgtaggacg tcccaatgtt gggaaatcaa ccctatttaa
    66961 tcggatcgct ggtgagcgaa tctccattgt agaagatgtc gaaggagtga cacgtgaccg
    67021 tatttatgca acgggtgagt ggctcaatcg ttcttttagc atgattgata caggaggaat
    67081 tgatgatgtc gatgctcctt tcatggaaca aatcaagcac caggcagaaa ttgccatgga
    67141 agaagcagat gttatcgtct ttgtcgtgtc cggtaaggaa ggaattaccg atgcagacga
    67201 atacgtagcc cgtaagcttt ataagaccca caaaccagtt atcctcgcag ttaacaaggt
    67261 ggacaaccct gagatgcgaa atgatatcta tgatttctat gccctcggtt tgggtgaacc
    67321 actgcctatc tcatctgtcc atggtatcgg tacaggggat gtactagatg cgattgtgga
    67381 aaaccttcca aatgaatatg aagaagaaaa tccagatgtc attaagttta gcctgattgg
    67441 tcgtccaaac gttggaaaat caagcttgat caatgctatc ttgggcgaag accgtgttat
    67501 tgctagtcct gttgctggaa caactcgtga tgccattgat acccacttta cagatacaga
    67561 tggtcaagag tttaccatga ttgatacggc tggtatgcgt aagtctggta aggtttatga
    67621 aaatactgag aaatactctg ttatgcgtgc catgcgtgct attgaccgtt cagatgtggt
    67681 cttgatggtc atcaatgcgg aagaaggcat tcgtgagtac gacaagcgta tcgcaggatt
    67741 tgcccatgaa gctggtaaag ggatgattat cgtggtcaac aagtgggata cgcttgaaaa
    67801 agataaccac actatgaaaa actgggaaga agatatccgt gagcagttcc aatacctgcc
    67861 ttacgcaccg attatctttg tatcagcttt aaccaagcaa cgtctccaca aacttcctga
    67921 gatgattaag caaatcagcg aaagtcaaaa tacacgtatt ccatcagctg tcttgaacga
    67981 tgtcatcatg gatgccattg ccatcaaccc aacaccgaca gacaaaggaa aacgtctcaa
    68041 gattttctat gcgacccaag tggcaaccaa accaccaacc tttgtcatct ttgtcaatga
    68101 agaagaactc atgcactttt cttacctgcg tttcttggaa aatcaaatcc gcaaggcctt
    68161 tgtttttgag ggaacaccga ttcatctcat cgcaagaaaa cgcaaataaa aaagtagaat
    68221 ctggaatgac agttccggat ttttttgata taataaaata atagaaaacg ctatcaaaag
    68281 aaggagggtg atgtcggtga tggaacattt gtttaaattc ttacttttag caccgtactt
    68341 ttattttgat aactggattg aaaaggccaa cagaaatagt aagttttttc caatttttta
    68401 ttatttttac tggttttaca tccccttcta ttctcttttt agccttgctt ggacagttgt
    68461 ttcagttctg tttttcaata ccgtcttgag aaatgtgaca gatatcaagt tatggggcat
    68521 ttggtttctt tttattctgc tagctattgg tatgaattgg ttaacttatt cctgtttcaa
    68581 agaaatgttt cgcttgagac aggaactagg gaagtctaag ggtggaaggc attgatttat
    68641 atcggtttct atttgtagga ggtggcttat ggtacctcta aaatcattta ttacacgcta
    68701 ttccaaggtt tatattgata ataatattta atagaacgaa actaaagaaa acaatttaaa
    68761 aaaggaggct tgtgatggaa cacttgttta aaatgataat cttattaccc tgtttttact
    68821 ttttcagctg gattgacaag gataatagag aaagtaaatt tttcccaatt ttttactatt
    68881 tttactggat ttacatcacc ctctattctc tttttagcct tgcttggaca gttttttcag
    68941 ttctgttttt caatatcgtc ttgagaaatt tgacagatat caagttatgg ggtatttggc
    69001 tattattact acttatcgct tttgctagtg actggttaga ctatatctgt ttcaaaaaaa
    69061 tgcttgactt gagacgggaa ctagggaagt ctaaaggcgt aaggcattga tttatactct
    69121 tcgaaaatct cttcaaacca cgtcaacgtc gccttggatt atatatgtaa ctgacttcgt
    69181 cagtcttatc tacaacctca aagcagtgct ttgagcaact tgcggctagt ttcctagttt
    69241 gctctttgat tttcattgag tattatatta ctttctattt gtaggaggtt gcttatgaag
    69301 attcctctct taactttggc aaggcataaa tttgtttatg tcttgcttac tttgcttttt
    69361 cttgctttgg tttatcgtga tgttttgatg acttatttct tttttgatat tcatgcgccc
    69421 gatctagcta aattcgatgg acaagcaatt aaaaatgact tattaaaatc agcattagat
    69481 tttcgtattc tccagttcaa tctaggtttt tatcaatcat ttattattcc aatcatcatt
    69541 gttttgctag gttttcaata tattgagctg aaaaataaag ttttacgatt gagtattgga
    69601 agagaagtga gttatcaagg gttaaaaaga aagttgactt tgcaagttgc aagtatccct
    69661 tgtttgatat atttagtgac tgtgctgata attgcaattg taacctattt ctttgggact
    69721 ttttctcctc ttggatggaa ttctctattt tctgatggga gtagtttaca aaggctccta
    69781 gatggagaga taacaagcta tttgttcttt acttgtgtcc tactaatcgg tattttcatc
    69841 aatgcagtct atttttttaa aatagttgat tatttaggaa atgtgactcg ttcggcaatc
    69901 acctatttga tgtttctttg gcttggttct atgctgctct atagtgcctt gccttactat
    69961 atggttccta tgacgagttt gatgcaagct agctatgggg atgtaagttt gatgaaactc
    70021 tttactcctt atatccttta tattgtccct tacatggtgc ttgaaaaata tgaagataat
    70081 gtttaagaat tttaacaata ttttgctaaa gagaaagatt gttttactac ttcgtatagt
    70141 tctgatgatg attttgataa accatctatt gtcaacagcg gttcaaaagc aggatgctgt
    70201 tatctttttc aagagagaat tgatttcaat tttttcctat aatgactatt ctgaagtgaa
    70261 tttagaaatc cccaaactct tgttaaacct ttcgcttttc atggtaggat ggctctctgt
    70321 cattttactt gaaagtgatt tggcagacca ttaccatcac ttgattcgct atcaatcaag
    70381 ctcctttttc gattatacaa ggaaacgatt ggttgtcatt tctaaatttt ttactcaaga
    70441 tttacttgtc tggttccttg gtttacttcc gctaggaatt catttcaaaa cagtcgcact
    70501 tttcttttta tttgctcagt taatgatgtt gtacttacta ctgtcttatc tgatagcact
    70561 gattagtgcg ggcgctggtt tttccttttt tctctatttt ttagcatttg tgggacaaga
    70621 atggatgatg gatcatattg taacagtgta tttactactc ttaagcttat tagttatgtt
    70681 gattgttagt cgcttggaag agaaatttaa gaaaggataa acgatgaaac ttgaaattat
    70741 aaatggacag aaaatttatg ggaaaagacc tattttaaat cagttgaatt tggtgtttca
    70801 atcaggaaaa atttatggac ttaaaggtga taatggatct ggcaagacgg ttcttttaaa
    70861 ggtacttgct ggttatatta agcttgacaa aggaaaagtt cttcaagatg gtaaagttta
    70921 cgggataaaa aatcattata ttcaggatgc aggaatttta attgaaaaag tcgagttttt
    70981 atctcattta tccctgagag aaaatttgga actgttaagg tatttttcat ctaaagttac
    71041 ggaaaaaaga attgcctatt ggattcaata ctatgattta caggaatttg aagacgttga
    71101 ataccggcat ttatccttgg gaacaaagca aaaaatggcc ttgattcaag cctttatttc
    71161 ctctccttct atactctttc tcgatgaacc tatgaatgct ttggatgaga agagtgtgag
    71221 gttaaccaaa caggtcattt tatcttacct gaaaaaagaa aatggtctgg ttatcctgac
    71281 gtcgcacata tcagaagata tttcagacct ttgtacagat gtattagttg tcgaaaatgg
    71341 acatatacaa tatgtaaagg atatacaatc ctaggagatg gcttatggca catctaaaat
    71401 catttattac acgctattcc aaggtttata ttggtttagt tctgctgatc tggctgtctt
    71461 tcttctttat cccttgggat agagcgattc tgggggtaag gattgacatc ttcatcatac
    71521 agaaagtctt gctagttttt ggaattctgt ccattttgat ggccttgctg tccaagaaag
    71581 tcagtctctt tgtttttgga ctgatttgct gtctttctct ttggattaac ttatttatca
    71641 catttgccat tttgccaatt tttggcaatt aaacagtcat aaaagtcgga gaggttagct
    71701 tgaaaactaa cctctttttc cttttcaaaa tggggattct tccttgaaaa taatcagtaa
    71761 ttgtgctaaa attaaaggaa cattctaaaa tattcggaat ttaaagtaag gaaaaacatg
    71821 gctaatattt taaaaacaat tatcgaaaat gataaaggag aaatccgtcg tctggaaaag
    71881 atggctgaca aggttttcaa atacgaagac caaatggctg ctttgactga cgaccaacta
    71941 aaagcaaaaa cagttgaatt taaggaacgt tatcaaaatg gagaatcact ggattcattg
    72001 ctttacgaag catttgcggt tgtccgtgaa ggtgccaaac gtgtcctagg tctcttccct
    72061 tataaggttc aggtcatggg ggggattgtt cttcaccatg gtgacgtgcc agagatgcgt
    72121 acaggggaag ggaaaacctt gactgcgacc atgccggtat acctcaatgc cctttcaggt
    72181 aaaggggttc acgtagttac ggttaatgaa tacctgtcag aacgtgacgc gactgagatg
    72241 ggtgaattgt actcttggct tggtttgtca gtagggatta acttggctac caaatctcca
    72301 atggagaaaa aagaagccta tgagtgtgat attacttact caactaactc agaaatcgga
    72361 tttgactacc ttcgtgacaa tatggtcgtt cgcgctgaaa acatggtaca acgtccgctt
    72421 aactatgcct tggtcgatga ggttgactct atcttgattg acgaggctcg tacacctttg
    72481 attgtatcag gtgccaatgc ggttgaaacc agtcagttgt atcacatggc agaccactat
    72541 gtaaaatctt tgaacaaaga tgactacatc atcgatgtgc agtctaagac tattggtttg
    72601 tctgattcag ggattgacag ggctgaaagc tacttcaaac ttgaaaacct ctatgacatc
    72661 gaaaacgtgg ctttgaccca ctttatcgat aacgcccttc gtgccaacta catcatgctt
    72721 ctcgatattg actatgtggt gagcgaagag caagaaatct tgattgtcga ccaatttaca
    72781 ggtcgtacca tggaaggtcg tcgttattct gatggattgc accaagctat tgaagccaaa
    72841 gaaggtgtgc caatccagga tgaaaccaag acatctgcct caatcacgta ccaaaacctt
    72901 ttccgtatgt acaaaaaatt gtctggtatg acgggtacag gtaagactga ggaagaagaa
    72961 tttcgtgaaa tctacaacat tcgtgttatt ccaatcccaa caaaccgtcc tgttcaacgt
    73021 attgaccact cagaccttct ttatgcaagt atcgaatcta agtttaaagc ggttgtcgaa
    73081 gacgttaagg ctcgttacca aaagggtcaa cctgtcttgg ttggtacagt agcggttgaa
    73141 actagtgact acatttctaa gaaattggtc gcagctggtg ttcctcacga agtcttgaat
    73201 gccaaaaacc actatagaga agcccaaatc atcatgaatg ctggtcaacg tggtgccgtt
    73261 accatcgcaa ccaacatggc gggtcgtggt accgacatca agcttggtga aggtgttcgt
    73321 gaacttggag gactttgtgt tattggtaca gaacgtcatg aaagtcgtcg tatcgataac
    73381 cagcttcgtg gacgttcagg tcgtcaagga gatccaggtg agtcacaatt ctacctatct
    73441 cttgaagatg atttgatgaa acgttttggt tctgaacgct tgaagggaat ctttgaacgc
    73501 ttgaacatgt ctgaagaggc gattgagtct cgcatgttga cgcgtcaggt tgaagcagct
    73561 cagaaacgtg tcgaaggaaa taactacgat acccgtaaac aagtccttca atacgatgat
    73621 gtcatgcgtg aacaacgtga gattatctat gctcaacgtt acgatgtcat cactgcagat
    73681 cgtgacttgg cacctgaaat tcagtctatg attaagcgca cgattgaacg tgtcgttgat
    73741 ggtcatgcgc gtgccaaaca agatgaaaaa ctagaggcaa ttttgaactt tgctaagtac
    73801 aacttgcttc ctgaagattc tattacgatg gaagacttgt caggcttgtc tgataaggcc
    73861 atcaaggaag agcttttcca acgtgccttg aaggtttacg atagtcaggt ttcaaaacta
    73921 cgcgatgaag aagcagttaa agaattccaa aaagttttga ttctacgagt ggtggataac
    73981 aagtggacag atcatatcga tgcccttgat caattgcgta acgcggttgg acttcgtggc
    74041 tatgctcaga acaaccctgt tgttgagtat caggcagaag gtttccgtat gtttaatgat
    74101 atgattggtt cgattgagtt tgatgtgaca cgcttgatga tgaaagcaca aattcatgaa
    74161 caagaaagac cacaggcaga acgtcatatc agtacaacag cgactcgcaa tatcgctgct
    74221 caccaagcaa gtatgccaga agatttggat ttgagccaga ttggacgcaa tgaactttgc
    74281 ccatgtggtt ctggtaagaa atttaaaaac tgtcacggta aaagaaaata aaatgagata
    74341 gtttagaggc ggatatcttg tgaaaagtaa atttttactg ggtatccgtt tgctttataa
    74401 ggagatgagt tatggtattt acagcaaaaa gctctaaaat aaatatagaa gaagttcgtg
    74461 ccttgtcaaa attagaaggt caggctttgg agaggaaatc acagcgagat caagagctag
    74521 aagccattat acgtggagaa gaccagcgaa ttctcttggt aatcgggcca tgctcatctg
    74581 acaacgaaga agctgtcctt gaatacgcta agcgtttggc agtcctacaa gaagaagtgg
    74641 cagatcgtat ctttatggtt atgcgtgttt atactgccaa accccgtacc aacggagatg
    74701 gctataaggg cttgattcac cagcctaacg cgacagaagc gcctagtctt atcaatggaa
    74761 tcaaagccgt tcgccatctt cactatcgtg tcatcacaga aacagggatg acaactgctg
    74821 atgaaatgct ttatcctgaa aaccttccgc ttgtagatga tttgatttct tacatggcag
    74881 ttggtgcccg ttcagttgaa gaccagcaac accgctttgt ggcaagtggg gcaggatttt
    74941 ctactggttt taaaaatcca acctctggaa atctcaatgt catgtttaat gggatttatg
    75001 ctgctcaaaa caaacaaagt ttccttttct taggaaaaga agtagaaaca actgggaacc
    75061 cgctttcaca cgctattctt cgtggtgctc ttaatgagta tggaaaaaat attcccaact
    75121 actattatga caatttaatt gataccattg cccagtatga gaaaatgggc ttggaaaatc
    75181 cttttatcat cattgatacc aatcatgaca attctggtaa gcagtatatt gaacagatcc
    75241 gaattgtccg ccagaccttg attaaccgtg cttggaatga aaaaattaag cagttcgttc
    75301 gtggttttat gattgagtct tatctggaag atggtcgaca aaatgagcca gaagtatttg
    75361 gtaagtctat cacagaccct tgcctgggtt gggataacac agaagctctt gtcagagaaa
    75421 tttacaaaac gttaggagaa taagatggca tttattgaaa aaggtcaaga aatcgatatg
    75481 gaagtcatta aggctgaaac ccaattgtct gcggaagcct tgagactcaa ggaaagccgt
    75541 gacagggaat tggcagatat tatttcaggg gaagatgacc gtattctctt ggtgattggt
    75601 ccttgctctt ctgataatga agaggcggtc ttggaatatg ctcgccgttt atccgccttg
    75661 caaaagaagg tagcggacaa gattttcatg gtcatgcgcg tgtatactgc taagcctcgt
    75721 accaatggag acggctataa aggattagtt caccagccag atacttctaa ggctccaagc
    75781 ctgattaatg gcttgcaggc tgtgcgccag ttgcactacc gcgtgattac agagactggt
    75841 ttgacaacgg cagatgagat gctttatccg tcaaatctga tcttggtgga tgacttggtc
    75901 agctaccatg ccgttggagc tcgttctgtg gaagaccaag agcaccgctt tgtggcttct
    75961 gggattgatg caccagtagg gatgaaaaat ccaacctcag gaaatttggg tgttatgttt
    76021 aacgccatct atgctgctca aaacaagcaa accttccttt atcatgggca ggaagttgag
    76081 acatcaggta atcctttggc ccatgttatc ctccgtggag cagtcaacga gtatggcaat
    76141 tatatgccga attactacta tgaaaatcta ctccaagcca ttgaacgcta tgaaaccatg
    76201 ggacttgaaa atccttttat cctcattgac accaaccatg ataactcagg caagcaatat
    76261 atggagcaga ttcgaattgt tcgccagacc ttgcagaatc gtgattggaa tgagaaaatt
    76321 aaaaagacgg ttcgaggatt tatgattgaa tcttacctag cagatggtcg tcaaaaccaa
    76381 ccagagatct ttggttgctc tattactgac ccttgcctag gttgggaaaa tacagaggcc
    76441 ttggtagaag agatttatgt taccttgaca aaataagtga aaaggatgga gttggggaat
    76501 ctcaactcct tttgatgaga atgatagttg gacacggaat tgacatcgaa gaattggctt
    76561 cgatagaaag cgcagttaca cgacatgaag gatttgctaa gcgtgtactg accgctcagg
    76621 aaatggagcg cttcaccagt ctcaaaggac gcaggcaaat agaatattta gctggtcgct
    76681 ggtcggctaa ggaggccttt tccaaggcta tgggaacggg cattagcaag ctcggttttc
    76741 aggatttgga agtcttgaac aatgaacgtg gggcgcctta ttttagtcag gcaccatttt
    76801 caggaaagat ttggctgtct atcagccaca ccgatcagtt tgtgacagcc agtgtcattt
    76861 tggaggaaaa tcatgaaagc tagtccacat agaccaacca aggctctgat tcatctggga
    76921 gctattcgac aaaatattca gcaaatgggg gctcatatcc ctcaaggaac gctcaagttg
    76981 gctgtggtta aggccaatgc ttatggtcat ggagctgttg ccgttgccaa ggcaattcaa
    77041 gatgatgttg atggcttttg cgtttccaat atcgatgaag ccattgaact cagacaagct
    77101 ggactcagca agccaatcct cattttagga gtttctgaaa tcgaagctgt tgctctagct
    77161 aaagaatatg acttcacctt gacagtggct ggactggagt ggattcaagc actcttagat
    77221 aaggaagtgg acctaactgg attgacagtc cacctcaaga ttgattcagg gatgggacgg
    77281 attggtttta gagaggcaag tgaggttgag caggctcaag atttgctcca acaacacggt
    77341 gtttgtgttg aaggaatctt tacccacttt gctactgctg atgaggaatc agatgactat
    77401 tttaatgccc agttagaacg gtttaaaact attttagcta gtatgaagga agttccagag
    77461 ctggttcatg ctagcaattc tgcaacgact ctttggcatg tagagactat tttcaatgcg
    77521 gttcgtatgg gagatgccat gtatggcctc aatccaagtg gagcggtctt ggatttgcct
    77581 tatgatttga taccggcctt gaccttggag tctgctctgg ttcatgtcaa gacagttcca
    77641 gctggagctt gcatgggcta tggagcaact tatcaagcgg atagcgagca agtcatcgcg
    77701 accgtgccaa tcgggtatgc agatggatgg acaagagaca tgcaaaattt ctctgtcttg
    77761 gtagatggcc aagcttgccc aattgtcggc agggtttcga tggaccaaat cactattcga
    77821 ttgcctaagc tttatccgct aggaaccaag gtaaccttga ttggctccaa tggggataag
    77881 gaaatcactg caactcaggt agcgacctac cgcgtaacca ttaactatga ggtggtttgc
    77941 ctcctcagcg accgtattcc gagagaatat tattagaaaa gaaaggagtg gagcatgaat
    78001 ctacatcaac ccttgcatgt cttgcctggt gtgggaccaa agtcagcaga aaaatacgcc
    78061 aaactaggaa ttgaaaactt gcaagatctc ttgctctact ttcctttccg ttatgaagac
    78121 ttcaaaacca agcaggtgct ggagctggaa gacggtgaga aggcagttct ttctggtcag
    78181 gtagtgactc ctgctagtgt ccagtattat ggtttcaagc gcaatcgcct gcgttttagt
    78241 ctcaagcagg gagaggtcgt ttttgcggtg aatttcttta accagcccta tctggctgat
    78301 aaaatagagt tgggagcaac ccttgctgtc tttggaaaat gggaccgcgc taaggctagt
    78361 ctgactggga tgaaggttct ggctcaggta gaagatgacc tccagcctgt ctatcgtctg
    78421 gctcagggaa tcagtcaggc cagtctggtc aaggtcatca agacggcttt tgatcaggga
    78481 ctggacctct tgatagaaga aaatctgccc cagtctttac tagacaaata caaactcatg
    78541 tcccgttgtc aggcagtccg agctatgcat tttccaaagg atttggcaga atacaagcag
    78601 gctcttcgcc gtataaagtt tgaggaactc ttttatttcc aaatgcagct gcagatgctc
    78661 aagtctgaaa atagagttca gggaagtggt ctggttctga attggtctca ggaaaaagtg
    78721 acagcagtta aagtaagtct tccttttgcc ctgacccaag ctcaggaaaa gagtttgcag
    78781 gaaattttaa ctgatatgaa gtccgaccac cacatgaatc gtctcctaca aggggatgtg
    78841 gggagtggaa aaacggtagt cgctggcttg gccatgtttg cggcagtgac agcaggttat
    78901 caggctgccc taatggtacc aacagaaatc ctcgcagagc aacactttga gagtttacag
    78961 aacctttttc ccaatttgaa actggctctc ttgataggtt ccttgaaagc tgcagaaaag
    79021 agagaggtct tggagaccat tgccaagggt gaggctgatt tgattatcgg aactcacgct
    79081 ctgatacaag atggggtgga gtatgctcgt cttgctttga ttattatcga tgagcagcac
    79141 cgttttggtg tagggcaaag gcgtatttta cgggaaaaag gtgacaatcc agatgtcctc
    79201 atgatgacgg cgactcccat tccacggacg cttgccatca cagcctttgg agatatggat
    79261 gtttccatta tcgaccagat gccagcaggt cggaagccta ttgtgacgcg ctggatcaaa
    79321 catgagcaac tacctcaggt cttgacttgg ttagaggggg aaattcaaaa aggttcccaa
    79381 gcctatgtca tctctccttt gattgaagaa tcagaagctc tagatttgaa aaatgccatt
    79441 gccttatcag aggagttgac gactcatttt gcaggcaagg cagaggtggc tcttctacat
    79501 ggtaggatga agagtgacga aaaagaccag atcatgcagg atttcaagga gagaaagacg
    79561 gatattctgg tttcgacgac ggttattgag gttggggtca acgttcccaa tgcgactgtc
    79621 atgattatca tggatgccga tcgcttcggt ctcagtcaac ttcaccagct tagaggtcgt
    79681 gtcggtcggg gggacaagca gtcctacgct gttctcgttg ctaatcccaa gacggattct
    79741 gggaaagacc gcatgcgtat catgacagaa acgaccaatg gatttgtcct tgcggaggaa
    79801 gatttgaaaa tgcgtggttc tggtgagatt tttggaacca gacagtcagg acttccagag
    79861 ttccaagtgg ctgatattat cgaagatttt ccgattttag aagaagcaag aaaggttgct
    79921 agctacatta gttctataga agcttggcaa gaagatccag agtggcgcat gattgccctt
    79981 catctggaaa agaaagaaca tctggattaa gctttctcta aggaaaactt aagctagttt
    80041 ttaggtttgg ctcttatact aaagtcatca aaaagaaacg aggactctca tatgacagta
    80101 acgattaaag taaattacca aaccactttc caaaagaagg aagcaaaaaa ctagtataaa
    80161 cagaagagag agcgaaatgc tcttttttcg tttctaaaac tactttcagc ccatcatcct
    80221 aaaagtaaag aatctaaatt cactttctat ttacccttct ttcttgcatt gattacatag
    80281 atatgctaca gttgtggtaa cgattacaaa ataaaaggag catgctatga aaaatccagc
    80341 tttgctagaa gaaattaaga cctatagagg aagggatgag gttccggaag actttgatgc
    80401 tttctgggat ggggaagtga aaaatgtttc cacacttcca tcctaccact tggaggaaag
    80461 agatttccac attcctcaag tcaagtgcta tgagttaaca tttgaaggaa gcaaggaagg
    80521 aaaggtctat gcacgcattg ttcttccaaa gagtgaggag aaggttccat taatcttcca
    80581 ttttcatggt tatatgggac gtggctggga ctgggccgac atgctgggct tcaccgtagc
    80641 tggttacggt gttgtttcca tggatgtgcg gggccagtca ggttactcac aagacggctt
    80701 gcgttctcct ttaggaaata ccgtgaaggg gcatattatc cgtggtgcta tggaaggtcg
    80761 ggaccacctc ttttataagg atgtttatct ggatatttac cagttggtcg aaattgttgc
    80821 tagtctgtct caggttgatg agaagcgtct ttctagctat ggtgcctcac aaggaggggc
    80881 tctagctcta gttgcagcag cgctcaatcc tcgaattcag aaaacagttg ccatttatcc
    80941 cttcttgtca gacttcagac gggtgattga gattggtaat actagcgagg cttacgacga
    81001 acttttccgt tatttcaagt ttcacgaccc cttccatgaa acagaggagg aaatcatggc
    81061 gacccttgcc tatatcgatg tcaaaaatct tgcccatcgt atccaaggtg aggttaagat
    81121 gattacgggc ttggacgacg atgtttgcta tcccattacc cagtttgcga tttataatcg
    81181 tctgacctgc gataaaacct atcgcatcat gcctgagtat gctcacgaag ccatgaatgt
    81241 atttgtcaat gaccaagtct acaactggct ctgtggaagt gagattcctt ttaaatatct
    81301 aaaataagga gtcgactcta agcacaaaat cttaaaaatt acaaacacgc atagtatcag
    81361 gggattaaaa aaacttgata ctatgcgttt tatcatggaa atatagtaaa atgaaacaag
    81421 aataggacaa aacgatcagg acagtcaaat cgatttctaa caatgtttta gaagcaaatg
    81481 tgtactattc tagtttcaat ctattatatt tatagaattt tttgttgcta gatttgtcaa
    81541 attgcttaaa ataatttttt tcagaaagca aaagccgata cctatcgagt agggtagttc
    81601 ttgctatcgt caggcttgtc tgtaggtgtt aatacttttc aaaaatctct ttaaaccacg
    81661 tcagcttcgc cttgccgtat atatgtt
//
LOCUS       DAVHSY010000006        70461 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.006, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000006 DAVHSY010000000
VERSION     DAVHSY010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 70461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70461
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.006"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(266..491)
                     /locus_tag="VVR43_000502"
                     /pseudo
     CDS             complement(266..491)
                     /locus_tag="VVR43_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1339..2211
                     /locus_tag="VVR43_000503"
     CDS             1339..2211
                     /locus_tag="VVR43_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU6148908.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2357..2701)
                     /locus_tag="VVR43_000504"
                     /pseudo
     CDS             complement(2357..2701)
                     /locus_tag="VVR43_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            2844..3156
                     /locus_tag="VVR43_000505"
                     /pseudo
     CDS             2844..3156
                     /locus_tag="VVR43_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3160..3876
                     /locus_tag="VVR43_000506"
     CDS             3160..3876
                     /locus_tag="VVR43_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6148909.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(4006..4821)
                     /locus_tag="VVR43_000507"
     CDS             complement(4006..4821)
                     /locus_tag="VVR43_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU6148910.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(4818..5723)
                     /locus_tag="VVR43_000508"
     CDS             complement(4818..5723)
                     /locus_tag="VVR43_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU6148911.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            6135..8264
                     /locus_tag="VVR43_000509"
     CDS             6135..8264
                     /locus_tag="VVR43_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU6148912.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            8251..8700
                     /locus_tag="VVR43_000510"
     CDS             8251..8700
                     /locus_tag="VVR43_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU6148913.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            8759..9031
                     /locus_tag="VVR43_000511"
     CDS             8759..9031
                     /locus_tag="VVR43_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU6148914.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(9385..9576)
                     /locus_tag="VVR43_000512"
     CDS             complement(9385..9576)
                     /locus_tag="VVR43_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148915.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            10004..10762
                     /locus_tag="VVR43_000513"
     CDS             10004..10762
                     /locus_tag="VVR43_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6148916.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            10764..12752
                     /locus_tag="VVR43_000514"
     CDS             10764..12752
                     /locus_tag="VVR43_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6148917.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(12795..13373)
                     /locus_tag="VVR43_000515"
     CDS             complement(12795..13373)
                     /locus_tag="VVR43_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003070359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT1/CCC1 transporter family protein"
                     /protein_id="HEU6148918.1"
                     /translation="MDSNFAGRLNILRAGVLDANDGIISIAGGEYVSVSTPKDTEEAA
                     VSREKLLLDQDRELAKKSLYASYIQNGEFKTSAQLLTNKIFLKNPLKALVEEKYGIEY
                     EEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYRIPATVLIVGVALLLTGYTSARL
                     GKAPTKTAMIRNLAIGLLTMGVTFLLGQLFSI"
     gene            complement(13369..14244)
                     /locus_tag="VVR43_000516"
     CDS             complement(13369..14244)
                     /locus_tag="VVR43_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU6148919.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPDKKQASTNFKPAGQSIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRK
                     SRHQIIRLIPNKSAEVVNQALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHP
                     YASWERGTNENHNRLIRRWLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWM
                     ANLNLKFSVRNKSRN"
     gene            14951..16426
                     /locus_tag="VVR43_000517"
     CDS             14951..16426
                     /locus_tag="VVR43_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU6148920.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMAAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(16392..17107)
                     /locus_tag="VVR43_000518"
                     /pseudo
     CDS             complement(16392..17107)
                     /locus_tag="VVR43_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            17194..17331
                     /locus_tag="VVR43_000519"
     CDS             17194..17331
                     /locus_tag="VVR43_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148921.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            17362..18222
                     /gene="speE"
                     /locus_tag="VVR43_000520"
     CDS             17362..18222
                     /gene="speE"
                     /locus_tag="VVR43_000520"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU6148922.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            18219..19478
                     /locus_tag="VVR43_000521"
     CDS             18219..19478
                     /locus_tag="VVR43_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU6148923.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVITLIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            19478..20605
                     /gene="nspC"
                     /locus_tag="VVR43_000522"
     CDS             19478..20605
                     /gene="nspC"
                     /locus_tag="VVR43_000522"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU6148924.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEVGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            20602..21687
                     /gene="aguA"
                     /locus_tag="VVR43_000523"
     CDS             20602..21687
                     /gene="aguA"
                     /locus_tag="VVR43_000523"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU6148925.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLYEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEVLEKPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGSAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVAIDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            21697..22572
                     /gene="aguB"
                     /locus_tag="VVR43_000524"
     CDS             21697..22572
                     /gene="aguB"
                     /locus_tag="VVR43_000524"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU6148926.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(22753..23562)
                     /locus_tag="VVR43_000525"
     CDS             complement(22753..23562)
                     /locus_tag="VVR43_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6148927.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWSLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            23834..24055
                     /locus_tag="VVR43_000526"
     CDS             23834..24055
                     /locus_tag="VVR43_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEU6148928.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            24109..24780
                     /locus_tag="VVR43_000527"
     CDS             24109..24780
                     /locus_tag="VVR43_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6148929.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(24832..25029)
                     /locus_tag="VVR43_000528"
     CDS             complement(24832..25029)
                     /locus_tag="VVR43_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6148930.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            25022..25930
                     /locus_tag="VVR43_000529"
     CDS             25022..25930
                     /locus_tag="VVR43_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU6148931.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            25927..26388
                     /locus_tag="VVR43_000530"
     CDS             25927..26388
                     /locus_tag="VVR43_000530"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU6148932.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            26378..27265
                     /locus_tag="VVR43_000531"
     CDS             26378..27265
                     /locus_tag="VVR43_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU6148933.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            27268..29151
                     /gene="cbpE"
                     /locus_tag="VVR43_000532"
                     /gene_synonym="pce"
     CDS             27268..29151
                     /gene="cbpE"
                     /locus_tag="VVR43_000532"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU6148934.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIELYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            29231..30361
                     /locus_tag="VVR43_000533"
     CDS             29231..30361
                     /locus_tag="VVR43_000533"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU6148935.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            30371..31633
                     /locus_tag="VVR43_000534"
     CDS             30371..31633
                     /locus_tag="VVR43_000534"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU6148936.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            31637..32434
                     /gene="proC"
                     /locus_tag="VVR43_000535"
     CDS             31637..32434
                     /gene="proC"
                     /locus_tag="VVR43_000535"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU6148937.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            32654..33292
                     /locus_tag="VVR43_000536"
     CDS             32654..33292
                     /locus_tag="VVR43_000536"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU6148938.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKSVLFDGMGLAK"
     gene            33289..34179
                     /locus_tag="VVR43_000537"
     CDS             33289..34179
                     /locus_tag="VVR43_000537"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU6148939.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            34219..34536
                     /gene="yabA"
                     /locus_tag="VVR43_000538"
     CDS             34219..34536
                     /gene="yabA"
                     /locus_tag="VVR43_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU6148940.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            34539..35417
                     /gene="rsmI"
                     /locus_tag="VVR43_000539"
     CDS             34539..35417
                     /gene="rsmI"
                     /locus_tag="VVR43_000539"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU6148941.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     SETSLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQHGMKKNQAIKEVAKYYQWNKS
                     QLYAAYHEWEENQEND"
     gene            35604..36938
                     /gene="trmFO"
                     /locus_tag="VVR43_000540"
     CDS             35604..36938
                     /gene="trmFO"
                     /locus_tag="VVR43_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU6148942.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            37022..37759
                     /locus_tag="VVR43_000541"
     CDS             37022..37759
                     /locus_tag="VVR43_000541"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU6148943.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            37768..38325
                     /gene="frr"
                     /locus_tag="VVR43_000542"
     CDS             37768..38325
                     /gene="frr"
                     /locus_tag="VVR43_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU6148944.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            38385..39239
                     /gene="cvfB"
                     /locus_tag="VVR43_000543"
     CDS             38385..39239
                     /gene="cvfB"
                     /locus_tag="VVR43_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU6148945.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDLTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            39248..39463
                     /locus_tag="VVR43_000544"
     CDS             39248..39463
                     /locus_tag="VVR43_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU6148946.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDAIWQEYLEH"
     gene            39549..40517
                     /locus_tag="VVR43_000545"
     CDS             39549..40517
                     /locus_tag="VVR43_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU6148947.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEETACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(40495..40674)
                     /locus_tag="VVR43_000546"
     CDS             complement(40495..40674)
                     /locus_tag="VVR43_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148948.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            40710..41210
                     /locus_tag="VVR43_000547"
     CDS             40710..41210
                     /locus_tag="VVR43_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6148949.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNCRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            41213..41473
                     /locus_tag="VVR43_000548"
                     /pseudo
     CDS             41213..41473
                     /locus_tag="VVR43_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(41840..42166)
                     /locus_tag="VVR43_000549"
     CDS             complement(41840..42166)
                     /locus_tag="VVR43_000549"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148950.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(42112..42525)
                     /locus_tag="VVR43_000550"
     CDS             complement(42112..42525)
                     /locus_tag="VVR43_000550"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEU6148951.1"
                     /translation="MGAHFLTKQAGGSGVLPGGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASVRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            complement(42526..42951)
                     /locus_tag="VVR43_000551"
     CDS             complement(42526..42951)
                     /locus_tag="VVR43_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEU6148952.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVADRMAV"
     gene            43128..43697
                     /locus_tag="VVR43_000552"
     CDS             43128..43697
                     /locus_tag="VVR43_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6148953.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            43765..44415
                     /locus_tag="VVR43_000553"
     CDS             43765..44415
                     /locus_tag="VVR43_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEU6148954.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEEEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            44399..46639
                     /locus_tag="VVR43_000554"
     CDS             44399..46639
                     /locus_tag="VVR43_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU6148955.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKKIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GYLNTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLIGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     LEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGWNSW
                     KIESVR"
     gene            46781..47005
                     /locus_tag="VVR43_000555"
     CDS             46781..47005
                     /locus_tag="VVR43_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148956.1"
                     /translation="MIIGLFQSSISAVTATKSYKYDWNTVLEYSINYHDHQYAWIPEW
                     SRYYSYSEYKVGGGWNYARYEVINYYSGGY"
     gene            47038..47625
                     /locus_tag="VVR43_000556"
     CDS             47038..47625
                     /locus_tag="VVR43_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6148957.1"
                     /translation="MLQLTHVTLKTRQVILQDADFTFKKGRFYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            47629..48810
                     /locus_tag="VVR43_000557"
     CDS             47629..48810
                     /locus_tag="VVR43_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148958.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     misc_feature    48970..49101
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            49117..49647
                     /gene="infC"
                     /locus_tag="VVR43_000558"
     CDS             49117..49647
                     /gene="infC"
                     /locus_tag="VVR43_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU6148959.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            49680..49880
                     /gene="rpmI"
                     /locus_tag="VVR43_000559"
     CDS             49680..49880
                     /gene="rpmI"
                     /locus_tag="VVR43_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU6148960.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            49932..50291
                     /gene="rplT"
                     /locus_tag="VVR43_000560"
     CDS             49932..50291
                     /gene="rplT"
                     /locus_tag="VVR43_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU6148961.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            50349..50729
                     /locus_tag="VVR43_000561"
     CDS             50349..50729
                     /locus_tag="VVR43_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6148962.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            50979..51779
                     /locus_tag="VVR43_000562"
     CDS             50979..51779
                     /locus_tag="VVR43_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU6148963.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            51790..52728
                     /locus_tag="VVR43_000563"
     CDS             51790..52728
                     /locus_tag="VVR43_000563"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU6148964.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            52770..54935
                     /gene="lytB"
                     /locus_tag="VVR43_000564"
     CDS             52770..54935
                     /gene="lytB"
                     /locus_tag="VVR43_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEU6148965.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYNSHSQAWYYFKSGGYMTANEWIWDKESWFY
                     LKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNENAA
                     YYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQ
                     ALDASKDFIPYYESDGHRFYHYVAQNASIPVAFHLSDMEVGKKYYSADGLHFDGFKLE
                     NPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHS
                     ALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGR
                     TFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(54996..56651)
                     /gene="pavA"
                     /locus_tag="VVR43_000565"
     CDS             complement(54996..56651)
                     /gene="pavA"
                     /locus_tag="VVR43_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU6148966.1"
                     /translation="MSFDGFFLHHIVEELRNELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDQAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            56756..57253
                     /gene="ybeY"
                     /locus_tag="VVR43_000566"
     CDS             56756..57253
                     /gene="ybeY"
                     /locus_tag="VVR43_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU6148967.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            57234..57629
                     /locus_tag="VVR43_000567"
     CDS             57234..57629
                     /locus_tag="VVR43_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU6148968.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENMVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            57646..58545
                     /gene="era"
                     /locus_tag="VVR43_000568"
     CDS             57646..58545
                     /gene="era"
                     /locus_tag="VVR43_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU6148969.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            58594..59418
                     /gene="mutM"
                     /locus_tag="VVR43_000569"
     CDS             58594..59418
                     /gene="mutM"
                     /locus_tag="VVR43_000569"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU6148970.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            59418..60023
                     /locus_tag="VVR43_000570"
     CDS             59418..60023
                     /locus_tag="VVR43_000570"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU6148971.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKSGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDTQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            60010..61209
                     /locus_tag="VVR43_000571"
     CDS             60010..61209
                     /locus_tag="VVR43_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEU6148972.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEVFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            61209..61358
                     /gene="rpmG"
                     /locus_tag="VVR43_000572"
     CDS             61209..61358
                     /gene="rpmG"
                     /locus_tag="VVR43_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU6148973.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            61398..61631
                     /gene="secG"
                     /locus_tag="VVR43_000573"
     CDS             61398..61631
                     /gene="secG"
                     /locus_tag="VVR43_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU6148974.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            61733..64087
                     /gene="rnr"
                     /locus_tag="VVR43_000574"
     CDS             61733..64087
                     /gene="rnr"
                     /locus_tag="VVR43_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU6148975.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            64050..64517
                     /gene="smpB"
                     /locus_tag="VVR43_000575"
     CDS             64050..64517
                     /gene="smpB"
                     /locus_tag="VVR43_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU6148976.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            64533..65393
                     /gene="tehB"
                     /locus_tag="VVR43_000576"
     CDS             64533..65393
                     /gene="tehB"
                     /locus_tag="VVR43_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU6148977.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTKPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDIPVDLYDINSASIGQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            65466..66419
                     /gene="coiA"
                     /locus_tag="VVR43_000577"
     CDS             65466..66419
                     /gene="coiA"
                     /locus_tag="VVR43_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU6148978.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            66438..68249
                     /gene="pepF"
                     /locus_tag="VVR43_000578"
     CDS             66438..68249
                     /gene="pepF"
                     /locus_tag="VVR43_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU6148979.1"
                     /translation="MVLQRNERNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVA
                     QYEGHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLY
                     SQLDQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELL
                     AGAGEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAY
                     QALYATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAA
                     VRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGE
                     DYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETG
                     HSMHSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLD
                     GFRGTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQY
                     EWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVM
                     RKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            68251..68964
                     /locus_tag="VVR43_000579"
     CDS             68251..68964
                     /locus_tag="VVR43_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU6148980.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFYATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            69031..69972
                     /gene="prsA"
                     /locus_tag="VVR43_000580"
     CDS             69031..69972
                     /gene="prsA"
                     /locus_tag="VVR43_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU6148981.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(70089..70430)
                     /locus_tag="VVR43_000581"
                     /pseudo
     CDS             complement(70089..70430)
                     /locus_tag="VVR43_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        21094 a        13008 c        15756 g        20603 t
ORIGIN      
        1 attcttctca gctagtgtac taaggagtgt gtgcctgaaa atatgggaac taaggggctg
       61 gtttatcggt ttctctagtt tagtatttgc cttttgcaaa gtgatcttaa atgcctttct
      121 ctaaatttac atatcactat tgtttaacaa aatctaatct attttaggtc acttattctt
      181 tttttgaaat gtagaatgaa ctttttcaaa gtttttcgaa tcttttaaaa tctgtttgtt
      241 ttatatcgcc attctccccc cttttttaat tctccctata tagcctgaca actttcccga
      301 tggtacgaat atggttgctt tcgtctaggt ggatgtcggg gtattcggga ttgagttttt
      361 ttgaggtagc cttggcggag tttcttgaca tagttagcgc cgtctacttg gaagatgccg
      421 atggtattat agtcaatctg tggggtattc ttgataaata ggtagtcgct gtttcttatc
      481 tttgcctcca tggacttgct gacgacataa gcgattgggt cgtagtcgtc tgggataatg
      541 gaaactccat aactaaatcg tcgtcctgca tcgagcggct acctgcagag ataaactacc
      601 taacacgaga gtaagtagtc tgtctgtagt cgtccagtct gatgattttt acgatccttc
      661 gtttttctgc ttatacagtt gcctctcggc ataggttagg actttacctt gtctgggtgg
      721 tgcccgttgg tcgtagatag attggatatc gctaggagaa tccttttgaa ctggaggaaa
      781 gagggcatca atcaagctac tgaatacttt aactaagtca aatatagtat ttttcttagt
      841 agacctaacc cttttttcat aatttctaat ggtgttttta cttataccta tcttagtacc
      901 caattcttat tgagtccaac cattactagt ctatattgtt ttatagttga ttgagtttgg
      961 aatagtacgc tgtagctgct aaaacatttc taggaattaa tttgcctttc ctaatagagt
     1021 tgttcatatc ttatttcaat ctattatatt tttcgcctct aacaatcgca atctcttctt
     1081 tatctacgaa cgaaatcgct ttctattttt gtaagtaaag catcacacga aatccacgaa
     1141 aatgaaaacc tttgttgtgt tttcgtaaaa aatttgttga cagagcacga aacgcctact
     1201 ataattaaat caagtttaag gaaataacaa aaaaacaaat cggagggaaa gacgatgaac
     1261 acattaaatg agaaagtaat caatatctgt aaagcagtag ttaaagaaac tttaatccaa
     1321 gacatttagg agaaagaaat gaagaaatca agaaaattag ccacattagg aatctgttca
     1381 gccttgtttt taggcttggc tgcttgtcaa caacaacatg ctacttctga gggtacgaat
     1441 caaaggcaaa gcagttcagc gaaagttcca tggaaagctt catacaccaa cctaaacaac
     1501 caggtaagta cagaagaggt caaatctctc ttatcagctc acttggatcc aaatagtgtt
     1561 gatgcatttt ttaatctcgt taatgactat aataccattg tcggctcaac tggcttatca
     1621 ggagatttca cttcctttac tcacaccgaa tacgatgttg agaaaatcag tcatctctgg
     1681 aatcaaaaga agggcgattt cgttgggacc aactgccgta tcaatagtta ttgtcttttg
     1741 aaaaattcag tcaccattcc aaagcttgaa aagaatgacc agttgctttt cctagataat
     1801 gatgcgattg ataaaggaaa ggtctttgat tcacaagata aggaagagtt tgatattcta
     1861 ttttcgagag ttccaactga ggcaactaca gatgtcaagg ttcacgctga aaagatggaa
     1921 acattcttct cacaatttca attcaatgaa aaagctcgaa tgctgtctgt agtcttgcac
     1981 gacaatctgg atggcgagta tctgtttgta ggccacgttg gggtcttagt acctgctgat
     2041 gacggtttct tatttgtaga gaaattgact ttcgaagagc cctaccaagc gattaaattt
     2101 gctagtaagg aagattgcta caagtatttg ggcaccaagt atgcggatta tacaggcgag
     2161 ggactggcta agccttttat catggataat gataagtggg ttaaacttta atagtgttat
     2221 gatatgacag taatcttagg atttttattt ctatttttga taagttggtg ggttatttca
     2281 atcgttaata gccagaaacc acgcaaaaat gaaacattta ttggctatgt ccaaagatac
     2341 gatattgatg ggaatggcta tcaatcatta ccgtgtcctc agaactgaga ggagttcttg
     2401 aaatcgtaaa accactttga acaagagtta cttcaaccca ttggctccga cggattaagt
     2461 tgctttcgtg aataccaaaa tcagccgcaa tttgttcata agtgcggtat tctcgcacat
     2521 attgaagagt ggccataaga agatcttcta ggcttaattt aggttttcgt ccaccttttg
     2581 cgtgtttaag ttgataagct gtttttaata cagctaatat ctcttcaaaa gtcgtgcgct
     2641 gaacaccaac aagacgttta aatcgtgcat cagttagttg tttacttgct tcataattca
     2701 tagaactact ataccatatt ttgtttcgca ggaagtctaa tgctaaaatc ttatcagtga
     2761 gaagatttct taaagtttat tctttgtagt ttcatctgta ttagtacata atttaactta
     2821 gagaaaatag gaggactaat cgaatggaat taaaagattt tacagaaaaa gaacaggaaa
     2881 tgattaagaa aaggcttaca atgtctaata ttagtgacaa agaaactact gagaagattc
     2941 tggcgctagt cccacaagac ttgattaagc gaatcccgtt ttttgtcaga aaacatgcta
     3001 caacacgtac gattaaacgc atttcaattg aataccctga actctacgct gtagctcaaa
     3061 caagtggtga gattccagaa aaaaaaacgc gaagaattgc gtcagattat cacaactatc
     3121 tttgaacaaa agatgaataa gcatagtatt aagtagagaa tgaaaaaata ttttattggc
     3181 ggtttgggaa gcaatgccta tcatagcaag gattttcttc aagaactaga ttcgcaggtc
     3241 tattttctaa atccatatga aaagcatctt cgagatgaaa cagaattgaa atcatggttt
     3301 aaaaatgaga ttgtagagga agaatctatc tgtctgatag gtcattctat tggaggcgat
     3361 ttagctcgtt atttcgcatc ggaatttgaa gaagtaaaga aactgattct tttggatggt
     3421 ggctatctag atttagataa gattttacct ttggatacag agttagagga aactaaaaat
     3481 tatatcaaat ctcaaattat ttcggactta gatgttctta cttctaaaga aaaatctgaa
     3541 gcaaagcatt ggtcagaaaa tatggagaaa gctgtaagac agtcctatca ctggaatgtt
     3601 gagtataata gatatgagtt ggctataaat tatgaaaata tagaagcgat actccgccta
     3661 cggagaaaaa tacaagcttt taagagagaa gtgggagata ccttgtttat tagtcctcgc
     3721 tatcctaatg aagctacatg gagagaggaa gccctaaaag aattgccaga ctattttgat
     3781 actatttttt tagaaaactt tggccatgag ctttatactc aagcacctaa agaaatcgct
     3841 agtctaatga atgagtggct cgcttatttt ctatgagcta cttgtattgc tggaaatggt
     3901 ataagatgaa aatctacaag tcactaattt tcatataacc aaaaaacgaa caggctcttt
     3961 ttctgttatt cagaagagaa cttgttcgtt tttatcttga ttttcttaaa aagctctata
     4021 tacataggga ttttctggtt tatcgacttt ggtaaagctg tcgatttcca aggttggaag
     4081 gttttgtttg agttctttat ggtagtgatt gaccagtttt cctttggctg aaatccaagt
     4141 gttgttttca tactgccggg tattgccctt ggtcagcaat ccatagacac cagaatctgc
     4201 gatgcagtga ataatgccga agcggaacag aaattggcta ttagcatgac tggggtcatt
     4261 atagacaaag cctgtgaact ggattgtctt accctcaaat tcatctggat agtcgtagat
     4321 agcctccatg acctccatat agttttcatt agtgatctga atactatctt gggataagta
     4381 tttatccgcc gccgttcgca tttccttttc ataggctgat tttgaaaaat aagaactggt
     4441 atctggtttc aaatattggc ttgtcgtccc ttcgcttgtc tgaatggcta gatccgttcc
     4501 ttccgataga gggaaatgat agcctttagc tgaaacagtc tgagaatcca agctaacagt
     4561 tgggaaagtt aagccgatga caagtggaat agccagaaga gaaatactcg tcatcttggc
     4621 caatcggctg ttcagatgac tgtgggtttt gacttgcttc atccagatat acaattgaac
     4681 gatagccaag ataaaagaaa gcaccatgga gatataggcc agataggaat agtgcatgtt
     4741 gatgtactgg tttagtttgc ccgacagatg gaggtaaata gtcagttcaa aatagccagc
     4801 taaaactaaa aatcgaatca taggatgact ccaatcaaga gagaatagac taagacgaca
     4861 agagttacaa ttgttatgaa gtgactgata aatcgtgctt tcaagtaatt tttcatcatg
     4921 agaatatttt tgatatccag cattggacca atgacgagaa aggccagaac tggtgccaaa
     4981 ccgaaactcg agagaagaga agcacctata aaggcatccg cctcactaca gagcgaaaga
     5041 agaaaggcta aaatcatcaa gagcaggatg gcaaaaagag gggtcgcact gatagaggtc
     5101 agaatccgag tcggaacgta gacctgtatt atagaagcaa agaggcagcc aaataccaaa
     5161 taacgccccg tatcaaaaaa ttcatcaatg gcctgcacaa agacttgaaa aacttttttt
     5221 gcagaactca agtaagaaaa atcatgctca tgacaagcca gacgattttc tttctgaatc
     5281 ggttcttgcc agaaaaatcc tagaaaaatt cctagtatta cagccacaag aatggaaccc
     5341 agagctcgta atagggcgac atggaaggag ttgccaaagg cagaataggt cgcaaaaaga
     5401 acaatgggat tgataacagg tgctgtcaca agaaaaggaa cggccgtgta acttggaacc
     5461 tttttttcca gaaaacgatt gatgatgggg acgattccac attcacaaga agggaaaagt
     5521 ataccgacaa aggtcccaaa aaagattctc ccccaacgat ttcgagggag aaaatgataa
     5581 accttgtcag gtgtgatata aacttcaatc agccctgaga caatgcttcc tatcagaacg
     5641 aagggaaggg cttcaatgat aatggagaga aaaatggctc cagtttgaag tacactagat
     5701 gggagttgtt gaaaagcagt catctagttt ttcttttctg ctttggcttt tttctctttg
     5761 tcatcaggga aagtaacttg tttcaaatca gggagtttag caaactcttc aaacatcttg
     5821 tccaagtcgt ctcgttttgt aaattttaca gccataggtg tacctcgatt ctaaattcta
     5881 cctctattat actattattt tgcggaaaag ggagtttttt aatttgtttt cgatagttga
     5941 tactcttcga aaatctcttc aaaccacgtc agcttcgcct tactgtagta cggttactga
     6001 cttcgtcagt tctatccaca acctcaaaac agtattttga gcagcctacg gctagcttcc
     6061 tagtttgctt tttgattttt attgagtatg aaaaggattg gagaaagcct tccagcttgt
     6121 ggtataatag atttatggat aaaaaatatg aaaaaatctc tcaggatttg ggagtgacgt
     6181 taaagcaaat tgataccgtt ctaagtttga cagctgaagg ggcgactatt ccctttatcg
     6241 cgcgttatcg caaggacatg actggtagtc tggatgaggt ggcgattaag gctattattg
     6301 atttggataa aagtctgaca aatctcaatg accgtaagga agctgtctta gctaagattc
     6361 aagaacaagg taagttgacc aaggaattgg aagaagctat cttagttgcc gaaaaattag
     6421 cagacgttga agaactctat cttccttata aggaaaagcg tcgtaccaag gcaaccattg
     6481 cccgtgaagc tggactcttt cctcttgctc gcttgatttt gcagaatata gttgacttag
     6541 agaaagaagc tgaaaagttc gtctgtgaag gatttgcgac tggcaaggaa gccttgaccg
     6601 gtgcagttga tattttggtc gaagccttat cggaagatgt gaccttgcgt tctatgactt
     6661 atcaggaagt gctgagacac tctaaactca cttctcaagc caaggatgaa agtcttgatg
     6721 aaaagcaggt ttttcagatt tattatgatt tttcagagac agttggaact atgcaaggct
     6781 atcgtacctt ggctctcaat cgtggggaga aacttggtgt cttgaagatc ggttttgaac
     6841 atgcgacgga ccgtattctt gccttctttg ctactcgttt caaggtgaaa aatgcttata
     6901 ttgatgaagt tgttcagcaa tccgttaaga aaaaggtctt gcctgctatt gagcgtcgta
     6961 ttcggacaga attaactgag aaagctgaag agggagctat ccaacttttt tctgacaatc
     7021 tgcgcaatct cctcttggtt gctccactga aagggcgcgt ggttcttggg tttgacccag
     7081 cctttcgtac aggtgccaag ctagctgtcg tggatgcaac aggaaaaatg ctgacaactc
     7141 aggttattta tcctgttaaa ccagcatcag ctcgtcaaat cgaagaagcc aagaaagatt
     7201 tagcagattt aattggtcaa tacggtgtag agattattgc cattggaaat ggaacggcca
     7261 gtcgtgaaag tgaagctttt gtagcggaag ttctgaaaga tttccctgaa gtcagctatg
     7321 ttatcgttaa tgaaagtggt gcttctgtct attctgccag cgaacttgct cgtcaggagt
     7381 ttccagactt gaccgttgaa aaacgctctg ccatttctat cgcccgtcgt ttgcaagatc
     7441 ctcttgcgga attggtcaaa atcgatccta agtcaattgg tgtcggtcaa taccaacacg
     7501 atgtcagtca gaagaaacta tctgagagtc tggactttgt tgtcgataca gtggttaacc
     7561 aagttggtgt caatgtcaat acagctagcc cagctcttct ttcacacgta gctggactca
     7621 ataaaaccat ttctgaaaat atcgtcaaat accgtgagga agagggaaaa atcacttcac
     7681 gctctcaaat caagaaagtt cctcgtttgg gggccaaggc ttttgaacag gctgctggtt
     7741 tcctccgtat ccctgaaagt agcaatatcc ttgataatac aggagttcac ccagaaaatt
     7801 acgctgccgt taaggaactc ttcaaatgct tggacattaa ggatctgaat gaagaggccc
     7861 aaagtaaact caagtcgctt tcagtcaagg aaatggcgca agagttagac cttggtccag
     7921 aaactcttaa agatatcatt gcagatcttc tcaaaccagg tcgagatttc cgtgattcct
     7981 ttgatgctcc agttctccgt caagatgtcc tagatatcaa ggacttagtg gttggacaaa
     8041 agctagaagg agtggtgcgt aatgttgttg atttcggtgc ttttgttgat atcggaattc
     8101 atgaggacgg tctcatccat atttcccata tgagtcgcaa gtttatcaaa caccctagtc
     8161 aagtggtggc agttggagat ttggtgagcg tttgggttaa gaaaattgat actgaacgtg
     8221 aaaaagttaa tctgtctctc ctagctccaa atgaaactga ctgattatgt caagcaggtt
     8281 tcactagaag acttcggcag acctttcatc catcatgtcc agtggaatag gcgtctacgt
     8341 tcgacaggtg ggcgattttt ccccaaagat gggcatctgg attttaatcc caaggtttat
     8401 cagaaactgg gtatggaggt ttttaggaaa attgtccgac atgaactctg tcattatcac
     8461 ctttatttcc aagggaaggg ctatcaacac aaggatcggg attttaagga actgttgaaa
     8521 gcagtggatg gattaaggtt tgtaccatcc ttgcccaata gtaactctaa accactcaag
     8581 ctttatcgtt gtcaatcctg ccagcaaagg tatcagcgca agcgtaggat tgataccaaa
     8641 cgctatcgct gtggactttg tcgaggtaaa ttgcttctga taaatcagcc tgaggactga
     8701 tgaaagccga gcctccccgt gatatactat gtctaaccta gcagaaagag gaaatatcat
     8761 gaacagtaaa ttttataaaa tgagacgcaa tcgcatgatt tcaggagttc tggcaggtct
     8821 gtcagacaag tggaattttg atgttaccct agttcgtttc ttgtttgcca tttttacagt
     8881 tgcaaacttt ggacttggcg tgattatcta tatcatccta gcttctatca tgcctaccaa
     8941 ggaagaaatc gaagcagaaa tgtacggaac aggcccacgt aaacgcaaag aagcccaagc
     9001 cattgacgac aatgaaggct ggttttggtg aggttctaca gaagatttgg aataagcaaa
     9061 aagctttaaa tcaatagtct aaactgcttg atttaaagct tttttacttt tatactcaat
     9121 aaaaatcaaa gtgcaaacta ggaagccagc cacaggctgt aatttagtcg gcaatgtgaa
     9181 gttgacatag tttgcacttt gatttttgaa tagtattaat aatatttcgc cagcttcatc
     9241 cacaaactat agtggattgg aactagaata ggacacctct acttctaaaa cattgttaga
     9301 aatcgatttg actatcctga tcgatttgtc ctgttcttat ttcattttat tataaaagca
     9361 gtaatttaaa ctcagttttt taatctattt ttgctgctga gacaatacat ttttggaaaa
     9421 atggtggatg ctgataacaa ctgataacca gcaaataaca taagcagtgc cggtaaattc
     9481 tgtaccgata aagtgtgtgt gttcaactaa gagctgaccg atgaatggag agagcagata
     9541 gagaagtccg atgagtatat gttctttgtg tttcattaaa gcgcaccttc tttccttata
     9601 ggttgaacga cttgcaagtg ttaaattgaa tggtatgtta tctaggtaac cttactaaaa
     9661 tgttagttcc cgcttcctcc ttttcaaagt aagccttttc acacttatat tttacaactt
     9721 taaaaatagg aaatcaaatc attttctaag taattttgct tatatttcac ccaatcttac
     9781 aaaaatgtaa gattaaagtc tcttttgtaa ggttaggtta tggcaagcga tctttttttg
     9841 atgtaaacta gactcataaa gaacaaagga gtaacatcat gaaacaaatc ttacataaga
     9901 aaactagaaa accaagtcac aaagaaattg agcgcgttca gctgggatgc actatgatgc
     9961 aagctacatt tcatttgatg ggatattaag aaaggagatt ctcatgacac ttttagatgt
    10021 aaaacacgtt caaaaaattt ataaaacacg ttttcagggc aaccaagtag aagccctcaa
    10081 ggatattcac tttaccgtcg aaaagggtga ctacgttgcc atcatgggtg agtctggttc
    10141 tggtaaatca actcttctca atattctagc tatgctggat aaaccaagtc gtggtcaggt
    10201 ttacttgaat ggaactgaca ccgcaaccat taaaaattca caggcctcta gcttccgtcg
    10261 tgaaaagttg ggctttgtct tccaagactt taacttgcta gatactctat ctgtaaagga
    10321 caatatcttg cttccgcttg tcttgtcaag aagacctatt acagagatga tgaagaaatt
    10381 ggtggtgaca gctgagaatc tgggaataaa ccaattacaa gagaagtacc cttacgagat
    10441 ttctggtggc cagaaacagc gtgtagcagt agcacgcgcc atcatcactg aacctgaaat
    10501 tctccttgcg gacgaaccga caggagctct tgactccaag tcatctgcag ccttacttga
    10561 tgtctttgat gaaatcaatg agcgcggcca aaccattctc atggtaaccc actcaacagc
    10621 agcagctagc agagctaaac gtgtactctt tatcaaagac ggcattcttt acaatcaaat
    10681 ctaccgtgga gagaagacag aacgtcagat gttccaagaa atctctgata ccttgactgt
    10741 catggcaagc gaggtgaatt agtatgtttc gattaaccaa taagttagcg gtatcgaact
    10801 tgattaaaaa ccgcaaactc tactatcctt ttgcgctggc tgttctcttg gcagtcactg
    10861 tcacctatct cttttactct ctaaccttca atcctaagat tgcggaaatc cgtggaggaa
    10921 caaccattca ggctacactt ggatttggta tgtttgtcgt cacccttgcg tcagccatta
    10981 tcgttctcta tgccaatagt tttgtcatga agaaccgttc caaggaacta ggaatttatg
    11041 gcatgttggg cttggagaag cgtcatctta tcagtatgac ctttaaggag ttagtggtat
    11101 ttgggattct aactgttgga gcgggtatcg gtattggagc cttgtttgac aagttaattt
    11161 tcgctttcct gctcaaacta atgaaattga aggttgagct ggttgctacc ttccagacga
    11221 aagttgtcat tacagtgctt gttgtcttcg gtttgatttt cctaggcctc atgttcctga
    11281 atgcccttcg aatcgcccgt atgaatgccc tccagctctc tcgtgagaaa gctagtggag
    11341 agaaaaaagg tcgcttcctt cctctccaaa ccattcttgg ttccataagt ttaggaattg
    11401 gctattatct tgcccttacg gtaaaagatc ctcttacagc cttaacaacc ttcttcatag
    11461 ctgttttact ggttatcttt gggacttatc tcttgtttaa tgcagggatt accgttttcc
    11521 tccaaatctt aaagaaaaat aagaaatact attaccaacc aaataacctc atatctgttt
    11581 ctaacttgat tttccgtatg aagaaaaatg cagttggact agctaccatc gctatcttgt
    11641 caacaatggt tttggtaacc atgtcagcag cgacaagcat tttcaattcc tcagaaagct
    11701 ttaaaaaagt tctaaatcct catgattttg gggtttcagg gcaaaatgtt gaaaaagaag
    11761 acttggacaa actcttgagc cagtttgcaa gtgacaaagg ttataagatt aaagaaaaag
    11821 aagtatttcg ttacacttac tttgctgttg cgaatcaaga aggaaccaag ttaactattt
    11881 ttgaaaaagg acaaaaccgt gtccaaccaa aaacagtttt catggtattt gaccaaaaag
    11941 attatgaaaa tatgactggt caaaaactgt ctctatcagg aaatgaggtc ggactctttg
    12001 caaagaatga gggagttaaa gaacagaaag ctctaactct aaatgatcat caattttctg
    12061 taaaagaaga atttactaaa gattttattg tcaaccatgt tccaaatcag tttaatattt
    12121 tgactgctga ttacaattac cttgttgtac ctgatttaca agcctttttg gatcaattcc
    12181 cagattcggc tatctataat cagttttacg gtggtatgaa tgtaaatgcc agtgaagcag
    12241 aacaactcaa ggtcgctgag gagtatgaaa aatacttaca aaagtttaat gctcaattaa
    12301 acactgaagg taactatgtg tatggtagca ctctagcaga tgctagtgct cagatgagtg
    12361 ccctctttgg tggtgtcttc tttatcggta ttttcttatc cattatcttt atggtcggaa
    12421 ccgttctggt catctactac aaacaaattt ctgaaggata tgaagaccgt gagcgcttta
    12481 ttatcttgca gaaagtcggt ttagatcaaa agcaaatcaa gcaaaccatc aacaaacagg
    12541 ttttaactgt attcttcctt cctttgctct ttgccttcct acatctagcc tttgcctacc
    12601 atatgcttag tctgatttta aaagtgattg gtgtactgga tacgactatg atgttgattg
    12661 tgaccttgtc tatctgcgct atcttcctca tcgcctatgt gctgattttc atgattactt
    12721 caagaagtta tcgtaagatt gtccaaatgt aaaaaaagat acctcgactt caaaatcgag
    12781 gtatttcttg ttttctaaat gctgaaaagt tgtccgagca ggaaggtaac tcccatagtt
    12841 aagagaccaa tagcaaggtt ccgaatcata gctgttttgg ttggggcttt tccaagtcta
    12901 gcacttgtgt agccagtgag aagaagggct acaccgacga taaggacggt agcagggatg
    12961 cggtaatcac ttggaaaaat ggtcactgac agcattggag gcaaacttct aaggaaaaag
    13021 gcaacgaagc tagaaatggc agcgtgccaa ggattggtaa attcttcata ctcaatccca
    13081 tatttttcct ctaccagagc cttgagtgga tttttaagaa agatcttatt agtcaagagt
    13141 tgggcagaag ttttgaattc tccattttgg atataagaag catagaggga ttttttggct
    13201 agttccctat cttggtctag caagagtttt tctcgcgaaa cggcagcttc ctcggtatct
    13261 tttggagttg aaacggatac atattctcca ccagcaatgg aaataattcc atcgttagca
    13321 tcaagaacac ccgcacgcag gatatttaaa cgacctgcaa aatttgaatc aatttcgtga
    13381 tttgtttctg acgctaaatt tcaagttcaa gttagccatc cagaagtctt ctctgggtga
    13441 cttgtagtcc aagcattttt taggatagtt gttaatccac ttttcgatga atgcgacttc
    13501 tttgggagtc attttcttgg ttcccttagg taaccatcta cgaatgagcc tgttgtgatt
    13561 ctcattagtt cccctttccc aagaggcata ggggtgcgca taatagatgt gctcctcaga
    13621 aaatacatca aacaagcgat tgaattccgt tccattatct gccgtgatgg aaagaatctt
    13681 gtgttgtttt aagatgagtt ttagagcctg attgaccacc tcagcacttt tatttggaat
    13741 caatcggatg atctgatgtc tactctttcg atccgtcaag acaagcaagc agtagttttt
    13801 cgctctcgta agtagaaccg tatcaatctc ataatgccca ttctccaagc gaagattgat
    13861 agcttcagac cgctgttcga tggattgacc agcaggttta aagttggtgc tagcctgttt
    13921 cttatcaggc gaaaattttt ggttatgata gtggagaatc ttttccttta gttccttggt
    13981 caagcttgat ttcttgaccg agcgcttgcg attgttttca taagactgtt gagcatagtc
    14041 ggcagaataa acctctttga agcgcccttt tccaagacat tgtcggactg tcccacgctt
    14101 gatttcagtg tggatagttt gaggagcttt tccaagtaga gaggcaattt ctctatttga
    14161 tttcccttct tttttccatc tttcgattaa gcgacggcta tcgattgtca aatgtttggc
    14221 ttttgtagta taattgtctt gcatctctgt gcctttcttg tgtttgtggt tgaacaacaa
    14281 gtataacaca gaggtgtttt cttatgccta caagagctat tggctagttg aaccatctaa
    14341 tttttaggag ggctgggtgg ctaacttcat tatagaactt tcatttacga acatatagta
    14401 aaatgaaaca agaacagaac aaatcgatca ggacagtaaa atctatttct aacaatgttt
    14461 tagaagcaga ggtgtactat tctagtttca atctactata tttttatttt ttatcaaaaa
    14521 atactttaca agttcttaaa aacatgatat agtaataaag cttagaaaat gagatgatgt
    14581 tttctagcaa atataaaccc gagtaaaaaa tgcctacgga caggcagggt tgaatgccga
    14641 agcgtggttg aaaagccaca ttattgatag ggttaaaagc ctacttttat aagttgatgt
    14701 taggacactt gttctaattc ataaattttt agtgtggtga aagcacacgt catcttgtga
    14761 aacgatcaat aaagtacgta atatttgcta ctagagagtt aggaaacatc gggaacagac
    14821 atactcaaca gaaaccaaaa taaacacgtc agaagattgc agagcaggtg aaaacctgct
    14881 cttttttcat gagtcaacct ttagttcctt agttttcata aggtcctaaa aatattgaaa
    14941 ggagtatgtt ttgaaagagt tagatcaaaa ccaagcccca atttatgagg ccttggtgaa
    15001 gttacgcaag aaaaggattg ttccctttga tgttccaggt cacaagcgtg gacggggaaa
    15061 tccagaactt gtcgaactct taggagaaaa atgtgtaggc attgatgtca attcgatgaa
    15121 acccttggat aatttaggcc atcctatttc gattattcgt gatgcagagg agctggctgc
    15181 agatgctttt ggagctagcc atgcctttct aatgattggt ggaacaactt catcggtgca
    15241 gactatgatt ctggcaacct gcaaggcagg agataagatt attctgccac gaaatgtcca
    15301 taaatctgct atcaatgcgt tggttctatg tggtgccatt cccatctata tcgagatgag
    15361 tgtagatcct aagattggta tcgctttagg tcttgaaaat gaccgagtag cacaggccat
    15421 aaaggaccat ccagatgcta aggctatcct aatcaacaat cctacttact acggcatctg
    15481 ttcagaccta aaggggttga cagaaatggc tcatgaagct ggcatgatgg ttttagtaga
    15541 tgaagcccat ggagcgcatt tgcatttcac tggtaaactt ccaatttctg ctatggctgc
    15601 aggagctgat atggcagcag tttccatgca taagtctggt gggagtttga cacaaagttc
    15661 gcttctttta atcggggagc agatgaatcc cgagtacgtt cgtcagatta taaacctgac
    15721 ccagtctaca tctgcctctt acttattgat ggctagtttg gatatttcac gtcgcaactt
    15781 ggcccttcgt ggtaaagagt cgtttgagga agtcattgag ctatccgagt acgctcgtca
    15841 tgaaatcaat gccattggcg gttactatgc ttactcaaaa gagttaatag atggtgtgtc
    15901 ggtctgtgat tttgatgtaa ccaagttgtc agtttacact cagggaatag gcttaacagg
    15961 tatcgaggtt tatgacctct tgcgagacga atacgacatt cagattgagt ttggtgatat
    16021 cggcaatatc ttggcctata tttccatcgg cgaccgcatc caagacatcg agcgcttggt
    16081 tggtgctctg gctgatatta agagactcta ttcacgagat gggaaggact taatagctgg
    16141 agaatatatt cagcccgagt tggtgctgtc tccacaagaa gccttctatt cagagagaaa
    16201 aagtttgacc ttagatgagt ctgttggaca ggtctgtgga gaatttgtca tgtgctatcc
    16261 tccagggatt cctatcttgg ctcctggtga acgtattaca cgagaaattg tagactatat
    16321 ccaattcgcc aaggaacgtg gttgctccct ccaagggacg gaagatccag aggtcaatca
    16381 tatcaacgtt attaagagaa agacaaacta taagaaaagt caatagtttt atctaaacta
    16441 tttcttattt caatttgatg atttggcgat gattttagag cacggcaaaa agcccttgaa
    16501 ttagaagcgg tcaatcgctt aatttctatc agcttatcaa atcctgcctc aatccttttc
    16561 tgaggattag ggtagcgtgt caagagttgg taggtatatt ctgaatgctt tccaacgatt
    16621 ttatccaact caggaaagat gatatcaaga caacgagtgt attgtacttt ccaatcagac
    16681 tgtttttctt gagacgatga atatgtctag ccagtatttt taggtctact tgccgattat
    16741 cgtgttgaaa ttgttcacga ttggggtcag aaagaagttt aagagcgatg ccatgagcgt
    16801 ctttcttatc cgttttagtc ttgcgaagtg ataatgattt ggcaaattcc ttgatgagca
    16861 aaggattgta ggtgtaaact ttatatcctt gttcatgcag gaagttcagt agattaaagg
    16921 cataatgtcc agtatcttca agagcgatga gacagtcttg gttgagctgt cgaagagaca
    16981 gatctaagag ttcaaaacca gctttattat ttgaaaaagt gagtggttta agaacagttt
    17041 ttccttgaac attcaaggct gtaacatcgt gtttattttt agcgacatca atgcccacat
    17101 aaagcatggg agtacctcca gatgtagtat ttcaagtcta cttggttatc cacgaacttt
    17161 ttgccttgtt accttagacg agataaaacg tctatgcgtt atcaaactca ttaccaattg
    17221 aaacaaaagc tgtggttaga gcctttcgga aatcgtcaag cgattggagg aaatgaacta
    17281 atccacagtg gcttattcca agtataccac ttgggctttg gcagtagcta actgcgctaa
    17341 atataatata aggagaaata gatggattta tggttttctg aagttcatac tccagatgtc
    17401 aaattgtctc tgagaacagc caagcaactt tacgctggaa aaagtgaatg gcaggatatc
    17461 gaagtcttgg atacgccagc ttttgggaaa atactgattt taaatggcca tgtcttgttc
    17521 tcagatgcgg atgatttcgt ctacaatgaa atgaccgttc acgttcccat ggctgtccac
    17581 ccaaatccaa agaaagtatt ggttattggg ggtggtgacg gcggtgttgc ccaagtatta
    17641 acactctatc ctgaactgga acaaatcgat atcgtggaac cggatgagat gttggtcgag
    17701 gtctgtcgtg agtatttccc agactttgct gcagggctag atgatcctcg tgttaccatt
    17761 tactaccaaa atgggctacg ctttttgcga aactgcgaag atgattacga tattatcatc
    17821 aacgatgcga cagatccatt tggccatacg gaaggactct ttaccaagga attctacggc
    17881 aatagttatc gagctctgaa ggaagacggc atcatgattt accagcatgg gagtcccttc
    17941 tttgacgagg atgagtcggc ctgccgaagc atgcaccgca aggtcaatca agcctttcca
    18001 atcagtcggg tttatcaggc ccatattcca actagcccag ctggctattg gttgtttgga
    18061 tttgcatcga aaaaatacca ccctgtcaaa gattttgaca aggaaggttg gaaaaaacgc
    18121 cagcttttca cagaatacta cactgcaaac ttacacgtgg gagcctttat gttgcccaag
    18181 tatgttgagg acattttaga agaagaggaa ggaaaaaaat gagtcgttta ctagttattg
    18241 gttgtggggg cgttgcccaa gttgctattt caaaaatttg tcaagatagc gaaacattta
    18301 cagagattat gattgctagc cgtaccaagt caaaatgcga tgacttgaaa gcgaagctag
    18361 aaggcaaaac aagtactaaa attgaaactg cagcacttga tgctgacaag gtagaagagg
    18421 tcattacctt gattgaaagc tacaaaccag aagctgtttt gaatgtagct ctgccttatc
    18481 aagatttaac cattatggat gcttgtttgg caacaggtgt tcactatatc gatacagcca
    18541 actacgaagc agaagacaca gaagaccctg agtggcgtgc tatctacgaa aaacgttgta
    18601 aggaacttgg ttttacagcc tactttgact actcatggca gtgggcttat caagagaaat
    18661 tcaaagaagc aggcttgact gctcttcttg gttctggttt tgacccaggt gtaactagtg
    18721 tcttttcagc ttatgccctc aaacactatt ttgatgaaat ccattatatc gacattttag
    18781 actgtaatgg cggtgaccac ggttatccat ttgcaaccaa ctttaatcca gaaattaatc
    18841 tccgtgaggt ttctgcgcca ggttcttact gggaagatgg gaaatgggtc gaagtcgaag
    18901 ctatgtctat caagcgtgag tatgatttcc ctcaagttgg acaaaaagat atgtatctcc
    18961 ttcaccatga agaaatcgaa tcattggcca agaacattcc aggtgtcaaa cgcattcgtt
    19021 tctttatgac ttttggtcaa tcttacttga cgcacatgaa atgtcttgaa aatgttggac
    19081 tccttcgtac ggataccatt aactttaacg gccaagaaat tgttccaatt caatttttga
    19141 aagccttgct tccagatcct gctagccttg gcccacgtac tgtaggtaaa accaatattg
    19201 gatgtatctt tacaggtgtc aaagatggcg ttgaaaagac tatctacatc tacaatgttt
    19261 gcgaccatca agagtgctat gcagaagtcg ggtcacaagc aatttcatac acgacaggcg
    19321 ttccagccat gattgggaca aaattagtca tgaacggaac ttggaaacaa gctggagtgt
    19381 ataaccttga ggagttagat ccagatccat tcatggaagc tttgaatgag tatggtttgc
    19441 catgggttgt ggttgaaaat ccacaaatgg tggactaatg aagttagaac aagtaccaac
    19501 accagcctat gttattgact tggccaagtt agaagctaat tgccgcattc tacaatatgt
    19561 acaagaagag gtcggttgca aggtcttgct tgcccagaag gcatattccc tctacaaaac
    19621 ttatcccttg attagccagt atctatcagg tacgacagct agtggactct atgaggccaa
    19681 attggcaagg gaagaatttc ctggtgaagt ccatgtattt gcgcctgctt tcaaggatgc
    19741 agacttggag gaattgcttg ggataacaga ccatatcgtc tttaactcag agagacagtt
    19801 gcgtaagcat ggggctcgtt gtcgagaggc tggtgtcagt gttggtttgc gcctcaaccc
    19861 tcagtgttca actcaaggag atcacgcgct ctatgaccct tgtgcacctg gttctcgctt
    19921 tggagttact atagacaaga ttccgagtga tttgctagat ttggttgacg gacttcattt
    19981 tcataccctt tgcgagcagg gagcagatga tttacaaaca actttgaaag cagtagaaga
    20041 acagtttggt ccctacttac atgaggtaaa atggctcaat atgggtggtg gtcatcatat
    20101 tacaagagaa ggttacgatg tggatttgct gatttcagaa atcaagcgta tccgaaaaac
    20161 ttacaatctt gaaatctata tcgagcctgg tgaagccatt gcgcttaatg cgggttattt
    20221 agcaactgag gtattagata ttgtagaaaa cggtatggaa atcttggttt tagacgcctc
    20281 tgcgacctgc catatgcctg atgtacttga gatgccctat cgtccacctt tgagaaatgg
    20341 ctttgagtca caggaaaaag cccataccta cagactttct tctaatacct gtctgacggg
    20401 cgatgtgatt ggtgattata gttttgaaaa tccagtccaa atcggagaca gactttattt
    20461 tcaagacatg gccatttatt cttttgtcaa aaataatacc tttaatggta ttggattgcc
    20521 aagtctctat ctcatggacg aacagggaga ctgtagctta ctcaaagctt ttggctatca
    20581 agactttaaa gggagattat catgatggac agtccaaaaa aattaggcta tcacatgcca
    20641 gcagagtacg aaccccatca tggtaccctc atgatatggc cgactcgacc aggatcatgg
    20701 ccttttcaag gaaaggctgc taaaagagca tttactcaga tcatcgagac catagcagaa
    20761 ggggaaagag tctatctttt ggtggagcag gcctatctat atgaagccca atcctatctt
    20821 ggagacaagg ttgtttattt agacattccc accaatgatg cctgggcgcg tgatactggc
    20881 ccaaccattc tcgtcaatga taaaggtaag aaattagccg tggattgggc cttcaatgct
    20941 tggggaggca cctatgatgg tctttatcaa gattatgaag aggatgacca agtagccagt
    21001 cgttttgctg aggtcttgga aaagcctgtc tatgatgcta aaccttttgt actggaagga
    21061 ggcgcaatcc atagcgatgg tcaaggaact attctcgtaa ctgaaagttg cttgcttagt
    21121 cctggtcgca atcctaacct gactaaagag gagattgaaa acacattatt agaaagtctt
    21181 ggtgctgaaa aagttatttg gcttccttat ggtatttatc aggatgaaac caatgaacac
    21241 gtcgataatg ttgctgcctt tgttggttct gctgagcttg ttttggcttg gacagatgac
    21301 gaaaatgatc cccagtatgc catgtcaaaa gcagatctcg aactcttaga acaggaaaca
    21361 gatgcaaaag gttgtcactt caccattcat aaattgccta tccctgcagt tcgacaagtt
    21421 gtgacagaag aagatttgcc aggctacatc tatgaagaag gagaagaaga gcgatacgca
    21481 ggtgaacgac tagcagcttc ctacgtaaac ttttatatcg ccaacaaggc tgtcttggtt
    21541 ccacagtttg aggatgtaaa cgaccaagtg gccatagata tcctcagcaa gtgtttccca
    21601 gaccgtaaag ttgtcggaat accagccaga gatattctct taggtggtgg caatatccac
    21661 tgtatcaccc aacaaattcc agaataggag aaaaagatga gaaatgtaag agttgcaacc
    21721 attcagatgc aatgcgctaa ggatgtggca acaaatatcc aaaccgcaga gcgtttagta
    21781 cgtcaggctg ctgagcaagg agcccaaatt attctcttgc ccgagttgtt tgaacatccc
    21841 tatttctgtc aggaacgtca gtatgactac taccagtatg cccaatctgt agcggaaaat
    21901 actgcaattc agcattttaa ggtgattgct aaggaactac aagttgtttt accaatcagt
    21961 ttctatgaaa aagatggtaa tgtcttgtat aactctattg ccgtcattga tgcagatggg
    22021 gaagtgctgg gcgtttatcg aaagacccac ataccagatg accattatta tcaagaaaaa
    22081 ttctatttca cgcctggtaa cactggtttc aaggtctgga atactcgcta tgctaagatt
    22141 ggtatcggta tctgttggga tcaatggttc cctgaaacag cgcgctgtct tgcattgaat
    22201 ggtgctgaat tgctctttta tcctacagct atcggttcag agccaatttt ggatacagat
    22261 agttgtggtc actggcaacg tactatgcaa gggcacgcag cagcgaatat tgttccagtc
    22321 atcgcagcca atcgttatgg tttagaggag gttactccta gtgaggaaaa tggcggacag
    22381 agttccagtc ttgacttcta cggttcctcc tttatgacgg atgaaacagg agctattcta
    22441 gaacgagctg aaagacaaga agaagctgtt ctgttagcta cttatgacct agacaaggga
    22501 gcaagtgaac gcctaaactg gggcttgttt cgagatagaa gaccagaaat gtatagacaa
    22561 attacagatt agtgtgggag aaatgagaga ttcattctgc tagactaact tcttattagc
    22621 aactataaga tactatggca tctagtaaat cgatttttat gattcgctat tcttgtctat
    22681 tgattagtcc gtattttaaa atattagcaa aaaagcaaat agcagtaact tctgtctatt
    22741 tgcttttctt ttttatagaa tatatttctc aatagcacgc gcaacgccgt cttcttcgtt
    22801 gcttgaggta acggcatccg caagagattt gacataatcg ctggcatttc ccattgcaat
    22861 cccaagccct gcaaactgga gcatttcgat atcgttatta gcatcgccca tggccataat
    22921 ctctgaggaa tcaatcttca aaatctcagc tagtcgtgaa agagcagtag cctttgtcgt
    22981 tccaagcggc attgcttcat aaatgacagg ctgcgaacga actccactga atcgttggca
    23041 aagctcttca gcaaaacgct gctcaaaatc gtctgtttgt tcttttgttc ctaaaaacat
    23101 accttggaac atccggaact ttccactagt cgcttcttca agagaaattt cagtcaggtc
    23161 tgaaaatact agtttagcat cattttcaat aacttgattg ggtttgccac cgagaacaaa
    23221 ataatgtgac tcgtcaaaaa gtgtcaactg aacatcactc ttttcagcaa ggtcatagag
    23281 gtattcgatg tcagctggac tcagttcttt ccagtcaact agactccaat cactggtctg
    23341 gtgagttgaa caaccgttgt taacaataat atattcgttc tggaggtcaa gctccagttt
    23401 tttgtagtag gggaggacac cgaaaagggg gcgacccgta cagagaacca gtttgacacc
    23461 tttttcaatg gctttgtgaa tagcagtaat gtgagcttgt gggatttcct tggcttcatt
    23521 gaggagggtg ccgtccatat ccaaggctag tagtttaatc ataggtcttc cttctttatc
    23581 ttttgctatt attatagcat atttttgaga agaaattgat agaaagcttg agactaattg
    23641 attttatagt ttaagatgtt ttgatgacaa ttcatgattt gaagaggata tttcgcaaag
    23701 atatgctata ctatgtttgt caatgttgca actagacaaa ttaaaaaacc aacttaatat
    23761 aatagttttt ttgtaagtag gtatgagtat cagattactc aactaatctg aagaataatg
    23821 gaggaaatat atcatgattt taatgacaaa aaatataaat ctaacaaatg aagaattaga
    23881 gctgatacaa ggtggagcag atccatatgg taaaaatcct aatggtaggt acgattggga
    23941 aatagaacca gtattaactc tgccggttca tggattttgt cccagaggca cctatgattt
    24001 aggatatatt ggaggaggca atcatctttg caaaggaagt gctgcgagat tttaagtaaa
    24061 atttattagt aatatgaaga aacaagtgga gaaagcagag aatttaatat gaaaaaacgg
    24121 gctattcaaa ttttactagc attgtcctta attttttaca aatcaacttg gttttggaga
    24181 gttttcaatc acctcgcaaa gccctatcta ccagcaagtc gtgaattttt tcagattctg
    24241 cttttgatgg agagcggagt tcttttctta gcggtcatct atctactggt ttttgcagga
    24301 aagaaaattt ttcatttcaa gtggcagctg aggtacttca tctacctttt actgggctac
    24361 atcatttcat atatgtctga cttcctcttt tcgtatttca tatccctgtc ttcaaatcag
    24421 atttctttga atgaaacggt agaaatgatg gggagacagg agttccctta tttcttgctc
    24481 atcgtttgct tcatcgcccc tattgctgag gaattgattt atcgaggtgt gcttatgaca
    24541 acctttttca aaaactcacc ttggtacgga gatgttttgc tttctgctat tattttcggt
    24601 tatattcata tcaattttgc tttaactcct cttgcttttt tcatttatgc tagtggaggt
    24661 cttattttag ctctattgta tcgcatgact aaaaatctct actatccaat actagttcat
    24721 attctcatca atatcactgc cttctgggat gtttggttac tcctattttc aggaagttag
    24781 cttactaaaa aaatgtcgga attttccggc attttctttt ttcacaaata gtcaacgttt
    24841 ttctttccga tactgaagtg gtgtgtagcc acttattttt ttgaattgat tttgaaaata
    24901 agattggcgt gagaaaggca gatagtgaag atagttaaga agaataggat gttctttttt
    24961 cctttttgga aaacttctaa aatatggtat aatgaaaaga taaagaagtt gggggtagaa
    25021 gatgaacatt caacaattac gctatgttgt ggctattgcc aatagtggta cttttcgtga
    25081 agctgctgaa aagatgtatg ttagtcagcc gagtctgtct atttctgttc gtgatttgga
    25141 aaaagagttg ggctttaaga ttttccgtcg gaccagctca gggactttct tgacccgtcg
    25201 tgggatggaa ttttatgaaa aagcgcaaga attggttaaa ggatttgata tttttcaaaa
    25261 tcagtatgcc aatcctgaag aagaaaaaga tgaattttcc gttgctagcc agcactatga
    25321 cttcttacca ccaactatta cggccttttc agagcgctat cctgactata agaacttccg
    25381 tatttttgaa tcaactactg ttcaaatatt agatgaagtg gcgcaagggc atagtgagat
    25441 tgggattatc tacctcaaca atcaaaataa aaaggggatt atgcaacggg ttgaaaagtt
    25501 aggtctggag gtcatcgaat tgattccttt ccatacccat atttatctct gtgagggtca
    25561 tcctttagct cagaaagagg aattagtcat ggaggattta gcggatttac caacggttcg
    25621 tttcactcaa gagaaagacg agtaccttta ttattcagag aactttgtcg ataccagcgc
    25681 tagctcacag atgtttaatg tgacagaccg tgccaccttg aatggtattt tggagcggac
    25741 ggacgcctat gcgacaggtt ctggattttt agatagtgac agtgttaatg gcattacagt
    25801 tattcgtctc aaggataacc tagataaccg catggtctat gttaaacgtg aagaagtgga
    25861 gcttagtcaa gctgggactc tcttcgtaga agtcatgcaa gaatattttg atcaaaagag
    25921 gaaatcatga aaaaaagagc aatagtggca gtcattgtac tgcttttaat tgggctggat
    25981 cagttggtca aatcctatat cgtccagcag attccactgg gtgaagtgcg ctcctggatt
    26041 cccaatttcg ttagcttgac ctacctgcaa aatcgaggtg cagccttttc tatcttacaa
    26101 gatcagcagc tgttattcgc tgtcattact ctggttgtcg tgataggtgc catttggtat
    26161 ttacataaac acatggagga ctcattctgg atggtcttgg gtttgactct aataatcgcg
    26221 ggtggtcttg gaaactttat tgacagggtc agtcagggct ttgttgtgga tatgttccac
    26281 cttgacttta tcaactttgc aattttcaat gtggcagata gctatctgac ggttggagtg
    26341 attattttat tgattgcaat gctaaaagag gaaataaatg gaaattaaaa ttgaaactgg
    26401 tggtctgcgt ttggataagg ctttgtcaga tttgtcagaa ttatcacgta gtctcgcgaa
    26461 tgaacaaatt aaatcaggcc aggtcttggt caatggtcaa gtcaagaaag ctaaatacac
    26521 agtccaagag ggtgatgtcg tcacttacca tgtgccagaa ccagaggtat tagagtatgt
    26581 ggctgaggat cttccgctag aaatagtcta ccaagatgag gatgtggctg tcgttaacaa
    26641 acctcaggga atggttgtgc acccgagtgc tggtcatacc agtggaaccc tagtaaatgc
    26701 cctcatgtat catattaagg acttgtcggg tatcaatggg gttctgcgtc cagggattgt
    26761 tcaccgtatt gataaggata cgtcaggtct tctcatgatt gctaaaaacg atgatgcgca
    26821 tctagcactt gcccaagaac tcaaggataa aaagtctctc cgcaaatatt gggcgattgt
    26881 tcatggaaat ctgcctaatg atcgtggtgt aattgaagcg ccgattggcc ggagtgaaaa
    26941 agaccgtaag aaacaggctg taactgctaa agggaagcct gcagtgacgc gttttcacgt
    27001 cttggaacgc tttggcgatt atagcttagt agagttgcaa ctggagacag ggcgcactca
    27061 tcaaatccgt gtccacatgg cttatatcgg ccattcagtc gctggtgatg aggtctatgg
    27121 tcctcgcaag actttgaaag gacatggaca atttcttcat gccaagactt taggttttac
    27181 tcatccgaga acaggtaaga ccttggaatt taaagcagat atcccagaga tttttaagga
    27241 aaccttggag agattgagaa agtaagaatg aaaaagaaat taactagttt agcacttgta
    27301 ggcgcttttt taggtttgtc atggtatggg aatgttcagg ctcaagaaag ttcaggaaat
    27361 aaaatccact ttatcaatgt tcaagaaggt ggcagtgatg cgattattct tgaaagcaat
    27421 ggacattttg ccatggtgga tacaggagaa gattatgatt tcccagatgg aagtgattct
    27481 cgctatccat ggagagaagg aattgaaacg tcttataagc atgttctaac agaccgtgtc
    27541 tttcgtcgtt tgaaggaatt gggtgtccaa aaacttgatt ttattttggt gacccatacc
    27601 cacagtgatc atattggaaa tgttgatgaa ttactgtcta cctatccagt tgaccgagtc
    27661 tatcttaaaa aatatagtga taatcgtatt actaattctg aacgtctatg ggataatctg
    27721 tacggttatg ataaggtttt acagactgct tcagaaaaag gtgtttcagt tattcaaaat
    27781 atcacacaag gggatgctca ttttcagttt ggggacatgg atattgagct ctataactat
    27841 gaaaatgaaa ccgattcatc gggtgaatta aagaaaattt gggatgacaa ttccaattcc
    27901 ttgattagcg tggtgaaagt caatggcaag aaaatttacc ttgggggcga tttagataat
    27961 gttcatggag cagaagacaa gtatggtcct ctcattggaa aagttgattt gatgaagttt
    28021 aatcatcacc atgataccaa caaatcaaat accaaggatt tcattaaaaa tttgagtccg
    28081 agtttgattg ttcaaacttc ggatagtcta ccttggaaaa atggtgttga tagtgagtat
    28141 gttaattggc tcaaagaacg aggaattgag agaatcaacg cagccagcaa agactatgat
    28201 gcaacagttt ttgatattcg acaagacggt ttagtaaaca tttcaacttc ctacaagccg
    28261 attccaagtt ttcaagctgg ttggcataag agttcatatg gaaactggtg gtatcaagcg
    28321 cctgattcta caggagaata tgctgtcggt tggaatgaaa ttaagggtga atggtattac
    28381 tttaaccaaa cgggtatctt attacagaat caatggaaaa aatggaacaa tcgttggttc
    28441 tatttgacag actctggtgt tgctgctaaa aattggaaga aaatcgctgg aatctggtat
    28501 tattttaaca aagaaaacca gatggaaatt ggttggattc aagataaaga gcagtggtat
    28561 tatttggatg ttgatggctc tatgaagaca ggttggcttc aatataaggg gcaatggtat
    28621 tactttgctc catcagggga aatgaaaacg ggctgggtaa aagataaaga agcctggtac
    28681 tatatggatt ctactggtat catgaagaca ggtgagatag aagttgctgg acatcattac
    28741 tatctagaag aatcaggagc tatgaagcaa ggctggctta aaaaggcaaa tgattggtat
    28801 ttctacaaga cagatggttc acgagctata ggttggatta aagacaagga taaatggtac
    28861 ttcttgaaag aaaatggtca attacttgtg aatggtaaga caccagaagg ctatactgtg
    28921 gattcaagtg gtgcctggtt agtggatgtt ccgatcgaga aatctgctac aattaaaact
    28981 acaagtcatt cagaaataaa agaatccaaa gaagtagtga aaaaggatct tgaaaataaa
    29041 gaaacgagtc aacatgaaag tgttacaaat tcttcaacta gtcaagattt gacatcctca
    29101 acttcacaaa gctctgaaac gagtgtaaac aaatcggaat cagaacagta gtagaaaaga
    29161 aggttttagg gccttctttt tcctatcaac tcttttctat ttcctgttat tcatgttata
    29221 atggataaat atgaataatc ggagtgagac tatgaaatac aaacggattg tctttaaggt
    29281 gggtacttct tctctgacaa atgaggatgg aagtttatca cgtagtaagg taaaggatat
    29341 tacccagcag ttggctatgc tgcacgaggc tggtcatgag ttgattttgg tgtcttcagg
    29401 tgccattgcg gctggttttg gagccttagg atttaaaaag cgtccgacta aaattgctga
    29461 taaacaggct tcagcagcgg tagggcaggg acttttgttg gaagaatata cgaccaatct
    29521 tctcttgcgt caaatcgttt ctgcacaaat cttgctgacc caagatgact ttgtggataa
    29581 gcgtcgttat aaaaatgccc atcaggcttt gtcggttttg ctcaaccgtg gggcaattcc
    29641 tatcatcaat gagaatgata gtgtcgttat tgatgagctc aaggttgggg acaatgacac
    29701 tctaagtgct caagtagcgg cgatggtcca agcagacctt ttagttttct tgacagatgt
    29761 ggacggtctc tatactggaa atcctaattc agatccaaga gccaaacgct tggagagaat
    29821 cgagaccatc aatcgtgaga ttattgatat ggctggtgga gcaggttcgt caaacggaac
    29881 tgggggtatg ttaaccaaaa tcaaggctgc aactatcgcg acggaatcag gagttcctgt
    29941 ttatatctgc tcatccttga aatcagattc catgattgag gcggcagagg agaccgagga
    30001 tggttcttac tttgttgctc aagagaaggg gcttcgtacc cagaaacaat ggcttgcctt
    30061 ctatgctcag agtcaaggtt ctatttgggt tgataaaggg gctgcggaag ctctctctca
    30121 acatggaaag agtcttctct tatctggtat cgttgaagca gaaggagcct tttcttacgg
    30181 tgatatcgtg acagtatttg acaaggaaag tggaaaatca cttggaaaag gacgcgtgca
    30241 atttggagca tctgctttgg aggatatgtt gcgttctcaa aaagccaagg gtgtcttgat
    30301 ttaccgtgac gactggattt ccattactcc tgaaatccaa ctacttttta cagaatttta
    30361 gaggtaaact atggtgagta gacaagaaca atttgaacag gtacaggctg ttaaaaaatc
    30421 gattaacaca gctagtgaag aagtgaaaaa ccaagccttg ctagccatgg ctgatcactt
    30481 agtggctgct actgaggaaa ttttagcggc taatgccctc gatatggcag cggctaaggg
    30541 gaaaatctca gatgtgatgt tggatcgtct ttatttggat gcagatcgta tagaagcgat
    30601 ggcaagagga attcgtgaag tggttgcctt accagatcca atcggtgaag ttttagaaac
    30661 aagtcagctt gaaaatggtt tggttatcac aaaaaaacgt gtagctatgg gtgtcatcgg
    30721 tattatctat gaaagccgtc caaatgtgac gtctgatgcg gctgctttga ctcttaagag
    30781 tggaaatgcg gttgttcttc gtagtggtaa ggatgcctat caaacaaccc atgccattgt
    30841 cacagccttg aagaagggct tggagacgac tactattcat ccaaatgtga ttcaactggt
    30901 ggaggatact agccgtgaaa gtagttatgc tatgatgaag gccaagggct atctagacct
    30961 tctcattcct cgtggaggag ctggcttgat caatgcagtg gttgagaatg cgattgtacc
    31021 tgttatcgag acagggactg ggattgtcca tgtctatgtg gataaggatg cagacgaaga
    31081 caaggcgctg tctatcatca acaatgctaa aaccagtcgt ccttctgttt gtaatgccat
    31141 ggaggttctg ctggttcatg aaaacaaggc agcaagcatc cttcctcgct tggatcaaat
    31201 gctggttgca gatcgaaaag aagctgggtt ggaaccaatt caattccgcc tagatagcaa
    31261 agcaagccag tttgtttcag gtcaagctgc tcaagcacaa gactttgata ccgagttttt
    31321 agactatatt ctagctgtta aggttgtgag cagtttagaa gaagcggttg cgcatattga
    31381 atcccacagt acccatcatt cggatgctat tgtgacggaa aatgctgaag ctgcagcata
    31441 ctttacagat caagtggact ctgcagcggt gtatgttaat gcctcaactc gtttcacaga
    31501 tggaggacaa tttggtcttg gttgtgaaat ggggatttct actcagaaat tgcacgcgcg
    31561 tggtccaatg ggcttgaaag agttgaccag ctacaagtat gtggttgctg gtgatgggca
    31621 gataagggag taagagatga agattggatt tatcggtttg gggaatatgg gtgctagctt
    31681 ggcaaaatct gtcttgcaga ctaggacgtc agatgagatt ctccttgcca atcgtagtca
    31741 agctaaggta gatgctttca ttgcagactt tggtggtcag gcttccagca atgaagaaat
    31801 gtttgcagaa gcagatgtga tttttctagg agttaagcct gctcagtttt ctgaactgct
    31861 ttctcaatat cagaccatcc ttgaaaaaag agaaagtctt cttttgattt cgatggcagc
    31921 tggattgacc ttagaaaaac tagcaagtct tatcccaagc caacaccgaa ttattcgtat
    31981 gatgcctaat acccctgctt ctatcgggca aggagtgatt agttatgcct tgtctcctaa
    32041 ttgcagggct gaggacagtg agatcttttg tcagctttta gccaaggctg gtctcttggt
    32101 tgaattagga gaaagcttaa tcaatgcagc gacaggtctt gcaggttgtg gaccagcctt
    32161 tgtctatctc tttattgagg ccttggcaga tgcaggtgtt cagacgggat taccacgaga
    32221 aacagccttg aaaatggcag cccaaactgt ggtaggagct gggcaattgg tcctagaaag
    32281 ccagcaacat cctggagttt tgaaagatca agtttgtagt ccaggcggtt cgactattgc
    32341 tggcgtagca agcctagaag cgcatgcttt tcgaggcaca gtcatggagg cagttcatca
    32401 agcctataaa cgaacacaag aactaggtaa ataagaggta gctttatctg cctcttttat
    32461 ggtggttgat actcttcgaa aatcaaattc aaactgcgtc agcttcacct tgccgtactc
    32521 aagtacagcc tgcggctagc ttcctagttt gctctttgat tttcattgag tatgaaatga
    32581 gaagacaaaa agattgtcac aaacccctat ttttttgata gaatagaagt agtaaaaaag
    32641 aaatgagtta gacatgtcaa aaggattttt agtctctctt gagggaccag agggagcagg
    32701 caagaccagt gttttagagg ctctgctacc aattttagag gaaaaaggag tagaggtgtt
    32761 gacgacccgt gaacctggcg gagtcttgat tggggagaag attcgggaag tgattttgga
    32821 tccaagtcat actcagatgg atgctaaaac agagctactt ctctatattg ccagtcgcag
    32881 acagcatttg gtggaaaaag ttcttccagc ccttgaagct ggcaagttgg tcatcatgga
    32941 tcgttttatc gatagttctg ttgcctatca gggatttggt cgtggcttag atattgaagc
    33001 cattgactgg ctcaatcagt ttgcgacaga tggcctcaaa cccgatttga cactctattt
    33061 tgacatcgag gtggaagaag ggctggctcg tattgctgct aatagtgacc gcgaggttaa
    33121 tcgtttggat ttggaagggt tggacttgca taaaaaagtt cgtcaaggct acctttctct
    33181 tctggataaa gagggaaatc gcattgtcaa gattgatgct agtctccctt tggagcaagt
    33241 tgtggaaact accaagtctg tcttgtttga cggaatgggc ttggccaaat gaaacaagat
    33301 caactaaagg cttggcaacc agctcagttt gaccgttttg tccgtatctt agaacaagac
    33361 cagctcaatc acgcctatct cttttcaggt ttctttggaa gcttggaaat agcgcaattt
    33421 ttagctaaga gcctcttttg tacggataaa gttggcgtct taccatgtga gaaatgccga
    33481 agttgcaagc tgattgaaca ggaagagttt ccagatgtca ccttgattaa gccagtcaat
    33541 caggtcatca agacagaacg cattcgggaa ttggtgggac agttttctca agcagggatt
    33601 gaaagccagc aacaggtctt tatcatcgag caagcggata aaatgcatcc caacgcagcc
    33661 aattctctgc tcaaggtcat cgaagaaccc cagagtgaag tttatatttt cttcttgact
    33721 agcgatgagg aaaagatgtt accgacaatc cgaagtcgga cccagatctt ccactttaaa
    33781 aagcaagaag aaaaacttat cttactctta gaacaaatgg gacttgttaa gaaaaaagcg
    33841 actcttttag ctaagtttag tcaatcgcga gctgaagcag aaaagttggc taatcaggca
    33901 agtttttgga ccttggtcga tgaaagtgaa cgcctgctga cttggttagt agctaagaaa
    33961 aaagaaagtt atctacaggt tgccaaatta gccaacttgg cagatgataa ggaaaaacag
    34021 gatcaggttt tacggattct tgaagttctc tgtgggcagg acctcttgca ggtaagagta
    34081 agagtgattc tacaagattt actagaagct agaaaaatgt ggcaagctaa tgtcagcttt
    34141 caaaatgcca tggaatatct ggtcttgaaa gaaatataaa ctcaaaaatg aatgataaag
    34201 aaaggaaagg gctgttttat ggacaaaaaa gaattatttg acgcgctgga tgatttttcc
    34261 caacaattat tggtaacctt agccgatgtg gaagccatca agaaaaatct caagagcttg
    34321 gtagaagaaa atacagctct tcgcttggaa aatagtaagt tgcgagaacg cttgggtgag
    34381 gtggaagcag acgctcccgt caaggccaag catgttcgcg aaagtgtccg tcgtatttac
    34441 cgtgatggat ttcacgtatg taatgatttt tatggacaac gtcgagagca ggacgaagaa
    34501 tgtatgttct gtgatgagtt gttatacagg gagtaagcat gcaaattcaa aaaagtttta
    34561 aggggcagtc tccctatggc aagctgtatc tagtggcaac gccgattggc aatctagatg
    34621 atatgacttt tcgtgctatc cagaccttga aagaagtgga ctggattgct gctgaggata
    34681 cgcgcaatac agggcttttg ctcaagcatt ttgacatttc caccaagcag atcagttttc
    34741 atgagcacaa tgccaaggaa aaaattcctg atttgattgg tttcttgaaa gcagggcaaa
    34801 gtattgctca ggtctctgat gccggtttgc ctagcatttc agaccctggt catgatttgg
    34861 ttaaggcagc tattgaggaa gaaattgcag ttgttacagt tccaggtgcc tctgcaggaa
    34921 tttccgcctt gattgccagt ggtttagcgc cgcagccaca tatcttttac ggctttttac
    34981 cgagaaaatc aggccagcaa aagcaatttt tcgactcgaa aaaagactat cctgaaactc
    35041 agatttttta tgaatcgccc catcgtgtgg cagatacatt ggaaaatatg ctagaagtct
    35101 acggtgaccg ctcggtagtc ttggtcaggg aattgactaa aatctatgaa gaataccaaa
    35161 gaggtaccat ttctgaattg ctggaaagca tctctgaaac gtctctcaag ggtgaatgcc
    35221 ttcttattgt tgaaggtgcc agtcaggatg tggaggaaaa agacgaggag gacttgttct
    35281 tagaaatcca agcccgcatc caacatggta tgaagaaaaa tcaagccatt aaggaagttg
    35341 cgaaatacta ccagtggaat aaaagtcagc tttatgctgc ctaccacgaa tgggaagaaa
    35401 atcaagaaaa tgactaaaca gggaagtttg ccttcttccc tttttttgtt atactagtag
    35461 aagaaaaaaa tagaaagatt tgtgggagtg aaaaagtcct gtggactttt tcagcctgag
    35521 ccaagaaact cgaaagctcg taagtctgat tggctttttc aatgtgaatc ttaacttcac
    35581 actcccaaag aggtattagt gtcgtgtctc aatcttatat caatgttatc ggtgctggtt
    35641 tggcaggttc tgaagcagct taccaaatcg cagagcgtgg tattccagtt aaactttatg
    35701 aaatgcgtgg tgtcaagtcg actcctcagc ataaaacaga caattttgct gagttggttt
    35761 gttccaattc tttgcgtggg gatgctttga caaatgcagt tggtcttctc aaggaagaaa
    35821 tgcgtcgctt gggttctgtt atcttggaat ctgctgaggc tacacgtgtt cctgccggtg
    35881 gagcccttgc ggtggatcgt gatggtttct ctcaaatggt gaccgaaaaa gtggtcaacc
    35941 accccttgat tgaagtggtg cgtgatgaaa ttacagaatt gccaacagat gttattacag
    36001 ttgtggcgac tggtcccttg actagcgatg ccctggctga aaagattcat gcccttaata
    36061 atggcgatgg cttctatttc tacgatgcag cagcgcctat tatcgatgtc aacactatcg
    36121 atatgagtaa ggtctatctc aaatctcgtt atgataaggg agaagcagcc tatctcaatg
    36181 ctccaatgac caagcaagag tttatggatt tccatgaagc cttggtcaat gcggaagaag
    36241 caccgctcaa ttcttttgaa aaagaaaagt actttgaagg atgtatgcca atcgaagtta
    36301 tggccaaacg tggcattaaa actatgcttt atggccctat gaagccagtc ggtcttgagt
    36361 atccggacga ctacacagga cctcgtgatg gagaatttaa aacaccttat gcggttgtgc
    36421 aacttcgtca ggataatgca gctggtagcc tatacaatat tgttggtttc cagacccacc
    36481 tcaaatgggg agaacaaaag cgtgtcttcc aaatgattcc gggtcttgaa aatgcggagt
    36541 ttgtccgtta tggtgtcatg catcgcaatt cttacatgga ttcaccaaat cttcttgagc
    36601 agacttaccg ttccaagaaa caaccaaatc tcttctttgc tggtcagatg acgggggtgg
    36661 aaggctatgt tgagtcggcg gcttcgggct tagttgcggg aattaacgca gctcgtctct
    36721 tcaaggaaga aagcgaggtt attttccccg agacgacagc gattggaagc ttagctcatt
    36781 acattaccca tgccgacagc aaacatttcc aaccaatgaa tgtcaatttt gggatcatca
    36841 aggagttgga aggcgagcgt atccgtgata agaaagctcg ttatgaaaaa attgcagagc
    36901 gtgcccttgc cgacttagag gaatttttga ctgtctaatt tttttgaaag aattgttcat
    36961 gatactataa aaatcttaga aattgtgata aaataggtag gatgaaagaa ggagagtgaa
    37021 aatggcgaat cccaagtata aacgtatttt aatcaagtta tcaggtgaag cccttgccgg
    37081 tgaacgtggc gtagggattg atatccaaac agttcaaaca atcgcaaaag agattcaaga
    37141 agttcatagc ttaggtatcg aaattgccct tgttattggt ggaggaaatc tctggcgtgg
    37201 agaacctgca gcagaagcag gtatggaccg tgttcaggca gattacactg gaatgcttgg
    37261 gactgttatg aatgctcttg tgatggcaga ttcattgcaa caagttgggg ttgatacgcg
    37321 tgtacaaaca gctattgcca tgcaacaagt ggcagagcct tatgtccgtg gacgtgccct
    37381 tcgtcacctt gaaaaaggcc gtatcgttat ctttggtgct ggaattggtt caccatactt
    37441 ctcgacagat acaacagcgg cccttcgtgc agctgaaatc gaagcagatg ccatcctcat
    37501 ggctaaaaat ggcgtcgatg gtgtgtacaa tgccgatcct aagaaggaca agacagccgt
    37561 taagtttgaa gaattgaccc accgtgatgt tatcaacaaa ggtcttcgta tcatggactc
    37621 aacagcctca accctctcaa tggacaacga cattgacttg gttgtcttca acatgaacca
    37681 atcaggcaac atcaaacgtg tcgtatttgg tgaaaatatc ggaacaacag tttcaaataa
    37741 tatcgaagaa aaggaataag aaagaatatg gctaacgtaa ttattgaaaa agctaaagag
    37801 agaatgaccc agtctcacca atcacttgct cgtgaatttg gtggtatccg tgctggtcgt
    37861 gccaatgcaa gcttgcttga ccgtgtacat gtagaatact atggagtcga aactcctctt
    37921 aaccaaatcg cttcaattac gattccagaa gcgcgtgttt tgttggtaac accatttgac
    37981 aagtcttcat tgaaagacat cgaacgtgcc ttgaacgctt ctgatcttgg tatcacaccg
    38041 gctaatgacg gttctgtgat tcgcttggtt atcccagctc ttacagaaga aactcgtcgt
    38101 gaccttgcta aagaagtgaa gaaggtcggc gaaaatgcta aagtggctgt ccgcaatatc
    38161 cgtcgcgatg ctatggacga agctaagaaa caagaaaaag caaaagaaat cactgaagac
    38221 gaattgaaga ctcttgaaaa agatattcaa aaagtaacag acgatgctgt taaacacatc
    38281 gacgacatga ctgctaacaa agagaaagaa cttttggaag tctaaaaata aacagaaaaa
    38341 ctcagttggc attgctggct gagttttatt cgaaagaagg aaatatgaat acaaatcttg
    38401 caagttttat cgttggactg atcatcgatg aaaatgaccg tttttacttt gtgcaaaagg
    38461 atggtcaaac ctatgctctt gctaaggaag agggccaaca tacagtaggg gatacggtca
    38521 aaggttttgc atacacggat atgaagcaaa aactccgcct gacaacctta gaagtgactg
    38581 ccactcagga ccaatttggt tggggacgtg tcacagaggt tcgtaaggac ttgggtgtct
    38641 ttgtggatac aggccttcct gacaaggaaa tcgttgtgtc actcgatatt ctccctgagc
    38701 tcaaggaact ctggcctaag aagggcgacc aactctacat ccgtcttgaa gtggataaga
    38761 aagaccgtat ctggggcctc ttggcttatc aagaagactt tcaacgtctc gctcgtcctg
    38821 cttacaacaa catgcagaac caaaactggc cagccattgt ttaccgtctc aagctgtcag
    38881 gaacttttgt ttacctacca gaaaataata tgcttggttt tattcatcct agcgagcgtt
    38941 acgcagagcc acgtttgggg caagtattag atgcgcgcgt tattggtttc cgtgaagtgg
    39001 acctcactct gaacctctcc ctcaaaccac gctcctttga aatgttggaa aacgatgctc
    39061 agatgatttt gacttatttg gaaagcaatg gcggtttcat gaccttaaat gataagtcat
    39121 ctccagacga catcaaggca acctttggca tttctaaagg tcagttcaag aaagctttag
    39181 gtggtcttat gaaggctggt aaaatcaagc aagaccagtt tgggacagag ttgatttagg
    39241 gagatttatg agaaaatcat tttacacttg gctcatgacc gagcgcaatc ctaaaagtaa
    39301 cagtcccaaa gctatcttgg cagacctcgc ttttgaagag gcagcttttc caaaacacac
    39361 agatgatttt gatgaggtca gtcgcttttt ggaggagcat gccagtttct cttttaacct
    39421 aggagacttt gacgctatct ggcaagaata cttagaacac tagcatttat tcactaggtt
    39481 tgggctagta atttctccat ccctctgcta taataaaaag aaataaaagg attagagagg
    39541 ttctttattt gaaggaacat tcaatagaca ttcaactgag tcatccagat gacttgtttc
    39601 atctttttgg ttccaatgaa cgccatcttc gtttgatgga agaagagctg gatgtggtga
    39661 ttcatgctcg tacggagatt gtccaggttt tgggagaaga gactgcctgt gaggaagccc
    39721 gtcaggttat ccaagctttg atggtcttgg tgaaccgtgg gatgaccgtt ggtacgccag
    39781 atgtggtgac tgcaattagc atggtcaaaa acgatgaaat tgataagttt gtcgcccttt
    39841 acgaagaaga aattatcaag gataatactg ggaaaccgat ccgcgttaaa acgttaggtc
    39901 aaaaacttta tgtggacagt gtcaaacagc atgatgtgac ctttggaatt gggcctgcag
    39961 ggacggggaa gacctttctt gcagttactt tggcagtgac tgcccttaaa cgtgggcaag
    40021 tcaagcggat tatcttgaca cgtccagcgg tggaagcagg agagagtcta ggttttcttc
    40081 cgggtgatct taaggagaag gtagatcctt accttagacc tgtttatgat gccttgtatc
    40141 agattctggg gaaagaccaa acaactcgac tcatggagcg tgaaattatc gagattgcgc
    40201 cccttgccta tatgcgtgga cggaccttgg atgatgcctt tgtcattctc gatgaggcgc
    40261 aaaatacgac catcatgcag atgaagatgt tcttgactcg tttaggtttt cattctaaga
    40321 tgattgtcaa tggagatatt agtcagattg acctgccacg taatgtcaag tccggtttga
    40381 ttgatgctca agagaaactc aagaacatcc atcagattga ctttgttcat ttttcagcca
    40441 aggatgtggt tcgccatcca gttgtcgctc agattatccg agcctatgaa tattctactg
    40501 aagttgcaca cgactgattt tgaggaagtt cgcctgcaaa agaatatact tttgagagag
    40561 gaaaatccag ttgtataggc taaaggtttt atccaaaggt ttgagacaac gattaggcac
    40621 gatggaaaga acttttatgt ggctgatgac gatcagtgca tcttcctgtg tcataatcac
    40681 agggcacaag aaagtaggaa tttgaaaaga tgattgacca actatctaag tattacagtt
    40741 gtaggatact aactgaaaag gatattccaa gtattttatc tttatatgaa agtaatcctc
    40801 tgtattttca gcattgtcca ccagagccaa attttgcaac tgtaaaagag gacatgcttt
    40861 gtctacctga aggtaaagct aaggctgata agttttttgt tggattttgg aatggatctg
    40921 accttgtggc tgttatggat tttgtctatg catatcctga tgaggagact gtttttattg
    40981 gtttgtttat ggttgatcaa gcctatcaga ggaaagggat tggtagtcat attgtgacag
    41041 aagcactagc ttattttgct aagaactgtc gaaaggcacg tttggcttat gttaagggaa
    41101 atccgcaatc tcagcatttt tgggaaaagc agggctttaa atcaattgga tgcgaggtta
    41161 agcaagaact ctatacggtt gttatcgctg aacagagcct agaagattag aaatggcatc
    41221 aagtaagaac tatttggaat ttgttttgga acaattatca ggattagatg atgtgactta
    41281 ccgttccatg atgggggagt atattcttta cttccgcggc aagattattg gcggcattta
    41341 tgacgatcgc tttttagtta aacccgtgca agcagtctta gataagattg accaatcttc
    41401 ttttgagttt ccatacaaag gtgccaaaga aatgatttga gtggaagaac ttgataataa
    41461 gatgtttcta taagacctga ttttagctat gtataaccaa ctgccaacgc ccaaacctaa
    41521 aaagaaaaag caagggtgaa cgaagtaaaa aagaagtctg ctaaggccct gtctttgcac
    41581 gggtaaaatt ttatatataa aaagaagctg ggactaaaga gctcagcttc ctttggttta
    41641 tataattgtc attacaagac gaagtggttg ggcgaaactc tgttgatttt attcaattta
    41701 gagtttctta tgcacaattg agtctggaac gaaagtctcc agttgcaaag tatacagtac
    41761 aataaaccaa cgatgtaata gctgatgaca caaagcacag tgggtaggac ttgcgaagtc
    41821 acccttttct tttcaaaatt tatactaaat cattgatatc agtgtagtca cgattaagtc
    41881 cttgagcaac tggtaggcta gttaagtaac cttgataagt ggtcacacct tgacgcaagc
    41941 cttcatcttc agagattgct tgtgcgaatc ctttgccagc caaagcttcg atataaggaa
    42001 gagtgacatt ggttagggcg atggttgaag tgcgagcaac cgcaccaggg atattggcaa
    42061 cggcatagtg gagaacaccg tgtttttcat agacgggttc atcgtgcgtt gtcacacggt
    42121 cagctgtttc gataacgcca ccttggtcaa cagcaacgtc aacgatacag agcctggacg
    42181 catttgtttg accatctcat ctgtcaccaa ttccggtgct tttgcaccag ggatgagaat
    42241 ggctccaatc accacatcag catctctcac acttgcttca atgttgaatg aattagatat
    42301 aagagtttga atttgacttc caaagacttc ttctagaact gagagacgct tggcactaat
    42361 atctaaaata gtcacttgag caccaagacc aagggcgatg cgggcagcat gtgtaccgac
    42421 gacaccatca ccgatgatag ttacttttcc ttttggaaca cctggtacac caccaggtag
    42481 aacaccagat ccaccagctt gcttagtaag gaagtgagct ccgatttaaa cagccatacg
    42541 atctgcaacc tcactcatag gaacgaggag cggtagttgt ccttgattgt cacgaacagt
    42601 ttcataggca attcctgttg tttttgctgc taacatagca tctgctaatt ctggagcagc
    42661 ggccatgtgc aagtaggtga agagaagaag atcgtcgcgc aagtaaccgt attcagaact
    42721 taaaggttct tttactttca caaccaactc tgctgcccaa gcttcaccag cagtagcgac
    42781 aatctcagct ccttgctttt gatagtcagc atcagtaaag ccagaaccga gaccagcatt
    42841 tgtttcgata aggacacgat gaccacgact aactaagcta tgaacacctg caggtgtgag
    42901 ggcgacacgg ttttcgttat ttttaatttc ttttgggatt ccgattaaca ttgagataac
    42961 ctacctttca attgacggtc ttgttttggt tgtcacattc cagttcataa atcaaaaatg
    43021 tgacggtttc attgtatatg aaaccgcttc aaaaatcaag aaaaacttgt catccaaatt
    43081 ttttatgcta gactagtgaa aatcaagctt tgattggttg gaaaagtatg gaatcaattt
    43141 ttgtaaaact tgcccagtat ccgtctatag aaacggagcg tttattgctt agacctgtaa
    43201 ctttggatga tgcggaagca atgtttgact atgcctcgga caagggtaat acacgttaca
    43261 cttttccaac caatcaaagc ttggaagaaa ccaagaataa cattgctcag ttctatttgg
    43321 ctaatccctt gggacgttgg ggaatagaac taaaaagcaa tggtcagttt attggaacca
    43381 ttgacttgca caagattgat tctgttctta agaaggcagc tattggctac attatcaata
    43441 aaaagtattg gaatcaagga ttaacgacag aagccaatcg tgctgtgatt gagctagctt
    43501 ttgagaagat agggatgaat aagttgactg cccttcacga taaggacaat cctgcgtcag
    43561 gaaaggtcat ggagaaatca ggcatgcgtt tttcccatgc agaaccatat gcttgtatgg
    43621 accagcatga aaaaggccga atcgtgacaa gagttcatta tgtcttgacc aaggaagact
    43681 attttgcaaa taaataagca gttgaaaaga aatttttcga ctgttttttc ttcctcttac
    43741 gaataatcta agagaggaga aaatatggaa gcaattatcg agaaaatcaa agagtataaa
    43801 atcatcgtca tctgtactgg tctgggcttg cttgtaggag gatttttcct gctaaaacca
    43861 gctccacaaa cacctgtcaa agagacgaat ttgcaggctg aagtcgcagc tgtttccaag
    43921 gatttggtat ccgaagagga agtgaacaag gaagaaaagg aagaacccct tgaacaagat
    43981 ctaatcacag tagatgtcaa aggtgctgtc aaatcgccag ggatttatga cttgcctgta
    44041 ggtagtcgag tcaatgatgc tgttcagaag gctggtggct tgacagagca agcagacagc
    44101 aagtcgctca atctagctca gaaagttagt gatgaggctc tggtttacgt tcctactaag
    44161 ggagaagaag cagttagcca acagactggt ttggggacag cttcttcaat aagcaaggaa
    44221 aagaaggtca atctcaacaa ggccagtctg gaagaactca agcaggtcaa gggactggga
    44281 ggaaaacgag ctcaggacat tatcgaccat cgtgaggcaa atggcaagtt caagtcagta
    44341 gacgagctca agaaggtctc tggcattggt ggcaaaacaa tagaaaagct taaagactat
    44401 gttacagtgg attaagaatt tctctattcc cctaatttac ctgagttttc tattactttg
    44461 gctttattac gctattttct cagcatctta tcttgctttg ttgggctttg tttttctgct
    44521 agtctgtctc tttatccaat ttccgtggaa atctgctggt aaagttctaa taatttgcgg
    44581 aatctttgga ttttggtttg tttttcaaaa ttggcaacag agtcaagcga gtcaaaatct
    44641 ggcggattct gttgaaaggg tacggatttt acctgatact attaaggtta atggtgatag
    44701 tctatccttt cgtggcaagt ctaacggtcg tgctttccaa gtctattata aactccagtc
    44761 cgaggaggag aaagaagcct ttcaagcttt aaccgacctg catgagatag gactagaagg
    44821 gaagctttcg gagccagaag ggcagagaaa ttttggtggc tttaattacc aagcctatct
    44881 gaagactcag ggaatttacc agactctcaa tatcaaaaaa atccagtcac ttcaaaagat
    44941 tggcagttgg gatataggag aaaacttgtc cagtttacgt cgaaaggctg tggtttggat
    45001 taagacgcac tttccagacc ctatgcgcaa ttacatgaca ggactcttgc tgggatatct
    45061 gaacaccgac tttgaggaga tgaatgagct ttattccagt ctaggaatta tccacctctt
    45121 tgccctatct ggcatgcagg taggtttttt catgaatgga tttaagaaac ttctcttgcg
    45181 attgggcttg acccaagaaa agttgaaatg gctgacttat cccttttccc ttatctatgc
    45241 gggactaatt ggattttcag catcggttat tcgcagtctc ttgcaaaagc tactggctca
    45301 acatggggtt aagggcttgg ataattttgc cttgacggtg cttgtcctct ttattgtcat
    45361 gccaaacttt ttcttgacag caggaggagt cttgtcctgc gcttatgctt ttatcctgac
    45421 catgaccagc aaagaagggg aggggctcaa ggctgttgct agtgaaagtc tagtcatctc
    45481 cttgggcata ttgcccattc tatccttcta ttttgcggaa tttcaacctt ggtctatcct
    45541 tttgaccttt gtcttttcct ttctatttga cttgaccttc ttaccgctct tgtctatttt
    45601 atttgtcctt tcctttctct atccagtcat tcagctgaac tttatctttg aatggttaga
    45661 gggcattatt cgcttggtct cgcaggtggc aaggagaccg cttgtctttg gtcaacccaa
    45721 cgcatggctt ttaatcttat tgttaatttc cttggctttg gtctatgatt tgaggaaaaa
    45781 cattaaagga ttaacagtat tgagtttatt gattacaggt ctctttttcc ttaccaagta
    45841 tccactggaa aatgaaatca ccatgctgga tgtggggcaa ggagaaagta ttttcctacg
    45901 ggatgtaact gggaaaacca ttctcataga tgtaggtggt aaggcagaat cttataagaa
    45961 aatcgaaaaa tggcaagaaa agatgacgac cagcaatgca cagagaagct tgatacccta
    46021 tcttaaaagt cgaggagtag ctaagattga ccagctgatt ttgacaaata cggacaagga
    46081 acatgtcgga gatttgttag aggtgaccaa ggctttccat gtaggggaga ttttagtatc
    46141 aaaaggcagt ttgaagcaga agcaatttgt ggtagaacta caggcgactc aaacaaaggt
    46201 gcgtagtatg acagtagggg agaacttgcc catttttgga agtcagttag aagttctatc
    46261 cccaaggaaa atgggagatg gaggacacga tgatacccta gttctgtatg ggaaattctt
    46321 ggataagcaa tttctcttca cgggaaattt ggaggagaaa ggagagaagg acttgctgaa
    46381 gcactatcca gacttgaaag taaatgtttt gaaagctagc caacatggca ataaaaaatc
    46441 atcaagtcca gcctttctag aaaaactcaa accagagctt actcttatct cagttggaaa
    46501 gagcaatcga atgaaactcc cccatcagga aacattgaca cgactggaag gtatcaatag
    46561 caaagtttac cgaactgacc agcaaggagc tatacggttt aaaggttgga atagttggaa
    46621 aatcgaaagt gttcgatagg aaagataaat gttgtagatt agtgaaataa actaaaaatt
    46681 tgttgcataa taatgataaa aatggtataa tgaaaacgta ttcaatactg aggatataaa
    46741 atcattaaaa attagcaaaa atcgtttaat tagttagttt atgattattg gtctttttca
    46801 gtccagtata tctgctgtga cagccactaa aagttacaag tatgattgga atacggtttt
    46861 ggaatatagt atcaactatc acgaccatca gtatgcttgg attccggaat ggtctcgtta
    46921 ttacagctat tctgagtata aagttggcgg aggctggaac tacgctcgtt atgaggtcat
    46981 aaactattac agcggaggct attaattctt aaagagtgag aaaaaggagg gctagatatg
    47041 ttgcagctta ctcatgtgac cttaaaaacg cgacaagtca tcttgcaaga tgcggatttc
    47101 acctttaaaa agggtaggtt ttatggtctt cttgctatca atggctctgg aaagacgacc
    47161 ctgttccgtg ccattagcaa tttaattccc ataagtagtg gaaatatcgc agttcctcct
    47221 tctttgtttt attatgagag cgttgaatgg ctggatggaa acttaagtgg gatggactac
    47281 cttcgtctca taaaaaacat ctggaagtca gacctaaact tgagagatga aatcgcctac
    47341 tgggaaatgg ctgactatat cagtcttccc atccgcaagt attccttagg catgaagcaa
    47401 cgcttggtga ttgctatgta ttttctcagt caggccaaat gctggctcat ggatgagatt
    47461 acaaatggct tagacgagta ttatcgacag aagttttttg ataggctagc acaaatcgat
    47521 agacaagaac agctggttct tttaagttcc cactataagg aagagttggt tgatatctgc
    47581 gatagagtag taaccattca tcaggggcag atagaagagg tttagtttat gaaagatgtt
    47641 agtctatttt tattgaaaaa agttttcaaa agtcgtttaa actggattat cttactttta
    47701 tttgcatctg tactcggtgt taccttttat ttaaatagtc agactgcaaa ctcacacagc
    47761 ttggagagca ggttggaaag tcgcattgca gccaacgaga gggctatcaa tgaaaatgaa
    47821 gagaaactct cccaaatgtc tgataccagc tcggaggaat accagtttgc taaaaataat
    47881 ttagacgtgc aaaaaaatct tttgacgcga aagacagaaa ttctgacttt attaaaagaa
    47941 gggcgctgga aagaggccta ctatctgcag tggcaagatg aagagaagaa ttatgaattt
    48001 gtatcaaatg acccgactgc tagctctggc ttaaaaatgg gggttgaccg cgaacggaag
    48061 atttaccaag ccctgtatcc cttgaacata aaagcacata ctttggagtt tccgacccac
    48121 gggattgatc agattgtctg gattttagag gttatcatcc caagcttgtt tgtggttgca
    48181 attattttta tgctaacaca actatttgca gaaagatatc aaaatcatct ggacacagct
    48241 cacttatatc ctgtttcaaa agtgacattt gcaatatcct ctcttggagt tggagtggga
    48301 tatgtaactg tgctgtttat cggaatctgt ggcttttctt ttctagtggg aagtctgata
    48361 agtggttttg gacagttaga ttatccctac ccaatttata gcttagtgaa tcaagaagta
    48421 actattggga aaatacaaga tgtattattt cctggcttgc tcttagcttt cttagccttt
    48481 atcgtcattg tggaagttgt gtacttgatt gcttactttt tcaagcaaaa aatgcctgtc
    48541 ctctttcttt cactcattgg gattgttggc ttattgtttg gcatccaaac aattcagcct
    48601 cttcaaagga ttgcacatct gattcccttt acttacttgc gttcagtgga gattttatct
    48661 ggaagattat ctaagcagat tgataatgtc gatctaaatt ggagcatggg gatggtctta
    48721 cttccttgcc tgattatcct tttgttagtg gggattctat ttatcgaaag atggggaagt
    48781 tcacgtaaaa aggaagtttt taaagtttag ttttcctata gggaagctaa agaaaaacta
    48841 acatagggag agaatcaact tggttctctc tttttgattc gaaaaccaaa ccaaaatata
    48901 aacacaaact tttcaaaaaa taacttttta tcttgacaag agctagaaaa cttggtatca
    48961 tataaaagtt gagaaaagca gaagtgagag cttctcgcct tgtgacatta agttgcctgg
    49021 ccctacggat gaaaagtttc gaagaaacgc tatcataacg tgcgggcttg tatatttacg
    49081 agtccgctat tgtttttctc taataaaaca aaagaggtga aaaccatagc aaagcaagac
    49141 ttattcatca atgatgagat tcgtgtacgt gaagttcgct tgattggtct tgagggagaa
    49201 cagctaggca tcaagccact cagtgaagcg caagctttgg ctgataacgc taatgttgac
    49261 ctagtattga ttcaacccca agccaaaccg cctgttgcaa aaattatgga ctacggtaag
    49321 ttcaaatttg agtaccagaa gaagcaaaaa gaacaacgta aaaaacaaag cgttgttact
    49381 gtgaaagaag ttcgtctaag tccaactatt gacaagggtg actttgatac aaaacttcgt
    49441 aatgcacgta agttccttga aaaaggaaat aaagttaagg tatctattcg ctttaagggt
    49501 cgtatgatta cccataaaga gattggtgca aaagttttag ccgagtttgc tgaagcaact
    49561 caagatattg ccatcatcga acaacgtgct aaaatggatg gacgtcaaat gttcatgcaa
    49621 ttggcgccag cgactgacaa aaaataattg tcagaaagtt aaataaagga gaaaaaatca
    49681 tgccaaaaca aaaaacacac cgcgcatcag ctaaacgttt caaacgtaca ggttctggtg
    49741 gacttaaacg tttccgtgct tacacttctc accgtttcca cggaaaaact aagaaacaac
    49801 gtcgtcatct tcgtaaagca tctatggtgc attcaggaga ttacaaacgt atcaaagcaa
    49861 tgcttactcg cttgaaataa tagcttgact gtaagtaaac aattctagaa aatatttgga
    49921 ggaaataaaa catggcacgt gttaaaggtg gcgttgtatc acgcaaacgt cgtaaacgta
    49981 ttcttaaatt agcaaaaggt tactatggag ctaaacacat cttgttccgt actgcaaaag
    50041 aacaagtaat gaactcttac tactatgcat accgtgaccg tcgtcagaaa aaacgtgact
    50101 tccgcaaatt gtggattact cgtatcaatg cggcggctcg tatgaacgga ctttcatact
    50161 cacaattgat gcatggtttg aaattggctg agatcgaagt taaccgtaaa atgcttgctg
    50221 acttggctgt taacgatgca gtagctttca cagctcttgc agatgcagct aaagcaaaac
    50281 ttggtaaata acaactgatg agactggaac aggattgtcc agtcttttta aaaataaagg
    50341 agaaagatat ggcttcaaaa atgctacaca cttgcttacg agtagaaaat cttgaaaaat
    50401 caattgcatt ttatcaagat gcttttggtt ttaaagaatt gcgtcgcaga gattttccag
    50461 accatgcctt cacgattgtc tatctaggtc ttgagggtga tgattatgag ttggagttga
    50521 cttataacta cgatcacggt ccgtatgtgg ttggtgatgg gtttgcccat atcgccctca
    50581 gtacacctga tcttgaggca cttcatcaag aacacagtgc aaaaggctat gaagtgactg
    50641 agccaaatgg tctaccagga actacaccaa actattactt tgttaaagac cctgatggat
    50701 ataaggtcga agtcattcgt gaaaaataat ttcgtgcaag ttaagtagaa tattcgtttt
    50761 ctacttgact ttttttagct gaaagagtat actaataaaa attcaacctt taaggggagt
    50821 ccagagagac tcacaaggtg tcagataaaa gaatagtgca attttctaga ggagaccttt
    50881 tgagtgtgct ctcttgtgtt gtacgatttt aactgaggcc ttgcactagc aaggtctttt
    50941 ctttatctgg tccccttaaa atttaaggag gaaaagttat gaatctcaca tgtaagaagc
    51001 gtttgggtgt cattcggttg gaaaccatga aggtggttgc acaagaggaa atcgcgccag
    51061 caatctttga attagtccta gaaggagaaa tggttgaagc catgcgagca ggccaatttc
    51121 ttcatctgcg tgtaccggac gatgcccatc tcttacgtcg tcctatttca atttcgtcta
    51181 ttgacaaggc aaacaagcag tgtcacctca tttatcggat tgagggagct gggactgcaa
    51241 ttttttcaac cttaagtcag ggagacactc ttgatgtgat ggggcctcag ggaaatggtt
    51301 ttgacttgtc tgaccttgat gagcagaatc aggttctcct tgttggtggt gggattggtg
    51361 ttccaccctt gcttgaggtg gccaaggaat tgcatgaacg tggagtgaaa gtagtgacag
    51421 tcctcggttt tgctaataag gatgctgtta ttttgaaaac ggaattggct cagtatggtc
    51481 aggtctttgt aacgacagat gatggttctt atggcatcaa gggaaatgtt tccgttgtta
    51541 tcaatgattt agatagtcag tttgatgctg tttactcgtg tggggctcca ggaatgatga
    51601 agtatatcaa tcaaaccttt gatgatcacc caagagccta tttatctctg gaatctcgta
    51661 tggcttgtgg gatgggagct tgctatgcct gtgttctaaa agtaccagaa agcgagacgg
    51721 tcagccaacg cgtctgtgaa gatggtcctg ttttccgcac aggaacagtt gtattataag
    51781 gagaaaatta tgactacaaa tcgattacaa gtgtctctac ctggtttgga tttgaaaaat
    51841 ccgattattc cagcatcagg ctgttttggc tttggacaag agtatgccaa gtactatgat
    51901 ttagaccttt taggttctat tatgatcaag gcgacaaccc ttgaaccacg ttttgggaat
    51961 ccaactccaa gagtggcaga gacgcctgct ggtatgctca atgcaattgg cttgcaaaat
    52021 cctggtttag aggttgtttt ggctgaaaag ctaccttggc tggaaagaga atatccaaat
    52081 cttcctatta ttgccaatgt agctggtttt tcaaaacaag agtatgcagc tgtttctcat
    52141 gggatttcca aggcaactaa tgtaaaagct atcgagctca atatttcttg tcccaatgtt
    52201 gaccactgta atcatggact tttgattggt caagatccag atttggctta tgatgtggtg
    52261 aaagcagctg tggaagcctc agaagtgcca gtttatgtca aattaacccc gagtgtgacc
    52321 gatatcgtta ctgtcgcaaa agctgcagaa gatgcgggag caagtggctt gaccatgatc
    52381 aatactctgg ttggaatgcg ctttgacctc aaaaccagaa aaccaatctt ggccaatgga
    52441 acaggtggaa tgtcaggtcc agcagtcttt ccagtagccc tcaaactcat ccgccaagta
    52501 gcccaaacaa cagacctgcc tatcattgga atggggggag tggattcggc tgaagctgcc
    52561 ctagaaatgt atctggctgg ggcatctgct atcggagttg gaacagctaa ctttaccaat
    52621 ccttatgcct gtcctgacat catcgaaaat ttaccaaaag tcatggataa atacggtatt
    52681 agcagtctgg aagaactccg tcaggaagta aaagagtctc tgaggtaaat tgcaatcaat
    52741 ctgttcttga ttttttatta gtttgtaata tgaatttagg agaattttgg tacaataaaa
    52801 taaataagaa cagaggaaga aggttaatga agaaagtaag atttattttt ttagctctgc
    52861 tatttttctt agctagtcca gagggtgcaa tggctagtga tggtacttgg caaggaaaac
    52921 agtatctgaa agaagatggc agtcaagcag cgaatgagtg ggtttttgat actcattatc
    52981 aatcttggtt ctatataaaa gcagatgcta actatgctga aaatgaatgg ctaaagcaag
    53041 gtgacgacta tttttacctc aaatctggtg gctatatggc caaatcagaa tgggtagaag
    53101 acaagggagc cttttattat cttgaccaag atggaaagat gaaacgaaat gcttgggtag
    53161 gaacttccta tgttggtgca acaggtgcca aagtaataga agactgggtc tatgattctc
    53221 aatacgatgc ttggttttat atcaaagcag atggacagca cgcagagaaa gaatggctcc
    53281 aaattaaagg gaaggactat tatttcaaat ccggtggtta tctactgaca agtcagtgga
    53341 ttaatcaagc ttatgtgaat gctagtggtg ccaaagtaca gcaaggttgg ctttttgaca
    53401 aacaatacca atcttggttt tacataaaag aaaatggaaa ctatgctgat aaagaatgga
    53461 ttttcgagaa tggtcactat tattatctaa aatccggtgg ctacatggca gccaatgaat
    53521 ggatttggga taaggaatct tggttttatc tcaaatttga tgggaaaata gctgaaaaag
    53581 aatgggtcta cgattctcat agtcaagctt ggtactactt caaatccggt ggctacatgg
    53641 cagccaatga atggatttgg gataaggaat cttggtttta cctcaagttt gatggcaaaa
    53701 tggctgaaaa agaatgggtt tacgattctc atagtcaagc ctggtactac ttcaaatccg
    53761 gtggttacat gacagccaat gaatggattt gggataagga atcttggttt tacctcaaat
    53821 ctgatgggaa aatagctgaa aaagaatggg tctacaattc tcatagtcaa gcttggtact
    53881 acttcaaatc cggtggttac atgacagcca atgaatggat ttgggataag gaatcttggt
    53941 tttacctcaa gtctgatggc aaaatggctg aaaaagaatg ggtctacgat tctcatagtc
    54001 aagcctggta ctacttcaaa tctggtggct acatggcgaa aaatgagaca gtagatggtt
    54061 atcagcttgg aagcgatggt aaatggcttg gaggaaaagc tacaaatgaa aatgctgctt
    54121 actatcaagt agtgcctgtt acagccaatg tttatgattc agatggtgaa aagctttcct
    54181 atatatcgca aggtagtgtc gtatggctag ataaggatag aaaaagtgat gacaagcgct
    54241 tggctattac tatttctggt ttgtcaggct atatgaaaac agaagattta caagcgctag
    54301 atgctagtaa ggactttatc ccttattatg agagtgatgg ccaccgtttt tatcactatg
    54361 tggctcagaa tgctagtatc ccagtagctt ttcatctttc tgatatggaa gtaggcaaga
    54421 aatattattc ggcagatggc ctgcattttg atggttttaa gcttgagaat cccttccttt
    54481 tcaaagattt aacagaggct acaaactaca gtgctgaaga attggataag gtatttagtt
    54541 tgctaaacat taacaatagc cttttggaga acaagggcgc tacttttaag gaagccgaag
    54601 aacattacca tatcaatgct ctttatctcc ttgcccatag tgccctagaa agtaactggg
    54661 gaagaagtaa aattgccaaa gataagaata atttctttgg cattacagcc tatgatacga
    54721 ccccttacct ttctgctaag acatttgatg atgtggataa gggaatttta ggtgcaacca
    54781 agtggattaa ggaaaattat atcgataggg gaagaacttt tcttggaaac aaggcttctg
    54841 gtatgaatgt ggaatatgct tcagaccctt attggggcga aaaaattgct agtgtgatga
    54901 tgaaaatcaa tgagaagcta ggtggcaagg attagtacta taagtgaata tgatttgagt
    54961 gaatagtaag ttaaaaatcc tgatttcaag taaaatcagg attttttcat ggatgcaatt
    55021 tttttggagt ctggtgtgac gcggagggtc ttttgtcctg tgtaagtgac aaagccgggt
    55081 tttccaccag ttggtttatt gagttttttg acttcaatca tatctacctg caccagattc
    55141 gacaggcgcc cttgagagaa gtaggcagct aactctgctg cgtctgtctt gactgcatca
    55201 gatgggtcaa gatttcctga gatgacaaca tggcttccag gaatgtcctt agcatggaac
    55261 caaagttcct ccttgcgggc cattttaaag gtcaattcct cattttgaag attgtttcgt
    55321 ccgacataga tgatggtttt gccatcgctt gctagatatt gttctagttt tttgcgtttc
    55381 tggattttct cccgttgtct tctgcggata aaacctgttt gaatcaattc ttcacggatt
    55441 tcagcgattt cttccagtcc agcttggttg aggacggttt ctacactttc cagatagaga
    55501 atagtggctt tggtttcttc aatcaaatca gtcaagtatt tgacagcttc tttgagtttc
    55561 tgataccgtt taaaatagcg ttgggcattc tggttgggag tcagagcctt atcaagcgca
    55621 atcatgatag gttggttggt atagtagttg tctaggataa cctggtcttg gtcgttaggc
    55681 acttggtgta ggaaggttgt cagcaattct cctttttgac gaaattcttc agcgttgtct
    55741 gtcgccagta actctttttc ctgttttttg agtttgtgtc ggtttttctg aagttcattt
    55801 tcaacacgac gaatcagttc actggcctgc tgtttgacgc ggtcgcgctc agcctgatcc
    55861 ttatagtagg tgtccaacaa atcagaaaga tttgcaaaag gctctcccac ctgatttgca
    55921 aaaggaactg gactgaagga agtctcagtc aagcatggct tggtttcttg attgaaaaaa
    55981 tttcggaaag cggaaagttt ttcactaacc agtatccttt ccaattcatt tgccgtatcg
    56041 cgtcccagac cttgaaagag gctttgaaga ttttttgctg ttagttcttg ggtttgcagg
    56101 atttcaaaga gcttttcatc cttgatagta aaaggattga gagattctgt acttggcgga
    56161 gcgatatagg tcgatcctgg aagtaaggtg cggtagctat tttgtgaaaa accgacgtgt
    56221 ttgataactt cgaggatttt atgactgctt ttatcgacca gtagaatatt actgtgtttc
    56281 cccataattt caataatcaa ggtagcctgg atatggtctc caatctcgtt tttattggaa
    56341 actgtcattt ccacaatacg gtcattttcc acttgctcaa tcgactcaat cagggccccc
    56401 tgcaaatact ttctcaaaac catgataaag gtagaaggtt gagctggatt ttcaaaagtc
    56461 gtttgggtca gctgaatgcg tccaaaaact ggatgggcag aaaggagcag gcgatggctt
    56521 tggcgattgc tgcggatttg caagaccaac tcttgttcaa aaggctgatt gattttctgg
    56581 atgcgaccat tcactaattc gtttcgcaat tcctcaacta tgtggtgtaa aaaaaatcca
    56641 tcaaatgaca tcgttctctc cttgtgattg tattccatag tattatatca aaaaggtaga
    56701 ataaaatcat ggaaatgtgg tataataaag ccaagtaaag agaaatgaga agcacatgta
    56761 tattgaaatg gtagatgaaa ctggtcaagt ttcaaaagaa atgttgcaac aaacccaaga
    56821 aattttggaa tttgcagccc aaaaattagg aaaagaagac aaggagatgg cagtcacttt
    56881 tgtgaccaat gagcgtagtc atgaacttaa tctggagtac cgtgacaccg accgtccgac
    56941 agatgtcatc agccttgagt ataaaccaga attggaaatt gcctttgacg aagaggattt
    57001 gcttgaaaat ccagaattgg cagagatgat gtctgagttt gatgcctata ttggggaatt
    57061 gttcatctct atcgataagg ctcatgagca ggccgaagaa tatggtcaca gctttgagcg
    57121 tgagatgggc ttcttggcag tacacggctt tttacatatt aacggctatg atcactacac
    57181 tccggaagaa gaagcggaga tgttcggttt acaagaagaa attttgacag cctatggact
    57241 cacaagacaa taaacgaaaa tggaaaaatc gtgacctgat atccagttta gaatttgcca
    57301 tcacagggat ttttactgct atcaaggaag aacgaaatat gcgaaaacat gcagtgacgg
    57361 ctctagtggt catccttgca ggttttgttt ttcaggtgtc acgaatcgaa tggctctttc
    57421 tcctattgag cattttcttg gtagtagcct ttgagattat caactctgct attgaaaata
    57481 tggtggattt ggccagtcac tatcactttt ccatgctggc taaaaatgcc aaggatatgg
    57541 cggctggcgc ggtattagtg gtttctcttt tcgcagcctt aacaggtgca ttgatttttc
    57601 tcccacgaat ctgggattta ttattttaaa cagtaagagg aaattatgac ttttaaatca
    57661 ggctttgtag ccattttagg acgtcccaat gttgggaagt caaccttttt aaatcacgtt
    57721 atggggcaaa agattgccat catgagtgac aaggcgcaga caacgcgcaa taaaatcatg
    57781 ggaatttaca cgactgataa ggagcaaatt gtctttatcg acacaccagg gattcacaaa
    57841 cctaaaacag ctctcggaga tttcatggtt gagtctgcct acagtaccct tcgcgaagtg
    57901 gacactgttc ttttcatggt gcctgctgat gaagcgcgtg gtaaggggga cgatatgatt
    57961 attgagcgtc tcaaggctgc caaggttcct gtgattttgg tggtgaataa aatcgataag
    58021 gttcatccag accagctctt gtctcagatt gatgacttcc gtaatcaaat ggactttaag
    58081 gaaattgttc caatctcagc ccttcaggga aataacgtgt ctcgtctagt ggatattttg
    58141 agtgaaaatc tggatgaagg tttccaatat ttcccgtctg atcaaatcac agaccatcca
    58201 gaacgtttct tggtttcaga aatggttcgc gagaaagtct tgcatctaac tcgtgaagag
    58261 attccgcatt ctgtagcagt agttgttgac tctatgaaac gagacgaaga gacagacaag
    58321 gttcacatcc gtgcaaccat catggtcgag cgcgatagcc aaaaagggat tatcatcggt
    58381 aaaggtggcg ctatgcttaa gaaaatcggt agcatggccc gtcgtgatat cgaactcatg
    58441 ctaggagaca aggtcttcct agaaacctgg gtcaaggtca agaaaaactg gcgcgataaa
    58501 aagctagatt tggctgactt tggctataat gaaagagaat actaagtaga ggtaggctca
    58561 tgcctgcttc ttgtttttac agaaggagga cttatgcctg aattacctga ggttgaaacc
    58621 gtttgtcgtg gcttagaaaa attgattata ggaaagaaga tttcgagtat agaaattcgc
    58681 taccccaaga tgattaagac ggatttggaa gagtttcaaa gggaattgcc tagtcagatt
    58741 atcgagtcaa tgggacgtcg tggaaaatat ttgctttttt atctgacaga caaggtcttg
    58801 atttcccatt tgcggatgga gggcaagtat ttttactatc cagaccaagg acctgaacgc
    58861 aagcatgccc atgttttctt tcattttgaa gatggtggca cgcttgttta tgaggatgtt
    58921 cgcaagtttg gaaccatgga actcttggtg cctgaccttt tagacgccta ctttatttct
    58981 aaaaaattag gtcctgaacc aagcgaacaa gactttgatt tacaggtctt tcaatctgcc
    59041 cttgccaagt ccaaaaagcc tatcaaatcc catctcctag accagacctt ggtagctgga
    59101 cttggcaata tctatgtgga tgaggttctc tggcgagctc aggttcatcc agctagacct
    59161 tcccagactt tgacagcaga agaagcgact gccattcatg accagaccat tgctgttttg
    59221 ggccaggctg ttgaaaaagg tggctccacc attcggactt ataccaatgc ctttggggaa
    59281 gatggaagca tgcaggactt tcatcaggtc tatgataaga ctggtcaaga atgtgtacgc
    59341 tgtggtacca tcattgagaa aattcaacta ggcggacgag gcacccactt ttgtccaaac
    59401 tgtcaaagga gggactgatg agaaaaatca tcggaatcac tgggggaatt gcctctggta
    59461 agtcaactgt gacaaatttt ctaagacagc aaggctttca agtagtggat gccgacgcag
    59521 tcgtccacca actacagaaa tctggtggtc gtctgtttga ggctctagta cagcactttg
    59581 ggcaagaaat cattcttgaa aacggagaac tcaatcgccc tctcctagct agtctcatct
    59641 tttcaaatcc tgaagagcaa aaatggtcta agcaaattca aggggagatt atccgtgagg
    59701 aactggctac tttgagagaa cagttggctc agacagaaga gattttcttc atggatattc
    59761 ccctactttt tgagcaggac tacagcgatt ggtttgctga gacttggttg gtctatgtgg
    59821 accgagatac ccaagtagaa cgcttaatga aaagggacca gttgtccaaa gatgaagctg
    59881 agtctcgtct ggcagcccag tggcctttag aaaaaaagaa agatttggcc agccaggttc
    59941 ttgataataa tggcaatcag aaccagcttc ttaatcaagt gcatatcctt cttgagggag
    60001 gtaggcaaga tgacagagat taactggaag gataatctgc gcattgcctg gtttggtaat
    60061 tttctgacag gagccagtat ttctttggtt gtacctttta tgcccatctt cgtggaaaat
    60121 ctaggtgtag ggagtgagca agtcgctttt tatgcaggct tagcaatttc tgtctctgct
    60181 atttccgcgg cgctcttttc tcctatttgg ggtattcttg ctgacaaata cggccgaaaa
    60241 cccatgatga ttcgggcagg tcttgctatg actatcacta tgggaggctt ggcctttgtc
    60301 ccaaatatct attggttaat ctttcttcgt ttactaaacg gtgtatttgc aggttttgtt
    60361 cctaatgcaa cggcactgat agccagtcag gttccaaagg agaaatcagg ctctgcctta
    60421 ggtactttgt ctacaggcgt agttgcaggt actctaactg gtccctttat tggtggcttt
    60481 attgcagaat tatttggcat tcgtacagtt ttcttactgg ttggtagttt tctattttta
    60541 gctgctattt tgactatttg ctttatcaag gaagtttttc aaccagtagc caaggaaaag
    60601 gccattccaa caaaggaatt atttacctcg gttaaatatc cctatctttt gctcaatctc
    60661 tttttaacca gttttgtcat ccaattttca gctcaatcga tcggccctat tttggctctt
    60721 tatgtacgcg acttagggca gacagagaat cttctttttg tctctggttt gattgtgtcc
    60781 agtatgggct tttccagtat gatgagtgca ggagttatgg gaaagctagg tgacaaggtg
    60841 ggcaatcatc gtctcttggt tgtcgcccaa ttttattcag tcatcatcta tctcctctgt
    60901 gccaatgcct ctagccccct tcaactagga ctctatcgat tcctctttgg cttgggaacc
    60961 ggtgccttga ttcccggggt taatgcccta ctcagcaaaa tgactcccaa agccggcatt
    61021 tcgagggtct ttgccttcaa tcaggtattc ttttatctgg gaggtgttgt tggtcccatg
    61081 gcaggttctg cagtagcagg tcaatttggc taccatgctg tcttttatgc gacaagcctt
    61141 tgtgttgcct ttagttgtct ctttaacctg attcaatttc gaacattatt aaaagtaaag
    61201 gaaatctagt gcgagtaaaa attaatctca aatgctcctc ttgtgacagt atcaattacc
    61261 taaccagtaa aaattcaaaa acccatccag acaagattga ggttttaaag tattgtccca
    61321 aggaaagaaa agtaacccta catcttgaat ctaagtagat tttatggtaa aataataggg
    61381 attttaagga gtttgatatg tataacctat tattaaccat tttattagta ttatctgttg
    61441 tgattgtgat tgcaattttc atgcaaccaa ccaaaaacca atccagcaat gtatttgatg
    61501 ccagttcagg tgatttgttt gaacgcagta aagctcgcgg ttttgaagct gtaatgcagc
    61561 gtttgacagg gattttagtc tttttctggc tagccattgc cttagcattg acggtattat
    61621 caagtagata agaaaataat gggcaggact aggtctttgc ctctttttat ttttaaagga
    61681 tgtttgagaa ggttttacag taaaagaaaa ttaaaaaatc tagaaagaaa atatgaaaga
    61741 tagaataaaa gaatatttac aagacaaggg aaaggtgact gttaatgatt tggctcaggc
    61801 tttgggaaaa gacagttcca aggattttcg tgagttgatt aaaaccttgt ccttaatgga
    61861 aagaaagcac caaattcgtt ttgaagaaga tggcagtctg accttggaag ccaagaaaaa
    61921 acatgagatt accctcaagg ggatttttca tgcccataaa aatggttttg gttttgtcag
    61981 cctagaaggg gaagaggacg acctttttgt agggaaaaat gatgtcaact atgctattga
    62041 tggtgatacc gtcgaggtag tgattaagaa agtcgctgac cgcaataagg gaacagcagc
    62101 agaagccaaa attattgata tcctagaaca cagtttgaca acagttgtcg ggcaaatcgt
    62161 tctggatcag gaaaagccta agtatgctgg ctatattcgt tcaaaaaatc agaaaatcag
    62221 tcaaccgatt tatgttaaga aaccagccct aaagttagaa ggaacagaag ttctcaaggt
    62281 ctttatcgat aaatacccaa gcaagaaaca tgatttcttt gtcgcgagtg ttctcgatgt
    62341 ggtgggacac tcaacggatg tcggaattga tgttcttgag gtcttggaat caatggacat
    62401 tgtatccgag tttccagaag ctgttgtcaa ggaagcagaa agtgtgcctg atgctccgtc
    62461 tcaaaaggat atggaaggtc gtctggatct aagagatgaa attaccttta ccattgacgg
    62521 tgcggatgcc aaggacttgg acgatgcagt gcatatcaag gctctgaaaa atggcaatct
    62581 ggagcttggg gttcacatcg cagatgtttc ctattatgtg accgagggtt ctgcccttga
    62641 caaggaagcc cttaaccgtg cgacttctgt ttacgtgaca gaccgagtgg tgccaatgct
    62701 tccagaacga ctatcaaatg gcatctgctc tctcaatccc caagttgacc gcctgaccca
    62761 gtctgctatt atggagattg ataaacatgg tcgtgtggtc aactatacca ttacacaaac
    62821 agttatcaag accagttttc gtatgaccta tagcgatgtc aatgatatcc tagctggcga
    62881 tgaagaaaag agaaaagaat accataaaat tgtaccaagt atcgaactca tggccaagct
    62941 tcatgaaact ttagaaaaca tgcgtgtgaa acgtggagct ctcaattttg ataccaatga
    63001 agcgaagatt ttagtggata aacaaggtaa gcctgttgat atcgttcttc ggcagcgtgg
    63061 cattgccgag cggatgattg agtcttttat gttgatggct aatgaaacag ttgccgaaca
    63121 tttcagcaag ttggatttgc cttttatcta ccgaattcac gaggagccta aggctgaaaa
    63181 ggttcagaag tttattgatt atgcttcgag ttttggcttg cgcatttatg ggactgccag
    63241 tgagattagc caggaggcac ttcaagacat catgcgtgct gttgagggag aaccttatgc
    63301 agatgtattg tccatgatgc ttcttcgctc tatgcagcag gctcgttatt cggagcacaa
    63361 tcacggccac tatggactag ctgctgacta ttatactcac tttaccagtc caattcgtcg
    63421 ttatccagac cttcttgttc accgtatgat tcgggattac ggccgttcta aggaaatagc
    63481 agagcatttt gaacaagtga ttccagagat tgcgacccag tcttccaacc gtgaacgtcg
    63541 tgccatagaa gctgagcgtg aagtcgaagc catgaaaaag gctgagtata tggaagaata
    63601 cgtgggtgaa gagtatgatg cagttgtatc aagtattgtc aaattcggtc tctttgtcga
    63661 attgccaaac acagttgaag gcttgattca catcactaat ctacctgaat tttatcattt
    63721 caatgagcgt gatttgactc ttcgtggaga aaaatcaggt atcactttcc gagtgggtca
    63781 gcagatccgt atccgtgttg aaagagcgga taaaatgact ggagagattg atttttcatt
    63841 cgtacctagt gagtttgatg tgattgaaaa aggcttgaaa cagtctagtc gtagtggcag
    63901 agggcgtggt tcaaatcgtc gttcggataa gaaggaagac aagagaaaat caggacgctc
    63961 aaatgataag cgtaaacatt cacaaaaaga caagaagaaa aaaggaaaga aaccttttta
    64021 caaggaagta gctaagaaag gagccaagca tggcaaaggg cgagggaaag gtcgtcgcac
    64081 aaaataaaaa ggcacgccac gactatacaa tcgtagatac gctagaggca gggatggtcc
    64141 tgactggaac tgaaatcaag agtgtacgag ctgctcgaat taatctcaag gatggctttg
    64201 ctcaagtgaa aaatggagaa gtttggctga gcaatgttca tatcgcacct tacgaagagg
    64261 gcaatatctg gaaccaggaa ccagaacgtc gtcgtaaact cctgctccat aaaaagcaaa
    64321 ttcaaaaatt ggaacaagag accaaaggga caggaatgac cttagttccc cttaaggtct
    64381 atataaaaga tggctacgct aagcttcttt taggacttgc caaagggaag catgactatg
    64441 acaaacggga gtctatcaaa cgtcgtgagc aaaatcgaga tatcgcgcgt gtgatgaaag
    64501 ctgttaatca gcgataaaaa gaggaattga aaatggaaaa attagttgcc tataaacgca
    64561 tgcctttgtg gaataaacaa acaatgcctg aagctgttca gcaaaagcac aatacaaaag
    64621 ttgggacttg ggggaaaatt actgtcttga agggagctct caagtttatt gaattgacag
    64681 aagaagggga agttctagct gaacacctct ttgaagcagg ggcagacaat ccaatggccc
    64741 agcctcaagc ctggcaccga gtggaagctg ccacagatga tgtggaatgg tacttggaat
    64801 tttattgtaa acctgaggat tattttgcta aaaaatacaa taccaaacct gttcattcag
    64861 aggtcctaga ggccatgcag acagtgaaac aagggaaagc tttggatttg ggttgtggtc
    64921 aggggcgtaa ttctcttttt ctagcccagc aagattttga tgtgacggct gtagatcaaa
    64981 atggactggc tcttgaaatc ttgcaaagca ttgtggagca ggaagatttg gacatacctg
    65041 ttgaccttta cgatatcaat tcagctagca ttggacaaga atatgatttt atcgtttcaa
    65101 cagttgttct catgtttcta caagcggacc gcattccagc tattattcaa aatatgcagg
    65161 agaaaaccag tgttggtggt tacaacctta tcgtttgtgc catggacacg gaggactatc
    65221 cttgctcggt taacttccca ttcaccttta aagaaggaga actggcagac tattacaagg
    65281 attgggaatt ggttaagtac aatgaaaatc caggccattt gcatcgtcgc gatgagaatg
    65341 gcaatcgtat tcaactacgc tttgcgacct tactagctaa gaaaatcaag taaacacaca
    65401 tgaagattag gaattttcct gatctttttt cttttttacg aatgatatag aaaaggaggg
    65461 aattcatgtt tgttgcgaga gatgctaggg gagaattggt aaatgtgtta gaggataaac
    65521 ttgagaagca agcatacacc tgcccagctt gtggaggcca gctccatttg cgtcaaggac
    65581 caagtgtacg gacgcatttt gcccataaat ccttaaaaga ctgtgatttt ttctttgaaa
    65641 atgaaagtcc agaacacctg gccaataagg aatccctcta tcactggtta aaaaaagaga
    65701 caaaggttca attagagtac ccgctttcag aacttaaaca gattgcggat gtatttgtaa
    65761 atggcaatct agctctagaa gttcagtgta gtcccttgcc tcagaaagtc cttaaagagc
    65821 gaagtgaggg atatcgtagt cagggttacc aagtactgtg gttgctgggt caaaaactgt
    65881 ggctcaagga gcgtttgact cgtctacagc aaggttttct ttatttcagt caaaacatgg
    65941 gcttttatgt ttgggaatta gacaaggaaa aacaagtttt aagactcaaa tacctgattt
    66001 accaggatct ccgcggtaaa ctccattatc aaatcaagga attttcctat ggtcaaggta
    66061 gtttattgga aatattgcgt cttccctata agagacaaaa aatatctcat tttacagttt
    66121 ctgaggacaa ggacatctgt cgctatatcc ggcaacaact ttattatcaa aatctctttt
    66181 ggatgaaaga acaagcagaa gcctatcaaa agggagaaaa tatcctgact tatggactga
    66241 aagaatggta tccacaaatt cgaccaatag tgggcaaatt tttccagatt gaacaagact
    66301 tgactagcta ttatcagcac ttttatacct attaccaaaa aaatcctcaa aatgattggc
    66361 aaaagcttta tccaccagcc ttttatcagc aatatttctt gaaaaatatg gtagaataga
    66421 aaggatggag gaatctaatg gtattacaaa gaaatgaaag aaatgaaata aatgaaaaag
    66481 atacatggga tctatcaacg atctacccaa ctgaccaggc ttgggaagaa gccttaaaag
    66541 atttaacaga acaattggag acagtagccc agtatgaagg ccatctcttg gatagtgcgg
    66601 ataacctact agaaatcact gaattttctc ttgaaatgga acgccagatg gagaagcttt
    66661 acgtttatgc tcatatgaag aatgaccagg atacacgtga agctaagtat caagagtact
    66721 atgccaaggc catgacactc tacagccagt tagaccaagc cttttcattc tatgatcctg
    66781 aatttatgga gattagcgaa aagcagtatg ctgacttttt agaagctcaa ccaaagctgc
    66841 aggtttatca acactatttt gacaagctct tgcaaggcaa ggatcacgtt ctttcacaac
    66901 gtgaagaaga attattggct ggagctggag aaatctttgg ttcagcaagt gaaaccttcg
    66961 ctatcttgga caatgcggat attgtgttcc cttatgtcct agacgatgat ggtaaagaag
    67021 ttcagctatc tcatgggact tacacacgtt tgatggagtc taaaaaacgt gaggttcgcc
    67081 gtggtgccta tcaagctctt tatgcgactt acgaacaatt ccaacacacc tatgccaaaa
    67141 ccttgcaaac caatgttaag gtgcaaaatt accgtgctaa agttcgtaac tacaagagtg
    67201 ctcgtcatgc agccctcgca gcgaattttg ttccagaaag tgtttatgac aatttggtag
    67261 cagcagttcg caagcatttg ccactcttac atcgctatct tgagcttcgt tcaaaaatct
    67321 tggggatttc agatctcaag atgtacgatg tctacacacc gctttcatct gttgaataca
    67381 attttaccta ccaagaagcc ttgaaaaaag cagaagatgc tttggcagtc ttgggtgagg
    67441 attacttgag ccgtgtcaaa cgtgccttca gcgagcgttg gattgatgtt tacgaaaatc
    67501 aaggcaagcg ttcaggtgcc tactctggtg gttcttacga taccaatgcc tttatgcttc
    67561 tcaactggca ggacaatctg gacaatctct ttactcttgt tcatgaaaca ggtcacagta
    67621 tgcattcaag ctatactcgt gaaactcagc cttatgttta cggagattac tctatctttt
    67681 tggctgagat tgcctcaact accaatgaaa atatcttgac ggagaaatta ttggaagaag
    67741 tggaagacga cgcaacacgc tttgctattc tcaataactt cctagatggt ttccgtggaa
    67801 cagttttccg ccaaactcaa tttgctgagt ttgaacacgc cattcaccaa gcagatcaaa
    67861 atggggaggt cttgacaagc gatttcctaa ataaactcta cgcagacttg aaccaagagt
    67921 attatggttt gagtaaggaa gacaatcctg aaatccaata cgagtgggct cgcattccac
    67981 acttctacta taactactat gtatatcaat attcaactgg ctttgcggcc gcctcagcct
    68041 tggctgaaaa aattgtccat ggtagtcaag aagaccgtga ccgctatatc gactacctca
    68101 aggcaggtaa gtcggactat ccacttaatg tcatgagaaa agctggtgtt gatatggaga
    68161 aggaagacta cctcaacgat gcctttgcag tctttgaacg ccgtttaaat gagtttgaag
    68221 cccttgttga aaaattagga ttggcataaa atggttgaat cgtatagtaa gaatgctaac
    68281 cataacatgc gtcgtcctgt cgtcaaagaa gaaattgtag acttgatgcg tcagcgtcaa
    68341 aagcaggtca caggtttctt gaaagaattg gaagactttg cccgcaagga aaatattcct
    68401 attattcccc atgaaacggt tgcttatttc cgttttctta tggaaaccat gcagcctaaa
    68461 aatattctgg aaattgggac ggctatcggt ttttcagctc tcttgatggc tgaacatgcg
    68521 ccaaatgcta agattacaac tattgatcgt aatccagaaa tgattggttt tgccaaggaa
    68581 aattttgccc agtttgacag tcgcaagcaa atcactctcc tagagggaga tgcggtggat
    68641 gtcttatcta cactgacaga gtcttatgat ttcgtcttta tggattctgc caagtctaaa
    68701 tacatcgtct ttctgccaga aatcctcaaa catttggaag ttggtggtgt ggttgtcttg
    68761 gatgatattt ttcaaggtgg tgatgttgcc aaggatatta tggaagtccg tcgtggtcag
    68821 cgaaccattt atcgaggcct tcaaaaatta ttttatgcaa ccttagacaa tccagaactc
    68881 accgcaacat tagtgccttt aggagatggt attctcatgc ttcgtaaaaa tgtagcagat
    68941 gttcaactgt ctgaaagcga atgattttca gaaaaattta agaaaaaata gtaaaataga
    69001 tagagtaaca cttatctcaa aggagtagac atgaagaaaa aattattggc aggtgccatc
    69061 acactattat cagtagcaac tttagcagct tgttcgaaag ggtcagaagg ggcagacctt
    69121 atcagcatga aaggggatgt catcacagaa catcaatttt atgagcaagt gaaaaacaac
    69181 ccttcagccc aacaagtctt gttaaatatg accatccaaa aagtttttga aaaacaatat
    69241 ggctcagagc ttgatgataa agaggttgat gatactattg ccgaagaaaa aaaacaatat
    69301 ggcgaaaact accaacgtgt cttgtcacaa gcaggtatga ctcttgaaac acgtaaagct
    69361 caaattcgta caagtaaatt agttgagttg gcagttaaga aggtagcaga agctgaattg
    69421 acagatgaag cctataagaa agcctttgat gagtacactc cagatgtaac ggctcaaatc
    69481 atccgtctta ataatgaaga taaggccaaa gaagttctcg aaaaagccaa ggcagaaggt
    69541 gctgattttg ctcaattagc caaagataat tcaactgatg aaaaaacaaa agaaaatggt
    69601 ggagaaatta cctttgattc tgcttcaaca gaagtacctg agcaagtcaa aaaagccgct
    69661 ttcgctttag atgtggatgg tgtttctgat gtgattacag caactggtac acaagcttac
    69721 agtagccaat attacattgt aaaactcact aagaaaacag aaaaatcatc taatattgat
    69781 gactacaaag aaaaattaaa aactgttatc ttgactcaaa aacaaaatga ttcaacattt
    69841 gttcaaagca ttatcggaaa agaattgcaa gcagccaata tcaaggttaa ggaccaagcc
    69901 ttccaaaata tctttaccca atatatcggt ggtggagatt caagctcaag cagtagtaca
    69961 tcaaacgaat agtccaaatc aatgagtcag ggaaaaaaac tcgacttcag gaaaaaatga
    70021 agcaaacatt cccacaataa aacgcatagt acaaggtttg tactgccccc aaaagttaga
    70081 caattaattt atctgaagga tttagttctg tattgcacag ggctaagtcc ttttagtttt
    70141 accttaattc tcttattgtt ctaataatca atatagtcta taatggcttg ttccaattga
    70201 ttaagtgatt taaatgtttt ctcatagcca taaaacattt cggattttaa aatgccaaag
    70261 aaagattcca tcctaccgtt gtcttggctg tttcctttgc gtgacataga tgcttgaatt
    70321 cccttactct ctaggaagcg atgataagaa tcgtgttggt attgccagcc ttggtcacta
    70381 tggagaatcg tattctcgta gtgcttctct ttgaatgcct gttccaacat taacgatcaa
    70441 tcaatttaat catgtaccta a
//
LOCUS       DAVHSY010000007        69050 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.007, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000007 DAVHSY010000000
VERSION     DAVHSY010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 69050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69050
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.007"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(34..231)
                     /locus_tag="VVR43_000582"
     CDS             complement(34..231)
                     /locus_tag="VVR43_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU6148982.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(306..1082)
                     /locus_tag="VVR43_000583"
     CDS             complement(306..1082)
                     /locus_tag="VVR43_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU6148983.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            1204..1950
                     /locus_tag="VVR43_000584"
     CDS             1204..1950
                     /locus_tag="VVR43_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6148984.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            1963..2943
                     /locus_tag="VVR43_000585"
     CDS             1963..2943
                     /locus_tag="VVR43_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU6148985.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            3138..3458
                     /locus_tag="VVR43_000586"
     CDS             3138..3458
                     /locus_tag="VVR43_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6148986.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            3504..3812
                     /locus_tag="VVR43_000587"
     CDS             3504..3812
                     /locus_tag="VVR43_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6148987.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            3829..5127
                     /locus_tag="VVR43_000588"
     CDS             3829..5127
                     /locus_tag="VVR43_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6148988.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLAMSTMVYFPFFKIQDRLACQNEIKQS"
     gene            5278..7716
                     /locus_tag="VVR43_000589"
     CDS             5278..7716
                     /locus_tag="VVR43_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU6148989.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            7735..8403
                     /locus_tag="VVR43_000590"
     CDS             7735..8403
                     /locus_tag="VVR43_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU6148990.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            8421..9509
                     /locus_tag="VVR43_000591"
     CDS             8421..9509
                     /locus_tag="VVR43_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU6148991.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            9964..12465
                     /locus_tag="VVR43_000592"
     CDS             9964..12465
                     /locus_tag="VVR43_000592"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU6148992.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAYLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVTTDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYIDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            12604..13446
                     /locus_tag="VVR43_000593"
     CDS             12604..13446
                     /locus_tag="VVR43_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6148993.1"
                     /translation="MNRLVNDSRKCEILLFKISIIVVSVIVLVMSIVGAYYFKNCLWD
                     KESLNLTLTLDTLFAVFITFFSFSNDKSSNIFGISPNEIIRTQSEVYQFLFTKSFATL
                     LIVTNLLSIIHYFGAKNLIVSFNETYPRIQSSVGIMWLPLFGILIIYFIWLLIEGLKY
                     IRKINYIIQNREIIYFYSQVKVVDKLTDSESKKYGEYIDLYESCRQNNLSVLLNFLQN
                     SDDKRGVIASNSVRIMFESLDKADQIAALNICRNYVARENVLNKEDAEKLLNEIDKKL
                     EISR"
     gene            13502..14197
                     /locus_tag="VVR43_000594"
     CDS             13502..14197
                     /locus_tag="VVR43_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6148994.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDAL
                     NLPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            14209..14625
                     /locus_tag="VVR43_000595"
     CDS             14209..14625
                     /locus_tag="VVR43_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6148995.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEHALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPIYQRQGIGSALMKEALKDYKDAYQVQ
                     LVTEETEKNVGFYRSMGFEILSTYNCIGMTWANREK"
     gene            complement(15440..15532)
                     /locus_tag="VVR43_000596"
     CDS             complement(15440..15532)
                     /locus_tag="VVR43_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU6148996.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            15693..16664
                     /gene="ruvB"
                     /locus_tag="VVR43_000597"
     CDS             15693..16664
                     /gene="ruvB"
                     /locus_tag="VVR43_000597"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU6148997.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            16753..17217
                     /locus_tag="VVR43_000598"
     CDS             16753..17217
                     /locus_tag="VVR43_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEU6148998.1"
                     /translation="MAAGSVRNFIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLE
                     KKLREDFPQYQWELKNQVYMHQHSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFE
                     LYAPYGLEDILNFQVRPTPHFLENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            17448..18206
                     /locus_tag="VVR43_000599"
     CDS             17448..18206
                     /locus_tag="VVR43_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU6148999.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            18215..19018
                     /locus_tag="VVR43_000600"
     CDS             18215..19018
                     /locus_tag="VVR43_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU6149000.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            19040..20299
                     /gene="rseP"
                     /locus_tag="VVR43_000601"
     CDS             19040..20299
                     /gene="rseP"
                     /locus_tag="VVR43_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU6149001.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLGQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            20312..22165
                     /locus_tag="VVR43_000602"
     CDS             20312..22165
                     /locus_tag="VVR43_000602"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU6149002.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            22265..23644
                     /gene="bglA"
                     /locus_tag="VVR43_000603"
     CDS             22265..23644
                     /gene="bglA"
                     /locus_tag="VVR43_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU6149003.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            23836..25644
                     /gene="glmS"
                     /locus_tag="VVR43_000604"
     CDS             23836..25644
                     /gene="glmS"
                     /locus_tag="VVR43_000604"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU6149004.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLSLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(25782..25859)
                     /locus_tag="VVR43_000605"
                     /pseudo
     CDS             complement(25782..25859)
                     /locus_tag="VVR43_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            25916..26965
                     /locus_tag="VVR43_000606"
     CDS             25916..26965
                     /locus_tag="VVR43_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU6149005.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(27065..30871)
                     /gene="spuA"
                     /locus_tag="VVR43_000607"
     CDS             complement(27065..30871)
                     /gene="spuA"
                     /locus_tag="VVR43_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU6149006.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGVDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDVHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQEAQA
                     SSVKEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLL
                     KNKKEN"
     gene            31288..31701
                     /gene="rpsL"
                     /locus_tag="VVR43_000608"
     CDS             31288..31701
                     /gene="rpsL"
                     /locus_tag="VVR43_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU6149007.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            31721..32191
                     /gene="rpsG"
                     /locus_tag="VVR43_000609"
     CDS             31721..32191
                     /gene="rpsG"
                     /locus_tag="VVR43_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU6149008.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            32616..34697
                     /gene="fusA"
                     /locus_tag="VVR43_000610"
     CDS             32616..34697
                     /gene="fusA"
                     /locus_tag="VVR43_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU6149009.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            34801..39192
                     /locus_tag="VVR43_000611"
     CDS             34801..39192
                     /locus_tag="VVR43_000611"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU6149010.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQTANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            39294..39557
                     /locus_tag="VVR43_000612"
     CDS             39294..39557
                     /locus_tag="VVR43_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU6149011.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            39550..39828
                     /locus_tag="VVR43_000613"
     CDS             39550..39828
                     /locus_tag="VVR43_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEU6149012.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            39849..40001
                     /locus_tag="VVR43_000614"
     CDS             39849..40001
                     /locus_tag="VVR43_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149013.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            40023..41264
                     /locus_tag="VVR43_000615"
     CDS             40023..41264
                     /locus_tag="VVR43_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU6149014.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            41274..41504
                     /locus_tag="VVR43_000616"
     CDS             41274..41504
                     /locus_tag="VVR43_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU6149015.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            41772..42494
                     /locus_tag="VVR43_000617"
     CDS             41772..42494
                     /locus_tag="VVR43_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU6149016.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            42712..44046
                     /gene="pepC"
                     /locus_tag="VVR43_000618"
     CDS             42712..44046
                     /gene="pepC"
                     /locus_tag="VVR43_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU6149017.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAK"
     gene            complement(44102..45013)
                     /locus_tag="VVR43_000619"
     CDS             complement(44102..45013)
                     /locus_tag="VVR43_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6149018.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(45037..45840)
                     /locus_tag="VVR43_000620"
     CDS             complement(45037..45840)
                     /locus_tag="VVR43_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU6149019.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(45868..46857)
                     /gene="manX"
                     /locus_tag="VVR43_000621"
     CDS             complement(45868..46857)
                     /gene="manX"
                     /locus_tag="VVR43_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU6149020.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(47090..48109)
                     /gene="adhP"
                     /locus_tag="VVR43_000622"
     CDS             complement(47090..48109)
                     /gene="adhP"
                     /locus_tag="VVR43_000622"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU6149021.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(48448..49260)
                     /locus_tag="VVR43_000623"
     CDS             complement(48448..49260)
                     /locus_tag="VVR43_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6149022.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            49450..50868
                     /locus_tag="VVR43_000624"
     CDS             49450..50868
                     /locus_tag="VVR43_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU6149023.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIYWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            50921..51628
                     /locus_tag="VVR43_000625"
     CDS             50921..51628
                     /locus_tag="VVR43_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6149024.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGISIVVLVLFIIGARKTQLASFNFSFFRTKDLARLGLSYLVIICSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGLVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            51723..52703
                     /gene="folP"
                     /locus_tag="VVR43_000626"
     CDS             51723..52703
                     /gene="folP"
                     /locus_tag="VVR43_000626"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU6149025.1"
                     /translation="MVKSLEGVTDMLSKTNHAKTAICGIINVTPDSFSDGGQFFTLEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEIEEEIQRVVPVIKAIRKESDVLISI
                     DTWKSQVAEAALAAGANLVNDITGLMGDEKMAHVVANAGAKVVIMFNPVMARPQHPSS
                     LIFPHFGFGQAFTEEELADFEKMPIEELMEAFFERALARAEEAGIAPENILLDPGIGF
                     GLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFHNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            52705..54027
                     /locus_tag="VVR43_000627"
     CDS             52705..54027
                     /locus_tag="VVR43_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU6149026.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVIHI
                     GGTNGKGSTIAFLKNMLEKLGLRVGVFSSPYLIHYTDQISINGESIPEARLEALMADY
                     QSLLEGESATNLQGTTEFEIITAIAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVTLLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGADYHVSHQESVVTGEVFDYTSAIRQGRFQTGLLGLHQIENAGMAIALLDTFCQE
                     VGRKLPANILIAQALEETRWPGRLEVVSRNPLMILDGAHNPHAIKALLATLQERFADY
                     SKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFDDSRATDESVLEEAAKSRNLSYQG
                     WQDFLEQKLTDKKEEKKTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            54008..54562
                     /gene="folE"
                     /locus_tag="VVR43_000628"
     CDS             54008..54562
                     /gene="folE"
                     /locus_tag="VVR43_000628"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU6149027.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            54605..55417
                     /gene="folK"
                     /locus_tag="VVR43_000629"
     CDS             54605..55417
                     /gene="folK"
                     /locus_tag="VVR43_000629"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU6149028.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(55462..55779)
                     /locus_tag="VVR43_000630"
     CDS             complement(55462..55779)
                     /locus_tag="VVR43_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU6149029.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            56136..56582
                     /gene="rplM"
                     /locus_tag="VVR43_000631"
     CDS             56136..56582
                     /gene="rplM"
                     /locus_tag="VVR43_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU6149030.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            56602..56994
                     /gene="rpsI"
                     /locus_tag="VVR43_000632"
     CDS             56602..56994
                     /gene="rpsI"
                     /locus_tag="VVR43_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU6149031.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(57256..57678)
                     /locus_tag="VVR43_000633"
     CDS             complement(57256..57678)
                     /locus_tag="VVR43_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6149032.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            57825..58001
                     /locus_tag="VVR43_000634"
     CDS             57825..58001
                     /locus_tag="VVR43_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149033.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            58402..60615
                     /locus_tag="VVR43_000635"
     CDS             58402..60615
                     /locus_tag="VVR43_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU6149034.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFATEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(60837..61313)
                     /locus_tag="VVR43_000636"
     CDS             complement(60837..61313)
                     /locus_tag="VVR43_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU6149035.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINTFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            61536..64740
                     /locus_tag="VVR43_000637"
                     /pseudo
     CDS             61536..64740
                     /locus_tag="VVR43_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
     gene            65088..65473
                     /gene="tnpA"
                     /locus_tag="VVR43_000638"
                     /pseudo
     CDS             65088..65473
                     /gene="tnpA"
                     /locus_tag="VVR43_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(65852..66481)
                     /locus_tag="VVR43_000639"
     CDS             complement(65852..66481)
                     /locus_tag="VVR43_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU6149036.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(66491..67492)
                     /locus_tag="VVR43_000640"
     CDS             complement(66491..67492)
                     /locus_tag="VVR43_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU6149037.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(67523..68164)
                     /locus_tag="VVR43_000641"
     CDS             complement(67523..68164)
                     /locus_tag="VVR43_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU6149038.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKIIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(68183..68998)
                     /locus_tag="VVR43_000642"
     CDS             complement(68183..68998)
                     /locus_tag="VVR43_000642"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU6149039.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT        20584 a        12480 c        15413 g        20573 t
ORIGIN      
        1 tagagtaaaa ttctctacaa aaagaagaat agcctatttt actattcttc cgagtgattt
       61 caatttcttt ggggaaatat ggagatactt tttaaatact ttggcaaaat atttatagtc
      121 tgaaaatcca acttggtcag agatagcgct taaaggggag ttgggagatt cagccatctt
      181 atctatagct tgtttcaggc gatattgtaa gatatattca tttagagtca tggggaagtc
      241 ttctttgata accttatata gatgcttgtt atctgcaaat agctagagca tttcaaggaa
      301 ataaactaga aataacaatt aatatggtgg ttcagaaata ccttttgata atcaataaga
      361 tcttcaggat gaagtgcgtt gactccatcc atttcatatt tccgatttaa taaacgatat
      421 ttgttttcac caaattgatg aaaagggagt agttgaactt ggtcgatatt taatgagtta
      481 aatagagtag cgaatttttc tgcatcctct aaactattgt taaaattagg aataactggg
      541 attcttaaaa cgatagtttt attttgagaa aaagcataat gaatgttttt aataatcatt
      601 tgattaaaaa ccccagtcac ttttttatgt tttatagaat tataatgttt taggtctgtg
      661 tagataaaat ccacatattg aattaaatca ataaattttt catgatcaac aaaggcagta
      721 gtttcaatgg cagtgtgtat gtgatgttct ttagctgatt ttaagatggc tttagcaaat
      781 tcaaactgag caaatatttc acctcctgat aaagttaaac ctccaccgga ttcttcgtaa
      841 aattctttgt cttttaatac ctctgtaata atttcttcta cagtcttttc ttcaccgact
      901 aaggtgaatt tctctcgttg agcatctttc attttttcag gtttcattct ttgagattca
      961 ggattagaac accatggaca gcgcagagga catcctttta aaaaaacagt tgtacgaata
     1021 cccgggccgt catgaattga aaagtgttga atattaaaaa taattccttt agatatttcc
     1081 ataagagttc ctcctcttca taagtctatc ctatcacaaa aacgaaagaa aaacaattac
     1141 gaacgaaagt ttaatttgtt gttttttgct ttttattttg gtagaataaa acggaggtgt
     1201 aaaatgaaaa gattggaaca aattattaaa ttagtatcag aatatgaaaa gatcgacgtt
     1261 aatacattat cggaaaaatt aaatgtatcg aaagtaacga ttagaaaaga tttagataaa
     1321 ttagagtcaa aaggtttatt acacagagag catggatatg ctgtattaaa tagtggagat
     1381 gacttaaatg tacgtttgtc aattaattat gaaattaaga gaaaaattgt tcaggaagca
     1441 gtaaaattgg tgtcagataa tgaaacaata atgatagaat ctggatcgac ctgtgcttta
     1501 cttgctgagg aaatttgcaa gcaaaaaaga aatgttacga ttgtaacaaa ttcatttttt
     1561 atagcaaatt ttgtgagagc ttatgattca tgtcgtatta ttgttcttgg tggagagttt
     1621 cagaaggatt cacaggttac tgtgggacct ttattaaaag aaatgataca gacttttcat
     1681 gtgcatcaag cttttgttgg gacagatggt tacgataaag agatgggctt tacaggaaaa
     1741 gatttaatgc gcagtgaggt agttcaatat atttcagcag cgtcggataa agtcattgta
     1801 ctaactgact caagtaaatt tgataaaagg ggtacagtaa gaagatttgc tttaagtcaa
     1861 gtctatgaag taataacaga cgaaaaactt tctaaacaaa atatagctac attagaaaat
     1921 gctgggataa tggttaaggt agtttcgtaa gaggttaagt gtatgaatca agataggaat
     1981 aaactgctct ctaaaattgc ttatctgtat tatattgaaa acttaaatca gtcacaaata
     2041 gcagcaaaat taggaattta tagaacctct attagtagaa tgttaacaga agcaaggaat
     2101 gcaggaattg ttaaaattga aatagagaat tttgatacca atatgtttaa gttggaaaat
     2161 tatgtaaaag aaaaatatgg tctggaaagt ttagaaatta ttccaaatga atttgatgat
     2221 aatccaacaa ttttatctga aagaatttct caagttgcag caggtgtcct taggaatcta
     2281 attgatgata atatgaaaat tggcttttct tgggggaaaa gtttaagtaa tttagtagat
     2341 ttaattcaca gtaaaagtgt ccgaaatgtt cacttctatc ctctagcagg tggtcctagt
     2401 cacatacacg ctaaatacca tgtgaataca ctgatttatg aaatgtctag aaaatttcat
     2461 ggagagtgta catttatgaa tgcaacgatt gtgcaagaaa ataaattgtt agcagatggt
     2521 attttgcaat caagatattt tgaaaatttg aaaaatagtt ggaaagattt agatatagct
     2581 gtagtcggaa ttggtgattt tagcaataaa ggaaagcatc aatggttaga catgcttaca
     2641 gaggatgact ttaaagaatt gaccaaagtt aaaactgtag gagaaatttg ttgtcgattt
     2701 tttgattcaa aaggtaaaga agtctatgaa aacttacagg aaagaacgat agcaatctct
     2761 ttggaagatt taaaaaatat tcctcaaagt ttagctgttg cttacggtga tacgaaagta
     2821 tcttcgattc tttctgtctt gcgtgctaat ttagtaaatc atttgattac agacaaaaat
     2881 acaattttaa aagttttgga agaagatggg gatttgactt ttagagagat tctaggtgag
     2941 tgaaaatgat agactgattc agtttatcgt ttttcttttt agttgattgc acatttgtgc
     3001 ttatataaac aaaaatagtt tatctgttgt ttttggattg acaactttat tatgtagttg
     3061 tattctatag ttacaaaaga aaattttaaa atttcaaatg aaaaaagctt tttacatagt
     3121 gaaatgagga ggaatttatg gaaattattg ttccagatca aattatcatg ggtttaattt
     3181 tatatgctgg cgatgcgaaa caacatattt ataaagcatt agattacata aagaacggta
     3241 catgtgaacg atgtgaagaa gaaatccagt tagctgatgc agccttatta gaagctcata
     3301 atctacaaac aaaattcttg gcacaggaag cgtctggtac aaagacagaa attacagctc
     3361 tctttgttca ttcacaagat catctcatga ctagtatgac ggagattaat ttaatcaaag
     3421 aaattattag tttgagaaaa gaacttcata aaaaataata ctagagtatt atcattgtta
     3481 ttaacataga ggaggaaaac ataatggtga agattggttt gttttgtgca gcaggttttt
     3541 ctactggtat gcttgtaaat aatatgaaaa ttgcagcgca atctagtgga gttgaggcag
     3601 aaatagaggc gttttctcag tctaaattag cggattatgc gccaaatata gatgttgcac
     3661 tattgggtcc acaagttgct tatacattag ataaatcaaa agaaatttgt gataagtgtg
     3721 atgttccgat agctgttatt ccgatgatgg actatggtat gttagatggg aaaaaagtat
     3781 tagatttggc cctatctttg attagtgggt aagaaaagga gatttattat gtcaaagatg
     3841 gatgttcaga aaatcattgc accgatgatg aagtttgtga atatgcgtgg cattatagct
     3901 ctaaaagatg ggatgttagc aattttgcca ttgacagtag ttggcagttt gttcttgatt
     3961 atgggacaat tgccgttcga aggattaaat aagagcattg ctagtgtttt tggagctaat
     4021 tggacagagc cgtttatgca agtatattca ggaacttttg ctattatggg tctaatttct
     4081 tgtttttcaa ttgcctattc ttatgctaag aatagcggag tagaggcttt accagctgga
     4141 gttctatctg tatctgcatt ctttattttg ctaagatcat cttatatccc taaacaaggt
     4201 gaggcgattg gggacgctat tagtaaagtt tggtttggag gccaaggaat tatcggtgct
     4261 atcattatag gtttggtagt aggaagtatt tataccttct ttataaagag aaaaattgtt
     4321 attaagatgc cagaacaagt tccacaagct attgccaaac agtttgaagc aatgattcca
     4381 gcatttgtaa ttttcttatc ttctatgatt gtatatattt tagcgaagtc attgactaat
     4441 ggcggaacat tcatagaaat gatttattct gctattcaag ttccgttgca aggtttaact
     4501 ggatctttgt atggtgctat tggaattgca ttctttatat catttttgtg gtggtttggt
     4561 gttcatgggc aatcggtagt aaatggagta gtgacagctc tgcttttatc taatcttgat
     4621 gctaataaag ctatgttagc ctctggtaat ctatcattag aaaatggtgc acatattgtt
     4681 actcaacaat ttttagattc atttttaatt ctatcaggtt cagggattac gtttggtctt
     4741 gtagttgcca tgctttttgc agcaaaatca aaacaatacc aagccttagg aaaagttgca
     4801 gcttttccag caatatttaa cgtaaatgag ccagttgtat ttggatttcc gattgtcatg
     4861 aatccagtta tgtttgtacc tttcattctt gttcctgtac ttgcagctgt gatagtatat
     4921 ggagctattg caacaggttt catgcaacca ttctcagggg taacattgcc ttggagtaca
     4981 ccagctattc tatcaggatt tttggtgggt ggatggcaag gtgttgtgac tcagttatta
     5041 gtattggcga tgtctacaat ggtttacttt ccattcttta agatacaaga tcgtttagct
     5101 tgccaaaatg aaatcaaaca atcttagagg tatttgtgtg ttactgttaa actcacacat
     5161 ttgtgctaaa aattagagag ttaaaatttt tctagttaaa agcttgaaaa tttctataaa
     5221 aatcggtatt atattttcga aagaaataaa aacattttcg aaagaaaggt gcttacgatg
     5281 gtaaatacag aagtagcaag aacaacaatc aagacagaat attttggcag ccttactgaa
     5341 aggatgaaca aatatcgaga agatgtttta aataaaaaac cttatattga tgctgagaga
     5401 gcagttctag caacacgcgc ctatgaacga tacaaggaac aacctaatgt cctaaaacgt
     5461 gcatatatgc tgaaagaaat tttggaaaat atgtctatct atattgaaga agaatctatg
     5521 attgcgggaa atcaagcttc ttccaataaa gatgctccta tttttccgga atatacgcta
     5581 gaatttgttc tcaatgagtt ggatcttttt gaaaagcgtg atggagatgt tttctatatt
     5641 acagaagaaa caaaagaaca acttagaagt attgctccgt tttgggaaaa taataattta
     5701 cgtgctagag ctggtgcctt attacctgaa gaagtgtctg tttatatgga aacaggattc
     5761 ttcggtatgg aaggtaagat gaattctgga gatgctcact tagcagttaa ctatcagaaa
     5821 cttttgcaat ttggtttaag aggttttgaa gagcgggctc gtaaagcgaa ggtagctcta
     5881 gatttaacag atccagcaag tattgataaa tatcattttt acgactctat atttatcgta
     5941 atcgatgcta ttaaagtata tgcaaagcgc tttgttgctc ttgctaaaag tttagccgaa
     6001 aatgcaaatc ctaaacgtaa gaaagaatta cttgagattg cagatatttg ctctagagtc
     6061 ccatatgaac cggcaactac ttttgcagaa gctattcaat cagtttggtt tattcaatgt
     6121 attttacaaa ttgaatctaa tggccactct ctttcatatg gccgttttga tcaatatatg
     6181 tatccatata tgaaggctga tttagaaagt ggtaaagaaa cagaagatag cattgttgaa
     6241 cgtctgacaa atctttggat taagacaatt acaattaata aggttcgcag tcaatcacat
     6301 acattttctt cagcaggaag tcctttatat caaaatgtta caattggtgg acagactcga
     6361 gataagaagg atgctgttaa cccattatct tatttggtat taaaatcagt tgcacaaacc
     6421 catctaccgc aacctaatct aactgtacgt taccatgcag gtttagatgc tcgtttcatg
     6481 aatgagtgta ttgaagtgat gaaacttggt tttggtatgc ctgcatttaa taatgatgag
     6541 attattattc cttcttttat tgcaaaagga gtattggaag atgatgctta tgattacagt
     6601 gccattggat gtgttgaaac ggcagttccg gggaaatggg gctatcgttg cacaggtatg
     6661 agttatatga acttccctaa ggttctactt atcacgatga atgatggaat tgatccggct
     6721 tcgggtaaac ggtttgcacc aagctttggt cattttaagg atatgaagaa cttttctgaa
     6781 ttagaaaatg cttgggataa aacactaaga tatttgacac gaatgagtgt tattgttgaa
     6841 aattctattg atttatcatt ggaacgagaa gttcctgata ttctatgttc agcattgact
     6901 gatgattgta ttggtcgtgg aaaacacctt aaagaaggtg gagcagtata tgattatata
     6961 tcaggattgc aagttggaat tgcaaatttg tcggattcat tagctgcaat taaaaaattg
     7021 gtgtttgagg aagaacgtat aagcccaagt cagctttggc atgcactgga aacagattat
     7081 gccggagaag aaggtaaggt cattcaagaa atgttgattc atgatgcacc taagtatggt
     7141 aatgatgatg attatgctga caaattggtt actgctgctt atgacattta tgttgatgaa
     7201 attgctaaat atcctaatac acgttatgga agaggtccaa ttggaggaat tcgttattca
     7261 ggaacatctt ctatctcagc caacgtaggg cagggacgtg gaacattagc aactccagat
     7321 ggacgcaacg cgggtacacc gttagcagag ggttgttcac catcacataa tatggatcaa
     7381 cacggcccta catctgtttt aaaatctgtt tcaaaattac caacagatga aatcgtaggt
     7441 ggggttctct taaatcagaa agtaaatcct caaacgttag ccaaagaaga agataaatta
     7501 aaactaattg ctttgttacg aacattcttt aatcgtttac atgggtacca tattcaatac
     7561 aatgttgttt ccagagagac gctgattgac gctcagaaac atcctgaaaa acacagagac
     7621 ttaattgttc gtgttgcagg atactctgca ttcttcaatg ttctttctaa ggcaacccaa
     7681 gatgacatta taggacgtac tgagcatact ttgtaaaata aagaggttct ttttatggaa
     7741 tttatgcttg acacattaaa tttagatgag attaaaaagt ggtctgaaat tttgccgcta
     7801 gctggggtaa cttcaaatcc cactattgca aaaagagagg gttctattaa tttttttgaa
     7861 cgaatcaaag atgtaagaga attgattggc tctacaccct ctattcatgt tcaggtgatt
     7921 tctcaagatt ttgaaggcat cttaaaggat gctcatgaaa ttcgaagaca agcaggagat
     7981 gatatattta tcaaagtacc tgttactcca gctggattac gtgcaataaa ggtgctaaaa
     8041 aaagagggct accatatcac tgcaacagct atttatacag ttattcaggg attattagct
     8101 atcgaagcag gagcggatta cctagctcca tattataata gaatggaaaa tctgaacatt
     8161 gattcaaatt ctgtcattcg tcaattagct cttgctattg atagacagaa ctctcctagt
     8221 aagattttag ctgcatcctt taaaaatgta gcacaagtaa ataatgcttt agctgcaggt
     8281 gcgcatgctg ttacagcagg agcagatgtt tttgaatcag ctttcgccat gccatctatc
     8341 caaaaggcgg ttgatgattt ttctgacgat tggtttgtta ctcaaaatag tcgttccatt
     8401 tagatagaga ggaaatacat atgagaattt ttgctagtcc ttctagatat attcaggggg
     8461 aaaatgcctt gtttgaaaat gccaaatcaa ttttggattt gggaaattac ccgattctat
     8521 tatgcgatca gttggtttat gatattgttg gaaaacgatt tgaagattat ctacataggt
     8581 atggtttcca tattgttctg gcgctattta atggtgaagc ttctgacaat gaaatcaatc
     8641 gagttgttgc cttggctgag aaagaaaatt gtgatagtat tatcggtctt ggtgggggaa
     8701 agacgattga tagcgcaaaa gctattgcag atttgattga aaagcctgtt attattgctc
     8761 caacaattgc atcgaccgac gcacctgtat ctgctttatc tgttatttat acagatgaag
     8821 gtgcatttga tcattatcta ttttattcta aaaatccaga tttagttttg gttgatacaa
     8881 aagttatttc acaagcccct aagcgtttat tagcgtctgg tattgcagat ggtttagcaa
     8941 cttgggttga ggcgcgtgcg gttatgcagg caaatggaaa aactatgttg ggacaacagc
     9001 aaacattggc tggagttgca attgcgaaga aatgtgaaga aacgctgttt gcagatggtt
     9061 tacaggctat ggcagcttgt gaagctaaag tggtgacacc agcattagaa aatattgttg
     9121 aagctaatac tttattgagt ggtctaggtt ttgaaagtgg aggattagct gcggcgcatg
     9181 caattcataa tggttttact gcattgacag gtgacattca tcatttaaca catggtgaaa
     9241 aagtagctta tggaacttta gtacaactat tattggaaaa tagacctaaa gaagaacttg
     9301 ataagtatat tgagttttac aaaaaaattg gtatgccaac aactctaaaa gaaatgcatt
     9361 tggatcaagt tggatatgat gatttaataa aagttggtaa acaagcaact atggagggtg
     9421 agacaattca tcagatgccg tttaagattt cgccttcaga tgttgctcaa gctattatcg
     9481 ctgtagatgc ctatgtaaat tcaaaataaa caataaggac tactgttttc caaatggtag
     9541 tcttttattg atccctgtat tgaattctat agaagattga aataggatga gaacaaatcg
     9601 attgggaaag taaaattaat ttctataaat gttttagcaa ttgtttcgta ctatttcaga
     9661 ttcagtctac tatacgttct tcataaatca aaaagcgaca taggtagtcg gctatttatt
     9721 gtgaatacat taattagcat tccagtttta tcttcggtct aaaataagta ttttgtgcta
     9781 tacgagataa gcttcttgac ttactccttg atttactgca taacaatggg ataaaaagtg
     9841 ggagatagag caattcatag tcatcaaaat taatgagata cagtatacag ttttttcttt
     9901 aaacacattt caaattccct caaaaatggt ataatagtaa catcacaaaa ttggagagag
     9961 accatgagtt tttataatca taaagaaatt gagcctaagt ggcagggcta ctgggcagaa
    10021 catcatacat ttaagacagg aacagatgca tcaaaaccta agttttatgc gcttgatatg
    10081 ttcccttatc cgtctggagc tggtctgcac gtaggacacc cagaaggtta tactgcaacc
    10141 gatatcctca gtcgttacaa acgtgcgcaa ggctacaatg tccttcaccc aatgggttgg
    10201 gatgcttttg gtttgcctgc agagcaatac gctatggata ctggtaatga cccagcagaa
    10261 tttacagcgg aaaacattgc caacttcaaa cgtcagatca atgcgcttgg attttcttat
    10321 gactgggatc gtgaagtcaa cacaacagat ccaaactact acaagtggac tcaatggatt
    10381 ttcaccaagc tttacgaaaa aggcttggcc tatgaagctg aagtgccagt aaactgggtt
    10441 gaggaattgg gaactgccat tgccaatgaa gaagtgcttc ctgacggaac ttctgagcgt
    10501 ggaggctatc cagttgtccg caaaccaatg cgccaatgga tgctcaaaat cacggcttac
    10561 gcagagcgct tgctcaatga cttagatgaa ctagattggt cagagtctat caaggatatg
    10621 caacgcaact ggattggtaa atcaactggt gccaatgtaa ctttcaaagt aaaaggaaca
    10681 gacaaggaat ttacagtctt tactactcgt ccggacacac ttttcggtgc gactttcact
    10741 gtcttggctc ctgaacatga attagtagac gctatcacaa gttcagagca agcagaagct
    10801 gtagcagact ataaacacca agccagcctt aagtctgact tggttcgtac agaccttgct
    10861 aaggaaaaaa ctggtgtttg gactggtgct tatgccatca accctgtcaa tggtaaggaa
    10921 atgccaatct ggattgcgga ctatgttctt gctagttatg gaacaggtgc ggttatggct
    10981 gtgcctgccc acgaccaacg tgactgggaa tttgccaaac aatttgacct tccaatcgtc
    11041 gaagtacttg aaggtggaaa tgtcgaagaa gctgcctaca cagaggatgg cctgcatgtc
    11101 aattcagact tcctagatgg attgaacaaa gaagacgcta ttgccaagat tgtggcttac
    11161 ttggaagaaa aaggctgtgg tcaggagaag gttacctacc gtctccgcga ctggctcttt
    11221 agccgtcaac gttactgggg tgaaccaatt ccaattattc attgggaaga tggaacttca
    11281 acagctgttc ctgaaactga attgccgctt gtcttgcctg tcaccaagga catccgtcct
    11341 tcaggtaccg gtgaaagtcc actagctaac ttgacagact ggcttgaagt gactcgtgaa
    11401 gatggtgtca aaggtcgtcg tgaaactaac accatgccac aatgggctgg ttcaagctgg
    11461 tactaccttc gctatattga cccgcacaat actgagaaat tggctgatga ggacctcctc
    11521 aaacaatggt tgccagtaga tatctacgtg ggtggtgcgg aacatgctgt acttcacttg
    11581 ctttatgctc gtttctggca taaattcctc tatgacctcg gtgttgttcc gactaaggaa
    11641 ccattccaaa aactctttaa ccaagggatg attttgggaa caagctaccg tgaccaccgt
    11701 ggtgctcttg tgacaaccga caaggttgaa aaacgtgatg gttccttctt ccatgtagaa
    11761 acaggggaag agttggagca agcgccagcc aagatgtcta aatcgctcaa gaacgttgtt
    11821 aacccagacg atgtggtgga acaatacggt gccgataccc ttcgtgttta tgaaatgttt
    11881 atgggaccac tcgatgcttc gattgcttgg tcagaagaag gtttggaagg aagccgtaag
    11941 ttccttgacc gagtttaccg tttgattaca agtaaagaaa tccttgcgga aaacaatggt
    12001 gctcttgaca aggcttacaa cgaaacagtc aaagctgtta ctgagcaaat tgagtctctc
    12061 aaattcaaca cagctattgc ccaacttatg gtctttgtca atgctgctaa caaggaagat
    12121 aagctttata ttgactatgc caaaggcttt attcaattga ttgcaccatt tgcacctcac
    12181 ttggcagaag aactctggca aacagtcgca gaaacaggtg agtcaatctc ttatgtagct
    12241 tggccaactt gggacgaaag caaattggtt gaagatgaaa ttgaaattgt cgtccaaatc
    12301 aaaggaaaag ttcgtgccaa actcatggtt gctaaagatc tatcacgtga agaattacaa
    12361 gaaatcgctt tagctgatga aaaagtcaaa gcagaaattg acggtaagga aatcgtgaaa
    12421 gtaattgcgg taccgaataa actcgttaat atcgtcgtta aataacgagt ttattagctc
    12481 tatctgccac cttcaatagt ccactggact attgaagcca actaaattag ttaacattgt
    12541 tgtgaaataa aaagaagtaa ctctagagta tgaactttag agttactttt agaataggtc
    12601 agaatgaata gattagtgaa cgatagcagg aagtgtgaaa ttttattatt taagatttct
    12661 attattgtag tgtcagttat agtattagta atgtcaatag tgggtgcata ttattttaaa
    12721 aattgtcttt gggacaagga aagtttaaat ttgacactca ctttagacac tctctttgca
    12781 gtttttatta ctttctttag tttttcaaat gataaatcaa gcaatatttt tggaatatct
    12841 ccaaatgaaa ttataaggac acagtctgaa gtgtatcaat ttttatttac aaaatctttt
    12901 gcaactctat taatagtgac aaatttgtta tccattattc attattttgg agccaaaaat
    12961 ttaatagttt cttttaatga aacttatcct cgtattcaat ccagtgttgg tatcatgtgg
    13021 ctaccactgt ttggtattct gataatctat tttatttggc tcttaataga gggattaaaa
    13081 tatatcagaa aaataaatta tattattcaa aatagggaaa taatctattt ttattcgcag
    13141 gtaaaagttg tagataaact tactgattct gaatcgaaaa aatacggtga atatattgat
    13201 ttgtacgaat cgtgtcgtca gaacaattta agtgttctac ttaactttct tcaaaattcg
    13261 gatgataaac gaggagttat tgctagtaac tcagtgagaa ttatgtttga atctttggat
    13321 aaagcagacc aaattgcggc cctgaatatt tgtagaaact atgtagcacg agaaaatgtt
    13381 ttaaataaag aagatgcaga aaaattgtta aatgaaattg ataaaaaact tgaaattagc
    13441 agataggaca attcaaatag agttgagtaa aaagtttgaa aagtgaaaca aggagaaagc
    13501 tatgccagta aatgaatatg gtcagatgat tggtgagtca atggaaggtt atacacccgg
    13561 tgcactgcct tctattgatt tcttagaagg gcgttatgct aggatagagg ctctctcggt
    13621 agaaaaacat gcggaggatt tgctagctgt ttatggcccg gatactcctc gggagatgtg
    13681 gacctatctt tttcaggagc cagtagcaga tatgggggag ctggttagcc ttttaaatca
    13741 gatgttggct cgtaaggacc gtttttacta tgcaatcata gacaaggcga ctggtaaggc
    13801 tttgggaact ttttctctca tgcgcattga ccagaataac cgagtaatag aagtcggagc
    13861 agtcactttt tctccagagc taaggggtac acggatagga actgaggctc agtatctcct
    13921 agctcgctat atttttgagg agctaaacta tcgtcgctac gagtggaaat gcgatgcctt
    13981 aaatctgcca tccagacgag ttgcggagcg tttgggattt gtctatgaag gaaccttccg
    14041 ccaggcggtg gtttataagg ggcgtacgag agatacggat tggttgtcta tgattgatat
    14101 ggactggcct caagtcaaag atcgtttgga aacatggctg cgtcctgaaa attttgataa
    14161 aaatggacag cagtacaaga gcttgagaga actttaagag gtgttgagat gattactatt
    14221 aaaaagcaag aaattgtcaa gctagaggat gttttgcatc tctatcaggc tgtcggttgg
    14281 acaaattata cccatcaacc agagatgctg gagcatgcct tatcgcattc attagtaatt
    14341 tatctggcac ttgatggtga tgctgtggtg ggcttgattc gtttggttgg agatggattc
    14401 tcatcagttt ttgtacagga tttgattgtt ttaccaatct atcagcgtca agggattggt
    14461 agtgccctaa tgaaagaggc cttaaaagat tacaaagatg cttatcaagt ccagctggtg
    14521 acagaagaga cagaaaaaaa cgtgggattt tatcgttcta tgggctttga aatcttatcc
    14581 acctataatt gtatagggat gacttgggcg aatcgagaaa aataacaaaa cttgtttttt
    14641 cttaagcaaa atttaaggat ggtctagtat tatatagtca ttaaataaag acctcctaac
    14701 tttatttaat aaaatcctaa acttttttca tcacaatctc ctaatgaagc cacccaatca
    14761 ggtggctttt ttgcgtggtg aggtgctggt gatagaaatt ttttgcaaaa tagtaaaatt
    14821 ttagaaaagt taagctagtt ttaagtttcg tcttgtatca tgtagttatt aaataaagac
    14881 ctcctaactt tatttaataa aatcctaaac ttttcttttt cataataatc tcccttaact
    14941 ccacccaatc aggtggagtt ttttagctct atttcaggct tttggggact attctaaaaa
    15001 taatttttcg atatttttcg gtatttttcg gattttggtc ggggaattgg cggggacttt
    15061 tttagcgaat ataactaaga aataggtctg tggtcgcttc agctagttca aactcaattt
    15121 gattgtaagt gactgttaat tgaagaactg gaactactgt aataatgatt ttgcttgtct
    15181 agtagtggcg tattaaatga gaagtgacat gtaagattgt ctcttcgttt acgaaatcaa
    15241 aatttctatg aaattgatag aatccctaac gttctcttaa tcttaaccgt cttgtcgtac
    15301 agcggttgaa gaaaatgtaa acctttgaca aaattcgtga actatgggat aataaaaagg
    15361 aattgagtac tagttctata tcataggcta gaaaagaccc caagctcacg accaaataag
    15421 cttggggtct tttttgacac tatttgtcct tgtttagcca tttatcgact atacgaagaa
    15481 cgacaccgac cacaattggt ccgatgatag ttttgagtac taattccatc atgggctatc
    15541 tcacctcctt tcgtaggcgg tgtagcagtg tcgtagaata ttataccaca taagtgctaa
    15601 acttaggagt cacccaatca ggtggctttt ttgtttgtgg cttggttttt tgatataata
    15661 gagccatgag tagaatttta gataatgaga taatggggga tgaggagtta gtagaacgca
    15721 cgctccgtcc tcagtattta cgtgaatata ttgggcagga taaggttaag gaccagcttc
    15781 aaatctttat agaagctgcc aaaatgcgag atgaagcgct ggatcatgtc ctcttatttg
    15841 ggcctccagg tttggggaaa acaaccatgg cttttgtcat tgccaatgaa ctgggagtca
    15901 atctcaagca aacgtctggt cctgttatcg aaaaagcggg tgatttggta gcgattttga
    15961 atgagttaga gcctggagat gtcctcttta ttgacgagat tcatcgctta cccatgtcag
    16021 tggaagaagt gctttatagt gccatggagg acttctacat cgatattatg attggggctg
    16081 gtgaaggcag tcgcagtgtt catttggagt tgcctccttt taccttgatt ggtgcgacga
    16141 ctcgggctgg tatgctctca aatccactac gggcacgttt tgggattaca ggtcatatgg
    16201 agtattatgc ccatgctgac ttgacagaaa ttgtcgagcg gacggcagat atttttgaga
    16261 tggaaatcac tcatgaggca gcatctgagt tggccctacg tagtcgtgga acccctcgta
    16321 ttgccaatcg tctcctcaag cgcgtgcgcg attttgccca gataatgggg aatggggtaa
    16381 tcgatgatat tattaccgat aaggctttga ctatgctgga tgttgaccat gaaggtttgg
    16441 actatgtgga tcaaaaaatc cttcgtacca tgattgagat gtacagtgga ggacctgttg
    16501 gtctaggaac tctttctgtc aatatcgccg aagagcgtga gacagttgaa gacatgtatg
    16561 agccttactt gattcaaaaa ggttttatca tgcggacacg gtctggacgg gtggcgactg
    16621 ctaaggcata tgagcactta ggttatgaat acagtgaaaa ataagcaaga aatcttagag
    16681 gcttttagag aaaatccaga tatgatggcc attctgacga tcatccgaga ccttggtttg
    16741 aaagactcgt agttggcagc aggttctgtc agaaatttca tctggaatct tttgtcagac
    16801 aaatcccctt ttgatcatga aacagatata gatgtgattt tctttgatcc agatttttct
    16861 tatgaggaaa ccttattact ggagaaaaag ctgagagagg attttcctca gtaccagtgg
    16921 gaattgaaaa atcaggtcta tatgcatcag cacagtcctc acactgcttc ctataccagt
    16981 tctcgtgatg ctatgagtaa gtatccagaa cggtgtacgg cagttggact gcgcttgaat
    17041 gaagaatcag attttgaact ctatgcacct tatggtttgg aggatatttt gaattttcaa
    17101 gttcgtccaa ctcctcattt cttagaaaat gaagaccgaa tggaactcta tcaaacacgt
    17161 ttatccaaga aaaattggca ggagaaatgg aaaaatttga tttttaaaaa tacttaagga
    17221 aactttaagc tagggagtgt acactaagtt cataagttaa gaagacctta acttaaactc
    17281 ctaaaacttt ttcataataa tctccctata aaaataaagt cgcccaatca ggcggcttat
    17341 ttttttgaaa aatgggcatg gtgcctgaga ataaatagct tagtgataga agaaaatggg
    17401 gaaatatggt ataatgaaac gatagatttt tgaataggaa taagatcatg tttggatttt
    17461 ttaagaaaga taaggctgtg gaagtagagg ttccgacaca ggttcctgct catatcggca
    17521 tcatcatgga tggcaatggc cgttgggcta aaaaacgtat gcaaccgcga gtttttggac
    17581 ataaggcggg catggaagca ttgcaaaccg tgaccaaggc agccaacaaa ctgggcgtca
    17641 aggttattac ggtctatgct ttttctacgg aaaactggac ccgtccagat caggaagtca
    17701 agtttatcat gaacttgcca gtagagtttt atgataatta tgtcccggaa ctacatgcga
    17761 ataatgttaa gattcaaatg attggggaga cagaccgcct gcctaagcaa acctttgaag
    17821 ctttaaccaa ggctgaggaa ttgactaaga acaacacagg attgattctt aattttgctc
    17881 ttaactatgg tggacgtgct gagattacac aggcgcttaa gttgatttcc caggatgttt
    17941 tagatgccaa aatcaaccca ggtgacatca cagaggaatt gattggtaac tatctcttta
    18001 ctcagcattt gcctaaggac ttacgagacc cagacttgat tatccgtact agtggagaat
    18061 tacgtttgag caatttcctt ccatggcagg gagcctatag tgagctttat tttacggaca
    18121 ccttatggcc tgattttgac gaagcggcct tgcaggaagc tattcttgcc tataatcgtc
    18181 gtcatcgccg atttggagga gtttaggagg aaatatgacc caggatttac agaaaagaac
    18241 cttgtttgca gggattgccc tggctatttt cctaccaatt ttaatgattg ggggcctctt
    18301 gcttcagata gcaatcggaa tcatagccat gctagccatg catgaacttt tgaagatgag
    18361 aggtctagag accatgacga tggagggcct cttgaccctc tttgcaacct ttgcattgac
    18421 cattcccttg gagaattacc tgactttttt gccagttgat gggaatgtgg ttgcctatag
    18481 tgttttgatt tcaatcatgt taggaacgac cgtttttagc aagtcttata cgattgagga
    18541 tgcggttttc cctcttgcta tgagcttcta cgtgggcttt ggatttaatg ctttactaga
    18601 tgctcgtgtt gcaggtttgg acaaggctct cttagccttg tgtatcgtct gggcgacaga
    18661 cagtggtgcc tatcttgttg ggatgaacta tgggaaacga aagttagcac caagggtatc
    18721 gcctaataaa acccttgagg gtgccttggg tggtatttta ggagcaattt tagtaaccat
    18781 tatctttatg atagttgaca gtacagttgc tcttccatat ggaatttaca agatgtcagt
    18841 ctttgctatt ttctttagca ttgctggaca atttggtgat ttactagaaa gttcgatcaa
    18901 acgtcatttt ggtgttaagg attctgggaa atttatccct ggacatggtg gtgttttgga
    18961 tcgtttcgat agtatgttgc ttgtatttcc aatcatgcac ttatttggac tcttttaatc
    19021 aaaagacgga ggaaacgcta tgctcggaat tttaaccttt attctggttt ttgggattat
    19081 tgtagtggtg cacgagttcg ggcacttcta ctttgccaag aaatcaggga ttttagtacg
    19141 tgaatttgcc atcggtatgg gacctaaaat ctttgctcac attggcaagg atggaacggc
    19201 ctataccatt cgaatcttgc ctctgggtgg ctatgtccgc atggccggtt ggggtgatga
    19261 tacaactgaa atcaagacag gaacgcctgt tagtttgaca cttgctgatg atggtaaggt
    19321 taaacgcatc aatctctcag gtaaaaaatt gggtcaaaca gccctcccta tgcaggtgac
    19381 ccagtttgat tttgaagaca agctctttat caaaggattg gttctggaag aagaaaaaac
    19441 atttgcagtg gatcacgatg caacggttgt ggaagcagat ggtactgagg ttcggattgc
    19501 acctttagat gttcaatatc aaaatgcgac tatctggggc aaactgatta ccaattttgc
    19561 aggtcctatg aacaatttta tcttaggtgt tgttgttttt tgggttttaa tctttatgca
    19621 gggtggtgtc agagatgttg ataccaatca gttccatatc atgccccaag gtgccttggc
    19681 caaggtagga gtaccagaaa cggcacaaat taccaagatt ggctcacatg aggttagcaa
    19741 ctgggaaagc ttgatccaag ctgtggaaac agaaaccaaa gataagacgg caccgacttt
    19801 ggatgtgact atttctgaaa aggggagtga caaacaagtc actgttacac ccgaagatag
    19861 tcaaggtcgt taccttctag gtgttcaacc gggggttaag tcagattttc tatccatgtt
    19921 tgtaggtggt tttacaactg ctgctgactc agctctccga attctctcag ctctgaaaaa
    19981 tctgattttc caaccggatt tgaacaagtt gggtggacct gttgctatct ttaaggcaag
    20041 tagtgatgct gctaaaaatg gaattgagaa tatcttgtac ttcttggcaa tgatttccat
    20101 caatattggg atttttaatc ttattccgat tccagccttg gatggtggta agattgtgct
    20161 caatatccta gaagccatcc gccgcaaacc attgaaacaa gaaattgaaa cctatgtcac
    20221 cttggccgga gtggtcatca tggttgtctt gatgattgct gtgacttgga atgacattat
    20281 gcgactcttt tttagataat cgaggaatat tatgaaacaa agtaaaatgc ctatcccaac
    20341 gcttcgcgaa atgccaagcg atgctcaagt tatcagccat gctcttatgt tgcgtgctgg
    20401 ttatgttcgc caagtttcag caggtgttta ttcttatcta ccacttgcca accgtgtgat
    20461 tgaaaaagct aaaaacatca tgcgccaaga attcgaaaag attggtgctg ttgagatgtt
    20521 ggctcctgcc cttcttagtg cagaattgtg gcgtgaatca ggtcgttacg aaacctatgg
    20581 tgaagacctt tacaaactaa aaaaccgtga aaaatcagac tttatcttag gtccaactca
    20641 cgaagaaacc tttacagcta ttgtccgtga ttctgttaaa tcttacaagc aattgccact
    20701 caacctttat caaattcagc ccaagtatcg tgatgaaaaa cgcccacgta atggacttct
    20761 tcgtacacgt gagtttatca tgaaggatgc ttatagtttc cacgctaact atgatagttt
    20821 ggatagtgtt tatgatgagt acaaagcagc ctatgagcgt attttcactc gtagtggttt
    20881 agacttcaag gctattattg gtgacggtgg agccatgggt ggtaaggata gccaagaatt
    20941 tatggccatt acatctgctc gtacagacct tgaccgctgg gttgtcttgg acaagtcagt
    21001 tgcctcattt gacgaaattc ctgcagaagt gcaagaagaa atcaaggcag aattgctcaa
    21061 atggatagtc tctggtgaag ataccattgc ttactcaagt gagtctagct atgcagctaa
    21121 cttagaaatg gcaacaaacg agtacaaacc aagcaaccgt gttgtcgctg aagaagaagt
    21181 tactcgtgtt gcaacgccag atgttaaatc aattgatgaa gttgcagctt tcctcaatgt
    21241 tccagaagaa caaacgatta aaaccctctt ctacattgca gatggtgagc ttgttgcagc
    21301 ccttctagtt ggaaatgacc aactcaacga agtcaagttg aaaaaccact tgggagcaga
    21361 tttctttgac gttgctagcg aagaagaagt ggcgaatgtt gttcaagcag gatttggttc
    21421 acttggacca gttggtttgc cagagaatat taaaattatt gcagatcgta aggtgcaaga
    21481 tgttcgcaat gcagttgtcg gtgctaacga agatggctac cacttgactg gtgtgaaccc
    21541 aggccgtgat tttactgcag aatatgtgga tatccgtgaa gttcgtgagg gtgaaatttc
    21601 cccagatgga caaggtgtcc ttaactttgc gcgtggtatt gagatcggtc atattttcaa
    21661 actcggaact cgctactcag caagcatggg agcagatgtt ttggatgaaa atggtcgtgc
    21721 tgtgccaatc atcatgggat gttacggtat cggtgtcagc cgtcttcttt cagcagtgat
    21781 ggagcaacac gctcgcctct ttgttaacaa aacgccaaaa ggtgaatacc gttacgcttg
    21841 gggaatcaat ttccctaaag aattggcacc atttgatgtg catttgatta ctgtcaatgt
    21901 caaggatgaa gaagcgcaag ccttgacaga aaaacttgaa gcaagcttga tgggagctgg
    21961 ttatgaagtc ttgacagatg accgtaacga acgtgtcggt gttaaattta gcgatagtga
    22021 cttgattggt cttccaatcc gtatcactgt tggtaaaaaa gcggccgatg gcattgtaga
    22081 agttaagatc aaggcaactg gtgacaccat tgaggttcat gcagataacg tgcttgaaac
    22141 gcttgaaatc ctaagcaaga aataaaaact ataatcagaa gaaaaacaag gaaaaaatgt
    22201 aactagtttt taccttgttt tttctgtata atgggagaaa tgagtagata aagaggtaaa
    22261 tgttatgcta agatttccaa aggattttgt ctggggatcc tctacttctg gaccgcagac
    22321 agaaggacgt gtagctggtg acggtaaggg agacaatctc tgggattact ggttccaagt
    22381 ggagccaaat cgttactata atgggattgg ttcagataag acatcgactt tttatgaaaa
    22441 ttgggagcgg gatattgagc ttttgttaga gactggtcac acagtctttc ggacttctat
    22501 tcagtggtca cggatttttc cacaaggctg tggaaaagtc aaccctcaag gtgtggattt
    22561 ttatcgtaag gtctttgagg ctattaaggc taaaggaatt cgtctgttag tcaatctcta
    22621 tcattttgat ttaccttttg cccttcaaga ggatggtgat ggttgggaaa ataaggcgac
    22681 agtctcagcc tatgaagact atgctcgttt ttgttttgag acttatggag atttagtgga
    22741 tcaatggatt acctttaacg agcccatcgt tcctgtagaa tttggttatt tttatgatgc
    22801 ccattatcca cataaggtgg atgcagaggc agctgttaag gtagcctatc atacacaatt
    22861 ggccagcagc cgggctgtta aggcttgcca tgaacttttg cctgattcca agattgggat
    22921 tgtcctcaac ttgacaccgg cttatccacg tagccagcat cctgctgatg tcaaggcagc
    22981 tcgtattgcg gccctttttc aggcccaatc tttcttagat ccatctgtct tggggactta
    23041 tccacaggag ttggtagaaa tcttgcatga acacggtctt ttacctgatg ctacagagga
    23101 agagttggaa ctcattcgtg ataatacggt ggacttcctt ggtgtgaact actatcaacc
    23161 tttgcgtgtt atggctcctc gatttgctaa gcatccagag agtccactct taccagaaca
    23221 tttttacgag ccttatgtga tgcctggacg taaaatcaat tctcaccgtg gttgggagat
    23281 ttatgagcaa gggatttatg acatcgccca aaatatcaag gaaaattatg gcaatattga
    23341 atggatgttg actgagaatg gtatgggtgt tgaaggggaa gaaaaattcc gtcaagatgg
    23401 aatgattcaa gatgattacc gtattgactt tgtaaaaggt catcttcgtg aacttcaccg
    23461 tgccattgaa gatggtgcca actgtaaggg ctacttgatt tggaccttta ttgactgctg
    23521 gtcatggctc aacagctata aaaatcgcta tggtttggtc gaattagatt tggaaacgca
    23581 agaacgtcgt ctgaagaaat caggccactg gttcaaagaa ttaagcgata ataatggatt
    23641 ttaaaaagga ctctgactga ttatcccaat cggtcagagt tttttgctta caggagctta
    23701 atttgaacta taccaatttt tactcttgac aagtgaaaga aacaagtata tactgttttt
    23761 gctgattcta taaaagatga attagactat accaatttta aggagaaagc acagcttgcc
    23821 tgtgtcgtat atactatgtg tggaattgtt ggtgttgttg gaaacacaaa tgcaactgat
    23881 attttgattc aagggcttga aaagcttgaa taccgtggct atgattctgc gggaattttt
    23941 gtcctagatg gtgctgataa ccatttggtg aaggctgttg gtcgtatcgc agaattgtct
    24001 gccaagacag ctggtgttga gggaacaact ggtatcggac atactcgttg ggcaactcat
    24061 gggaaaccaa cggaagacaa tgctcaccca caccgctctg agacagaacg ttttgtcttg
    24121 gttcacaatg gggtgattga aaactacctt gaaattaaag aagaatacct tgctgggcac
    24181 cacttcaaag ggcaaacaga tacggaaatc gccgtacatt tgattggaaa atttgcggaa
    24241 gaagacggtc tctcagttct tgaagccttt aaaaaagctc ttcatattat ccgtggttca
    24301 tatgcctttg ccttgattga ctctgaaaat ccagatgtca tctatgtagc gaaaaacaaa
    24361 tctccacttt tgattggtct tggggaaggc tacaatatgg tctgctcaga tgctatggct
    24421 atgattcgtg aaaccaacca atacatggaa attcatgacc aagagttggt aatcgtcaag
    24481 gctgatagcg tggaagttca agactatgat ggtaacagtc gtgaacgtgc tagctatact
    24541 gcggaacttg acttgtcaga tatcggtaag ggaacttatc cttactacat gcttaaggaa
    24601 attgatgagc aaccaactgt tatgcgtaaa ctcattcaag cctacacgga tgatgctggt
    24661 caagtagtga ttgatcctgc tatcattaag gctgttcaag acgcagaccg catctacatc
    24721 cttgcagctg gaacatctta ccatgcagga tttgcttcta agaaaatgtt ggaagaattg
    24781 acagatacac cagttgaact tggaatctca tctgagtggg gctacggtat gccacttctc
    24841 agcaagaaac cactcttcat ctttatcagc caatctggtg aaacagcgga tagtcgtcaa
    24901 gttttggtca aggctaatga aatgggaatt ccaagcttaa cagtgacaaa cgttccaggt
    24961 tcaaccctct cacgtgaagc caactatacc atgctccttc acgcaggtcc tgaaattgcc
    25021 gtggcatcaa ctaaagccta tacagcgcaa atcgcagccc ttgccttcct tgcaaaagca
    25081 gtcggagaag caaatggtaa tgctaaagcg caagcctttg acctggttca tgaattgtca
    25141 atcgtagctc agtctatcga atcaactctt tcagagaaag aaaccattga agccaaggtt
    25201 cgtgaacttc ttgaaacaac tcgtaacgcc ttttacatcg gacgtggtca agattactac
    25261 gtagccatgg aagcaagtct caaactcaaa gagatttctt atatccagtg tgaaggtttt
    25321 gcggcaggag aactcaagca cggaaccatt gccttgattg aagaaggaac gcctgtcttg
    25381 tctctcttgt cagatccagt tcttgccaac catactcgtg gaaatatcca agaggtcgca
    25441 gcccgtggtg ccaaagtcct cactatcgca gaagagaatg tagccaaaga taccgacgat
    25501 atcgtcctta cgaccgtaca tccatacctc tcaccaattt caatggtcgt accaacgcaa
    25561 ttagtcgctt actttgcaac cctccaccgt ggcctcgatg tggacaaacc acgtaacctt
    25621 gccaagtcag taacggtaga ataagctaaa aaagtctagt tatctaggcc tttttcttgt
    25681 gagcaaattg gttgcttgta ctcaagattc gtgttatact cttcgaaaat ctcttcaaac
    25741 cacgtcaacg tcgccttgcc gtaggtatgg ttactgactt cgtcagttct atccacaacc
    25801 tcaaaacact gttttgagca gcctgcggct agcttcctag tttgctcttt gattttcatt
    25861 gagtattaga ataatttttc aaattgaagt acagagatag ataaggagaa tcacaatggt
    25921 agaattggga atttcaacat ttggggaaat aacggagctt gaagggactg gacaaactta
    25981 cagtcatgct gaacgcattc gccagttggt ggcagagatt gagctggctg acaaggttgg
    26041 tttggacgta tatgggattg gcgagcacca tcgggcggat tttgcagtat cagccccaga
    26101 gattgtcctg gccgctgggg cagtcaatac caagaaaatc cgtttgacca gtgcagtcag
    26161 cattctgtca agcatggatc cgattcgttt gttccaacag tatgccacta tcgatgcttt
    26221 gtcaaatgga cgatcggaga ttatggctgg aaggggctct ttcacggaat ctttccctct
    26281 gtttggttat gacttgaaag actacgactc tctttttgat gagaaattag acttgcttca
    26341 gttagtcaat gaaaagacca agttagactg gcaaggtcga ttgactcaaa cgattgctgg
    26401 taaagaagtt tatcctcgtc cagttcagga caaattgccc ttgtggatag ctacaggtgg
    26461 tcatgtcgaa tcaacagtga agattgctca ggctggtcta ccgattgtat atgctattat
    26521 tggtggtaat ccacgttatt ttaaaaagtt gattcaggct tatcgtgaga ttggaagcga
    26581 agcgggccat gctgacaaag acttgaaagt gggagcccat tcttgggggt ggattgcgga
    26641 agatggtgag caggcggtga aagattattt ccatccgact aagcaagtgg tggatgctat
    26701 ttccaaagac cgtccgcact ggcaggaatt gcgttatgag caatatttgg agcaggtagg
    26761 gccaaatggc gccatgtttg ttggcaatcc agatcaggtg gccgaaaaat tgattcgcat
    26821 gatagaggat ttaggattgg accgcttcat gcttcatcta ccgcttggtt ctatgcctca
    26881 tgaccaggtt ctgagagcta ttgaactctt cggaacacaa gttgcaccca aagtacgagc
    26941 ttattttgct atgaaagagg cttaataaaa aatcctaatc aagtttatta ggacaacaaa
    27001 tattgtacaa aaattaatcc cccgagctat aatgcttggg ggatttttct ataggagggc
    27061 tagtttagtt ctctttttta ttttttagta agaaaccgag accaaggagc gcaaggaggc
    27121 tgattcctgc aaataggagt ttgttttcgt ttttgattcc tgtatttgga agttcagctt
    27181 gtttatctgg ggttgcaggt atattttcct tgctagagtt ttctaccgat tcgtttcgaa
    27241 ccgcttcttt tacagatgat gcttgtgctt cttgtgcttc ttgtgctggt tgttcagctt
    27301 gtgaatcagc tgtagcttgg ctaggtttat tttccgcatc agctactttg gcatctggtt
    27361 tagtagaatc aggtctagct tctggagctg ggtcttgatg tgcagggtga gaagcttcat
    27421 tttgatgttc aggcttggaa ggggttgagt ctggtttctc ttctgcagtt gactcatggc
    27481 tagttccatt ttgagagact cgaagaacag tagctgtaag ggcattcaat ttcaagcctt
    27541 tttcagtcca ttcaagtcct ttcgggttgg caattccgac tgatcctgct tggttttcat
    27601 ctgccaaaac ttccgcattt cttagatgtg caaaggcagt tcccaaatta aattcgcgag
    27661 ctttttcatc cgcattgaca aagactgcgt agatatcgcc gtttggagca gtgatttggt
    27721 agccaatcac tacatcctct ttttccacac cattttggcc tgggacagtg atgaggtgga
    27781 cacggtcttt gatatcttga agactcttaa gtcggaaggc atctgtagat tgacgaaggg
    27841 caatcaaacc tttcatatag tcacggctct tgacattttc aggataagct ttaccatctg
    27901 tagccttagt ccagtcaaac ttgttgactg catcgctaga atcgtaagaa tcatggatga
    27961 agtaaggata gtcaaatggg ttgccgtcct tatcacgcaa caagtgagat ttgtttggaa
    28021 ccttatcctc tgctactgga gtcttgtagg ctgggtcacg gaattgttta gtacgtccat
    28081 attcctgacc ggagtggata aatggagttc cttgagctgt caagaccatg agatttccaa
    28141 gtcgtaaacg acggtggatt tcagcatagt tctcagcctt gcttgggtct tttttgatag
    28201 actgggcaat gatgtcaaag agggtcaagt tatcatgggc tgcgatgtat tggatgacat
    28261 ctccagggct gtcagcttca aagttagttg gttgagcaat gagattttta aagatggtgt
    28321 tgacatcacg cttgccacct gtgataaagg caggttgacc ttcgtttgga taaccagatt
    28381 tgaggttgtt acggatgtca tctgaaaaga cagcgacagt atcggtatgt ttcatccaat
    28441 cttggtcagc agctttagta ggcatgtttt catcaccggc ataggttctc caaccttcac
    28501 caagcatgat gaggtttgga ttgagggcgc gtgcagcctt gtaagcttct tcgatagaag
    28561 cggcgtcatg gtctcccatc atatcgaagc ggaagccatc cactttgtag gtatcaacta
    28621 ggtatttgat agagtcaact aggagccgtt tggtcatatg gtgggttgtc cccaagcgtc
    28681 caccaccaaa gctagttcga ggtgtgccat cggcatccat aaagtggtag tagtttggct
    28741 ctaggtcttc aaagatatcg actttggctg tgtggttata aacgacatct aggatagctc
    28801 ccataccacg tttgtggatt tcgttgatga ggtttttaaa ttctgcgatt cgtttttctg
    28861 gattcttagg atcgcttgag tacataccag tcaaggagaa gtagttttga gggtcatatc
    28921 cccagttgta gttgctgttg cttgaagcgt agtcagacaa gcgttcatgg tttttcaatt
    28981 cattgacaaa gtagtaagac aagactggaa ggagctggat atgggttaca cccaagtctt
    29041 tgagatagtc tagtttttca atgaaggctt caaaagtccc aaatggtttg gtcaagtctt
    29101 ttgcaatggc aggatctgaa gtgaagtcac gcacatgagc ttcgtagata acggcgtctt
    29161 cacgagtctt gaaattgtga atcttaccat aagtcaagtc ttgaggtccg agtttagctg
    29221 gatctacaaa ggcggcttta gccactttat ggacatcgtc aattttggca tcgtcgctat
    29281 tccaagcagc aagagattta gcgtaaggat cgagtgcaag aacagtttta ccttgacgct
    29341 cgatttggta ttgataatag tagccagtga aatctgtgat tccgagtttg tttgtgctgt
    29401 ctagagtttg tttccaagtt cctctttccc ctttttcgag agcgacagtt ccaactactt
    29461 tgtcagggtc attcttgtcg tagacaacaa cagaaacctt atcagcactt ggtgaccaaa
    29521 gggtcaaatc aacttgtttt ccttcttctt ttaggtcagc tcccagtttg ccatcatagc
    29581 tgtatgtctc atctttcagg cgccagcttg ttttggtagt gaattggtcg gaattgtagc
    29641 taacagtata aggatgtttt gtgtcagaga aatctccgct gtaggtcact ttcttaccag
    29701 cttcatcgat tgcaacatcg gtaatagtta ccttgtttcc taggtgatta gtgatgttgg
    29761 agtgtttgag gatatcttct tttttagcac cgacaagtgt tgaaaagcta ctttcaatgc
    29821 tagaagtgcc tacgtgttgg gctcctgtca tacggatatc atggacatag tatggatttg
    29881 tgtaaatcga ttcatcatcg tcttttagga aaatttggct atgatttttc aaatctgtga
    29941 acttataatt ttctttacgg attttcacgt cgactccttg tttgctctca tctagtaata
    30001 aaaatccaaa ttctcttgcg gcttcattaa gaggaatgtc gatatagcgg ccatatttgc
    30061 ctgtagccgt aaagtctgtt ccgtcaggcc attgagcgct acttggattt tttacatctc
    30121 cccagtacca gagagatttc ttgtcatagt tgccatctgt gcggtagtag ttgacgcgaa
    30181 cagttcctgc aggctgtggc tcgtaagaga aaaccttgta atcttggtct aaccaagcct
    30241 cgttcatttt tggaactagt ttttctacag atttatcgcc ggttagattt tttccagctg
    30301 tattgttgat gaggaagcta attttcttgg cttgttctcc ctttaatttg acatctaggt
    30361 aatagccgta gtcatctttc ttggcatcct tgaaggacaa agctccgttt ggccagtttt
    30421 cagatggttt ttcaacatcg tcccaagtcc atagtccttg agcatccttg ttttcttcag
    30481 gaagtttttt gacatggata cggaagtagt tatcttcgat gggctcttct gccttagttt
    30541 cagttgttac tggactagta gaagtagttg gctctgttgc aggtttttct tctgttttct
    30601 ctagggaagc gtttgcattt ctaggtgaag aaatatcact ttcgttctta ccagagccag
    30661 ctgctgtatc agtaagaggt tgggcaaggg tggttgtatt tctgttgttg ggttcgttag
    30721 tggttggtgt actttcgtcg gatgagatag ttggtgtagc catggcaagc aagacaaggc
    30781 ttgcgccgat aaggacagaa ccagttccat ttttgaggga acggatgctg tagaccattt
    30841 ttttctcagt gtgagatggt gtttttctca taatgattct ccaatcaata aatttctata
    30901 tcagtatagc atgtagtaaa acaatatgca agcgttttct ttgatttgtg aaaaaaattc
    30961 ttacttttga gaagttttct gtactatttt atatatcagt ataaatgacg gagataaaaa
    31021 tgtcacataa gccaagccgt attattagga agatgatgtg ttcccagcta tttttattca
    31081 gaaattgatc tctaacatta ccaataaaaa agaaaaatat cttgacaagc aagggaaaat
    31141 tttgttacaa taataaacgg tactttttac ttttggtctc tcaagagtgt acagggacgt
    31201 gctgacaaat gttgcaaaag tacacacaga tgatatctgt caccaagtgt atcatcacca
    31261 aaaataaaaa aacacaggag aatgtagatg cctacaatta accaattggt tcgcaaaccg
    31321 cgtaaatcaa aagtagaaaa atctaaatca ccagctttga acgttggtta caatagtcat
    31381 aaaaaagttc aaacaaacgt ttcttcacca caaaaacgtg gtgttgcaac tcgtgttgga
    31441 acaatgacac ctaaaaaacc taactcagcc cttcgtaaat tcgctcgtgt acgtttgagc
    31501 aaccttatcg aagttactgc ctacatccca ggtatcggac acaacttgca agagcacagc
    31561 gtggtgcttc ttcgcggtgg acgtgtaaaa gaccttccag gggtacgtta ccatatcgtc
    31621 cgtggtgcac ttgatactgc aggtgttaac gatcgtaaac aaggccgttc taaatacggt
    31681 actaaacgtc caaaagcata aggaaagggg ataaagagaa atgagtcgta aaaatagagc
    31741 tccaaaacgt gacgtattgc cagatccgct atacaattca caactagtta ctcgtcttat
    31801 caaccgcgtt atgcttgatg gtaaacgtgg tactgctgct tcaatcgttt acggtgcttt
    31861 tgagcaaatc aaagaagcta ctggcaacga tgcacttgaa gtatttgaaa cagctatgga
    31921 aaacatcatg cctgtacttg aagtacgtgc acgtcgtgtt ggtggttcta actaccaagt
    31981 cccagttgaa gttcgtccag aacgtcgtac aacacttgga cttcgttggt tggtaacaat
    32041 cgctcgtctt cgtggtgaac acacaatgca agaccgtctt gcaaaagaaa tcttggatgc
    32101 tgctaacaac actggtgcag cagttaagaa acgtgaagat actcaccgta tggctgaagc
    32161 taaccgtgca ttcgcacact tccgttggta agataggatg cgaaagcgtt aagaaagtcc
    32221 cagagaaaat agggaatcga agcaggttgc ggttgcaacc aatgagattc atctttttct
    32281 ccagactttt agcttgagct caactaaatc atgatgctag gaacggtaag gatgcaaggt
    32341 gaaaatagga aactgacgca gtattcgacg aatataagga gttttatctt tttcacgcag
    32401 catcccgttc cagctcacat cggctaacta actttagccc gggttcaaat tagctaaatc
    32461 gattagtatt agctataact cagcttacca tctcgtaagt tgaaaccaac aatagcatga
    32521 aaacattgag aacgggtagg tcctgcctat ccgtttttat taaaatcgtg ttataataga
    32581 atagaaatca aaaataaata ggagaaacaa acctcatggc acgcgaattt tcacttgaaa
    32641 aaactcgtaa tatcggtatc atggctcacg tcgatgccgg taaaacaaca actactgagc
    32701 gtattcttta ctacactggt aaaatccaca aaatcggtga aactcacgaa ggtgcgtcac
    32761 aaatggactg gatggagcaa gagcaagaac gtggtatcac gatcacatct gctgcgacaa
    32821 cagctcaatg gaacaaccac cgcgtaaaca tcatcgacac accaggacac gtggacttca
    32881 caatcgaagt acaacgttct cttcgtgtat tggatggtgc ggttaccgtt cttgactcac
    32941 aatcaggtgt tgagcctcaa actgaaacag tttggcgtca agcaactgag tacggagttc
    33001 cacgtatcgt atttgccaac aaaatggaca aaatcggtgc tgacttcctt tactctgtaa
    33061 gcacacttca cgatcgtctt caagcaaatg cacacccaat ccaattgcca atcggttctg
    33121 aagatgactt ccgtggtatc attgacttga tcaagatgaa agctgaaatc tatactaacg
    33181 accttggtac ggatatcctt gaagaagaca tcccagctga ataccttgac caagctcaag
    33241 aataccgtga aaaattgatt gaagcagttg ctgaaactga cgaagaattg atgatgaaat
    33301 acctcgaagg tgaagaaatc actaacgaag aattgaaagc tggtatccgt aaagcgacta
    33361 tcaacgttga attcttccca gtattgtgtg gttcagcctt caaaaacaaa ggtgttcaat
    33421 tgatgcttga tgcggttatc gactaccttc caagcccact tgacatccca gcaatcaaag
    33481 gtattaaccc agatacagac gctgaagaaa ttcgtccagc atctgacgaa gagccatttg
    33541 cagctcttgc cttcaagatc atgactgacc cattcgtagg tcgtttgaca ttcttccgtg
    33601 tttactcagg tgttcttcaa tcaggttcat acgtattgaa tacttctaaa ggtaaacgtg
    33661 aacgtatcgg acgtatcctt caaatgcacg ctaacagccg tcaagaaatc gacactgttt
    33721 actcaggtga tatcgctgct gccgttggtt tgaaagatac tacaactggt gactcattga
    33781 cagatgaaaa agctaaaatc atccttgagt caatcaacgt tccagaacca gttatccaat
    33841 tgatggttga gccaaaatct aaagctgacc aagacaagat gggtatcgcc cttcaaaaat
    33901 tggctgaaga agatccaaca ttccgcgttg aaacaaacgt tgaaactggt gaaacagtta
    33961 tctcaggtat gggtgaactt caccttgacg tccttgttga tcgtatgcgt cgtgagttca
    34021 aagttgaagc gaacgtaggt gctcctcaag tatcttaccg tgaaacattc cgcgcttcta
    34081 ctcaagcacg tggattcttc aaacgtcagt ctggtggtaa aggtcaattc ggtgatgtat
    34141 ggattgaatt tactccaaac gaagaaggta aaggattcga attcgaaaac gcaatcgtcg
    34201 gtggtgtggt tcctcgtgaa tttatcccag cggttgaaaa aggtttggta gaatctatgg
    34261 ctaacggtgt tcttgcaggt tacccaatgg ttgacgttaa agctaagctt tatgatggtt
    34321 catatcacga tgtcgactca tctgaaactg ccttcaagat tgcggcttca ctttccctta
    34381 aagaagctgc taaatcagca caaccagcta tccttgaacc aatgatgctt gtaacaatca
    34441 ctgttccaga agaaaacctt ggtgatgtta tgggtcacgt aactgctcgt cgtggacgtg
    34501 tagatggtat ggaagcacac ggtaacagcc aaatcgttcg tgcttacgtt ccacttgctg
    34561 aaatgttcgg ttacgcaaca gttcttcgtt ctgcatctca aggacgtggt acattcatga
    34621 tggtatttga ccactacgaa gatgtaccta agtcagtaca agaagaaatt attaagaaaa
    34681 ataaaggtga agactaatcc gtcctcactc tagaaggaag tcacttagtg gcttcctttt
    34741 gtctttagaa aatacctcta aatatggtaa aatagtagaa gaataatgtg aggaaaatga
    34801 atgtcaaata gttttgaaat tttgatgaat caattgggga tgcctgctga aatgagacag
    34861 gctcctgctt tagcacaggc caatattgag cgagttgtgg ttcataaaat tagtaaggta
    34921 tgggagtttc atttcgtatt ttctaatatt ttaccgattg aaatcttttt agaattaaag
    34981 aaaggtttga gcgaagaatt ttctaagaca ggcaataaag ctgtttttga aattaaggct
    35041 cggtctcaag aattttcaaa tcagctcttg cagtcctact atagggaggc tttctctgaa
    35101 ggtccatgtg ctagtcaagg ttttaagtcc ctttatcaaa atttgcaagt tcgtgctgag
    35161 ggtaatcagc tatttattga aggatctgaa gcgattgata aggaacattt taagaagaat
    35221 catcttccta atttagccaa acaacttgaa aagtttggtt ttccaacttt taactgtcaa
    35281 gtcgagaaga atgatgtcct gacccaagag caggaagagg cctttcatgc tgaaaatgag
    35341 cagattgttc aaactgccaa tgaggaagcg ctccgtgcta tggaacaact ggagcagatg
    35401 gcacctcctc cagcggaaga gaaaccagtc tttgattttc aagcgaaaaa agctgcagct
    35461 aaacccaagc tggataaggc ggagattact cctatgatcg aagtgacgac agaggaaaat
    35521 cgtctggtat ttgaaggggt tgtttttgat gtggagcaaa aagtgactag aacaggtcgt
    35581 gttttaatca actttaaaat gacggactat acttcaagtt tttctatgca aaagtgggtt
    35641 aaaaacgagg aagaggccca gaagtttgac ctcatcaaga agaattcttg gctccgagtt
    35701 cgagggaatg tggagatgaa taacttcaca cgcgatttga ctatgaacgt acaggatctg
    35761 caggaagttg ttcactatga gcggaaggat ttgatgccag aaggtgagcg tcgggttgag
    35821 tttcatgctc atactaacat gtcgactatg gatgctttgc cagaggtcga agagattgtt
    35881 gcaacagctg ctaagtgggg acacaaggcg gttgctatca cagaccatgg gaatgtccag
    35941 tcctttccac atggctataa ggcggctaag aaagcgggaa tccagctgat ctatgggatg
    36001 gaagccaata tcgtggagga ccgtgtccct atcgtctata acgaagtgga gatggactta
    36061 tcagaagcaa cctacgtggt ctttgacgtg gaaacgacgg gactttcagc tatctataat
    36121 gacttgattc aggttgcggc ctctaagatg tacaagggga atgttattgc tgaatttgat
    36181 gaatttatca atcctgggca tcccttgtca gcttttacta cagagttaac tggaattaca
    36241 gatgatcatg tcaaaaatgc caaaccacta gaacaagttt tgcaagaatt ccaagaattt
    36301 tgcaaggata cggtcctagt tgcccacaat gctacctttg acgttggctt tatgaatgct
    36361 aattatgagc gtcatgatct tccaaagatt agtcagccag ttattgatac gctggagttt
    36421 gctagaaacc tctatcctga gtataaacgc catggtttgg ggcctttgac caagcgtttt
    36481 ggtgtggcct tggaacatca ccacatggcc aactacgatg cggaagcgac tggtcgtctg
    36541 cttttcatct ttatcaaaga ggtagcagaa aaacatggtg tgaccgattt agctagactc
    36601 aacattgatc taatcagtcc agattcttac aaaaaagctc ggatcaagca tgcgaccatc
    36661 tatgtcaaga atcaggtagg tctaaaaaat atctttaagc tggtttcctt gtctaatacc
    36721 aagtattttg aaggagtgcc acggattccg agaacggttc tagatgccca tcgagagggc
    36781 ttgattttag gttcagcctg ttcagagggt gaagtttttg acgtggtcgt ttctcaaggt
    36841 gtggatgcgg cggttgaggt ggccaagtat tatgacttta tcgaggtcat gccaccggct
    36901 atctatgcgc ccttgattgc caaagagcag gtcaaggata tggaggaact ccagaccatt
    36961 atcaagagtt tgatagaggt tggagatcgc cttggcaagc ctgttctggc tacgggaaat
    37021 gttcactata tcgaaccgga agaagagatt tatcgtgaaa ttatcgtccg tagtttggga
    37081 cagggtgcga tgattaaccg aactatcggt catggtgaac atgcccaacc agcgccactt
    37141 ccaaaggctc attttcgaac gactaatgag atgttggatg aatttgcctt tttgggagag
    37201 gaactggctc gtaaactggt tattgaaaac accaatgcct tggcagaaat atttgaaccc
    37261 gttgaagtcg ttaagggtga cttgtatacg cctttcatcg acaaggctga agaaacagtt
    37321 gctgagttga cctataagaa agcttttgag atttatggaa atccgctgcc agatattgtt
    37381 gatttgcgga ttgaaaaaga attaacatcc atactgggga atggatttgc tgtgatttat
    37441 ctggcatcgc agatgctggt gcaacgttct aatgaacggg gttatttggt tggttctcgt
    37501 gggtctgtcg gatctagttt cgttgcgacc atgattggga ttacggaggt caatcctctc
    37561 tctcctcact atgtctgtgg tcagtgtcag tacagtgagt ttatcacaga tggttcgtac
    37621 ggttcaggat ttgatatgcc ccataaggac tgtccaaact gtggtcacaa actcagtaaa
    37681 aacggacagg atattccgtt tgagaccttc cttggttttg atggggataa ggttcctgat
    37741 attgacttga acttctcggg agaagatcag cctagcgccc acttggatgt gcgtgatatc
    37801 tttggtgaag aatatgcctt ccgtgcggga acggttggta cggtagctgc caagactgcc
    37861 tatggatttg tcaagggtta cgagcgagat tatggcaagt tttatcgtga tgcagaagta
    37921 gaacgcctcg ctcaaggagc ggcgggtgtc aagcggacaa caggccaaca cccgggggga
    37981 atcgttgtta ttccgaacta catggatgtc tacgatttta cgcctgtcca gtatccagca
    38041 gatgatgtca cggctgaatg gcagaccact cactttaact tccacgatat cgatgagaac
    38101 gtcctcaaac tcgatgtact gggacatgat gatccgacca tgattcgaaa acttcaggat
    38161 ttgtctggta ttgaccctaa taaaattcct atggatgacg aaggcgtgat ggcactcttt
    38221 tctgggactg atgtactagg ggtaacacct gaacaaattg gaacgcctac gggtatgttg
    38281 gggattccag agtttggaac aaatttcgta cgtggaatgg tagacgaaac ccatccgaca
    38341 acctttgcgg aattacttca gctgtctggt ctgtcccacg gtactgacgt ttggttgggg
    38401 aatgctcagg atctgattaa gcaaggaata gcggacctat cgactgttat cggttgtcgg
    38461 gacgacatca tggtttacct catgcatgcg ggtctggaac ctaagatggc ctttaccatt
    38521 atggaacggg tacgtaaggg tttgtggcta aagatttcag aagaggagag aaatggctat
    38581 atcgaagcca tgaaggctaa taaggtgcca gagtggtata tcgaatcctg tgggaaaatt
    38641 aagtacatgt tccctaaggc ccatgcggca gcctacgtta tgatggcctt gcgtgtagct
    38701 tacttcaagg ttcaccatcc tatttattac tactgtgctt acttctccat tcgtgctaag
    38761 gcttttgata tcaagaccat gggtgcgggc ttggaggtca tcaagcgcag aatggaagaa
    38821 atctctgaaa aacggaagaa caatgaagcc tctaatgtgg aaatcgatct ctatacaact
    38881 cttgagattg tcaatgagat gtgggaacga ggtttcaagt ttggtaaatt agatctctac
    38941 cgtagtcagg cgacagagtt cctcatcgac ggggataccc ttatcccacc atttgtagca
    39001 atggatggtc tgggagagaa cgttgccaag caactggtgc gggcgcgtga agagggagaa
    39061 ttcctctcta aaacagaact acgcaagcgt ggtggactct catcaacctt ggttgaaaag
    39121 atggatgaga tgggtattct tggaaatatg ccagaggata accagttgag tttgtttgat
    39181 gagttgtttt aaaaaattgc ttaataatct attaaaagag gctaacgtat atccaataga
    39241 tttacattag ctttcttttt tgttaaaata gtctatggaa agagggtgag agtatgtcaa
    39301 agatgagtat aagcatccgt ctggatagtg aggttaagga gcaggcccaa caggtgttta
    39361 gtaatctggg aatggatatg acaacagcta ttaatatttt ccttcgtcag gcaattcaat
    39421 atcagggatt accttttgat gttagactag acgaaaatcg gaagttgctc caagcgttaa
    39481 cggatttaga ccaaaatcgt aatatgagcc agtcttttga atcagtctca gatttgatgg
    39541 aggacttacg tgcttaagat tcgttatcat aaacagttta aaaaagattt taagttggct
    39601 atgaagcgtg gtttgaaggc agaattatta gaagaagttt tgaattttct ggttcaagaa
    39661 aaagaacatc ctgccagata tcgtgatcat tcattgacgg catccaagca ttttcaagga
    39721 gttcgtgaat gccataccca gccagattgg cttttggttt ataaagtaga caagtcggaa
    39781 ttgattttaa atttgctgag gacaggcagt cacagtgatt tattttaatc tattttaagg
    39841 gggttctcat gaaactaaga atatttgcgg aagataagcc ggctaagaag gtatttgaat
    39901 atcaattaga acttgctgat cgtacaattc ttctatcgac agcactcttg tcaggtgcta
    39961 ttgctttagc aggaatcttt tctgctttga aagaaaaata aaaatagaaa agagaaaaca
    40021 gaatggtttt accaaatttt aaagaaaatc tagaaaaata tgcgaaattg ttggttgcga
    40081 acggaattaa cgtgcaacct ggtcacactt tggctctctc tattgatgtg gagcaacgtg
    40141 aattggcaca tctaatcgtg aaagaagctt atgccttggg tgcgcatgag gtcatcgttc
    40201 agtggacaga tgatgtgatt aaccgtgaga aattcctcca tgccccgatg gagcgtttgg
    40261 acaatgtgcc agaatacaag attgctgaga tgaactatct tttggagaac aaggctagcc
    40321 gtcttggggt tcgttcatct gatccaggtg ccttgaacgg agtggacgct gacaagcttt
    40381 cagcttctgc taaagctatg ggacttgcca tgaagcctat gcgtatcgca actcaatcta
    40441 acaaggttag ctggactgta gcagccgctg ctggacttga gtgggctaag aaagtcttcc
    40501 caaatgctgc gagcgacgaa gaagcagttg atttcctttg ggatcaaatc ttcaaaactt
    40561 gtcgtgtcta cgaagcagat cctgttaagg cttgggagga acatgcagcc attctcaaga
    40621 gcaaggccga tatgcttaat aaggagcaat tttcagccct tcactacaca gcgccaggaa
    40681 cagatttaac acttggtttg ccaaagaacc acgtttggga atcagctggt gctgtcaatg
    40741 cacagggcga agaattcttg ccaaatatgc cgacagaaga ggtcttcaca gcgcctgact
    40801 tccgtcgtgc agatggttat gtcacttcta caaaaccgct tagctacaac ggaaatatca
    40861 ttgaaggcat taaggtgacc tttaaggatg gacaaatcgt agatatcact gctgagaagg
    40921 gtgatcaggt tatgaaagac cttgtctttg aaaatgcggg tgcgcgtgcc ttgggtgaat
    40981 gtgccttggt accagatcca agtccaattt ctcagtcagg cattaccttt tttaacaccc
    41041 ttttcgatga aaatgcgtca aaccacttgg ctatcggtgc agcctatgcg actagcgttg
    41101 ttgatggagc ggagatgagc gaagaggagc ttgaagctgc agggcttaac cgttcagatg
    41161 ttcacgtaga ctttatgatt ggttctaacc aaatggatat cgatggtatt cgtgaggatg
    41221 gaacgcgggt acctcttttc cgtaatggga attgggcaaa ttaaggagat aatatgttag
    41281 gaagtatgtt cgttggtctc ctagtgggat ttttagcagg tgctatgacc aatcgtggag
    41341 agcgaatggg atgttttgga aaaatgtttc tcggttggat cggagccttt ctaggtcact
    41401 tgctctttgg aacttggggg ccagttttat caggaacagc tattatccca gcgattttag
    41461 gagccatgat tgttttagct attttttgga gacgaggaag ttaatttcct aaatctgata
    41521 ctcaatgaaa atcaaagagc aaactaggaa actagccgca ggttgctcaa agcactgctt
    41581 tgaggttgca gatagaactg acgaagtcag ctaaaaacac tgttttgagg ttgcagatag
    41641 aactgacgaa gtcagtaaca tatatacggc aaggcgacgt tgacgcggtt tgaagagatt
    41701 tttgaagagt atgaaacgaa aaggaggttg gtcattgtac tagcctcctt ttgatatgat
    41761 ataatagttc tatgagatta gataaatttt tagttgcctg tgcggtggga agtcggactg
    41821 aggtcaaaaa cttgctcaag gctgggcgcg tgactgtaaa tggtaaaaaa gaaaaatcag
    41881 ctaaattgca gattgatgaa aaaatagatg agattcgctt tgatgggcaa gtgttggagt
    41941 atgaagagtt tgtctactac atgatgaaca agcccaaagg agttatctca gcgactgagg
    42001 atcccaagca cagaaccgtt ctggacttgt tggatgactt ggcgcggagt aaggaagttt
    42061 tcccagtagg acgcttggat attgacacgc atggtctttt gctcttgacc aatgatggtc
    42121 agctggctca tgttcttctt tcgcccaagc gtcatgtgga caagacttat ctggcacaag
    42181 tcaagggaat catgacccaa gaagatgtgg agacatttgc tgagggtatt cctctcaaag
    42241 actttacctg tcaacccgct atactggagc ttgtatccat agatacagaa aagaatcaaa
    42301 gccaaatccg tgtgaccatt gcagaaggga agtttcatca gatcaagcgt atggtgggct
    42361 attgtggcaa ggaagtggtg gacttgcaac gattgactat gggaacttta gtattagatg
    42421 agaacctgga acgaggggaa tggcgtcgct tgaccaagga agaattagaa attctccgcg
    42481 ctaatattat ttaatttagt ttaatactca atgaaaatca aagagcaaac taggaaacta
    42541 gccgcaggct gtacttgagt acggcaaggc gacgttgacg tggtttgaat ttgattttcg
    42601 aagagtataa attcgaaaaa ggtgagggac aatgtcctcg ccttttatgt tttttagttg
    42661 cttcctttgt gaaaagagtt ataatagact gtagaataaa aggaggaatc tatgaacgcg
    42721 attcaagaat catttactga taaactattt gccaactatg aagcaaatgt aaaataccaa
    42781 gcgattgaaa atgctgccag ccacaacgga atttttgcag ctctggaacg tcgccaaagc
    42841 catgtagaca acacacctgt tttctcattg gatttaacca aggacaaggt cactaaccag
    42901 aaagcgtctg gtcgttgctg gatgtttgcg gctctcaaca ccttccgcca caaactcatc
    42961 tcgcaataca aattggagaa ctttgagttg tcacaagccc acactttctt ctgggataag
    43021 tatgagaaat caaactggtt cttggagcaa gtcattgcga cttcagacca agaattgact
    43081 agccgcaagg ttagcttctt actccaaaca cctcaacaag atggcggtca atgggatatg
    43141 gtcgtttccc tctttgaaaa atacggtgtc gtgcctaagt cagtttatcc tgagtctgtt
    43201 tcatctagca gcagtcgtga gctaaatgcg atccttaata aattgcttcg tcaagatgct
    43261 caaatcttgc gtgatttgct tgtttctggt gcagatcaag tgactgttca agctaagaaa
    43321 gaagacctct tgcaagaaat ctttaacttt cttgctatgt cattaggact tccaccacgc
    43381 aagtttgact ttgcttatcg cgataaagat aacaactaca aaagtgaaaa aggaatcaca
    43441 ccacaagagt tctacaagaa atatgtcaat cttcctttag aagactacgt ttctgttatc
    43501 aatgctccaa ctgctgataa accttacgga aaatcttaca cagttgagat gttggggaat
    43561 gtggttggta gccgtgcagt tcgttacatc aacgttccaa tggagcgctt gaaagaattg
    43621 gcgattgccc aaatgcaagc aggtgagact gtttggtttg gttctgatgt cggccagctc
    43681 agtaaccgta aggctggaat ccttgcgaca gatgtttatg actttgaatc aagcatggac
    43741 attaaactta ctcaagacaa ggctggacgt ttggactata gcgaaagctt gatgacccac
    43801 gccatggtct tgacaggtgt tgacttggac gaaaatggta aatcaaccaa gtggaaggtt
    43861 gaaaactcat ggggagacaa ggtcggtaca gatggttact ttgttgcctc agacgcttgg
    43921 atggacgaat acacatacca aatcgttgtt cgtaaggaat tgctgacagc agaagaacaa
    43981 gctgcctatg gagcagaacc aattgtactt gcaccatggg atccaatggg agccttggct
    44041 aaataaaagc atagaaaaaa ggaatcagat tttagaacct ggttcctttt tagttgcttg
    44101 attacatgat gtgaagaaca tgtgccacaa tacccactgc gaagagggca aggataatag
    44161 tgattggaga tacttttttc ttaagtaagt acatgcaaag taaagtaagg agtagtcctg
    44221 ataatccagg aatcaacata tccaagtttt gttggaaagt agtaactttt tcaggagttt
    44281 gagacaatcc ttgtcctact tgtgcgaatg cttcttggat acctttagac ccttctggca
    44341 atttatccca atggatataa gccttttcat ctagttgaac tttagaaaca tcgaaagcaa
    44401 atttaatatt tacccagcgt tgaacaagga cagcaagaat gaacatccca aggatagaag
    44461 ctcctttagt gatatcttga aggataccac cagacatatc tttagtgatt tctgatccag
    44521 ccttgtatcc aatctcttga acataccaca agaatgacat acgaatcaag ttccatgcaa
    44581 caaagaagag gagtggcccc aagatattgc cagtaagggc aagtgaagca ccgagagatc
    44641 caaggattgg gcgtactgta aaccagaata ctgggtcacc gataccagca agaggtccca
    44701 tcataccgat tttaacccct tggatagcag cgtcatcgat ttccacaccg ttagcacgtt
    44761 cttcttcaag cgcaagagta acccccatga ctggagcagc tacgtatgga tgagtgttga
    44821 agaactcaag gtgacgctca agagcagcga tttgatcttc ttttttagta tagagttttt
    44881 tgatagctgg aatgagtgta taagcccagc ccaagttttg catccgttca aagttccaag
    44941 acccttgtaa gaaggttgaa cgccaccaaa cttttttacg atctgattta gttaattgaa
    45001 gtttttcagt catgatgttt tcagtccttt cttatcttag tagtcttcta ggatatcgcc
    45061 gattgggtcg ttagaagttg cggctcctcc gccaccattt ccaccagttt tagaaaggtg
    45121 aaggtagata agagcgatag caacaccgat agcaccgaat ccgattagag taatatctga
    45181 cacagcagcg agaacgaaac caagagcgaa gaatggccat acttcacgag ttgccatcat
    45241 gttgataacc atggcgtaac caacggcaac gaccatacca ccaccgatag ccataccatc
    45301 tttgagccag tctggcatgg cactaaggat actttgtaca gtttcagttg gtaccataag
    45361 gagaagagct gcaggaagcg cgatacgaag tccttggaag agtagcgcaa tgaaatgcgc
    45421 acgctccaca gcgccgaagt cacctttttt agcggcagca tctgcagtat gaaccaaacc
    45481 aactgaaatt gtacgaacaa tcattgtcaa gaaaagtcca gctacggcaa gagggatagc
    45541 aaccgcttgg gcaacaccga taccagtctt ggtaaagtca ccaccaagaa ccatgataat
    45601 ggcagcagcg acagaagcaa gtgcagcatc aggagcgata gcagcaccga tatttgacca
    45661 accaagggca atcatttgaa gcgatccacc gaggataatc cctgcttcca agtgacctgt
    45721 tacaagccca ataagggtac aggctacaag tggttggtga aattggaact ggtcgaggat
    45781 gccttcaaga cctgcaaaga aggctacaac gactactaaa accatagaaa taatagacat
    45841 gtttaaaatc ctttcataaa taatggctta tttgacattg gctttgttaa tcaagtcaaa
    45901 caaatctttt ttagaatcat ttggtacttt acggacatca aattcaacac ccaagtcacg
    45961 cattttttca aatgtagcaa catcttcttt gtccatagac aaaacggtat tgaccaatgt
    46021 tttacctgtt gagtgagcca tagaaccaac gttaagagtc ttgattggca cgccgccttc
    46081 gatggcacga agggcatctt gaggtgtttc aaacaagata agggcatgtg tttctccaaa
    46141 acgtgggtct tttgaaatct caatcagttt ttgaattgga accacgttag ccttgacatt
    46201 acctggagct gcttgtttaa tcaattcttt acgaaggtcg tctttagcca cgttatctga
    46261 agcaacgatg atacgatttg cttttgaatc tggagtccaa gcagttgcaa cctgaccgtg
    46321 aagtagacgt gtgtcaagac gggcaagatt gattttcaat ttaccgtctc cgataacagt
    46381 tccttctggg atagcagttt gggcaactgg agcagctgca gcgcttgcaa cttcttcaac
    46441 tggatttagc tcttctggaa gagctttgat gccatctttg gcttctttaa tgatattagc
    46501 agcgactttt tctacacctg cagcagcgtc catgaggcgc tctgtgtagg cttgaatcaa
    46561 catcggtaag ttaagtcctg tgatgatggc aaacttacgc tcaggatttt ctcccatcac
    46621 gcgactagct tggttaaatg gagaaccact ccaaaggtca gccaaaacta gaacctcatc
    46681 ttctgcgtca aatgcagcaa cagcgttatt aaacttagcg tatagatcat caggaccttc
    46741 atttggcata aaggtcacaa cttgaacctt ttcttgttca ccaaagatca tagatcctga
    46801 ctgatgaata ccagcagcaa attcgccgtg gctcgcaata atgattccga tactcattat
    46861 tgtcattcct ccttttttgt tttagttttc atttaagaaa actttaagac tgtttaagta
    46921 taaaccgttt tcataaaaaa agcaactatt tatcataaaa aattaaaaaa tttttatttt
    46981 tgtatgttga tatgttgagt ttttgaggag taatcttgaa ttcttattta aaatttaata
    47041 taaaaaagtt ggaagaagct tccaactttt aaaataggtt tctattaaat tagtgggtga
    47101 agtcgagtac catacgtcct tggatttggc ctttttccat ttcgtcgaaa atggcaacag
    47161 catcttctac tggacgtttt tgaacaactg ggactaccag accttctgca ccaaattgga
    47221 aggcttcttc taagtcttta cgagttccga caagagaacc gatgacttgg attccatcga
    47281 ggactgtttt aacgatgctg agttccatca tttcagaagg aagaccaaca gcgacgacgc
    47341 gaccaccagc acgaatggag tcaacagcct ggttgaaggc aactttagac acagcagtta
    47401 cgacagctga atgagctcct ccatcagttt tttctttaat gagtccagct acatcttcaa
    47461 cttcgaggcc gttaatcaca atgtcagcgc ctacttcttt tgcaagggta agtttgtcat
    47521 tgttgatatc gactgcgata acatgagcat tgaatacttt tttagcgtat tgaacagcga
    47581 ggttaccaag tccaccagca ccgtaaagaa caacccattg gcctggttca acttttgctt
    47641 ctttgatagc tttataggtt gttactccag cacatgtgat agaagaagct tgggctggat
    47701 caagtccgtc aggaactttg acagcatagt cagcagttac gatacattgt tcagccatac
    47761 caccgtctac tgagtagcca gcatttttca ctgtacggca aagggtttcg cgaccagttg
    47821 tacagtattc gcaagtgcca catccttcaa agaaccaagc aacgctgacg cggtcaccga
    47881 ctttaaggct tttcacatct ggagcaatct ctttaacgat accgatacct tcgtgcccaa
    47941 gaacacgtcc tgggacttga ccaaagtcac catgagcaac gtggaggtcg gtgtggcaaa
    48001 cgccacagta ttcaacttct acaagtgctt ccccagtttc aagtggacgg agtacttttt
    48061 cttcaatagc aacaccagtg ctttctggat ttacaacaac agctttcata gctatcctcc
    48121 ttgatattga ccgagaacag ggacaacggg actggattga ttttttgtca acagagtcga
    48181 gtgtgacgag ctctcttgta tttatatgtg aagtatatca caaaagaaag ccttttccaa
    48241 ggttttggag acaaaaagta gaacaatcga ttaactggtt gatgagactg tgaaaagagc
    48301 acaaagacca gcttgcaagc tggtcatact cttcgaaaat ctcttcaaac cacgtcagct
    48361 tcatctacaa cctcaaagca gtgctttgag caacctacgg ctagcttcct agtttgctct
    48421 ttgattctca ttgagtatca gtgtaggcta taagaataag tcttgtaggg ttttggcaac
    48481 cccatcttgg tcgttggtaa gggaaatttg ctcatctgca taagggagta gctctggatt
    48541 ggcatttttc atggcataac ctttcccagc aaaagcgagc atttcggtat cattgtgttc
    48601 atctccaaag gcaatcaaat cttttttgtc acgattcatt atcttgagca agtagtccaa
    48661 agcaaaggcc ttgttgacac cttttggggt acattcaagg atattgagcg gacctcccca
    48721 ggtattgata gaaagttgat gctggtagaa ggcgttcatg tcttttgcca aggcatattt
    48781 gtcactggct ctggtctgca agaggataca gttagggtcc ttggttacca attcaggctg
    48841 gaattgatct tcaggctgga aagcttctac accaaatagt ttgggattgg caatctcttc
    48901 attgggattt gtaatgtaga attttttacg atattctcca gcgataaaat cggcttgaat
    48961 gtcctctgaa cgttgaacca tatctagcag atattttttg tctacagtca aacacttttc
    49021 aaaatcccaa acttggtctg gtaaatgagt aagggatccg ttgaagttaa tcataggagt
    49081 gtctaagccc agttcacggt aaaaatcttt tgacatacgg taagggcgac ctgtcgtaat
    49141 aataacctga tggccttttt cagcaacttt tttgatggtt tttttggtaa agtcagaaat
    49201 ttgactgtct gagttgagca gggttccatc caggtcaact gcaataattt ttttcgtcat
    49261 atggaccttt ctagtgtgtt ttcagataag atgtcttcta ttataacaga aagcaggcag
    49321 aaaagcagat tccaaacaaa aaatgaaatt ggattaattt cttaaacaaa tcaaacaaag
    49381 acattgaaaa agtgaatgat aaatgatata attctattat tgttcgtaaa aattaaaagg
    49441 agattgatga tggacaaatt atttaaacta aaagagaacg gtacagacgt tcgtacagag
    49501 gttctcgctg gtttaacaac tttctttgca atgagctata ttctctttgt aaacccacaa
    49561 atactttcac aaacaggaat gcctgctcag ggcgtcttcc tagcgacgat tattggtgca
    49621 gtagcgggta ccttgatgat ggctttttat gctaacttac cttatgccca agcgccaggt
    49681 atgggactca atgccttctt tacctttaca gttgtattcg ggcttggtta ttcttggcaa
    49741 gaagccctag ctatggtctt catctgtggg attatttcat tgattattac cttgacaaat
    49801 gttcgtaaaa tgatcattga atcgattccc aatgctcttc gctcagctat ttcagctggt
    49861 atcggtgtct tccttgccta tgtagggatt aagaatgctg gacttttgaa attcacgatt
    49921 gatccaggca actatactgt tgtaggagaa ggggctgaca aagctcaagc aacgattgca
    49981 gcaaactctt cagcagttcc aggattggtc agctttaata atccagctgt tttagtggct
    50041 cttgcaggac ttgccattac tatcttcttt gtcatcaaag ggattaaagg gggaattatt
    50101 ctctctatct tgacaacaac tgttcttgct attgcagttg gtttggttga tttgtctagt
    50161 atcgattttg ctaataacca tgttggtgca gcttttgaag atttgaagac aatctttggt
    50221 gcagctcttg gttcagaagg tttgggagct ttggtttcag atacagctcg cttgcctgaa
    50281 actctgatgg ccattcttgc cttctcattg acagatattt ttgacacaat tggtaccttg
    50341 atcggtacag gtgaaaaagt tggtattgta gcgacaaatg gtgaaaatca ccaatcagcc
    50401 aaattggata aggctcttta ctctgatttg attggaacga cagtcggtgc cattgcaggt
    50461 acttcaaacg taacgactta tgttgagtct gctgctggta tcggtgcagg tggacgtact
    50521 ggtttgacag ccttggttgt agctatctgt tttgcgattt caagcttctt tagcccactt
    50581 ctagcgatcg taccaacagc ggctacagct ccaatcttga ttatcgttgg gattatgatg
    50641 cttggtagct tgaaaaatat ctattgggat gatatgtctg aagcagttcc tgccttcttc
    50701 acatctatct ttatgggatt cagctactct atcactcaag ggattgcagt tggtttcttg
    50761 acttacactt tgactaagct tgtcaaaggt caagttaaag atgttcatgc catgatttgg
    50821 attttggatg ccttgtttat ccttaactac atcagcatgg ccttataata gaatgaccca
    50881 gggggatttt cccccttttt taatacaaag gagataggtg atgaaagaga aaaatatgtg
    50941 gaaagaattg ttgaatcgtg caggctggat tttggtcttt ttacttgccg tccttttata
    51001 tcaggttccc ctagtggtta cctctatttt gactttaaaa gaagtagccc tgctacagtc
    51061 agggctgata gttactggta tttctattgt ggttctggtg ctatttatta ttggagctcg
    51121 taaaacgcaa ttggcaagtt ttaatttttc tttttttaga actaaggatt tggcacgttt
    51181 gggcttgagt tatttagtca ttatctgttc aaatatactt ggttctatct tgttgcaact
    51241 gtcaaatgag acgacaacag ctaaccagtc tcagattaac gatatggttc agaatagttc
    51301 tctgatttct agcttcttct tgctagcctt gcttgctcca atttgtgagg aaatcttgtg
    51361 ccgtgggctt gttcctaaaa agattttccg aggcaaggag aacttgggat ttgtagtcgg
    51421 tacgattgtg tttgctttat tgcatcaacc aagtaattta ccttctttat tgatttatgg
    51481 aggtatgtcg acagttctat cttggacggc ctacaagacc caacgtttgg aaatgtcgat
    51541 cttgcttcac atgattgtta atgggattgc tttctgtttg ttggctcttg tggtgattat
    51601 gagtcggaca ttaggaattt ctgtttaaaa gtttttatgt aggaaccgac ctctttctac
    51661 tagggaaaga tgaatgcaat cgtgtccatc tttttctttt tatggtaaaa tagaaaaata
    51721 atatggtgaa aagccttgag ggagtgaccg atatgttaag taaaaccaat catgcaaaga
    51781 cagctatttg cggaattatc aatgtaaccc cagactcctt ttcggatggt ggtcaatttt
    51841 ttacgcttga gcaagcgctc cagcaggctc gtaaattgat agcagaagga gccagcatgc
    51901 tagatatcgg tggagaatca actcggccgg gaagtagcta tgttgagata gaaatagaag
    51961 aggaaatcca gcgtgttgtt ccagtgatta aagcgattcg caaggaaagt gatgtcctca
    52021 tttccattga tacttggaaa agtcaggtgg cagaggctgc tttggctgct ggtgccaatc
    52081 tagtcaatga tatcactggt ctcatgggtg atgaaaaaat ggcccatgtg gttgctaatg
    52141 ctggtgcgaa agtagtcatc atgtttaatc cagtcatggc tcgacctcag caccctagct
    52201 cgctcatatt tcctcatttt ggttttggac aagcttttac agaggaagag ttagctgact
    52261 ttgaaaaaat gccaatcgaa gaattgatgg aggctttctt tgaacgagca ctagcgagag
    52321 cagaggaagc tggtattgca ccagaaaata tcctcttgga tccaggaatt ggctttggtt
    52381 tgaccaagaa agaaaatctg cttcttttac gggacctgga taaactacat cagaagggct
    52441 atccaatctt tcttggagtg tcgcgcaagc gatttgtcat caatatcctt gaagaaagtg
    52501 gttttgaagt caatcctgag acggaacttg gtttccacaa tcgagatacg gcttcggctc
    52561 atgtaactag tatcgctgca agacaaggtg tagaagtggt gcgcgtgcat gatgtagcta
    52621 gtcacaggat ggcagttgaa attgcctccg ccattcgtct ggctgatgaa gcggaaaatt
    52681 tagatttaaa acaatataaa taagatgaaa gaaattgaaa acaatcagtg gattgctaac
    52741 taccggacgg accaaccgca ttttggcttg gaacgaatgg tggaactgtt agccttgcgt
    52801 ggcaatcccc atctcaaact caaggtcatc catatcggag ggaccaatgg caaggggtct
    52861 accattgctt ttttgaaaaa tatgctagaa aagctagggc tgagagttgg tgttttcagt
    52921 tcgccctatc tcattcatta cacagaccag attagcatca atggggaatc tatcccagag
    52981 gctagactag aagccctcat ggcagactat cagtctttgc tggaagggga atcggctacc
    53041 aatttgcagg ggacaactga gtttgaaata attacagcta tagcctatga ttactttgcc
    53101 tcagagcaag tagatgtggc tatcatggaa gtgggtatgg gtggactctt ggatagtacc
    53161 aatgtctgtc agcctatttt gacaggaatt acgactattg gattggacca tgtaacccta
    53221 cttggtgaca ccttggaagc catagcagag cagaaagctg gtattatcaa acaaggtatt
    53281 cccttggtga caggtcgtat cgctccagaa gctttggctg tgattgaccg cattgcggaa
    53341 gggaaagatg cgccgagact tgcctacggg gcagattatc atgtcagtca ccaagagagt
    53401 gtggtaacgg gtgaagtctt tgactataca agtgctatca gacaaggtcg cttccaaact
    53461 ggcctgcttg gtttgcacca gatagagaat gctgggatgg ccatagcttt acttgatact
    53521 ttttgtcaag aagttggtcg aaagttacca gctaatatct tgattgctca agctctggaa
    53581 gaaacaagat ggccggggcg tctggaggtc gtgtcaagga accccttgat gatcttggac
    53641 ggggcccaca atccccatgc tatcaaggct ttattggcaa ccttgcaaga acgctttgcg
    53701 gattatagta aggaaatcct ctttacttgt atcaaaacca aggccttgga ggatatgttg
    53761 gacttgctgg gggccatgcc agataccgag cttactctga cacattttga cgatagtcgg
    53821 gcgactgatg aaagcgtgct ggaagaggca gctaagtcta gaaatctcag ctaccaaggt
    53881 tggcaggatt ttctagagca gaaattgaca gataaaaaag aagagaaaaa aacagttagg
    53941 attgtcacag gttccttgta tttcttgagc caagtgagag cctatctgat ggagaggaag
    54001 aacgagaatg gatacacaaa agattgaagc agctgtaaaa atgattatcg aggctgtagg
    54061 agagaacgct aatcgcgagg gcttgcagga aacacctgct cgtgtagccc gtatgtatca
    54121 agagattttt tcaggtcttg gtcaaacagc agaggaacat ttgtcaaaat cctttgaaat
    54181 tattgacgat aatatggtgg tagaaaagga tatctttttc cataccatgt gtgaacacca
    54241 cttcttgcca ttttatggta gagcgcacat tgcctacatt ccagatggtc gtgtggcagg
    54301 cttgtctaag ctagcccgta cggttgaagt ttattcgaaa aaaccacaaa ttcaagaacg
    54361 tttgaatatc gaagtggccg atgccttgat ggactatcta ggtgctaaag gagcctttgt
    54421 tgtcattgag gcggaacata tgtgtatgag tatgcgtggt gttagaaaac caggcactgc
    54481 aaccttgacg acagtagctc gtggtctatt tgaaacagat aaggacctcc gcgaccaagc
    54541 ttatcgttta atggggctat aaaaagaatc cgtttcaagc ggatttttct agaaaggaat
    54601 cattatggat caactgcaga ttaaggattt ggaaatgttt gcctatcatg gtctttttcc
    54661 tagtgagaaa gaattggggc agaaatttgt cgtttcagcc atcctatcct atgatatgac
    54721 caaggcagct acagacttgg atttaacagc ctctgtccat tacggagaat tgtgtcagca
    54781 gtggacgact tggtttcagg aaacgagtga agatttgatt gaaacggtag cctataaact
    54841 ggtggaacgt acctttgagt cttatcctct tgtccaagaa atgaagttgg aactgaaaaa
    54901 accttgggca ccggtgcatt tgtcactaga tacttgctcg gtaaccattc atcgccgcaa
    54961 gcaacgagcc tttatcgccc taggaagcaa tatgggagat aaacaagcaa acttgaagca
    55021 agccattgac aaactgcgag ctcgtggcat ctatattctc aaagagtcca gtgtcttagc
    55081 gacggagcct tggggtggag tggagcagga tagctttgcc aatcaagtgg ttgaggtgga
    55141 aacctggcta ccagcacaag acttgttaga aaccttgtta gccattgagt cagagctggg
    55201 acgggtgaga gaagtgcatt ggggacctcg tttgattgat ttggacttgc tctttgtgga
    55261 ggaccagatc ctttatacag acgacctcat attgcctcat ccttacatag cggaacgcct
    55321 ttttgtcctt gagtccttac aggaaattgc gcctcatttt atccatccga tattaaaaca
    55381 accgatccgt aacttgtatg atgctttgaa aaaatagaaa aactctagtt ttcagttact
    55441 tgcaactgaa ggctagagtt tttaaaatag gtcattttct tctgggagga ggatagtttc
    55501 tctaccgtcc atgtctaaaa ccagtactct tgggggataa cgagggtcga aaggatggtt
    55561 aaagtcaaaa tcaatggctg tagggaggtg ttgacttgaa aagtggaagg taatctttcc
    55621 ttggttatta agcaattgaa actcgagttc ttcttccaat tcaaagacat tttttaagaa
    55681 atggtcgata atataccaaa aagagtcaat gatgtcatca ggcaagctgg taacaatgcc
    55741 aaaactagca gaccgcatgt gggtattggt aaaagccata tctctgtctc ctttcttttc
    55801 ccttatcata cagcaaatag gattaaaaat caagaaaagg tgattttttg aaaaggattt
    55861 taactacagg gaaaaagaag gaaaaaaatt cccaaaaatc taccgaagtt aataggtaaa
    55921 ttcccaaatt aacttgatta tataactttc agttactttg agaagttacc gaaaaatatt
    55981 tttcatatct attgactttt aggggtgaaa tttggtatga tagtaggcgg tattgtttac
    56041 cccatttgaa aggccccgga accttccaaa tacttttcga tgggaaggaa cacccatcac
    56101 cgtaaacaaa aatcgaacta tatataggag aaatcatgaa caaaacaaca tttatggcta
    56161 aaccaggcca agttgaacgt aaatggtacg tagttgacgc aactgatgta ccacttggac
    56221 gtctttctgc agtagttgct agcgtacttc gcggaaaaaa caaaccaaca tttacaccac
    56281 acactgatac aggtgacttc gtgattgtta tcaatgctga aaaagttaaa ttgactggta
    56341 aaaaagcaac tgataaaatc tactacactc actcaaacca cccaggtgga ttgaaacaaa
    56401 tctctgcagg tgaacttcgt tctaaaaatg cagtacgttt gattgagaaa tcagttaaag
    56461 gtatgcttcc acacaataca cttggacgcg ctcaaggtat gaagttgaaa gtatttgttg
    56521 gagctgagca cactcatgct gcacaacaac cagaagttct tgacatttca ggacttatct
    56581 aaggaaagga acaaataaag tatgtcacaa gcacaatatg caggtactgg acgtcgtaaa
    56641 aacgctgttg cacgcgttcg ccttgttcca ggaactggta aaatcactgt taacaaaaaa
    56701 gatgttgaag agtacatccc acacgctgac cttcgtcttg tcatcaacca accattcgca
    56761 gttacttcaa ctgtaggttc atacgacgtt ttcgttaacg ttgtaggtgg tggatacgct
    56821 ggtcaatcag gagctatccg tcacggtatc gctcgtgccc ttcttcaagt agacccagac
    56881 ttccgcgatt cattgaaacg cgcaggactt cttacacgtg actcacgtaa agttgaacgt
    56941 aagaaaccag gtcttaagaa agctcgtaaa gcatcacaat ttagtaaacg ttaattcgaa
    57001 agaattacta tacttataca gagcaccttt cggggtgttc tttttttata ctttcttact
    57061 aaattggtgc aattgacaca gttgttgcga ctttagtcgc ttacaaatgt ggctgcaacc
    57121 tgacaaggtc agttgcctca aaacgttaat caatacaatt atatcaacgt ttcaaagcac
    57181 tcaagagttt acctcatggg tgcttttttt atgttttttg aaaaagttca cctcaaagtt
    57241 taccttattt tcaccttatt gttttagaga ctgtaaggca aattcaccga cggccatagg
    57301 gactacatta gaagtattga cataaatctg tgttgtacct gtgtcgctat gtattagagc
    57361 ttcagaaatg gcttctaagc tcattcctgc ttgtttagcg agcgttgctc cggtatgacg
    57421 tagtttgtgt ggcgtagcgt gtgtaagctc tgggtgtcgt tttctgatag ttttcatctt
    57481 attattgaga tagtcagaat gtaaaggttt attgatattg cctttggtat ctatgtaagt
    57541 aaagatgaat tgttctggat tactgatgat accaaacttt gccagttcat atttttgttg
    57601 ttttttccat gaagtcagaa gttgaagtaa gtcattagaa atagagaaaa tgggaaatgt
    57661 ttccacaata aaacgcatat tatcagatgg ttaatgcgtt ttatatttgg gtttgaggct
    57721 tataaaatag gataagcgta ctgaaaactt agatatgaca aacaaaataa aatttttaaa
    57781 agctacagag aaacatggta taatgtatct aaaggaggta gcatatgtcc ttagatatag
    57841 ataaagaaaa gatgacaatc atgggaatag cttttgaaaa ccgatccgtt tttaagagtg
    57901 tttggtatgc tttaagtaca aatatgattg aaggatggcg acctacggtt agtgatgttg
    57961 aaaaattacg agatgaagct cttgctctgg ggatgactta atgaagcgca actgttatga
    58021 gtcttatgac tatgttgatc cggataattt atataccgat ccgggttctt cagttctaag
    58081 aaataagcag gaaggaaaaa agcacgcgag cttgaatatc gtatgattgc tagtaagagt
    58141 ttgaaattat ttatcaatcc tatcttagtt aatagtttaa aagtagtttg tttcacaact
    58201 gcataagctt agaaaagttg aaaagtgata actctttaat aaactcttgg tttgttaaaa
    58261 gatattttgt ccactacatt ttttcaattg actattattt gtcatagata taacagatag
    58321 aacattgcat tcagaataat gaaaaacgca tcaaaaatgg tgcgttctgt ttttatgtta
    58381 ccataaaagg aggaaaacaa attgaaaatt tttaagggag agttttatcg aatctctgta
    58441 ttaacagaca agctagtaag gttagaatac tctcaaactg gaagttttga ggatagaacg
    58501 acacaactta tctataatag agattttggc caagtttcgt tagattatat cgagacatca
    58561 aacgtactag atattatgac ggactatttt catctgcact ttaataaagg agaatttaac
    58621 gccgaaaatt tatttataga attaaaagga aattttgccg tatatggtag tcgctggtat
    58681 tttggtgaat ctattgaaac gttaaaagga acagctcgga ctctggataa ggcagatgga
    58741 gcaatctcgt tagaagatgg aattattagc cgaaatggta tagccttatt ggatgattct
    58801 caaggattta tttgggatga acaatctggt tatattgaga gagaaaatca aattgacctg
    58861 tatttctttg cctatgggca tgattataga ggagcaatca gagactttta ccatttgact
    58921 ggttcaacac ccttgttgcc aagatatgct ttaggcaatt ggtggagtag atattggcct
    58981 tatacgtcgg atgaatactt ggatttaata gacagatttg caacagagaa aattccatta
    59041 tctatcggtg tgttagatat ggattggcat ataactgaca ttccagctcg ttttggaagt
    59101 ggctggacag gatatagttg gaatagaaac ttaataccaa atccagaaca gttattgcaa
    59161 caacttcatg atagaaagtt aaaactctcc ttaaatgtcc atcctgctga tgggatacgg
    59221 gcttatgaag aagcttatcc tcaaatcgca aaacggttgg ggttaaatgt agaactagaa
    59281 gaacctgcta tttttgattt ttttaatccc tcttttaggg aagcctactt taaagatgtt
    59341 cattatgagc tagaaaagca gggagtagat ttttggtgga ttgactggca acaggggaca
    59401 caaggcatgc tagatccact ttggctttta aaccattatc actatcagga tagttgtaaa
    59461 aatgcagaag gtggtttgat tttatcaaga tatgcaggtc ctggtagtca ccgctaccct
    59521 gttggttttt caggggatac tattatcagt tggaattcct taagatttca accctatttt
    59581 acagcgacag catctaatat cggttatagt tggtggagtc atgatatcgg tggacatatg
    59641 ttgggggatt atgacgaaga gctacaaact agatggctac agtttggtgt ttttagtccg
    59701 attactcgat tacatagttc tagaagtcct tttaatagta aagaaccttg gtttttttca
    59761 gaaacaacat ctaagattat gaagaaatac cttcgtttga gacatcagat gattccttat
    59821 ctatatacca tgaatgtaaa gacacatgag gaaggtgccc cattaatcag tccaatctat
    59881 tatttctatc cagagaatga tgagagctat aatgttccaa accaatactt ttttggaaca
    59941 gaactgatgg tggctcccat tgtagaaaag atggatttga cattccaatc tgcaaaagta
    60001 gatgtatggt tccctgaagg tgaatggtat gacttctttt cagagaaaaa atacacaggt
    60061 ggtgtgaagt taagtgttta tagggacatc tcgactacgc ctgtgtttgc aaaaagtggt
    60121 gcaatcattc ccttggttgg ttctgagata ggtatgggtg ttgatttacc tgaggttgta
    60181 gattggtatg tattcccagg gaaacaacat tcttttgaaa tgcttgaaga tcaaaatggt
    60241 caaagatata aaacaagatt atcaatcgat tgggaaatgg gaatggtaga gttagcatta
    60301 caaggagatt ctagtatcgt tccaagcaat agaaaacata gaattcattt taaaggaacg
    60361 aatgtgtcta taattgaatt gccaaataag aatgatacag ctaaatttga atggaaagat
    60421 aataaaagga catctttaaa tgacgaagtt tttagactac taaagacagc ttctcttcca
    60481 tatgaattaa aagatagatt gttaaatcaa ttcatcaatg cgaaaaactc tcatgactta
    60541 atgaatatct tgcatcatca ggataaggaa ttgagagggc gtttgttgga aatgatattt
    60601 actagccaaa actaattgaa ataattagaa agtcatttgt ttagtgtata tgaagattct
    60661 gtatggtatt cgttatcact ggtcacattg aaaatgtgaa ataagcacct acaacataga
    60721 ctttacaaca cttcatgttt catatcatgg ggtgtttttc tatttaagtc aaagccaatc
    60781 aaaaaatctc actattcatc aggttaaagg aaacctaatc atagtgagat tgtgaattat
    60841 aatagagttt gtatcgcctc ttcaatttgt tttgggtctg tttttgaaga aaagcgttca
    60901 aagacttgcc catcacgacc aatgagaaac ttagcgaaat tccattcgat tcgttttcct
    60961 agtgggccag atttatggtc ttttaaccag acatagagag ggtctgcttc cttaccgttg
    61021 accttaatct tggcaaaacg tgggaaggtg gtttgaaaat gtaggctaca gaaggtgttg
    61081 atttcctctg cgctgccggg tgcttgtccc ataaactgat tgcaagggaa atccaatatt
    61141 tcgaagccct gatcttgata gcgttcatag agttcttgaa gtccctggta ctggggcgtt
    61201 aaaccacatc cagtagcagt gttgacaatc aagagaactt tgccacgata gctatccaag
    61261 ggagttgctt ggttgttttg gttcaaaacg gaaaaatcat aaagtgaagt catgagggcc
    61321 tcttttcttt ttctacattg taacagtttt tacttttttc gtcgagtcgg atggaagata
    61381 ttgttgaaga ataagccctc aatatgatag aaaccgttta caaataactt taaaaatggt
    61441 atgatttaat taaaccggtt tactttgttg ctataaatct ctaatttgag atttagttcc
    61501 tattgatttt acaatatgtt tattggagtg tatacatgca aacaaaaaca aagaagctca
    61561 ttgtgagttt gtcttcactt gttttatcag gatttttatt aaaccattat atgacagttg
    61621 gagcggaaga aacgactacg aataccattc agcaaagcca gaaggaagtt cagtatcagc
    61681 aaagggatac aaaaaattta gttgaaaatg gtgattttgg tcagacggag gacggaagca
    61741 gtccgtggac aggaagcaaa gctcaggggt ggtcagcttg ggtagaccag aagaatagtt
    61801 ctgcagatgc ctcaactcga gtcattgagg ctaaggatgg ggctatcact atctcaagcc
    61861 ctgagaaatt aagggcagcg gttcaccgta tggttcctat tgaagctaag aaaaagtata
    61921 aactgcgttt caagattaaa acagataata aagtcgggat tgccaaagtt cgtatcattg
    61981 agggaaagtg gtaaggacaa gcgattgtgg aattctgcaa cgacgtcagg aacaaaggac
    62041 tggcagacca ttgaagcaga ctatagcccg actttagatg ttgataaaat caagctggag
    62101 ttattctatg aaacaggaac tgggactgtt tcctttaagg atattgagct ggtagaggta
    62161 gcagaccagc cttctgagga ttctcaaaca gataaacagc ttgaggaaaa gattgattta
    62221 ccaattggaa aaaaacatgt tttttctctt gcggactata cttataaggt agaaaatcct
    62281 gacgttgctt cagtcaaaaa tggaatttta gaacctctta aggaagggac aaccaatgtc
    62341 attgtcagta aagatggcaa ggaagtgaaa aagattcctt tgaagattct agcctctgtt
    62401 aaggatgcat acacagaccg tttggatgac tggaatggca tcatcgctgg gaatcaatac
    62461 tatgattcta aaaatgaaca gatggccaaa ttaaaccagg aattggaagg aaaggtagct
    62521 gatagcctat ccagtatttc aagtcaggcg gaccgcatct atttgtggga aaaattttca
    62581 aattataaaa cgtctgcaaa tctgactgcc acttatcgga aattggagga gatggccaag
    62641 caagtgacca atccttcttc tcgttattat caagatgaaa ctgtcgttcg aacagtcagg
    62701 gattccatgg aatggatgca taaatatgtc tacaatagtg aaaagagcat tgttgggaac
    62761 tggtgggatt atgaaatcgg tacacctcgt gccatcaaca ataccttgtc tctgatgaaa
    62821 gaatacttct ctgatgagga aattaaaaaa tatacagatg tgattgaaaa atttgtacca
    62881 gatcccgaac atttccgaaa gacgactgat aacccattta aggctctagg tggaaactta
    62941 gttgatatgg gaagagtaaa agtaatagct ggtttactgc gtaaagatga tcaagaaatt
    63001 tcttctacca ttcgctcgat tgagcaagtg ttcaagttgg tagaccaagg tgaaggtttt
    63061 tatcaagatg gatcctatat cgaccatacc aatgttgcct atacgggtgc ttatgggaat
    63121 gttttgattg atggcctgtc tcaactgttg ccagtcattc aaaagaccaa gaatccaatc
    63181 gataaagata aaatgcaaac catgtaccac tggattgata aatcgtttgc tcctttgctg
    63241 gtgaatggag agctgatgga tatgagtcgt ggacgctcga tcagtcgtgc aaatagcgag
    63301 gggcacgtgg ccgcagtaga agtactaaga gggattcacc gaatagcgga tatgtctgaa
    63361 ggagaaacca aacaacgttt gcagagtctt gtgaagacca ttgttcaatc ggatagttat
    63421 tatgatgtct ttaagaattt gaagacttat aaggatatca gtttgatgca atccttgtta
    63481 agtgatgcag gagtcgcaag tgttccaaga acaagttacc tatctgcctt taacaagatg
    63541 gataaaacag ccatgtacaa tgcagagaaa gggtttggat ttggcttgtc actcttttcc
    63601 agtcgtacct tgaattacga acatatgaac aaggaaaata aacgtggttg gtatacgagt
    63661 gatgggatgt tctatcttta caatggcgat ttgagtcact atagcgatgg ctactggcca
    63721 acagtcaatc catataagat gcctggtaca acagagacgg atgctaagag agcggatagc
    63781 gatacaggta aagttttacc gtctgctttc gttggaacga gcaaactaga tgatgccaat
    63841 gcgacagcaa ccatggattt caccaactgg aatcaaacat tgactgctca taagagctgg
    63901 tttatgctaa aggataagat cgccttttta ggaagcaata tccaaaacac ttcaacagat
    63961 actgctgcaa ctacaattga ccagagaaaa ctggaatcag gtaatccata taaagtctat
    64021 gtcaatgata aagaagcctc ccttacagaa caagaaaagg attatcctga aacccaaagt
    64081 gtctttttag aatcgtccga ttcgaaaaag aatattggtt actttttctt taagaagagt
    64141 tcaatcagta tgagtaaggc tttgcaaaag ggagcctgga aggatatcaa tgaaggacag
    64201 tcagacaagg aagttgaaaa tgaatttctt acgattagtc aggctcataa gcaaaatggg
    64261 gattcttatg gctatatgct catccctaac gtggatcgtg ccaccttcaa tcaaatgata
    64321 aaagagttag aaagtagcct catcgacaat aacgaaaccc ttcagtctgt ttatgatgcc
    64381 aaacaaggag tttggggcat tgtgaaatat gatgattctg tctctactat ttccaaccaa
    64441 ttccaagttt tgaaacgtgg agtctatatc attcgaaaag aaggggatga atataagatt
    64501 gcctactata atcctgaaac ccaggaatca gctccagatc aggaagtctt taaaaagcta
    64561 gagcaagcaa ctcagccaca agtacagaat tcaaaagaaa aggaaaaatc tgaagaggaa
    64621 aagaaccatt cggatcaaaa gaatctccct cagacaggag aaggtcagtc aatcttggca
    64681 agtctagggt tcttgctact tggggcgttt tatctattcc gtagaggaaa gaacaactaa
    64741 tttgttcatc atctagatga attacatgaa actgtggaaa atagaaaaat ccgaagaagg
    64801 ccaaatatct tcggattttt cttttaaaaa agataagttg atacttatcc ttttttactt
    64861 cattatgtga ctatagcgtt ttgaaactag aataggacgt tataactgct aaaagatttc
    64921 tataaattca tttgattttc ctaatcaatt tgttcgtatc ctatttcact ccactatatt
    64981 agtccgtctc gctccgtgag gtgcgcgtcg aaggttatac caaaaaaact ccaaacgcga
    65041 tacaataaag gtgttcaatc caattgtaaa gcgaaaggag aaaaaatatg gcacaaaagg
    65101 ctcatagttt atctcacaca aagtggaggt gttctatcac attgtgttca cccctaagta
    65161 tagacgaaaa gtcatctata atcaatatag aagtagttta ggcgaaatat ttcattgctt
    65221 gtgtagttat aaaggtgttg aaatgatcga gggtcactta atgccagacc atgtacacat
    65281 gttagtcagt attccgtcga ggctaagtgt ttcaagtttt atggggtatt taaaaggcaa
    65341 aagtgcactc atgatgtttg acaaacacgc caatctcaag tacaagtttg ggaatcggca
    65401 tttctgggtg gaaggttatt atgtaagtac agtagggctt aataaagcta caattaagaa
    65461 atatagtcaa gattaaagaa attatccagt ggatgatttc ttcacgagta tgaaaatttg
    65521 agaactagta aagtatgata tatagtaaaa tgaaataaga acaggataaa atcaatcagg
    65581 acagtcaaat cgatttttaa caatgtttta gaagtagagg tgtactattc tagtttcaat
    65641 ctactatagc actagataaa ttgagtgtaa aagaatatga ggatcccttt agggatagtg
    65701 gtaagtaata ccaaagtctc ttaaagaggc aagtgacgag tcaagagcaa taaggcttga
    65761 acaacgtgaa agccagcgtc tttaggcgct ggctgatgat ttgggcttat agctctgaga
    65821 taaaccaccc gttagacggg tagttatgat tttatctgag tgtaatatac tgttgggcaa
    65881 tctcgctgat gcggtcaaag ttgccttggg aagcgagttt attgagttcg ccaccaattc
    65941 caacggcatc tgcaccagca gcgaaccatt gagggatgtt gtttaggccg actcctccgg
    66001 ttaccattac ggaaacttgt gggatcggtg ccttgactgc agagatatat gctggactga
    66061 gagtactacc tgggaagagt ttgatgattt cactaccggc ttcaagtgca gtcgtgatct
    66121 ctgtgagggt aatacagcct ggaatgtacg gtgtgctgta gagattgcac attttcgcag
    66181 tttcagcatg gaaagatgga gaaacaacgt aatttgctcc agctagaatg gcatctctag
    66241 cagttacggc atcaagcaca gtacctgcac cgatacaaac actctgatcg tcctgataca
    66301 agtctacaag ttccttgatg atttgtcctg catactgatt ggtataggcg atttcaatag
    66361 ctttgatacc gcccttgata caagcaatcg aggcttgtag tccttcttcc tttgtatttc
    66421 ctcgaatgac agcgacaatt ttctgttttt ttagttcaat aatcgtatct gatttggtca
    66481 tgtaattctc ctaacgaatg atatcttgtg catttgccag taaattttca atactagttg
    66541 cggaagtgga gagatggtct cctggaagag tgcatttgag agttgcgctc gcaactgcaa
    66601 agtcaatggt agtttttagg gaggaatgat ggagtagttg gtaaagggca ccagatataa
    66661 aggcatcccc gctaccaatt cgttgataga ctgcagtttt tagttggaca gactcttcaa
    66721 atcgttcttc cagagcatag gcttgataga catttttgtc ttgctcatca ctagagcgga
    66781 gggtatggaa aatggccttg aaaccatagg cttcttttaa aagtcgcatg cgattttcca
    66841 cctcttctag gctagcactg tctcttggaa acatctctag attttggtca tcaatcatga
    66901 gaggatcaat accgaagcaa tagtcagtaa aacgtgcaaa cttagaaaat tcatacttgg
    66961 cttctaggac tgaaatcatc tttgttctca gattgagatc cattgaaacg acaattcctc
    67021 ggcgcttggc ttcttccaag agtaggagaa ggatcgcacg gacctcttga ccgatagcta
    67081 cggtgattcc actaaaatga aaatggctaa tcccctgaaa gagagaatcc atatctagca
    67141 tgtttggccg aatctggctg atactcgtat gcttacgatc gtagaaaact tcactttgac
    67201 gacaaccaaa gccgttctcc aaatagtaga ggccgattcg atcgccaagc cgacagattg
    67261 aactggtatc gatttggtgc tgtttcaaga atgtgagaaa acgatctcca atctcgttgg
    67321 cagggagtgc ggtaaagact ttcgttgaga tacccagggc ttgcaaatta caagcgatgt
    67381 taatttctga tccgccaaaa taagtcgaac tggcaacatg atcgccgata ctggtggcat
    67441 ctaatggtga gattcgaatt aatggttctc caaacagtaa tattttcgtc atccattagt
    67501 tcctttctgg tttagaatag ctttacttgg ctaatacttc tttcaaataa gcagcaactt
    67561 catcatcttg gcagttttca aagaagtatt cttggaagta tttgccagag atggtgtctt
    67621 tgaggaagtc ttggtcgatt attttaagga tggtcatcaa atcattgtgg gtgatttgtt
    67681 tcacctcgtt taagatacga gcgttgcgtt gttcagggat tacacgttct cttgggtagc
    67741 caccgcccat ttcttcagca aataagcgtt caaacatcaa tttgagggtc agttctgccc
    67801 cccagccaaa tcctttggca taagggatag acaaggcgtt accaccattg atttgagaat
    67861 aaaggtaagc gtcagttggg tccactgcta gaccacagac aacaccaggg aagctgttta
    67921 aagcaagcat agcccctaca cccgtaccac agccggtaac aacaaagtca actgcctttg
    67981 tatttaaaag gatggcagcc attagtccgt tctgcacata agttaattga ctttctcctt
    68041 cttctccacg cataccatag ttaaataatt ggtagccttt tttatctgtc gcttctttta
    68101 gactatcgta aataatgtga ttcttgctag cttgactatt ttcattgatt aatgcgattt
    68161 tcataagatc ttctttctat ttttactcag gttgttttcc gatgtaggct aagataccgc
    68221 catctacata taggatgtgg ccattgacaa aattgctggc atcactagcg agaaagacag
    68281 cagggcccat caaatcttca ggatttcccc aacgtgcagc aggtgttttt gcaatgatga
    68341 actggtcaaa tgggtggcga gaaccatctt cttgcaattc acgaagaggt gctgtttgag
    68401 gagtggcaat ataacccggt ccaattccgt tacattggat attggctcca ccgtattcag
    68461 acgcaatgtt gcgggtcaac attttcaagc cccctttagc agcagcataa gcgctaactg
    68521 tttcacgtcc cagttcgctc atcatcgaac aaatattgat aatctttcca tgccctttct
    68581 ttatcataga aggaataact gcctttgaaa cgataaatgg tgcgtttaag tcaatatcga
    68641 tgaccttacg gaaatcagcg gcgctcattt cgcacattgg aactcggcgg ataataccag
    68701 cgttattaac gaggatgtca atgacaccaa cctcttgttc gatttgcttg accatggctt
    68761 ggataccgtc ctcgtctgtc acgtcacaga catatccatg ggcttcgatg ccaacttcac
    68821 gataagcttc aatcccttta ttgaccagat cttgattgat atcgttaaag acaatagtag
    68881 cgccggcttc agcgtaggat ttggcaatag caaatccaat tccataagaa gcgccggtga
    68941 tgagagcaat ttttcctttt aaagaaaact gctcaattga gaatgatgta tttgtcattt
    69001 gatacttcct ttcaaatttg ttaagacttc tctataacca aattatattc
//
LOCUS       DAVHSY010000008        62857 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.008, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000008 DAVHSY010000000
VERSION     DAVHSY010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62857
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.008"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(<1..1069)
                     /locus_tag="VVR43_000643"
     CDS             complement(<1..1069)
                     /locus_tag="VVR43_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6149040.1"
                     /translation="MSLRNKIEQHIKELEGGKFQKLGDAYLSRKYNFNIVSLGSQEGT
                     DKTTKGIPDSYAVENGKYVYIMYGTHKSVISKLEGDIQSVKKKILEENIAEDKVGRLI
                     CCHTSSNITIKQKEDLEKMAEPYHLELIGINEIANDLTKIDFQYLAKEYLSISESTEQ
                     VWSINDFIRIHDESKTNAPISNDYIGDVSEIINTIKSSEKRIFLISAKPGTGKTRLAI
                     EICSLLDRNKYNIICVKSNNQDIYQDVKRNLNLHKENIVFIDDVNTTQNYISTLGLLN
                     TTSNIRFILTVRDYAKKDVINNIKVYGYNNIEPELIKDDNFKELLNQFSRNDFTNQEI
                     EHIKTISKSNPRIAVIAAKLSS"
     gene            complement(1316..1684)
                     /gene="rplL"
                     /locus_tag="VVR43_000644"
     CDS             complement(1316..1684)
                     /gene="rplL"
                     /locus_tag="VVR43_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU6149041.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            complement(1760..2260)
                     /locus_tag="VVR43_000645"
     CDS             complement(1760..2260)
                     /locus_tag="VVR43_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU6149042.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     misc_feature    complement(2299..2434)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(2510..3769)
                     /locus_tag="VVR43_000646"
     CDS             complement(2510..3769)
                     /locus_tag="VVR43_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU6149043.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKALGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     gene            complement(4026..5774)
                     /locus_tag="VVR43_000647"
     CDS             complement(4026..5774)
                     /locus_tag="VVR43_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149044.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRNLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(5776..7500)
                     /locus_tag="VVR43_000648"
     CDS             complement(5776..7500)
                     /locus_tag="VVR43_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149045.1"
                     /translation="MKYLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLIQLILGLYPVNKGRIDL
                     YLDGLSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            complement(7558..8496)
                     /gene="msrB"
                     /locus_tag="VVR43_000649"
     CDS             complement(7558..8496)
                     /gene="msrB"
                     /locus_tag="VVR43_000649"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU6149046.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(8687..8767)
                     /locus_tag="VVR43_000650"
                     /pseudo
     CDS             complement(8687..8767)
                     /locus_tag="VVR43_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(8837..9706)
                     /locus_tag="VVR43_000651"
     CDS             complement(8837..9706)
                     /locus_tag="VVR43_000651"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU6149047.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPIIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(9708..10994)
                     /locus_tag="VVR43_000652"
     CDS             complement(9708..10994)
                     /locus_tag="VVR43_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU6149048.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDHDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(11145..11882)
                     /gene="mecA"
                     /locus_tag="VVR43_000653"
     CDS             complement(11145..11882)
                     /gene="mecA"
                     /locus_tag="VVR43_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU6149049.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(12082..13116)
                     /locus_tag="VVR43_000654"
     CDS             complement(12082..13116)
                     /locus_tag="VVR43_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU6149050.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(13145..14578)
                     /locus_tag="VVR43_000655"
     CDS             complement(13145..14578)
                     /locus_tag="VVR43_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU6149051.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLVVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(14594..15580)
                     /locus_tag="VVR43_000656"
     CDS             complement(14594..15580)
                     /locus_tag="VVR43_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6149052.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(15582..16685)
                     /locus_tag="VVR43_000657"
     CDS             complement(15582..16685)
                     /locus_tag="VVR43_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU6149053.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTRNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(16675..17520)
                     /locus_tag="VVR43_000658"
     CDS             complement(16675..17520)
                     /locus_tag="VVR43_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU6149054.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKNFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDILPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDTVIADMDKSYTKYK
                     GEYGG"
     gene            complement(17799..19073)
                     /gene="psr"
                     /locus_tag="VVR43_000659"
     CDS             complement(17799..19073)
                     /gene="psr"
                     /locus_tag="VVR43_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU6149055.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(19070..19918)
                     /gene="pheA"
                     /locus_tag="VVR43_000660"
     CDS             complement(19070..19918)
                     /gene="pheA"
                     /locus_tag="VVR43_000660"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU6149056.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSTEEYGLELIA
                     EDIQEMEANLTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(19915..20391)
                     /locus_tag="VVR43_000661"
     CDS             complement(19915..20391)
                     /locus_tag="VVR43_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU6149057.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDTNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRHVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(20384..21667)
                     /gene="aroA"
                     /locus_tag="VVR43_000662"
     CDS             complement(20384..21667)
                     /gene="aroA"
                     /locus_tag="VVR43_000662"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU6149058.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGASVIIEKECTRNHTEDMLKQFGGHLSVDGKKIIVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(21759..22097)
                     /locus_tag="VVR43_000663"
     CDS             complement(21759..22097)
                     /locus_tag="VVR43_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU6149059.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(22108..23211)
                     /locus_tag="VVR43_000664"
     CDS             complement(22108..23211)
                     /locus_tag="VVR43_000664"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU6149060.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(23221..24387)
                     /gene="aroC"
                     /locus_tag="VVR43_000665"
     CDS             complement(23221..24387)
                     /gene="aroC"
                     /locus_tag="VVR43_000665"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU6149061.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINGDLKRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVVNKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKYRDYTKNY"
     gene            complement(24397..25464)
                     /locus_tag="VVR43_000666"
     CDS             complement(24397..25464)
                     /locus_tag="VVR43_000666"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU6149062.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCLAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTELDGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGVRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEKKGLMPAGITQSITDMCQKFGLPVDYENWDVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(25483..26337)
                     /locus_tag="VVR43_000667"
     CDS             complement(25483..26337)
                     /locus_tag="VVR43_000667"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU6149063.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLYALENVSELQARIVESDLLVNATSVGMDGQSSPVPESINL
                     PETILVADIIYQPFETPFLKWARSQGKPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(26327..27004)
                     /locus_tag="VVR43_000668"
     CDS             complement(26327..27004)
                     /locus_tag="VVR43_000668"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU6149064.1"
                     /translation="MKLIVSVMPRSLEEAQALGATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(27001..28164)
                     /locus_tag="VVR43_000669"
     CDS             complement(27001..28164)
                     /locus_tag="VVR43_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU6149065.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(28849..30483)
                     /locus_tag="VVR43_000670"
     CDS             complement(28849..30483)
                     /locus_tag="VVR43_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149066.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(30464..31213)
                     /locus_tag="VVR43_000671"
     CDS             complement(30464..31213)
                     /locus_tag="VVR43_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149067.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            31392..32846
                     /locus_tag="VVR43_000672"
     CDS             31392..32846
                     /locus_tag="VVR43_000672"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU6149068.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(32936..35554)
                     /gene="alaS"
                     /locus_tag="VVR43_000673"
     CDS             complement(32936..35554)
                     /gene="alaS"
                     /locus_tag="VVR43_000673"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU6149069.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVTQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTTSLIFAETPFYAEMGGQVA
                     DHGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAIAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(35576..36061)
                     /locus_tag="VVR43_000674"
     CDS             complement(35576..36061)
                     /locus_tag="VVR43_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU6149070.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(36336..36575)
                     /locus_tag="VVR43_000675"
     CDS             complement(36336..36575)
                     /locus_tag="VVR43_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149071.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILSHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(36820..37890)
                     /locus_tag="VVR43_000676"
     CDS             complement(36820..37890)
                     /locus_tag="VVR43_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6149072.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKLEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(37887..38660)
                     /locus_tag="VVR43_000677"
     CDS             complement(37887..38660)
                     /locus_tag="VVR43_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6149073.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(38657..39463)
                     /locus_tag="VVR43_000678"
     CDS             complement(38657..39463)
                     /locus_tag="VVR43_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6149074.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(39444..40601)
                     /locus_tag="VVR43_000679"
     CDS             complement(39444..40601)
                     /locus_tag="VVR43_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149075.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(40660..41610)
                     /gene="murB"
                     /locus_tag="VVR43_000680"
     CDS             complement(40660..41610)
                     /gene="murB"
                     /locus_tag="VVR43_000680"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU6149076.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(41722..42474)
                     /locus_tag="VVR43_000681"
     CDS             complement(41722..42474)
                     /locus_tag="VVR43_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEU6149077.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLVYIIYGLAMAAFFEETARLVFFKWLEKKI
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLTAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLIAYGTKEIFCKKS"
     gene            complement(42484..43215)
                     /gene="budA"
                     /locus_tag="VVR43_000682"
     CDS             complement(42484..43215)
                     /gene="budA"
                     /locus_tag="VVR43_000682"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU6149078.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGTGEQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELEERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     VGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            43357..44628
                     /locus_tag="VVR43_000683"
     CDS             43357..44628
                     /locus_tag="VVR43_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU6149079.1"
                     /translation="MKRQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFMAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(44648..45463)
                     /locus_tag="VVR43_000684"
     CDS             complement(44648..45463)
                     /locus_tag="VVR43_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU6149080.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(45620..46273)
                     /gene="phoU"
                     /locus_tag="VVR43_000685"
     CDS             complement(45620..46273)
                     /gene="phoU"
                     /locus_tag="VVR43_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU6149081.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(46285..47043)
                     /gene="pstB"
                     /locus_tag="VVR43_000686"
     CDS             complement(46285..47043)
                     /gene="pstB"
                     /locus_tag="VVR43_000686"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU6149082.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(47056..47859)
                     /gene="pstB"
                     /locus_tag="VVR43_000687"
     CDS             complement(47056..47859)
                     /gene="pstB"
                     /locus_tag="VVR43_000687"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU6149083.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(47870..48754)
                     /gene="pstA"
                     /locus_tag="VVR43_000688"
     CDS             complement(47870..48754)
                     /gene="pstA"
                     /locus_tag="VVR43_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU6149084.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(48744..49661)
                     /gene="pstC"
                     /locus_tag="VVR43_000689"
     CDS             complement(48744..49661)
                     /gene="pstC"
                     /locus_tag="VVR43_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU6149085.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(49661..50539)
                     /gene="pstS"
                     /locus_tag="VVR43_000690"
     CDS             complement(49661..50539)
                     /gene="pstS"
                     /locus_tag="VVR43_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU6149086.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(51113..52417)
                     /locus_tag="VVR43_000691"
     CDS             complement(51113..52417)
                     /locus_tag="VVR43_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU6149087.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCVSLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(52418..53191)
                     /locus_tag="VVR43_000692"
     CDS             complement(52418..53191)
                     /locus_tag="VVR43_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU6149088.1"
                     /translation="MESKFEFAKGLVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(53181..53459)
                     /locus_tag="VVR43_000693"
     CDS             complement(53181..53459)
                     /locus_tag="VVR43_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU6149089.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(53459..53860)
                     /locus_tag="VVR43_000694"
     CDS             complement(53459..53860)
                     /locus_tag="VVR43_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU6149090.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(54070..54687)
                     /locus_tag="VVR43_000695"
     CDS             complement(54070..54687)
                     /locus_tag="VVR43_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU6149091.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETVQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(54677..55450)
                     /locus_tag="VVR43_000696"
     CDS             complement(54677..55450)
                     /locus_tag="VVR43_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU6149092.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     TGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(55461..56198)
                     /locus_tag="VVR43_000697"
     CDS             complement(55461..56198)
                     /locus_tag="VVR43_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU6149093.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(56203..57333)
                     /locus_tag="VVR43_000698"
     CDS             complement(56203..57333)
                     /locus_tag="VVR43_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU6149094.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(57417..57806)
                     /locus_tag="VVR43_000699"
     CDS             complement(57417..57806)
                     /locus_tag="VVR43_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU6149095.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(57822..58205)
                     /locus_tag="VVR43_000700"
     CDS             complement(57822..58205)
                     /locus_tag="VVR43_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU6149096.1"
                     /translation="MLEVAYILVALAVIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(58206..58994)
                     /locus_tag="VVR43_000701"
     CDS             complement(58206..58994)
                     /locus_tag="VVR43_000701"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU6149097.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(58987..59922)
                     /locus_tag="VVR43_000702"
     CDS             complement(58987..59922)
                     /locus_tag="VVR43_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU6149098.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(60052..60228)
                     /locus_tag="VVR43_000703"
     CDS             complement(60052..60228)
                     /locus_tag="VVR43_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU6149099.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(60368..61075)
                     /locus_tag="VVR43_000704"
     CDS             complement(60368..61075)
                     /locus_tag="VVR43_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU6149100.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            61226..62254
                     /gene="queA"
                     /locus_tag="VVR43_000705"
     CDS             61226..62254
                     /gene="queA"
                     /locus_tag="VVR43_000705"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU6149101.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFS
                     FGDAMFIY"
BASE COUNT        18636 a        14193 c        11812 g        18216 t
ORIGIN      
        1 agctagataa ctttgctgca atgactgcaa tacgcggatt gcttttagat atcgttttta
       61 tatgttcaat ttcttgattg gtaaaatcgt ttcgagaaaa ttgattgagt aattccttaa
      121 aattatcatc ttttataagt tctggctcaa tattattgta cccataaact ttaatattat
      181 tgattacatc ttttttagca taatcacgta ccgtaagaat aaaccgaata ttactagtcg
      241 tgttcagtag cccaagtgta gaaatataat tttgtgtagt attaacatca tcaataaaaa
      301 caatattttc tttgtgtaaa tttagattgc gttttacatc ttggtaaata tcctgattat
      361 tgctcttgac acaaataatg ttatatttat ttcgatccag caaagagcaa atttcaattg
      421 ctaatctagt tttccctgtt ccaggcttag cagatattaa gaagattcgt ttttcacttg
      481 atttaatggt atttataatt tcacttacat ctccaatata gtcatttgat ataggagcat
      541 tagttttact ctcatcatga attcttatga agtcattgat agaccaaact tgctctgtag
      601 attcactgat tgatagatac tcttttgcta aatattgaaa atctatcttt gtaagatcat
      661 tagcaatttc attaattcca atcaattcta gatgataagg ctcagccatt ttttctagat
      721 cttctttttg tttaattgtt atatttgaag aagtatgaca acaaataagt ctcccaactt
      781 tatcttcagc aatattttcc tctaaaattt ttttcttaac tgactgaatg tctccttcta
      841 atttagatat tacagactta tgggtgccat acataatata aacatattta ccattttcga
      901 cagcgtaaga atctgggatc cctttagttg ttttatctgt tccttcctgt gagcctaatg
      961 aaacaatatt aaaattgtat tttctactta ggtacgcgtc acctagtttt tgaaacttcc
     1021 ctccctctag ctctttaata tgttgctcaa ttttatttct taaactcatt ataaaaacct
     1081 ttccagataa gtatttcaac ataattatat cacactagtc aaaaccataa ggtatagttt
     1141 aattaacaaa ctcttgtact acgttaattt agagtagtaa accaattata caaaaattat
     1201 ttatttccta aacaactata taaaaagttt gccccttttt aaacaaaaag aaaaaccgct
     1261 actcctaaga atagcggttt aatcatgttt ttaagctact aatgtagttg ctctattatt
     1321 taagagtaac tgaagctcca gcttcttcca atttagcttt gatttcttca gcttctgcag
     1381 ttgcaacgcc ttctttaaca agtgctggtg caccgtcaac aagttcttta gcttctttaa
     1441 gaccaagacc agtgatttca cgtacaactt tgataacacc aacttttttg tcgcctgcag
     1501 atgtcaattc aacgtcgaat gaatctttag cagcaccagc atcagctgca tcagctgcag
     1561 caacagctac aggagcagct gcagttacac caaattcttc ttcgatagct tttacaaggt
     1621 cgttcaattc aaggattgaa gcttctttaa tttcagcaat aatgttttca atgttcaatg
     1681 ccattgttat ttcctccaaa taagttttaa attttataat agtttttttc gtagctaggc
     1741 tacgctatgt agcttaagat taagccgcgt cttctttgct ttctgcaacc gctttgactg
     1801 caagagcaac gttgcgcact ggcgcttgaa gtacagaaag gagcatagaa agaagtcctt
     1861 cgcggtttgg aagagttgca agtgcaagaa tctcttcttt agatgcgaca gcgccttcga
     1921 ttgcaccacc tttaatttca agtgcttcag cgtttttaga aaagtcgttc aagattttcg
     1981 ctggtgcgat aacatcttca ttagaaaatg ctactgcaga tggtccaaca aatacagatg
     2041 caagatcttc aagaccagct ttttcagctg cacgacgcaa gattgagttt ttaataactt
     2101 tatactcaac ttcgcttcca cgaagctcac gacgaagaac tgtatcttgc tcaactgtca
     2161 aaccacgagc gtctacaacg acgatagatg cagcagcttt cattttttca gctactacgt
     2221 caactagttc cgctttttta gcaataattg cttcactcat tagtgtgttc acctccgtaa
     2281 ttattttgct tggggaattt ttcaaaaaga aaaacgcgcc caaacctaga cacgaaagta
     2341 caatacgctt ctttttacat gatacgtctt gtcctcggta ggatatttat gagtcgagct
     2401 cccctactgt cttaggcagt ttttttaaac cgtatataag tatagcatag tcaaaaaaag
     2461 aatgcaagat ttttgcaaac tttttttaaa atttttcgtg atttttcttt taaagttcta
     2521 ctgtcaggac ttgaccttgc ttaacaacct gttctccggc gatataaaca tcatctacat
     2581 cactagattt aactgcataa accaggtgag acagcatatt ttcctgaggt tggagatgaa
     2641 ttttcccttg tggttgaatg accagaaaat ctgcttgctt gccgacttcc agacttccta
     2701 tctgattttc cattccaagg gccttagccc cttcgattgt cagtaccttg agagctgttt
     2761 cgattggaaa ctggctggca tccccacttt tcatcttctg aagaagagct gcagtccttc
     2821 cttcctcaaa catatctaga ttgttattgg aagcaaccga gtcagtcgca attccgactg
     2881 ctactcccgc tttttggagc tggataattg gagcaattcc tgatgccagt ttgaggttac
     2941 tgataggatt gtgggcgata gccacttgag aagatgccaa gcgttcaatt tctctctcgt
     3001 ttaattcgac cccgtgagca aatacggacg gatgatctaa ataacccagt tcttcaagaa
     3061 aagcaagggg gcgtttgccg tatcgtttga ggataattcc tgactcctcc ttggtctccg
     3121 ccacatggac atggagcgga atatttagct cttttgccat ttccaaactc gcttccagca
     3181 agtctctact gcagctatac ggagaatgag gtgctaccat aaccttgaaa tttggatttt
     3241 tatattttaa gatttcgtct atgatggatc gagttctgct tatagtctca gcagttgttt
     3301 ctgtctctga agaaaagaga gtcggagaaa aataacaacg catcttggaa gttttcacca
     3361 cctgataaat ttgctgaata tccacaccat tgggattata catatcgtta aaggttgttg
     3421 ttcctgactg gagcatctct gtcagggctt ctttgaccgc attggtagtc atgtcgggag
     3481 taaactcaga ttctgctggc cagatatagt cattgagcca ttcatggaga ttgctgtcat
     3541 ctcggatccc tctcagacct gtcattgcag aatgggtgtg acaattgacc aaaccaggca
     3601 taatccaagc tccctgatag tctataatct gctcagcttg ctctaaaaac gctggcttat
     3661 cttgaccgac atagacgatt tgagaatcct tgactgctaa gattccatca agataaacat
     3721 ggaaatcttg atcacaagtc acgatattta catgctgaaa gactttcatt ataggctcct
     3781 tttctaaaag acaagtttta ctctcttcaa accacttcag attcactttg ccgtaggtgt
     3841 ggttactgac ttcgtcagtt ctatctacaa cctcaaagct gtgctttgag caacctacgg
     3901 ctagcttcct agtttgctct ttgattttca ttgagtatta cagtaaacaa tttttctagc
     3961 tattgtaaca aaaaagtcac tcgaaggcaa cttttttcgt ccataaactt tcaaaagaga
     4021 atggcttatt cagaactaaa agccgcagct ttttgcattt ggtaatactt accctttcta
     4081 tccatgagtt cttgatggtt accatattca acaatatcac catctactaa gacaagaatt
     4141 aaatccgcat cctgaatggt tgacaaacgg tgagcaatga tgaagcttgt gcggcccttc
     4201 atgagttttg caaaggcatc ctgtaccagc acttctgtcc gtgtatcaat ggaagaagtt
     4261 gcctcgtcta agataagaat ctttggaata gccagaaaga ctcgggctat ggtcaagagc
     4321 tgagcttggc cgacagagag agattctcca gcattttcca acttggtatc gtatccctgt
     4381 ggcaactgtt ggatgaaaaa gtctgcatta gctgctttgg cagcagcaat tacttgctct
     4441 cgactggctt caggattgcc aaaggcaata ttatcatgaa tggtcccttg tgtgagccag
     4501 gtttcttgaa gcaccatacc aaactgctgt ctcaatgata ctcgtgtata atcataaatg
     4561 gattgcccat ccagcaagat atctcccgag ctaatgggat aaaaacgcat aaggagattg
     4621 ataagagttg attttccagc acctgtagga ccaacgatgg ctaccttact accagctgga
     4681 atatcgatag acaagtcctt aatcaaaatt ttttcaggat ggtagccaaa agagacatgt
     4741 ttaaaggaaa tagctccctt aacttggtca ctggtcaaga cttccttacc tgtttcagcc
     4801 acttcagggc tatctaagac tccatagata cgctctacgc aagccagagc actttgcaac
     4861 tcagctagca ctgaagaaat atcgttaaag ggcttggtgt attgctgaac atagttcaaa
     4921 aaagtcacta aacgaccgac ggtcaaggct gaacccatca tgatacgata agctcctact
     4981 ccagctaaaa gggcataaat gagtgcattt acaaagcgag tcgaaggatt gaccgttgaa
     5041 gaataaaaga tggctgactg agaatagcct gagtagttgt catgagcctc acgcaatctt
     5101 tggataaatt ctgtttgagc attgaaggac tggattatag tctgctgact aagcgattct
     5161 tcaatcaact gagtctgaat tcccctcgtc tctgtttgct tctggaagag atgataggat
     5221 ttcttggcaa taaagcgtga aatcaccatg gacagtggcg tcaacagcaa gactaagaga
     5281 gtcatgagga gatgaatttg gagcatggct agaatactaa ccaaaatcat caaaacacca
     5341 atgaaaaatt ggttaaaaat catggtcaag ccagctgcca actgttcgat atccgtggtt
     5401 acacgactga ccatctctcc attgccttgc cgatccgcaa aagcaatcgg taaccgatgg
     5461 agtttatgga tgattcgctc tcgtaaattt ctggtataag agaagattag acgattatag
     5521 aggagaggat tggcccattg taccagagta tttcctatta ccaccaagag catctggaga
     5581 aaaatctgcc aaaaaactgg tgatgaacca gccactagga cttggtcaat gacctgccca
     5641 atcagaatag gtaggtaaat tgataagcca acttgggcaa tagttcctag aaaggctagg
     5701 aaaaggagga aaggatggct tgctaaatct acggctaaac gtttgagcgt ctggtttaca
     5761 gtttgtcgtt tcattctagt cctcctttcc atgttgggat gcattgattt cacaatagac
     5821 ttggctggat ttcatcaagt catcgtgctt gccaacagct agcaactcac ctttttccaa
     5881 gaggagaatc tggtccgcca tctgtaaagt tgaggttcgt tgagagatca aaattaagct
     5941 cgtgtttgga aaattttctc taatagcttt caagagcttg gactctgtaa tggtatccag
     6001 tgccgaggtt gcatcatcta ggatgagaaa cggagcctgg cgcaagactg ctcgggcgat
     6061 agacaatctt tgtttttgtc cacctgagaa atttcgcccc cctgcctcaa ctagagcatc
     6121 caagagtcct tccttttcac tgacaaaatc cttagcttgc gcaatctcca aggcctgcca
     6181 gagttcctgg tcagatactt cttgattgaa acctagagtc aagttggaac gaatagttcc
     6241 cttaaagagt tcgacctttt gtggcacata ggcaatccaa gatctccatt gctccaaatt
     6301 aagaggactc aatccatcta gataaaggtc aattcttccc ttgtttactg gataaagtcc
     6361 aagtatgagt tgaatcaagc ttgatttacc agaaccagtt cccccgatga tacctagaat
     6421 ttgtccttga gtcatatcaa aggaaatgtc tctcagagaa ggctgggccg catcaggata
     6481 ggtaaaggtc aattcttgga cttgtaaaac cttatctctg gtagcttgct tttgttctaa
     6541 ctctgaatgg atatcctctg gagcctcaac aaagacttcc tcgattcgct tggctgagat
     6601 ataggactgg ttgagggaat tgatcaacat ggctagcttg accaattcca ccaaaatctg
     6661 taagaggtaa ttgataagag caatgagagc accttgactg agcactcctc cttgaattga
     6721 aatatagcct tgccagataa taacgagaag agttccattg acaatcagat aggtcagagg
     6781 tgttaataaa ctagaccaga aacctgtctt ttcttgtaat ctagcataaa cttggttaag
     6841 ggtttgaaaa atctgtaact ctcgtttttc ttgaccaaaa gcacgaataa cccgcatccc
     6901 ttgcaattgc tggcgcgttt cctgaaccag ttggtccgtt ttctttctga gactactgta
     6961 gagaggattg accaatcgag ataaccctac aattacaatg gtcaaaatgg caaccatgac
     7021 taagaaccag aaagtcaact cagctgagat tcgataagcc ataaaaatgg caccaaaaac
     7081 gataatgggc gctcgcaaaa agagacgcag gaattgattg ataccagtct gaatctggta
     7141 ggtatccgaa gtcaagcgag tgaccaaact agaagttgtc agacggtctc tgctgtcctt
     7201 gggcaaggaa agaatatgac gataaagatc gtttgtcaat tccttagcaa agcctactgc
     7261 tgcctttgct gagtaaaatt gagctatcaa ggccactaaa acgccaatta ctgcaaagat
     7321 aaggagcagg ccaatctgca tccagagatg accttgatct ccctgaggta aagattggtc
     7381 aacaatccca gcaatcacca tgggaaccaa gagctcaaaa acagcttcta acagcttgaa
     7441 caagggggct aaaattgatt ccttgatgta gggtttgaag taagataata ggtatttcat
     7501 aaatcccttc tattcatatt ctagaaatga agaaagtggg aagccccact ctctgtttta
     7561 tttgtttaag taaggcaata gatagccata tcctgctttt tccatctcat ccttggccac
     7621 aaagcgtaaa gaagcagaat tgatacagta acggaggccg cctaactccc gcggtccatc
     7681 tgtgaaaaca tgacccaagt gagcactgcc tgaacgagaa cgaacttcaa ttcgctccat
     7741 tccatggctc agatccttgt aataatgaat caactctttg gaaatcggac ggctaaaact
     7801 tggccaacca caacctgaag caaacttatc cttggcaaaa aagagtggct cacctgtcgt
     7861 aatatctaca taaatcccct cttcaaaggt ttggtcatag gcattggtaa atggagcctc
     7921 tgtagcagct tcttgtgtga cacgataaga ctcttcagat agactggcct tcaacacctc
     7981 ttgactaggc ttttcatagt ttgctgcatc aatcaatggc ttatcagcat cggtcacatc
     8041 gatatgacag taacctgaag gattcttcct gagataatct tggtggtagt cttcagccag
     8101 aatgtagtgg cgtaattgct ccacttctac tgcaatcttt cgacccagca tgcgttcctg
     8161 ctcttgtacc actgtgtaga tagctggcaa atctgcttca tcctgataat aaatcccagt
     8221 tcgatattgg cgaccacggt cattcccttg ttgattgata gataaaggat cgataactcg
     8281 gaaataataa agtaaaatct ctctgagtga cacttccttc tcatcgtaaa tcacttggac
     8341 cgtttctgca tggtctgttt ccttgagcaa ctggtaattg gtcgtttcga cttgaccatt
     8401 agcgtagcca acactggttt ctagcactcc agaaatgcgt gaaaaatatt cctctaggcc
     8461 ccaaaaacaa ccacctgcta gataaatttc tgccattttt atttctcctt tatcacgttt
     8521 ttaactaata ctcttcgaaa atctcttcaa accacgtcag cgtcacctta ccgtaggtat
     8581 ggttactgac ttcgtcagtt ctatctgcaa cctcaaaaca gtgtcttgag ctgacgtcgt
     8641 cagttctatc cacaacctca aaacactgtt ttgagctgac gtcgtcagtc ttatctacaa
     8701 cctcaaagca gtgctttgag caacctgcgg ctagcttcct agtttgctct ttgattttca
     8761 ttgagtataa acttcttttc acaaaaagga tatgaacccc tctggtcaag agtttcccca
     8821 tcctatattc tattctttat tttgcttcta cacggacacc ttgggtatca actctcaagt
     8881 catgcagttt tcctttgaaa ggttgctttt ccaattctgc cttaattatt ggcatcttgt
     8941 catgagaagc cagaaccata actgtcggcc cagcaccaga aaggtaggtt gcataggccc
     9001 cattttcttt ggtcacttgc ttaatcatcg caaattctct taccaagtcc tgacgatagc
     9061 gctcatggaa gaggtctccc tcgattgctt gcccagcggt caccatgtct cctgccaaca
     9121 aggcagcaac cgctacattg gcgatagaac ttgcagcaac agcttcctta taagacaatt
     9181 ttttaggcaa gacactacgg ctgtcgcgag tacgtaattc atagtttgga atgtaagcta
     9241 gaaaatcaca ctctggaaag tctgctacga tagcagagac ttgcccttca acagaacttg
     9301 caataacgag attaccataa atggctggag ccacattgtc aggatgccct tcaatcttgg
     9361 tcgctaactg caatttttca tggtctgata agttgagttg acccagttgg ttggctagtt
     9421 caatcccagc aacgataacc gagctggaag aacccaaacc gcgcgccaaa gggacatcac
     9481 tggtcatttt caagcgtctt ggttgcaagt ctggtacaat ttgcaaagcg attttgagca
     9541 agagattacg ctcatcatgt ggaatccatt tgccaatctg gtgttcaatc agccactcat
     9601 ctcgttcttc gcagacctca atttgaagat acttggttac agctacaccg accgagtcaa
     9661 aacctggccc gatattggca ctggttgcag gtacaataat cttcatctta ttctcctagc
     9721 accttgaagg tattcaagag gtcgaattct gaaaccttct tcaattcagc tgagacattt
     9781 tcaagctggg ctttattaat cttgtgtgtg atgataacga cacgcgcctt gtcaccctct
     9841 ttgccatctt gaaggatttg cttaaaggaa atatcttgag cattgaagat ttcagccaac
     9901 ttcaagacct gaccttttga gtctagagcc aagattgaga aatagtagtt tgctttgaca
     9961 tcttcaggat ttgccaagac caagtcacgg ctatattcgt tgaagtcttt gccaatagta
    10021 ccatcattca aacgacgaac gatacggaca atatcagcta caacacttgt tgcagttggt
    10081 ttttgacccg cacctggtcc gtagtacata gactcaccaa taccgataga ttctacaaag
    10141 acagcgttca ttacgccatt cacactagca agtgggtgcg ctttaggtag gaaggttgga
    10201 gtcacttctg cagcaatacc tgaagaagtt tcctcaatag aaccaaccaa tttcactacg
    10261 taaccaagct cttgagctac agctacgtct tctggtgtga tattgcggat tcccttgtgg
    10321 gctacatcat caaaggcaat cttcatgcca aaggcaaatt gactcaaaat aaccatcttg
    10381 taggctgcat caatcccatc tacgtcattc gtcggatcgc tttctgcaaa tcctagacgt
    10441 tgtgcttccg caagagcatc atcgtaagac cagccttctt ccaccatctt ggtcaccatg
    10501 aagttggaag ttccgttgac tactccaagc acgcgcgtaa ttttatcaga agccaaggaa
    10561 tttgctaaag tacgaagaat tggaatccca ccagcaactg ctgcttcgta gtaaagtgct
    10621 accttgttag cttgagcgat ttctagcaat tctgcgccat ggacagctaa aaggtccttg
    10681 ttagcagtaa caacgtgttt tccagcttcc aaggcacgag tgataaaggt tttagcaggc
    10741 tcaatacgcc ccatcaattc cactacgata gtaatatcat ggtctgataa aatatcatcc
    10801 acattggtta caaagttaaa gtcattccct gctgcaagca agcgattttt ttcatcttca
    10861 tccttgacca ataccttagc aactttgata tctgaatgtg ctgattgatt gatttttcct
    10921 ccattttcct ttaggaggaa aggcacacca cttgcaacgg taccaaatcc tagtaaagca
    10981 attttaactg tcatctttat ctcctcgaaa ttttctaata tagccattat aacagaattt
    11041 tgtgaaaatt cctattatag taaatcacta tttcagtata aaaagaaaaa acgaatcaga
    11101 cgattcgctc ttcttaaaat ctgaaaatag ctttccagaa aggattagcc gattttttgc
    11161 agattgagca ctgcatcgtg actcatcaag acttgaccat actcttgtaa gactgagcga
    11221 ctgatatcac tatcgtctgc aaactcgcgc atacgggcca acagccaagc tggatatggg
    11281 cttggatgat tttcaatatc cactaaaatg gtcaaataat agcgctcgtt cattttgtag
    11341 agttcagaag tttccatttc aaaagtcact gtcttggcaa aagctaccaa gtcagccaac
    11401 ttagcaaaag aaaggatgta gtagatgtaa ggttctttct tactctcagc ttcttgttca
    11461 gcctgctctt gctcttcttc cttggcttca acttgctcaa gagattgaat ggcttcgata
    11521 tcatccttgg ttttgtctgc gatgcttttt tccagggttt tgataaattc atctggagac
    11581 atttgagcca attcttccat atctggcaaa tccgataagt cttcaaaatc tagattttgg
    11641 tcaatctttg acttggtcac aaagacatct accttatcag gttttggagt cacacggaag
    11701 ctcaacatgc ctgtatccag aaagctatca ggcatctcta gctcatccaa gatagcataa
    11761 aagaactctt ctgttttttc ttgaggaacg agaaagtcag caatctccat tccacgatcc
    11821 atcaaatcct ctaaagacat cgtgattttt aaagttgtat cactaatttg tttcattttc
    11881 attgctagta acctcatact ttcagttcta tctattatac tagattttta cgattttatc
    11941 aaaagaaggc tcctctatac ggatagattt tccctagggt ctttctatag gagactccaa
    12001 gagaaaattt ctgcagacag atagaaaaag ccttcaaaat cggctcttag ccgactttga
    12061 agaccctata catcagaata cttataattt aaaggttgct acaccgagga tagaacgatt
    12121 taagtttctg agaatttgaa gactttgctc aaatttctta taacgagtca ctccgtactc
    12181 ttcaacaaga aggactgtat ctctttccaa aagagatgat acatcctgta aatctacaaa
    12241 atgcattcct tttaaagctt cttgactctg tttcaattta tctaggatag ctttatttga
    12301 gctaacgatg gtcaattcct gtccagtatt tttgtatgac aaaacatctg ctaggttagc
    12361 aattgttgta atctctgtta caaaatcaat ttgatactga gaaaaatcac ctactctatt
    12421 gattgttgga ttaaagagat aaactaacac atttcccatc acaaccaaaa tcacacaaac
    12481 cactccaata acaactaaac gaagaatcag atttttcaca tttaagccaa gcgctgtttc
    12541 accatttgcg ttcaattctt tagagttgat ggtttccagt ttttcaattt tcacatttgc
    12601 ataagcatgt ttaaatttct caatcaaccc atcaattttt ttctctaaca agtcattggc
    12661 atctttactt gatgtcaaaa ttttcacacc aacccctgca tcgtcaatca tatagtagac
    12721 ggtcaatttt ttccaccaat agtcattcgt tgaatttttc aaggttgttt ctgtcgtgtc
    12781 taattcactg gcaatttttt tcaactcact gggttctaca tcattgaaaa gataagctcc
    12841 attcaaatta ccatcaatca atttcccata aaaatcacta taaccaccaa tttgatgatt
    12901 caaaatcgtt ttggccgaat cttctggagg agtgatttta tagataagat aagttgaata
    12961 acttgttgta tctttgacag tgtttttatt cctaactgct ttaattgtaa atggtacagc
    13021 aatgagagca aataaagcga tgagagctaa aatatttgct tttcgctttt tataaagatt
    13081 tgcaaacaaa tcagctactg aataatgttc aaacatgatt tttttctcct ttgtttagta
    13141 gatactagtt ttcctttgta agcatttttg ctacaaatat aatcacaaga acaattcccc
    13201 agaattgcat tgtaaataaa ttgaagaaac tttctgaaaa gctgcttctt ggcataaaga
    13261 atagattatt caagatgagt agggataaag caaataggat tgtccttgag cgataggcta
    13321 cttgcagcat ggctataaat aatacgccga gtaagaaact aagcagaaag actccaatca
    13381 taccatagtc ggtatacaac tccatgatat aactacttcc gataccatgc cctttcaagt
    13441 attccttgtt caagacaaga taggatagat tgtgggcata actattacta tcaatagcta
    13501 gttccacact attggttgta tgttcaaagg cttttcctcc gaaaatggct cccaaactcc
    13561 cccttgcaaa ataatcaaga acaggaccaa aagtaaaatt acggaaatct cggtaaggga
    13621 ggctactgtt aaatagaaaa cctcgagcca gaacaccaaa actagtccct tgtttataga
    13681 taaagtcaag taagatatcc cagaaacctg tatgggaaac ttggacatta tcccgtacat
    13741 aattgagtac tcccatcgct aacatgagaa taggagaacc tacaaaaatc gctaactttt
    13801 ctttaaaccc aatccatttt cctttttcag tttgctcccg cataaagtaa taaacaaaag
    13861 caaataaaat acttaaaata aagggatttc gtgtcccaat tgccaaatga atagtattag
    13921 ctgcaataaa ggagacaagc actgctgtgg cctgcaattt ctttggcttg gttgccagat
    13981 acatacacat tgcatagacc gtaaaggtag acaaaatgta ggtaaaataa ggcagtttac
    14041 tttcaaaatt tgcatagtag gcatagtagg aagtctgcaa acgatacaag agccgttcaa
    14101 ataaccgaat gaaatagaaa ggataggtta gaagaaaaac tactagtgat acaaagcgta
    14161 accgcttgat ataaacctct tttagagaat ttcctatatt tgctactttt attttcttcc
    14221 tagctatgaa gtaacgagcc agaatgcctc ctgtggtcaa gcccagaatc gaaaccatga
    14281 caactataaa ggcaaaacga taggctattg gatgataggt atccaaagca ccatccctaa
    14341 aataatcaat ggtcggtctt gataccagaa atacaaaaat ggttaaatag aaaataaaat
    14401 ggattaagta atacttgata tcattccaac aagcaattaa gctactaacc aacaagaaca
    14461 ataaagtaga aagtaagcta acattattat tattaaacag atacacaatt ccacttacta
    14521 gcgtcaaggc ataactgact atggtcaaac taaataataa tcgtttccca tcaatcactt
    14581 ggtcaccccc gttctaatgt aattttttag atttttcaat atttttcagt aataagaatc
    14641 gatataagga aatatttatg aatagggcca aagcactaat tcttctcccc ttacggaaaa
    14701 ttggattcct agaaatagca aaggcatggc cttttaaaaa acgatgaatc tgagaatagg
    14761 cttcaaactg tttatactga tcatctagca acatcttatc cagaataaag aagtgggcat
    14821 aggccaatct gaaaaaagcg acctctttca agtcaggata gtttttcaca acttcattat
    14881 aaaacttttg gtagatatca atataggcta aatccttctc tgcatagggt ttggtcgtaa
    14941 tactatcccc tctatggaaa tagtaataat agggtttagt attaaccaca tacttcttgg
    15001 ccaacttgat taaatcaaaa tggtaatagg catcttcgta aatcaacccc ttaggaaagg
    15061 atagggcagt tgcaatctgt ctcttgatta gcttattgca aatcgtccca ggtatttttt
    15121 cacctatgag gtattccttt agaaatgttt gagaatcaca gacaaaatag tcatcctgat
    15181 tggctgactg tgggctttca tcattagcat agacattcat gacaccacag cttgaaacat
    15241 ccgcatcttc ttgaactaat tgctcatata agctctgaat catttctgga tggatataat
    15301 catctgagtc aataaaaatc agataatccc cgtgagcctg cttcatccca tcatttcgtg
    15361 cttgcgacaa tccttcgttc tttttatgaa gcactgacac cctgtcatct tgttcagcga
    15421 ttgaatcaca caagcgacca ctttcatctg ttgcaccatc atcaacaaga ataatttcca
    15481 gattttgata ggtctgcttc tgaatggaag ctatcgattt ttctaggtac tgcgccacat
    15541 tatagactgg cacaatcaca ctaattaatg cagtttccat gctactcctc taatagtttt
    15601 tctacttgtt cgatttgttt tgtaattgta aattgttgaa tgaattggct agcctcatcg
    15661 acatcaaagt ttgaggcaga agtcatgtaa ttagtaatcg cctgagctgc ctcttgattg
    15721 ctctcaatga tttgtccaaa tcgtccttct tgggataatt cctcagcccc tccaacgtcc
    15781 gtagagataa aagggagtcc cagactcaag gcctccacat acactccagg aaaaccttct
    15841 tgtttagaca tagacaagag aactttcgtc tgagatagat actgataagg atttttttga
    15901 taaccaagga aatgtacata gtcctcaatc ccatactctt tgactcgttt tttcagttcc
    15961 tcttccatat caccagcccc gataaaatag agatgatagt tttttccctc ttggtgtaat
    16021 aatcgtatca cttccactac acggtcagaa cccttatttt cctcaatccg tccgatagta
    16081 cagatacttt gaggagcaat ctcgatatcg atcttctctt gagatttttc tagaatagtc
    16141 tgaaaatcat atccattgta gattgtctgt aatttagaag cataatctgg ataaacttcc
    16201 ttgatagaat tcctggtctt ttttgaaatc cctacaattg tattcgcagc atccaactgg
    16261 cttctatgtg attctctttt agagctatcc ttaagaagtt cttcaatact tccatgaatc
    16321 caagatatct tcttgacttc tcttctttta gagaacaaca gtggtggatt cataatggta
    16381 aaagaaactt caacatcata atcatctttt acaagcaaac gacgagtcag tcttggaaaa
    16441 taaattctca ttctccacaa aaaagctcgt aaccatctgg tttggcgata atcttgaagg
    16501 gattttaaaa tgcgtacatg ctttggaaca gattcatatc ccttgtcaaa gtgctccatt
    16561 tcaagaatat caatatcata cttttctgga tccagatttg aaacaatggt tgatagaatc
    16621 ttctctgcac cacctccaag agaaaaagac cacataaaaa ataagatttt tttcttagcc
    16681 accatattct cccttgtatt ttgtataaga cttatccata tcagcaatga cagtatcatg
    16741 atgcggtacc tgcttgtctg ctggtggagg cgtcatataa tccccaaaag cagttctgag
    16801 atagacatca tagccgattg gaataggcat ctctgttcct tcaaatggca agaaaagatt
    16861 gtcttcaaaa gatgtgattg ggtacttgtt tctcatgtag ccaggacctg agcataattc
    16921 tgtaatgcca tcacaatcag ccaaatcata cttagtcatt tctttctcag cttttttcca
    16981 gatgcgataa cggagagatt ttggagtcaa acccagtaaa atgcgacttc cccatttcat
    17041 gagagcacca tgcttttctg gaatagtttg cgcacaaaag agtgaataaa tcaaggccca
    17101 acgaacctgt tttttccgct cagctggatt tttcggataa taatccaaag gcaaaatatc
    17161 caaggccaga ccatgtggca aatccaaatc ctgctgataa ggcttgatac aggtggtttc
    17221 cttgtcacga atggtaataa aaagattacg atcaacaaaa ttcttatgac tctttgacaa
    17281 gaaataacgt tcatctgcat aacgaggcca taattctgct aatttctcat aatctttacg
    17341 aggcataaaa aagtctaggt cgtcgtccca aggaataaat cccttgtttc gaagggcacc
    17401 aatagcgcct ccgccacaga gataacagag caaatcatgt tctttacaaa aggccacaaa
    17461 atattcagcc atctccagac tacgagcctg aattgctttt aaatcagtca tattgttcat
    17521 tattctttct atcgtatcgt ttcattatac cacaaacaag gggtgaaaat ctattgcaga
    17581 ctgtaaaaaa tcaaagcctg actgctatcc aaatagctat caaactttga tttttctgtc
    17641 ttatactctt cgaaaatctc ttcaaaccac gtcagcttca ccttgccgta ggtataggta
    17701 actgacttcg tcagtcttat ctacaacctc aaaactgtgt ttttagcagc ctgcggctag
    17761 cttcctagtt tgcactttaa ttttcattga gtattatctt atctcaagcc catttgagcg
    17821 agcttggttt gatatttgtt ttgatcaacc agcaagccca agcctccata aacatcatag
    17881 gcatctaccc agtcacccag ttctggaatc gtcaattttt caataccatt ttttgctcca
    17941 tccaaaacag ataaaccgtt tgttaggagg aaagtatagg ggacgttggt tgaggtcata
    18001 gcaaaaacct ttccaagagc ttcagaacca gtgaaaagtt tagtgggatc tttaatttgc
    18061 tctaaaattg ctgttaaaac ttgttgctgt ctttttgtac ggccgtaatc cgcctcatca
    18121 tcatcacgga aacgagcata attgagcagg gtcgagccat tcatctgctg ttttccgact
    18181 ttaatggttt gggttggaga ctcagtctcg gtagcgtata aatcatctcc gactgtagct
    18241 tctgttaggg gacgcccatt caatgttgaa aattgagcat caatcgtcac cccatcaggg
    18301 aaaagcgtgt caatcgctgt ggcaaaggcc tggaaatcaa ccaaggcgta gtacttaatg
    18361 tccaagtcaa aattatcttt caagacttgg cgaaccattt ctgccccttt ttgcccctct
    18421 tgttctccta actcgtaggc tacgtttaac ttgttatctg tctgttttct accgttaatc
    18481 acttgactat aaccatctat atagaccaaa ttatcacgca tgaaactgac tagcttcatt
    18541 ttcttatctg agcccccgac atttaatacc ataatagagt cagttcgtgt ctcaacactg
    18601 ttctggccga ttcgaccatc agtacccatg attaaaatat taactccatc tctagtgtcc
    18661 tgaccattaa agacttctac ttgagctgcc cgggcatcag cagttttctt tgcgctagca
    18721 tcttggtaac cacgcaaaaa catgaatacc atggccaaag ccacacagac caaaagtgaa
    18781 aaaatcacca taaaaattcg tttaagacgg agcttccgtc ttttcttttt tggagggaaa
    18841 gagagtgctt gtgatttgga ttgtgagcga ctccggttcg catagcttgg taagtcaacc
    18901 tgctcttctc tttcttgttc caagctagag ctactatttc ccctagcaag agttagcttt
    18961 tcttgcaaat aggcaaactc atttttttct ctctcattga gatagtgaat attttttagc
    19021 aaataatcat aacgcaactg ctcatgatga cttaagggat tttctttact catcttctct
    19081 cctttccatg gtctgatatt ggataaatag gataggcacc cagaatttta tactggattc
    19141 caatcgcttc taattctttt tgggcaaagt ggaccaagtc cttatcggta taatccacat
    19201 cgataatgaa aaagtattca cccagtgctg tcttgagtgg acgactttca atttttgtca
    19261 agtcaattcc tcgccaagca aaggtcgaca gggccttata aagtgcacct ggaaggttgt
    19321 caggtaatgt caaggccaaa ctcatctttt cagtttgtgc ttgcaaggga atactaggct
    19381 tttcagctcc tagaacccag aaacgtgtta aattggcttc catttcctga atatcctcgg
    19441 caatcagttc caatccatat tcttcagtag aacttctagg tgcaattgct gcaaagggct
    19501 gatctggatg ttcggaaata aaacgggccg cataagctgt actagctgtt acctcgattt
    19561 gagcctctgg atattgttca tcgatgaatt tctttccttg agccaaggcc tgtggatgtg
    19621 aaaaaatctt ttcaatctta gtatggcctg gaaccaccat caactgctga tgaataggct
    19681 gaacgatttc tgctactgct tggatgtgag cctgatgaaa aagatagtcc aaggtttcat
    19741 gaacactacc ctcaatagag ttttcaactg gcaccacaga atagtccact aatccttgct
    19801 cataagcctt gatgacatct gtaatgttgg caaaagcctg caattcctca tgaggaaaag
    19861 ctgtctgcac aacgtggtgt gaaaatgatc ccttgggacc tagataagca attttcatct
    19921 tagttcctct ataatttcct ctgggcttag cttggtcaca tccaaaaccc gactagccac
    19981 ttcctcatac caagcctgtc tttcttgaaa aatagctact agttcttcct tgctattatt
    20041 tagaaaaagc ggtcgctgat tgtccttatc agctgcgata cgtaggtaga gggtttcaaa
    20101 atctgctttc aggtagatgt tatctgtatt agtcttgagt aagtcacgat ttctctgaga
    20161 aataaccact cctcctccag ttgacacgac ttggtctgtt tgtagtaaat cagctaggac
    20221 ttctgattct acatgacgaa aggctgcttc tcccttttca gcgaaaaaat tcgcaatgga
    20281 catacctagg cgcttctcaa tcagagcatc catatcaagg taattagtgt ccaagcctct
    20341 tgcaatagtc gattttccag cccccataaa ccctaataac accttagcca tgaatcaagc
    20401 tctccaaatc atcaaagaaa ctaggatagc tggtattgat ggcttctgca cggtcaagct
    20461 ccacctctcc atctgcaacc aagagggctg cgatagctgt catcatgccg atacggtggt
    20521 caccaaacgt attgactcta gcaccgtgaa gagctgattt tcctttgata atcatcccat
    20581 ctgccgtagg agtaatatct gctcccatac tatttaaggc gtctgccaca acctgaatac
    20641 ggtctgtttc cttgaccttg agctcctcag catccttgat aactgttaca ccttgggctt
    20701 gggtcgcaag tagggcaata ataggcaatt catcaatcaa acgtggaatc aaagcgccac
    20761 aaatctctgt tcctttcaag tcagaagact caacaatcaa ggttgcagat ttagcgactg
    20821 gatcgatttc agttatttcc aattttccac ccatggcacg aatgacatca ataataccgg
    20881 tgcgagtttc gttgatcccc acattctgca gcactagacg agaatttgga acaatcaaac
    20941 ctgcgactaa ccaaaaggct gcactggaaa tatctcctgg tacgaccacc ttctgtcctg
    21001 tcaatttttg tggtccttgg actatgattt tcttaccgtc cacacttaaa tgaccaccaa
    21061 attgtttcaa catatcttca gtatgattac gagtgcactc tttttcgata ataactgacg
    21121 cccccttagc ttgtaaggct gcaaacatca aggctgactt gacttgggca gaggcaattg
    21181 gcaactcata atgaataggt cttaggtttt tcgtcccttt taagcgaagg ggaggcaagt
    21241 ctcgttcagt ttgtcctgaa atgctgacgc ccattttttt cagtggaagg gtcacacggt
    21301 ccataggacg tttggaaaga ctatcatctc caaacatctc tacttcgaaa tctgcaccag
    21361 caaggacacc tgaaatcagg cgaatcgagg tgccagaatt tcccatatta agggcatttt
    21421 gtggcgcttt taagccagcc atgcctacac cttgaatggt aataacccca tctttatcct
    21481 caatttcaac accaaggtca cgaaaaacct gcatggtcga aaggacgtct tcacctcgca
    21541 gaatatcata aaccttggtc tcaccctcag ccaaacttcc aaagataatg gaacggtggc
    21601 tgatagactt gtcacctggg acgcggatac taccatgtaa atggcgaatg tttgttttta
    21661 gtttcatact ggacctcata cttgcaatac ttttacctat tttatcataa aaagccagaa
    21721 attccttaaa aattcctgac tttaggatcg ttcttttctt atttcagcaa ttctgaaact
    21781 ggttcaaaaa caattttttc aatgtcagaa aggtaaatgg ccaattgttg ttgcttggta
    21841 aagaattctg acaagaggct atttccttga atctgtttac caaagccttc catcttagct
    21901 tggaaggacg catctggcat ttgacctgta tgtgctagtt tttgaatttc ctcttgaaag
    21961 gcaagatatt ctgtaaagat tttgcttgcc tcagcatctg ctgcaatcgc atctttagct
    22021 gctttaacag ccttgtattc tggtaatccg cgtagaccgc gactgagttc gtttgcacta
    22081 tcgtaaatat ttgacatgtt cttctcctta tttgatgacg actgtatagt cggtattttc
    22141 tgttatgaga tgctcagctc tttccaagtc ttgagcattt ttaaatgaaa tttgtaggat
    22201 tccgtgaata tcctcacgat tttcctcgtt gatgtggatg ttaaccaagg aagtcccacg
    22261 tagcagttcc aaaatccgca ggatgacatc ttcttcatca ggaacgtcaa catagaggtc
    22321 gtaagagcta tccacaccac cacgcttatg gatttccatg gtctggcgtt gttcacgcgc
    22381 ttggttaaaa aagttccaaa tttgctcttc atctccctta ctaatggcct gaccaatcac
    22441 ttccaaacgt tccttgaaat cctcaattct atccagaatg gtctcgctat tggacaagag
    22501 aatggaggtc cacattcctg gctcgctttc cgcaattcgg gtcatatctc gaaaaccacc
    22561 tgccgcaaag cgccttgcca tctcatgctc ttgagcatag accgcagtct gctccatgag
    22621 actagaagcc aaaatatgag gaaaatggct aatctgagaa gtgacacgat catgctcctt
    22681 ggcatcaatc tcgataaaac gagcatgaag acctgaaagc agatccttca tttccttaag
    22741 cgtgtcctga cttgtcaggc ttgaaggtgt aaagatataa taggcatttt caaaaagatt
    22801 gacatctgcc gaagcagccc ctgtcttgtg actaccagcc atgggatggg ccccgacaaa
    22861 gcgaacagac ttgccagcca aatactgctc cgccgcatcc acaatggttg acttggtcga
    22921 accagcatct gaaataataa cgccttctcg caaatccaaa ttggccaact ccttaatgaa
    22981 agcaatagtt tgtttgattg gcaagctgag gataatgaca tctgccaaag gagcaaaact
    23041 agcaaaatca tccgttgcac ggtcaatcat gccttctttc aaggcgatat ctctcgaagc
    23101 ttgactacga ttataaccta aaatttcata atctggatga tcgcgtttga taccaagtgc
    23161 catagaggct ccaatcaacc caagacctgc gatatagatt gtttttgcca taggaactcc
    23221 ttaatagttc tttgtatagt ctcggtattt ggctaccgct tcttttagtt cctcaagatt
    23281 atctgatgag aatttttcga ggatttcttg cgccagaacc gttgctacaa ctgcttccat
    23341 gaccattcct gcagctggaa gagcagtcgg atcacttctc tccacggttg ccttgtaagg
    23401 ttcgtgggtt tcgatatcca cactcataag aggtttataa agagtaggaa tgggtttcat
    23461 gaccccacga acaacgatgg gttgcccatt agtcatacca ccttcaaaac cacctagatt
    23521 attggtacgg cgagtataac cgtcttcttt agaccagaga atttcatcca taacttggct
    23581 gcctttacga taaccagcct caaagccaag accaaattcc acccctttaa aggcattgat
    23641 agagacaaca gcttgagcca atcttgcatc caattttcta tcccattgga cataggaacc
    23701 aagaccaact ggaacgcctc cgacgactgt ctccacaacc ccaccgatgg tatcaccatc
    23761 acgtttgatt tggtcaatat agtccttgat ttcctgttct cgttcttggt taacaataga
    23821 aacttcagac tgggcagctc tttgcttaat ttcagcgact gtcagatttt caggaacatc
    23881 gatttccttg ccaccaaaga ccacgacatg gttggcaatc tccatatcca gctcagccaa
    23941 gaggcgtttg gctactgcac caactgccac ccgcatggtg gtttcacgag ctgatgaacg
    24001 ctccaaagaa tttcgcaaat catcaaaacg gtacttgatg cccccaacca aatcggcatg
    24061 tcctgggcga ggatgggtga tttttcgttt gcttttaagg cggtcttcaa tgtcctctgc
    24121 agacatgata tccagccatt tttggtggtc cttattgacg acatccatgg taataggagc
    24181 ccctgtcgtc ttcccatggc gaacacctga agtaaagaca acttggtcgc tctcaatctt
    24241 catacgaccg ccacgaccgt agccaccctg acggcgttta aggtcgccat tgatatcctc
    24301 agctgtcaaa ggtagtccag ctggaattcc ttcaatgata gctgtcagac ggggaccgtg
    24361 tgattctcct gcagttaaat atctcataca ctctccttat tttaccaagt agtctttcat
    24421 ctcttccaga gaaactgggt gaatggtcgc tgaaccaagc tctggtacca agaccaattt
    24481 caaggtattg ccacgcgctt ttttgtcatg agtcaaagcc tgataaagct tgtcaacatc
    24541 ccagttttca tagtcaacag gcaagccaaa tttctgacac atatctgtaa tggactgagt
    24601 tatgccagct ggcatgaggc cttttttctc agcaaccttg gaaatctgca ccatgcccat
    24661 ggccacagcc tcaccatgca tgaccttacc ataaccggca gttgcttcaa tagcatgacc
    24721 aatagtgtga ccaaagttga ggtaaaggcg tacaccattg tccaactcat cctcaaccac
    24781 catcttgcgc ttaacctgac aagaatgttc aatcaaggtc tctgcatgtt ccagaatgct
    24841 ctcaacagaa ccatccagct ccgtcaaaag agcccacagt tctggatcct caatcaagcc
    24901 atacttgata acctcaccca tcccttcaat caactctctt tttccaagcg tttcaagaac
    24961 aagtgggtca atcaaaaccc catctggttg ggcaaaagtt cctaccatat tcttggcaaa
    25021 tggagtgtta acacccgtct ttccaccaat agaagaatcc acctgggctg ttaagctagt
    25081 cggtatctga acaaaatgaa tgccccgcat ataggtagag gctacaaaac cagccaagtc
    25141 cccaacgaca ccaccaccga gagccacgat tccatcgcta cgagtcaacc cctgcttaac
    25201 taggaattca tagactttct gaacagtggt taaattcttt ctttcttccc cttctaaaaa
    25261 gtcaaaaaca gctacctgaa aaccagcatc ttctaggctg agcttgacct tctctgcata
    25321 aagagaagct acatggttat ctgtcacaat gactaccttt tgtggttgcc agagttctcg
    25381 caaccattga ccagcctgag ccagacaacc tttttcaatc tgaatatcat aaggatgatg
    25441 aggaatatcg attctgattt tcataggaga atctcctttt ctttattggt atttttctgt
    25501 taaagactgc caaatctctt ctgttggcat ttccttgcct gtccacagtt gaaaagcttc
    25561 tgcagcttga tagagcaaca ttcccagacc attaaccgct ggtttgccct gacttctggc
    25621 ccattttaaa aatggcgttt caaagggttg ataaataata tctgccacca agatagtttc
    25681 tggcaaattg atgctttcag gaactgggga tgattgacca tccatgccca cactggtggc
    25741 attgaccagt aaatccgact cgacaatcct tgcttgcagt tcagaaacat tttctaaagc
    25801 atacaagtcc actttaaagc ctgtttgctc ctgtaacttg tctaggtaag gtcttgtttt
    25861 ttccatagaa actgaacgaa caaagaccga aatctgactg acgccatcca aaatagcctg
    25921 tgccaagatt gatttagccg caccacctgc acccagcagg gtcatctttt tacctgaaat
    25981 tgtaaaagaa ggcaagcact taaaaaatcc cttgccatct gtattatatc caattaaatt
    26041 gccattctca ttgacaaccg tattaaccgc accaatcaag cgcgcttcat cgctcagctt
    26101 atccaaataa ggaatcacct gctccttata gggcatggac agattgatgc caaacatctg
    26161 gtagcgacga atattggcca ctgtttctgc caagtcactc gcttcaatct cccaagccac
    26221 ataagcaccg ttggtagctg tcgcctcaaa ggctctattg tggatgaagg gagaaataga
    26281 atgcttaata ggattggcaa caactgcagc taaacgtgta tagccatcaa gcttcatcca
    26341 aaatctccct gatttttttc atgctagcta gagaaatctg cccaggggca ctaacctcat
    26401 ccagactggc aaaagaccaa ctcgaaccag tcacatccgc agtgatacga gagaccttgc
    26461 ccaccttacc catagaaatg gtcacatatt cctgttcagg attgagggtt ttaaagcctc
    26521 gtgtatagtt catcaagtct aagacatcct gctccgtgtg agccatcacc gcaaccttaa
    26581 caagttttgg atttaggatc gtcaactctg acaagatttc catcatgttc tcaggtgttt
    26641 cttggaaatt atggtaactc aaaacaagat ttgggaagtc cagcatttcc tcaaaaacat
    26701 ccttgtagct atagtactca aaatcaatat agtctggttg atagaattgc gcaacttcct
    26761 tgattagatg gatatactct tctggagaaa ggtcgatttc tccaccttcg gagcgagttc
    26821 gtagcgtgaa aaccaactca cggcctgcga atttttcaaa aatggctgga gctacctgca
    26881 aaatcgcttc tttaggcaga tagtcggcac gccattcaat gatgtcggca tccaggtacc
    26941 tcgtggcacc cagagcctga gcctcctcta aacttcttgg cattactgaa acgattaatt
    27001 tcatttacta accttcatac taatcacctt gaggtaatta ctactttcat cttttttatt
    27061 ataggcaaaa tctgctggaa gaccatattt gtttaaaatc tggtaacttc ttcctgcaaa
    27121 gcctttatca atttgttctg taaatttctg acgggaaaca ttggcagcat tggtactggc
    27181 aatgataatc cctcccggat ttaaaatctc aagactctgg gaaatcaact tgtgataatc
    27241 cttggccaca gagaaagttt gttttttatt ccgagcaaag ctaggcggat ctaggacaat
    27301 cacatcgtag gtcaagtctt tgcgtttggc atatttgaaa tactcaaaga catccatgac
    27361 tataaaacga tgctcgtctg tgctgagccc atttgcctga aaatgcgctt gagacaattc
    27421 tcgtgaacgt ttggctagat caacagaagt tgtctggcta gctcctccca tggccgcagc
    27481 tactgaaaaa gccgctgtgt aggaaaacat attgagcaag gatttaccca tagccaagcc
    27541 gtcaactaaa ctaccgcgaa cctcatgctg gtctaggaaa attcctgtca tcaagccatc
    27601 attcataaag acttgataca ggacaccatt ttctaaaaca gtgaaaaagt caggtgcttc
    27661 ttgaccataa acatgggcag attcatagtc aaaaccctta aagcggattt tctcataagc
    27721 ccctaaaacc tcagggaaaa cctgtctaaa ggcttctgat atagtctgac gaatctgata
    27781 aacataagag ttataccaag aaaagacggc gtagtcgcca taaaggtcca ctgtcagacc
    27841 cccaaagcca tctccctctt gattaaagag acgaaaggca gttgtcaaat catcttgata
    27901 gtaggcgttt ctcttttctt tggcttttct aaacaacgtt tcaaagaaag tttgattgaa
    27961 ggccaccttg tctttgctga caaaccagcc caagcccttg ttttgctgag aaaggtaggc
    28021 agtcccaaga aagtttcctt cctgaccctg cacctctact tcctgatcct taagattgac
    28081 attctcaaga tcactggctt ctagtaaaac tagcccctta gcaagcttct tttcaaccct
    28141 tttgctgact cttattctat tcataactac cattatatca aacttttaga caattctcaa
    28201 aaaagaaact acccttgctt ttttactctt cttttaaaaa atggtatact agacttcctg
    28261 caaaactagg aaataaatgt gtaagaatca caataaaaaa tgctcttccg tcttggagga
    28321 gcatttcttt ttatcaacga aaatcaaata gcaaactatg aaactagcct caggttaacc
    28381 gtgagattat aggtagagag gttgtatcag caatatgtgt ctgtcaaatt tagtgacaaa
    28441 ggtagtagaa gaaagatgaa gaaataaatc agcttcagta ggtatctgga aaatttgatt
    28501 ttatagagaa gccttttgtt acaaactcaa tatactatca ataaataata ttatagaagc
    28561 aacaataatt aaaatttcac ctatttgcat cattctattt cgaactctaa atatatgttc
    28621 tatcaaaaat acttggatca cacacattat aggaattaac gtttttgaaa ttgaaaaata
    28681 tcccaataaa taaactataa acaacaataa tagaactata ttatatttct tattcaaaac
    28741 attcctccct atatttttga ttaccaatct taatcattta caactacatt ctaacaaact
    28801 ataaaagcgt ttgtcgaatt gaatttatca agcaagcaac caactatctc atcttttttc
    28861 tatttctgcc aatatgcgtg acaggtaata atgatagcca aaaatagcaa gagcaagcaa
    28921 gacgataaga gctcctactc ccaagttgat ggcaaggata ggggagagag actgaaccaa
    28981 gaatatgctc ccaattacaa gggccatcag gattgcacta taaataaaca ataaaactat
    29041 ggcgactatg ccatttgaac gattcaccag gtccgtaatg ctactccaat tggttgacag
    29101 atttttaacg tccttaaagt aatggtggca agaaaggatg acactggcaa tgatccagac
    29161 tacaagaagg taaatcatcg aaaggatgga caagcctaga tatagagaaa gaccgagcaa
    29221 agtcagaact ggtaaaaagg actgaacagc aaagataatc caaaatttca ctttcacata
    29281 acgagcaaag tcaaagggta aactcttcag aaaatcaaca ttttccctct ccaaggacaa
    29341 ggcaattgaa tgcaggctgg tgatattgtt attgacaact gctataaaca ctcctacaaa
    29401 aaacaagggt aaccagtatg gaggatgaat gtctggaact atctgagaat ctcggatttt
    29461 ggaaatcaga ctgatcatca tgagataagg aaggaaagca cttgtaaaaa gcactgtaat
    29521 cacaccagtc ccctgtccca agagggtgag gtggtagcgt aaaaccatac ggaaaaagcc
    29581 ctttttagta gttgaaatcc tctccttgct gcgacgttct tttttgacct tctcctcact
    29641 gttaagcagg atcacgtcat aaaaacgagg aaggaccttc tttttggtca gataaagcag
    29701 gaagagagtt agtcctatcc aagcgagcag acccactaag gcttctgtcg aaaaaggctc
    29761 cactgctatt ttgtaaaaga tatgaagagg ataaaggaga aatggaatgt ctctaacttt
    29821 gtcaacaata cttccaaaag tcgactgaag aaagaagata aatattaaag gtatgagaac
    29881 tcctatccca atcatcacat tcgaaaaaat agactgatac tttctgaaga ccctagtctg
    29941 agccaagaaa tgtactgcca ctaccgtcac taaagtaaca gagacaaata ataaggtcaa
    30001 ggacagtagc atcaaaggca aacccagcca aagagaagga gctagactaa tatagagggc
    30061 tagaaaataa gctaggattg gtacaattcc agttagagct ggcaagagga cagacagacc
    30121 tttggccatt ataatctctg attctttaaa ggcatagggc ctataggagg ccaggtcctt
    30181 actctcataa aagacattgt aaaaggcagt gaaagaagtt gaaaaggcca gcaccagtaa
    30241 aatagcaacc atcgagctaa aataaatagg catttcctca aaaggaaaat gaatggctat
    30301 attactaaaa cagatgagca tcaagagact ggaaaaaatg taagaactta ggactctagc
    30361 agaaacattt acttttttcc caggattctt agcctgcttc tttcgtagat tagccagatt
    30421 agcttcttga gatgaataga ggatattgat atcaactaat tttttaatga ccttgagacg
    30481 catccgcaac ctcctctttt ctaccagcaa gactaaggta gatactttcc aaaaactggt
    30541 ctgggtggtc tttcctcaag ttctctacac taccacaata gatcaaatgc ccctttttca
    30601 aaatagcaat ccgatcacag acttgctcgg ctacctcaag gacatgagtt gaaaacaaga
    30661 ccgtcttgcc tttttgtgca tgttccttca tcatttgctt caaatcaaag gcggcctggg
    30721 gatccaaacc agtcaagggt tcgtccaaaa cccaaatatc aggagcagac aagagtgccc
    30781 caatgacaaa gactttctga cgcattccgt gagaaagagt ttcaataacc tgatagcggt
    30841 tttcagcaaa atcaaaaacg ttcaatagcc tagctagact agtctccaag tcagagctag
    30901 tcagatcata ggatgaagcg atcaattccc aaaattcatt ggccgttaag cgtaaaaata
    30961 agtcaggcga gtctgctacg tagccaatct ttcgtttgat cgccaagcga ttttccgata
    31021 actcctgacc gtctaccaaa atacgaccac tgctgggtga aatgatactg actagggatt
    31081 ttatggtggt cgattttcca gccccattat gaccaatcaa gcccataatc tctccatttt
    31141 caatctgcaa attgagatta ctcaaggcct ctttatcacc atacaactta ctaacatttt
    31201 gaaattcaat catgggacaa ctcctatctt tatctgtatt atacatcgct atactagcac
    31261 tttgatacaa aaaaatcaat actttatttt aagtagttaa aatagtttcc ttctatctta
    31321 cgcaaacgtt tgcgccgaga gatactttat gatagaataa agaacaagat tgacaagtaa
    31381 gaggaaacat catgcaaaat caaacactca tgcaatactt tgaatggtat ctgccccacg
    31441 acggtcaaca ctggacgcgt ctggctgaaa atgctccaca cctagctcat ctggggatca
    31501 gtcacgtctg gatgccacca gccttcaagg caaccaacga aaaagatgtc ggctatgggg
    31561 tctatgactt atttgactta ggagagttca accaaaaagg gactgtccgc accaagtatg
    31621 gtttcaaaga agactatctt caagccattc aagcccttaa agcacaggga attcaaccta
    31681 tggccgatgt agttctcaac cacaaggctg ctgccgatca cagggaagcc tttcaggtca
    31741 tcgaagttga tcctgtagac cgtacagttg aacttggaga acccttcacc atcaatggct
    31801 ggactagttt taccttcgat ggtcgccaag atacctataa tggcttccac tggcattggt
    31861 accacttcac tggtacagac tacgatgcca aacgcagtaa atctgggatt tatctgatcc
    31921 aaggggacaa caagggctgg gctaacgagg aattggtcga taacgaaaac ggaaactacg
    31981 actacctcat gtatgccgac ctagacttta aacatcctga agtcatccaa aacatctatg
    32041 actgggctga ttggttcatg gaaacgactg gtgtagctgg tttccgtttg gatgccgtta
    32101 agcatattga ctctttcttt atgcgcaact tcatccgcga tatgaaggaa aaatacggtg
    32161 acgatttcta tgtttttggt gaattttgga acccagacaa ggaagccaat ctggactatc
    32221 tcgaaaaaac ggaagaacac tttgaccttg tcgatgttcg tctccaccag aatctctttg
    32281 aagccagtca agctggcgca aactatgacc ttcgtggcat tttcacagat agcctggttg
    32341 aactcaagcc tgacaaggct gtgacttttg tcgacaacca cgatacccaa cgaggacaag
    32401 cccttgagtc taccgttgaa gaatggttca agccagcagc ctatgccctc attttgttac
    32461 gccaagacgg ccttccatgt gtcttttacg gagactacta tgggatttca ggccagtatg
    32521 ctcaagaaga tttcaaagaa atccttgacc gcctcctagc catccgaaaa gatttggcct
    32581 atggagaaca aaatgactac tttgaccatg ctaactgtat cggttgggta cgttcaggtg
    32641 ctgaaaatca atccccaatc gcagtcctta tctcaaatga ccaagaaaac agcaagtcaa
    32701 tgtttgtcgg tcaagaatgg actaatcaaa cctttgtaga tttacttggt aaccaccaag
    32761 gtcaagttac aattgatgag gaaggttatg gacaattccc tgtctcagct agatccgtaa
    32821 gtgtctgggc agtcaatacc atctaatagc tcataataac caagctaggt ccaagcggat
    32881 ttggcttttt tgtattcaca aaaagaccta cccaaatgga tagatcttta cttgattaca
    32941 atttacctgc tactgcatcc aacaattctt ggatcttagc ttggttgctt cctcctgcca
    33001 tggccatgtc tggtttacca ccaccacgtc catcgatgat tggtgctaat tctttgacaa
    33061 ggtttcctgc atgaaggtct tttgtcttgc ttgctacaag gacattgact ttgtcaccga
    33121 tagcggcaac taggacaaga agatcagagt agtctttttg tttccagtta tctgcaaagg
    33181 tacgaagggc acctgcatcg gatacagaca cttgactagc aatgtaacga tgaccgttga
    33241 cttccttaac atctttgaag atatcgcctg cggctgcagc tgcggctttt tctttcaact
    33301 cagcattttc tttttgaagt tgacgaagtt gttcttgaag tccttctacc ttgtgaggta
    33361 cttccttgac ttgaggtgct ttcaaggttg ctgcgatagc tttaagagca tcctcttgtt
    33421 cacgataggc ttcaaaggct tccttaccag tcactgccaa gatacggcga gttcctgaac
    33481 cgattccttc ttctttgaca attttgaaga gaccaatctc agaagtgttg ccaacatgag
    33541 taccaccaca aagttcaata gagtagtcac cgatagtcac gacacgaact tccttgccgt
    33601 atttctcacc aaagagggcc atagctccca tttctttagc agtgtcaata tccgtttcaa
    33661 ctgtcttaac ttcaagagct tcccagattt tttcgttgac ttgctgttca atcgcacgca
    33721 attcttcagc agttacagct tggaagtggg taaagtcaaa gcgaaggaat tcaacttcgt
    33781 taagagatcc tgcctgtgtt gcgtggtttc caaggatatt gtgaagggca gcgtgaagca
    33841 aatgagtcgc agtgtggttt ttcatgacac ggtgacggcg attgctatca attgccaagg
    33901 tatattcttg gttcaaggca agcggtgcaa ggacttcaac tgtatgaagg gcttgaccat
    33961 ttggggcttt ctgaacattg gtcacagtag ccacaacctt acctgactca tccaagattt
    34021 gtccgtggtc agcgacctgt ccacccattt cagcatagaa tggcgtttcc gcaaagataa
    34081 gtgaggtagt tccttctgaa acagcttcta cttctgcatt gtccgccacg atagctacca
    34141 atttagaaga caattggcta gcattgtagt tgaagacact ttctacagtg atgttttgaa
    34201 gagtttcatt ttgcataccc attgagccac ccttgacagc tgaggcacgc gcgcgttctt
    34261 gctgttcttt catggctgct tcaaaacctt cacggtctac agtcatacca gcttcttcag
    34321 cgatttcttc agtcaattca actgggaacc cataagtatc atagagtttg aagacatctg
    34381 aaccagcgat aacagattga cctttttctt tcaagtctgc tacaatgcct tgggcaaagt
    34441 gttgacctga gtgaagggta cgggcaaatg attcttcttc gctcttaacg attttctcaa
    34501 taaagtcacg tttctcaagc acttctgggt agtagctttc catgattttt ccaacagttg
    34561 gaaccaattt gtaaaggaaa ggttcgttga tacccaattt ttgaccatgc atagaagcac
    34621 gacggagaag acgacgaaga acataaccac gaccttcatt tcctggaagg gcaccatcac
    34681 cgatagcaaa tgaaagagaa cgaatgtggt ctgcgataac cttgaagctc atgttgtcgc
    34741 catcttggtc ataaacctta ccagacaatt tctcgacttc acggataatc ggcatgaaga
    34801 ggtccgtttc aaagttggtc ttagcccctt gggtaacggc caccaaacgc tccaaaccag
    34861 cgcccgtatc aatgttctta tgtggcaatt ccttgtattc gctacgagga acagcagggt
    34921 ctgcgttaaa ttgtgacaaa acgatgttcc agatttcaat ataacggtcg ttttcaatat
    34981 cttctgcaag caggcgaaga ccgatatttt ctgggtcaaa ggcttcccca cggtcaaaga
    35041 agatttctgt atctggtcca gaaggtcccg caccgatttc ccagaagttg tcctcaattg
    35101 gaatcaagtg acttggatcc actcccactt caatccagcg gttgtaagaa tctttatcgt
    35161 ctggatagta ggtcatgtaa agtttttcag cagggaaatc aaaccattca gggcttgtca
    35221 aaagctcata agcccaagtg atagcttcgt cacggaagta atccccgata gagaagttcc
    35281 ccaacatttc aaacatggta tggtgacgcg cagtcttccc tacgttttcg atgtcgttgg
    35341 tacggatagc cttttgggca ttggtaatac gtggattctc agggataatg gtcccgtcaa
    35401 agtatttctt gagggttgct accccagagt tgatccacaa aagagttggg tcgtttacag
    35461 gaaccaaact tactgatggt tctactgagt gacctttggt cgcccagaaa tcaagccaca
    35521 tttggcgtac ttgtgcacta gatagttgtt tcatattgtc tccttattta cttgtttaat
    35581 gtgattggct ttccagcatt tccacatagt caatcgcgac acagagggaa atgactaggt
    35641 ctgcataagc gtcctcaaga accgttacgg tataggtaga ggtcagatgg aagagttcct
    35701 tcttaatttc cgcaatcagc tgatcgcgat catccagcaa tttgaaattc aaatcccaga
    35761 tattgccctc gatacgaaga cctagattat caaactcata cttatctcgc cagaaggtca
    35821 acttcttacg aatgacaaaa ctcgagccat cccgaagctg aatctcaaaa cgaggaagca
    35881 aggtcaagat ttctttacta atctcactga cttgttcacc agccgcatca tagatggtaa
    35941 aggttttagg aatcttaaaa aatgatccct ccacctgata ggcaatttct cccctgtcat
    36001 ccttgatagc gaagcgttcg cctccaagac gaaacttttg tttgacaaga aatgttttca
    36061 tcaacacctc caaaaatcaa aagacaagct catatcacga agggcgaaaa accgcggtac
    36121 caccttcatt caatgaactt gtcattctct tgttcttatg caattgtatg attgagtagc
    36181 atgacttcct agcttagatg gctcgcagca ccgccatttc tctggactaa gacaagtgaa
    36241 aatcaattct caactttctt attataacgt ttttttaagc ttgcgtcaac tggaaatgat
    36301 ctccgttgaa ttagaccaat tccctacatc tctgattact ttttcaggat atattttttc
    36361 ttactgccgt ttttcttttt atcccaaatt ttcatattac taaacacagc tactagaata
    36421 tttccaaata taaaggtgcc tatcacccaa tatatggact cagttgttag gtattgtcga
    36481 tccaagccat cctttaaatg ggatagtata acagtttggt taacaatcat aaaggttggc
    36541 cagaaacttt ttttgaaaaa agtagacatt ttcattattt gttgccgctt tctgtaaggt
    36601 taatactcaa taaaaatcaa aaagcaaact aggaagctag cctcaagctg tacttgagta
    36661 cggcaaggca acgctgacgt ggtttgaaga atataggctt agtatactac taggcaagca
    36721 aataagcaac tagaatagaa aaagataggg ttctaaaaac tgacttctat tccttaaaaa
    36781 cgaaccagct tgactgattc gtcttcttac gtttatctcc tacttccgat acattttaaa
    36841 ctgtaggaag aggtcgctat atttccctgt ccatttatgg tcaaatttct cataaacttc
    36901 taggtgtttc atggtttcaa catctggata gaaggcctta tcttcctttg tttcctctgg
    36961 gagcaattcc ttcgctggta ggtttggtgt tgaatagccg acatactccg cattttggag
    37021 agcgttttca ggtttcaaca taaagttgat aaaggcatag gctgagtctt ggtttttaac
    37081 tgttttggga atgaccatat tgtcaaacca aagattgctg gcctctgtcg gtaccacata
    37141 acgtagattt tcattttttt ctaacatttg gctggcttca ccagagaagg tcacgccgat
    37201 tgcaacatta ttctgaatca tgtagccctt catctcgtcc gcaacgatag ccttgatatt
    37261 tggagtcagt ttgtagagct tatccactgt ctcttccaac tgctgcggat ccttggagtt
    37321 gaggctgtag ccgagggaat tgagtcctag tcccagcacc tcacgcgccc catcaaaaag
    37381 catgatagaa ttcttatact ccagcttcca aaggtcatcc caatgctcag gcgcttcatc
    37441 taccatggtt tcgttgtaga caattcctaa ggttccccag aagtaaggga tggagaattt
    37501 attacctggg tcaaaggact ggttgagaaa ctctggtccg atattttcga ttccttcaat
    37561 ttttgaataa tcaagcggaa ccaagaggtc ttcgtccttc atcttgttaa tcatgtattc
    37621 acttggaatg gcaatatcgt aggtcgttcc accctgcttt atcttagtgt acatggcttc
    37681 gttggagtca aaagtctcgt actgaacttg aattcctgtt tcttctgtaa actgagtcaa
    37741 gagttcagga tcgatatagt ctccccagtt atagataacc aatttttgac tatctcgact
    37801 attgatttta ctatctaaat gagtcgcaat tccccacaag acaaggataa tcgctgcaat
    37861 tcctgctaaa aatgaataga tttttttcat gcttgctcct ccttctcacg agagataaag
    37921 taataaccta caactaggat aatactaaag agaaagacta gagcagacag ggcattgatt
    37981 tctaaggaaa tccccttgcg agcacgagag taaatctcga ctgatagggt tgaaaagcca
    38041 tttcctgtta caaagaaggt cacggcaaag tcatctaacg aataggtgaa ggccatgaaa
    38101 taaccagtaa tgatagacgg agtcaggtaa ggaagcatga tttccttgaa catctgaaat
    38161 tgactagctc ccaagtcata ggccgcatga atcatgtcgc cattcatttc cttgagtcga
    38221 ggcaagacca tcaagaccac gataggaatg gagaaggcca cgtgactaga tagaacggtc
    38281 aaaaagccaa gtgaaaactt gagttgggta aagagaatca agaagctagc accaatcata
    38341 acgtcaggcg caaccatgag gatattattg agtgatagaa aggcttcttg gtatttctta
    38401 cgagactggt agatgtaaat ggcaccaaaa gtcccgataa tggtcgctat caaggctgat
    38461 aggaaggcca agaaaaatgt ctgagccaaa atcagcatga gtctcccatc tccaaacatg
    38521 gtttcaaagt gagtccagct aaaacctgta aagctattca tatcatcacc agcattaaag
    38581 gcatagccaa tcaagtaaaa gataggcagg tagaggacca gaaagaccag tcccagataa
    38641 aggttggcaa attttttcat cgttctctcc tttccttagt cacccacatg gtgatgaaca
    38701 tggtcaggat gagaatcaca ccgatggttg aacccatacc atagttgtca ttggttagaa
    38761 aattctgctc aatagccgtc cccaaggtga taacgcggtt cccaccaatc aaacgggtca
    38821 gcatgaagag actcaaactt gggataaaga ccgactgaac cccacttcgc acaccgttca
    38881 tagatagagg gaagatgaca tgacggaagg tctcccactt agttgcacca aggtcataac
    38941 tagcattgat gagattatta tccatgtcgt ctaagacatt gaaaatcggc aaaatcataa
    39001 aggggagctc gatgtagctt gcgacaaaga taaaggaaaa atcggtaaaa agcaactgtt
    39061 gtgaaccaat tccgataaat tccaagaatt ggttaataga gccattttga ccaaaaatcc
    39121 cgataaaagc ataggcttta aggagcaaat tgatccaggt aggaaggata atcagcatga
    39181 gccagagttg acggtgcttg agacgggtca aaaagagggc tgttggatag ctgataagca
    39241 aggtcacaaa ggtcacaatc cctgcataaa gcactgagtt gaaactcatt ttgaggtagg
    39301 tcaagttttg tgacgcaaag taagatttat aattttctaa actaaactgg ccttcaatgt
    39361 tgaaaaagga ttgtccgaaa atcaagacca agggtgccaa tacaaagagg gcaatccaaa
    39421 gcatgtaggg cactacaaag agtttagagc ttgttttctt catctctttc ctcctcgatc
    39481 gcattgatca gacctgcttc ttgctcttcg atttccacgt attcttcgat acgagcatcg
    39541 aactcttctt cggtttcatt gagacgcatg atgtggatgt cttctgattc aaagtccaga
    39601 ccgatttcct cacccacgat ggccttacgg gttgagtgga tcatccattc atttccaagt
    39661 tcgtcatagg cgataatttc ataatgaact ccacggaaga gctgggtgtc gaccttaact
    39721 tggagtttgc cttcttcagg aagggtaatg cgcaagtcct ctggacgaat aacgacctca
    39781 acaggttcat ttggcttcat cccaccatca accgcttcaa agcgtttgcc gttaaattcg
    39841 accaagtagt cctcaatcat ggtacctggc aagatgtttg actccccgat aaaggtggca
    39901 acaaagtggt tgattggctc atcgtagatg tccacagggg ttccagactg gacaatctcg
    39961 ccatcattca taacgaaaat ccagtcactc atggcaagag cttcttcctg atcgtgagtg
    40021 acaaagacaa aggtaatgcc caatcgttgt tgtaattcac gcaattcgta ctgcatgtct
    40081 gttctcaatt tcaagtccag cgctgataaa ggctcgtcca acaagaccac acggggttgg
    40141 ttgatgatag cacgggcgat ggccacacgc tgacgttgtc ctccagaaag tttgcggatg
    40201 gaacgttttt cataaccttc caactgaacc atcttgagaa cttccgctac acgctgctcg
    40261 atttctttct tatcaatttt acgcaagcga agtggaaagg caacattttc aaacacattc
    40321 atatgtggga acaaggcata ggattggaag acggtatgta cgtcgcgctt gttggttgga
    40381 atatcattga tacgaacacc gtctagcatg atatctcctg tcgtcgcatc cagtaaacct
    40441 gcaataatgt ttaggatagt tgatttcccc gaaccagatg cacctagaag ggtgtagaat
    40501 ttcccttctt ccaactcaaa gttgatgtct ttgagaacct tggtgttgct gtcttcaaaa
    40561 actttagaga cgtttttgaa ttcgataatt ggttttttca attggcataa attccttctt
    40621 tttcatagat taaccgatcg gggctctgtc aggtccccac tacctcttgc agggagtaaa
    40681 accacctgca tacatcttcg ctaccgatag gctttcaccc aagatccgga cttctctttc
    40741 aagcgtaata cctgagtgtt ccttgacttt ttcgataacc gattggatca agtcctcgta
    40801 gtctttggcc gttccatctg cgacattgat cataaatcct gcatgctttt ctgacacttc
    40861 tacgccaccg atacgatagc ctttcaagcc agcttctgaa attaactgac ctgcaaaatg
    40921 cccgactgga cgcttaaaga ccgagccaca agatgggtat tccaaaggtt gcttgagttc
    40981 acgtaggtgc gtcaagcggt ccatttcctg cttgataacc tgatgggttc ctggagctag
    41041 ggcaaattta actgacaaga caactgcacc agactcctga atagctgaat ggcggtaacc
    41101 aaaagccaag tctttagcag acagggtttc gatttctcca tccttggtca agaccttaca
    41161 agactgcaag atgtgagcaa tctcgccacc ataggcaccc gcattcataa agacagcacc
    41221 gccaacgctt cctggaatac cacaagcaaa ctcaaagcca gttaaactat gacggagggc
    41281 aatgcgagtt gtttcaatca agttagcccc agcttctgct tcaatggtat agccatcaac
    41341 agaaacgtta ttgagcttgt cacacaagat gacaaatcca cgaatcccac catcacgaac
    41401 gatgatattg cttgcattgc caagaaccat ccaagggata ttttcttggt tggcaaattt
    41461 cacaacgcga gccaactcaa aacgatttcg tggaaagacc aaataatcag cctctccacc
    41521 tacttttgta taactatagc tatgcaaggg ttccttaaaa cggatatcaa ttccttctaa
    41581 gatttcaagc attttttctc ttacagacat gtcactcttc cttttacaaa attcattcca
    41641 ttataccatt tttagagaca tttgacgacc ataaaaatac cttgtttgga ttttgcataa
    41701 gaaaaagagg ttcccccctt tttatgattt tttacaaaag atttccttgg ttccataggc
    41761 gatcagaacg agctccagtg ctagaatcac ttcaaccaag actggatttg tcaaccagcc
    41821 tacttggaaa agagatggtg ccagatcaaa gaaggcatgc aagccatagg ctgttaggag
    41881 ataaatccat ttcttctggc gaacagcttg ataaacccaa actgtcaaaa gtaattggaa
    41941 accaagcgcc aagattcgct caaaaccaag caaataaatc tgccagaccg aaagtgactg
    42001 aatggttttt aacatatttt cagacagtaa ttgcataacc tgtggattct gagtttgaac
    42061 tgccgaaaga acaatgtaaa gattgagtaa actagtaagg cctagaaaaa tcaactccaa
    42121 gccaccatgc cccagtccat aggccaaggc gtctgccttt tccaaactta tctttttctc
    42181 caaccatttg aagaaaacaa gacgagccgt ttcctcaaaa aatgctgcca tggctaggcc
    42241 atagataata tagacaagcg ggtgatcttg caagagggca atactaccgt ctttttgagg
    42301 atgcaaaatc aagatatgca ccagtttttc caaaatctgc gaagagacaa agaaagcgac
    42361 tgcacccaag cccaagacag ctagattaat ctggtatttc tttttggcaa accaaatgct
    42421 tcctatcaga aaagctagca acagcaacat ggtaataatg atatgaatgg tcattttctt
    42481 ctcctattct gccttttcaa tatctttttt catctcgtca acattgaact tagcaaacaa
    42541 gtattgacgg tcttggactg ggaaacgttg gtccaactgg tcaactgctc ccacctcgat
    42601 aatgccttcc ttgatgacaa aatccatgac atgtccaccg aaggtcaaat catctgatat
    42661 gaagtgcaga tggtagcctg ccacactgac cccatggaaa atctcaggcg tccagaaacc
    42721 aacaatagtc cccacaacat tgtcacgact atattccggt tgatgggttg cgacatcagc
    42781 aaacttggta tcgggtgttg acttaggaat catacgcaca tgcatatgtg aaaattctcc
    42841 ccgaatcttg atagagcgga aaagattttc cccatcataa taagactcaa ttcgttcttc
    42901 caattccttg tctgtcatct caaagcgctg gcggaaaatg acctctgcct gatgcggtac
    42961 tactgctgca taaggaataa gggcatctgg tgacacttcc acaatttctg gctgttctcc
    43021 tgttcctttt gcctgataag ccttgccatc taagacaatc aattccccat caatagaatc
    43081 caaggttccc aaaccaaggt caccatgctc tagcaattct cccactgtca tggtaccacc
    43141 ataaaggcca gccatcaagg ctccaagagt attgtattga aataatttca ctggttcctg
    43201 cacgttctta tccattcact ttcttgtctg ttattctata aatcttactc ctaagtatac
    43261 cacatttgcc cctagatgtg aacgagagaa acgctctaga cattgccaag aaggaaaaaa
    43321 aagggtacaa tgtaacaaaa tcaagggagg tctggaatga agagacaaag caagtacaaa
    43381 gaggtcgttt cctatctgaa aaatggtatc gagtctggac gatttccgac gggtagtcgc
    43441 ctgccttcta tccgtcaact gagccttgac tttcactgca gcaaggacac cattcaacga
    43501 gccctgctgg aattacggca cgaacaatac ctctatgcca agcctcagag tggctactat
    43561 gtattagaac aagggcaaca tcaagaccta gaaatcgagg ttaccgacga acatgccagt
    43621 gcctatgacg atttccgact ctgtgtcaat gaaaccttga ttggccgaga aaactacctc
    43681 ttcaactact atgacaatca agaaggatta gaagacctaa gacagtccat tcacaaactc
    43741 ctctttgagc aagctctcta ctgcaaggct aaccaactag tactgacttc tggaacccaa
    43801 caagccttgt ttatcctctc tcaaatatcc tttcctagac aagccaagga aatcttggtg
    43861 gaacagccaa cctaccatcg gatgaatcgc ctcttgattg cacaggggct ggactatcaa
    43921 acgattgaac gaggcattga tgggattgac ttggaggagc tggaaggcca cttcaaaaca
    43981 ggaaaaatta aatttttcta caccattccc cgatttcact atcctctggg acattcctat
    44041 tctgagcaag acaaacgatc tattcttaac ttagctgcca agtatgatgt ctatatcgta
    44101 gaggacgatt atctgggtga tttggactcc aagaagggcc aaaccttcca ctatcttgat
    44161 acagaggagc gtgtcattta tatcaagtcc ttctcgacca gcctttttcc tgcccttcgt
    44221 attacagcac tcattcttcc aaatgctatc aaagaagcat ttatggccta caaaaatatc
    44281 ctagactacg acagcaacct cattatgcaa aaggccctgt cactctatat tgacagtcaa
    44341 ttgtttgaaa aaaatcgttt ggctcgcttg accaatcatg aatcttacca aaaacaaatc
    44401 gaggaaagga taactaaaac accttgtccc cttcctcatt atcccctaca cgatggttta
    44461 ttgctagacc tgagacagta tcctaaaatc gccagtctca aacacagtca actgggcttg
    44521 gacttctttg aagaggccta tttaagcacc tgtccttatc aatttgccaa ggtgtcccta
    44581 gacaatctgg aaaatgtttt aaactattta aaagcagaat tggaatgaca tccaactctg
    44641 ctttttctta ttcttcaact tcagttagac ttgctgcttt ttcaagatag ctttggtaag
    44701 ttccttcatc cttaagtttt tggatgacct tgtctaccac ttctttcaaa tcatcactat
    44761 tttttctaag tgcaacggca ttggcgtcgc cgtccttcat cttcaagctg acagttgcga
    44821 cagctaagcc agcgttttta gcagcataac taagtgcaac aggctcatcc atatgaacag
    44881 catctatttt tccagcctgc aattcattga ctgcttcacc catattagtt agggaagtta
    44941 attgagcttt tggcaattgt tccttgacca ttgattctgg aacagtccct ttttgggctg
    45001 caatattagc actttctagg ctagttaaat ccttgtattt ttccacatca gccttacgaa
    45061 ccaagaaact aatcttgttt tcatagtatg ggattgaaaa atcaaagact tcttttctct
    45121 cgtcagtagc actaattcct gcaactgcta ggtcagcctt accagtttga agactggtca
    45181 aaacattgtc aaaactcatg cttaagattt ccaacttaac cccaagttca tcagcgatag
    45241 cttgagccat gtcgatgtct gcaccgacta cctggttctt tccatcaacc aatgattgaa
    45301 attcaaaggg tgcatagtca ggactggttg ccacaactaa tttccccttt tgcttaatgg
    45361 cctcaacagc tgactgagaa ccattagaac ctgactggca agctactaag aagaaacttg
    45421 caagaaaatt acataaaaca aatatccatt tttttgattt cataaataaa caacctttct
    45481 gttaattttg tataattata acaatatcca agttacttgt caagtgtttt ttaaattttt
    45541 atctcaaaaa tattttttcg ttcaaaaaaa ggagccatca gttgatttca agctcctttt
    45601 tatacagaat taaactattt tatagttcga caatcttacc tgtttcaaag tagacaaccc
    45661 attcacagat atttttagca tagtcaccga tacgctccaa gtaggaaata acttggaaat
    45721 aatcacgacc cgtaacaatg gcttctggat ttttcttaat ctcttcagtc gcaaggtcac
    45781 ggatagtttc aaaatagtgg ttaatttgct catccatgga ggccacccgg tatgcgtcgt
    45841 caacagaacc attaagataa agatcaagtg ctgcttcaac aacgctttta acttcacgtc
    45901 ccattttttt aatttcttcc tctacagctg ggatgcgttc ttcccccttc atacggatgg
    45961 ttgcctgggc aatggctaca gcgtgatccc ccatacgctc cacatctgat acagccttaa
    46021 ggacagtcaa gactgtacgc aaatcttgag agactggttg ttggagtgcg atcatttcaa
    46081 atgatttctt ttccagtttc acttcgtatt catttacttc tgcatcatct tctatgacct
    46141 cttttgccag gtcacggtca tgcgtgacaa aagcacgtac cgtacgattg atttgtgaga
    46201 gcacttcttg tcccatagcg tagaactggt tatgtaattt ctctaaatct tcttcaaatt
    46261 gagatcgtaa catctttcat ctccttatcc aaattttcct gtaatatagt cttccgtttc
    46321 cttgtgttgg ggatcaagga acatctgctt ggtatcatta aattcaatca aatctccatc
    46381 taggaaaaat cctgtcttat cagagatacg tgaagcttgc tgcatggaac gggttaccag
    46441 aagcatggtg tacttgtctt ttagaccata caaggtttcc tcaattttac cagctgaaat
    46501 cggatccaaa gccgaagttg gctcatccaa gaggatgatt ttaggactag ttgccaagac
    46561 acgggccacg cagacacgct gctgttgacc acctgacaat ccaatagctg aatcatatag
    46621 acgatccttg acctcatccc agatagaggc accttgcaag gctttttcta cggcttcatc
    46681 cagaacctgc ttatccttaa ttccattgat acgaagcccg tagacaacat tctcatagat
    46741 agtcataggg aaaggattag gttgttggaa aaccattccg atttccttac gtaattcaac
    46801 cgtatctgta cgcggactgt agatgttgtg accattgtac accacggatc cagttgtggt
    46861 cacctctgga ttgagatctc ccatgcggtt gagagacttg aggagggttg acttccctga
    46921 tccagatgga ccaatcaagg ctgtaatttc cttaggttgg aaagataggg aaacactatt
    46981 caaagccttc tttttattat aataaacgga caggtctgat acctgtaaaa tcgcatctgt
    47041 catacggttt cctttctaac caaagtgacc agatacatag tcattggtgg actgtagctt
    47101 ggcattttgg aaaatagttg cagtcttgtc atactcaatc aaatcaccca agtaaaagaa
    47161 gcctgtatag tcacttgcac gagcagcctg ctgcatatta tgcgttacaa tgatgatggt
    47221 aaagtttttc ttgagctcaa acatggtctc ttctagttgc atggtcgcaa tcggatccaa
    47281 ggctgaggct ggctcatcca ttaagaggat atctggctta acagagatgg cacgagcgat
    47341 acagagacgt tgttgctgac cacctgataa ggtcaaggct gacttgtgga gatcgtcttt
    47401 aacctgatcc cagagggcag cctgacgaag ggaggtttct acgatttcat ctaggacttg
    47461 cttatcctta actccagcac gttcatgcgc aaaggtaata ttacggtaaa ttgacttagc
    47521 aaatggattg gggcgttgaa aaaccattcc aatgtgttta cgcatttcat aaacgttgat
    47581 ttctggacgg ttgacatcaa ttccacgata gagaatctgc ccagttactt tagcaatatc
    47641 aatagtatca ttcatgcgat tgagactgcg taagtaggta gatttccccg accccgacgg
    47701 accaatcaaa gctgtaattt tatttctttc aaattgcata tcaatcccct taatggattc
    47761 atttttacca tagtaaacat ggacatcctt agtagaaagg gctacttttt cttcaggaaa
    47821 ggtaaggata tgcttctcat cccagttata tgttgacatg gcttctcctt taggcagcgg
    47881 ttaatttctt gtgtagatag cttccgaact tacgagctcc aaagttaaaa atcaggataa
    47941 agatcaggag cacagcggca gaacctgctg atacaatggt tccatctgga atagtgcctt
    48001 cactattgac tttccagata tggacagcca aggtttctgc ttgacggaag atagagatgg
    48061 ggctagtcac actgaggata ttccagttag accagtcaag agctggcgcc gattgccctg
    48121 ctgtatagat cagagctgca gcttcgccaa agatacgacc agatgccaag acgacacccg
    48181 ttacaatacc tggaagcgct tctggaataa caacatgaac cactgtctcc cagcgagaaa
    48241 tcccaagagc cagaccagcc tcacgttggg tatggtgaac gtgtttcaaa ctatcctcta
    48301 cattacgcgt catctgaggc aaattaaaga ctgtcaaggc caaggcacct gaaatgattg
    48361 aaaatccata ctcaaactgg actacaaaga tcaagtaacc aaagagaccc accaccactg
    48421 atggtaaaga ggacaagatt tcaatacaag tccgcacaaa gttggtaaca ggaccttttt
    48481 tagcatattc agccaagtag atcccagctc ccatagaaag aggtacagaa ataatcaagg
    48541 taatgaccaa taggaaaaag gaattgtaaa gctgaatgcc aatcccacca cctgcttgaa
    48601 aagcagaaga ccttccagtc aagaaagacc aagagatatg gggcaagccc cgaaccaaga
    48661 tatagagaat caaggaagcc aagattgtca caatgatgct agcaatcgta tagaggacag
    48721 ctgttgcaag tttatctaat ttcttagcgc gcataatttt tctttcctct ttctttcgta
    48781 atcaatttaa tcacactgtt aaaaactaaa ctcatcaaga gcagtaccaa ggccagtgac
    48841 cagagaacat tattatttac agttcccatg acagtgttcc caattcccat agttaatata
    48901 gaagttaaag ttgcagctgg tgtggtcaag gaagttggga taacagctga gtttccgaca
    48961 accatctgga tagctaaagc ctcaccaaag gcacgcgcca tcccaaagac cactgcagtg
    49021 aaaataccag aacgggccgc cttcaagatc acacgccaga tagtctgcca gcgagtggct
    49081 cccatagcga aactggcttc acgataataa cgaggaaccg cacgcaagct atccgttgtc
    49141 ataaaggtta cggtcggcaa aatcatgaca aagaggacgg aaatccctga caaaatccca
    49201 aaaccagtcc caccaaagac actgcgaaca aagggaacga cgacttgcaa gccaataaat
    49261 ccgtacacta ctgaaggaat cccaaccagg agttcaatag ctggttgcaa aatcttcgcc
    49321 ccttttggtg atacttcggt cataaaaact gctgcaccaa tagcaaaggg ggttgcgata
    49381 agggctgaga gaatggtaac gataaaggaa cccaaaatca taggaagggc accaaattct
    49441 ttactagaag gattccaagt tcctcccaaa agaaagtcaa agatattcac accattgaca
    49501 aagaaggtcg acaagccttt ttgcgctacg aaaaccaaaa tcatggccac aaggatgact
    49561 atcaaagaaa gacaggcaaa ggtcaaacct tttcctaatt tctccagacg agaattcttt
    49621 gatggaagca acattttctt agctaattct tcttgattca ttattgtctc ccttccaaca
    49681 ctgtcacagt tccggcagca tctttttcaa ccttcatttc cttaatcgga atatacttca
    49741 atcctttgac aatcccttct tgggtctcat ccgagagaac aaaattgaga aattctgcag
    49801 ccaactcatt gggctgcccc aatgtataca tatgctcata agaccacaag ggccaattat
    49861 tgctacttat attttctgga cttaagtcat agccattcaa cttcatgctt ttgaccgaat
    49921 catctatata ggtaagagat aaataagaga tagctcctgg actttttgat acgattgatt
    49981 ttaccgctcc atttgaatcc tgctcctgac tttgcatggc agactgacct tccataatga
    50041 cagtatcaaa ggtagcacga gaaccagagc cggctgcccg attgataaca gagatgggta
    50101 agtccttacc accaacctct ttccaattgg ttacctcacc tatgaagatt tgacgaagtt
    50161 gctctgtcgt taggttatca acatcaacct ccttattgac aatcagagcc aagccagcta
    50221 ccgcgacctt gtggtcaaca agagcagaag catcaattcc gtctttttcc tcagcaaata
    50281 catctgagtt tcctatatca actgccccag actgaacctg ggacaagcct gtaccagaac
    50341 ctcccccttg gacattgacc gtttttccaa catggatcgt gccaaattca tctgccgcta
    50401 cttcaaccaa gggttgcaag gcagttgagc caacagccgt tatggattct ccacgatcaa
    50461 tccagctagc acagcctact aaacaagccg tcagccaaaa agcgataaga gacagagcaa
    50521 gcttttttct ttttttcact gtttttctcc tcgaaaataa ttatgaatac tgtgaatttt
    50581 ttaagtagtt ctttatgagt tgacgcatga attcttacca aatttctgcg caattgatta
    50641 tttatataat ataggctata ttactctttc ctaacctcct tttttcatat gtggataaaa
    50701 tctcttgtct atcccttccc ccattgtcac ccattatagt catttcgtgt ctctttttcc
    50761 cctttttaat gcaagggaaa ttactctcct tagatgataa tccaaaagct agaaaggtat
    50821 ctcaaacctc tctactctcc cagactagtt tacaactaaa aggaaaagat tcgattttat
    50881 gagaaatcta gtttacaagc ggtaagaacg ctaataacta aacttcttgt actctttgaa
    50941 aatctcttca aaccagtgtt ttgagctatc tatggctagc ttcctagttt gctctttgat
    51001 tttcattgag tagtaaaact acatgtaatg gcaatcaaga tatcaagaat catcctacta
    51061 aaaaaatcca tactttcact ataacataga ataagatatt tgactagcat tttcatttga
    51121 atctgaggcc ttttggaaaa taatttttca aaacatttcc agtaaccttt gcaaagccca
    51181 agccattgcc tttaaccaaa acttggtacc aaccatttgg cagactttct gccagctgaa
    51241 cgatttctcc agccgcatac ttgacaaact cttcttggcc aatttcaacc gactgttcga
    51301 cctgactcgg tttcaaggct aaaccaagag cgaaactggg ctcaaagcgt ttcttcttaa
    51361 aagtacccag atgcagtcca ttgcgagcaa tcttgagctt ccctaaatct ggcaaaagtt
    51421 ctggcaagag ataaagctgg tctccaaaaa tctgcaagat acccggtaga ttgaccttca
    51481 aatggttttg ggcaaattcc tgccacaagg caacttgttc acggctgagg ttactcttac
    51541 ttgccttaaa tttaggagct ggattgttac ccttaaactg tagatgggca acaaactgac
    51601 cctctccctt aaactgatga gggtacatcc gagccgtttc tggcaggtca ataccagcta
    51661 ccattccatt gatatgctct actggcaaca agtcaaaatc atactcttcc agcaaccaat
    51721 tgacaatctc ttcgttttcc tcgggtgccc aggtacaggt cgaataaacc agacgaccac
    51781 cttcagctaa catggtcact gcatcctcca gaatttctct ttgcaagcta acacattgac
    51841 tcggataatc taagctccaa tagtccatag catcaggttg cttacgaaac attccttcac
    51901 cagagcaagg ggcatcaaga acgattaagt caaaatagcc tttaaagacc ttgaccaagc
    51961 ggtcggcaga ttcattggtc accacgacat ttgtcgctcc aaaacgctcc atgttttcaa
    52021 ccaaaatctt agcccgtttg cttgaaattt cattggaaac aagtagcccc tcccctgcta
    52081 gataggctgc cagttgagtt gatttgcccc ccggtgcagc agccaagtcc aagaccttca
    52141 taccaggact gggttgggct acttgagcca ccatttgagc agcaggttct tgcgaataaa
    52201 ctaaacctgt agcatgctca ggcgatttcc ctgaaacctt cccatagtgg ccccaagggg
    52261 tttgagtaat ggcatcagaa aaggaaagtt gctcttcttt taagggattg acccgaaagg
    52321 ccgaaaccgc ttcctcctca aaagaggcaa gaaaatctct tgcctcatct cctagtattt
    52381 ctttatattt ttcaacaaat ccttctggaa atttcattta agttcttttc ctttcgtaaa
    52441 tataggactg aatttcctcc tgcatctcaa gaggcaccat catgaccggc tgtctggttt
    52501 gaaaatcagg agcttcacca aaaagggtca caacccgata gcccagactt tcccctaaaa
    52561 tactagctgc ggcataatcc catggttgca gataggtgag ataggtcaac aaatgccctg
    52621 acaaaatctt ggcaaaacta atggccgcac ttccatagac acgaacacca agaaccgctc
    52681 ggctcaaatc agccagcccc cattcattgg tttccagcat accactattc cctgcaatga
    52741 gaaaatctcc aagtggttta gttttaaaag gagctagggg cctatcattt agacaaactg
    52801 gaaattcccc accaccgtgg taacaatccc ctttgaccac atcataaatc agaccaaact
    52861 gtccctgacc attttcaaaa taagccatca taacagcaaa atcttcctgc tgggctacaa
    52921 aattattggt accatcaatg ggatcaatga cccaaacctt gccctcttga accgaggctc
    52981 gcagacaacc ttcttcagca caaatcttat cctcaggata acgagacaaa atctcaccaa
    53041 ccaagagttc ctgaacttct ttgtccagtc tggtcaccaa atctgttgga gaggacttgg
    53101 tttcaacacg caagtcttcc tgcatatggt caagaatgta ctggcctgct ttcttaacaa
    53161 gccctttagc aaattcaaat ttactttcca agagaaatct ttccttcccc tttttctttg
    53221 gcagcctgaa ctgctcggta aagtgaatag ccactaaccg tttcaaattc tcgtcccaaa
    53281 cgtttctctt cgctcttgct tggcacgacc gctttgaatc ccttatagga gtccagtaac
    53341 tttttagcct ctactttgcc ttcataggca gcttcaacat cattaaaaaa agaaagcact
    53401 gaagcaagtt cttcagtgct ccacgacaaa tctagtgggt aactatactg tttgttcatt
    53461 aactaatacc agctctcatt cttgcttctt ttagttcttg cttacgataa ctacgaggga
    53521 gaaaagcacg aatctcatct tcattaaaac cgatttgcat acgcttggca tcaataataa
    53581 ttggacgacg caaaagacta ggatactgct caatcaaatg aagcaattcc gataccgaaa
    53641 tactctctac atcaatattc aatttttgaa aaatttttga acgagttgaa atgatgtcat
    53701 cagtaccatt ttcggtcaag gaaaggatgt gttgcaattc ttttcttgtt aaaggactgg
    53761 tcataatatt gtgttccaca aagggaacct tatgtttttc taaccaggcc ttagccttac
    53821 gacatgatgt acagctcggt gatagaaata gtgtaatcat gcttttctct tcttatctat
    53881 actttgctac ttctattata caaaaaaata aggcgcttga ctagggattt ttagaaaaaa
    53941 agcctatttt ttcaagaaaa ataggctttt tgcgaacgat tgacacaatt ggatttggtt
    54001 aattcactct taacgatggt tttaaacgat atatatattt atatatgtaa attaaaaaca
    54061 tctttccttt cacttcctac gacttttcag atacagatag ccaaagaagt tttcatagag
    54121 ggcaaaaaag aggaggaagg cgtgaagaaa gaaggtctct ggcaaaatca taataacagg
    54181 atccttggct ggatcaaaaa gccaggtatc atctcccaca aagagaattt gatggaaaag
    54241 agtaaagaat tggtcaaaac caatcaaaac tcccccaagt ccaatcatca caggtaagac
    54301 tactagagcc aggagacttt ttcgataaag agacaaaaag tcctttttca caatcctatt
    54361 gacaaagaca tagaaacttg gcagtgtcac tagagctact agctgaacca aatgaaagag
    54421 attcttgacc actgcgaaat ggtgcagacc agctgctgac gaacgaaaat caggcatctg
    54481 taagacctga ctaaaaggat tggtcagata attcatcaag atatgaaaat tgtattgaac
    54541 ggtttctggt tttagataga ctcgattcgt taagtttagc cactgaatct ccataggata
    54601 gaaaatccaa gccagataaa tggtcagaag gattgagagg gagaggagaa agagcataga
    54661 gccccaaaag gtcaatttag ttttcatcaa aatcccactc cgcaaggcta gaaaccacat
    54721 gtgtcggtgc gattggcagg ccagctactt cttctgcctt agtaaaacct gtcgtcacca
    54781 agagcgttgg aatgccattg tcaatcccag cccggatatc agtcaaataa ttgtccccaa
    54841 ccatgattaa ctcttcacgt tccaaaccta agtgctcaac cgccttgtcc ataatgatgg
    54901 catttggttt tccgatataa accggcttca ctcgtgtcgc tacttcaagc agcgtaatca
    54961 gtgagccagt acctggcaaa agaccacgtt ccgtcgggat gttgaggtca ggattggttc
    55021 cgataaaatg ggcacccttt tgaatagcaa gagttgctgt ggcaaatttt tcatagtcga
    55081 cttgccaatc cagaccaact accacgtagg cagggttttc cttgtcttcc acataaccag
    55141 ccgccttgat ggcttccttg agtcctgctt ctccgacgac atagacagtc ttttcaagcc
    55201 ccaaatcatt catatagtcg atggttgcca aagtcgctgt gtagacagtc gatagaggcg
    55261 tatcgatatt aaaattctga gccaacatct ccttaacact ctctggagtg cgggttgtat
    55321 tgttggttac aaagagatag ggaatgtccc gcttttgcaa ttcatgaaca aaagtctctc
    55381 cagcagggat tcggtctttc cccttataaa tggttccgtc taaatcaatt aaatagcctt
    55441 tatatttcat ctatttctcc ctaaaccttt tttatttctt gccaagtaat gattgcttgg
    55501 gcattgataa ccccatcact tgtaatttca tgcttgcttt ccagtccagt ccgttcaaca
    55561 gccgatgtaa tcaccccacc tggtcgaact tccttgacat acttgaggtt gattttcttg
    55621 ggaatatagt gggtcaaaaa atccgctccc atgacctcaa aaatccagtc caagtattta
    55681 ctgttattga catgaccatt catatccaag tcgtaaaaac gaacatggta atccttgctg
    55741 atcggctctt ccaaggattc atacttcggt ccacggataa gttttttatc aaaatcagac
    55801 tggtaaggag ccacaatctc aggttcaaca gcatggactt ttcgactgtc gcggtccatg
    55861 agaacaaagg tcgccatcat atggatgagc tcctgccccg cttcattata aatagtaaag
    55921 cgacggtagc aaaaaagtcg attgtagctc aaggcttccg tttcgatggt aatttcttcc
    55981 gcaaaacgag gcaaacgaac cacctcaata tcatattctg cgataatcca gaccagatta
    56041 tagtcttcca aaatggcctt atcactaact cccagttcaa tcgattgcat ccctgaaact
    56101 tgcagtgaca gcaaaatcac atctggaagt ttgatatgac cgttcatatc agccatatca
    56161 aaaggaattt tcattttcat ttgataagtt aagcccatga tcctactcca aaataaatcg
    56221 ttctgctaca gtatctccca aaaagagacc tctctttgtc atgcgaacgt ggtcaccctc
    56281 aatctgcatg aggccttgtt gaaccaaatc tctgacaatt tctccataaa gtccagcaaa
    56341 agactgtcca aatttttcct caaatcgcgc catggaaacc ccggatttct tgcggagtcc
    56401 caagaacatt tcttcttcca tttgctcctt ttgactcagg tgatcttctg taatacaagc
    56461 attgccttcc tcaaccgcac tgagataatg acgaatggga ccatgatttt tatagcgtac
    56521 tccattgaca taaccagatg cccctgcacc aataccatag tattcagcat tgtcccagta
    56581 catgagatta tgacgacttt caaagccggg tttggagaaa ttagaaatct cataatgctc
    56641 aaaacccgct cgctccagct ctgcaatgat gtactcaaac atctccgctt ctagttcctc
    56701 cttaggcaga ggcaatttcc cacgtcgcat ccggttcata aagaccgtat ggttttctaa
    56761 aatcaaacta tacaaactca tgtggggaat atccaatcca atggctttag ccacattttc
    56821 ctttacttgc tccatggtct gaccaggcag agcataaatc aaatcaatgg agatgttgtc
    56881 aaaaccagcc agtttcaggc gatcgatatt ttcataaata tccttctcca aatgactgcg
    56941 cccaatcttt ttcaacatct tatcatcaaa ggtctggaca cctagcgaaa cacgattgac
    57001 agccgaattt ttcaaaacag ctatcttatc cgcatccaaa tcgcctggat tggcttcaat
    57061 ggtcaactct tccaagacag acaaatccaa gtttttagtc aagccattca gtaacacctc
    57121 cagttgcgga gccgacaggg ctgtcggtgt tccaccaccg atataaaggg ttgacaactt
    57181 ttcaatatca taagaacgaa actcttccag cagatgctct aaatagctgt cgactggctg
    57241 atttttgatg aagacctttg aaaaatcaca ataataacaa atctgggtac aaaatgggat
    57301 gtgcacatag gctgacgttg gttttttctg catagtaatt attataccac aaagactaga
    57361 ttccagataa aaatcaccat ccccagatac atagtccgtc cggagatggt gatggtttat
    57421 tcttctgtta tatcaatcac aatctcttct gagtcatcaa gagcttcggc tttttcttgc
    57481 cattgttcct tgagattatt taattgattt tttgatgctt ctgtcgcttg aaaagcatag
    57541 gatttagctt gagcaagtat actgtccaca gtgatttcac ctgactcaac ctgttctttt
    57601 gttttcagaa caaaatctgt agcctgctcc ttaacttctg tcagtttttc acagacttgc
    57661 tccttggcat actccggatc ttctctcaaa tcatctagaa aatcttgagc ctgactgcaa
    57721 acttgtttgc ccttatcact tgttaaaaac aaggcaagag ctgcacctga aacggttcct
    57781 aaaaggattg aggataattt acccataagg attctccttt tttatttttt gaaaaattta
    57841 cttgcaagac gaagagctga cagacttgca ccagtcttga gtgtttttga accagctgat
    57901 gaagctttct tgctcaagac acgcgcatgg tcattgaggt ctgaaacaga tagagataaa
    57961 tctgcaacag cactgaagag tggatcaatc gtagccacct tgacattgat atcatctgcc
    58021 aagacattga ccttagccaa caactcattg gtgtgatgca aggtcacatc cacatctgaa
    58081 gtcaaggttt taatcgtctt ttctgtttca tcgatgacac gaccaagctt ttgtacagta
    58141 atgatcagat agaccaaaaa gacaatcaca gctagggcaa caagaatata tgcaacttct
    58201 aacatttagt tttcctcctc tgtaatatag taaggggcct tctttcgatt ttgataaata
    58261 acgatcatta taccgagacc gataaagaca actgacagcc attgggacac tcgaaggccg
    58321 aagaacatga gactatctgt tcgcatacct tcgatgacca tacgaccgaa accataccaa
    58381 atcaagtaaa aggccgtgat atgacctcgt ctgagactct tccatttccg tctaaaaatc
    58441 agaatcaagg caaagccaag cagattccat agagactcat aaaggaaagt cggttgacgg
    58501 tagctcccct caatatacat ctggtcacgg ataaagccag gtagataatc cagattatcc
    58561 actgttgcac cataagcttc ttggttaaag aaattacccc aacgccccaa actttgagca
    58621 atcataacgc taggcgccgc aatatctaga aaatcccaag tattgatgag tttacggtca
    58681 gcaaagatat agagcacaag agccccagtt atcaaaccac cgtaaatggc caaaccacca
    58741 ttccaaatgg caaaaatctc tcctaaattc tgactatagt aatcaaatcg gaaaataaca
    58801 tagtagagac gagctcctaa aatagccaag ggaaaggcta ctaagataaa atctaaaata
    58861 tcgtctggta tgatcttctt tctaggtgct tctttcatgg tcaaataaac cgcaagaatc
    58921 aagcctgtca caatacataa ggcataccaa cgaatggcta ggggtcctag ttgaatagca
    58981 attggatcaa gcattttgca cctcatttcg agctatgaga cttgtcagtc gttcgtcgaa
    59041 caaacgggta gcatcaaagc ccatttcctt ggcacgataa ttcatggcag ctgcctcaat
    59101 cacaacagag atattacgac ctgttttaac tggaatacga atacgaggaa tggctacgcc
    59161 agaaacttca agttcctctg cattgtttcc aagacgatca aaggtcttat gcgtatcgta
    59221 attttccaaa tagacagcaa gctgaacctg tgaagaatcc ttgacagcac tcgcaccgta
    59281 gagactcata acatcgataa taccaacccc acgaatttca atcaagtgtt tcaaaatttc
    59341 agctggttca ccccagagag taatctcatc cttggcaaag atatcgacac ggtcatcggc
    59401 taccaaacgg tgaccacgtt tgacaagctc aagacctgtc tcgctcttac caattccact
    59461 atctccctga atcaagacgc ccatcccata aatatccatc aagacaccgt gcacactggt
    59521 acgttctgcc aaacgagaat ccagatagct agataactct ccagataaac gactggtagc
    59581 tgcacggctg gttaaaatag caatcttaca ttctctagca gcctttaaca tctcctctgg
    59641 aaccaccaaa ccacgggcaa caatgactgc tggtgtctca ggtagaaaca tttttttcaa
    59701 aacttcataa cggctgttgg aaggcatgct gatcagataa gaccactcct tcatccccaa
    59761 aagttgaatc cgctctggtg tatagtagtc aaaatagcct gtcatttcaa gaccaggtcg
    59821 cgtaatatcc gctgtattga tttccttttc aagcaattct ggttcaccat agacaatatc
    59881 tagtctaagc ttttcaatca cttcttttac taaaaccgac atcatttcct ccttcaaatg
    59941 aattcttctc tctattatat caaattgtag gaggaagttt cagatttttg caggctttgg
    60001 agtatttatt taaaagaaaa aggactagat ttctctagcc tttcatttca attagaattt
    60061 tttacgttta cgagctactt ctgatttacg tttacgtttt acagaaggtt tttcatagaa
    60121 ttcacgtttg cgtgtttctt gaagagtacc agctttagta accgcacgtt tgaaacggcg
    60181 aagtgcgtcg tcaagagatt cattcttacg tactactgtt ttagacattt ttttcactcc
    60241 cttcaagttc aatatctatt tcattctaca cgtaaaagga ataattgtca agcaaaaatg
    60301 cggtttaatt ttgatttttt cttccattta tacaagagtt gaaagcgttc aatagaacat
    60361 tgctttttta tttttcgagt aagctaagcg cttcagcatc tgcgatgatg gttacatcag
    60421 ggtgattttg gaggctactc gcaggtaggt tctcagtcac tgggccagat actgttccgg
    60481 caatggcttc tgctttcgac tcaccataag caaaaagaat aatagacttg gcatccaaaa
    60541 tgtttttaat ccccattgaa atagcttggg ttgggacgtc ttcaatcttg gcaaagaagc
    60601 gagcattggc ttcgatagta gactggtcaa gttctactag atgcgtttga ctgtcaaatg
    60661 gagtaccagg ctcattaaag ccgatatgcc cattgcgacc gattcccaag atttggaggt
    60721 caactggatg gtcagccaaa atttggttgt agcgttcaac ttcagcttca gcattgtcct
    60781 taacaccacg aggcaagaaa ctttctttaa atggtttttg gttgaacaag ttttcttgca
    60841 tgaagtaacg ataagactgt ggattgtccc catcaaggcc cacatactca tcaaggttga
    60901 cactggttag atttgaaaaa tcaaggtcac tctcaacaat ttccttgtaa aattcaagtg
    60961 ggctacttcc tgtcgcaagt cctagagttt gagctccatt agccaatttt tccttcaaaa
    61021 tctcaaaagc aacttttcca ccttgaactt ggttttcaac tttaataact ttcatctttt
    61081 catcctccat ttctgtctat atttattata tggtatagac caatttttgt caagtgaaaa
    61141 cgatttaatt tctaaaaaaa gagcgtccaa acttgaaacg tgttataatg gataggatta
    61201 gaacttagaa agaatgaaca gatatatgaa tacagctgat tttgatttcc acttgccaga
    61261 ggaattgatt gcccaaacgc cccttgaaaa acgtgatgcc tccaaactcc tcatcgtcaa
    61321 ccgtgagaca ggagaaatgc aagataaaca cttccactct attattgata tgctggaacc
    61381 tggtgatgcc cttgtcatga acgacacccg agttctccct gcccgcctct atggtcaaaa
    61441 agtggagaca ggaggtcatg tggaacttct cctccttaag aacactagtg gagacgagtg
    61501 ggaagttctg gctaaacctg ccaaacgcct caaggtcggt actcgtatca gctttggtga
    61561 tggccgcctc agcgctgtcg ttacagaaga attgacccac gggggacgca ttgtccgctt
    61621 tgaataccaa ggaattttcc tagaagtctt ggaaagtctg ggagaaatgc ctctgccacc
    61681 ttatatccac gaaaaattag atgaccgtga acgttatcaa accgtctacg ccaaggaaag
    61741 cggctctgct gcagcaccga ctgctggtct tcacttcacc aaagaactgc tggcagaaat
    61801 ccaagctaag ggtgttcatc tagtctatct gactctccat gtcggactcg gaacctttag
    61861 acctgtttct gtggataatc tggacgaaca cgaaatgcac tcagagttct atcaactttc
    61921 tgaggaagct gctgccaccc ttcgctctgt caaaaaaaat ggtggtcgtg tcatcgctgt
    61981 cggaaccact tctatccgca ccttggaaac tattggttcc aagtttgatg ggcaaatcca
    62041 agcagattct ggttggacca atatctttat caaacctggg tatgagtgga aggtcgtgga
    62101 tgccttctca accaacttcc acctgccaaa atcaactctg gtcatgttgg tttctgcctt
    62161 tgcaggccgt gaattagtct tagatgccta ccaccattcc atccaagaac actaccgctt
    62221 cttcagtttt ggtgacgcca tgtttattta ttgagaaaga atttctctaa atcttctaat
    62281 accaataaat cgctaagata ttatttcaaa gaacatctac aattgaaact ctagctagct
    62341 gtagaagagg cctagtacat tgaaattaaa atgcttcccc ctagcttcga aaatattgcc
    62401 atagattgcg ttgactctcc aaattgattc atctatattt tatttcagct tcctatattt
    62461 tcttcgctgt ttgtaaatca aaatgcaaga cacatgagta gcaccatatt tgttactctt
    62521 atctgtcctc tcaagagact attatgagtt atttcagaat cattcactac tttgaccctg
    62581 actctcctta gtctcaaaat caaagactta tactcttcaa aaatctcttc aaaccgcgtc
    62641 aacgtcacct tggattatat atgtgactga cttcgtcagt tctatctaca acctcaaagc
    62701 agtactttga gcaacctgcg actagttttc tagtttgctc tttgattttc attgagtatt
    62761 aaacaaaaag tgaacaaatc tgaattctaa tgtacagaag actaggcttg ttcacttttt
    62821 tatagtcgct ataagatgac cttatctata gcttttt
//
LOCUS       DAVHSY010000009        53816 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.009, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000009 DAVHSY010000000
VERSION     DAVHSY010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53816
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.009"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(1..155)
                     /locus_tag="VVR43_000706"
                     /pseudo
     CDS             complement(1..155)
                     /locus_tag="VVR43_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            141..626
                     /locus_tag="VVR43_000707"
     CDS             141..626
                     /locus_tag="VVR43_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU6149102.1"
                     /translation="MAPTDKEDLIRTLELAPHIEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            710..1417
                     /locus_tag="VVR43_000708"
     CDS             710..1417
                     /locus_tag="VVR43_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6149103.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            1418..2749
                     /locus_tag="VVR43_000709"
     CDS             1418..2749
                     /locus_tag="VVR43_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU6149104.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            2916..3791
                     /locus_tag="VVR43_000710"
     CDS             2916..3791
                     /locus_tag="VVR43_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEU6149105.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            3909..4772
                     /gene="pstC"
                     /locus_tag="VVR43_000711"
     CDS             3909..4772
                     /gene="pstC"
                     /locus_tag="VVR43_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU6149106.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            4765..5580
                     /gene="pstA"
                     /locus_tag="VVR43_000712"
     CDS             4765..5580
                     /gene="pstA"
                     /locus_tag="VVR43_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU6149107.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            5582..6334
                     /gene="pstB"
                     /locus_tag="VVR43_000713"
     CDS             5582..6334
                     /gene="pstB"
                     /locus_tag="VVR43_000713"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU6149108.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            6349..6999
                     /gene="phoU"
                     /locus_tag="VVR43_000714"
     CDS             6349..6999
                     /gene="phoU"
                     /locus_tag="VVR43_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU6149109.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            7067..7492
                     /locus_tag="VVR43_000715"
     CDS             7067..7492
                     /locus_tag="VVR43_000715"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6149110.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(7666..8046)
                     /locus_tag="VVR43_000716"
     CDS             complement(7666..8046)
                     /locus_tag="VVR43_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6149111.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            8258..9274
                     /locus_tag="VVR43_000717"
     CDS             8258..9274
                     /locus_tag="VVR43_000717"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU6149112.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            9296..10195
                     /gene="galU"
                     /locus_tag="VVR43_000718"
     CDS             9296..10195
                     /gene="galU"
                     /locus_tag="VVR43_000718"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU6149113.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(10267..10944)
                     /locus_tag="VVR43_000719"
     CDS             complement(10267..10944)
                     /locus_tag="VVR43_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU6149114.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(10928..11467)
                     /locus_tag="VVR43_000720"
     CDS             complement(10928..11467)
                     /locus_tag="VVR43_000720"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU6149115.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            complement(11479..12609)
                     /locus_tag="VVR43_000721"
     CDS             complement(11479..12609)
                     /locus_tag="VVR43_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU6149116.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEAGAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGIAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            complement(12677..13375)
                     /gene="dapD"
                     /locus_tag="VVR43_000722"
     CDS             complement(12677..13375)
                     /gene="dapD"
                     /locus_tag="VVR43_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU6149117.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVKI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            complement(13605..14516)
                     /locus_tag="VVR43_000723"
     CDS             complement(13605..14516)
                     /locus_tag="VVR43_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU6149118.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            complement(14581..17046)
                     /locus_tag="VVR43_000724"
     CDS             complement(14581..17046)
                     /locus_tag="VVR43_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU6149119.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEVTQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            17188..18444
                     /locus_tag="VVR43_000725"
     CDS             17188..18444
                     /locus_tag="VVR43_000725"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU6149120.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(18522..20585)
                     /locus_tag="VVR43_000726"
     CDS             complement(18522..20585)
                     /locus_tag="VVR43_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU6149121.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIKLMKKSEENKKTKQRYFIKMADKVVKYNFFGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(20587..20865)
                     /locus_tag="VVR43_000727"
     CDS             complement(20587..20865)
                     /locus_tag="VVR43_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149122.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            21017..21865
                     /locus_tag="VVR43_000728"
     CDS             21017..21865
                     /locus_tag="VVR43_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU6149123.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQSASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            complement(23587..25845)
                     /gene="glgP"
                     /locus_tag="VVR43_000729"
     CDS             complement(23587..25845)
                     /gene="glgP"
                     /locus_tag="VVR43_000729"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEU6149124.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(25871..27388)
                     /gene="malQ"
                     /locus_tag="VVR43_000730"
     CDS             complement(25871..27388)
                     /gene="malQ"
                     /locus_tag="VVR43_000730"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU6149125.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            27938..29209
                     /locus_tag="VVR43_000731"
     CDS             27938..29209
                     /locus_tag="VVR43_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU6149126.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGTKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            29320..30612
                     /locus_tag="VVR43_000732"
     CDS             29320..30612
                     /locus_tag="VVR43_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6149127.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            30614..31456
                     /locus_tag="VVR43_000733"
     CDS             30614..31456
                     /locus_tag="VVR43_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6149128.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            31709..32509
                     /locus_tag="VVR43_000734"
     CDS             31709..32509
                     /locus_tag="VVR43_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU6149129.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTVSQASSVVIG
                     SSQIKELPKNLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            32519..33505
                     /locus_tag="VVR43_000735"
     CDS             32519..33505
                     /locus_tag="VVR43_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6149130.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            33572..33754
                     /locus_tag="VVR43_000736"
     CDS             33572..33754
                     /locus_tag="VVR43_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149131.1"
                     /translation="MRFNVGRFTSFSTEIESFPKIFLYSMKIKVQTRKLAAGCSKHCF
                     EVADRTDEVSNIYTAR"
     gene            complement(33796..34737)
                     /locus_tag="VVR43_000737"
     CDS             complement(33796..34737)
                     /locus_tag="VVR43_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU6149132.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(34715..36478)
                     /gene="aspS"
                     /locus_tag="VVR43_000738"
     CDS             complement(34715..36478)
                     /gene="aspS"
                     /locus_tag="VVR43_000738"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU6149133.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRVKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
     gene            complement(36714..36794)
                     /locus_tag="VVR43_000739"
                     /pseudo
     CDS             complement(36714..36794)
                     /locus_tag="VVR43_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(36830..37060)
                     /locus_tag="VVR43_000740"
     CDS             complement(36830..37060)
                     /locus_tag="VVR43_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149134.1"
                     /translation="MKRVILVAVIQAVVLFFIIGGLAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(37078..37719)
                     /locus_tag="VVR43_000741"
     CDS             complement(37078..37719)
                     /locus_tag="VVR43_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6149135.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLVLGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(37731..38465)
                     /locus_tag="VVR43_000742"
     CDS             complement(37731..38465)
                     /locus_tag="VVR43_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU6149136.1"
                     /translation="MKKKRRLLFLMSIVFGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(38468..38665)
                     /locus_tag="VVR43_000743"
     CDS             complement(38468..38665)
                     /locus_tag="VVR43_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149137.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(38665..38871)
                     /locus_tag="VVR43_000744"
     CDS             complement(38665..38871)
                     /locus_tag="VVR43_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6149138.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(38881..39195)
                     /locus_tag="VVR43_000745"
     CDS             complement(38881..39195)
                     /locus_tag="VVR43_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149139.1"
                     /translation="MWVLGFILFLIFFYSNDSKKIKKLEKKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(39417..39497)
                     /locus_tag="VVR43_000746"
                     /pseudo
     CDS             complement(39417..39497)
                     /locus_tag="VVR43_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(39488..40777)
                     /locus_tag="VVR43_000747"
     CDS             complement(39488..40777)
                     /locus_tag="VVR43_000747"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU6149140.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(40855..42102)
                     /locus_tag="VVR43_000748"
     CDS             complement(40855..42102)
                     /locus_tag="VVR43_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU6149141.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFWKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTVCFSLVAVWNIQLT
                     WMLFVGFSLLAIFLTILNLKNDI"
     gene            complement(42293..43144)
                     /gene="rgg"
                     /locus_tag="VVR43_000749"
     CDS             complement(42293..43144)
                     /gene="rgg"
                     /locus_tag="VVR43_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEU6149142.1"
                     /translation="MEQIGKVFRQLRESRNISLRQVTGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            43268..43609
                     /locus_tag="VVR43_000750"
     CDS             43268..43609
                     /locus_tag="VVR43_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU6149143.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            43667..43747
                     /locus_tag="VVR43_000751"
                     /pseudo
     CDS             43667..43747
                     /locus_tag="VVR43_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(43863..45566)
                     /gene="ilvD"
                     /locus_tag="VVR43_000752"
     CDS             complement(43863..45566)
                     /gene="ilvD"
                     /locus_tag="VVR43_000752"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU6149144.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(45799..46731)
                     /locus_tag="VVR43_000753"
     CDS             complement(45799..46731)
                     /locus_tag="VVR43_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU6149145.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSSSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFSSRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSSLCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(46728..47585)
                     /locus_tag="VVR43_000754"
     CDS             complement(46728..47585)
                     /locus_tag="VVR43_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU6149146.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(47589..48935)
                     /locus_tag="VVR43_000755"
     CDS             complement(47589..48935)
                     /locus_tag="VVR43_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU6149147.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(48948..49232)
                     /locus_tag="VVR43_000756"
     CDS             complement(48948..49232)
                     /locus_tag="VVR43_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6149148.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(49236..51266)
                     /locus_tag="VVR43_000757"
     CDS             complement(49236..51266)
                     /locus_tag="VVR43_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU6149149.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            51457..52464
                     /locus_tag="VVR43_000758"
     CDS             51457..52464
                     /locus_tag="VVR43_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU6149150.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            52467..52667
                     /locus_tag="VVR43_000759"
     CDS             52467..52667
                     /locus_tag="VVR43_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU6149151.1"
                     /translation="MSEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            52819..53001
                     /gene="rpmF"
                     /locus_tag="VVR43_000760"
     CDS             52819..53001
                     /gene="rpmF"
                     /locus_tag="VVR43_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU6149152.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            53017..53166
                     /gene="rpmG"
                     /locus_tag="VVR43_000761"
     CDS             53017..53166
                     /gene="rpmG"
                     /locus_tag="VVR43_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU6149153.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(53646..>53816)
                     /locus_tag="VVR43_000762"
     CDS             complement(53646..>53816)
                     /locus_tag="VVR43_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149154.1"
                     /translation="VKDKGLWYYLNESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPD
                     GYRVNANGEWVG"
BASE COUNT        16573 a        11553 c         9890 g        15800 t
ORIGIN      
        1 ttttaccaga ataattcgct aattcttttt ttagggcgat tgatttgtac ttccgtcgca
       61 tcaatcatta ccgtgtcctc agaactgaga ggagttcttg aaatcgtaaa accactttga
      121 acaagagtta cttcaaccca ttggctccga cggataaaga agacttgata agaactctag
      181 agttagctcc ccatattgaa ggtggctatt ttagacaaac aaaaaaagct tcagacacta
      241 taaaccttgc tggtaaggga agggcgcttt ataccagtat ttatttctta ttagaagaaa
      301 cgaatccttc acattttcac cgattgacag cagatgaaat ctggtatttt catgcaggat
      361 ccccacttac tgttcacatg attacagcag atggtcacta cgaagcagtc actttaggcc
      421 tggacatatc caaagggcaa caacttcact actgtgttcc taagggcact atttggggat
      481 caacagttga taaggatgat gctctggttt cttgtcttgt tgctcctggt tttgaatttg
      541 aggattttga attatttgaa agggtagatc tactggcgac ctatccagag cacaaggaga
      601 tgattgagcg tttgaccaga tactagtctt gataggcaaa tttaatctga tttagcaatg
      661 ttaggatttc tgataattgt gttataatgt taccaatagg agataataga tgacaaaaca
      721 agtcttatta gtggatgatg aagaacacat tctgaaattg cttgactacc atttaagtaa
      781 ggaaggcttt tctactcaat tggtgacaaa tggacggaag gccttagctt tggcagaaac
      841 agaacccttt gattttatct tgcttgatat catgttacca caattagatg gcatggaagt
      901 ttgtaagcgg ctgagagcca aaggcgtcaa aactccaatt atgatggttt ctgcgaaaag
      961 tgatgaattt gataaggttt tggccttgga attaggggct gatgactacc tgaccaagcc
     1021 ttttagccct agagaattgc tggcgcgtgt caaggctgtc ctcaggcgaa ctaaaggaga
     1081 acaagaagga gatgattcag ataatatcgc tgacgattct tggctatttg ggaccttgaa
     1141 agtataccct gagcgtcatg aagtctacaa ggcgaataag ttactgagtt tgaccccaaa
     1201 agaatttgaa ctcttgctct atcttatgaa acatcccaac atgacactga ctagagagcg
     1261 tcttttggaa cgtatctggg ggtatgactt tgggcaggaa acacgtttgg tggacgttca
     1321 tattggtaag ttgagggaaa aaattgaaga caatcctaaa gcccctcaat ttattcgaac
     1381 cattcggggt tatggttata agttcaagga gttatagatg aaacgctacc ttcaattttg
     1441 gctagtcaat ctaagtgtta gcctcattct gattgcaggg atggcattaa cttggatcag
     1501 taaaggcatc ggtctctttc ttctagccct ttctttggga ctaggtggct actggctctt
     1561 ttgcctttgg aaatgggaag ttgcttttga gaccttgcac caacctctct tgaccagtag
     1621 tgaatacttt ttagaaaaag ggcaagaaga cttaaagtct ttggctcagt atgtgtctgg
     1681 cctaaaaacc aaagtctccc aacaggatca gcaatacaag gatctagccg aaacaatgga
     1741 ggttcttctg tcgcacctaa ccatggggac gtttttagtt tccgctcaag gtcagatgtt
     1801 attatccagt cgctctctgc ctcattattt tcccgatgtg gacggcgaca taagttcact
     1861 tgatgacctc aaacggatgg atattcggaa tttagttcac caagcctttg atcaaaaaac
     1921 aaggttaaaa caagaagtaa gtgggtttca tgagggtgac ttgattttag aagtgacagc
     1981 agttcccgtt tttagcccca cccaatctgt ggaagctgtg ctcgtcttgc tatatgattt
     2041 aacaacgatt agaacttatg aaaagttaaa tttagccttt gtctcaaatg cctcccatga
     2101 attgaggaca ccagttactt cgattaaggg ctttgctgaa accattaagg ggatgtcagc
     2161 tgaagaagaa gcgctcaagg atgactttct agacattatt tacaaagaaa gtttgcgtct
     2221 tgagcatatt gttgagcatc ttcttacctt atctaaggct caacaaatgc ctatacaatg
     2281 gacgaccctt tctttggcag aatttgtaca ggatttgact caaagcttgc aacctcagct
     2341 caagaagaag gatttacagc taaaggtgca ggtgccagat gatgtcaccc tcgtatcaga
     2401 tagtcaatta ctttcccaaa tcttactcaa tcttttatcc aatgccatcc gttacactga
     2461 acaaggggga aaaattgagg tcaagaccca aaaggtgaac gaaggcatta agatttctgt
     2521 atcagataca gggattggta ttagtcaatt agagcaggat cgtatttttg aacgttttta
     2581 ccgagttaat aaaggtcgaa gcagacaaac tggtggcact ggtcttggcc ttgccattgt
     2641 caaagaactc agtcaattat taggtggcca agtcacggtg acgagtcagc ttggcagagg
     2701 cagttgcttc acgatttttc ttcctaacca atctttcgca caggactaat aatttttaaa
     2761 gctattttta ggagcagcca tttttcaaaa gtggcttttt ttgattcttt acacaatctt
     2821 tacatgaatc agggataaac ctttacaaag acttgttaga ctataaatgt agtaagccta
     2881 cacaagaaaa atacatagag ataaaggtga ttattatgaa attcaaaaaa atgcttactc
     2941 ttgcagccat tggcttatca ggatttgggc ttgttgcctg tggcaatcag tcagctgctt
     3001 ccaaacagtc agcttcagga acgattgagg tgatttcacg agaaaatggc tctggaacac
     3061 ggggtgcctt cacagaaatc acagggattc tcaaaaaaga cggtgataaa aaaattgaca
     3121 acactgccaa aacagctgtg attcaaaata gtacagaagg tgttctctca gcagttcaag
     3181 ggaatgctaa tgctatcggc tacatctcct tgggatcttt aacaaaatct gtcaaggctt
     3241 tagagattga tggtgtcaag gctagtcgag acacagtttt agatggtgaa taccctcttc
     3301 aacgtccctt caacattgtt tggtcttcta atctttccaa gctaggtcaa gattttatca
     3361 gctttatcca ctccaaacaa ggtcaacaag tggtcacaga taataaattt attgaagcta
     3421 aaaccgaaac cacagaatat acaagccaac acttatcagg caagttgtct gttgtaggtt
     3481 ccacttcagt atcttcttta atggaaaaat tagcagaagc ttataaaaaa gaaaatccag
     3541 aagttacgat tgatattacc tctaatgggt cttcagcagg tattaccgct gttaaggaga
     3601 aaaccgctga tattggtatg gtttctaggg aattaactcc tgaagaaggt aagagtctca
     3661 cccatgatgc tattgcttta gacggtattg ctgttgtggt caataatgac aataaggcaa
     3721 gccaagtcag tatggctgaa cttgcagacg tttttagtgg caaattaacc acctgggaca
     3781 agattaaata aaatgtttgc tccataaatc tctaaagaga tgcagacgtt tcatcgtaca
     3841 ataagataaa gaaggcaagt agggaggtgt cgtatctccc ttactttctt cactagaaag
     3901 gacaagatgt gataaaacaa gccttcaaag aagcagtttt tagggcaatt tttttcatga
     3961 gtgcaacagt agctgttgta gctattttgc taatctgttt ctttattttt agtaatggct
     4021 tacctttcat ggctaactac ggctttgccc gttttttatt aggcagtgat tggtcgccaa
     4081 cgaacattcc ggcaagctat ggtattttac caatgatcgt tggttcctta ttaattacct
     4141 taggagcgat tgtgattggg gtgccaacag gcatcttgac atcggtgttt atggtttatt
     4201 attgtccaaa gcccgtctat ggcttcttaa aatcagctat caacttgatg gcggccattc
     4261 catctattgt ttatggtttt ttcggcctac aattattggt gccttggatt agaacctttt
     4321 taggaaatgg catgagtgtc ctaaccgctt cgttactatt aggaataatg attttgccaa
     4381 ccattatcag tttgtcagaa tctgctatcc gaacagttcc caaaacgtat tattctggta
     4441 gcttggctct aggagctagt catgaacgga gtatttttag tgtcatcttg ccagctgcga
     4501 gatctggtat tttatcagca gttattttag gaatcggtcg cgcagtaggt gaaaccatgg
     4561 cagttatttt ggtggcaggc aaccagccga ttattccaag tggactcttt tcaggaacca
     4621 gaaccttaac aaccaatatt gttctggaaa tggcttacgc atcaggtcag catagggaag
     4681 cccttattgc aacctcagca gttctctttt tccttattct cttgattaat gcctactttg
     4741 cctacttgaa aggaaaatca tcttatgagt aaatacctgc taaaacttct cgtttattgt
     4801 ttttcagctt taacctttgg ctctctcttt ttaatcattg gttttatcct catcaaaggc
     4861 ttacctcatc taagtctatc cctcttttct tggacttata cttctgagaa catttccctt
     4921 atgccagcga ttatttccac cgttattctg gtttttggtg ctcttctttt agccttgccc
     4981 atagggattt ttgctggttt ttatcttgtg gaatatacaa aaaaagattc cctttgtgtt
     5041 aaaatcatgc gattggcctc agataccttg tctgggattc cttccattgt ttttggtctg
     5101 tttggcatgc tcttctttgt agtcttctta ggttttcaat actctctgtt atcaggaatc
     5161 ttaacctcag ttatcatggt gttgccagtc attattcgct caacagaaga agccctttta
     5221 tctgttagtg atagcatgcg tcaagcaagt tatggacttg gggcaggtaa gttacggact
     5281 gtttttagaa ttgttctacc agttgccatg ccaggtattt tagctggagt gatactagct
     5341 attggccgta tcgttggtga aacagctgcc ctcatgtata cattaggtac ctctaccaat
     5401 acgccaagta gtctcatgtc ttcaggccgt tctctagccc tacatatgta tatgctgtca
     5461 agtgaggggc tacatgtcaa tgaagcctat gctaccggcg tgattttgat tattactgtt
     5521 ttaatgataa atactctatc aagcttatta tctcggaaac ttgtgaaagg agcttcctag
     5581 tatgggaaca ttttcagtta gacacctaga tttattttac ggggattttc aagccttaaa
     5641 aaatatttcg attcaattac cagaaagaca gattactgcc ttgataggcc catctggttg
     5701 tggcaaatca acttttctaa aaacccttaa tcggatgaac gatttggttc cttcttgcca
     5761 tattgaaggc caagtcctct tagatgagca agatatttat agtagcaaat tcaaccttaa
     5821 tcagctacgc aagcgtgtag ggatggtttt tcaacagcct aatccctttg ccatgtctat
     5881 ctatgataac gtggcttatg gtccaaggac acatggtatt cgagacaaaa aacaattaga
     5941 tgccttagtg gagaaatctt taaaaggggc agccatttgg gaagaagtca aagatgatct
     6001 taaaaagagt gccatgtcct tatctggcgg tcagcagcaa cgcctttgca ttgcgcgagc
     6061 tttagcagta gaacctgatg ttctgttaat ggatgagccg acttcagcct tagaccctat
     6121 ctccacttta aaaattgaag acctcattca gcaactaaaa aaggattata cgattatcat
     6181 tgttacccat aacatgcaac aagcttcacg tatttcagat aaaactgctt ttttcttaac
     6241 aggagaaatt tgcgaatttg gagataccgt tgacgtgttt accaatccaa aagatcagcg
     6301 cacagaagac tatatttcag gacggttcgg ataaggaagg aaaaacctat gagaaatcaa
     6361 tttgacttag aattgcatga attagaacaa tcctttttag gactagggca acttgtcctt
     6421 gaaacagctt caaaagcctt actggcctta gcctccaaag acaaggagat ggcagagcta
     6481 attatcaata aggatcatgc tatcaaccaa ggtcaaagcg ctatcgaatt gacctgtgcc
     6541 cgtttgttgg ccttgcagca gccacaagtg tctgaccttc gatttgtaat tagcatcatg
     6601 tcttcttgtt cagaccttga acgtatggga gaccatatgg caggcattgc caaagctgtt
     6661 ttgcaactaa aagaaaatca actagcccct gacgaagaac agttacacca aatgggtaaa
     6721 ttatccctca gcatgctagc cgatttattg gttgcctttc ctttgcacca agcctcaaaa
     6781 gctattagta ttgctcaaaa agatgaacag attgaccaat attattatgc cttatcaaag
     6841 gaaatcattg gacttatgaa agaccaagaa acctcaattc ccaatggaac tcaatacctt
     6901 tatatcatag ggcatctgga acgcttcgct gattacattg ctaacatttg tgaacgccta
     6961 gtctacctag aaacaggaga actagtggat ttgaattaat tcaactaatc cttaaaagag
     7021 aagagtacga ttaagtgctc ttttttatgg ttgtaaaaaa gttcatttga ccaatttaag
     7081 cagtgtagat agtgaggagc tgtttcaatt ctatcgtgaa cgagggaatg ctgaaaactt
     7141 tatcaaagaa aggaaagcag gattctttgg ggataagaca gatagttcga ccatgattaa
     7201 gaatgaagta cgtatgatga tgggctgtct ggcttataat ctctacctct ttttaaagca
     7261 gctagctggt gatgaagtaa aggccttgac tatcaagcgt tttcgacgtc tcttccttca
     7321 tattgccgga aaatatgtct ctactgctag acgacatatt ctcaaattct caagtctata
     7381 cgcctattca aaacagtttc aagccttatt tgatacaatc tgccagataa atctgatact
     7441 ccctgttcca tatagagcta gagggcaggg gaaaacatgc ctaacagaat aagtcacctt
     7501 attttaaaaa tcgagcatca aaccaaggga ggagtctgcc cttttttagg aaaaaatcaa
     7561 gacaaatctc ctcaattatg tctcgaacat cagaaattaa gcaaaatcac cagaaggaca
     7621 gtatttcaac tagcttttct ggtaattttt gaactgtgta gttcgttagt gccagatatg
     7681 aataatttgg gatgataaat ctttcttcct caggtagcct atcataatac tcttcaaaaa
     7741 tcttatcaaa acactctctt tcttttgggc gatagtttca tcttcgtatg taggagtcct
     7801 catcaagaaa tacttcaatt ctaggtattc cttatccaac tctatataac ttggcatcaa
     7861 cttgtaatct tcaaccccca aacgttcagc gatatatttt aactttgtta gtgttggtct
     7921 ggattctcca ttttcaattc taattaattg acggatactt aattcagact catcaccaca
     7981 aaattctgaa cgactgattt ttttagccaa acgtaatctt ttaatttttt cgccaaactc
     8041 tcgcaaccta caagaacctc ctgagttgtt tacctctatt tatagcatat actgaatcaa
     8101 actatctatc agatttcttc tcactttaac taaagactaa gagtttatcc cttcatctcg
     8161 gtttttgtgt atttttccac cataccccag taatgcaagt gcaaaatccc ctagaatatg
     8221 atagaataag agaaagaact ctatcaagga ggaaatcatg gaaaaacaaa ccgtcgccgt
     8281 cttggggcct ggttcttggg gaaccgccct ttcacaagtc ttaaatgaca atggacacga
     8341 ggtacgtatt tggggaaatc ttcccgagca aatcaatgaa attaatacac accatactaa
     8401 taagcactac tttaaagatg tcgttctaga cgaaaatatc attgcctaca ccgacttagc
     8461 agaaacattg aaagatgtgg atgcgatttt gtttgttgtc ccaacaaaag tgacacgact
     8521 tgttgcccag caagttgcac aaaccttgga ccataaggtt atcatcatgc acgcatcaaa
     8581 gggattagaa cctgatagcc ataaacgatt atcaaccatt cttgaagaag aaattcctga
     8641 acatctccgt agtgatatcg tcgttgtttc agggcctagt catgcagaag agaccattgt
     8701 gcgtgaccta actttaataa ctgctgcttc taaagattta caaacagctc aatacgttca
     8761 gaagctattt agtaatcact acttccgact ttataccaat acggatgtta tcggggttga
     8821 aactgctggt gctcttaaaa atattattgc tgtcggtgct ggagctttac atggtcttgg
     8881 atttggtgat aatgctaagg cagccatcat cgctcgaggt ttagcagaaa tcacccgcct
     8941 aggggtagca ctcggggcca gtccattgac ctatagcggc ttatctggtg tgggagattt
     9001 gatcgtaacg ggaacttcca tccactctcg taactggaga gctggagatg ctctcggacg
     9061 aggagaatcc ctagctgata tagaagctaa tatgggcatg gtaatcgaag gaatttcaac
     9121 gactcgagca gcctatgaac tagcccaaga acttggagtc tatatgccca ttacacaggc
     9181 tatttaccaa gttatttatc acggaaccaa tatcaaagat gccatttatg acatcatgaa
     9241 caatgaattt aaagcagaaa atgagtggtc ttaaccctct atagaaagga tttttatgac
     9301 atcaaaagtt agaaaggcag tcatccctgc tgctggacta ggaactcgat ttttaccagc
     9361 aaccaaggcc cttgccaaag aaatgttgcc aatcgtagac aaaccaacta tccagtttat
     9421 cgtggaagag gctctcaaat caggtattga agatattcta gttgtcactg gtaaatcaaa
     9481 acgttctatt gaggaccact ttgattcaaa cttcgaattg gaatataacc tcaaagaaaa
     9541 agggaaaaca gatcttttga agctagttga taaaacaact gacatgcgtc tgcattttat
     9601 ccgccaaact catccacgcg gtctcggaga tgctgttttg caagccaagg ctttcgtcgg
     9661 aaatgaacct tttgtcgtta tgcttggtga tgacttgatg gatatcacag acgaaaaggc
     9721 tgttccactt accaaacaac tcatggatga ctacgagcgt acccacgcgt ctactatcgc
     9781 tgtcatgcca gtccctcatg acgaagtatc tgcttacggg gttattgctc cgcaaggcga
     9841 aggaaaagat ggtctttaca gtgttgaaac ctttgttgaa aaaccagctc cagaggacgc
     9901 tcctagcgac cttgctatta tcggacgcta cctcctcacg cctgaaattt tccaaatcct
     9961 cgaaaaccaa gctccaggtg caggaaatga aattcagctg acagatgcaa tcgacaccct
    10021 caataaaaca caacgtgtat ttgctcgtga gttcaatggg gctcgttacg atgtcggaga
    10081 caagtttggc ttcatgaaaa catccatcga ctacgccctc aaacacccac aagtcaaaga
    10141 tgatttgaag aattacctca tccaacttgg aaaagaattg actgagaagg aataaaataa
    10201 aataaaaaga taaggttcaa aaaatgcctt atcttttttc attacacaaa ttttctttca
    10261 acttcgtcac attcccattc ccttgtagaa aagcaaaatg gcgagtccta cgaacaagac
    10321 taccgctcct aatctctggc tggtattata catccgtttt tctcctctaa ctggaaagat
    10381 aactgctaga aatgcgccac caactgcacc accgatatgg cctgctaggc tgattcctgg
    10441 aatcagaaca cttccaataa tgttaaccac aaaaagtgtc agataggatt gccctagctg
    10501 ttggatataa ggattgcgag ttgcatagcg aagaacaata atcgcggcaa atagcccata
    10561 aagagaggta gaggcgcctg ctgctaagga tttaggacta aatacaaaaa caaagagatt
    10621 gcccatcatt cctgataaga gatagagaaa aaagaactgc ttagagccga aaatctcctc
    10681 tacctgcctt ccaagataat aaagtgaaag catattaaca atgaaatgtt cccacccaat
    10741 atgaacaaaa atggcagaca agagacgcca aacctgctcg ggaaagaggc gaatagctgg
    10801 cccatacatg gctccaaatc gaaataatgt atctgccctg tcaaagtttc cgcctgcagt
    10861 gaccaacatt agtaaaaata ccaaggccgt cactaagagg aagaaactcg tcacagggta
    10921 acgtctatca aagatttcct tcatcaatta atacctcctg aacaggaata tcatggtttt
    10981 caggtataaa gtcctgaatt tgacaaggat gaaccgtact caaagtatga ccagaaaaat
    11041 gttccagata gcggtcataa taacctccac catatccaat ccgatatcca tccgtcgtaa
    11101 aagccaggcc aggaacatga atcaaatcaa tctgagatac atccaccact tccaaatctc
    11161 cctgtggctc cagtaaggca aaggcagttt ttaccaactg ctgcggatca tagactacaa
    11221 agtccatgcg ccccttggga taagttttgg gtattaaaac cttcttgccg tccttcagcg
    11281 cctgctcaat cagttcccgc gtttgaaact catgagaaaa agagaggtag gttgcgatga
    11341 ccttggcttc ttgataaaag gggtgttgta aaattcgctc ggttaaagct tggtctatag
    11401 cctgtttttg ttcttgagat aaagccttca tttcatgcaa gacttgcttg cgtaattccg
    11461 atttcataga caagccctct attctgctgc cttctttttc aggaaactag acaccgcagc
    11521 caccccaata gctaagactt cttccttagg actcatttga gggtgatgaa gagcgtaggg
    11581 actatcgata cctagccaaa acatcacgcc atcaaccttt gaaaggagat aaccaaagtc
    11641 ctcgcctgtc atagcaggtt cgatatcaat caactcgatt ccgtcttttt cgtcaaagaa
    11701 gtccatcagt tcacgcgcca aggctggatt gttctcaaca ggtaggtatc caccttgttt
    11761 gagttccact tcgacttcca tatcaaaggc agctgcaatc ccttctgcaa ctgtttttac
    11821 cctcttttgc accaagagac tcatgtcctg tgtcaaggca cgaatagttc catgtaaaaa
    11881 agctgtgtct gtgatgacat tgttggtggt tccagcttga aaaacgccga aagtcaccac
    11941 tgctccctcg attgggttta cattgcggct aacaactgac tgcacttggg tcacaaagta
    12001 actagccgcc accaaggcgt cattggcttc atgaggaaaa gccgcgtggc cacctttacc
    12061 tttgaaacgg atcttcacct cgcaagttcc tgcaaagagt gtatgagtat tagtcgcaat
    12121 ctggccgact ttcaaatctg gacggacatg gaggccataa aattgatctg gcaaccaatc
    12181 tccaaaagca ccagcctcat acatgagcat accaccagct tcattttctt cagcaggctg
    12241 aaatagaaag agcagattat ttttaggttg ctcctcaagg gcgcgctcaa gacagcctaa
    12301 ggcaatggtc atatgaaaat catggccaca ggcatgcatg cgaccttggt gttgagaagc
    12361 aaaaggtaga cctgtttgtt cgacgatagg caggccatca atatctgtcc gccaaccaat
    12421 ggttcgctcc ggctgacttc cctgcaggta gaccaaaatc cctgtccgcc aagtacgaat
    12481 ttgaacaaaa tccttgcccg tagtcaattt ctcaatcaca tccagcaaat aagcctgagt
    12541 cttgaactcc tccaagccaa tctctggaat ctggtgtaaa tctcgtctag tctgaatcaa
    12601 atctaacatc tatctgtcct ccgatatagc agaaagaggc tggaaaaagg gttccgcctc
    12661 ttttttactt ttacaattac aaggtacgaa gcgcatcctc taacgctgtt ttttgttgag
    12721 tttgggcatc aatttctttg ataatacgag ctggaacacc tgctactacc acgttttctg
    12781 ggacatcttg ggtaacaata gctcctgctg cgacaactga accactaccg atttggactc
    12841 cttcgataac cactgcatta gccccgataa gaacattgtc tccgacacgg actggttcag
    12901 cactagctgg ctcaatcaca cctgccaaaa ctgcacctgc accaacgtgg ctattttttc
    12961 caacgatagc acggccacca aggatggcac ccatgtcaat catggttcca gcaccgattt
    13021 cagcaccgat attgataaca gctcccatca tgataacagc attgtcacca attttcacct
    13081 ggtcacggat aatagcacct ggctcgatac gagcgttgat agcacgctta tctagcaaag
    13141 gaactgcaga attacgagca tcttgctcga caacataatc ttgattttct accaaacctt
    13201 caagaagcgg agccacgtcc ttccagtctc cgaataggac atttcctagt ttgacaacag
    13261 agctaggcac agcagttgcg agttgcccct caaaggttac tttgacactg gttttctttt
    13321 cagcattggc gataaattgg ataatttctt gagcgttcat ttttgtagca gtcataggtg
    13381 cctcctggtt cgttataatg atacctattc taccaaaaaa ggcctcaaat ttgaaacctt
    13441 tttgtctgtt tttaggtatg attttttagg gatgtgagat aaaacgtgct gtcggtaaaa
    13501 gcaagcccct accgatacaa cctaaaaaca ctcttcacaa ctatctcccc gtgttttatt
    13561 gactattcta gtatagcaca cttttagaat taagaaaaga ctttttatct actttctttc
    13621 gcttcttcta tagacaaaaa tatcatgggt aaaataatca aggctatagc tagaaggagg
    13681 gaccaatcca ctactaatcc taagaacaaa acactcaaga gagcagaaga gagaggttca
    13741 ctggcactga taacggcaac caccaaagga gaaaccaagg acacagcctt catggaaatg
    13801 aaaaaagcaa aagccgttcc aaagaaagcg ataatgaggc aaatcaagat actccaaata
    13861 tcaagagtaa aggaaagctg ataaaccggc gagaggacat tgctaaacaa acctgccaaa
    13921 atcatccccc acccaaccgt aggaacaaaa ccataacgct tagcaaaagg ttggggcaag
    13981 ataacattaa acataacacc catggcactc agcaaacctg ttataagagc tagcggcgtc
    14041 atggataact gagagagatc tccctttgtc gccatcaagc aaacacccag catggcaacc
    14101 aaaacataga aaacagcgct ttttgacgct cgtttttgat aaaccaagcg attgtaaaag
    14161 aggataaaaa cagggctaat aaactgtaaa atagttgctg tcgtagcatt tgagtattct
    14221 acacagagat agaaaaaata ctgaactgaa aaaatcccca aaatagcata ggctaaaaag
    14281 ggcaggtaat ttttcttgtc tcgccaaata tctagcactt gcgattttaa ttgtattgca
    14341 gaccaaatga gtacaagact ccctgccagt gtcaaacgca tagaggtaat ccagcccgaa
    14401 gacacctgat aatgagtaaa gaagtactct cctaaaattc cacagattcc ccatattaag
    14461 ccggatagga gcgaataaat ttttccgtta acaatctttt tctgatactg attcataccc
    14521 ttattgtaac acgaaaggaa aaaagtggca atccattgat tggccacttc atttagagaa
    14581 ttatcgtctc gcccttgaag aagaaggtcg tgtagtactt gagttactgc tatcgctaga
    14641 actactactt gaactgctgg agctggatgg agttggtaga ctccccacaa tactagacca
    14701 agcattctga taatccgcat cacttccgcc aatagcaaag cgataacttg tcgctggcgc
    14761 tcctgactta ttagcccaat agctggtaac agtcgaacct gtgacctcta cttcttttcc
    14821 ttcaacagaa accttccctg gtttttgacc tgttgatttc aagacttccg atttcactac
    14881 actaggatct aaagcaaagc gctcgttccc ccaaatgctt ggggaagctt gctgaatcgc
    14941 atttaccaga tgagccatgt aattagagtt attagaataa cctgctctac gtgacaatga
    15001 atgattatca tcatgcccaa tccagccacc tagggttaat ctaggtgtcg aaagcatgag
    15061 ccacatattt tcgtcttggt tggttgtacc agtcttccca atccaatctg cattagccag
    15121 agtaggattt aaagaagtca ggttagactt gaaggttgtt gtcacacgag aggatagaac
    15181 ttctcgtagc aatccctgca taatcgtcgc agtagctttt gaatagactt gaaccggttt
    15241 atcctgatac tcatacacca ctctaccatc tgctgcttca atctttgaaa tcacatgctt
    15301 ctgatgataa actccattat tagctaaggt ctgatagcca ttggtatgct gggcaactgt
    15361 gacttcaata ccaccaccca ttggcaagct ctcaataccg tactcaggaa tctcgtaacc
    15421 catcttttcc atataaccct tgacatcaac acccttttca cggagcatac gataggtcca
    15481 gtaagcaggg atattccatg aatagttcag agcttctccc aaggtcatca ttcctgttcc
    15541 cttgctatta gcatacataa tcggattgcc attagcaaag tttgttggat agttagatag
    15601 aatcgtttca cttcccatca agccctggtc aatagcaata ccgtaggcca gcaagggctt
    15661 ggtagtagaa gctggcgaac gtttggtatc aaaggcatga ttattttgat tttcttgata
    15721 attacgacca cctacaaagc ctagaatagc acctgtttgg ttgtccatca agacattccc
    15781 tacttctaca cgacctgttc catcgtctaa aagatagcca taatcagcaa ccgcactttg
    15841 catggcagaa tgaattttct gatctatggt agtagtaatc ttataaccac cattttcaat
    15901 ttccttggct gccaaatctc gataaaactt ctgagttacc tcatttttca actccttagc
    15961 ggagacattg tctctctgag ctagatagtc atacatacgt tcttgagctt ctgccaaagt
    16021 tgtaaagtat aaatagtctc gtgaaattcc tgtaaccgtg cccgatggta aaaagtcctg
    16081 tttaaggtca taatccttgt actgagaata ctcgtctttg cttaatgcac ctgtacgata
    16141 catactgtaa agaactgcct tagcccgtct taagccaatt tctaggtctt catcactctt
    16201 caactcccca gtattttcat aaggagagta agtaatggga ctctgtggaa gtcctgctaa
    16261 aaatgctgct tgaggaacag tcaactgact ggcatctaca ccgaaaattc cctcagctgc
    16321 ttgccgagcc cctgcaatat tctgtccctt attatttcgg ccaaagggag ccacattgag
    16381 ataggtcgtt aaaatctcat ctttattcat ggcgcgttcc aaggcaagag catccacaat
    16441 ctctgccgcc ttacgagcca aggtcggcgc atccccaaca acctgctgtt taattagttg
    16501 ctgggtcaag gttgaacccc cactagagga acccaaacct acaaatttcc ccaaggtcgc
    16561 acgaatcacc gccttgggta ctacaccctt atgttcttta aagtgttcat cttctgtcgc
    16621 aatgatagcc ttcttcagat tttccgaaat ttgctcagat gagatagaag tgcgcaacaa
    16681 atcactctct atggaagcaa tcaccgtccc gtccgaatag gtaatctctg aaatagaaga
    16741 gatgtccttg acctgattca ccaattcttc tgtctgaggc acccgaacct tgtcaaataa
    16801 ggccactccg taccccaaag caatcccaac tcccaacatt cctcctagaa aaccgagtac
    16861 aaagagtaaa ttaaataagg cttttatact cagtaaaata gctgggaaaa tggctgactt
    16921 atctaaggtt ttagattttt tggtacttga acctttcttg ccaggtctag ctgatttttt
    16981 atttttttgt ttttgctgga aaaattccag catttttcgt tttaattcat ttaattgatt
    17041 ttgcatggat ttcctcactt tatctattat accacaaaag ggaaattttc aataaaatag
    17101 ccactttctt ccctattctg ctaggctatt gcccaagttt gtgatacaat aggtagaaac
    17161 aataatttta aaaaggagaa aagacacatg cacatttttg atgagctaaa agagcgtggt
    17221 ttgatatttc aaacgactga tgaagaagct ttgcgtaaag ccctagaaga aggtcaagtt
    17281 tcttattata ctggctacga tccaactgct gacagccttc acctaggcca ccttgtcgca
    17341 atcttgacaa gtcgtcgctt gcaactagca ggtcacaaac cttatgcgct cgttggcggt
    17401 gctacaggtc tcatcggaga tccgtccttc aaagatgctg aacgtagtct ccaaacaaaa
    17461 gacacagtag atggctgggt caagtctatc caaggacaac tttctcgttt tcttgacttt
    17521 gaaaatggcg aaaacaaggc tgtcatggtc aacaactacg actggtttgg cagcatcagc
    17581 ttcattgact tcctccgtga tattggaaaa tacttcacgg tcaactacat gatgagtaag
    17641 gaatctgtta aaaaacggat cgaaacagga atttcttaca ctgagttcgc ttaccaaatc
    17701 atgcaagggt acgacttctt cgtccttaac caagaccata atgtcactct tcaaatcggt
    17761 ggttctgacc agtggggaaa tatgacagct ggtaccgaat tgcttcgtcg taaggcggac
    17821 aagactggtc acgttatcac tgttccacta atcacagatg caactggtaa gaaatttggt
    17881 aaatcagaag gaaatgccgt ctggctcaat cccgaaaaga cttctccata cgaaatgtac
    17941 caattctgga tgaacgtgat ggacgctgac gctgttcgct tcttgaaaat ctttactttc
    18001 ttgtcacttg atgagattga agatattcgt aaacaatttg aagcagcgcc acacgaacgc
    18061 ttggctcaaa aagtcttggc tcgtgaagtt gttacacttg ttcacggaga agaagcctac
    18121 aaagaagcac ttaacatcac tgagcaactc tttgcaggaa acatcaaaaa cctttctgtc
    18181 aaagaactca aacaaggact tcgtggtgtg ccaaactacc aagtacaggc agacgaacac
    18241 aacaatatcg tggaactgct cgtctcatct ggtatagtta actcaaaacg ccaagcccgt
    18301 gaagacgtcc aaaacggagc catctacgta aacggcgacc gcatccaaga ccttgactat
    18361 gtcttgagtg acgctgataa gttagagaat gaactgactg ttatccgtcg tgggaagaaa
    18421 aaatactttg tattgactta ctaaactatt caacatttat ctataaacaa aggagttaac
    18481 ctcgagaaag gtaactcctt tttgctgtta ataactctca tctatctatt tttaatagac
    18541 aggctacgca ggacaatgcg caaggttgtt agattatgta agatagagag atttgaagga
    18601 ctgagccaat taaataagcc gaagccaatc aaactactat ttacgacaac ggtatcttga
    18661 atatttttct tgatgagtgt ttgcaaagat gatgataacg aatccaactc ttggaagaaa
    18721 tccaaacgat tatctaacaa taagatatca ctcatctgct tagaaatatc tgcactctca
    18781 ttcatcacca caccgatatc tgatagagtt aaagccgctg agtcattcaa tccatctcca
    18841 accatcaaaa tagtgtgacc tgctttctgc agtttctcta ctaactcaaa tttcccatca
    18901 ggtttcaagt ctgtatagac ctgatcaaag ggcaaatctt tgactaattc ctctgtccta
    18961 atcaaggtgt ctcctgttgc cagaatcaat tttttcccct gtgccttaag tttatccaag
    19021 gctgtttttg cttcttttct caaaggagta tgaatgcaga acattccaat caattcattt
    19081 tgataagcca agaataagag attgtagtga ctcttgtact cttcaattaa agcattttgt
    19141 tctgaactga tatgaatctg ctcatcctgc atcaagacat aattcccaat aagaactggt
    19201 tggccatcta tatgagattt gatccccttg cttgcgatat attggagttt cccatgcatt
    19261 tcctcatgtt caattccctc tatctcagct tgcttgacga tggcattagc aataggatga
    19321 taaatgtgtt cctcaagaca ggcactgatt ctgagaatat cttcctcact atagtctcca
    19381 aaaggtaaca ccttttcaac tataggataa ctagttgtga ttgttcctgt cttatcaaac
    19441 aagaaagtat caacttccag atatttctcc agaacatctc catccttaat caccatttca
    19501 cggttcaacc cttccttgat aactgtcaaa taagctacag gagtagagat tttcaaagcg
    19561 caggagaaat cgaccaatag gaaagaaata gctttagaaa aagaacctgt caataggtaa
    19621 gtcagcccag ccccaaagaa attatatttg acgactttat ccgccatctt gatgaaatag
    19681 cgttgtttcg ttttcttgtt ttcttcagat ttcttcatca acttaatcag ctgtaaaata
    19741 cggctgttca tctgattatc tgttacacga atgcgtaact ctccagtttc taatactgta
    19801 tttgcacaaa ccaaatcaga ctctcttttt tcaactggaa aactctctcc tgtcaaggaa
    19861 ctttcgttga ccatacctaa acctgaaact acttgtccat caaacagaat ttcatttcct
    19921 tgagataaga tcaagacatc tcctatttga acatcggaac tcttgatact aacaaccgta
    19981 tcgccctgta ctaggaatac atcgctctct tttgcaagaa gactctgttc taaatctgtt
    20041 gcagtttttt tcaaggacca ctgatctaaa tgattcccca aatcaagcat aaacatgata
    20101 ttgctagctg tcttggattg gttcataaac aaagacaata aaatagccga acagtccaag
    20161 acttccatcg ttagttcctt acgcgctagt gtttgatagg cttctctaat ataacccaaa
    20221 gcctgataac aagtccatat atagcgaata ggatacggca caaaactacg aaaaagtaca
    20281 cgcttaaccg ctgcacctga aacaatagaa taagcactct cttctctacg aatgggaaga
    20341 gtcatcaact cagaaacttt ccctttatca attcttttta aaaaggcttc tgcattatct
    20401 aatacagaaa agccttcttt tatgcgtaga gtaaagtgct gttgatccat gtaaaactgg
    20461 atagactcaa tccccttttc atctctcgcc aaggaacgaa gatagtcttg aatatccaag
    20521 gtaagtgaaa aagaagatga tagtcggata tgttggtatc ctctatgtag cactttaaaa
    20581 gacatattat tcacctataa ggctatctaa ttgctcttct tttttctctt gctcgtacaa
    20641 atatttggca tcttgcaaga catcgtctcc atgttgcttc acaacagaaa cagatgcatc
    20701 tagctcgtct ttcaacttgt aagccttagc caaagcttta gaataacctt ttttagcttc
    20761 cttacttgct aagattttca aaccaagggt accaaatgcg acaccaccca aaaataatga
    20821 agattttttc gcaacttttg caacggttaa tacttctttt aacatactta tttcctcctt
    20881 atcattatta tatagcaatt tagatataaa agcaatttca ttctataaat tggagaatta
    20941 gttttatttc tactgaatct cccatctact tattcctaaa gttgctttca tttgcctctt
    21001 ttgatacact taaactatga atacaaatct caagcccaaa cttcagcgtt ttgcttctgc
    21061 gactgccttt gcctgtccta tctgtcaaga aaatctgact ctgttagaga ctaatttcaa
    21121 gtgctgcaac cgtcattctt ttgacttggc gaaatttggc tatgtcaatc tagcacctca
    21181 aatcaagcaa tctgctaact atgacaagga aaattttcaa aaccgtcaac aaatcctaga
    21241 agccggcttt taccaagcta tcttagatgc tgtatctgac ttgcttgcaa gctcaaaaac
    21301 taccacaaca attttggata tcggttgtgg tgaaggattc tattctcgca aactacaaga
    21361 aagtcactct gaaaaaactt tctatgcctt tgacatctcc aaagattcag tccaaatcgc
    21421 tgctaaaagt gaacccaact gggcagtcaa ttggttcgtt ggcgacttgg cacgccttcc
    21481 tataaaagac gctaacatgg atatcctgct tgatatcttc tcacctgcca actatggaga
    21541 atttcgtcgc gttttatcca aagatggtat cttgataaag gttatcccaa ctgaaaatca
    21601 cctcaaagaa atccgtcaaa gagtacagga ccagctgaca aacaaggagt attctaacca
    21661 agatatcaag gagcatttcc aggaacactt taccatccta tctagtcaat ctgcctctct
    21721 gactaagact atcacagcag aacaactcca agccctactc agtatgactc ctctcctctt
    21781 tcacgttgac cagagcaaga ttgactggag ccaactgaca gagattacca tcgaagcaga
    21841 gattttggtt gggaaagcat tctaatactc ttcaaaccac gtcaacgtcg ccttgccgta
    21901 cgtatggtta ctgacttcgt cagtttcatc tacaacctca aaaccatgtt ttgagctgac
    21961 ttcgtcagtt tcatctacaa cctcaaaacc atgttttgag ctgacttcgt cagttttatc
    22021 tgcaacctca aagctgtact ttgagcaacc tacggctagt ttactcttta attttcattg
    22081 agtataaact agacttcgca aaagtagaaa acttaccgaa aatcttcaat atgacaaaaa
    22141 cgtataagaa caggtacaca aaccttaatc ttatgcgttt tgttatagtt tccatacaca
    22201 ttaaggggaa atagttgaaa tcagttcttt taataaccat tgaataccat atactacatt
    22261 taccccaaat atgatatagg ccgtataaat caagtatttc gatttttccc gcctcaaaga
    22321 atagatctta tacaaaataa ataaatttaa aataataaat aatagagaca aaatcttcct
    22381 ccaaaatcaa tcctaaaagt agccagtcaa gcatagctct aatctttatt ttcgattcga
    22441 tataacaaac ttatcaatga atagtaagtg atataaggcc agtaccagac cccaaacgct
    22501 accacgaaaa gagaattctt gatgattgag agtaaacaaa tcatggttac caatatagag
    22561 gcaggtcaaa ataacaaata aaatccaaaa taaatccgtc catttatatt ttgaaaaata
    22621 tttttttaac ataatagcat atttttttga ctataataac agtatatgat aaaatgtaag
    22681 cagatacaaa taaaaaagag agaaaaggaa tgatcttata ccagatcatt ccttttctgc
    22741 tttctgtaaa tccctcggag tgtgtttggc gctttgatac gaagtgtcaa agctgtataa
    22801 acgttactat ttccaaaaaa gtaacagaaa attcctgctt tgtaggactg ctttgggtga
    22861 gtaatagaca tgtcgactca ccctatctcc tgatggcgaa aagaatttag caatggtgca
    22921 agttgttctg aactcgagaa aaaacatgcc gaaatcgaag aaaagcgtgc agaacttgaa
    22981 gcgaagaagc aagaaatgtt gaagcgcttg gataaataga atttagaaaa cagaaaaaac
    23041 taaaaagaat gtagggttta tttccctaca ttcttaaaat aacttagtac ataaatgaca
    23101 atgctgccac tgccgtcaat attgcaaaaa ctattttcca aattttttta ttttttccaa
    23161 aaatcttatc aggtaacaag cttattacaa gaaaggtaat aaacaacacc aatttaagtg
    23221 tgtatatcat aaaaacacct tctttcctac aattatatta taatacttta tgtaagcgaa
    23281 tacaagaggt gtgaggtaat caactacgaa aaaatataag gctgaggaca gtaaaaacca
    23341 acatttaaag ccttcactgt atctaggatt tccctatttt tagacaagat tgacccaaat
    23401 ctacatcatt aaaaaagcga atttcaatcg aaactcgctt ttttacaaga tgtattagta
    23461 taaatttgta tcttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt
    23521 tgctcaaagc accgctttga ggttgcagat aaagctgacg tagtttgaag agatttttga
    23581 agagtattag ttcaagtgcc agatgtcttc gttatactga gcgattgtac ggtcagatga
    23641 gaagaatcct gctttagaaa tgttaacgat gactttatcc aaccatgcgt cacggtcttc
    23701 gtagtcagca agcatttgct ctttgacttt gatgtagtct tccaagtcaa gaagagtcat
    23761 gaaccagtct ttgttgatca attcattgta aagacgttcc aagcgctctt tgtttccagc
    23821 tgcaagaact gcatcactaa cgatgaagtc aaccaatggt ttgatagctt cacgagcgta
    23881 gaattcgctt gatttgtaag ctgcttttgc gtaaaggtcg ataacagttt ctgaatcttc
    23941 accgaagatg tagatgtttt cttctccaac caactcagcg atttccacgt tagcaccgtc
    24001 catagtacca agtgtcaaag ctccgttcaa catgaatttc atgttaccag tacctgaagc
    24061 ttctttagaa gcaagtgaga tttgttctga gatatcacat gctgggataa ggaagcttgc
    24121 tgcagtaacg ttgtagtttt caaccataac tacttgcaag tgtggagcta ctgctggatc
    24181 gttagcaata acttctgaca tgcaaaggat caagtgaatg atatcttgag cgattgtgta
    24241 ggctggagct gctttaccac caaagaagat tgtgattgga cgagcaggga tgttaccagc
    24301 tttgatgtca aggtatttgt ggatcacgta caaagcgttc atttgttggc gtttgtactc
    24361 gtgaagacgt ttgatttgga tatcaaagat agaatttgga ttgatttcca caccttggtg
    24421 ttctttcaag tgacgagcca atttacgttt gttgtgagcc ttgatgcttt ccaatttttc
    24481 tttgacagct gctttgtctt cataagacaa cagtttttca agctcatctg cttcatggtg
    24541 ccaaccatct ccaagaatct catccaagta gtgagacaat cttgggttag catgcataag
    24601 ccaacgacgg aaagtgatac cgtttgtttt gttgttgaac ttttctgggt aaaggtcgta
    24661 gaaggctttc aactcagaat ttttcaagat ttcagtatgg agtgctgcaa ccccgttaac
    24721 actgtatccg tagtggatat ccatgtgagc catgtgaaca cgtccgctct catcgatgat
    24781 ttgaacagct ggatctttgt actctgcctt cacacgacgg tccaattctt cgatgattgg
    24841 taccaagtga ggaaccactt cttgcaagaa ttcaagaggc catttttcaa gcgcctcagc
    24901 aaggattgtg tggttagtgt aggcagtcat gctacgaaca attgagattg cttcgtcaag
    24961 ctcgatacca cgtgcagtca aaagacgaat caattcagga atcaccattg atgggtgagt
    25021 atcgttgatt tggacaactg cgtagtcagc aaggtcatgc aagttgcttc ctttttcgat
    25081 tgcttcgtcg atgatcaatt gcgcaccgtt tgaaaccatg aagtattgtt ggaagatacg
    25141 gagcaattca ccttgacggt cactatcatc tgggtaaagg aagagagtta agttgcgagc
    25201 gatatctgtc ttgtcaaagt tgataccatc tttaataata gaagaatcaa ctgaatccaa
    25261 gtcaaacaaa cgcaagcggt ttttagtcgc tgtttcataa ccagtaacat caatatcgta
    25321 aagagttgat gtcaaagtaa agtctgcaaa tggtacttgg tagctacggc ttgagcgaac
    25381 caaccagttt tgctctgtca accatgcatt tggaattgtt tcttgttggt tgtttttaag
    25441 aacttgttgg aaaagaccaa agtggtagtt aagaccaaca ccgtcaccat tcaaaccaag
    25501 agtagcaatt gagtcgataa agcaggcagc caaacgtccc aaaccaccat taccaagaga
    25561 tggttccaat tcaacttctt caacttcgat caagtcttta cctgcagctg caagttcttt
    25621 tttaacatcg tcgtaaagac caaggttaat caagttgttt gacaagagtt taccaatcaa
    25681 gaactcagct gagatgtagt aaactttttt cttaccagtg ttgactggtt tttggctgct
    25741 tgcaagcttg ctgtagttaa gaagagcaag gtaaagctct tcattgctac attctgcaat
    25801 ggttttattg taacgatttt gtacaaattc ttgtagtgat aacatgttta gttgtctcct
    25861 gattattgtc ttatttcttt aaatctacca aattttcatt aattcggcga taaattgttg
    25921 tcaagtcaag caaaccttcc tcgacagctg gtgtcaattg atcttcagtc atacgccaag
    25981 accagtttcc accaagggta gatgggaagt tcatacgagc tgcctcatcc aattctagta
    26041 aatcttgcat agttgcaatt gccataaagc taactgatga aaatactgta cgaagcatag
    26101 cgtgtaccac tgtttcgtat tctttacggt tcgtgtaacg agccatgtac tcacgagtcg
    26161 catcatcaat ctcattacgg taccaaccaa gaaccgtatt gttatcgtgt gttcctgtgt
    26221 acataactga gttagcaggt gccaagtgtg ggctatcaat actttcgtct tctgggttga
    26281 aggcaaattg aagaatcttc attcctggga agccagtacg ttcacgcaat tcgatcactt
    26341 catctgtcat gaagccaagg tcttctgcga tgatgtttag ctcaccaagt tcttccttaa
    26401 cggctgcaaa aagcttgtag cctggacctt tcacccactc accaggtgct gctgtatcgg
    26461 aaccagcagg gatttcccaa taagattcga agccacggaa gtggtcgata cgaacgatat
    26521 cgtagatttt gaagctttca cgcaagcgtt caatccacca tttgtagccg tctttgtcca
    26581 ttgcttccca gtcatagatt gggttacccc aaagctgacc agttacagaa aactcatctg
    26641 gtgggcatcc tgcgatacaa gtagccttac cattgacatc tgttttgaag agatgtggat
    26701 ttgcccacat atcacttgaa tcttccgcta cgtagattgg catgtcccca acgatttcga
    26761 tgtggttgtc gttagcgtaa gctttcaatt tcaaccattg ttggaagaag aagtattgag
    26821 tcacacggtg gtaaaccaac ttgtctgcca attgctcacg atagctttca agtgctgaag
    26881 ctttacgagc acgagcatct gcatctggcc attcagtcca agcaagattg tcaaaatact
    26941 ctttgatagc catatactca gcaaagagct caagccatga ttggttgtct tgagcaaatt
    27001 tctcaaaatc tttaacatct ccgacttcaa agaaacgttt caccgctttt tctaaaagag
    27061 gacgacgtgc atagtagatt ttagcatagt caacttcaga cgcatcgcta ccaaagtcaa
    27121 ctccttcaag gtcacttgct tccaacaaac cttgctccac caagatatct aaatcgataa
    27181 aatgagtgtt tcctgcgaag gctgagaaag attggtaagg agaatccccg taactagttg
    27241 ctcctaatgg aaggatttgc cagtaacgtt gttttgtacg gaccaagaaa tcaacgaagt
    27301 cgtaagcact ttgaccaaat gatccgattc cgtaagctcc tggaagagaa gagatgtgca
    27361 tcaacacacc actttgacgt tttttcataa tagcacctcg tgtgttaaaa taatggaacg
    27421 ttgcgtattt ttcagacgca aacgtttgcg ttacttataa gtatactcct tttcaagcat
    27481 aattgcaagc gtttttaaaa aacttttttg attattttta aggagactaa ctcattttag
    27541 caaagataac ttaaaactat ctaatcctaa ggtttgactc tcacgagaca gtctacaaag
    27601 tacaaaacct ccttagggag cttgaattta tatgcaacaa agcacaaacg tctatagaaa
    27661 atagataggg attagaacca gggaggtagc ccctcctgat ttccctcttt agacagattc
    27721 catatatttt tattaaaaat actgtattct tatctatttc atacttttct tctattaaaa
    27781 tgcaaaatta tgctatcaaa tcaagcttaa aaatttttta aaatttttac aaaaaatact
    27841 tgcaaccgtt ttctatttgt gctatactaa gctcataaag gaaaacgttt gcgtttcctt
    27901 atcaataaaa cttgctattc tttgggagga atacactatg tcatctaaat ttatgaagag
    27961 cactgcggtg cttggaactg ttacacttgc tagcttgctt ttggtagctt gcggaagcaa
    28021 aactgctgat aagcctgctg attctggttc atctgaagtc aaagaactca ctgtatatgt
    28081 agacgaggga tataagagct atattgaaga ggttgctaaa gcttatgaaa aagaagctgg
    28141 agtaaaagtc actcttaaaa ctggtgatgc tctaggaggt cttgataaac tttctcttga
    28201 caaccaatct ggtaatgtcc ctgatgttat gatggctcca tacgaccgtg taggtagcct
    28261 tggttctgac ggacaacttt cagaagtgaa attgagcgat ggtactaaaa cagacgacac
    28321 aactaaatct cttgtaacag ctgctaatgg taaagtttac ggtgctcctg ccgttatcga
    28381 gtcacttgtt atgtactaca acaaagactt ggtgaaagat gctccaaaaa catttgctga
    28441 cttggaaaac cttgctaaag atagcaaata cgcattcgct ggtgaagatg gtaaaactac
    28501 tgccttccta gctgactgga caaacttcta ctatacatat ggacttcttg ccggtaacgg
    28561 tgcttacgtc tttggccaaa acggtaaaga cgctaaagac atcggtcttg caaacgacgg
    28621 ttctatcgta ggtatcaatt acgctaaatc ttggtacgaa aaatggccta aaggtatgca
    28681 agatacagaa ggtgctggaa acttaatcca aactcaattc caagaaggta aaacagctgc
    28741 tatcatcgac ggaccttgga aagctcaagc ctttaaagat gctaaagtaa actacggagt
    28801 tgcaactatc ccaactcttc caaatggaaa agaatatgct gcattcggtg gtggtaaagc
    28861 ttgggtcatt cctcaagccg ttaagaacct tgaagcttct caaaaatttg tagacttcct
    28921 tgttgcaact gaacaacaaa aagtattata tgataagact aacgaaatcc cagctaatac
    28981 tgaggctcgt tcatacgctg aaggtaaaaa cgatgagttg acaacagctg ttatcaaaca
    29041 gttcaagaac actcaaccac tgccaaacat ctctcaaatg tctgcagttt gggatccagc
    29101 gaaaaatatg ctctttgatg ctgtaagtgg tcaaaaagat gctaaaacag ctgctaacga
    29161 tgctgtaaca ttgatcaaag aaacaatcaa acaaaaattt ggtgaataaa aaatttgttc
    29221 aaggggggtg gaaatcaaat ccccctttga atttatcaat agagacacaa ataatttagc
    29281 tttcttataa aaaagtagta tcctatgaaa ggagttaata tggaaaagca acaacctagt
    29341 aaagcagccc tgctgtctat cattcctggg ttaggacaga tttacaataa acaaaaagcc
    29401 aaaggtttta tcttccttgg tgtaaccatc gtatttgtcc tttacttcct agcacttgca
    29461 acccctgaat tgagcaacct catcactctt ggtgacaaac caggtcgtga taattccctc
    29521 tttatgctga ttcgtggtgc cttccatcta atctttgtaa tcgtttatgt actcttttat
    29581 ttctcaaata tcaaagatgc acatacgatt gcaaaacgca ttaacaatgg aattccagtt
    29641 ccacgcacac tcaaagacat gatcaaaggg atttatgaaa atggcttccc ttacctcttg
    29701 atcattccat cttatgttgc catgaccttc gcgattatct tcccagttat cgtaaccttg
    29761 atgatcgcct ttaccaacta cgacttccaa cacttgccac caaacaagtt gttggactgg
    29821 gttggtttga ccaactttac aaacatttgg agcttgagta ccttccgttc tgcctttggt
    29881 tctgttcttt cttggactat catttgggct ttggcagctt ctactttaca aatcgtaatt
    29941 ggtatcttca cagctatcat tgccaaccaa ccatttatca aaggaaaacg tatctttggt
    30001 gttattttcc ttcttccttg ggctgtccca gccttcatca ctatcttgac attctcaaac
    30061 atgtttaacg atagtgtcgg tgctatcaac actcaagtat tgccaatctt ggctaaattc
    30121 cttcctttcc ttgatggagc tcttattcct tggaaaacag acccaacttg gactaagatt
    30181 gccttgatta tgatgcaagg ttggctcgga ttcccataca tctacgtttt gactttgggt
    30241 atcttgcaat ctattcctaa cgacctttac gaagcagctt atattgacgg tgccaacgct
    30301 tggcaaaaat tccgcaacat cactttccca atgattttgg ctgttgcggc acctactttg
    30361 attagccaat acaccttcaa ctttaacaac ttctctatca tgtacctctt caatggtgga
    30421 ggacctggta gtgtcggagg tggagctggt tcaaccgata tcttgatctc atggatctac
    30481 cgtttgacaa caggtacatc tcctcaatac tcaatggcgg cagctgttac cttgattatc
    30541 tctatcattg tcatctcaat ctctatgatc gcattcaaga aactacacgc atttgatatg
    30601 gaggacgtct aagatgaata actcaattaa actcaaacgt agactgactc aaagccttac
    30661 ttacctttac ctgattggtc tatcaattgt aattatctat ccactgttga ttaccattat
    30721 gtcagccttt aaagcaggta acgtctcagc ctttaaacta gatactaata tcgacctcaa
    30781 ttttgataac tttaaaggcc tcttcactga aaccttgtac ggtacttggt acctcaacac
    30841 tttgattatc gccttaatta ccatggctgt tcaaacaagt atcatcgtac ttgctggtta
    30901 tgcttacagc cgttacaact tcttggctcg taaacaaagt ttggtcttct tcttgatcat
    30961 ccaaatggtg ccaactatgg ccgctttgac agccttcttc gttatggcgc ttatgttgaa
    31021 cgcccttaac cacaactggt tcctcatctt cctctacgtt ggtggtggta tccctatgaa
    31081 tgcttggctc atgaaaggct acttcgatac agtgccaatg tctttagacg aatctgcaaa
    31141 actagacggt gcaggacact tccgccgctt ctggcaaatt gttcttccac ttgttcgccc
    31201 aatggttgcc gtacaagctc tctgggcctt catgggacct ttcggggact acatcctctc
    31261 tagtttcttg cttcgtgaga aagaatactt tactgttgcc gtaggtctcc aaaccttcgt
    31321 taacaatgcg aaaaacttga agattgccta cttctcagca ggtgctatcc tcatcgccct
    31381 tccaatctgt attctcttct tcttcctaca aaagaacttt gtttcaggac ttacaagtgg
    31441 tggcgacaag ggataattta tccccgccac cctttttcat tttatactct tcgaaaatct
    31501 cttcaaacca cgtcagcttt atctccaacc tcaaagttgt gctttgagca acctgtggct
    31561 agtttgcact ttgattttca ttgattatta gcaattgtca ctgtaaataa tatccttgta
    31621 gcaagcaatt tttctcctag acttgaaata aagcgcattt ctctatataa taatactcat
    31681 atagaaaaca ccttttagaa agatacctat gcttccatat ccattttcct atttttcaag
    31741 tatttggggg tttcgtaagc ccctgtccaa acgtttcgag ctcaactggt ttcaacttct
    31801 ctttaccagt atcttcctta tcagcttgtc tatggtaccc attgctatcc aaaacagctc
    31861 ccaggagacc tatccgctag aaacttttat cgataatgtc tatgaacctc tgacaaatga
    31921 ggttgtccag gatctctctg aacatgctac aattgtcgat ggcacattaa cttatactgg
    31981 aacagttagt caagcctctt ctgttgtgat tggttcaagt caaatcaagg aattacctaa
    32041 gaacttgcaa ctgcatttcg atacaaatga gctagtcatc agcaaggaaa gcaaggaact
    32101 gacccgcatc tcttaccgag ccattcagac tgagagtttc aaaagcaaag acagcttgac
    32161 ccaagcaatt tctaaagact ggtaccaaca aaatcgtgtc tatatcagcc tcttcctagt
    32221 tctcggtgcg agcttcctct ttggtttgaa tttctttatc gtctctctag gagctagtct
    32281 tctcctttat atcactaaga aatcacgcct cttttcattt agaaccttta aagagtgcta
    32341 tcactttatc ttgaactgtt taggattgcc gactctgatt acacttattt tgggattatt
    32401 tggccaaaat atgacaaccc tgattactgt acaaaatatt ctttttgttc tgtatctggt
    32461 cactatcttt tataaaacac atttccgtga tccaaattac cataaatagg agatttttat
    32521 gcccgttacg attaaagacg tggccaaggc tgctggtgtt tcgccttcaa ccgtaacccg
    32581 tgttattcaa aataaatcaa ccattagcga cgaaacaaaa aaacgcgttc gcaaagctat
    32641 gaaggaactc aactaccacc caaacctcaa cgctcgtagc ttggtaagca gctatactca
    32701 ggttatcgga ttagttcttc ctgatgactc agacgccttc taccagaatc ctttctttcc
    32761 atcggttcta cgtggcatct ctcaagtcgc atctgaaaac cactatgcca ttcagatagc
    32821 aacagggaaa gatgagaagg agcgtctcaa cgctatttca caaatggtct acggcaagcg
    32881 tgtagatggg ctaatctttc tctatgccca agaagaagac cctctcgtaa aactcgtcgc
    32941 agaagaacag ttccccttcc ttatcttagg taaatctcta tctcctttca tcccacttgt
    33001 cgacaacgac aatgttcaag ctggttttga tgcgactgaa tatttcatca aaaaaggctg
    33061 caaacgcatt gcctttatcg gaggaagtaa aaagctcttc gtgaccaaag accgtttaac
    33121 aggctatgaa caggcgctta aacattacaa acttaccact gacaacaatc gcatctactt
    33181 tgccgacgag tttctggaag aaaagggcta taaatttagc aagcgattat tcaagcacga
    33241 tccacaaatt gatgctatca tcacaaccga tagcctccta gctgaaggtg tttgtaacta
    33301 tattgccaaa caccagctgg atgtccctgt tctcagcttt gactcggtta atcccaaact
    33361 caacttggca gcctatgtcg atatcaatag tttagagctt ggtcgtgttt cccttgaaac
    33421 tattctccag attattaatg ataataaaaa caataaacaa atttgttacc gtcaattgat
    33481 cgcccacaaa attatcgaaa aataagagac tgggcaaaaa gtcgttaaaa gcaaaaacgc
    33541 atagtatcag gtattgaaaa aacttgatac tatgcgtttt aatgtgggaa gatttacttc
    33601 cttttctact gaaattgagt cttttcccaa gatcttttta tactcaatga aaatcaaagt
    33661 gcaaactagg aagctagccg caggttgctc aaaacactgt tttgaggttg cagatagaac
    33721 tgacgaagtc agtaacatat atacggcaag gtgaagctga cgtggtttga agagattttc
    33781 gaagagtatt aatcactaat tatctatctc aacaaatctt cctagaatat gaacattttc
    33841 cgagacagag acaaaggagc ttggatccac ttgtgtcata atctgtttaa attcattaaa
    33901 ctctgcacgt gtaatgacag tgattaaaac tgcctttctc tcgtgattat aggttccttc
    33961 tgcatcgtgg atcatggttg ctccgcggtg caatttttta tggatttttt caattacctt
    34021 ctctggatga tttgtcacaa tcatggcctg catacgcttt tgcttagtaa agactgcgtc
    34081 tgtcacacgg ctagagacaa agatggtaat catagaataa agagcgtatt tccaaccaaa
    34141 ggtcaaacct gctatcagca tgatagttcc atttaccaag aaagaaatac taccgacatt
    34201 cttacccgtt ttcttgcgaa tagtcaggct gacgatatcc gtcccaccac tggagatatt
    34261 gtttcgaaga gcaaaaccaa tccccaaacc cataacaaca cccccaaaaa gggaattgat
    34321 aatgggatcc tccgtcaagg ttgccacagg gacaaactgg ataaagaagg aactcataga
    34381 taccgtgata aaggtaaaga cggtgaactt atggccaatc tgataccaag ctaagaccat
    34441 caaagggaag ttaatggcgt agaagcttag cgaaatcgga atatgaaaac caaaccagtg
    34501 attactcaag gcagagataa tctgtgccag acctgttgca ccactcgaat acacatgccc
    34561 tggttggaaa aagaaattaa ctgctactgc tgataaaaaa ccatagacca gagaggccga
    34621 aatcttctca tcatactttt ctcgagagat actttgtaag acacgtaaaa tttttatctg
    34681 ataagcaaag cggcgcagat aatagcgcca ccgcttaatt cgttttgctt gtttcatctt
    34741 cttctacttg taagctgagt tcctctagtt gtttgagagc gactgttgat ggagcttgtg
    34801 tcattgggtc agttgccttg ttgttcttag gaaaggcaat gacttcacgg atattttctt
    34861 ctccagcaag caacatgaca aaacggtcaa gcccgatagc caaaccaccg tgtggtggga
    34921 aaccatagtc catggcttca agaaggaaac caaactggtc attggcttct tcagctgaga
    34981 aaccaagagc cttgaacatg cgttcttgaa ggtctttttg gttgatacga aggctaccac
    35041 caccaagctc ataaccgttc aagacgatat cgtaagcaat ggcacgaacc ttagccaaat
    35101 caccttctaa ttcgtgagca gtctcttcct gtggaagggt gaaaggatgg tgggcgctca
    35161 tgtagcggcc ttcttcttca gaccattcaa acatcggcca gtcaaccacc caaaggaagt
    35221 tgaacttatc attatcaatc aagccaagct ctttagcaat acgtccacga agggcaccca
    35281 gtgttgcatt agccacttca agcgtatccg ccacaaagag aaccaagtcc ttatcttcaa
    35341 gagcaagcgc tgttgtcaat tcttcttgga taccagtcaa gaacttggca actggtccgt
    35401 ttaattctcc atcaaccacc ttaacccaag caagaccttt ggcaccatac tgtttggcta
    35461 cttccgtcat cttgtcgatg tctttacgtg aatagttgtc cgcagctcct ttgaccacaa
    35521 tcgcttttac agcaggtgct tctgaaaaga ctttaaagtc tacacctttg accacttctg
    35581 tcaagtcctg aagcaacatg tcaaaacgag tatctggctt gtcagaaccg taaagagcca
    35641 tagcatcatc gtatttcaca cgagggaacg gtagcgttac ttcgatgcct tttgtttcct
    35701 tcatcacgcg cgcgatcaag ccttctgtaa tatcttggat ttcttgctca gtaaggaagg
    35761 acgtttccaa gtcgacctga gtaaattcag gctggcggtc tccacgcaag tcttcgtcac
    35821 ggaaacattt aacgatttgg tagtaacggt caaaaccagc attcatcaag agctgtttcg
    35881 tgatttgtgg actttgagga agagcgtaaa aatgcccctt attaacacga gacggcacta
    35941 aataatcacg cgccccttca ggcgttgact tagaaaggaa tggtgtctcc acgtcgataa
    36001 actccaactc atccaagtag ttgcggatag agtgggtcac cttggcacga agtttaagat
    36061 tttccaacat ttctggacga cgaaggtcaa ggtaacggta acgcaaacgt gtatcgtcat
    36121 ttgcctcaat gccatcctta atctcaaatg gtgttgtctt agctgtgtta agcacaataa
    36181 gagctgtcac gtttaactca accgcaccag ttggcaactt atcattggct tgctcacgcg
    36241 cagcgacctg accagtcacc tcaataacaa attcgctacg aaggctttca gctgttgcca
    36301 taacctctgc agatactttt tcagggttga taaccaactg catgattcct tcacggtcac
    36361 gaagatcgat aaagatcaaa ccaccaaggt cacgacgacg gccaacccat cctttcaagg
    36421 ttatttcttg tccgatgtgt tcctcacgaa cacgaccagc atacatacta cgtttcatta
    36481 tttctctcct cttttattct gttactattt taccataaaa gcgcaggctc ttcatgaaaa
    36541 tcatcagaaa agtttgccag tctttaaaag tcagatgaaa gccctaaaaa ttagcgctaa
    36601 tactcttcga aaatctcttc aaaccacgtc agcgtcgcct taccgtaggt atggttactg
    36661 actccgtcag tttcatctac aacctcaaaa ccatgttttg agctgacttc gtcagtttca
    36721 tccacaacct caaaacagtg ttttgagcaa cctgcggtta gcttcctagt ttgctctttg
    36781 attttcattg agtataatac aaaaatccga tgaacttcac cggactcttt tattttgaat
    36841 ttttgcctgc tttacgcttt tcagcgattt cggctgcctt tcgaggcaag acaatttccg
    36901 ttatgtaagc cgtcccaaaa cgcagtacac ctgcaatagg agcaaagaca actgctagat
    36961 agttatagaa gaaatcgcct ttgaaggcat aagctagccc tccaatgatg aaaaatagaa
    37021 cgactgcctg aatcactgct actaaaatta ctcgtttcat gtgacctcct gactctatta
    37081 tagcatgaga atcatcaaaa agccgactaa attattcaaa gcgtgaagag aaatactgta
    37141 gaccagacct tttctgctaa tgtaagccaa acccaaacta aaaccaaggc taaaatagac
    37201 aaaaaattgt tgcacatcac ctggaaaatg aatcaaggca aatagaagac tagataccag
    37261 aagaaaaatc agggttcgtt tactattgtc ctgcttagga aagagatagc gtgctaacat
    37321 ccctctaaaa acaatctctt ccgtcaaagg agcaaaaata accacagcaa agaatgagaa
    37381 aagtggttga gacaaggtca agtctgtcgc tatttgctga tttactgaag gatcatctgg
    37441 caagaagaat tgaacgacca gagataagaa ccaaaccaag gcaggaagcc aaataaatcg
    37501 gttaaagccg ctcttctcaa tataaacagg agctttctga taccatttgt aaatgccgta
    37561 cacatatact ccagccaaga ccacatagag tagagtaaca gcatagggtg aagcgcctaa
    37621 aacaagcgac gcagtcgcga gcccctgaat aaagccatag ataaagaaaa aggatagaag
    37681 ggctagaaga aaccagccaa ggtttttaag tagtttcata gataactcct ttatttgaaa
    37741 taacgtttta ccataggtaa ctgcatcaca ttgatataaa catggatggc tcctacaagc
    37801 aagaaagcta gtaactgaat ctctcctgtc aagaaagaaa tgataataag aaaaatatat
    37861 aaggctggta agacatattg gtgtaattgg aataaaattc gaaaactctg ttccaaatta
    37921 gcctgacgct ccccttcatc ataagaattt atatagttca agacatcctt tggtgtagcg
    37981 aaaaattcca aatcaaactg acgaacaatc gcaatggttt taaaaagaga tttttgagcg
    38041 actaagaata ccacaaagag taagaaagaa aggaaaaatg tttgagggtt tgtatgcaat
    38101 ataatcacct cacttaatga aataaaaata gccaatggaa tcgctacacc tgtaatatta
    38161 aaagcaatgg ttccaaactc aagattccga tacatttgca cataataggt ttcattcaga
    38221 tcgtcatcca tttcctcttg atacaaggaa tgaaattttc tacttttctt taagaaattg
    38281 aaagtcaaaa acatactaat gaaacctatc agtaaacaaa tagctgatat ccatggcatc
    38341 aaggctttta catctaaaat aatttcgtgg gattcgacac gtgccttaaa catccctaca
    38401 aacatgccca agaacccccc aaagacaata gacatcaaaa ataacaatct acgtttcttt
    38461 ttcatattca ttctcctttt tcacttgcta gatttttgga tttcttttca atccattcaa
    38521 ttactgggat gagagcaaag tagacccaaa caaattggtc gctttgatag ggattaaacc
    38581 agcttaggtc catcccaatc agtagaaata cgctgactaa taaagctatg accactacat
    38641 aataaatcac tttatacttg ttcatcactc gtcctcctcc aaacgaaata ccgattcgac
    38701 tgtttcgttg aaaatttgag atattttcag ggcaatgata atggatgggg tgtactcatc
    38761 ccgttctagt aggctaatgg tctgtctgga aacccctgcc agtttggcta ggtcggtttg
    38821 attgagacca tcgcgagctc gaagctcttt tagacgattt tttagttgca tgttacacac
    38881 ctactctccg tcaaattcaa cggtttggat atcctcaata cgttgcaact tgaatttttc
    38941 ttttcccgta ttatctacac gtcgtagctt tacccattcc tcatcaacat ccacaacttc
    39001 ccagttatct ggcccaatat acactcccgt tataattggt tcctttccaa tcatttcttg
    39061 taataatctc gacatttctg catttccttt ctcttttcgc tcaagtcttt tgattttctt
    39121 ctctagtttc ttgatttttt tagaatcatt agaataaaag aaaatcagaa atagtataaa
    39181 ccctagtacc cacatcatag ctcctttctt cttttctctt aacttgctta cattgtaaca
    39241 catctttttc tttttgacaa gtatagttgt caaaaagttt atgatttttg tcattttgca
    39301 aaagaaaaag gtcaggagta agttcctgac cactttatct atcattaata ctcttctaaa
    39361 atatcttcaa accacgtcag cttcaccttg ccgtaggtat ggttactgac ttcgtcagtt
    39421 tcatctacaa cctcaaaaca gtgttttgag caacctgcgg ctagcttcct agtttgctct
    39481 ttgattttca ttgagtataa aatcctagtt tttcaaagat ttctgagaag ttttggctga
    39541 ttgtctcaag tgacacttgc acttcttctc gggtttggtt gttcttgacc gtcacttgtc
    39601 cgctttcgac ttcgctctct cctagggtga tgagggtctt agccgcaaag acatctgctg
    39661 acttgaactg agctttgagc ttacggttga ggtaatcacg ctctgctttg aaaccttgtt
    39721 ggcgaagagc ttggactagt tctagggctt tgacatttgc tccatcaccc aagactgcga
    39781 tatagacatc tagggcgttt tcgataggga gggccacgcc ttgtttttca aggatgagaa
    39841 gcaggcgctc tacaccaagc ccaaaaccaa atccagcagt ttcagggcct ccaaagtaag
    39901 caaccaaacc atcgtagcga ccacccgcac agactgtcaa gtcattgccc tcaatctctg
    39961 tgataaactc gaaaatggtg tggttgtagt agtccagacc acgcaccata ttggtatcga
    40021 tgatgtaatc tactccaaga ttttccaaca tctgacgcac agcatcaaaa tgagtttggc
    40081 tttcttcatc aagaaagtcc aagatagacg gcgcattctc tactgccacc ttgtcttctt
    40141 tttccttaga gtccaagaca cgaagaggat tttcctccaa gcgacgttgg ctatccttag
    40201 acaaggtctc cttgagcggt gtcaaatagt caatcaaggc ttggcggtag gctgcacggc
    40261 tctcaggatt tccaagagtg ttgaggtgca atttgacacc ttgaataccg atttccttca
    40321 aaaaatgggc tgccataacg attgtttcca catcggtagc tggattgcta gagccaaaac
    40381 actcaacacc aatctggtgg aattggcgca agcgccctgc ctgtggacgc tcataacgga
    40441 acataggtcc catgtagtag aacttgcttg gcttttgcac ttctggggcg aagagtttat
    40501 tttccacata ggaacggaca acgggcgcag ttccttctgg acggagggta atatggcggt
    40561 cacccttgtc atagaaatcg tacatttcct tggttacgat atccgttgta tctccgacag
    40621 agcggctgat aacctcgtaa tgctcgaaaa taggcgtacg cacttctgcg tagttgtagc
    40681 gcttgaaaat ttcacgggca aagccctcaa cgtactgcca cttagcagac tcagcaggta
    40741 aaatatcctg cgttcctttt ggtttttgta atttcatagg gaatcctctt taaacttaat
    40801 agtcttattt taccataaat agagggatta aaacagtgag aaaaaaatta ggatttagat
    40861 atcatttttg agattaagaa ttgtcaaaaa aatagctagc aaggaaaaac caacaaatag
    40921 catccaagtc aactgtatat tccatacggc tactagtgaa aaacaaactg ttcccacagg
    40981 tatggataag gtaaacaata gacctaaaaa attactagta cgagctagaa cctctggagc
    41041 tagatttttc atgagcatgg cactaatctt tggttgaact ttaccagaca catacagagt
    41101 aaagaagaga aatagcaaac caagcacgac ttgattgaat aaattagcca aaccaactag
    41161 actaagtcct acggtcgccc acatcatcaa tctaggcaag gactgcttcc aaaaataatc
    41221 attgcccgta aggctactga tgatgattgc tactaaaaca cagaattgat tgataaatag
    41281 tgcctctgta taagaaaaat tcaagagaga atggctcaaa aagaagatat tataaattcc
    41341 acccaaagcg ccacccaagg aattaataag caagacagca aagagcataa aaccaaagtt
    41401 tttctgtcca cttttaagaa aaacgagacg taaatttcgg taaattgtta ggaactggtc
    41461 tttgatagaa agcttctcat tttttaagtt ttcaccatca gcagatgaca ttgacaggct
    41521 caatttgctt tttcctaaaa agaggatagt ggctgatact aggaaaaagc aggcattgat
    41581 tcccgcaacg agggaaaaat tgttgaccga tagagctaag agccagactc cgaaagcttg
    41641 accaccaata gctgaaatat aggtgatgaa ctgtgaaaaa gaataagcct ccatcaaatc
    41701 atcttcagct actttttcct taataagagg catacgcagg ccacctgcaa aatcactgat
    41761 gatatcacta atgacattga tcaaacacag gctagaaaag gcaaagagac tagcttgctg
    41821 aacaactagg gctgctagaa aaaatagaac cgcctgaaac aaaccgctat agaccatcca
    41881 tttgaccttg tccctcgtgt aatctgcccg aatccctgca aaaactgtaa agaaggtcgg
    41941 aagaatcatg acaatattcg ccatagcaac agcaaaagat gcttgtgaca aggtcgatgc
    42001 atagacgata aagaccaggt tgaaaatcga agcaccaaaa gcattgaaga agcgtgataa
    42061 agtcaaaatt ctataagctg gatttctaaa caatagtttc atagataatc tccctccttg
    42121 ttctaagttc tacatcaaga atagctttag tatagcactt atgaatttgc gaaacgattc
    42181 ttttgaatat atgcaacaaa caaaatgagc aaaaaaacga tagaactttt gtaatgacct
    42241 gagagagggc aacagttcta tcgcttcaaa ttttttcttg gtttgcagat attcaacatt
    42301 cggtcgtatt tctatagtat tcggcagatt tattacagcc aagcatctca aaaatacgga
    42361 cagcatcctc catctttttc tggccttcct tgactctacc ttgcttgcta tcaaggagac
    42421 cttctgccca cagataaaca attcggaaat aggtctcatt ttccttgtag aaatgctctt
    42481 cgataacacg tttaaaataa taggcattgg taaattcttc acactcaata ctagctaaaa
    42541 agccattcaa tagtatagta tgaaaaaggt ttcgattgcc agacatttcc attagaaaat
    42601 cagatttacg taccatttct cgtacatatc tagtaaaaag agaaacagat aaaaatggag
    42661 aactgactga aaataaattg agttcataga ttccccagat ctcggtagaa aacaaataat
    42721 catgaaggac ttttccttcc tctgctgtta actctaccct ttcatctatg ctcttcatat
    42781 aagacttgat aataatggca tttagaatat gtttctgttt gttgtgagaa tgggcatgct
    42841 tttgatactc cctgcgatat aagtcctcaa gaggtgctat attctttggt tccaagacat
    42901 ctgtaatttc ttttctcaac tcagaatctg tatcatactg gaaacctctc gccagaaaga
    42961 ggatctcctc cacactggca gatatatttt ccagagcaaa tagaaacttt tccaccgaaa
    43021 gctcactctg acctgtttca aaacgggaca acatagacgg cgaaaattgt cctccggtta
    43081 cttgtctcag tgagatattt cttgactctc gtaattgtct aaagactttt ccaatctgct
    43141 ccatagactt ccccttgatt ccgtattttc ttcattttat catatttttc agaaaattca
    43201 tcaaaaactt gccaaattgt cagaattatg agaaaataga ggatatttat cacgtggagg
    43261 gactgctatg agagacgata tcaaaatcaa tgaccgtgct ttggccttgc aagaccaaat
    43321 catcgaaaaa ctagagaaag tttttgatac agatgtggaa ttggatgttt acaatctagg
    43381 tctgatttat gaaatcaatc tggatgaaac ggggctctgc aagattgtca tgaccttcac
    43441 cgatactgcc tgtgattgcg ccgaaagcct gcctattgaa atcgtggcag gtctgaaaca
    43501 aatcgagggt atcaaggata tcaaggttga agttacctgg tcgcctgctt ggaaaatcac
    43561 acgaatcagt cgctatggcc gtattgccct tggactacca cctcgttaag caggccaatc
    43621 acttttaaag atgaaaaaag caagccgaaa atggcttgct ttttgatact caatgaaaat
    43681 caaagggcaa actagaaaac tagccgcagg ttgctcaaaa cactgttttg aagttatgga
    43741 tagaactgac gaagtcagct caaaacactg ttttgaggtt gtggatagaa ctgacgaagt
    43801 cagtaaccat acctacggca aggcgacgtt gacgtgattt gaagagattt tcgagtatga
    43861 gtttattttt tacctgactt gtccatattc cagaagtctg tcacggctcc gcgtgaagca
    43921 gatgatacga tgtgggcata tttaccgagg acaccacggc tgtaaagtgg tggcaaggtt
    43981 gtttctgcct tgcgtttttc aagttcttct tcggatacgg ccatggaaat ttctttggta
    44041 tcttggtcaa ccgtaacgat atcgccggta cggagatagg caattggtcc accatcctga
    44101 gcttcaggag cgatatgtcc aacaacaaga ccataagtac caccagagaa acgtccgtcc
    44161 gtcaagaggg ccaccttatc tccctgacct ttaccaacaa tcattgaaga aagtgacagc
    44221 atctcaggca taccaggacc acctttaggt ccaacaaaac gaacaacgac tacatcgcca
    44281 tcaacgattt catctgtcag aacggcctga atcgcatctt cttctgagtc aaagacctta
    44341 gctggcccaa cgtgacgacg cactttaaca cctgatacct tggcaactgc accgtcagga
    44401 gcaaggttcc cgttcaagat gataagcgga ccatccgcac gttttggatt ttcaagtggc
    44461 atgataactt tttggcctgg agtcaagtct gcaaagtcag ccaagttttc agctacagtc
    44521 ttaccagtac atgtgatgcg atctccgtga aggaaaccat ttgccaacaa gtacttcata
    44581 accgcaggga caccaccgac ttcgtagagg tcttggaaga catactgacc agatggtttc
    44641 aagtcggcca agtgaggcac acgttcttga atcgtattga agtcctcaag tgacaagtca
    44701 acatttgcgg catgggcaat ggcgagcaag tgaagagtgg cgtttgtaga accaccgaga
    44761 gccatcgtta cagtaatagc atcttcaaag gcttcacgag tcaagatatc tgatggtttg
    44821 agaccaagtt ccaacatctt aacaacagca cgtcctgctg cttcgatatc ttctttctta
    44881 tcagctgatt cagctgggtg agaggatgac cctggcaaac tcatccctag aacttcgata
    44941 gcagttgcca tggtattagc agtatacata ccaccacaac caccagggcc agggcaggca
    45001 ttacattcaa gacgtttcac gtcctcagct gtcatgtcac cgtggttcca ttttccgata
    45061 ccttcaaaga cagaaaccaa gtcgatatct ttaccatcaa gatttcccgg tgcaatagtt
    45121 ccaccatagg cgaaaatagc tgggatatcc atattagcaa tagcaatcat agatccaggc
    45181 atgttcttgt cacagccacc gatagcgacg aaggcatcga cgttgtgacc actcatagcc
    45241 gcctcgatgg agtccgcgat gatgtcacga gatgttagag agaaacgcat accaggcgtt
    45301 cccatagcga tcccgtctgc tacggtaatg gttccaaact gtacaggcca agcgcctgca
    45361 gatttgacac cttctttagc cagtttcccg aaatcatgca agtgaatgtt acatggtgta
    45421 ttttccgccc aagtcgaaat cactcctaca atcgatgttt caaagtcctt atctgtcata
    45481 ccagtcgcac gaagcatagc acggttaggt gatttaacca tgctgtcata aatgctactg
    45541 cggtgacgtt tatctaattc agtcatctta tccctcccat ttcagttttt actattatag
    45601 cacaatttaa aggcaatgaa cagaataaaa ttcttgaatt ttcagaaaat tctatacgca
    45661 tgtgaaatat ttaaaattaa aaacaacaaa gcggattagt gcactttctg atgaccagaa
    45721 tatgcttttt aatccgcttt ttttaaataa cgtaatgtaa tttttacaga aattctttca
    45781 gataagtgta tttaacatct atcttgcatt ataaatttct agaaccttct cttttatatt
    45841 cgattcactc aaaccatact cattaagaag ataatccatt ttccctactt gaccaaatct
    45901 ttcttgaaca cccatccgat gaatttttgt tattccatca tcagagaata attcacataa
    45961 agaactgcca attccaccta tctgattgtg gttttctaca gtaaatatag tttttccact
    46021 taacattgtt tttatctgtt ctggtatcgg tttgattcta aataaatcta tcacacctac
    46081 tgaataacct aatttagaca gttcatctgc aactcgaata cttggagcaa ccattatacc
    46141 agaagcaacg attacaagat cttcaccatg tcttaactca atgtagcctt tagaaaaatc
    46201 ttctccacct tgatacacag gaactggagc ttttctaatt gttcgaatat attttagtcc
    46261 ttttaagtct aatgtctggt tcaatatttc acgaaattgg atatcatcag ttgcttcaaa
    46321 aatgatcgat ttaggaatta aacgtaacaa tccaatttct tcaaatggca tatgtgtccc
    46381 accattcatt tctgcagtta ctcctgcatc tgatccaatc acagtggcat ccaattgtgc
    46441 gtatccaaga gaaataaata attgatcaaa tacccttcgt gaagaaaaag gaccaaatgt
    46501 atgaagataa ggtctaaacc cctgaataga caagcctgct gcaaggccga ccatttctgc
    46561 ttccataatc ccaacattca cataacggtc tccaaagtcc ttttcaagat tatgagtagc
    46621 catcgaactt gacaaatcgg cttctaagac tactatatca gaagaacttt gattagcctc
    46681 taaaaggaag tctctatata catgccgtaa ttctttcgta cttctcatca ttctgtttcc
    46741 tccaattcct gacttaatct ttctacaact gaagttaaca tttgtttctc ctctacagta
    46801 gggcgaagat gatgattgga tttcatttct tccagctctt gaaccccttg acctttaata
    46861 gtatctaata caatgcactt aggtgatgaa ttatttgact gttttaattg gacaatccct
    46921 tcataaattt ctctaatatc tgaacccttg accctaatgg attcaaatcc aaatgctgaa
    46981 aatttttcta cgaaatcacc tggattacaa atatcctttg taaaaccatc taattgtttt
    47041 ttgttatcat caacaaatac aattaagttg gataactgtt gatgagaagc aaactgtata
    47101 gcctcccaac attgtccttc atttaactca ccatctccaa caatagcata agtataaaag
    47161 ggactctttc ttattctctg accatatgca agtccagttg caacactaat tccttgtcct
    47221 aaagagcccg ttgtcatatc tatgcctggc gttagatttc tatcaggatg agacggtaat
    47281 ttggttccat ttgtatttaa agaatataag aattctttgt caaagaaacc attcaaatag
    47341 agtgtactgt atagagctgg tcctccatga ccttttgata atatgaaata atctctatct
    47401 cgtgctgcaa atatttctgg agtcattggc attatttcac cataaagcac cgctaaaact
    47461 tctacgatag acagacttcc tccgtaatgt ccgaatccaa gatgattcaa tgttctaaga
    47521 gtatttaatc ggatgttagt cgcaaatttt cttaactcat cttctctatt tttacttaaa
    47581 atcatccctt attcctcctt tgcagatggc tttttaataa aggatactcc aaacataact
    47641 gctagaataa gaacaagacc aatcacaatg cctgcttgtg agccaaattg atttaacatt
    47701 cctaaaataa ttcctgatag accaaaatct gcatctgaga aagttgatcc ttggaaacca
    47761 agtcctccca aaactggcat taaaaagact ggaagaaaac tgattaaaat accttgtaaa
    47821 aatgctccaa tagtggctcc acgaacacca ccagatgcat tcccaatgac acctgcagtc
    47881 gctccacaga agaaatgagg cacaacacct ggtaagataa caaccgttcc tgaagcaatc
    47941 ataattgcca tacttactaa accaccaata aaactagaga taaatccaat tagaactgca
    48001 ttgggtgcat aagtataaac aatcggacaa tccaaagcag gttttgaatt aggtacaaga
    48061 cgctctgaaa tacctttaaa ggctggaaca atttcaccca aaataaggcg aacacctgct
    48121 aaaataacaa atacccctgc tgcaaattga cctgctaatt gtaaagcata aactagacca
    48181 cttgtaccac tactgatttc tttttctata tattctgacc ctgcaaagat agctacaata
    48241 atgtaaataa ctgccataga taaagtgata ctaacagtac tatcacgtaa aaaagctaaa
    48301 ctctttggaa atttaatgtc ctctgttgat tttgatttgt caccgataag gctaccagta
    48361 aaaccactca accaatatcc caaagaactg aaatgaccta aagccacctt gtcatttcca
    48421 gttaattgaa ccatatattt ttgcacaaat gctggggaaa tactcataat aataccgagt
    48481 gctaatcctc ctagtaagat gagaggcaag ctagtaaagc cagcaactga taaaatgacc
    48541 gcaatcatac atgccatata tagagtgtgg tgccctgtta aaaagatata tttaaatcga
    48601 gtaaaacgag cgattaagat attgaacacc atgcctgcaa acataatcag tgcagtagct
    48661 gagccatatg ttgttaaagc tacagctaca attgcttcat tattcggcac aacgccagat
    48721 aaatgaaaag catgctcaaa catggtacca aatggattta aagaattttg tacaattcct
    48781 gcaccaccag atacaactaa gaaaccaaca aaggtcttaa ttccaccttt aataatatca
    48841 ggtaatttct tcttctgaag aactaatcct aaaattgcaa ttaaagctac taaaatagct
    48901 ggtgtactaa caatatccaa tatgaacttc atcataacgc tagcctccta tataagtcct
    48961 ttttcttcac aaagtttagt aattaattct cgtagttcat ccatatcaat aatactattt
    49021 aagatacgaa catctccaag atgactagct gaatcagcta gatcacgacc aacaatccaa
    49081 atatcagctg catttggatc tgctccacct aaatcataat gttcaacttc tacatccgaa
    49141 acattcaaat cactcaatac agattcaata ttcatctgta ccataaaact tgaacctaat
    49201 cctgaaccac aagctgtacc aatttttaac attatctaat cctcctgttt aattatcatt
    49261 ttaatgtcat catagttttt tgatgaaatt aaagtttgaa catgattttt atctcttaaa
    49321 attgttgtta aatgtgacaa agcctttaaa tgactctcat tatcaatggc tgcaatacaa
    49381 atcaacaatc ttacctcttg ttctggatta tccaataaat aaatcggttc ttccaaaact
    49441 aacattgaca ttcctatttc attcacacct tcatctggcc gagcgtgagg aattgctact
    49501 cccttcccta aattaataaa aggtccaaac tcttctactt tttgaatcat tgcctcaggg
    49561 tagttctccg ttatcttatc ttgatccaaa agcggtttag ctgctaaacg aatcgcctcc
    49621 ttccatccta atttttgcga actaacctga taggtttctt tggtaataag ttgttctagc
    49681 actggtacaa tttcctttct atcatttttt tgataaagat aattctttaa cgccaatctt
    49741 aattccaatt cttgtgtaat aattccatat cttttgacaa tattcaggat ttgttcaatc
    49801 tcaaaatctc catactctaa attcggaaaa tcttttaaca ctagttctac tagttgtatt
    49861 gcttgctctt cagtcatcat aaccgaaact agataatttg gcttttctgt ctccaccttt
    49921 atggtagaaa aaaccatatc atagtcacta ctagctttca cctgtaaatc atcaatcttt
    49981 gaggttccta taaactcaat ttgaggaaat aatgctaata gattctcttt taacatcaat
    50041 gaagaactaa caccattagg acaaatgatt gctgctttat accatttttg aggcaaagta
    50101 tctgctttct ttaaataacc tccgaaatgg ataacaaaat atgctgtttc actatcaggt
    50161 atgggattgt caatagcgtc catcaagggc atcaaagaat ctttgactaa ttcaaataaa
    50221 tcaggataat gttctttaac atgcaataca tattcatttg aactaggtag gccgaacttt
    50281 aatctatagt aagccggtat aaggtggcga cgaagatttt ctctcaatcc ttccctttgt
    50341 ttaaaatgta acaaagaaat atcttccatt ctacttataa tagcctctgt taattgatta
    50401 aagtaaaccg gagcaacatc tacttcacct tcaaagcaac ttgataataa aactgtgata
    50461 tagcgataat catcctcaga aaacaccgta tctataattc ccaaatcaac cactgtatcc
    50521 aataaaatag tcgttatatc ttgaataaca ggagatacta atgtctctga aagacatact
    50581 ctttcaacat ccctttgata cctacacaga atgaatacta aaccgaaaag gtaaactttt
    50641 aattgattaa caataggtac tagctgtagc ttctcataat aatctttaac tacctgatca
    50701 atcaaatcat aagttaatga atatccccaa ctggataaaa cataatccaa accccaaatc
    50761 cctatggagg attccagcaa ctcactaacc atttgaaaag ctaaacggtg cttattccac
    50821 tctgaaccgt gtaaagtata accttttgct ctactgtacc ctagctccaa atcattatct
    50881 aacataatct ttcttaatga ttgaatatca gataaggttg tattcttact tactttcaaa
    50941 aagtcttggt aatgattatt cgatataaaa tctaatcggc aaaaagtgta aagatagatt
    51001 aaagctaagc gagtcgactt tggtaaaacc aattcatccg acttaataat atctgtcaaa
    51061 gactgcttcg tacgatttga taaactatag cgaccttgtt ttttatccag cactatccct
    51121 ttattagcta gataaggcac taaataatct attccttctt tgacttcctt tataggtaag
    51181 ctcaccttaa cagataattc atataatgat agctcacaat gatccatcaa agtcatcaaa
    51241 ataactagtg ctctataatc aaacatttct cttcctttct aactacaatt atagtgtaaa
    51301 aattataaga ataaaagagt atttgagcac aatataatct caccttttaa aagaaattat
    51361 tgggctgaaa gtttttagta attattttca actttctatt gacttttaaa aacaaagtga
    51421 tatcatttag atatcaaata atgggaggtc attcttatga ctgaaaaact aatcaattca
    51481 aaaccaaatg gtgtattcgc attgattctc attgagttga caatcgtact tggtatcttt
    51541 atatttataa tgggtgttgg ttcggaaaac atttttggaa ttattatcgg acctttacta
    51601 atcgtaattg caggtctagc tcatgctggt ttaaaagttg tcaaacctca ggaagctctg
    51661 gttctgacac tctttggtaa ttatacaggt accatcaaag aacctggttt ttactttgtc
    51721 aatcccttca gcgtagcagt caaccctgca aaccacactc gacttggaca aagtggtgat
    51781 gttagcacaa aatctccttt tttaggagct aaatcatcaa atgacaatga tgtaaatctt
    51841 gaaattggca agaaacagat ttccctcaaa gtcatgacct tgagcaattc tcgtcaaaaa
    51901 atcaatgatt gcttaggaaa ccctgtagaa atcggtatcg cggtaacttg gagagttgtc
    51961 gataccgcta aggcagtctt caacgttgat aactacaaag aatatctttc attgcaatgt
    52021 gatagcgccc tccgtaatat tgtccgcatc tatccttacg atgtgtctcc taatgtggat
    52081 actacgggtg acgggcaagc agatgaaggt agtctccgtg gctctagcga aattgttgct
    52141 aaccgtattc gtgaggaaat tcaaagtcgc gtagaagatg ctggcttgga aatccttgaa
    52201 gcacgtatca cttacctagc ttatgctcca gaaattgctg ccgttatgct tcaacgccaa
    52261 caagcatctg ccattattga tgcacggaag atgattgtag atggtgctgt aggaatggtt
    52321 gaaatggcac tagaacggct caatgaaggg gaattagtag aacttgacga agaacgaaaa
    52381 gctgccatgg tttcaaatct ccttgtcgtt ctttgtggca atcatgatgc acaaccaatt
    52441 gtcaacacag gaagtcttta ctaaagatgt ctgaagctaa aaaaaagcag atcccccttc
    52501 gactctcaac aaagttatac gctgcactcg catcatgggc agaagacgac tttcgttcag
    52561 tcaatgggca aatcgaatat ctcctcacag agtgtgtcaa gcaacggaag aaagacggaa
    52621 aatacgtatc agaaaccatt gacgaaccat ttgagattga tatttaacac cttctcctgt
    52681 ctgccgtgtc ggataggaga attttttcat ctttttttgt caagtaactt tactttacaa
    52741 aaaaaatgtg ttatcctaat atggttgatg aaaatcagta gattgaatcg aatataaata
    52801 cctaaaggag aaatcaaaat ggcagtacct gcacgtcgca cttcaaaagc gaagaaaaac
    52861 aaacgtcgta cacactacaa agtaacagct ccatctgtaa actttgacga aactactgga
    52921 gattactcac gttctcaccg tgtatcactt aaaggatact acaaaggacg taaaatcgct
    52981 aaagctgcat cagctgaata atagaaggga gataccatgc gcgtaaatat tacacttgaa
    53041 cacaaagaat ctggtgaacg cttgtacctt acttctaaaa acaaacgtaa cactccagac
    53101 cgccttcaat tgaagaaata ctcaccaaaa cttcgcaaac acgttgtgtt tacagaagtg
    53161 aagtaagcat tcaatacgaa tcaatacaga agaaaaacgc ttgatcagcg ttttttcttt
    53221 ttgttaattt cactatattg caagggaaat cattcgaatg actacatttt ttgaaataag
    53281 aatacggatt cggacgatta aaagtaagag aaactcaaat gtaagttggg gttccttttt
    53341 tgtatatttt tcaaataacg cctctacact atttgtagca aattcaccaa ctacagttgc
    53401 atcttagtta aaataagtta gaatatgtaa gtgagtacca gatataccaa gacatcgtca
    53461 ccatctaagg tatattcaaa atacaaaagt tgaccaacta gatttctgaa tatccttata
    53521 tatccattct taaaattggt ttaaatagcg tagtctttta aactagtttt gagaatccaa
    53581 aaaatcttcc tacatatgta agaagatttt ttagttcaga atgattagat ttagctaatg
    53641 gatacctatc ctacccactc accgttagca ttgactcgat agccatcggg tgtagtcgtg
    53701 tttactaata aatctcctga attataggta tagtaccatt taccagaaac tgtaaaccaa
    53761 ccagtagcca ttgaacctga ttcatttaag taataccata agcctttgtc tttaac
//
LOCUS       DAVHSY010000010        52162 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.010, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000010 DAVHSY010000000
VERSION     DAVHSY010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.010"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            370..1506
                     /gene="lctO"
                     /locus_tag="VVR43_000763"
     CDS             370..1506
                     /gene="lctO"
                     /locus_tag="VVR43_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU6149155.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      1758..1846
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            2062..2730
                     /locus_tag="VVR43_000764"
     CDS             2062..2730
                     /locus_tag="VVR43_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU6149156.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            2967..3749
                     /gene="thiM"
                     /locus_tag="VVR43_000765"
     CDS             2967..3749
                     /gene="thiM"
                     /locus_tag="VVR43_000765"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU6149157.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEIAEKRPNGHLPGTFKAEFINALYEITDEDVKEFKRVK"
     gene            3751..4380
                     /locus_tag="VVR43_000766"
     CDS             3751..4380
                     /locus_tag="VVR43_000766"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU6149158.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      4589..4677
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4939..5499
                     /locus_tag="VVR43_000767"
     CDS             4939..5499
                     /locus_tag="VVR43_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6149159.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            5500..6885
                     /locus_tag="VVR43_000768"
     CDS             5500..6885
                     /locus_tag="VVR43_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149160.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLSHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            6887..7537
                     /locus_tag="VVR43_000769"
     CDS             6887..7537
                     /locus_tag="VVR43_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU6149161.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSLANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            7548..8240
                     /gene="tenA"
                     /locus_tag="VVR43_000770"
     CDS             7548..8240
                     /gene="tenA"
                     /locus_tag="VVR43_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU6149162.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFYISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            8245..8769
                     /gene="thiW"
                     /locus_tag="VVR43_000771"
     CDS             8245..8769
                     /gene="thiW"
                     /locus_tag="VVR43_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU6149163.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFHYSALGE
                     ILGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            8769..9572
                     /locus_tag="VVR43_000772"
     CDS             8769..9572
                     /locus_tag="VVR43_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU6149164.1"
                     /translation="MQEFTNPFPIDSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEAYE"
     gene            9565..10197
                     /locus_tag="VVR43_000773"
     CDS             9565..10197
                     /locus_tag="VVR43_000773"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU6149165.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(10405..11196)
                     /gene="thiD"
                     /locus_tag="VVR43_000774"
     CDS             complement(10405..11196)
                     /gene="thiD"
                     /locus_tag="VVR43_000774"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU6149166.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(11280..11378)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            11562..11957
                     /locus_tag="VVR43_000775"
     CDS             11562..11957
                     /locus_tag="VVR43_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU6149167.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKFFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            11968..12339
                     /locus_tag="VVR43_000776"
     CDS             11968..12339
                     /locus_tag="VVR43_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU6149168.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEIMPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            12349..14592
                     /locus_tag="VVR43_000777"
     CDS             12349..14592
                     /locus_tag="VVR43_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU6149169.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLVISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            14799..16574
                     /gene="spxB"
                     /locus_tag="VVR43_000778"
     CDS             14799..16574
                     /gene="spxB"
                     /locus_tag="VVR43_000778"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU6149170.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            16685..17032
                     /locus_tag="VVR43_000779"
     CDS             16685..17032
                     /locus_tag="VVR43_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6149171.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(17149..18195)
                     /locus_tag="VVR43_000780"
                     /pseudo
     CDS             complement(17149..18195)
                     /locus_tag="VVR43_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            18260..18556
                     /locus_tag="VVR43_000781"
     CDS             18260..18556
                     /locus_tag="VVR43_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU6149172.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGVLKRSKKKSFYWYKDVIDSNGASIE"
     gene            18677..19621
                     /gene="manA"
                     /locus_tag="VVR43_000782"
     CDS             18677..19621
                     /gene="manA"
                     /locus_tag="VVR43_000782"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU6149173.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDTLLTKVPVKAG
                     DFFYVPSGTMHAIGTGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(19642..20973)
                     /locus_tag="VVR43_000783"
     CDS             complement(19642..20973)
                     /locus_tag="VVR43_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEU6149174.1"
                     /translation="MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALVAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMMP
                     LLFIVLPQLFDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILG
                     ILTFVFGIPSALSYGVMADVHIFGKIFFDAMDFLASNLLMPFGALYLSLFTGYIFKKA
                     LAMEELHLDERAWKQGLFQVWLFLLRFFVSSFQSSSLWSSLPNLCNQKGLE"
     gene            21056..21810
                     /locus_tag="VVR43_000784"
                     /pseudo
     CDS             21056..21810
                     /locus_tag="VVR43_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(21830..22285)
                     /locus_tag="VVR43_000785"
                     /pseudo
     CDS             complement(21830..22285)
                     /locus_tag="VVR43_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
     gene            complement(22305..23480)
                     /locus_tag="VVR43_000786"
     CDS             complement(22305..23480)
                     /locus_tag="VVR43_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU6149175.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(23539..24384)
                     /locus_tag="VVR43_000787"
     CDS             complement(23539..24384)
                     /locus_tag="VVR43_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU6149176.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            24509..25066
                     /locus_tag="VVR43_000788"
     CDS             24509..25066
                     /locus_tag="VVR43_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU6149177.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            25085..25552
                     /locus_tag="VVR43_000789"
     CDS             25085..25552
                     /locus_tag="VVR43_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU6149178.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            25641..26270
                     /gene="upp"
                     /locus_tag="VVR43_000790"
     CDS             25641..26270
                     /gene="upp"
                     /locus_tag="VVR43_000790"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU6149179.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            26444..27034
                     /gene="clpP"
                     /locus_tag="VVR43_000791"
     CDS             26444..27034
                     /gene="clpP"
                     /locus_tag="VVR43_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU6149180.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            27113..27361
                     /locus_tag="VVR43_000792"
     CDS             27113..27361
                     /locus_tag="VVR43_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU6149181.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            27463..28623
                     /locus_tag="VVR43_000793"
     CDS             27463..28623
                     /locus_tag="VVR43_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6149182.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            28891..29760
                     /locus_tag="VVR43_000794"
     CDS             28891..29760
                     /locus_tag="VVR43_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU6149183.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            29764..30720
                     /locus_tag="VVR43_000795"
     CDS             29764..30720
                     /locus_tag="VVR43_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU6149184.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            30720..31484
                     /locus_tag="VVR43_000796"
     CDS             30720..31484
                     /locus_tag="VVR43_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149185.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            31484..32194
                     /locus_tag="VVR43_000797"
     CDS             31484..32194
                     /locus_tag="VVR43_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149186.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISNRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            32608..33264
                     /locus_tag="VVR43_000798"
     CDS             32608..33264
                     /locus_tag="VVR43_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU6149187.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNYQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            33372..34467
                     /gene="prfB"
                     /locus_tag="VVR43_000799"
     CDS             join(33372..33443,33445..34467)
                     /gene="prfB"
                     /locus_tag="VVR43_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU6149188.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            34485..35177
                     /gene="ftsE"
                     /locus_tag="VVR43_000800"
     CDS             34485..35177
                     /gene="ftsE"
                     /locus_tag="VVR43_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU6149189.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            35170..36096
                     /locus_tag="VVR43_000801"
     CDS             35170..36096
                     /locus_tag="VVR43_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6149190.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLRI"
     gene            36382..38562
                     /locus_tag="VVR43_000802"
     CDS             36382..38562
                     /locus_tag="VVR43_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU6149191.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTLFGGSIKVADYFISVMEAPALNMGVFVGIISGFIGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSIIAAIVLAAFWPVVQTGINSFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVLTGAAKGSQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVVVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFVATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEESSNEVKVAAGSQAVNIINLLGGRANIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADVLKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKGLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHALGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVVAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            38614..39429
                     /locus_tag="VVR43_000803"
     CDS             38614..39429
                     /locus_tag="VVR43_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU6149192.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEI
                     TSPEVEVNDLYQALPAAELIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            39569..40912
                     /locus_tag="VVR43_000804"
     CDS             39569..40912
                     /locus_tag="VVR43_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6149193.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKIVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            41289..42479
                     /locus_tag="VVR43_000805"
     CDS             41289..42479
                     /locus_tag="VVR43_000805"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU6149194.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            43032..43967
                     /locus_tag="VVR43_000806"
     CDS             43032..43967
                     /locus_tag="VVR43_000806"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU6149195.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            44001..45038
                     /locus_tag="VVR43_000807"
     CDS             44001..45038
                     /locus_tag="VVR43_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU6149196.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            45179..45784
                     /locus_tag="VVR43_000808"
     CDS             45179..45784
                     /locus_tag="VVR43_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU6149197.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            45941..46471
                     /locus_tag="VVR43_000809"
     CDS             45941..46471
                     /locus_tag="VVR43_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU6149198.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            46492..47394
                     /locus_tag="VVR43_000810"
     CDS             46492..47394
                     /locus_tag="VVR43_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HEU6149199.1"
                     /translation="MKPSIHSLAHQTMQKWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFADEGVQVNLAVSLHA
                     PNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAE
                     LLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGTDID
                     AACGQLRFNTMKRDRQKAVAAVNP"
     gene            47394..47876
                     /locus_tag="VVR43_000811"
     CDS             47394..47876
                     /locus_tag="VVR43_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU6149200.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKVRN
                     "
     gene            47878..49419
                     /locus_tag="VVR43_000812"
     CDS             47878..49419
                     /locus_tag="VVR43_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6149201.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(49475..50278)
                     /locus_tag="VVR43_000813"
     CDS             complement(49475..50278)
                     /locus_tag="VVR43_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU6149202.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(50362..50574)
                     /locus_tag="VVR43_000814"
     CDS             complement(50362..50574)
                     /locus_tag="VVR43_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149203.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            complement(51053..51262)
                     /locus_tag="VVR43_000815"
     CDS             complement(51053..51262)
                     /locus_tag="VVR43_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149204.1"
                     /translation="MLSVNTILEKFYKKHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            51432..51704
                     /gene="rpsP"
                     /locus_tag="VVR43_000816"
     CDS             51432..51704
                     /gene="rpsP"
                     /locus_tag="VVR43_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU6149205.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            51724..51963
                     /locus_tag="VVR43_000817"
     CDS             51724..51963
                     /locus_tag="VVR43_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU6149206.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
BASE COUNT        15710 a         9671 c        11362 g        15419 t
ORIGIN      
        1 aaaaaattaa taagtgggat aggaagttag cgtcaactag gatagtatct tgcttaaaca
       61 gtatatatgg gactgatata agtccatagg tcctattaga ggatgttctg gtgtcttatt
      121 cacttgtttt tttatagtat tagtagatag aatcagcaaa taaaaaagta gttcaaatgc
      181 ctggcagcaa aaaatctcaa cgattcactt aatatagact aaagtttaga gtttaaggaa
      241 agtagggcta gtatattgta tgaaaaaata agatggtttt taagcaaaac tcttgaaaat
      301 gattgaaaaa agagttatta tagttgtgta gtaaaaagca aacgcttact taatcaagga
      361 gggcatttta tgtcatacaa aacaagcaat gcagaaggtc atgtagactt catcaatacc
      421 tatgatttgg agccaatggc gcaacaagtt attcctaaag cagcatttgg ctatatcgct
      481 agtggggcgg aagatacttt cactttaaga gagaatatcc gcgcctttaa ccacaaactc
      541 atcgttcctc atacactttg cgatgttgaa aatccaagta cagagattga atttgcaggt
      601 gaaaaactat cttcaccaat cattatggcg cctgttgcgg ctcataaatt ggcaaatgaa
      661 cagggggaag tggcgactgc gcgtggtgtg catgagtttg gttctcttta tacaaccagc
      721 tcttactcta ctgttgacct tccagagatt tctgaagccc ttcaagggac accccattgg
      781 ttccaatttt actttagtaa ggatgacggt atcaaccgcc acatcatgga ccgtgtgaag
      841 gctgaaggtt ataaagcgat tgtcttgacg gcagatgcta ctgtaggggg gaatcgtgaa
      901 gtggataagc gtaatggttt tgtcttccca gttggcatgc cgattgttga agaatacctg
      961 ccagaaggtg ctggtaaatc aatggacttt gtttacaaat cagctaaaca acgcttgtct
     1021 ccacgcgatg tagaatttat cgctgaatac tctggtcttc ctgtgtatgt caagggacca
     1081 caatgccgtg aggacgttga acgttcactt gctgcaggag cttctggtat ctgggtaacc
     1141 aaccacggtg gtcgtcaaat cgacggtgga ccagctgcct ttgactcgct tcaagaagtg
     1201 gcagaagcag ttgatagacg tgtgccgatt gtctttgact ctggtgttcg tcgtggtcaa
     1261 cacgtcttta aagccttggc ttcaggagca gacttggtag ctattggtcg ccctgttatt
     1321 tatggcttgg ctctcggtgg tagtgtcggt gtgcgtcaag tctttgaaca cttgaatgcg
     1381 gaattgaaga cagttatgca attgtctgga gctcagacca ttgaagatgt caaacacttt
     1441 aagctccgtc acaatccata caacccaacc ttcccagttg accctcgtga cttaaaattg
     1501 tattgataaa acagattgcc tccactgaat gtggaggttt ttcttcgtgt attggaagaa
     1561 taaatcgcta tcgaaaacta taataaaatg aaataagaat aggacaaatc aatcaggaca
     1621 gttaaatcga tttctaacaa tgttttagaa gtagaggtgt actattctag tttcaatcta
     1681 ctatataaag atatttttcg gtcaaatatc ttgctagggc tttcattttt tgctatactg
     1741 gttcagtaat taaataatag agacatttgg ggtgctttaa gctgagatga tacccattga
     1801 acctgataca gttaagactg gcgaagggaa atgtgaaacg ttttttcgta tggcgaaatg
     1861 aacgatctaa tcttgtaagt caactctaat tcttgattgt aattggagtt ttttgtttat
     1921 ataaactgga taggcttgtt tagttagctt ctctgcaaat gctctcgatg tgctttaaaa
     1981 ggatcaagtg gaattacgat tttgcttgat atttcttggt gttttattaa ttactaacaa
     2041 gtaaagagag gagaagtaaa tatggaaaca caagactatg catttcagcc aggtttgact
     2101 gttggagaat tattaaaaag cagtcagaag gattggcagg ctgcaatcaa tcatcgtttt
     2161 gttaaggaac tttttgcggg gacaattgag aataaggtct taaaggacta tctgattcaa
     2221 gattatcact tctttgatgc cttcttatcc atgctgggtg cctgcgtagc tcacgcagat
     2281 aaacttgaat ctaagcttcg ttttgccaag caactaggct ttcttgaagc agatgaagat
     2341 ggttatttcc aaaaggcttt taaagagtta aaagtagcag agaatgacta tctagaagtg
     2401 actttgcacc ctgtaacaaa agcctttcag gatctaatgt attcggcggt ggcttcatca
     2461 gactatgccc atcttttggt catgctggtc attgcagaag gtctctattt agactggggt
     2521 tctaaagatt tggctttacc tgaagtctat attcattcgg aatggatcaa tctccacaga
     2581 ggtcctttct ttgcagagtg ggttcaattt ctggttgacg aactcaatcg tgtcggtaaa
     2641 aatcgagaag atttgacaga acttcagcaa cgctggaatc aagcagtcgc tttagaatta
     2701 gctttttttg atattggtta cgatgtctag agaaggctca tgatatttac aaatttgatg
     2761 aggtaagact cttcgaaaat ctcttcgaac cacgtcagtt ctatccacaa cctcaaaaca
     2821 gtgttttgag caacctgcgg ttagcctcct agtttgctct ttgattttca ttgagtataa
     2881 atcattcaat gtaaatgaaa aaaattctca actaaagata aatcgaaatc agtagatcgt
     2941 ataaagtgaa aaggaaggat ttcaatatga caagtttaaa attattaaaa gaaaaagcac
     3001 cattggtcat ttgtataacc aatgatgtag taaaaaattt cacagcaaat ggattagtag
     3061 cactgggcgc ctcaccagcc atgagtgagt ttccagcaga tttagaggat ttgttaaagt
     3121 atgctggtgg tttattaata aacataggaa cattgacaga tgaaaattgg aaattatacc
     3181 aagctgctct gaaaattgcg gagaaatata atgtcccagc agttttagat cctgtagcct
     3241 gtggagcagg agaatataga aaaaaagtag cagatgatct aatcaacaat tataaactag
     3301 cagcgattag aggaaatgct ggcgagattg cctctttagt aggaatagat gtggcatcta
     3361 aaggagtaga tagtgcgggc gtagataata ttgacgaaat tgctctagca gcaaatgaga
     3421 agttcaatat tccaatagta gtaacaggtg aagtggatgc cattgctgtt aatggagaag
     3481 tggtaacgat tcataatggt agtgctatga tgccgaaagt cattgggaca ggatgcttat
     3541 taggagctgt agtagcaagc tttatcggac tggaaaaagg tcaagaattg aaatcattag
     3601 aaacagcaat gttggtttac aatatcgctg gagaaatagc agaaaaacgt cccaatggac
     3661 atcttcctgg aacatttaaa gctgaattta taaatgcctt atacgagatt acagatgaag
     3721 atgtaaagga attcaaaaga gtgaagtaag atgtttcata aagaattact aaaactatat
     3781 tttatttgtg gaacgactac ttgccaagga aaaaatctat atacagtcgt tgaggaagcc
     3841 ttaaaaggtg gtataacctt atttcaattt cgagaaaaag gtgagggtgc tttagaaggc
     3901 ttagaaaaac ttgagctagc tatccaaatt aaagaacttt gtaaaaaata caatgttcca
     3961 tttatcgtta atgacgatat agatttagca atggaaattg acgccgatgg cgtacatgta
     4021 ggtcaagatg atattggtgt tgatgaaatt agaaaattga tgccagataa aataattggt
     4081 ctttctataa gaaacgaaga agaatttcaa caatcaaaag ttgaatatgt agattatgta
     4141 ggtgttgggc ctgtatttga tacccagtca aaagatgatg ctggtggtgc tataggttat
     4201 gaaggtcttg aattgatgag aaaactattg ccacaaatgc ctttagttgc aattggtggg
     4261 atacagacga aacatattaa agacattata aagaccaatg ttgacggcgt ttcaatcatt
     4321 tcggcaatat cgtatgcaaa aaatatagaa aaaactgttc gggaaatgag tgaacaatag
     4381 atatctatcc ttggattcta agtaagtagg attttccttt tttaaaaagc tatgtctaga
     4441 ttcagcttga atggctaatt catcaaacag gtcatttgtt ttttgcaaaa gaaagatctg
     4501 ctgtctttgt gagtgcaagg ctgtatttcc agttcaattt cttgaactag tataaaatgt
     4561 gtgttataat aatcacataa ttaaataata aaggcatttg gggtgcttta ggctgagatg
     4621 atacccattg aacctgatac agttaagact ggcgaaggga aatgtgaaat gtttttttcg
     4681 tatgtcgaaa agaactgtct aatcttgtaa gctgaactct aattcgtatc tgtaattaga
     4741 gttttttctt ttacgaaact ggatgaagat gatatagtag attgaaataa gatgcgaaca
     4801 aatcaattag aaaattcaaa ttaatttcta gaaatatttt agcattcctg tgtactgttc
     4861 taaattcaat ctgctataca aagtatttag gtcggtcttc ttgagtgccc cacttttctt
     4921 ttaaaaaagg agttttttat gttgaaaaaa tggcagttaa aagatgttat cttgcttgct
     4981 ttcttgtcta tcttttttgg tggggttttc gttggttcag gatatgtgta taatattctc
     5041 agtctactct taacacctct tggtttgcag gcctttgcca atgaaatcct cttcggtctc
     5101 tggtgtatgg ctgcgcccat tgctgccatc tttgttccga gagtcggaag tgcaacgatt
     5161 ggagaagtgc tagctgcgct tgctgaagtc ctttatggta gccaatttgg tctaggagct
     5221 cttttgtctg gcttagttca aggtttggga agtgaatttg gttttatcgt aactaagaat
     5281 cgctatgaaa gttggctctc tctaactgct aatagtattg ggattacgct tgttagcttt
     5341 gtctatgaat acattaagtt aggttactac gccttttccc ttccgtttgt cctttcctta
     5401 cttgtggtac gttttatttc tgtttatttc ttctgtacca tcttggttcg tgccattgtc
     5461 aaactctatc atcagtttgc aactggagga aaagcataga tgggtctgga actacgagcg
     5521 attcagtccc caatcttctc tgagccgttt gattttactt ttcatgcgca agcctttacc
     5581 ttgttagttg ggagcagtgg ttcaggaaaa tccagccttt ttcaagtcat tgcccaagtc
     5641 agttctcttc cctatagtgg tcaagtcctg atagatggga gcgaggtcag tcagctttct
     5701 atcatcgcac gtgtccagaa ggttggcatt ctctttcaaa atcccaatca tcaatttacc
     5761 atggagaact tgtttgagga gctgattttc accttggaga atatcggcta tcaccttcag
     5821 gaaattgatt ctaaaatagc agaggttgtc cagcaatgtc gttgcgaggc aatcttacac
     5881 cgtcccattc atcacctatc aggtggggaa aagcaaaaag cagcgctggc tgtcctcttt
     5941 gccatgaatc ctagggtcta tctcttggat gagcccttcg cttctattga ccgcaagagc
     6001 agaatcgaga tattggagat tctaaaagag ttggctcttg atgggaagac agttattttg
     6061 tgcgaccatg atttatctga ctataaagcc tatatcgacc atatggttga gctaagagac
     6121 ggaaaactaa gggaagtgtt tcaaatccct tcctatgaga tgacacaggt tgcttcaaag
     6181 gaagttgctt ctagcccgga actattccat atgaaccgtg tgactggtga gcttggtaat
     6241 cgccccctct tttcaattgc tgatttcaca ttctatcaag ggatttcctg tatcctgggt
     6301 gacaatggtg tcgggaaatc aaccctcttt cgctctattc ttcaatttca aaagtataag
     6361 gggcgcattg catggaaggg gacagtcctg aaaaagaaaa agagtttgta ccgtgatctg
     6421 acgggtgttg ttcaggaagc tgagaagcag tttatccgag tcagtctgcg agaggagctt
     6481 caattagatg gacctgattc tgaaagaaat cagcggattt ttcaagcttt acgatatttt
     6541 gatttggagc aggcagtcga taagagtccc tatcaattaa gtggtggtca gcaaaaaatt
     6601 cttcagctcc tgaccatctt gaccagtaag gcttccgtga tcttgctaga tgaacctttt
     6661 gcaggtttgg atgatagagc ctgccattat ttttgcaagt ggattgtgga ggagaggaat
     6721 caaggaagaa gttttctgct cattagtcat cgtttagacc ctttgatttc tgtggttgat
     6781 tattggattg agatgactag tcaggggctc agtcatgtga aagaagtgac cattaccaaa
     6841 ccacttacat ctcagagtag caatacccaa ggggaggtga gatagtatgg tcaaagtagc
     6901 aacccagaca ccgattatca gtctcttctt gctgatttta tccttggaaa catctttcat
     6961 tccttcgatt gctctgaatc tttcggtagt cgcattttgt attctcttta tgctctatta
     7021 ccgtcgattt aaaatgttag cttggatgat catacttgcc attttaccat ctttggccaa
     7081 ctactgggca gttcagttac acggagatgc ttcacaggca gtcatgcttg gaacgagggc
     7141 ctttgtgaca gtttgtatcg gccttgtctt tgtttcctct atttcactaa aagagcttct
     7201 cttgtacttg gctcaaaagg ggctatcacg ctcttggtcc tatgccttga ttgtggtatt
     7261 caattccttt cctctcattc agcaagaaat caagtccctc aaagaagctt gcctattacg
     7321 tggtcaagaa ctgcattttt ggtcgccctt gatttacagt aaggttctga tgacagtctt
     7381 taggtggcgc catctttacc tgagagctct gtctgctcat ggatatgacg aacatgcaca
     7441 gttgaagaat agctatcgga ctttttatat tcctaaaaaa acaaaattaa tctacctgct
     7501 tttcttttta ttgcttcaaa ccagtctatt tttataaagg agttattatg gaatttacag
     7561 atattgcgat ggaattatcc aagaaagctt ggcaggcttc ctttcatcat ccctttattt
     7621 tacaattaca agaggggaat ttagaacctg ccattttccg ctattacctg attcaggatg
     7681 cctactatct gaaggccttc tcagaaatct atcatctttt ggctgataag acttcaaacc
     7741 aagagatgaa aagactcttg aaacaaaatg ctcagggttt agtggagggt gagttattta
     7801 ttcgccaaca atttttcaag gaaatggaaa tcagcgacca ggaaatggag caacatccaa
     7861 ttgctccaac ctgttatcat tacatttctc atatttatag gcaatttgca gaaccgaact
     7921 tagccatcgc ttttgcaagc ttgcttcctt gtccttggtt ataccatgat ataggcaaat
     7981 cacttaatct taaaccatca ccaaatcctc tctatcaaca atggattgaa acttatatta
     8041 cggatgagtt agagcaacag atcagagagg agggagcact ggtcaatcag ctctatcgag
     8101 aaagtgacga gacagacaag caaaaaatgc tagatgcctt ctacatcagt gttcatatgg
     8161 aagccaagtt ttgggaaatg gcctaccaac accagacatg gaagagcgat ttacagtctt
     8221 tagaaaaagg agaagaatag aagcatgaga aagcaccaat tacaagttca caaattaacc
     8281 attttatcta tgatgattgc ccttgatgta gtccttacac ctatctttcg aattgaggga
     8341 atggcaccga tgtccagtgt agtcaatatt ctagcgggaa tcatgatggg acctgtttat
     8401 gccttggcca tggctacagt cacagccttt atccgtatga cgactcaagg gattccgcct
     8461 ttagctctca caggagcgac ttttggagcc cttctggcag gtctctttta taagtacggt
     8521 cgaaaatttc actattctgc tctaggagag attttgggaa caggtattat tggttctatt
     8581 gtttcctatc ctgttatggt gctctttaca ggatcagctg ctaagcttag ctggtttatc
     8641 tacacgcctc gatttttcgg agcaaccttg attggtacag cgatttcctt tattgccttt
     8701 cgatttttaa tcaagcagga attctttaaa aaagtgcagg gatatttctt tagtgaaagg
     8761 atagactgat gcaggaattt acaaatccct ttcctataga ctctagttcc ctcattcact
     8821 gtatgaccaa tgagatttct tgtgagatgc tggcaaatgg gattttggct ctgggatgca
     8881 aacctgtcat ggcagatgat ccccgtgagg ttcttgattt tactaagcaa agtcaggctc
     8941 tcttcatcaa tttggggcat ttgtcagctg agaaggagaa agcaatccgt atagcagctt
     9001 cttatgcagc tcaagtttgt ctcccaatgg tagtagatgc ggttggcgta acgacttcat
     9061 ccattcgtaa gagcttagtt aaagaccttt tagactatag acctacggtc cttaaaggaa
     9121 acatgtcaga aattcgaagt cttgttggat taaagcacca cggcgttggg gtcgatgcga
     9181 gtgctaaaga tcaagaaacg gaggatttgc ttcaagtctt gaaagactgg tgtcagacct
     9241 atcctggtat gtcattctta gttactggcc ccaaggacct catcgtttcg gagaatcaag
     9301 ttgctgtact ggagaatggc tgtactgaat tagactggat aacagggaca ggagatttgg
     9361 ttggagcctt aacagccgtt tttctcagcc aaggaaagac tggttttgaa gcttcttgct
     9421 tagcagtctc ttatctcaat atcgctgctg agaaaatagt tgttcaagga atgggattgg
     9481 aagaatttcg ttaccaagta ctcaatcagc tttcgctcct aagaagagat gaaaattggc
     9541 tagataccat caaaggagag gcttatgaat agagaagcac ttagactata tctggtaacc
     9601 aatcgctatc aagattccgt ggaaagcttt cttgcaaaag ttgagacggc ctgccgttca
     9661 ggggttacca tagtccaatt gcgagaaaaa aatctcacaa ccaatcaata ttatcaactg
     9721 gcaaaacaag tcaaggaaat aacagatgct tatcaggtac ccttgataat cgatgatcgg
     9781 ttggatgttt gtcttgcggt tgatgctgct ggtctgcata ttggagatga cgaactccca
     9841 gtttcggttg cccgacaagt cttgggtcct gaaaaaatcc tcggtgtcac cgctaaaacg
     9901 gttaaaagag ctctggaagc ggagaaatca ggtgcagatt acttggggac aggagccatt
     9961 tttccgacaa ccaccaagga aaatgcaccc atcaccctga tttcaacctt gaaaacaatt
    10021 tgccaaacgg ttgccattcc aatagttgct attggcggct tgacttcgga gaatattgat
    10081 cagcttatgg gcactggcat agctggtgta gctgttgtac gtgatttgat gcaagcagaa
    10141 gatattgagg caaaaacgca agccttttta acaaagttgc atgacattct ttcctaatta
    10201 atactcaatg aaaatcaaag agtaaactag aaagctagtc gcaggttgct caaagtactg
    10261 ccttgaggtt ttagataaga ctgacgaagt cagctcaaaa cagtgttttg aagttgcaga
    10321 tggaagctgg cgtagtttga agagattttc gaagagtata aaaactctct aattccctta
    10381 aagtgggaac tagagagttt tttcttaatc tttaaaagtt gtatggttga ctggaccaga
    10441 accatgaccg agttgagggg catcttgaat agcttttgtg ataaaggcct tggccttatc
    10501 aactgcctgg taaagactct tgcccttggc tagttcagca gtaatcactg cagcaaaggt
    10561 acatccagta ccatgggtgt gacaggtttg aattcgtggg ctttcccaga caaattgttc
    10621 attcttggta aagaggaaat ctttagcacc acctttgaga tgtccgcctt tgataaccac
    10681 agactgagga ccaaattctt ttaaaatcag gcgaccagca cgctgcatgt cttcggggtc
    10741 atggattgaa aaaccaacaa tctcttctgc ttcaggaaga tttggcgtaa taatagttgc
    10801 tagaggtagt aagtttgttt tgagatagtc tctagcattt gagtcaatca aggcatctcc
    10861 acttgtagca accataacag gatcaaggac atagggacaa tccagttttt taagataggg
    10921 ttggatgatt tccatgattt cagtagtagc caacattcca gtttttacag cctgaggtgg
    10981 aatatcagaa aagacactct ccaattgggc tttcaacatt tgaggagaaa cgtgctcgat
    11041 tagctgaaca cctctggtat tttgagcgac aagactggtt acaacagcca ttccatagac
    11101 atctctcgct tggaatgact ttaaatctgc cataatgcca gcaccaccac tagggtcagt
    11161 ccctgcaatg gtcaaagcaa cgggtaaata agtcatctaa aacctcccaa ccaactgaag
    11221 tttgtattct taagaacaag ctagtctgtt ttagaaaggc aatagaagac tgctagtccc
    11281 cattatcatt tccacttcca tcagctagca ttacctagat tgagtcagag ggatctaaca
    11341 gtcgttaatc tcagctttac gcacccctag tggttgtttt cttttttctt tagtatagca
    11401 tatttttatt gtttatatag taatatttga ctgcaaatcg tttttcaaat gattaaaatt
    11461 ctatttttcg aagaaaatat tatttctata attgacaaat gtagattttg ggagtatact
    11521 gttgagtgta attgacaaat gtagattttg gaggtatggt aatgcagatt tcagatgcag
    11581 aatggcaggt catgaagatt atttggatgc agggggagca gaccagtaca gatttaatta
    11641 gggttttggc agagcggttt gactggtcca agtccacggt tcagacactt ttggctcgtc
    11701 tagttgagaa agagtgtttg actcggaaaa aagaaggcaa gttctttgtt tattcagcgc
    11761 ttttaactct agaccaaagt cgggatttac ttgtccaaga tatcaaagac aaggtttgtt
    11821 cccgtaggat taggaatttg ttggctgact tgattgtaga atgtgaattt actcagactg
    11881 acttggaaga cttggaagct gtgatttcag agaagaaatc aagtgctgta acagaagtaa
    11941 gatgtaattg tatgtaaagg agacgccatg ttaaatagta ttgtaaccat tatttgtatt
    12001 gcccttatcg cgtttatctt gttttggttt ttcaaaaagc ctgaaaaatc tggacaaaaa
    12061 gcccagcaaa aaaacggata ccaagagatt cgagtggaag tcatgggagg ctatactcct
    12121 gagttgattg tcctcaagaa atcagtgcca gcccgcattg tctttgaccg caaggatcct
    12181 tcaccatgtc tggatcaaat tgtttttcca gattttggtg tacatgcgaa cctgccaatg
    12241 ggggaagagt atgtagtgga aatcatgcct gaacaggctg gagagtttgg ctttgcttgt
    12301 ggtatgaaca tgatgcacgg caagatgatt gtagagtagg tggagactat gacagaaatt
    12361 gtgaaagcaa gcttagaaaa tggcattcaa aaaatccgta tccgagctga aaaaggctat
    12421 catccagccc atatccagct tcaaaaggga attccagctg agattacctt tcatcgtgct
    12481 actccttcaa actgttataa ggaaattctg tttgaagaag aaggtatctt ggaaccaatc
    12541 ggcgtagatg aggagaaagt cattcgtttt acgcctcaag aattagggcg acatgaattt
    12601 tcttgtggca tgaagatgca aaagggaagc tatacagtcg ttgagaagac tcgaaaatct
    12661 ctatctctcc tgcaacgttt ttggattact agtatcttta ctgtgcctct tgtgattctc
    12721 atgattggga tgttgacagg tagcattagt catcaagtca tgcattgggg aaccttttta
    12781 gcaacaacgc ctattatgtt agttgcaggt aagccatata tccagagtgc ttgggccagt
    12841 tttaaaaagc acaatgccaa catggatacc ttggttgcgc tgggaactct agtggcttat
    12901 ttctatagcc tagttgctct ctttgctggt ctccctgttt acttcgaaag tgctggattt
    12961 atcctctttt tcgttctttt gggagcagtt tttgaggaaa aaatgagaaa aaatacgtcc
    13021 caagctgtgg agaaattact ggacttgcaa gctaaaaccg cagaagtctt gagtgatgat
    13081 agttatgtcc aagttccttt ggaacaagtc aaggtaggcg acctgattcg agtgcgtccc
    13141 ggtgaaaaga ttgctgttga tggtgtcgta gtagaaggtg tctctagtat tgacgaatcc
    13201 atggtgacag gtgagagtct gcctgtggac aagacagttg gagatactgt cattggctca
    13261 accatcaatc atagtggaac gcttgtcttt agagcagaaa aagttggctc agagactgtt
    13321 ttggctcaga ttgtggattt tgtgaagaaa gctcagacaa gtcgtgcgcc gattcaggac
    13381 ttgacggata agatttcagg gatttttgtc ccagtagttg tcattttagg aatcatgacc
    13441 ttttgggttt ggttcgtctt gctcagggat agtgtggttg tgcttggagc tagctttgtg
    13501 tcctctcttc tctacggagt ggcggttttg attatcgcct gtccttgtgc cttgggactt
    13561 gcaacaccga cagcccttat ggtggggaca ggacgtagtg ccaagatggg ggttctcctc
    13621 aaaaatggaa ctgtcttaca ggaaatccag aaagttcaaa ctcttgtctt tgataagacc
    13681 gggactttga cggaagggaa acctgtggta acagatgtca tcggcgacga agtagaagtg
    13741 tttgggttgg cagcctcctt ggaagatgct tctcaacacc cactggctga ggctatcgtt
    13801 aagcgagcga gtgaagctgg acttgagttt caaactgttg aaaattttca gaccttgcac
    13861 gggaaaggtg tttcagggcg aatcaatgga aaacaagttt tacttggaaa tgctaaaatg
    13921 ctggatggca tggatatttc taatacttat caagataaac tagaagaact agaaaaagaa
    13981 gctaagacag ttgtgttctt agctgttgac aatgaaatca aaggcttgct tgctttgcaa
    14041 gatattccta aggaaaatgc taagctagtc atcagtcagc taaaaaaacg tggtctccga
    14101 acagtcatgc tgacaggaga caatgctggt gtggcgcgtg ctattgcaga tcaaatcgga
    14161 attgaagagg tcattgcagg cgtcttgcca gaagaaaaag cccatgaaat ccataaactg
    14221 caacagtcag ggaaagtagc ctttgttggg gacggtatca atgacgctcc tgcccttagt
    14281 gtagcagatg tggggattgc tatgggagct ggaacagata tcgccatcga atcagcagat
    14341 ttggtgttga caaccaataa tcttttagga gtggttcgtg cctttgatat gagtaagaaa
    14401 acctttcatc gaattctact caatcttttc tgggctttta tctacaatgt tgttggaatt
    14461 ccgattgcag caggagtctt ttcaggtgtt ggactggctc tcaacccaga attggcaggt
    14521 ctagccatgg cctttagttc tgtatctgtt ctgaccagtt cccttctgtt aaattttagt
    14581 aaaatagact aaaagtaatg actagatttc tttgttataa aacagaaatg acaacacttt
    14641 caaaactgta ttataataga gaatagagag ttttgagcag atttttagaa aagtcagcat
    14701 aaatatgata cagtggaata gtaaaaattt ggagaacgtt tccaattcta tgtaatcgta
    14761 ttctccaagt ctaaaaaaat tgaaggagag ttatcattat gactcaaggg aaaattactg
    14821 catctgcagc aatgcttaac gtattgaaaa catggggcgt agatacaatc tacggtatcc
    14881 catcaggaac actcagctca ttgatggatg ctttggctga agacaaagat atccgtttct
    14941 tacaagttcg ccacgaagag acaggtgctc ttgcagcggt tatgcaagct aaattcggcg
    15001 gctcaatcgg ggttgcagtt ggttcaggtg gtccaggtgc gactcacttg attaacggtg
    15061 tttacgatgc agctatggat aacactccat tcctagcgat ccttggatca cgtccagtta
    15121 acgaattgaa catggatgct ttccaagagc ttaaccaaaa cccaatgtac aacggtatcg
    15181 ctgtttacaa caaacgtgta gcttacgctg agcaattgcc aaaagtaatt gacgaagcct
    15241 gccgtgctgc agtttctaaa aaaggtccag ctgttgttga aattccagta aacttcggtt
    15301 tccaagaaat cgatgaaaac tcatactacg gttcaggttc atacgaacgc tcattcatcg
    15361 ctcctgcttt gaacgaagtt gaaatcgaca aagctgttga aatcttgaac aatgctgaac
    15421 gcccagttat ctatgctgga tttggtggtg ttaaagctgg tgaagtgatt actgaattgt
    15481 cacgtaaaat caaagcacca atcatcacaa ctggtaaaaa ctttgaagct ttcgaatgga
    15541 actatgaagg tttgacaggt tctgcttacc gtgttggttg gaaaccagcc aacgaagtgg
    15601 tctttgaagc agacacagtt cttttccttg gttcaaactt cccatttgct gaagtttacg
    15661 aagcattcaa gaacactgaa aaattcatcc aagtcgatat cgacccttac aaacttggta
    15721 aacgtcatgc ccttgacgct tcaatccttg gtgatgctgg tcaagcagct aaagctatcc
    15781 ttgacaaagt aaacccagtt gaatcaactc catggtggcg tgcaaacgtt aagaacaacc
    15841 aaaactggcg tgattacatg aacaaactcg aaggtaaaac tgagggtgaa ttgcaattgt
    15901 atcaagttta caatgcaatc aacaaacatg ctgatcaaga cgctatctac tcaatcgacg
    15961 taggtaacac tactcaaaca tctactcgtc accttcacat gacacctaag aacatgtggc
    16021 gtacatctcc actctttgcg acaatgggta ttgcccttcc tggtggtatc gctgctaaga
    16081 aagacaatcc agatcgccaa gtatggaaca tcatgggtga cggagcattc aacatgtgct
    16141 acccagacgt tatcacaaac gttcaatacg accttccagt tatcaacctt gtcttctcaa
    16201 atgctgagta cggcttcatc aagaacaaat acgaagatac aaacaaacac ttgtttggtg
    16261 tagacttcac aaacgctgac tacgctaaaa ttgcggaagc tcaaggagct gttggattca
    16321 cagttgaccg tatcgaagac atcgatgcag ttgttgcaga agctgttaaa ttgaacaaag
    16381 aaggtaaaac tgttgtcatc gatgctcgca tcactcaaca ccgtccactt ccagtagaag
    16441 tacttgaatt ggatccaaaa cttcactcag aagaagctat caaagccttc aaggaaaaat
    16501 acgaagcaga agaactcgta ccattccgtc tcttcttgga agaagaagga ttgcaatcac
    16561 gcgcaattaa ataattcctc tcgccgaaaa tcaaatatga aacttgtaga ctttattctt
    16621 tgattttcat agagcagaac tttaaaagat cggagcaatc cggtcttttt atggaggaga
    16681 gtaaatgaat ttaaatcaat tagatattat cgtttcaaat gttccccaag tctgtgctga
    16741 cttggagcat atcttggata aaaaggcaga ttatgctgat gatggttttg ctcagtttac
    16801 gattggtagt cactgcctta tgttgtcaca aaatcatttg gttcctttgg aaaactttca
    16861 gtcaggaatc attattcata tcgaggttga ggatgtagac cagaactaca aacggttgaa
    16921 cgagcttggt ataaaggttt tacacggacc aactgtaacc gattggggaa cagagtcctt
    16981 attagttcaa ggacctgctg gtctagtgct tgatttttat cgtatgaaat aggtcgcgta
    17041 gtcatttgac gttaacctta gctattttta aaatagaaat tgagaatatg aactattgaa
    17101 agatcggagc aatccggtct ttttatataa agaaattgca tataatactc atctgctttc
    17161 aaaaagcatt ctagtccatc tccgattaac gatggacttt atcacctcct tctccaatcc
    17221 ttgtatgaca tcttggagtt gattcatgac atcttccaaa gttcgaaagg ctttattctt
    17281 aaatccacgt ttacgaatct ctttccacac ttggtcaatg gggttcatct ctggtgtgta
    17341 tggaggaata aatgcaaagc caatattagt cggaatcttt aaggtacttg atttatgcca
    17401 tatagcattg tctataacga gtaaaaaata atcatatgga taagcttgtg aaagctcttc
    17461 taaaaaggcg ttcatccact cagtattaca tctaccagct attaagaaaa atgattcgcc
    17521 tgtatgggca tcaacagctc cataacaata gcgaaattct cgtatatagt gactatggac
    17581 atgtggacct actcctattg gagaccaaca agatcccagt ttactgattc taccgaaacc
    17641 agcttcatct tggtacatca agcgaacctt atgaaaaggt ctactggttt taaagcgctt
    17701 tcttgtcttc ttgaattgag attttatttt tagatgcgac aatggtttga gcgtctgctt
    17761 tcttaggatg ttctggacgt ggcgtaatat ttcgccaacc atggcgcttc aacagttgat
    17821 agaaggcatc acgtgtgtag gaacgaccta actccttttt ataagcctga aataaggcat
    17881 caattgtaac aaattctcct gcctctgtag ccttcaaatg gcgagcaaga aaggctttct
    17941 cttcctcaac tgtcatatat gcatggttac gaccaccacg tgtttcttga aggagagagt
    18001 cgagtccgaa ctcctcatat tttttacatt tcgccaaatc gttgtttgat tacagtctaa
    18061 aagctctata atctctttat aagatttgcc catcagacga aatagaacga tttgaaggcg
    18121 tttatgatat ttagctgtac gagagtcttt taaaagtgtt ttgatggttt ggatttcttc
    18181 tttagtcaat ttcatatcac tattatataa tgctttttga ttttagttta gtattatcgt
    18241 agaaaatgga ctcggtacta tggatacacc ggatgagaat ggttatgtag cagatgacta
    18301 tcggattact tacttagagg cccacatcaa ggccatgcga gatgccattt accaagacgg
    18361 ggttgacttg cttggttata cgacttgggg ctgtatcgat ccggtttcag ctggcacagg
    18421 ggaaatgaat aagcgctatg gctttatcta tgtagatcga gataatgtag gaaacggagt
    18481 tctcaaacgt agcaagaaga agtccttcta ttggtacaag gatgtcattg atagcaatgg
    18541 tgcaagcatc gagtagagca catttgttta ctatttttat aaaatcttct ccctgcttta
    18601 taagatgtaa aaaagagttc aaatggaact ctttttttgc tataatgagg ggagaaaaat
    18661 cagacaggag attaagatgt cagaaccatt atttttacaa tcagttatgc aagaaaaaat
    18721 ctggggtggt accaagctac gtgatgagtt tggctacgac atcccaagtg aaaaagtcgg
    18781 agaatactgg gctatctcag ctcatctaaa tggtgtttct aaagttgcca atggtcgtta
    18841 cgagggaaca gatcttgcta ctttgtatgc ggaacaccgt gaattatttg gcaatcgtcc
    18901 agaacctgta tttccacttt tgaccaagat cctcgatgcc aacgactggc tcagtgtcca
    18961 agttcaccca gacgatgctt atggactcga gcatgaaggc gaactcggaa aaacagaatg
    19021 ctggtacatc atcgctgcgg atgaaggttc agagattatc tacggtcaca atgccaagtc
    19081 aaaagaagaa ctccgccagc aaatcgagga caagaactgg gataccttgc ttaccaaagt
    19141 ccctgtcaag gctggagatt tcttctatgt accaagtggc accatgcatg ctatcggtac
    19201 tggcatcttg attcttgaaa cccaacagtc tagtgatacc acttaccgtg tctatgactt
    19261 tgaccgtaag gatgacaaag gcaacttgcg tgaacttcat cttgaaaaat ccatcgatgt
    19321 cttgaacatt ggtgagccag caaatagccg tcctgtaact gttaaagcag atgatttgcg
    19381 ttccactctc cttgtatcta atgatttctt cgcagtttac aagtgggaaa ttactggaaa
    19441 agttgacttt gaaaagacag ctgactacag cttattgagt gtcttagctg gtcaaggtca
    19501 gctaactgtt gacgggaaaa attatccaat tcaaaaaggg agacacttta tcctaccaag
    19561 tgatgttgaa gcttggactc tggaagggca aggtttggaa ttgattgtta gccatccata
    19621 aaaagaaagg gcctgagttc actactcaag tcctttttga ttacataaat tgggcaatga
    19681 agaccacaat gatgatgatt ggaatgacga aacgaagaaa cgaagaagga agagccagac
    19741 ttggaacagt ccttgtttcc atgctctttc atcgagatgg agttcctcca ttgcaagagc
    19801 ctttttaaag atatagcctg taaaaagtga aaggtagaga gctccaaatg gcatgaggag
    19861 attggaagcc aagaagtcca tagcgtcaaa gaagatctta ccaaaaatgt gaacatccgc
    19921 catgacaccg taagataggg ctgaaggaat gccaaagaca aaggtcaaaa ttcctaaaat
    19981 aacactccat ttggcacgtt tgctgttatc ctggttggtg atattgccca cattgatctc
    20041 cagcatcacg acagaagaag tgacagtcgc aaagaggaag aggacgtaga aaatggttcc
    20101 aaaaggcatc ttgtcaaaga gttgaggtaa gacgataaag agcaggggca tcatgactgt
    20161 aacccctagt gagagggcaa agaaagattg tcccagagca tagaggagac cagcgctagt
    20221 cagttttgaa aagtctggtt tgaggaagta aagaacccct tccatggcat ttggcaaact
    20281 gagagagcga ccgatgataa caacaaagat gataaagagc aggggcatca tgactttcga
    20341 agctctttca atcccttttt gaaccccacg tgatacaata aagatattta ataagataaa
    20401 ggctgcttga gctactaggg caatggctgg atttgaaatg attgaagtaa ataactgagc
    20461 ataatcaccc gttccaccaa gttggaacaa tttcccaaac tcaataccta gatagactag
    20521 aatccatcct ccgataacac tgtaaaaaga taagaggata aagagggcaa aggcgccaat
    20581 ccaaccgata aagttgtact tgttattctt gcccagtttt ccaaaggttt tgatagcgga
    20641 aacgccagca ctacggccaa gggcaaactc agccagcagg agagggaaac cgattaaaat
    20701 agtggaaatg agaaagatta gtaaaaagcc tccaccgcca ttagcagcag tcatgtaggg
    20761 aaacttccaa acggaaccaa gcccgatgac cgagccagca gatgctagaa taaagccaag
    20821 tttcgacccc cattgtgatt tttctgacat agttaaactc tgatctcctt tttcaaaata
    20881 agaaaaagct acttgagttg tcaaatagcc ttctgtttga ttgatagact tgactatcct
    20941 attatgtttt ctaaggtctg tcaagaaaac cattttcaag ttttcacacc tttctcaaaa
    21001 acgcttaact ctgacctaag gggaggggtt atactatcat tgtaaggagg aaatcatgta
    21061 ccatataaaa gaagctgcgc agctttcagg tgtctctgtc aagaccctgc cctgcatcac
    21121 tatgacaaga taggactctt ggtcccctta aagtcggaaa acggctatcg aacctatagt
    21181 caagaggatt tggaacgcct tcaggtcatt ctttactaca aatatctagg cttttcttta
    21241 gagaaaatag cagagctgtt aaaggaagaa aggacagatt tattgcccca tttaactagg
    21301 cagttggact atctaactcg cgaaaggcaa catctggata ccttgatttc caccttgcaa
    21361 aaaactattc aagaacaaaa aggagaaaga aaaatgacca ttgaggaaaa attcacggga
    21421 tttagctatc aagacaatca aaaataccac caagaagcgg tagagaaata tggtcaagaa
    21481 gtcatgggac aagcgcttga acgccaaaaa ggtcacgaaa acgaggctac ggccgccttt
    21541 aaccaagtct ttcaaacttt ggcacaaaat cttcaagctg gtttacctgc aacagcaacc
    21601 gaaaaccaag agcaagcagc caagctcttg caagccattc gcacttatgg atttgactgc
    21661 tctattgagg tattcggtca tatcggtaaa ggttacgtct acaacccaga gtttaaggaa
    21721 aacattgaca agtttggttc tggaacagcc cagtacacgt cagatgccat tgcggcttac
    21781 gttcagacaa atgcagaaaa aataggctag gaatttccta gcctattttt tacttcaaat
    21841 cataaagcca gtcgtcaccg tttttgtagt aaaagaattc actgagatct tcttctagaa
    21901 acacacgaag catatcagac atatcatcgg ttgcaagttt tagatgagaa agattttcaa
    21961 agtcctccca ctaaactttc ccttcgtctg aagactggag ttcaccagta aagtgttctg
    22021 tcttgtaaaa aaggacgaca taacgataat ccttgtcgtc ataccagttt ttgataccac
    22081 agagttgggg tttggaaatg atcagaccag tttcttcttt cacttcacga atgacagcat
    22141 cgacaaagga ttcgccacgt tcaacatgac caccaggaaa agtaatgcca gaccagtcgg
    22201 gactaactcg gtcttggacc aggaccttat ctccgttttt aatcatacac atgttaacaa
    22261 attcgactgc ctctcttctg ttcattcttc acaaccttta atctttaatc ataatgcaga
    22321 cttcccgcca cccagccggt acagagggca gaagtgatgt taaagccacc cgtgtgggca
    22381 ttgatatcca taacttcgcc tgcaaagtgg aggccaggta ccagcttact ttcaagggtt
    22441 ttaggattga tttccttgag actgactcca cccttggtaa caaaggactt tgcaagggac
    22501 atttttccag ttacaggaat tttaagttct ttaatggact ggacaagttg ttctcgttcc
    22561 ttttcagtca gctgtttgac tttttcagga tatccttgta caaaaaattc ggccaagcgt
    22621 tctggtaaca aggtttttaa agcgtttttc aaggattttt cccgattttc ttctagaaat
    22681 gtaaccaagt ccttctcaga aagttgaggc aaaacatcga gtgagagaac ctccccacct
    22741 ttgacaaagc tagacatgcg tagggcagca ggacctgaca aaccaaagtg ggtaaagagt
    22801 aaatcatgag tgatgacatg cttaccataa cttagggtca catcgtccaa agaaatccct
    22861 tgtaaggctt tatgtggaaa atctgttaat aaaggacttt cagcagcctc aagctcggtg
    22921 atggtatgct taaaatggcg agcaatctcg tgaccaaaac cagtcgaacc agtcgaagga
    22981 taagacttac cacctgttgt gacaatgagt ttctcacaag tgaaggtttg atccgctgac
    23041 ttaaggacaa actggtcatc tactttttta acagaaacga tttctatttg agtagcaact
    23101 tgaccaccta gttcagtgat tttcttttcc aaagcttcga taatagtccg agacttgtca
    23161 ctggctggaa agacgcgtcc gtggtcttcg accttaagtt taacaccatt ttctgtaaaa
    23221 aagttgatga tgtcatgatt atcgaactgg gagaaaacac tgtaaagaaa gcgtccgttt
    23281 ccaggaattc cagctagcag gttgtctaag ctaccattgt tggtcacatt gcaacgtccc
    23341 ccaccagtcc cagctaattt ttttccaagt ttccgatttt tttcgatgag gagggttttc
    23401 tgtccataaa agctactgga aatcgtagcc atcataccag caggtccccc accgatgaca
    23461 atagtatcaa aatgtttcat agctctattg taccacaaaa aaacaagaga tgatggtcac
    23521 ctcttgtcaa gaatgcaatt aatcaatttc atagcccatc agcaaaccgc cctcttctgc
    23581 atagaaactg cagagaccag aggttggtag aattttaata tccgcttgtg ggaaggtttc
    23641 acggattcgc tctgagagct gttgacaaca tttttcgtta ttgcgttggg ccatgacaat
    23701 acggccacca gcatatccag cttttactaa ctcatcatag gcagcttgaa ctgatttctt
    23761 tgatcccctt gctttttgta gcaattcgag agttccagtt tcactagctt ttccgaccat
    23821 acgaatgttg agaaggccaa cgaccgtacc gataagcttg ctcaaacggc cgttcttcac
    23881 caagttatcg actttggcta ggacaaagag caacttagtt ttttcttgat aggcggtgat
    23941 agcttcaacc acttcttcaa aagacaagcc ctggtcaatc aagtcattca atttttctac
    24001 gagtaggtca acttcaccac cagcagataa actatcaatc acatgaatct tagtgtcagg
    24061 atggtcttcc agataaatat tctttgctag ttgagcacta ttgtgactgc cagaaagggt
    24121 acctgtgatg gttactagga aaatgttttt ggcaccttca aatgctcgca aatagtcatc
    24181 tgggcttgga caagccgatt ttgaagcttc tgcagttgca tacatggttt ccatcatttg
    24241 gtcaatatcg agactggcgt catcaacaaa gacctgatca gctacttgaa tggttaaggg
    24301 gacacttaca aaggttgtgt taatagctgg tgttggcagt tgacgataat cacaaccaga
    24361 gtcagcaata atcttccaag tcatagaaat tctccatctt tgtcagttat acattgacaa
    24421 aggttctgtc tttttttaca attatatcat gaaaaccctt gaaacaaaag catcatccgt
    24481 ctgttgtgac aagtagaaag aaaatgttat gtctgaacgt agaatctctg aaaagtctct
    24541 tgaaaatctc agaaaatcaa accaagaatc caatttatta accagagaag ccattgaaac
    24601 agccctcttg caactcttgg aaaaaaagga actgaccaag attagtattt ctgaattggt
    24661 caaacgtgca ggtgtttcgc gtgcggcctt ttatcgcaat tatgactcca aagaggaaat
    24721 tttagagagc gtctttaaac gaactgtcca caatattatg gaacagctgc atcattacga
    24781 tttaaagaca gacctttatt tggtttgggt tcaccttttc cgggaggcca gaaaggaagc
    24841 tagagtgatt caattggcct tggattacca tctggaaaaa atctttgtcc aagccatgca
    24901 ggaatttcta gaaaaatacc atgggaaatc aaaaggtgtc agctcttatc ttcattcctt
    24961 ctggagctca gccatcgtct ctgtccttct aaaatggatc aaggatggca tgaaggtacc
    25021 agctgaaaag attgcagatt taggtttacc attttttaaa aaatagagaa aaaggagaaa
    25081 agagatgact gaaaaaagac tggcctggga tgagtatttt gcagcccaag ccctactaat
    25141 tgcgaatcgt tccacttgta aacgtgctaa agtgggcgcg attctggtaa aagataataa
    25201 ggttatttcc actggttaca atggttcggt gtcagggact gagcattgta ttgatcacga
    25261 atgtttggtc attgaaggcc actgtgttcg cacccttcac gctgaggtca atgctatcct
    25321 tcaaggtgct gagcgtggtg ttcccaaagg ctttacagcc tatgtaaccc attttccttg
    25381 tctcaactgt acaaaacaat tgcttcaggt cggctgcaag cgtgtggttt atatcaacca
    25441 gtaccgaatg gacgactacg cccaatacct ttatcaagaa aaagggacag aattgaccca
    25501 tttaccactt gagacagtac agacagctct taaagaggct gatctaatgt aaaaattatc
    25561 aaaaataaat ggtttagaaa gatttttaaa ccgttttttg gtataataag aagaataaat
    25621 tgaaagaagg aattccaaaa atgggaaaaa ttgaagttat taatcaccca ctgattcaac
    25681 acaaattgtc aatcttgcgt cgtacagata cttctacaaa agcttttcgt gagctagtag
    25741 atgagattgc aatgttgatg gggtatgaag tacttcgtga tcttccacta gaagatgtgg
    25801 aaatcgaaac accaattaca aaaacagttc aaaaacaatt ggcaggtaag aaattggcca
    25861 tcgtcccaat cttgcgtgca ggtatcggga tggttgatgg tctcttgagc ttggttccag
    25921 ctgctaaagt tggccacatc ggtatgtacc gtgatgaaga aacacttcaa ccagttgaat
    25981 acttggtgaa attgcctgag gacattgacc aacgtcaaat ttttgtagta gacccaatgt
    26041 tggcaacagg tggctcagca atcttggctg ttgattctct taaaaaacgt ggcgcatcaa
    26101 atatcaaatt tgtctgcctt gtatctgctc cagagggtgt aaaagccctt caagaagctc
    26161 atccagatgt agaaatcttt acagcagcct tggatgaacg tttgaacgaa cacggttata
    26221 tcgttccagg tcttggagat gctggagacc gcttgttcgg tacaaaataa gatcgaaaag
    26281 aagaatgact tggaaaagta tttccagtca cgaaaggagg ttgggttttt gtttctgtct
    26341 aatgaaagca gagcaaaaat ttgacctttt ttgaccaaga tattataata gtcttatctt
    26401 cagtcatttg accaacaaaa ttaaaactca aaaggagaaa tgaatgattc ctgtagttat
    26461 tgaacaaaca agccgtggag aacgttctta cgatatttac tcacgtcttc tcaaagaccg
    26521 catcattatg ctgacaggtc cggttgaaga caatatggct aactctgtta ttgcccaatt
    26581 gcttttcttg gatgcccaag atagtacaaa agatatttac ctttatgtca atacaccagg
    26641 tggttctgtt tcagctggtt tggcaatcgt agataccatg aactttatca aggcagatgt
    26701 ccaaaccatt gttatgggaa tggctgcatc tatggggact gtcatcgcat caagtggggc
    26761 aaaaggcaaa cgtttcatgc ttccaaatgc tgaatacatg attcaccaac caatgggcgg
    26821 tacaggtggt ggtacccaac aaactgatat ggctatcgct gcagaacact tgctcaaaac
    26881 tcgtaatacc ttggaaaaaa tcttggctga aaattcaggt cagtcaatgg aaaaagtcca
    26941 tgcagatgca gaacgtgata actggatgag cgcccaggaa acacttgaat atggctttat
    27001 tgatgaaatt atggccaaca attcattgaa ctaatgatga tagaaggcaa actcgactgg
    27061 gtttgctttt tttggtataa tagggagaga tttcttagaa agaggattta tcatgtttga
    27121 aaaagtcaat cgctctggct tgattatcta tctttactat aatcgtgatg ccaaaaaact
    27181 gcaggattat ggagatatta cctatcattc caagaaacat cgttacttac aactctatgt
    27241 tccaactcaa gaagtggagc aattggtcgg acgcttgagc aaggaaaaat ttattaaaaa
    27301 agttagggtt tgtcatatcc aagagttgga aacacccttt gtgggcaatc tttatcgata
    27361 ggaaaacgtt atcatcgaaa aaagctcaag gaaaacattg acaattttct gataattcgg
    27421 tatattctta acagactatt taagaaataa ggagacaaaa agatgaagaa aaaatttgcc
    27481 ctatcgtttg tggcgcttgc aagtgtagca cttcttgcag cctgtggaga agtgaagtct
    27541 ggagcagtca acactgctgg taactcagta gaggaaaaga caattaaaat cgggtttaac
    27601 tttgaagaat caggttcttt agctgcatac ggaacagctg aacaaaaagg tgcccaattg
    27661 gctgttgatg aaatcaatgc cgcaggtggt atcgatggaa aacaaatcga agtagtcgat
    27721 aaagataata agtctgaaac agctgaggct gcttcagtta caactaacct tgtaacccaa
    27781 tctaaagtat cagcagtcgt aggacctgcg acatctggtg cgactgcagc tgcggtagcg
    27841 aacgctacaa aagcaggtgt tccattgatc tcaccaagtg cgactcaaga tggattgact
    27901 aaaggtcaag attacctctt tattggaact ttccaagata gcttccaagg aaaaattatc
    27961 tcaaactatg tttctgaaaa attaaatgct aagaaagttg ttctttacac tgacaatgcc
    28021 agtgactatg ctaaagggat tgccaaatct ttccgcgagt catacaaggg tgaaatcgtt
    28081 gcagatgaaa ctttcgtagc aggtgacaca gacttccaag cagcccttac aaaaatgaaa
    28141 gggaaagact ttgatgctat cgttgttcct ggttactata atgaggctgg taagattgta
    28201 aaccaagcgc gtggcatggg aattgacaaa ccaatcgttg gtggtgatgg attcaacggt
    28261 gaggagtttg tacaacaagc aactgctgaa aaagcatcaa acatctactt tatctcaggc
    28321 ttctcaacta ctgtagaagt ttcagctaaa gctaaagcct tccttgacgc ttaccgtgct
    28381 aagtacaatg aagagccttc aacatttgca gccttggctt atgattcagt tcaccttgta
    28441 gcaaacgcag caaaaggtgc taaaaattca ggtgaaatca aggataacct tgctaaaaca
    28501 aaagattttg aaggtgtaac tggtcaaaca agcttcgatg cagaccacaa cacagtcaaa
    28561 actgcttaca tgatgaccat gaacaatggt aaagttgaag cagcagaagt tgtaaaacca
    28621 taatagaaaa atgttgaaat agggaatgag cctttgactc actccctgtt tcgatattta
    28681 atactcttcg aaaatctctt caaactgcgt caacgtcgcc ttggattata tatgtgactg
    28741 acttcgtcag tcttatctac aacctcaaag cagtgctttg agcaacctgc ggctagtttc
    28801 ctagtttgct ctttgatttt cattgagtat aagaacctat caaaaagtga gggaaacccc
    28861 tcggaattat aaatagaaag agtgaatctt atgctccaac aactcgtaaa tggtttgatt
    28921 ctaggtagtg tttacgcgct gttagcccta ggatatacca tggtttacgg aattatcaag
    28981 ctcatcaact tcgcccatgg tgatatttat atgatgggag cctttatcgg ttatttcttg
    29041 atcaattctt tccaaatgaa tttctttgta gcgcttattg tagctatgct agcgacagct
    29101 attcttggtg tcgtgattga gtttcttgct taccgacctt tgcgccactc tactcgtatt
    29161 gctgttttga ttacggctat tggggtttct ttcctattgg agtatggaat ggtctatctg
    29221 gttggtgcca atacccgtgc cttccctcaa gcgattcaaa cagttcgata tgatttggga
    29281 ccaattagct taacaaatgt gcagttaatg attttgggca tttccttgat tttgatgatt
    29341 ttgttacaag tcattgtcca aaagactaag atggggaaag ccatgcgtgc agtatcagta
    29401 gatagcgacg cggcgcaatt gatggggatc aatgtaaacc gtacgattag ctttaccttc
    29461 gctttgggtt ctgctcttgc gggtgcggct ggtgttctga ttgctcttta ttataactct
    29521 cttgagcctt tgatgggggt tactccaggt cttaaatctt tcgttgccgc agtacttggt
    29581 ggtatcggaa ttattcctgg tgctgctctt ggtggctttg tgattggtct attggaaacc
    29641 tttgcgacag cctttgggat gtcagatttc cgtgatgcca ttgtttatgg aatcttgttg
    29701 ttgatcttga ttgtccgccc agctggtatc cttggtaaga atgtgaaaga gaaggtgtaa
    29761 acgatgaagg aaaatttaaa agttaatatt ctatggttac tccttttgtt agctggctat
    29821 agcttgatta gtgtactggt ttcagtcgga gtacttaatc tattctatgt acagatttta
    29881 caacaaattg gaattaatat tattttggct gttggtctca acttaatcgt tggtttttca
    29941 ggacaatttt cacttggtca tgctggtttc atggcgattg gtgcctatgc agcagctatt
    30001 attggttcta aatcaccaac ctacggtgcc ttctttggag ctatgcttgt aggggctttg
    30061 ctttcaggag cagttgcctt acttgtcggc attccaacct tgcgcttgaa gggggactat
    30121 cttgcggtag caactctagg tgtttctgaa attatccgta tctttatcat caatggtgga
    30181 agccttacaa atggtgcggc aggtatctta gggattccta actttacaac ttggcaaatg
    30241 gtttacttct ttgtcgtgat tacaaccatt gcaaccttga acttcttgcg tagcccaatt
    30301 ggtcgttcaa ccctctctgt tcgtgaagat gaaatcgctg ctgagtcagt tggggttaat
    30361 acgactaaaa ttaaaatcat cgcttttgtc tttggtgcca ttactgcaag tattgctggg
    30421 tcacttcagg caggatttat cgggtctgtt gtaccgaaag attacacctt catcaactca
    30481 atcaacgttt tgattattgt tgtatttggt ggactcggtt ccattacagg tgcgattgtt
    30541 tcggctattg ttctgggaat tttgaatatg cttctccaag atgttgctag tgtgcgtatg
    30601 attatttacg ctttggcctt ggtattggta atgattttca gaccaggtgg actccttgga
    30661 acgtgggaac tgagcctatc acgtttcttt aaaaaatcta agaaggagga acaaaactaa
    30721 tggcattact tgaagtaaaa cagttaacca aacattttgg tggtctaaca gctgttggag
    30781 atgtgactct tgaattgaac gaaggggaac tggttggatt aatcggtcca aacggagctg
    30841 ggaaaaccac ccttttcaac cttttgaccg gtgtttatga accaagcgag ggaacagtaa
    30901 ccctagatgg tcaccttttg aatgggaaat caccttataa gattgcctct ttgggacttg
    30961 gacgtacttt ccaaaatatc cgtcttttta aagatttaac agttttagac aatgttttga
    31021 ttgcttttgg aaaccatcac aaacagcatg tttttactag tttcttacgc ttaccagctt
    31081 tttacaagag tgaaaaagaa ttaaaggcta aagctttgga attgttgaaa atctttgatt
    31141 tagatggtga tgcagagact cttgctaaaa atctttccta cggacaacaa cgtcgtttgg
    31201 aaattgttcg tgcccttgct acggaaccta aaattctctt cttagatgaa ccagcagcag
    31261 gtatgaaccc acaggaaaca gccgaattga ctgagttaat tcgtcgtatc aaagatgaat
    31321 ttaagattac aatcatgttg attgaacacg atatgaatct ggtcatggaa gtaacagaac
    31381 gtatctacgt acttgaatat ggccgtttaa ttgctcaagg aactccagac gaaattaaga
    31441 ccaataaacg cgttatcgaa gcttatctag gaggtgaagc ctaatgtcta tgttaaaagt
    31501 tgaaaatctt tctgtgcatt acggtatgat ccaagcagtc cgtgatgtaa gctttgaagt
    31561 taatgaagga gaagttgttt cccttatcgg tgccaacggt gcaggtaaga caactattct
    31621 tcgcaccttg tcaggtttgg ttcgaccaag ttcaggaaag attgaatttt taggtcaaga
    31681 aatccaaaaa atgccagctc agaaaattgt ggcaggtggt ctttcacaag ttccagaagg
    31741 acgccacgtc tttcctggct tgactgttat ggaaaatctt gaaatgggag ctttcttaaa
    31801 gaaaaatcgt gaagaaaatc aagctaactt gaagaaggtt ttctcacgct ttcctcgtct
    31861 tgaagaacgt aagaaccaag atgcagctac tctttcagga ggggaacaac aaatgcttgc
    31921 catgggacgc gctcttatgt caacaccaaa acttcttctt ttagatgaac catcaatggg
    31981 acttgcccca atcttcatcc aagagatttt tgatatcatt caagatattc agaagcaagg
    32041 aacaaccgtc ctcttgattg aacaaaatgc caataaagca cttgcaatct ctaaccgagg
    32101 atatgtactg gaaacaggga aaatcgtcct atcaggaaca ggaaaagaac tcgcctcatc
    32161 agaagaagtc agaaaagcat atctaggtgg ctaaaacaat ccagtggatt gttttagtcg
    32221 gcagatgaag attacgaagt aatcatcatt atagtctggg agactagttt aggttgcaga
    32281 taaagattgc gaagcaatca tcaaatccag aggattgttt tagccggcag atggagatta
    32341 cgaagtaatc atcaatatag tccgggggac ctttttagtc ggtggataga gattgcaaac
    32401 aaatatgcat ctacattgaa agcttaattt ctaataattg aaaaaatcga atgaaaaatt
    32461 tcttaccttc attcacagag ctctatttca gagctctttt tgctagctta ttcatacttt
    32521 tttgaatttc gaaaaagaaa tgtaagcgtt tgatagattt acaaaaagat tgtataatgg
    32581 ggataagaat agaaaaggag aagtctcatg gcagttaaag attttatgac ccgcaaggta
    32641 gtttatatta gtccagatac aacagtatct catgcagcag atttgatgag agagcaaggt
    32701 ttgcaccgtc tgcctgttat cgaaaatgat caattagttg gtttggtgac tgagggaacc
    32761 attgcacaag caagtccatc taaagcaaca agtctttcta tctatgagat gaattatctt
    32821 ctgaataaga caaaagtaaa agatgtcatg attcgcgatg ttgtcactgt ctcaggctat
    32881 gctagtctag aagatgcaac ttatctgatg ttgaaaaata agattggtat tctccctgtc
    32941 gtagataact atcaagtata cggagttatt actgaccgtg atgttttcca agcctttctt
    33001 gaaattgcag gttatggcga agaagggatt cgtgtacgct ttgttacaga agatgaagtt
    33061 ggtgttcttg gaaaaattgt ttctttgatt gtagaagaaa atttgaatat ctcccataca
    33121 gtcaatattc cgcgtaagga tggtaaggtg attatcgaag tgcaaatcga tgaatcaatt
    33181 gatttaccag ccttgaaaga aaaatttgaa gcaaatggta ttcaagtgga agaaatcgct
    33241 cgcacttcag caaaagtctt gtaagaaggg aagtccaaag gcttcttttt tcatgaaaag
    33301 gggattagag caaaagatgg aaagaaatga taaaatatgc tataatgaaa taatgtaaaa
    33361 aaggagtatt tatggacatt tcagtaattc gtcagaaaat tgacgcaaat cgtgaaaaat
    33421 tagcttcttt cagggggtct ctttgacctc gaagggctag aggaagagat tgccatcttg
    33481 gaaaacaaga tgacagaacc tgatttttgg aacgataata ttgcggccca aaaaacgtcg
    33541 caagaattga atgaattaaa aaacacttac aataccttcc ataagatgga agagttgcag
    33601 gatgaagtcg aaattttatt ggattttttg gctgaagacg agtcagtgca tgatgaactg
    33661 gtagcgcagt tagccgaact tgataagata atgaccagct acgagatgac tctactcttg
    33721 tcagaacctt atgaccacaa caatgccatc ttggaaatcc atccaggttc tggtggtact
    33781 gaggcgcagg actggggtga tatgttgctt cgtatgtata ctcgttatgg taatgctaaa
    33841 ggctttaaag tggaagtgtt ggattaccaa gcaggtgatg aggctggtat taagtcggta
    33901 actttatcat ttgaagggcc taatgcctat ggtctcctca agtcagaaat gggtgttcac
    33961 cgcttagtgc gaatctcacc atttgactct gccaaacgtc gccatacctc tttcacatct
    34021 gtagaagtga tgccagaatt ggatgatact attgaagtgg aaatccgtga agatgatatc
    34081 aagatggata ccttccgttc aggtggtgcc ggtggacaaa acgtcaataa ggtttcaaca
    34141 ggtgtacgtt taacccacat tccaactgga attgttgtcc aatcaacagt ggatcgtacc
    34201 cagtatggaa atagagatcg tgccatgaag atgttgcagg ctaagctcta tcaaatggag
    34261 caagataaga aggctgcgga ggtagattct ctcaaaggtg agaaaaagga gatcacttgg
    34321 ggaagccaaa tccgttctta tgtcttcacg ccttatacta tggtaaaaga tcaccgaact
    34381 agctttgagg ttgctcaggt agataaggtt atggatgggg acctagatgg ttttatcgat
    34441 gcttatctca agtggcgaat tagctaagat agaaaggaac tcacatgtca attattgaaa
    34501 tgagagatgt cgttaaaaaa tacgacaacg gaacgactgc tctacgcggt gtttcggtca
    34561 gcgttcaacc gggggaattt gcttacatcg taggaccttc aggagcaggg aagtcaactt
    34621 ttattcgttc tctgtatcgt gaagtaaaaa tcgataaagg aagtctatca gttgctggtt
    34681 ttaatctggt taagatcaaa aagaaagatg tcccgcttct acgtcgtagt gttggggttg
    34741 tcttccaaga ttataaattg ttaccaaaga aaactgtcta tgaaaatatt gcttacgcta
    34801 tggaagtaat cggggaaaat cgccgtaata tcaaaagacg agtgatggaa gttttggact
    34861 tggttggatt gaagcataag gttcgttctt tcccaaatga actctcaggt ggggagcaac
    34921 agcgaattgc gattgcgcgt gcaattgtaa ataatcccaa agtattgata gctgatgagc
    34981 caacaggaaa tctggatccg gataattcat gggaaattat gaatctcttg gaacggatta
    35041 acctacaagg gacaactatt ttgatggcga ctcataatag ccagattgta aataccttgc
    35101 gccaccgtgt cattgccatt gaaaatggcc gtgtcgttcg tgacgaatca aaaggagagt
    35161 atggatacga tgattagtag attttttcgc catttatttg aagccttaaa aagtttgaaa
    35221 cgaaatggtt ggatgacagt agctgctgtc agttcagtca tgattacttt gaccttggtg
    35281 gcaatatttg catctgttat tttcaataca gcgaaactag ctacagatat tgaaaataat
    35341 gtccgtgtag tagtttatat ccgaaaggat gtggaagata atagtcagac aattgaaaaa
    35401 gaaggtcaaa ctgttacaaa taatgactac cacaaggtat atgattcttt gaagaacatg
    35461 tctacggtta aaagtgttac cttttcaagt aaagaagaac aatatgaaaa attaaccgag
    35521 ataatgggag ataactggaa aatctttgaa ggagatgcca atcctctcta tgatgcctat
    35581 attgtagagg caaacactcc aaatgatgta aaaactatag ccgaagatgc taaaaaaatt
    35641 gaaggtgtct ctgaggttca agatggcggt gccaatacag aaagactttt caagttagct
    35701 tcatttatcc gtgtttgggg actagggatt gctgctttgt taatttttat cgcagttttc
    35761 ttgatttcaa ataccattcg tattaccatt atttcccgca gtcgcgaaat tcaaatcatg
    35821 cgcttggtcg gagctaaaaa cagttatatc cgtggaccgt tcttgttaga aggagccttt
    35881 atcggtttat tgggagctat cgcaccatct gttttggtct ttattgttta tcaaattgtt
    35941 taccaatctg tcaacaaatc gttggtaggg caaaatctat ccatgattag tccagattta
    36001 tttagtccgt tgatgattgc cctactattt gtgattgggg ttttcattgg ttcattggga
    36061 tcaggaatat ccatgcgccg attcttgagg atttaggtaa aatagctgct tttatgagga
    36121 gattgtaaaa tctccttttt tgctacaaga gtttttgaaa agagatgcgt agaagaaaag
    36181 agcttccaaa gaagtccccc agagaagact tcttgatggc taatttgaac ttgaaatttg
    36241 gcgcactaga aattttttag aaaaaagtgt aattttttta taaaagcctt tacaaaaaaa
    36301 attaaagtgg tataattaaa tcatagaagg tgcaaacgtt ttcgtaaaac gtttgcctaa
    36361 ataaaaataa aggagatttg aatgatgaaa gatacattca aaaatgtctt gtctttcgaa
    36421 ttttggcaaa aattcggtaa ggctttgatg gtagttatcg cggttatgcc ggctgctggt
    36481 ttgatgattt caatcggtaa gtctatcgtg atgattaacc caacctttac accacttgtc
    36541 atcacaggtg gaattcttga gcaaatcggt tggggggtta tcggtaacct tcatatcttg
    36601 ttcgccctcg ctattggagg aagctgggct aaagaacgcg ctggtggtgc tttcgccgct
    36661 ggtcttgcct tcatcttgat taaccgtatc actggtacaa tctttggtgt atcaggcgat
    36721 atgttgaaaa atccagatgc tatggtaact actctcttcg gtggatcaat caaagttgct
    36781 gattacttca ttagtgttat ggaagctcca gccttgaaca tgggtgtgtt cgtagggatt
    36841 atttctggtt ttattggagc aactgcttac aataaatact ataacttccg taagcttcct
    36901 gatgcacttt cattctttaa cggaaaacgt tttgtaccgt ttgtagttat tcttcgttca
    36961 ataattgctg caattgtact tgctgctttc tggccagtag ttcaaacagg tatcaatagc
    37021 tttggtatct ggattgccaa ctcacaagaa actgctccaa tccttgcacc attcttgtat
    37081 ggtacattgg aacgtttgct cttgccattt ggtcttcacc acatgttgac tatcccaatg
    37141 aactacacag ctcttggtgg tacttatgag gtcttaactg gtgcagcaaa aggtagccaa
    37201 gtatttggtc aagatccact ttggcttgca tgggtaacag accttgtaaa ccttaaaggt
    37261 actgatgcta gtcaatacca acacttgtta gatactgttc acccagctcg tttcaaagtt
    37321 ggacaaatga ttggttcatt cggtatcttg atgggtgtgg ttgtggctat ctaccgtaat
    37381 gttgatgctg acaagaaaca taaatacaaa ggtatgatga ttgcgacagc tcttgcaaca
    37441 ttcttgacag gggttactga accaatcgaa tacatgttca tgttcgtcgc aacacctatg
    37501 tatcttgttt actcacttgt tcaaggtgct gccttcgcta tggctgacgt cgtaaaccta
    37561 cgtatgcact cattcggttc aatcgagttc ttgactcgta cacctattgc aatcagtgct
    37621 ggtatcggta tggatatcgt taacttcgtt tgggtaactg ttctctttgc tgtaatcatg
    37681 tactttattg caaacttcat gattcaaaaa ttcaactacg caactccagg gcgtaacgga
    37741 aactacgaaa ctgctgaagg ttcagaagaa tctagcaacg aagtgaaagt tgcagcaggc
    37801 tctcaagctg taaacattat taaccttctt ggtggacgtg caaacatcgt tgatgttgat
    37861 gcatgtatga ctcgtcttcg tgtaactgtt aaagatgcag ataaagtagg aaatgcagag
    37921 caatggaaag cagaaggagc tatgggtctt gtcatgaaag gacaaggggt tcaagctatc
    37981 tacggaccaa aagctgacgt attgaaatct gatatccaag atatccttga ttcaggtgaa
    38041 attattcctg aaactcttcc aagccaaatg actgaagcac aacaaaacac tgttcacttc
    38101 aaaggtctta ctgaggaagt ttattcagta gcagacggtc aagttgttgc tttggaacaa
    38161 gtaaaagatc cagtatttgc tcaaaaaatg atgggtgatg gatttgctgt agaacctgca
    38221 aatggaaaca ttgtatctcc agtttcaggt actgtatcaa gcatcttccc aacaaaacat
    38281 gctcttggta ttgtgactga agcaggtctt gaagtattgg ttcacattgg tttggacaca
    38341 gtaagtcttg aaggtaaacc atttacagtt catgttgctg aaggacaaaa agttgtagca
    38401 ggtgatctcc ttgtcacagc tgacttggat gctatccgtg cagcaggacg tgaaacttca
    38461 acagtagttg tcttcacaaa tggtgatgca attaaatcag ttaaattaga aaaaacaggt
    38521 tctcttgcag ctaaaacagc agttgctaaa gtagaattgt aatatacttg aggttggaag
    38581 ctgtattcca acctcttatt ttgggagaaa agaatgaaat ttttaacact caatactcac
    38641 agttggatgg agaaagaagc agaggaaaaa ttccagattt tgcttgagga tattcttgaa
    38701 aaggactatg atttgatttg tttccaagaa atcaatcagg agatcacttc gccagaggtg
    38761 gaggttaatg acctttatca agctttgcca gcagctgagc ttattcacca agatcactat
    38821 gttagactct tggttgaaaa gttgttagag caagggaaaa attactactg gacctgggct
    38881 tataaccata tcggctatga ccgctaccac gaaggtgtgg ctatcttgtc taaaacacct
    38941 attgaagcca gagaaatttt ggtttcagat gtggatgatc caacagacta tcatactcgc
    39001 cgtgttgccc tagctgaaac tgtagtcgat ggcaaggagc tagcagttgc cagtgttcat
    39061 ctctcttggt gggataaagg tttccaagaa gaatgggcac gatttgaggc tgtcttgaaa
    39121 aaattgaaca agccactttt actagctgga gattttaaca acccagcagg tcaggaaggt
    39181 taccaagcta ttttagctag tccattaggc ttacaagacg catttgaagt tgctcaagag
    39241 aaaagtggta gctatactgt tccgcctgaa attgatggct ggaaagggaa cactgaaccc
    39301 cttcgaatcg attatgtctt tactaccaaa gagttagcgg tggaaaattt acatgtcgta
    39361 tttgatggta acaagagtcc acaagtgagt gatcactatg gcttgaatgc tatgttaaac
    39421 tggaaataat aactgaaaag aggttggaac tataaaattc cagccttttc ttactagaga
    39481 agctactgga aatagcctaa ataagtgaga ctactgtaat ggaataaaat atggtataat
    39541 tgataagata gatagaatcg aggatgttat gtcatttacg aaatttcaat ttaaaaacta
    39601 tattagagaa gccttgaagg agttaaaatt tacaactcca acagaggtgc aagacaagtt
    39661 gattcctatt gttttggcag gtcgtgacct agtaggagaa tcaaaaacag gttcaggtaa
    39721 gactcatact ttcttgttac cgatttttca gcaattagat gaagctagcg atagtgtaca
    39781 agcagtgatt actgcaccga gtcgtgagtt ggctactcaa atttaccaag tagcgcgtca
    39841 gatttcagct cactcagatg tcgaagttcg tgtggttaat tatgtgggtg gtacggataa
    39901 ggctcgccag attgagaaat tggcaagcaa tcagcctcat attgttattg gaacaccagg
    39961 ccgtatctac gacttggtta aatctggtga tttagctatt cataaagcca agacatttgt
    40021 tgttgatgaa gcggatatga ccttggatat gggattcttg gaaactgttg ataagattgc
    40081 tggcagtctt ccaaaagact tgcaattcat ggtcttctca gcgactatcc cacaaaaact
    40141 gcaaccattc ttgaaaaaat acttatccaa tcctgttatg gagaaaatta agaccaaaac
    40201 ggttatttct gacaccattg ataattggtt gatttcgacc aagggacatg ataagaatgc
    40261 tcaaatttac cagttgactc agttgatgca gccgtatttg gcaatgattt ttgttaacac
    40321 taaaacgcgt gctgatgaat tgcattcata tctgactgct caaggcttga aggttgcaaa
    40381 aatccatggc gatattgccc ctcgtgaacg caagcgaatc atgaatcagg tgcaaaatct
    40441 ggattttgag tatattgtcg caacagattt agcagcgcgt gggattgaca ttgaaggtgt
    40501 cagccatgtc atcaatgatg ccattccgca agacttatct ttttttgttc accgtgttgg
    40561 tcgtactgga cgaaatggcc taccaggtac agctattacc ctttatcagc caagtgatga
    40621 ctcggatatc cgtgagttgg agaaattggg aatcaagttt agtcctaaga tagtcaaaga
    40681 tggggaattt caagatacct atgaccgtga tcgtcgtgcc aaccgtgaga aaaaacaaga
    40741 taaacttgat atcgaaatga ttggtttggt taaaaagaaa aagaaaaaag tcaaaccggg
    40801 ttataagaag aaaattcaat gggcggttga tgaaaagcgc cgtaaaacca agcgtgctga
    40861 aaatcgcgct cgcggtcgtg cagagcgtaa agctaaacgc caaacatttt aatagaaatt
    40921 gttggagtac tgagctccaa cttttttatt tatgagaacg aactatctaa accgaaacac
    40981 tacattaaag actgcaaatt gcgattaaaa atggtataat gataaagtta tatagtcccg
    41041 ataagatggt aggtatttat tacgaagagt tttcctatca gtagtttgca attcgcaaag
    41101 aatgacggct tcgaggtcgc tcgtctttct acggttgctg ccatactgcg gtcaccctat
    41161 gcgccttact agcttcagaa ataaaaaagt atcgttttta tttctgaagc tagtaactct
    41221 tagataatgg aaattcctat cagtactttg taactctata acaatatttt ttaagggggg
    41281 acatttttat gtcagaacgt aaattattca cgtctgaatc tgtatctgag gggcatccgg
    41341 ataagattgc agaccaaatt tcagatgcga ttttggatgc tattttagca aaggatccag
    41401 aggcgcacgt tgctgctgaa acagctgtat atactggttc tgtccacgtt tttggtgaaa
    41461 tttctacaaa tgcctatgtg gatattaacc gtgtggttcg tgataccatt gcagagattg
    41521 gttataccaa tacagaatat ggattttctg ctgagacggt gggagtacac ccatctttgg
    41581 tggaacaatc tcctgacatc gctcaaggtg ttaacgaagc cttggaggtt cgtggaaatg
    41641 ctgatcaaga tccactggac ttgattggag caggtgacca agggctcatg tttggatttg
    41701 cagtagatga aacagaagag ctcatgccat tgccaattgc actcagtcat aaattggttc
    41761 gtcgtctggc agaacttcgt aagtctggag aaattagcta tctccgtcca gatgcaaaat
    41821 cacaagttac agttgagtac gatgaaaatg accgtccggt acgtgtagat acagtcgtta
    41881 tttctactca gcatgatcca gaggccacta atgaacaaat ccatcaagat gtgattgaca
    41941 aggtcatcaa agaagttatt ccatcttctt atcttgatga taagacaaaa ttctttatca
    42001 atccgacagg tcgttttgta atcggtggtc ctcaagggga ctcaggtttg actggtcgta
    42061 agattattgt agatacttat ggtggctact ctcgtcatgg tggtggtgcc ttctctggta
    42121 aagatgcgac taaggtggat cgttcagcct cttatgcggc tcgctatatt gccaagaata
    42181 tcgttgcagc agaccttgct aagaaggcag aagtgcagtt ggcctatgct atcggtgttg
    42241 cgcaacctgt ttctgttcgt atcgatactt tcggtacagg aacagtagct gaaagtcaac
    42301 ttgaaaaagc ggctcgtcaa atctttgacc ttcgccctgc agggattatc caaatgctgg
    42361 accttaagcg tccaatttac cgtcaaacat cggcttacgg tcacatggga cgtacagata
    42421 ttgatcttcc atgggaacgt ttggataagg tagatgcttt gaaagaagca gtaaaataag
    42481 attttaagag gggaacgtcc tctctttttt atagttttta actgtactgg gatactgttc
    42541 tgaaaatcca ttttgagaaa gtagagattt acatgtatag tagattgaaa ctagaatagt
    42601 acacctcaac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttctcct
    42661 gttcttgttt cattttacta tatttcttta aaaatgataa aggttgagat ttctcctcgt
    42721 aatagataat catggggata tttcaagcca aagttttatt cgttatcact tgactattgc
    42781 aaggttttct agagcaacag agtcatggaa tggactcatg gttgagattt ctccttgttg
    42841 cttggacttc attcaaaagt ctgttaccca agccttgttc aaacttccaa tacactagct
    42901 gtttccatag catgacttct gtactagact ttcttttccg aataaataga tagaaccaca
    42961 gaatctagta aacctagaat taaaattatg gtataatatt agcaataaaa gaaatctgga
    43021 ggattagaat catggtatca acgaaaacac aaattgctgg ttttgagttt gacaattgct
    43081 tgatgaatgc agcaggtgtg gcttgtatga cgatagagga gttagaagag gtcaaaaact
    43141 cagcggcagg aacctttgtt actaagacag cgaccttgga cttccgtcag gggaatcctg
    43201 agccacgcta ccaagatgtt ccacttggtt ccatcaactc tatgggcttg ccaaataatg
    43261 gcttagacta ttatttggat tatcttttag atttgcagga aaaagagtcg aaccgaactt
    43321 tcttcttatc tctggtcggc atgtctccag aggaaaccca tactattttg aaaaaagtcc
    43381 aagagagtga ttttcgtggt ctgactgagc taaatctttc ctgtccaaat gttccaggta
    43441 aacctcagat tgcctatgat tttgagacaa cagaccggat tttggcagaa gtgtttgctt
    43501 acttcaccaa acctcttgga attaaattgc caccttattt tgatattgtt cactttgatc
    43561 aagcggcagc tattttcaac aaatatccgc tcaagtttgt caactgcgtt aactctatcg
    43621 gaaacggcct ctatatagaa gatgaatctg tcgttattcg gcctaagaat ggttttggtg
    43681 gaattggtgg agaatacatc aaaccgactg ctctagccaa tgttcacgcc ttttatcaac
    43741 gtttaaatcc tcaaatccaa attatcggaa caggtggcgt tctgactggt cgagatgcct
    43801 ttgaacacat cctctgtgga gcaagtatgg tgcaggtggg aacgaccctt cacaaagaag
    43861 gcgtcagtgc ttttgaccgc attaccaatg aactgaaagc aatcatggtg gaaaaaggct
    43921 acgagagctt agaagatttc cgtgggaaat tgcgctatat tgactaaatt aaatcgaaaa
    43981 atctgaagaa aggagagacg atgctagcca ttgaagaaag tcagaagttg actttatcaa
    44041 atttaccgag cctgagccta tttacaggga cagatcaggg tcagtttgaa gtgatgaaga
    44101 gtcaagtgtt gaaacagatt gggtatgatt ctgctgacct caactttgcc tactttgata
    44161 tgaaagaagt agtttacaag gatgtggaac tggagttggt cagccttcct ttctttgcgg
    44221 atgagaaaat cgtgatatta gattatttta tggatatcac gactgctaag aaacgctttt
    44281 tgacagatga tgagcttaag tcatttgagg aataccttga caatccttct ccaacaacca
    44341 agttgataat ctttgcagaa ggaaagctgg atagcaaaag acggttagtc aaattactta
    44401 agcgtgatgc caaggtcttc gatgcagtag aagtaaaaga acaagaattg cgccagtatt
    44461 tccaaaagtg gagtcagaaa caaggtctgc agtttaccaa tcattctttt gaaaatctcc
    44521 tcatcaagtc ggggtttcaa tttagcgaaa tccagaaaaa tcttctcttt ttacagtcct
    44581 ataaggcgaa ttctgttatc gaggaagagg atattgttaa cgcaattccc aagaccttgc
    44641 aggacaatat ttttgattta actcagttta ttctgactaa aaagatggat caggcgcgcg
    44701 atttggtgag agacttgacc ttgcaagggg aagatgaaat caaactaatt gcagtcatgc
    44761 tgggacaatt tcggactttt actcaggtga agattttggc ggagtctggc caaacagaat
    44821 cgcagattgc aagtagttta ggtagttatc tgggacgtaa cccaaatcct tatcaaatca
    44881 agtttgcatt aagagattcg agaggacttt ctttgagctt tctgaagcaa gctatttcct
    44941 atttgattga gacagactat cagattaaga caggtcttta tgaaaaaggt ttcctttttg
    45001 aaaaggcact cttacagatt gctagtcagg tcaattgaca tttgttgaaa ctacaacccg
    45061 cgtcaggatt atcttgtcgt gggtttcttg ctgatttgct tatctataag caaaaaactt
    45121 gaaaaaagtg aatgtttgcg ttatcatttt catatagaaa gaaaaagagg tattacagat
    45181 ggctattatc ttaccagaac ttccatatgc atacgacgct ttggaaccat acatcgatgc
    45241 ggaaacaatg catttgcacc atgacaaaca ccatcaaact tatgtcaaca atgccaatgc
    45301 agctttagaa aaacaccctg aaatcggtga agaccttgaa gccttgcttg ctgatgtaga
    45361 atctatccca gctgatatcc gtcaagcact tatcaacaat ggtggcggac acttgaacca
    45421 cgctcttttc tgggaattga tgactcccga gaaaacagct ccttcagcag aactagcagc
    45481 agcaatcgat gcaacatttg gttcatttga agaatttcaa gcagccttca ctgcagcagc
    45541 aacaactcgt tttggttcag gttgggcatg gttggttgtc aacaaagaag ggaaacttga
    45601 agtgacttca acagcaaacc aagacacacc aatctcagaa ggtaaaaaac caatcttggg
    45661 cttggacgtt tgggaacatg cttactacgt gaaataccgc aacgtgcgtc ctgactacat
    45721 caaagctttc ttttcagtaa tcaactggaa taaagtagat gaattgtacg cagctgctaa
    45781 ataataatag ttggagggaa gaattgttct tctctttttt aggttataag attctggtat
    45841 gacaaaatcg tcagactttt ttcattttta tgagaaacgt gctaactgct agaaattatg
    45901 gtagaataaa gtattaagta atcgtggaaa aaggatatct atgcgaaaag aaattgcacc
    45961 tgaattatac aactataaca agtttcctgg tccggagttc catttacacg gggacaaggt
    46021 cgaaacggaa gggatagctt tttccttggt tgaaaatatc aaggatgcct ttgatgtgac
    46081 gacttttaat cagcgttttt cagaagtctt aaccaagttt gattatatcg tgggggactg
    46141 gagcaacgaa cagcttcgcc tacgaggttt ttacaaggat gaccgaacag aagaaaaact
    46201 tgaaaaaatc agtcgtttac aagactacct tttagagtat tgtagttatg gttgtgccta
    46261 ttttgtctta gaaaatgaag cccctaagcg agcatcattt gacaagaaaa tgcgtaagac
    46321 ggaagaagaa acaccttcta gaaaaggaaa gaaaccgact caaactaaac gaaagtcgaa
    46381 tgcagataag aaaaatagac gtcgtcagaa agaccagcat tctcagaaag aggacaaggg
    46441 acaacgtcat tttgtcattc gtcagaagtg agtagagaat aaggagaaga aatgaaaccc
    46501 tcaattcata gtttggcaca tcaaaccatg cagaaatggg tattggagca gggagaaaag
    46561 aaattccgtg cagatcaaat ctgggaatgg ctctaccgta aacgtgtgca gtcatttgaa
    46621 gaaatgacca acctttccaa ggatttgatt gctaagctca atgaccagtt tgtggtcaat
    46681 cccttgaaac aacgtattgt gcaagagtct gctgatggta cagtcaaata tctctttgaa
    46741 ttgcctgacg gtatgttaat tgagactgta ctcatgcgtc aacactatgg tttatctgtc
    46801 tgtgtgacca ctcaggtcgg ctgtaatatc ggttgtacct tctgtgcatc tggtttgatt
    46861 aagaagcagc gtgacctcaa taacggtgaa atcgtagcgc aaatcatgct ggttcagaaa
    46921 tactttgctg atgaaggggt tcaggtcaat cttgccgtgt ctcttcacgc acccaacaat
    46981 gaacttcgtt caagtatcat gaagattaac cgtgcctttc cgattgaaaa actctttgct
    47041 gctattgaat actacattga gacaacaaac cgtcgtgtaa cctttgaata tatcatgctt
    47101 aatgaagtca acgacggtgt agaacaagcc ttggaattgg ctgaattgct caagaacatc
    47161 aagaaattgt cttatgtaaa cttgattcct tataacccag ttagtgagca tgaccaatat
    47221 agccgtagtc ccaaagagcg cgtgttggct ttctatgata cgcttaagaa aaaagggggc
    47281 aactgtgtgg ttcgtcaaga gcatggtaca gatattgacg cagcttgtgg acaattgcgc
    47341 tttaacacaa tgaaacgtga ccgccagaag gcagtcgcag cggtaaatcc ttaatgatga
    47401 agaagactta taatcatatt ttggtctggg gagtcatttt ctatagcatt tgcattgtct
    47461 gtttttgctt tactcctcaa gaacaatcta ccgtgggagt gggaactcca ggtattcagc
    47521 atcttggacg cctggttttt cttttgactc ctttcaattc tctctggaaa ctgggcgaag
    47581 tgagtgacat tggacaatta tgttggattt ttttacaaaa tatcctcaat gtcttcttgt
    47641 tttttcctct gattttccaa ctcctttatc tatttccaaa tttgcggaaa acaaaaaagg
    47701 tccttctttt tagttttctt gtgagtcttg gaatcgagtg tacgcaatta atcttggact
    47761 ttttctttga tttcaatcgc gtctttgaga ttgatgattt gtggaccaac actttgggtg
    47821 gctatctggc ttggctcctt tataaacgat tacataaaaa caaggtaagg aattaaaatg
    47881 agtattttag aagttaaaaa tctgagtcac ggttttggtg accgtgcaat ttttgaagat
    47941 gtgtccttcc gtctcctcaa gggagaacat atcggcctgg tcggtgccaa tggtgaagga
    48001 aaatcaacct ttatgagtat cgtgactggt aaaatgctgc cagatgaagg aaaggttgag
    48061 tggtccaaat atgtgacggc tggttacttg gatcagcact ctgtccttgc tgaaagacag
    48121 tcggtgcgtg atgttctccg tacggctttt gatgagcttt tcaaagctga agctcgtatc
    48181 aatgacctct atatgaaaat ggctgaagac ggcgcggatg ttgatgctct catggaagaa
    48241 gtaggagaac ttcaagaccg tctggagagt cgtgatttct ataccttgga tgctaagatt
    48301 gacgaagtag cgcgtgctct tggtgttatg gactttggca tggatacgga tgtaacttct
    48361 ttgtcaggtg ggcaaagaac caaggtgctt ttggcaaaac ttctccttga aaagcctgat
    48421 atcttgctgt tggacgagcc gaccaactac ttggatgctg agcatattga ttggctcaag
    48481 cgctatctcc aaaactatga gaatgccttt gttctcattt cgcacgatat tccattcctc
    48541 aatgacgtta ttaatattgt ctatcatgtg gaaaatcaac agctgacgcg ttactctggt
    48601 gactactacc agttccaaga agtttatgct atgaagaaat ctcagctaga ggcagcctac
    48661 gaacgccagc agaaagagat tgcagacctc aaggactttg tggctcgtaa taaagcccgt
    48721 gttgcaactc gtaatatggc tatgtctcgt caaaagaaat tggataagat ggatattatc
    48781 gaactccaaa gtgagaaacc aaaaccatcc tttgatttca aaccagctcg tacaccaggg
    48841 cgctttatct tccaagccaa gaacttgcaa attggttacg accgtcctct tactaagcct
    48901 ttaaatctta ccttcgaacg caatcaaaag gttgcgatta ttggtgctaa tggtattgga
    48961 aaaacaactc tcttgaagag tctcttgggc attatctcgc caatcgctgg ggaagtggag
    49021 cgtggagatt atttagaact tggttatttt gagcaggaag tagaaggcgg taatcgccaa
    49081 actcctcttg aagctgtctg gaatgccttt cctgccctta atcaagcaga agtccgtgca
    49141 gcccttgccc gttgtggttt gacaaccaaa catattgaaa gccagattca agtattatca
    49201 gggggagagc aagccaaggt tcgtttctgt ctcttgatga atcgtgaaaa caacgtttta
    49261 gtgctggacg agccgaccaa ccatttggat gtggatgcaa aggatgagct caaacgcgct
    49321 ctcaaagaat ataggggatc tatccttatg gtctgccacg agccagactt ttatgaaggc
    49381 tggatagacc aaatatggga ttttaataat ttaacttaag aatgagagta aaagaaatac
    49441 agtaccgaat gtggatactg tatttttttg gtttttaaga tttaaaatcg tagtctttca
    49501 ccacttcgat gctgtcgatt gtgatagcag tagttggctt gtctttttca tctttttcgg
    49561 ccttagcaat cttatccaca acatccatac cgtcaatcac ttgaccaaag actgggtgtt
    49621 tgccatctag actagggttt ccaccttctt tgtaggcttc gataattttc tgtggatact
    49681 tgcttgtagg gagtttagaa gaggtatctg tagagctttg gttgatgaag aactggctgc
    49741 cattggtgtt tggttgacca gtattagcca tagcaagagc accacggatg ttatacaaat
    49801 aaggagtaat ctcgttcttg aaaccagttc ctttgtcttt agtcttatcc ttgtcatgcc
    49861 agatggactg accacctgta ccgtcccctt ttggatctcc agtttggacc ataaagccat
    49921 cgatgacacg gtggaaggta ataccgttat agtagccttc tttggcatga gtgaggaaat
    49981 tttcaaccgc tagaggagcg agtttaggga agagtttaat gcgaatatca ccttggcttg
    50041 tgtggagaat cacttcggct tcatcttcag caacttcctt agatagttgt gggaaattgg
    50101 cgttttcgtt tgttaatgca tcgtttaact ccttggcaga ttgggcagct actttggaac
    50161 tttcttcagc agcaagactg gaatcaacat aatcatcacc acgcagactg cgttggacgc
    50221 tgctacaccc agctagggct acagtagaca gtaaaagaag ggttgctagt tttttcattc
    50281 tgatcctctc aaaaattcat ttataaccat tgtaccctaa aaggaagtgg atttcaaata
    50341 ttagtagttt acagaactgg cttagataat agttgggatt tcatcatcat cttgaaaatc
    50401 ttcaacttct tccccagtaa atggtttctg aaaagaactt agtataaaac gggcaattgg
    50461 ttcaacgatt aggaaattta gaggaagagc tgcaataaag tttacgaacc aggcgcttag
    50521 ataggtattg ggtgtgatag caatgccatt gtaaaaaagt ccatagaagg acatgaaagt
    50581 gaccagctaa ttcttcttct gaaaaatgct catgaagggc ttgatccagg tcgcaagatt
    50641 tcattttaga aagtccagta actcccttct tcttcaggat attctttttc atggtattat
    50701 ttagatggtc aagtgagtca aaagaagttt cgacaagagc ataccctttt tctaccagag
    50761 tttttagatg tttaggggca tcaataccat aagtgtactc aaagtatttt ggaaaccaga
    50821 tcttaagaaa gctcgtaaag ctagccagtt ctctaaacgc taagaactag ctacaacaca
    50881 gcatttacaa cacttcatgg ttcacaccat ggggtgtttt ttaatgattt taagcaaaat
    50941 tcacacttaa ttgaaagtta tttaaattag atgaaaattt attttttgaa aaagtcggaa
    51001 aacattgatt ctaagcgaat tttgaatcat attcgaatgg gagtttttaa aatcatgttt
    51061 cagtggtaaa agtaccaaac tggattctcc atagtaaaat gatatctcct gctagtgaat
    51121 catctactaa taagtccata tttcgcttgg gaacgggctt gggacttaga agccaagtat
    51181 ccaactctcg ttcaggcgat atgaagggtt tgacttggtg ttttttataa aatttttcta
    51241 aaatagtatt cacggatagc atctttcaaa catttatttc ctattctaac aaatttctaa
    51301 atactttaag aaatttatag tctgtcaagt ttttttcttg acacatgcca gaaatctgct
    51361 ataatagaac atgtgctaaa tagctcagct atttcaccga aataaaaaat taaagaaatg
    51421 agactttaaa aatggcagtt aaaatccgtt tgactcgtat gggttctaag aaaaaacctt
    51481 tctaccgtat caacgtagca gattcacgtt caccacgtga cggacgtttc atcgaaacag
    51541 ttggaactta caacccactt gttgctgaaa accaagtaac tttgaaagaa gatcgcgttc
    51601 ttgcatggtt ggctaatgga gctcaacctt cagacacagt acgtaacatc ctttcaaaag
    51661 aaggcgtatt gaaaaaattc cacgattcta aattttcaaa ataagtttaa agtaggttga
    51721 cagatggata cgattgaaaa tctcattatt gcgattgtga aacccttaat ttcacaacca
    51781 gatgccttaa ctatcaagat tgaggataca ccagaatttt tggaatatca tttgaatctt
    51841 gatcaaagcg atgtgggtcg tgtaatcggt cgtaagggtc gcactatttc tgcgataaga
    51901 acgattgtct actctgtccc aactgaatac aaaaaagtaa gaatcgttat tgacgaaaaa
    51961 taagaagggc gggacggatg tctcgctttt ttgtgtggaa tagaagatat agtaaaatga
    52021 aacaagaaca ggacaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaag
    52081 taaaggtgta ctattctagt ttcaatatac tataaaagat tgaacgttta ggcaattcca
    52141 agactactta atcgaacatt aa
//
LOCUS       DAVHSY010000011        47190 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.011, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000011 DAVHSY010000000
VERSION     DAVHSY010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47190
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.011"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(30..776)
                     /locus_tag="VVR43_000818"
     CDS             complement(30..776)
                     /locus_tag="VVR43_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase 2C domain-containing
                     protein"
                     /protein_id="HEU6149207.1"
                     /translation="MVKINKICSIQGSSAENEDTVGSQNQYFWIIDGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYYRLPTFAF
                     IFAKLSEKKLEYMMLGDCVMLVNEMEITDHRVDNLFEKGKNEIKDSNGTNSVLNKKII
                     LQKIRKLSNQPSGYWIGSLDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTF
                     EELIKMRFNSSAIDPIYGKKDDASILVIDV"
     gene            complement(760..2838)
                     /locus_tag="VVR43_000819"
     CDS             complement(760..2838)
                     /locus_tag="VVR43_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HEU6149208.1"
                     /translation="MKSFQQNEVFSIRKSKVGVCSVLLAVLFIGTQSVLANEVVGETS
                     SSKDNMQMNSLLSSTSTSLSAEPHSDTLSLDNNSSLSTDNNGGVSINQNKPDITNDTM
                     MGNISGMEVNTILSTNLNEHVALNVKDYGAIGDGVNDDRQAIQDAIDAAAQGLGGGNV
                     YFPEGTYLVKEIVFLKSHTHLELNEKATILNGINIKNHPSIVFMTGLFTDDGAQVEWG
                     PTEDISYSGGTIDMNGALNEEGTKAKNLPLINSSGAFAIGNSNNVTIKNVTFKDSYQG
                     HAIQIAGSKNVLVDNSRFLGQALPKTMKDGQIISKESIQIEPLTRKGFPYALNDDGKK
                     SENVTIQNSYFGKSDKSGELVTAIGTHYQTLSTQNPSNIKILNNHFDNMMYAGVRFTG
                     FTDVLIKGNRFDKKVKGESVHYRESGAALVNAYSYKNTKDLLDLNKQVVIAENIFNIA
                     DPKTKAIRVAKDSAEYLGKVSDITVTKNVINNNSKETEQPNIELLRVSDNLVVSENSI
                     FGGKEGIVIEDSKGKITVLNNQFYNLSGKYISFIKSNANEKEPVIRDSDGNFNIVTEN
                     GLYKIVTNNLSDKNEKEKNKEEKQSNSNNVIDSNQKNGEFNSSKDNRQMNDKIDNKQD
                     NKTEEVNYKIVGDGRETENHINKSKEIVDVKQKLPKTGSNKIMELFLTVTGIGLLLTL
                     KGLKYYGKDK"
     gene            complement(3759..4985)
                     /locus_tag="VVR43_000820"
     CDS             complement(3759..4985)
                     /locus_tag="VVR43_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU6149209.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     QYTQTPKTVCLNSATAALELILRVLEVGPGDEVVVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDLFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPAGSIADFTSFSFHAVKNFTTAEGGSATWKANPAID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYS
                     GLLQRRKDIVDRYDRGFAGSRIHPLAHKTETVESSRHLYITHVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMANYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTSSKK"
     gene            complement(5028..5720)
                     /locus_tag="VVR43_000821"
     CDS             complement(5028..5720)
                     /locus_tag="VVR43_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU6149210.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVV
                     LVLTSPIFLIMSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     PAGITSPASIHYKDEDTIISQMTEKGLSVDQAYVEYVLPEKMRYNLAYLREFSFLGDI
                     KIMFQTVFEVLK"
     gene            complement(5904..7646)
                     /locus_tag="VVR43_000822"
     CDS             complement(5904..7646)
                     /locus_tag="VVR43_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149211.1"
                     /translation="MQNKKEQWAVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTMVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTTLVLIFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     VIKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDSVDIRAYSQEELRTNIGLVLQDPFLYHGTIKSNIAMYQEISDEQVRAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMS"
     gene            complement(7636..9381)
                     /locus_tag="VVR43_000823"
     CDS             complement(7636..9381)
                     /locus_tag="VVR43_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149212.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYTIDSFAFENEETLTNVHFSLEKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGTI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLAQV
                     YQDIVAMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGTHDDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9587..9883)
                     /locus_tag="VVR43_000824"
     CDS             complement(9587..9883)
                     /locus_tag="VVR43_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU6149213.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(10036..10491)
                     /locus_tag="VVR43_000825"
                     /pseudo
     CDS             complement(10036..10491)
                     /locus_tag="VVR43_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10625..11452
                     /gene="xth"
                     /locus_tag="VVR43_000826"
     CDS             10625..11452
                     /gene="xth"
                     /locus_tag="VVR43_000826"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU6149214.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11464..11715
                     /locus_tag="VVR43_000827"
     CDS             11464..11715
                     /locus_tag="VVR43_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU6149215.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLSL
                     EECQLMLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLY"
     gene            11722..11850
                     /locus_tag="VVR43_000828"
     CDS             11722..11850
                     /locus_tag="VVR43_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEU6149216.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHKFAVLDPNGYFLRFSE"
     regulatory      12233..12328
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12728..13309
                     /locus_tag="VVR43_000829"
     CDS             12728..13309
                     /locus_tag="VVR43_000829"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU6149217.1"
                     /translation="MKLLEDRILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13309..14571
                     /locus_tag="VVR43_000830"
     CDS             13309..14571
                     /locus_tag="VVR43_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU6149218.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPIP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14622..15083)
                     /locus_tag="VVR43_000831"
     CDS             complement(14622..15083)
                     /locus_tag="VVR43_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEU6149219.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(15080..15844)
                     /locus_tag="VVR43_000832"
     CDS             complement(15080..15844)
                     /locus_tag="VVR43_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HEU6149220.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(16025..16429)
                     /locus_tag="VVR43_000833"
     CDS             complement(16025..16429)
                     /locus_tag="VVR43_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU6149221.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            complement(16499..17980)
                     /locus_tag="VVR43_000834"
     CDS             complement(16499..17980)
                     /locus_tag="VVR43_000834"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU6149222.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPYPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNYPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(17999..19177)
                     /locus_tag="VVR43_000835"
     CDS             complement(17999..19177)
                     /locus_tag="VVR43_000835"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU6149223.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            19342..20349
                     /gene="galR"
                     /locus_tag="VVR43_000836"
     CDS             19342..20349
                     /gene="galR"
                     /locus_tag="VVR43_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU6149224.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(20395..21432)
                     /locus_tag="VVR43_000837"
     CDS             complement(20395..21432)
                     /locus_tag="VVR43_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU6149225.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(21433..21786)
                     /locus_tag="VVR43_000838"
     CDS             complement(21433..21786)
                     /locus_tag="VVR43_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU6149226.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(22030..22920)
                     /locus_tag="VVR43_000839"
     CDS             complement(22030..22920)
                     /locus_tag="VVR43_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEU6149227.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            23053..23589
                     /locus_tag="VVR43_000840"
     CDS             23053..23589
                     /locus_tag="VVR43_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU6149228.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(23756..24562)
                     /locus_tag="VVR43_000841"
     CDS             complement(23756..24562)
                     /locus_tag="VVR43_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEU6149229.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(24907..26427)
                     /locus_tag="VVR43_000842"
     CDS             complement(24907..26427)
                     /locus_tag="VVR43_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU6149230.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(26420..27148)
                     /locus_tag="VVR43_000843"
     CDS             complement(26420..27148)
                     /locus_tag="VVR43_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149231.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            complement(27163..27927)
                     /locus_tag="VVR43_000844"
     CDS             complement(27163..27927)
                     /locus_tag="VVR43_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU6149232.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(27931..28374)
                     /locus_tag="VVR43_000845"
     CDS             complement(27931..28374)
                     /locus_tag="VVR43_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU6149233.1"
                     /translation="MKYCHLVAHHIRLLNGRIFQKLLRQDPDSLYRSEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKNLEEQNLVTVSPCGEDKRKKYLVLTELGKSQ
                     KEVGQRVSQRLDTICYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(29056..29352)
                     /locus_tag="VVR43_000846"
     CDS             complement(29056..29352)
                     /locus_tag="VVR43_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU6149234.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(29374..30438)
                     /gene="pepA"
                     /locus_tag="VVR43_000847"
     CDS             complement(29374..30438)
                     /gene="pepA"
                     /locus_tag="VVR43_000847"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU6149235.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            30839..31558
                     /gene="galE"
                     /locus_tag="VVR43_000848"
     CDS             30839..31558
                     /gene="galE"
                     /locus_tag="VVR43_000848"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU6149236.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGRNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTH
                     DGSCIRDYIYVLDLHRLMLKE"
     gene            31555..31749
                     /locus_tag="VVR43_000849"
     CDS             31555..31749
                     /locus_tag="VVR43_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEU6149237.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFNLGTKKGYTIKEIFNL
                     GTKKGYTIKEIFKTAEELLN"
     gene            32046..33005
                     /locus_tag="VVR43_000850"
     CDS             32046..33005
                     /locus_tag="VVR43_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6149238.1"
                     /translation="MKLSYYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKCYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            32995..33951
                     /locus_tag="VVR43_000851"
     CDS             32995..33951
                     /locus_tag="VVR43_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU6149239.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFILANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            33948..34700
                     /locus_tag="VVR43_000852"
     CDS             33948..34700
                     /locus_tag="VVR43_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6149240.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            34796..35761
                     /locus_tag="VVR43_000853"
     CDS             34796..35761
                     /locus_tag="VVR43_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6149241.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFAKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(35986..36228)
                     /gene="yidD"
                     /locus_tag="VVR43_000854"
     CDS             complement(35986..36228)
                     /gene="yidD"
                     /locus_tag="VVR43_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU6149242.1"
                     /translation="MKRILIALVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(36228..36950)
                     /locus_tag="VVR43_000855"
     CDS             complement(36228..36950)
                     /locus_tag="VVR43_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU6149243.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(36937..37506)
                     /locus_tag="VVR43_000856"
     CDS             complement(36937..37506)
                     /locus_tag="VVR43_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU6149244.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(37525..38253)
                     /locus_tag="VVR43_000857"
     CDS             complement(37525..38253)
                     /locus_tag="VVR43_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU6149245.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLESKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(38253..38993)
                     /gene="xerD"
                     /locus_tag="VVR43_000858"
     CDS             complement(38253..38993)
                     /gene="xerD"
                     /locus_tag="VVR43_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU6149246.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISSCNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(38984..39445)
                     /locus_tag="VVR43_000859"
     CDS             complement(38984..39445)
                     /locus_tag="VVR43_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU6149247.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDSEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(39442..39963)
                     /locus_tag="VVR43_000860"
     CDS             complement(39442..39963)
                     /locus_tag="VVR43_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU6149248.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(39939..40910)
                     /locus_tag="VVR43_000861"
     CDS             complement(39939..40910)
                     /locus_tag="VVR43_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU6149249.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(40907..41701)
                     /gene="racE"
                     /locus_tag="VVR43_000862"
     CDS             complement(40907..41701)
                     /gene="racE"
                     /locus_tag="VVR43_000862"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU6149250.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(41908..42156)
                     /locus_tag="VVR43_000863"
     CDS             complement(41908..42156)
                     /locus_tag="VVR43_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU6149251.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(42412..44037)
                     /gene="treC"
                     /locus_tag="VVR43_000864"
     CDS             complement(42412..44037)
                     /gene="treC"
                     /locus_tag="VVR43_000864"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU6149252.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(44215..46182)
                     /gene="treP"
                     /locus_tag="VVR43_000865"
     CDS             complement(44215..46182)
                     /gene="treP"
                     /locus_tag="VVR43_000865"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU6149253.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            46367..47077
                     /gene="treR"
                     /locus_tag="VVR43_000866"
     CDS             46367..47077
                     /gene="treR"
                     /locus_tag="VVR43_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU6149254.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
BASE COUNT        13880 a        10706 c         8770 g        13834 t
ORIGIN      
        1 tagtaacaat taatatttta aacaatatat caaacatcaa ttactagaat acttgcatca
       61 tccttctttc catagattgg atcaatagca gaagaattaa atctcatctt aattaactct
      121 tcaaaagttt tattttgatt attttgatag aattcataaa agccatcgct cattaaaaca
      181 atttgttcac tagtaacatc tatttgatta ataatagcat ggtctaaaaa tctctcatcc
      241 aacgaaccta tccagtaccc actcggttga ttagataatt ttctgatttt ttgtaaaata
      301 atttttttat ttaaaacact atttgtacca tttgaatctt ttatctcatt tttccctttt
      361 tcaaataagt tatctactct atgatcagtt atttccattt cgtttactaa catgacgcag
      421 tcacctagca tcatatactc caactttttt tctgaaagtt tagcaaatat aaaagcaaat
      481 gttggtaagc gataatactc tgttaattca tatgagttta aaccgatttc atctttaacc
      541 tcgagtaaag cagtttcaaa tatttgttta agagtttttg attctttaca attaaccgac
      601 aaactttctg ataaaatatg tacaacttct gagactgaat aacctatctc ctctttagaa
      661 ttatataaat ctgtagctcc atcaataatc caaaaatact gattttgtga acctacagta
      721 tcctcatttt ctgcggaact tccttgtatc gaacaaattt tatttatctt taccataata
      781 cttcaaccct tttagtgtca aaagtaaacc aattcctgtc actgttaaga atagttccat
      841 aatcttgttc gaaccagtct ttggtaattt ttgttttaca tctactattt ctttagattt
      901 attaatatga ttttcagttt ctctgccatc tccaactatt ttatagttta cttcttctgt
      961 cttattatct tgtttattgt cgatcttgtc attcatttgt ctattatctt tacttgagtt
     1021 aaactctccg ttcttctggt tactatcaat tacattattt gaattagatt gtttttcctc
     1081 tttgtttttt tctttttcgt ttttatcact taagttattt gttacaattt tgtaaagccc
     1141 attctccgtt acaatattga aattaccatc gctatcacgt ataacaggct ctttctcatt
     1201 tgcattagat ttgatgaatg atatatactt accggataaa ttataaaatt ggttatttaa
     1261 aacggttatt ttaccctttg aatcctcaat aacaattcct tctttaccac cgaatatact
     1321 attctctgag actactaaat tatcactaac tcgtaataat tcaatatttg gttgttctgt
     1381 ttccttagaa ttattattaa ttacattttt tgttacagta atatctgata cttttcctaa
     1441 atattctgca ctatcttttg caactcgtat cgcttttgtt ttaggatcgg caatattaaa
     1501 tatattttcg gcgataacca cctgtttatt taaatctaat aggtctttag tgtttttata
     1561 gctataagca tttactaaag ctgctccgct ttctcgataa tgtacactct ctcctttaac
     1621 tttcttatca aagcgatttc ctttgattaa tacatcagtg aatcctgtaa aacgtacacc
     1681 tgcatacatc atgttatcaa aatgattatt taaaatttta atattagagg ggttctgtgt
     1741 cgacaatgtt tgatagtgtg tgccaattgc tgttactaat tccccagatt tatcactttt
     1801 gccaaaatag gaattttgaa tagtcacatt ttcagatttt ttcccatcat cattcaaggc
     1861 ataaggaaaa ccttttctag ttaatggttc aatctgaatg ctctccttac ttatgatttg
     1921 cccatccttc atcgttttgg gtaaggcttg cccaagaaaa cgagaattat caactaatac
     1981 atttttcgaa cctgcaattt gaatagcatg cccttgataa ctatccttga atgttacatt
     2041 ttttatagtt acgttatttg aattcccaat agcaaatgca cctgaagaat ttataagtgg
     2101 tagatttttt gctttagttc cttcttcatt caaagcaccg ttcatatcaa tagtaccacc
     2161 agaataacta atatcttctg ttgggcccca ttctacttgc gcaccatcat ccgtaaataa
     2221 acctgtcata aaaacaatag aagggtgatt cttaatattt ataccattta gaatggtagc
     2281 tttctcattc aattctaagt gtgtatgact ttttaaaaaa acaatttctt ttactaaata
     2341 agttccttcc ggaaaatata catttcctcc acctagccct tgagctgcag catctattgc
     2401 atcttgaatt gcttgtcgat catcattaac cccgtcacct attgctccat aatctttaac
     2461 attcaaagct acgtgttcgt tcagattagt acttaaaata gtattcactt ccatcccaga
     2521 gatgttaccc atcatagtat catttgttat atcaggttta ttttgattaa tactcactcc
     2581 tccattatta tcagtactta aacttgaatt gttatcaaga ctgagagtat cagaatgggg
     2641 ttccgcagat aatgatgtag atgtgctact caacaaagag ttcatttgca tattatcttt
     2701 agacgaagaa gtttcaccaa ctacttcatt agctaaaaca ctttgtgttc caataaataa
     2761 aaccgctaag agaactgagc aaactcccac cttagactta cgaatagaga aaacctcatt
     2821 ttgttgaaaa gatttcatat tagcctccaa ttaaaaatat tatgtcctaa tttaatattc
     2881 atataaattc cataccagaa aatgacaccg ctgtcatttt ctttataata tatttttaaa
     2941 tcaaaattgt caaggaataa cacaataaaa tatcaaaatt gtgaaagcgt gaccatttat
     3001 atatctaacc atacttctaa taattcttta accttccatt caaaagtgat tactatcttt
     3061 cttagcttga atataaaaat atcctattca ctgtatttaa agcatgttga catctcgtaa
     3121 aatactaatt tataaataca agaacaaata tcttgtcatg caagcattcg ccaggtatat
     3181 ttacatgaat atcgttcata tagcggattg aaatcaaaac aatacaatat atttcttaaa
     3241 tagattttct ataaaagcta gattcaagct ctataaaaat agacgcagtt cttctaaaat
     3301 actggaatag gacatataaa tcattgtaga cacgtgtttt atagattatt tcaaaagaat
     3361 gactagaaca tgaaaaatag tctcaaaact ttgaacaata ttctgaaaac aaaaaagaaa
     3421 gacgcgagtt tccacaacct catcgtggaa actcgcgtct ttcaaaaaat agggtgaatt
     3481 gaaaactaga acaagacact acattttcta aatgatgcct aataaaaatt ctaaatgcta
     3541 caccaaattg ctcacatctc atttcaaacc atacagtata ttgaaactat aagagtacac
     3601 ctttgcttct aaaatattgc tagaaattaa tttgactatc ctgattgatt tgtcctgttt
     3661 ttatttcatt ttactatagg actttcaatt gaaaacaaca gttttacact caattagact
     3721 ttttagaaac agaatcacta ttacttgact gtagtttgtc atttttttga tgaagttagc
     3781 actttttcag aaactgtttt gaaagtctca atgatatagt ccacttcttc atcacttaat
     3841 ttagtgtgaa gaggaagggt aatttcattt tcaaagaagg cataggcctt aggatagttc
     3901 gccatgtcaa aaccaagatt cttataggct gtcaagagcg gaagcggttt gtagtgtacg
     3961 ttacttgcaa ttcctgcctt ggccaattct tggatgataa gattgcgttc ttctaagctt
     4021 gctccttcta catgggtaat gtagaggtga cgtgaagatt cgacagtttc agtcttgtgt
     4081 gctaaaggat ggatgcgaga acctgcaaaa ccacgatcat agcggtccac aatgtcctta
     4141 cgacgttgca acaaaccaga gtaacggtcc aattgcacca aaccaagcga agccatgata
     4201 tcggtcatat tgcacttgta ggctggtgtg acgatatcgt attcccatga acccagttgc
     4261 atcttagcaa gagcatcctt agtttgcccg tgaagggaaa gaatttggaa ttctttgtac
     4321 atctcttcgt cgtcaatcgc tggattggct ttccaagtcg cacttccacc ttctgctgtt
     4381 gtaaagttct taacggcatg gaatgagaag gaagtaaagt cagcgataga accagctggt
     4441 tgtcctttat aagtagatcc caaagcatgg gcactatcag aaacaatcac gatacggtta
     4501 aaggcttttt gccacttgct tgaagcagta aagaggtcac gtttcttctc cactacttgg
     4561 aacaaacggt catagtcgca aacaatccct gcaagttcta ctggaatgat taccttggtc
     4621 ttttcagtga tagcttgctc cagcaagtca taatccatct caaacgtatc tgcttggata
     4681 tccaccatga caggtgttgc tcctacgtga gtgatgacac tacatgaagc tgtataggtc
     4741 atagctggaa cgacgacttc atcaccaggc cccacttcca agacgcgcaa aatcaactca
     4801 agagcggcag tcgcagagtt taggcagaca gtcttgggtg tctgtgtgta ttgagacaag
     4861 cgacgctcca attcttttgt cttaggaccg gttgtgatcc aaccagaacg aagggtatcc
     4921 gctacttcag caatttctgc ttctgtaata tcgggtggtg aaaatggaat attgtaattt
     4981 ggcattgatt tgctcctttt atctgtactc attttctcat gactacttta ttttagcact
     5041 tcaaacacgg tttgaaacat gattttgatg tctccaagga aactaaactc tcggagatag
     5101 gctaggttat agcgcatctt ttcaggtaga acgtattcga cataggcttg gtcaaccgac
     5161 agacctttct ccgtcatttg actgatgata gtgtcctcat ccttgtagtg aatgctggct
     5221 ggagaggtaa tccctgctgg caagagcaag gtcgccatca tttcagggct atactgctct
     5281 gtgtaacgag gcacttcagg acgcgtccct acaaaagaca tctcgccttt aaggacattg
     5341 accaactgag gcagttcgtc caaacgcaca cggcggatga aattaccaac cttggtaatg
     5401 cggctatcgt tagcagaagt cactagactt ccttttttat ccgcatccgt caccatggta
     5461 cggaacttcc aaatcttgaa ccgacggttg tactgggtca cgcgctcttg cttgtaaatc
     5521 actggcccct tgctatccaa cttgatccaa atgctcatga tgagaaagat gggagaggtc
     5581 agaaccagta caaccaaggc caaaacccag tccaaacaac gcttgaaaat cagcgaaccc
     5641 ttccttttag agacaagctg gtagtaagac tcaacctcgc ttgatttcat ttccacgggc
     5701 aagtcttccc atttcagcat gctgtttctc ctttgttttt attatactat ttgtcaacat
     5761 ttttcattat accacaaaat ggaaaaggcg gtgaaagaaa tctgtaattt gaaggatttc
     5821 cttcttacac tcaatgaaaa tcaaagtaca gcttttaggt tgcagataaa gctgacatgg
     5881 cttgaataga ttttcaaaga gtattaagac atggctcctg cctgcaagct atacatcttg
     5941 tgataggttc ctcccaaggc caaaagttcc tcatgggttc cgctctcgat aatgcgcccc
     6001 ttgtccaaaa catagataca gttggcgtct tggatggtag agagacgatg ggcgatagca
     6061 atggttgtcc gtccctgtct catcttagcc agagaagcct gaaccagact ttctgtttca
     6121 gagtcaatat tggctgtcgc ttcatccaaa atcaggattt taggctggct ggcgactgtt
     6181 ctggcaaagg caagaagttg acgctgacct gttgaaaaac tggagccacg ctcggaaaca
     6241 ggggaatcat aaccctgagg aagttcttga ataaaggaat ctgcatccac gaaggctgct
     6301 gcagcccgga cctgctcatc actgatttct tggtacatgg cgatattgga cttaatagtt
     6361 ccgtgataga ggaagggatc ctgcaagacc agaccgatat ttgttctcag ctcttcctga
     6421 ctgtaggccc taatatccac actatccaag agaactcgcc ctgactgaaa ttcataaaag
     6481 cgcatgagga cattgataat cgaagatttc cctgaacctg tatgacccac aaaggcaatg
     6541 gtttcaccct tattaacgga gaaggaaatg tcatccagaa tcggatgttt tccatcataa
     6601 gagaaacata catgttcaaa acggatattg ccttctttga tcacggcctg tccattttct
     6661 tgaagaggct cataggttct ctcgtcaatc agagcaaaga cacggcctgc agaaaccatg
     6721 gaagtttgaa gggttgaaaa gttttgcgtc acctcaatca aagggtcaaa gaggcggtta
     6781 atgtactgaa taaaggcata catagtcccg gcagttatcc cgatagaaaa accacggtag
     6841 ccaaagtagg ccatcaagac tgcatagcct agaagtttca gcaaactcat agcagggcgc
     6901 aaaaagaggg catccaaggc tacagaacgg ttggcataga ccaagtgctc ttggttgatt
     6961 tcatcaaatt ctgcctgcag gcgcttctcc tgattaaagg cctggattat tctgattccc
     7021 tcgatgtttt cagccagctt actattgata tctgataaga gacttctggt tttttcgata
     7081 atcttgacgg attttttccg atagagattg accaaaagga aaatcaaggg aagaaagatc
     7141 aagactaaag tcgtcaaacg aaaatccaac accaacatgg tataaagggt tgtcagaaag
     7201 atgaaaactg ctgagataaa gctggacaaa atccccgaaa acatatcact gatggtctcg
     7261 gtatcatttg tcaaacgaga gacgatagag cctgctggcg tcttgtcaaa ataggacatg
     7321 cccaatttct ccatattagc aaaggcatcc cgacgaatat ccctaacaat actgtaggac
     7381 acccgtgcaa agagaagatt accgacatac tgtaccatag tttgtaggat ataaaggcca
     7441 tagtagacca gcaaaacggt cacagcgagt tggttgagat tactcagata ctggtcaata
     7501 aagtgggaag ccacaagggg aatgacactt ttgatgaccg tcgtcgctag gagaaaactg
     7561 agtgccaaaa aagtcaggag tccataaggc ttgagataag acatcaagcg cttcaataca
     7621 gcccattgtt ctttcttatt ctgcatcttc ttctcccttc atttccagtt gctgagactg
     7681 gtaggtttgg gcataccagc catccaaagc tagcaagtca tcgtgtgtac ctcgttcgat
     7741 gatttgacca ttttgcagga ctaaaatcaa atctgcatgt acaactgcac tgaggcgatg
     7801 agccgtgata atggttgtct tgtccttacg tgtttcctta agattgtcga taatcgcata
     7861 ctctgtcttg gcatccacgg ccgacaaaga atcatccaaa atcaagatat cagggtctaa
     7921 aatcatagcc cgactcatgg ccagacgctg cttttgacct ccagaaagac tgactccttt
     7981 ttctccaatc agcgtatcaa atccctgagg catggctaca atatcttggt aaacttgggc
     8041 tagcttagtt gcttcctcga ctgctgaaag gggcaagtta ggattgccaa agcgaatatt
     8101 gtctaaaatc gaagtcgcaa agaggaactg atcctgagga acatagccca taagactacg
     8161 aagatctgtc agacgatagt cacgaatatc gtgaccattt agataaatgg ttcccttgtc
     8221 cacatcgtat tcacgcaaga ggagcttgat caaagatgtt ttcccagagc ctgtttgccc
     8281 aaccaagccc agggtttgac ctttttccaa actaaagtga acatttgtca gtgtttcctc
     8341 attttcaaag gcaaagctgt caatggtata ctccaaacgc ccattttcaa taccatccag
     8401 aggaaactca gggtcttgta caggagattc ctgagacaaa agattttcaa tccgctggta
     8461 agaaaccttc cctcgctgag tagtattaaa gaggaagccg atggccataa gaggccagac
     8521 cagcatatcc aaatagctga taaaggtgac tagattccca actgtaatct gcccttcctg
     8581 aaccatcaag gagccaacca aaagcgttaa aacataggac gaaccaacaa acacgagaac
     8641 catagggtca aagagactat catatttcat ggtttgcagg ttcttttgga aggttaattc
     8701 attgactgcc tgaaaagact tcaactcgtc tgcctgataa ccgaaagact tggtcacttt
     8761 gatacctgat acggactcct gtaccttgtt attgagttca gaaaaagcag cttgggattc
     8821 gccaaaggcc ttatgagtct ttctccctag gcgactagtt gcataggcca tgaaaggtag
     8881 ggggagaatg gcaacaagag tcatctgcca tgagatgcta aagagcatgg tcaacaaagt
     8941 caccagagcc gtgatagagg catccaccgc agacatgaca ccgccacctg ctaaacgagt
     9001 caaggcattg atatcattgg ttgcgtgtgc catcagatca cccgtccgat aggtttgata
     9061 aaaggctgat gacatttttg tgaaatgctt aaacaagcga gaccgcatga tctgtcccaa
     9121 gcaataagag gtcccaagga tatacatacg ccacacatag cgcaaatagt acataccaaa
     9181 ggctgcaagt agcaagtaaa ataggctaag aaggaggtcc tgctgggtta attgccccga
     9241 tgtgatggca tcaatgaccc gccccataac cataggagga atgagattga ggacggaaac
     9301 caagaccaag gccacaatcc cgactagata acggcgtttt tctaacttga aaaaccacca
     9361 gagtttttga ataatggaca taaaatccct ttctgatcgc aaatggaaac ctgaggccaa
     9421 tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgctc aaagcactgc
     9481 tttgaggttg tagatagaac tgacgaagtc agtaacctac atacggcaag gcgacgttga
     9541 cgcggtttga agagattttc gaagagtaca agaccccagg tttttcttat tcataagtta
     9601 cgactgtaac agcacccttg tcatattcag caataaagat attggctaca ttgtcatgcc
     9661 cttgtttgct gaggttatca agcaaccact cttcgctacg accaatcgat tccaagacat
     9721 ctacttgaat cacaccgtca gtcacaactg gatacttagg attttcatct cccatttgca
     9781 caacgatgag ttgcccattt tgctcttgca cagctcgttt gacttgcttc atctggaaaa
     9841 tcccttggct acgaagtttg agggctacat ccgatgcaga caaaccaact gaacgacagg
     9901 cttatgggtc aatattccca tttttgataa ggagagttgg cttaccatca atcaaacgtt
     9961 tcacaaagtg aacattgttg ttgagctatt tgagagtcaa gaccagtttg attaaaattt
    10021 cgatataatt aagtgtcatt tgttcacatc caccagttca attgcgtctg tcttatacaa
    10081 ttcgactttc tctaacaggt acttgtctgg ctcacttccg tttagggcac gataatagcg
    10141 atctcccacc ttgataagtg cgccatctgt gtttgtggaa gtattaacat agacttctga
    10201 cttgtctact cccaaatctt tggaaacaac ctcgatgaaa tgaagtgaag tttgaaattt
    10261 attgttagaa acttgattgt tttgataagt cgtgatgctg accaaaagca gagctaaata
    10321 aggccagagc tgaaatcatg accaactcac gaaattcggt tcccttttta tcatggtatg
    10381 ccttaaaagc aaaaaaactg tcacagctaa tagaacaatc ccaaagccaa ccatgatacc
    10441 attttgctga ccgatttggc tgagtacata gtcataagag tagaatttca tgtattttca
    10501 ctccctttca taaaatcatt cttaattata aacgaaagag agtaattttt caaactatac
    10561 gttggggaaa tagatctttt tttggtataa taaaatctat aatctgaatg aaaaaggtaa
    10621 ctttatgaaa cttatctcat ggaatattga ttccctaaac gctgccctaa ctagtgactc
    10681 agctcgtgcc aaattgtccc aagaagtcct acaaaccttg gtcgctgaaa atgctgatat
    10741 cattgctatc caagaaacca agctttctgc caaaggacct acaaagaaac acgtggaaat
    10801 tttagaagaa ctcttcccag gctacgaaaa cacgtggcgc tcttcccaag agcctgcccg
    10861 taaaggctat gctggaacca tgttccttta taagaaagaa cttacaccca ctgtcacttt
    10921 cccagaaatc ggtgcccctt ctaccatgga cttggaaggc cgcatcatca ctctagaatt
    10981 tgatgcattt ttcgtgaccc aagtttacac tccaaatgct ggcgatggtc ttaaacgctt
    11041 ggaagaacgc caagtctggg atgtcaaata tgcggagtat ttggctgaac tagacaaaga
    11101 aaaaccagtc cttgcgaccg gtgactacaa cgtagcccac aatgaaatcg accttgcaaa
    11161 tcctgctagc aaccgccgtt cacctggatt tactgacgag gaacgtgctg gatttaccaa
    11221 ccttttggca actggattta cagacacctt ccgccatgtt catggcgatg ttcctgaacg
    11281 ctacacttgg tgggcacaac gcagcaaaac ttctaaaatc aacaatacag gctggagaat
    11341 cgactactgg ctcacaagta accgtatcgc tgacaaggtc actaaatctg atatgattga
    11401 ctcaggtgct cgccaagacc atacaccgat tgtcttggaa attgacttgt aagaattttc
    11461 tatatggact acaatgcggt cattcccgag ttgcttgtat cgaatatcga acagtcccgg
    11521 tccttctact gtggtttact gggttttagg attgaatacc aacgtccaga agaaaacttt
    11581 ctctttcttt ctcttgaaga gtgtcaacta atgttagagg agggaacaaa ggatcaacta
    11641 gctgaactga cctatccatt tggtcgtgga gtcaatctct cctttggcat aaaggatgtt
    11701 tcaaaactct attaaagagt gatgaaggca aactatccta tttatcgccc cttgaccaaa
    11761 agaaagtttc gtgtcagtga tccctatatc tatcctcata aatttgcagt tttggatcca
    11821 aatggctatt ttttaagatt tagcgagtag aataataaaa attgggaaaa gtctttaaag
    11881 ttagaaaaag gcatattgtc aggtgtttaa aaacttgata gtatgccttt tatgatggaa
    11941 aaatcttcta atactcttcg aaaatctctt caagccacgt caacgtcgcc ttaccgtagg
    12001 tatatgatac tgactctgtc aattctatcc acaacctcaa aacagtgttt tgaggttgtg
    12061 gatagcttcc tagtttgctc tttgattttc atttagtata aatattagct tacaatggag
    12121 tttttgttca ccctctcttc tgtttgttcg ttttttaaac caaaacacta acaaaatagt
    12181 tgatttataa agttatttag tataaaataa aaacattggc tcaagcctat ttaaaattga
    12241 atatcgtttt acttgtttat gtcgtgaatt ggcacgacgt ttctacaagg tgccggaaca
    12301 cctaacaata agtaagtcag cagtgagata tggccgtttt tgccatgcct atttggggga
    12361 cttacttaga gattaagtag gtcttttttg aatattttta atatttccct taattagtgc
    12421 ggacgggagg tgaaattatc ctgtgaataa tttcaggaat ccagggaatt tcatccctaa
    12481 tttttgagcc cctagctctt tcatttctag gcttaggcta aaatagttcc ccgaactatt
    12541 ttactctcaa aaatcccgtc atagacaata acaagatcat tgtctatgat accactacaa
    12601 cgggaaatat ttgataagac tattacgagc gaagcgagtc ttatcaaata tatagtatta
    12661 gcaaaaggga tcactataga aacatttcaa caacaagtaa attagctttt agactttagg
    12721 aggtcttatg aaattattag aagatcgcat cctcaaggat gggcatatct tgggtgataa
    12781 catcctcaag gtagattcct ttttaaccca ccaagttgac tttagcttga tgcgagagat
    12841 tggtaaggtt tttgcggaaa aatttgctgc tgccggcatt accaaggtcg taaccattga
    12901 agcgtcgggt attgccccag ccgtttttac agctgaagcc ttaaacgttc ccatgatttt
    12961 cgccaaaaaa gctaagaaca tcaccatgaa cgaaggcatc ttaactgctc aagtctactc
    13021 ctttaccaag caggtgacca gcaccgtttc tatcgctgga aaattcctct caccagagga
    13081 caaggttttg attatcgacg atttccttgc taatggccaa gctgctaaag gcttgattca
    13141 aatcatcgaa caggccggtg ccacagtcca agctatcggt atcgtgattg agaaatcctt
    13201 ccaagatggt cgtgatttgc ttgaaaaagc aggctaccct gtcctatcac ttgctcgctt
    13261 ggatcgtttt gaaaatggtc aggtcgtatt taaggaggca gatctctaat gcaaactcaa
    13321 gaaaaacact cgcaagcagc cgttcttggc ttgcagcact tactagccat gtactcagga
    13381 tctatcctgg ttcccatcat gattgcgaca gcccttggct attcagctga gcagttgacc
    13441 tacctgattt ctacagatat cttcatgtgt ggggtggcaa ccttcctcca actccaactc
    13501 aacaaatact ttgggattgg actcccagtc gttcttggag ttgcattcca gtcggtcgct
    13561 cccttgatta tgattgggca aagccatggt agtggcgcta tgtttggtgc ccttatcgca
    13621 tctgggattt acgtggttct tgtttcaggc atcttctcaa aagtagccaa tctcttccca
    13681 tctatcgtaa caggatctgt tattaccacg attggtttaa ccttgatccc tgtcgctatt
    13741 ggaaatatgg gaaataacgt tccagagcca actggtcaaa gtctcttgct tgcagctatt
    13801 actgttctga ttatcctctt gatcaacatc tttaccaaag gatttatcaa gtctatctct
    13861 attttgattg gtctggttgt tggaactgcc attgctgcta ctatgggctt ggtggacttc
    13921 tctcctgttg cggtagctcc acttgtccat gtcccaattc cactctactt tgggatgcca
    13981 acctttgaaa tctcatctat tgtcatgatg tgtatcatcg caacggtgtc tatggttgag
    14041 tcaactggtg tttatctagc cttgtctgat atcacaaaag atccaatcga cagcacgcgc
    14101 cttcgcaacg gttaccgcgc agaaggtttg gccgtacttc tcggaggaat ctttaacacc
    14161 ttcccttaca ccggattttc acaaaacgtt ggtttggtta aattgtcagg catcaaaaaa
    14221 cgcctgccaa tctactacgc agctggtttc ctggttctcc ttggactgct tcctaagttt
    14281 ggtgcccttg cccaaatcat tccaagctcc gtcctcggcg gtgccatgct ggtgatgttt
    14341 ggttttgtat ctattcaagg gatgcaaatc ctagcccgag ttgactttgc taacaatgaa
    14401 cacaacttcc ttatcgcagc tgtttcaatc gctgcaggtg tcggtctcaa caacagtaat
    14461 ctctttgtca gcatgccgac agccttccaa atgttcttct caaacggaat cgtcgtagcc
    14521 agcctactcg ccattgtcct caatgccgta ttaaatcata aaaagaaata agaaaaagag
    14581 gtgcgagcct cttttttgtg tgacaaaata aaaacatcta cctattcata tatgctagtg
    14641 tcatagtcct gaaaatcatc tgcatcaaga acaatttcac aactcttata cttttctctt
    14701 acaagtcgtt cggcttcatc tggattttca gcctctatac ttactaaacg tgataaagtt
    14761 tctgtaattt ctactgtata ctttttcagt tttagattgc tttccaataa ttcacctatt
    14821 aacaataatc tatgatagga gctatgtagc cactctggca atttatctcc tacttcccac
    14881 ccatattttt ccttcatcaa agctagttgt ttttcgtcac caaatttcat attttcagat
    14941 aaccatctca cacaatcggg atctgataag gtacagacga ttaaacttag gttatcgtaa
    15001 cggctttcag tttcataatc aggccagatg acttttaaga aatcatacac ctcttctgat
    15061 gcaacaagtt gtttcgtttt cataatttcc gatactttcc tctaccttta aattctatta
    15121 tttctttgtc tcttaatatt tgaagctgtt gcctaatctt ttctttgata tgattgttct
    15181 taacaaagat attttttagg tcactttcaa aacgatacat atcttcaagg gtaaattctg
    15241 aaccctctat cttatctata caatttagaa tttctattgt ccaacctctt gatgacagag
    15301 agctcttcct taaaaataaa ccttgcttaa attcttttgt aactttttct ggatctctaa
    15361 cttgtccatc ttgcacaaga aatatccttc ctttagaagg tacttgtgat aaatcaatgt
    15421 tacaaccaat ccaacctgct cgtctagcag ttggtgcaag tggttttctt tgaataatcg
    15481 atttcggtgt aacaaattgc ttcggaagga caagaaagtt atttacctca aaattttttg
    15541 tgtaagttaa aaaaaagaaa ttaggattat tatctgcctg cacacgcttc atcatcgttg
    15601 cataagcacc atcattgatt gttgatgaaa aatttccttt tttgctcttt agttcaaact
    15661 cctcactaca atgattacag taaaaatctg ctacaggccg attattttca aaatgattta
    15721 agggattgtt cccacaatta gggcaataag actgacgata aacccaatcc tccgttaaga
    15781 tacgtgcctt ttggctatta cttttatagg tttctactaa ttctaaatta aagtgtaatt
    15841 ccatttaaaa attcctcact aatatgagaa ctcactcgat ataagcaatt aaaatctact
    15901 ataactagta taccacatat atgtacctat tacatttgta tttcatcact ctcttttata
    15961 tttccttcta acatatctca taaattaaaa atgagtgaga taaatttatc ccactcacct
    16021 ttctttatat acttacccgt ctttcctcag acctttggcc tgtgacaaac atggtaaagg
    16081 ttgctttaca gacatttctg ccctcttgat tggtgatatc cacatccatc acacaggttg
    16141 tacggccttg atggacacat tctcctttaa tggtcaatac atcgtcgagt tttcctgcct
    16201 taaggtagtt gatagaggat tggagtgtca ccccatcaag tcccagcgag ataaccacca
    16261 aaccactgat ttggtcacat agcgtgaata gatagccacc atgggcattg ccatagtagt
    16321 tgagcgacga gttcactact ttggtcgtca ccacaacgtg accatctctc attttttcaa
    16381 tttcgtaatt ttcaaaggca gatatagcgt caaaatgaaa gtctttcatc gtttcctcct
    16441 gatatttcaa acgacactat gatactactt tttataggac tgtgcaagga gaaagctcct
    16501 agtctagtaa aattccgaca tgttccacaa agcgcataaa ggctgtctgc ccttgttctg
    16561 tctgcttgta gactcctgca tcctcaagta cacgcgcaaa gatagcaccc acagagtcct
    16621 tgacgattgc aagggctttt tctttatccg ttaggtctgg atgttgggat ttgagttggt
    16681 ctgcccactc ctgatgataa tcggcaactg taacagcttc tcctacaaga tagctcgcga
    16741 cttgctccac ttcttctttc agacgtggtg gcaagattgc caagcccatg acctcaatca
    16801 agccgatatt ttccttcttg atatgttgga catccttgtg gggatgatag atgccatcag
    16861 gatgctctgc tgaagtctga ttgtctcgca agaccaagtc caactcaaac tgtccatcac
    16921 gcttacgcgc tattggtgtg atggtgtgat gcggtgtccc gtctgtctct gctaaaatct
    16981 gcacactaga atctgaatac tgacgccatt cctggaaaat cttatcagct aagttaatca
    17041 aatcctcttt ggaatccgaa gtcaagcgta ggacagacat tggccacttg ataattccag
    17101 ccttgacctg ctcaaaacca gcaaatcgga aggtcttttg caagggagcc aattccatag
    17161 gaaatacgtg acggcctccc tgataatgat cgtgagttag aatagagccc cccacaatcg
    17221 gcaggtcggc attagatcca gcaaaatatc ctggaaactg ctctacgata gccaacagac
    17281 gttcaaaact ctgacgacta atggccatgg gacgatgctg gccatctaaa aagatacaat
    17341 gctcattaaa gtaagcatag ggcgaatact ggaaccccca ttcctgacca accatttcaa
    17401 aacggataat ccggtggttg ctgcgagctg ggtagttgac ccgaccatgg taaccctcat
    17461 tctctaaaca aagttgacac tgaggataat tactagcttg caccaacttg gctaccgcaa
    17521 tctctttcgg atccttttca ggcttagaga gattgatggt aatttcaagt tctccataat
    17581 cagatggaac acgataagcg atatttttag caatggcctt gagtttgatg taatcatttt
    17641 tctgactgag ttgataaaaa tcctctatcg cttgctcagg agagtggaca taggcttccc
    17701 agaagtcacg attgacctga ctcggataag gagtcaccaa gtccatcagt tcagtaccaa
    17761 ggatttcacg cgcagtctga ctatcctcaa tcatctctaa tcgaacggct tcctcaacta
    17821 gctggtcctt gaggtcaatc aatttatcca gattggtctc aacttccaaa acaccttctc
    17881 ccactcgtgc caaaacacgg ttggtcaggt agattcgatc catttcctca aatgaacttt
    17941 cagaaatgac atgtgttaca aatttatcta ctaagatcac tatagagcct ccttttgact
    18001 agtcaaggac gcgagtgcca cctgcaactt cagcgatata gaagcttgga gcgtatccaa
    18061 ctacttcctc gtagtgtttg cctacagctt ccttaaaggc ctcaacagta tctttttgaa
    18121 ccaaggcaat ggcacagcca ccaaaaccag cccctgtcat acgagcaccg agaactcctt
    18181 cttgtgccca agctgtgtga acaagagtat ccaattccaa accagttact tcataatcat
    18241 gctccagaga aacgtgtgac gcattcatca aacgaccaaa tgtttccaaa tcacctgctt
    18301 gaagggctgc ttgagcttta agggtacgtt ggttttcaag cacagcatgg cgagcacgtt
    18361 tcaaacgatt ttcatcttta atcaaatagc tatattggtc aacggcccac tcgtccaatt
    18421 cacccagggt ctgaatatcc aaggcaactt gcaattcttc cactgctttt tcacactcag
    18481 cacgacgttc attgtattta gagtccgcca attcacggcg tttgttggtg ttcatgataa
    18541 caacgacatt gtccttcaaa tcaagtggca ccaagtcgta ttctaaagta ttggtatcta
    18601 agtaaatagc acgttggtca gcccccatac caatagcaaa ctggtccatg ataccagagt
    18661 tgactccgat aaagttgttt tctgtttgtt ttccgatttt aaccaaatcc aaacggtcta
    18721 gttttaaatc aaagagatgc tctgccacga ctcctgtcaa gagctccaag gatgctgaag
    18781 aagacaagcc agcaccattt gggatattcc cataaacata aaaatcaaaa cctttgtcaa
    18841 tcacgtgccc agcttcttgc aagaaatgaa gaaccccttt tggataattg gtccagttgt
    18901 gctctttttc aaacttgagg tcagcgagag gcacttcgat aatgcccttg tcctcaaagt
    18961 tagctgagta gaaacgcaag acttggtcgt cacgcttacg agctgcaccg taagttccca
    19021 aggaaatagc agcaggaaaa acgtgcccac cgttgtagtc tgtgtgttca ccaatcaaat
    19081 taatacggcc tggtgaaaag aaggtttggt ctgcttcttg accaaaaaca gcaagaaagt
    19141 ctttgcgaag gacttcagta gtaagatgtt gtgccatatg aattctcctt tgactgtccg
    19201 ttaagccatc ttaacgtgta atcgttttct ttctattgta tccaaggaat ttcccaaggt
    19261 caatcctttt tactaaaatt ttactaaaat atcagtaaaa agaagaaaaa tatgatatac
    19321 taacctaatc aaggaggatt tatggctacc ttaaaagaca ttgcacagct agcctctgtc
    19381 tctatcgcga ccgtatcccg tgtcctcaac cgcgaccaga gcctatctgt tacagaagaa
    19441 accagacacc gtattttaac cgttgctgaa gagctgggct acaccaagca cctcaagaca
    19501 ggcgagtccc ataaacccaa gcaaaagatt gccattattc aatgggtcag cgaacaaggg
    19561 gagctagacg acctctacta ctaccagatt cgcctaggaa tagaaaaaag agcccaagag
    19621 ttggactacg atatcttgcg ctattttaat gaccaccctt ttaccctaag cgaggaagtg
    19681 attgggattc tctgcatcgg aaaatttagc cgagctcaga tttctgcctt tgaagaatac
    19741 caaaagcctc ttgtatttct agacagcgat acactttccc tgggacatac ctgtattatc
    19801 acggattttt acactgctat gaaacaggtt gtcgattatt tcctcagtca agggatggac
    19861 cgcatcggga ttctaacagg gcttgaggaa acaacagacc aagaagaaat cattcaggac
    19921 aagcgtctag aaaacttcaa aaactacagt caagcgaggg gaatctatca tgatgaactg
    19981 gtctttcaag gaagatttac tgcccagtct ggctatgact taatgaagga ggccattcag
    20041 agcttgggag accaacttcc gccagcattt ttcgcagcca gcgatagttt agctatcggt
    20101 gccctccgtg ccctccaaga agctggaatc agcctgccag atcgcgtcag cctcatttca
    20161 ttcaacgaca ccagtctgac caaacaggtc tatcctcccc tctctagtat tacagtttat
    20221 actgaagaaa tggggcgagc aggtatggat attcttaaca aggaagtcct ccacggtcgc
    20281 aaaattccta gcctgaccat gctgggaacc agactgacat taagagaaag taccctaaat
    20341 caagaatagg ataacataaa aaacgaatag agttctaaaa ctcctattcg ttttttattc
    20401 gattacaatc atagacttaa ttgtcttacg ttcatccata tctttatagg cttggtcgat
    20461 atcttccagt ttataacttg aagtaaagac gcgacctgga ttgatatcac catcaaggac
    20521 ggcttttagt aaaaattgct tatcgtatgt tgtagcagaa gctgccccac ctgctacaga
    20581 gatattttgc ataaatgtcg aaccaagagc acgattatta tagtgtggga ctcctacaaa
    20641 acccatacgc cctccattat gaagaacacc tagcgcctgt tctatagcag cctccgtacc
    20701 aacacattca agtgctgcgt ctgctcctcc gccgaggatt tcacgcacct tggtaattcc
    20761 ttcttgacca cgttctgcaa caacagctgt cgcacctgac tccatagcca tcttttgacg
    20821 gtcttcatga cggctcataa ggataatttg tgatgctcca cgcatcttag ccgcgatgac
    20881 agcacattga ccaacagccc catcaccgat aacaacaacc ttgtcccctt tttgaacatt
    20941 tgcaacacgc gctgcatgat agcctgtcgg catgacatct gcaagagtca aaagggactt
    21001 gagcatccct tctgtataat cagaaggttg accagggatt ttaaccagcg cccagtttgc
    21061 atagtggaag cgaatatatt ctgcctgaaa atcacccccc aaattattac caatatgatt
    21121 gtcgcaagaa ccgtcaaatc cagcaagaca ggcatcacac tcaccacatc catgtgtaaa
    21181 agggacaatc acaaaatcac ctggtttcac cgtcgtaatg gcttccccag cttcttcaac
    21241 aatcccaatc gcttcgtgtc cactattttt atgtccagct ttcgtttctg gattacggta
    21301 cctccataaa tctgaaccac aaacgcacgc acgaaccaca cgaataatca catcatccgc
    21361 ttctattatt tgcggacgtt caatgctagc aagtccaacc tgacctgcct ttgtatatac
    21421 tgctgatttc atttaaaatt ttccttcctt ataaagttta attttgagat ttaaacgatt
    21481 taaagctgtc tgtagctgag acaagcgctc ctctaatttt tgcttttcct cttctaaaat
    21541 accaagcctc tcctctctcg tttcatctcc cttttggtag agcgacatat agtcaactaa
    21601 actatctaca gagacacccg ccgaacgaaa acacttaata aattccagcg cttcgatatc
    21661 ctgatcttga aaatcacgaa tcccagtagc agtacgagta atcggtggca caagaccaac
    21721 ccgttcataa taccgaatcg tatccgctga aattcccaac aaatcactgg cagatttaat
    21781 attcacacgc taacctcctc tcatttcatt cactgaattc acgctattct aactcactta
    21841 tcttattata taactttgag ttgactccaa gtcaagcatt ttgtatctaa tcgaaaaatt
    21901 tttatcatta acaatcatat atctggagtt tatacaatgc tcttctctta ccaatttttg
    21961 aaatatttaa ataataaaga aattactcta ttccaaataa gatagtaccc aagtattttt
    22021 cacttttttc taatgttgat gctcataact ccgttccaag tcacacacct ttcgcttatg
    22081 ggtttggtga gtttctaggt cagcatcaat ttcaatggta atattttgaa aaccacaatc
    22141 ttttaggaaa attcgaatag actctttaca agtttccata tgttccattt cttttagaca
    22201 aacatggaca atggcatttt tttccaaagc atccatagtc cagagattaa gctgattaag
    22261 gctggccaca ttgtccaatc gctccaggcc actctttact tgcttgatat caagaccttc
    22321 tggcacagca tccaagaaaa tcttgagtgt agaccaaaaa cgtggaaggg cttttgaaag
    22381 aataaagaaa gaaatgacaa gggacaaaag aggatctagg atataccagt ccgtaaatcg
    22441 aagaacaatc gccatcagga taacagctac ccaccctagc gtatcttcca gaaaatgcag
    22501 actcagaata gactcattct ttgtctttcc cttaccaacc accagactcg ctaacagatt
    22561 gatagtaatc gcaataattc ctaaccagag aatcccctca tcattgactg gttgcggatg
    22621 caaaatcttc gtgacatttt ccaaaatgac tagaacagag cccgttacga gaatcacagc
    22681 tgttaccaag gctcctagca ggctaaaccg cttatagccc aaggtgtact gattgtcttc
    22741 ttcacgattg gagattgttt ctagaaaagc tgatattcca attgcaatcg catctcccaa
    22801 gtcatgcaca gagtcagcaa gaacagcgct agaaccaaat actccacctg caataaactc
    22861 aacaatggca taagtcaaat ttaagaaaaa agccacccaa acagcatatt ttgccttcat
    22921 atttctcatt cctttgttat aatagattta tgaacacctt gttcattatc attatccact
    22981 aaaactcaaa gaaaggatag aagcaaaacg tcagctttat tcagttctga acaatttgcc
    23041 ttaagtgtcc atatgactaa cattgaccgc cgtatcagca aaaccaaaaa agccatctat
    23101 caagctttta tacaactttt gaatgctaag ggctacgagg ccactactgt tcaggatatc
    23161 attgatctcg cagatgtggg acgatccacc ttttactgtc actatgagag taaggagctt
    23221 cttctggacc agctctgccg ctacctcttc catcatcttt ttgaaagaga gcaagccatt
    23281 tcaaccgagg actacctcgc ccacctcttt ctccattttc ataaaaacca agaccatatc
    23341 accagtctgc tattttccaa aaatgactac ttcctccgtc aactccataa agagctagaa
    23401 caccatgtct attccgtgct agctgataat ttaaaagaag cccaccctaa tctgcctact
    23461 tcttacctcc aacacttggt catgtccaac tttatcgaga cattgacctg gtggctcaaa
    23521 aaaggtcaag atttcacaga ccaggaagtt gtccaatttt atctagacct tctcattcct
    23581 aaaaattgaa tatagagtaa agcttcagtt gtcttatttc taggttactg agttttttat
    23641 cttttcaaca acaaaagagg acccgccgat cctctttttc atactataaa tccttgatta
    23701 tcaactatat ctgttttaat cgaaatctca aaacagcact ttcaaacatc ttttcctagt
    23761 taagtaaatc agtattctgc ttagctgcct tgctccattg ataccaacca actagactgt
    23821 taatgagata aattagatat ttcccttgaa tttgcaggct ttctccccac cagagataga
    23881 ttgaaaagac attggtagcc gcccagaata tccactgttc acggtaaaca gctgtcatga
    23941 ggatttgccc taccccattg gttgcatctg tgattgaatc acgataggga cgattggcac
    24001 caatagactg ataaatgaag ccaaaggcca accaccaaag cacactaatg gaaagatact
    24061 ttgtccagcc cttgccgtcc agtttacgcg cgacaaactc ctgcttttcc ttcttaaact
    24121 gtgcctgata aatccaaact agaagtccaa ttggctgcat gactgtgaag taaagtgtcg
    24181 tcagcacctc accataaaag cctttctgta gggccaaaat aaggtaaata acagagttaa
    24241 tcaagccaaa aagataatta cttgctcgac cttccgatac aaagattaca cagataatcc
    24301 ctgtcaagct acaaatcatc ccaatccagt caacaatacg atgttcgtaa accaactcca
    24361 gccagagagg aaaacttcct aaaaccagca aataaatcca ctgggcaaaa ctacgatggg
    24421 caaagaggtc atcccagata gccttcatag ttcctgaaaa tcctaaatca gccatagccg
    24481 caaccatacg acggtaacca cctgacattt cacctagggt tgttttgata ttttcaattt
    24541 tcttttgcaa ataagtatgc atcatttctc cttttgtttt taaagagccg tgtctggata
    24601 gactttcgga cgcaacgctc tattagataa tgaactgcct atacacaaga tttctaacct
    24661 tagtcgacat gagctgaaac ctcttatttg ttaagtagtt cacaaaatat tatacaccta
    24721 ttttatgaat agtcaactgt ctttacagta aaattttaga aaatcatgaa aattttctct
    24781 ttctttccat tttaagtgac attcagtcat tctcacatca aaaaagccca gacgaaattg
    24841 tctgagcatt cttttatcta gtcgtttaag gaagttgagt tcagtatgtt taaagtctct
    24901 gtcccatcat ttcttcaaca aaccttgttc ttggagaaac tccttggcta cttgctttgc
    24961 tgacttgcct tcaacaccga cttggtagtt gagctggctc atctggcttt ctgtaatctt
    25021 accagccaat gtattaagaa ctctttccaa ctctgggtgt ttcttgagaa gagcttcttt
    25081 catgagtgga gccccttgat aaggtgggaa gagttgcttg tcatcttcca agacctgtaa
    25141 atcataacgc tccaattccg catcagtcga ataggcatcc gtgatttgaa tatcccctga
    25201 ctgaattgcc tgataacgaa gagctggctg catagtcgcc acattgagat tgagaccata
    25261 cattgattgc aagcccttat ttccatcttc acggtcgtta aactcaagcg taaagcctgc
    25321 cttcagctgc ccttccactt ttttcaaatc cgaaatggtc ttcaagccat attcttgagc
    25381 aatctttttc ggaacagcta cagcataggt attttgataa gacataggtt tgagataggc
    25441 tagatgatcc tgcttggcaa tgccatcacg cgccacttga taaacctgct ctggctcatg
    25501 actcaccttg ggtgatggtt gaagcaaact ttcagtcacc gtaccggtaa attcaggata
    25561 aatgtcaata tcaccttttt tcagagcttc ataaaggaaa cttgtcgtcc caaaattcgg
    25621 tttaacagtc gcagtcatgc tggtattttc ttcaatcagc aatttataca tattagccaa
    25681 aatttctggt tctgggccta ttttcccagc aataatcaag ttttccttct ctttttgagc
    25741 caaaagggct ggactataag acagacccag taataaagcc accaaggcaa aaccagagaa
    25801 aatcgtccgc aatttcgctt tttccattac ttttagtagg aagttaaagg caatagctag
    25861 cactgcagaa gaaagggccc caatcaaaat caaactggca ttattacggt caattcccaa
    25921 caggataaag gaacccagtc cccctgcccc aatcaaggtc gccaaggtag ccgtaccgat
    25981 aatcaagacc gctgccgtcc gaattccaga catgataaca ggcatggcaa gtggaatttc
    26041 aaacttcttg agacgctccc atctggtcat cccaaaggca atcccagcct cttgaagact
    26101 cggatcaatt cccttcagcc cagtaatagt attttgtaaa atcggaaaaa tcgcataaat
    26161 cactagagct gtcaaagccg gcaaggtccc aattcccatc aaagggataa agagccccaa
    26221 caaggccaga gacgggatgg tctggaaaat acctgcaatc tgcaagaccc agtcggccag
    26281 cttctcatga tagcgaagaa aaacagccaa gggaatcgca agcaaaatag ctagtaacaa
    26341 ggtcaaaagt gacaactgca aatgttgaga tagagctgtc aaccaatcac taaaacgatc
    26401 ctgaaaagtt gcaattaaat tagtcatgaa cactacctcc aaacaagtct gctacaaagt
    26461 ctgttgcagg cacttttaaa attgtctcgg gattcgctac ctggcgaatt tctccatcct
    26521 gcaagacagc aatacggtcc gccaacttca aggcttcatc cgtatcatgg gttacaaaaa
    26581 tcgttgtcat cccaaactct ttatgcaatt cttttgtcag aacctgcaac tgttttctcg
    26641 aaatagcatc caaggccgaa aagggttcat ccatgaggaa aatcttgggc tgaccaatca
    26701 tagctcggac aataccgacc cgttgctgtt ctccaccaga taattcacta ggtaagcgat
    26761 gcccatactc ggctactggt aaaccaacct tagccaaaag ctcttctgtt ttcttcgtaa
    26821 tttcttcctt gctccacccc ttcatttcag gaatgagagc aatattttcc gcaactgtta
    26881 gatttggaaa aagagcaata gcctgtaaaa cataaccagt agaaagacga agttcacgct
    26941 catcatagtc tttgatgcgc ttcccatcca tataaatatt tccatcagtt ggttccaaaa
    27001 gacggttaat catcttgagc atggtcgtct tacctgaccc agaaggccct actaaaacca
    27061 taaattcccc atcctcaatc tgtaagttga catctctcaa gacatccttt tctgtgtagc
    27121 gcagtgctac atttttgtat tcaatcattc tttgtcctca atttaaaact tccctcgatt
    27181 agtcaagtct tctaccttag gcatgacttc cttattatcc caatgctcca caattttccc
    27241 gttctctaaa cggaagatat cgtactgggc ataagcaacg ccatcaatct gagtctgacc
    27301 atagctaacc acatagtttc cttgtcctaa gagttggaaa acaaagtcaa aagtgacact
    27361 atattcagcc acatagtttt tataagcagc acttccttgt ccaatctcat gattatgctg
    27421 aatcaaatcg tctgccacat aatcactcca ctgctctagc tccccatttt ggaaaatttc
    27481 tgtcaagaaa cggcgaacca gttttttatt ttctgctttc ttgtccaaat ccttgatttc
    27541 aaaatctcca aaaatttgat ctagttgatc attttcaggt gttcgatagt agtcaatgac
    27601 atcccaatgc tcaacaatac gaccattctc atccgcacgg aaagtatccg tcgtcaccca
    27661 ttgagcttct ccaccattca gatattgatg aacatgaaca aagaccagat tgccatcctc
    27721 aatggtgcgg acaatcttaa tctgacgctc tggatgacgc tcaaagaaat ctgcaaagaa
    27781 ggctgcaaat ccttctttcc cgtcaggaac acctgtcgaa tgttggatat aggtatcccc
    27841 tacagactgg gcttgagcct cagcaactcg tccgtcttga atggcatgga tgtataggtt
    27901 gtgagcattt ttcacttgtt gtgacatatt ctaaacctca tttcccttct ctttcaaatt
    27961 cgccaaaatt ctttcttgaa aaccttcaaa ttggtgaatt tcttcctctg aaaatccttt
    28021 gtaacagata gtatccaatc tctgactgac acgttgccca acttctttct gggacttgcc
    28081 caactctgtt aaaactaaat acttcttacg cttatcttct ccacacggac tgacagttac
    28141 aagattttgt tcctctagat tttttatcat agtcgtcagc gtattattag caagcccagt
    28201 cgcaagcgca atgtctgtcg ccgtagcaca gcctgtctca ctattccata aaaccgctaa
    28261 aatctttccc tgctcactcc gataaagaga gtcagggtct tgtcttagta acttttgaaa
    28321 aatccgccca ttcaacaaac gaatatgatg ggctaccaaa tgacaatatt tcatgaaacc
    28381 tccaatttat ttctatatcg aaatagataa agtgattata acactcatca ttccatatgt
    28441 caactatttc gatttagaaa taatttttga taattattta catcaccata ctccggatca
    28501 actaactttt aaggagagtt tctaaactcc ttcgtcctcc agtctacaaa agcctttcat
    28561 ccgtactatc ctatatttta tgaggggaca catttttcct atcagaccat ttattttaaa
    28621 gatagaagta aatcataatt gcttccatct gttcttttat agtatattga agttgaacta
    28681 ggacactgta tcttctaaaa cattgataaa aagcgacttg aatttcccaa tcaatttgtt
    28741 cgtatttata gcatttcgaa actggaatag gacaccatga ctgctaaaag atttctataa
    28801 attcatttga tttccctaat caatttgttc atatcttatt tcattccgct ataatttcac
    28861 cttaccctat ctttttcgta gcacccttca aacagcctat cccctaccgt ttgacgattc
    28921 ctcacttcac tccacttcca ttacagaagt ttcttcacta ctatggtctc ggctgacttc
    28981 tcatgattcc ttgttactac tatttgaacg ctcacgagat aggtcttata aaaaatgctt
    29041 tgatccacaa tggaatcaaa gcattttaaa aagttcctca tacataagcg cagaagtcgc
    29101 agttcctctg tacttggctt cttctctttt gataaagcga gccaagttga gcaactcagg
    29161 tgctggatgt ttgggattta ggagcaattc acgattgacc aggcctgaga gacgaactgc
    29221 ctgcaattgc tcatttgtag taggcagttt tttagtagtc tctaggagag cagcaactaa
    29281 atcttcactc aaatcatgtc gagcatgatt gtaaagatct tttataaggc tttctaggtt
    29341 tggttctacc atccctacca cctcccttat ggtttaataa tgtttaatca aatcaaccgt
    29401 tgaacgatcc aatttcttca ccaaggcttg taagaaagct tgcgcttcta ggaagtcatc
    29461 cattgcatag agggtttggt gagaatggat ataacgagcg cagacaccga tagttgttga
    29521 tgggacacca ccatttttca gatgagctgc acctgcatct gttccgcctt taccacagta
    29581 gtattggtac ttgataccag cttcttcagc cgttgtcaaa aggaaatcct tcatccctgg
    29641 aagaagcaag tgacctggat catagaaacg aatcaaggtt ccatctccaa tcttgccttg
    29701 accaccgtag acatcacctg ctggtgagca atcaactgcg aggaagactt ctgggtcaaa
    29761 cttggttgta gaggtatgag cgccacgcag accaacttct tcttggacgt tagaacccag
    29821 atagagttca ttgccgagtt tttgacctga taaagcttca gctagctcgc ttaccatgag
    29881 gacaccgtag cggttatccc aagcttttga gatgatattt ttttcattgg ctgtcaaaat
    29941 tgcagaacta tctggtacga tggtatcacc aggacggatg ccaaaacttt ctgcctcagc
    30001 cttgtccgca aaaccaccat caaaaacgat atcggcaatg gctggcatgg ttggtccccc
    30061 ctttccacga gtcaaatgcg gaggaacaga acctgaaatc acaggaattt catgaccatc
    30121 acgagtcaag agtttgaaac gttggctgct aaccaccatg gggttccagc caccgatttc
    30181 tacgacacgg aaggtaccat ctggcttgat ttcgctgacc ataaaaccaa cttcgtccat
    30241 atgagaagcg accaagacgc gcggtgcatc cacagcttct gaatgtttga taccaaaaat
    30301 accacccaag ccatctgtca ccacttcatc cacatgcggt gtcaactttt cacgaagata
    30361 agcacggaca ggcgcttcat gacctgagac tgcagcaagt tctgttactt ctttaatttt
    30421 tgaaaataat gttgtcattt cagttccttc tttctttcat ccattttacc actttttata
    30481 ggagaaggat agtgggaagg tggatttcta agttagtatc ttagtcctgc tctatcttag
    30541 aaaaggatag tattctcttg catgtagtgc aaaatctagt aaacattcca aaattaactc
    30601 gaatatttat ttccaaacaa aaaaacaata caccatcaaa gttgtttaga ttttttatga
    30661 aatttacaga aaatagttga cttccctttc ttctttcttt aaatatatag ttggttgagt
    30721 ttggaatagt acgctgtagc tgctaaaaca tttctagaaa ttaatttgac tttcctaata
    30781 gagttgttca tatcttattt caatttacta tagtacaaaa ctagaaaagg aaaaaatcat
    30841 gaccaaaaca attcttgtta caggtgggac tagctacatt ggctcccata ccgttaaagc
    30901 tcttttaaat gctggctata aggtgcatgt cctcgataat ctctccacag gaaatcgagc
    30961 ggctgtggat agtcgtgcta gctttaaaga actggatgtt tatgatgcta gcgccttaaa
    31021 ggcttactta gaagaaaatc agattgatgc tgtcctccat tgtgcaggtg aaattgttgt
    31081 gagcgaaagt attgaaaatc caagtaaata cttcactgcc aacgttgctg gtaggaacca
    31141 agttctcaaa gtcttatctg aagttggcat tcaaaaaatc atgttctctt cgactgcttc
    31201 tctctatgga aataactgta ttgacaagcc ggtgactgaa gataccctgc tcgaccctgt
    31261 caacccttat gcagagacaa aactgatggg cgaacgaatg atttactgga tggccaatcg
    31321 ctacgactgg aaatatgtta ttttccgtta ctttaatgtt gctggggctg aaatggatgc
    31381 ttcaaacggt ctgcgtgtga aaaatccaac tcacatcatt ccaaatatca acaagaccgc
    31441 attgggacaa aatgatagct taaaaatatt tggagatgac tacgatacac atgacggttc
    31501 atgtattcga gattacattt atgtcttgga ccttcatagg ctcatgttaa aggaatgaac
    31561 tacctatttc aagaagacag ttcttctcaa atctttaact taggaactaa aaaaggctat
    31621 actatcaaag aaatctttaa cttaggaact aaaaaaggct atactatcaa agaaatcttt
    31681 aacttaggaa ctaaaaaagg ctatactatc aaagaaatct ttaaaactgc tgaagaatta
    31741 ctaaattaaa aaatcccaca cgagattgtt gctcgacgtg ctagtgaccc agccagtgtc
    31801 ctagcagatg cttcaaaagc taaacaatat cttgattgga cggctagcta ctccctcgaa
    31861 gatattattt tatcagatta aggtaaaaac attttagaat aggataacaa aggagaaagt
    31921 cttgttgctc tctccttgtt gtatttatta aattgtcaga aattttattg acagattaga
    31981 aaaataatgt tacatttata tccgcagata tctttcgata ccaaatctac atgaaaggac
    32041 ggggtatgaa actttcttat tatttaattg gcttacttct actcctagtc tttctctcta
    32101 ttagcattgg gaccagtgat ttttcatggg gaaagctatt tgatttcgac cagcagacct
    32161 ggctcctctt tcaagagtcc cgtctcccaa gaactatcag tattctcctg actgcctcta
    32221 gtatgagtat ggcaggcctt ctcatgcaga ctattaccca aaatcagttt gctgcaccga
    32281 gtacagttgg aacgactgaa gccgccaaac tgggaatggt gctgagcctt tttgtctttc
    32341 catcggctag tctgacccaa aagatgctct tcgcttttgt ttcatccatc gtattcaccc
    32401 tcttcttcct agcctttatg accattttta ctgtaaagga aaggtggatg ttgcctctga
    32461 ttgggatcat ctatagcggg attatcggct cagtcacaga agttatcgcc tatcgtttca
    32521 atctggttca gagtatgact gcctggaccc agggctcctt ctccatgatt cagacccatc
    32581 agtatgagtg gctcttctta ggcctcatca tcctgataac cgtttggaaa ttatcccaaa
    32641 ccttcaccat catgaatcta gggaaagaaa ccagcgagag tttggggatt tcctactccc
    32701 tacttgaaaa actggccctc tttctggtgg cgctaacgac aagcgtcacc atgattaccg
    32761 tgggtggcct accatttctc ggagttatcg ttcccaatct tgttcgcaag tgctatggag
    32821 ataatctaag tcaaaccaaa ctcatggtcg cactggttgg tgccaatcta gttctggctt
    32881 gcgatatcct atcccgagtt ctgattaggc cctatgagtt gtctgtcagt ctcttgctag
    32941 gaatcatcgg tagtctcgtc tttatcctac ttctctggag agggggacga aaagatgcag
    33001 actaaaagca aacataccaa gctcttctgg attctcatta ttcttgccat cggagcttgt
    33061 cttctctact tttggcccat cactcacttg tcagcctttg cttggaagtt gcgttcccaa
    33121 aagatcatcg tttatctctt ggtagccatc gcgactggga tttcgaccat tagttttcaa
    33181 accctgacgg aaaatcgctt cctgacgcct agtattttgg gaattgaatc cttctacgtc
    33241 ctactacaaa ccctactact ggtttttgaa agcaagtttc ttcaacttgg caaatcccct
    33301 atcttagaat tcctagtctt acttcttgtc cagtccctct tctttctcgc cttacaaggt
    33361 tacttgaaga cactgatgaa gcaagacctg gtcttcatcc tgctgatctg tctagcgctc
    33421 agaagtctct ttcgaaatat cagcaccttc cttcaagtcc taatggatcc aaacgaatac
    33481 gataaactgc aaaatagtct ttttgcctcc tttcaacatc tcaacacttc catcctagcc
    33541 atcggttctc tgatcatcct cgctttgaca atctttttct ttcgaaaagc agtcgttcta
    33601 gatgtcttgc acctgcaaag agaaacggct cagatattgg gactcgatgt tgaaaaagaa
    33661 cagaaagagc tcctctgggg aatcgtgctt ttgacctcaa cggccactgc cttggtagga
    33721 cctatggcct tcttcggctt tatactggcc aacctcacct acctgattgt caaagactat
    33781 cagcacaagt tactctttat agtggccatt ctggttggat ttattagctt aaccttgggg
    33841 caagccttga ttgaacgagt ctttgcactg gaaattcgta tcagtatgat cattgagagt
    33901 gtgggtggct tcttattctt tatcttacta tataggaggt ctcgtcagtg aaactggaaa
    33961 acattgacaa atccattcaa aaacaggata ttttgcaagg catttcgctt gaagtcagtc
    34021 ctcaaaaact gacagccttt attggtccaa atggtgctgg aaaatcgact ctcctctcca
    34081 tcatgagcag gctaaccaag aaagatcagg gagttctcag tatcaaagga cgtgaaatcg
    34141 agagctggaa ttcgcaagaa ctggcccaag aactaaccat cctaaaacag aaaatcaatt
    34201 accaagccaa attgactgtt gaagaactgg tcagttttgg acgttttccc tacagccgag
    34261 gtcgacttag atcagaagac tgggaaaaaa tccgagaaac tctgaactat ttagaactga
    34321 ccaacttaaa agaccgctac atcaatagcc tgtcaggggg gcaactccag cgcgtcttta
    34381 tcgctatggt actggcccag gatacggact ttatcttgct ggacgaacca ctcaacaatc
    34441 tcgatatcaa gcaaagcgtc agcatgatgc agattcttcg acgactggtg gaggaactcg
    34501 gcaagaccat tatcatcgtc ctccacgata tcaacatggc cagtcagtat gcagatgaaa
    34561 ttgtcgcctt caaggacggc caggtcttta gcaagggaag aaccgatcaa atcatgcagg
    34621 ctgacctgct cagtcaactt tatgagattc ccatcacgct agctgatatc aatgacaaaa
    34681 agatctgtat ctatagctag taacataaaa gctcaagtta gagaaccttc agtctcttag
    34741 tcaataagat taagagactc cctaaatcgt tatcacattt taaaaaggag aaattatgaa
    34801 aacatccctt aaactttatt tcactgccct agtggccagc ttcttgctcc tacttggtgc
    34861 atgtagtaca aactcaagca ctagtcagac agagaccagt agctctgctc caacagaggt
    34921 aaccattaaa agttcactgg acgaggtcaa actttccaaa gttcctgaaa agattgtgac
    34981 ctttgacctc ggcgctgcgg atactattcg cgctttagga tttgcaaaaa atatcgtcgg
    35041 aatgcctaca aaaactgttc cgacttatct aaaagaccta gtgggaactg tcaaaaatgt
    35101 tggttctatg aaagaacctg atttagaagc tatcgccgcc cttgagcctg atttgattat
    35161 cgcttcacca cgtacacaaa aattcgtaga caaattcaaa gaaatcgccc caaccgttct
    35221 cttccaagca agcaaggacg actactggac ttctaccaag gctaatatcg aatccttagc
    35281 aagtgccttc ggcgaaactg gtacacagaa agccaaggaa gaattggcca agctagacaa
    35341 gagcatccaa gaagtcgcta ctaaaaatga aagctctgac aaaaaagccc ttgcgatcct
    35401 ccttaatgaa ggaaaaatgg cagcctttgg tgccaaatct cgtttctctt tcttgtacca
    35461 aaccttgaaa ttcaaaccaa ctgatacaaa atttgaagac tcacgccacg gacaagaagt
    35521 cagctttgaa agtgtcaaag aaatcaaccc tgacatcctc tttgtcatca accgtaccct
    35581 tgccatcggt ggggacaact ctagcaacga cggtgtccta gaaaatgccc ttatcgctga
    35641 aacacctgct gctaaaaatg gtaagattat ccaactaaca ccagacctct ggtatctaag
    35701 cggaggcgga cttgaatcaa caaaactcat gattgaagac atacaaaaag ctttgaaata
    35761 agccacttca aactcaattt aatactcaat gaaaatcaaa gagcaaacta ggaaactagc
    35821 cgcaggttgc tcaaaacact gttttgaggt tgcagatgaa agctgacgcg gtttgaagag
    35881 attttcgaag agtataaaat tttgacattc taaaacgcat cctatcaagt tcactcaaac
    35941 ctgataggat gcgtttttat cattttgaaa tctatttacc ccacctcatt ccccttcttg
    36001 atttcgttta agggaaaagt ggtctggaac ggggtcctta cctgttttcg accagggatg
    36061 acaacgtaaa atccgagcca agcccatcaa taccccctta aaaccatgtt tttcaatagc
    36121 ctgaatcatg tagttggaac aagtcagctc aaagcgacaa gagggtggaa agactggtga
    36181 gataaaacgt tggtaaaagc gcacaagcgc tattaaaatt cgtttcatta tttcttagtt
    36241 acagccatgg tgtgtagttg gctgatttct tttttattaa gacgacggga ttctcctgga
    36301 cggagtcctg tcaagtctag gtgtccgaaa cgagtccgag acaacttatc tacttggaga
    36361 ccaacagctt caaacatctt tttaacctga tggttacgcc cttcatggat ggtcaactgc
    36421 accacagagc gatttttgac tgggtccact ttgagaattt cataaacagc tggcttggtt
    36481 ttcttaccat caatctcaag accacgggtc aaggggcgaa gattgtcctt attggccaca
    36541 cctttaacac gcgcgacata aaccttgtca atctcattac gagggtgaat catctcgtct
    36601 gtaaagtccc catcattggt caaaatcaag actcctgatg tatcccagtc taaacgaccc
    36661 acagggtaaa tacgctcttt gacattgggc aagaggtcga caaccgtctt gcgaccctta
    36721 tcatctgtca cactggaaat gacaccgcgt ggtttgttaa gcagatagta gaccttttct
    36781 tcgttgtaga taggttgacc ttcaacttcg accttgtcgc ctgacttgat agtggttgct
    36841 agttcacgca ccacttggcc gttaaccgtc accaagcctt gcttaatcag ctcttctgct
    36901 tttctcctac tggccacacc tgcgtgggca atatacttat tgattctcat cttcttctat
    36961 cctttcacca aataattggc tttcttgggc ttgaatctca agctcatcaa tcactggtaa
    37021 ttcttctaaa tggtttatcc ccatgtaatc taggaaataa tccgtagtca catagaggtt
    37081 ggggcgcccc aatacttcct ttttcccgtc ttcctttatc aggtcaaaag cctgcaactt
    37141 tgccaaggct ccactcgagt taactccacg gatggcatca atttctatcc gcgtaatcgg
    37201 ctgtttgtag gcaataatgg acaaggtctc aagggcagcc cgagacaagc tctggttgat
    37261 aggcgcctta gagtattcct tcaaaatctc tgcaaattga ggcttggtca ccaatctata
    37321 agcaccactt gtctcaatca aagccaaact ggaatctggg tccttttcat acttctgggc
    37381 taattttcct aaactttgct ggatgcctgt cggtggcaga gagaggagtt cagctaactg
    37441 gcggacccga atcccatctt cacccgctac aaacaagagc gcttctattt ttgctaaagt
    37501 actcatcttt cctctctatc aagtctagct ttgaggcact tgactttctt ccttcttttc
    37561 catgagatag atatctccga aactctcctc ttgcacgagg atcagctcct gggttttgat
    37621 taactctagg gttgccaaaa agagggtgat gacctcttgg acattctggg cttccttgaa
    37681 caaatcctgc aagcgcaatt gatctcgtcc aatcaaggac tctttcacga taatcatcat
    37741 gtcctcaatc ttatactcat cccgcaagat agtcgtgtga ttttgtgcaa actcctcttt
    37801 tttcttggct aggatatttg aaaaagccaa aaagaggtca atggtcgtct tgtcatgcac
    37861 aagctccgca tcttcgtaaa tcaactctgt cggcgctttg gaataatact gggcccgttc
    37921 ttggtgcttg gattccaagt gctcacccaa gagcttgaac ttgcgatatt cttcgatttg
    37981 agagaggagg tcctgctcca ggtcatcccc caagtctgtc acttctgcta ccttcggaag
    38041 gagtttacga ctcttaatca gcatgagctg actagccatg accatgtact cacccgtcac
    38101 ttccagacgc atggcctgca gggttgagac ataggctaga tactgttcga tgacttccgt
    38161 aatgggcaca tcgtagatat ccatctggta cttagaaacc agatgcaaga gcaagtccaa
    38221 gggtccttca aaatctttta atttaatatc cattatctat atttttctaa ggtcaggact
    38281 gtttttaatc ctaatttttt tgcaatttcg tacaaatcga ccttgttttc tatttgtctt
    38341 agaataaact gttcacgtaa gacttgagct gataaggatg gaaaaccttt ctccttgaca
    38401 aaagattcta actgacgaaa ggcccactga cgagaatagg gtttctctcc tctttcaaaa
    38461 agataggtct gccccatcaa gggttccaat tctgaaagca aggccgtggg aatggtgaca
    38521 atcctctgtt gggaagcctt gctgattcgc aacacctgaa aatccagatt gatgtccgca
    38581 accttgatgg ctaaaatctc actgggcaag agccccattt ctaggattaa gagcgctagc
    38641 aagcggccct ctggatggtc gctttcctgc caaaaagagt ctaggtatag aatctctggc
    38701 ttttccgtct tcttttcagc ttgtttggct aattccaagc ggtaaaagct gtccacctct
    38761 cctttttgat agagaaagta tagaaattgg ttacaggacg aaatctttcg cttctgggcg
    38821 ctgattttta gattggctag ctgggcttgg taaatcttga gactggtctc agaaatccgc
    38881 tcacctacca tgtctaaaaa ttgctccaaa tcatacttat aggactgctt ggaattgaca
    38941 gacaagccct gcttttcctc taaaaaggct gaaatcctgt ctctcattgg catcgaatct
    39001 catattcctt actaaagtca tgcaagaggg cattaacggc cttgaggatg gacttgcgcg
    39061 taataatccc ttggaaaata ccctctgaat ccacaaccgg taagaaggac tcatctacta
    39121 gcttgtgcaa gacctccgta atggtgaaat caggcgaaac aaccgctacg tccgtttttg
    39181 tcatatgaac gatatccgta tccgccatga tttcttggct caagtcatgc tccatctgat
    39241 aagccataat atctctgagt ccaatcgtcc caacaaactg tttttcatct gtcacaacgg
    39301 gaacacgggt ataggtcatc tgactgagca agagggtcgc atgatccgca ttgtgggtat
    39361 caatcaacac agctagattt ttagcagggg tcaaaaaagt ttcctcctgc cccaacaaga
    39421 aagtctcaaa ctccttggca atcatcggct aaactccttg gacaaacctg gatacacctc
    39481 gtgatctcgt gtcaaaaagt ccactttgaa gtaactatca tcaatctcca cacgagcata
    39541 gagacattct ctgatggtac ctcgtggttg actgatagaa cctggattta gaaagaggat
    39601 cttgccttcc atccaagcac ttggcacatg caagtgacca tagaggcaga tagcggcctc
    39661 ttcctcctga gcccagtagt ccaacttttg aaagttgaaa ttgatgtcaa acaagtgacc
    39721 atgagtttgg ataatcttgg tcgaaccaag ctcagtcacc agacgttctg ggtagccggc
    39781 gtagaagtcc atgttccctt taacaacgcg gatgccctcc caaagtggag aatccggacg
    39841 tagttcagaa tcgccgttat gaaaaacggc atcgactttg cccacatagc gatcacggac
    39901 ttcttccaca atcaagctat cgccatggga atcgctcatt acaatgatgg tttgctttgc
    39961 catgatggaa atacctccaa aagtttctta acggctaagg cacggtgaga ttgactattt
    40021 ttttcttcca gggttaattc agctgatgac tcacctgtct ctcctacaag gaagagggga
    40081 tcatagccaa agccattttc acccttaggt tcaaagttaa tataacctga ccagtctgct
    40141 tcaacaacta aactttcctt atttgggctg gctacgacta gggttgtgtg gaactgagcc
    40201 gagcggtcct tgagttcaaa gaccatggcc aattcgtgca agagtttggc attattttca
    40261 cggtcagttg ctcccacacc tgcgaaacga gctgaccaga cgcctggtaa gccaccaagg
    40321 acatcgactt tgagaccaga atcatctgcc aaaaccatct tgcccgttaa ttgagaaatg
    40381 gtttctgcct taaggcgggc attttcttca aaggtcatac ctgtttctgc tacttcaggc
    40441 aggtcagggt agtcattaag attttccaca tcgtagccta acttatcaaa gatagctcgg
    40501 aattccttgg ttttaccttc gttacgagtc gcaatcaaca aggtttctct gaccttgctt
    40561 gtctcaaaga aatcatgaac attgacccct tctttaggca attctacata caagagttgc
    40621 ccattttcaa ccaagagcag ggccccatga cgttgaataa cttccaagtt tcgtcccatt
    40681 tcttgattaa gcatgtctac cacaaaggag aacaaacggt aggtagaacc atagcgtaaa
    40741 acagtaactg aaagcgggaa accatactct tcatctccaa atattttgga gaattcaaac
    40801 agaggaaaat ctgtcttata gtcgctcaaa ctgttaacgc caccaaaaat actataagac
    40861 ccaacatacc agtcctggtc atccttatat tcataaattt tatttgtcat aattctacat
    40921 gctccacatg aatctctttt tccagccatt cttcaccaat ttgtgcaaaa ctttggctac
    40981 tggctgttgt gtaaaaacgg tgatggagtg gtccagcatc gcgaccacga ttgatttcaa
    41041 aataattgag taagactgag atatcccgta cgcactctgc cccactatcg atgagctgaa
    41101 cctttggccc catcacattt tggataatag ggcgaaggag tggataatga gtacagccca
    41161 aaatcaggct atccaccttt ccaaccaagg gacgcagggt ttcatagacc accttcttgg
    41221 taacactggt tgacagggca cctgactcaa ccaagggagc aaacttggga caggccaagc
    41281 tctccacctg taagtcggga tccagatcat ggattttctg acggtatatg tctgattgta
    41341 ccgtcatggg cgttccaatc actccgattt tcccaccttg actggacttg atggctgccg
    41401 aagctcctgg caaaattaca cccaagacag gaatatctag ttgagccttg atttcttccc
    41461 agacgaccgc agtcgcagtg ttacaagcaa tgacaatcat tttgacatcc ttggtcaaga
    41521 gaaagttgac cagctgccaa gtatattcac gaatttgctc agcaggacgg gggccatagg
    41581 gcgcccgcgc cgaatctcca atatagacga tttcttcatg gggaagctgg cgcatgagct
    41641 cgcgcacaac ggtcaagccc ccgacacccg aatccaaaaa accaattggt cgattatcca
    41701 tacagtcttc tttctagtct tttttctgat tgatcgttca ttatgattcc ttgtactgaa
    41761 cgaactgacc gacagcttga tagaatgtca actacctctc tcttaatcat aatcaaatat
    41821 caatagaatg caaggaaaaa gtctcatccc taaaccataa ccaacatagt gagaagtctg
    41881 gaactttcat cccagacttt tccttattta ttttttcttt ttattgttag caagggctgc
    41941 cttttgttgg cggatgattt ggtggtaaac ttgttgtacc ttagcttcgc ttggtttttg
    42001 accatttgca ctcaaaagag tacgaactgc ttcagcattc aaacgtgggt tgtcagcaaa
    42061 ttctttttcg atttgcttac gaaccaagta cattcctcca agagctcctc ctagaaaagc
    42121 tagcacaatc aatacaattg ctaaaagtaa atccatcatt tttctcctgt ttctttttga
    42181 atccctttca ttataccaca aactagccac cctgaccagt ttgttctaca ctttcaagga
    42241 tggaatagac agcaaaaaga accctgcttt tctgaaaaag aggtctcctt gctaagttta
    42301 tactcaatga aaatcaaaga gcaaactagg aagctagcca caggttgctc aaagcaccgc
    42361 tttgaggttg cagataaaac tgacacggtt tgaagagatt tgcgaagagt attaatttac
    42421 ataaatagcc agtgtttgat agggtttgag tagaattttc tcagacactt ctgcatcttc
    42481 atagtttgat atcaaaatct gtccattttg gtagactgct ggcaagtcga tttccacttc
    42541 tttagcataa aagttattga gcactagtaa cttttgatcc tcaaactggc gttcaaaagc
    42601 gtagacttgt ttgctatctt caaaggctgg tttgtaactt ccttctgaaa tgattggcat
    42661 ttccttacgc agtcgaatca agtcttgata gaaggtaaaa atcggaccct ggatttcatt
    42721 ttctacattg atgtctttat aggatttacc agctttcaac caaggagtgc ctgttgaaaa
    42781 tcctgcattt tccgaagcat cccactgcat gggaatgcgt gaattatcac gcgacttagc
    42841 ttgaataatc tggaaggctt cttgctgact ctttccttct tctaagagca tctgataggc
    42901 attaagcgat tcgacatcca cataatcagc catagaatca tagtctgggt caatcatccc
    42961 gatttcctca cccatgtaga tataaggtgt cccacgtgac aggtgaatgc tggccgctag
    43021 catggtggct ccttccttgc ggaagttttg aatatcgaca aaacggttca aggcacgtgg
    43081 ttgatcgtga ttgttccaaa agagggcact ccaaccgtct ttatcactca tttccttacc
    43141 ccaactatgg taaagactct tcaactcttc aaaatcaaag ggagccaagg tccacttttg
    43201 tccatcctta tagtccacct tgaggtgatg aaaattaaag gtcatggata attcctgacg
    43261 atcaggcgac gaataaagga cacagttttc catggtggta gaagacattt ccccaactgt
    43321 cataaagcta tcgtcagatc caaaagtggc ttggttcatc atacgcaaat agttatgaac
    43381 gatgggtttg tctgtataag ctggcttccc ttcattttca ggacagtcca ctgaaacctc
    43441 gtccttaccg atcaaattga tcacatcaaa tcggaaacct ttgataccct tgtcgcgcca
    43501 gaaattaaca accttgaaaa gctccttacg gacattggaa ttgcgccagt taaggtcagc
    43561 ctgggtctca tcaaataggt gaagatagta tttcccagta tccccgaaag gcgtccatgc
    43621 agaaccacca aacttagact gccaatctgt tggttggtct tggatgaaga aaaagtcttg
    43681 ataatactta tcaccagcta gggctttctg aaaccattca tgctctgtcg aacaatgatt
    43741 aagtaccatg tccagcataa agtcaatctt gtgctcttta ccgacacaca ccatttcctc
    43801 aaaatcagcc atatcaccaa aaagaggatc cactgccata taatctgaaa tatcgtaacc
    43861 attatcccgt tgagggcttg gatagaatgg attgagccag accatatcca cacctagttt
    43921 ggctaaatag ggaatttttt cgataatccc acggaaatcc ccaataccgt tttcagtggt
    43981 gtctttgtaa gattttggat agatttgata gactactttt cctttatcaa gtgtcatctg
    44041 tttctccttt tctgataaaa gggaggaagc agtcttccgt ccctatttgt gctatttcaa
    44101 ttatactcaa tgaaaatcaa agaacaaact aggaagctag ccacaggttg ctcaaaacac
    44161 tattttgagg ttgcagatag agctgacgtg gtttgaagag attttcgaag agtattagat
    44221 tcgtgtagcg accatgagag atgctccagc ttggatcgtt gtcggataag ttccgggaat
    44281 agtcgctgta taagcatctt ggttggtgat gataacagga gtttctgtca ccagacctgc
    44341 agccttaatg acatccatat caaaacgaat cagttgctga ccaactgtaa cgtgatctcc
    44401 ttggactaca agactttcaa aacctttgcc atcaagacct actgtatcca taccgatgtg
    44461 gatgagcaat tcaactccct cgtcagagac aatgccgatg gcatgcttgg tagggaaaag
    44521 aaccgtcact gtcccattaa ctggagaggt caactcacct tggcttggtt caatgaccag
    44581 accttgcccc atgacacctg atgcaaaaat aggatccgtc gcttgactca attctttcac
    44641 ttggccagtt agtgggctga taatttctac cgaagtaagt tctactggtt catggttcac
    44701 aaattctgct tcttcttgag caacgaattc tgcctgcaag ttcgtatcgc cctctgtttt
    44761 tgtaaagaga ccagccttgc ggaagaagaa agtcaagagc attggaacaa caatcgcaac
    44821 tagcatagtt cctgcaaatg gcagcatgta ttgaggttga atagagagaa tacctggcaa
    44881 accaccgata ccaatagaag ccgcagttac attaaaagta acggataaca tgcctgcaag
    44941 ggctgaacca gtcatcccag caacaaatgg ataaatatat tttacgttaa ccccaaaaag
    45001 agctggttct gtaacaccga gataggctga aatggttgca ggaagtgaaa cctgagcctc
    45061 acgctcatca tggcgatgca tgaaataata ggcaaacacg gctgagcctt gagcaatatt
    45121 agaaagagca atcattggcc agagggcagt gccaccagca tccgcaatca attgtgtatc
    45181 aatggcattg gtcatatggt gcagacctgt gatgacaaat ggagcgtaga gggcaccaaa
    45241 aattgcaccg aagagccatt taactggacc agttaaacct gccaagacaa ctgatgaaag
    45301 tccttgtcca attgtccaac cgattggtcc caaaacagta tgagccaaaa tcaaggctgg
    45361 aatcaatgac aaaaaaggta caaaaatcat ggaaatgact tctgggatat gtttgcgcca
    45421 gaaaatttca agataagaca gactcaaacc tgcaagcaag gctgggataa cttgggcttg
    45481 gtaaccaata cgattaacag taaaataacc aaaattccaa acccagtttg ctgcgatatc
    45541 agctgctggc gttgaagcaa ccgcataggc attgagcaac tgaggcgata ccaaacagat
    45601 tccgagaaca attcccaaaa tttggctggt tcccatctta cgagaaacag accaagtaat
    45661 ccctactggt aagaactgga agatagcttc accaggcaac cagaggaagt gattaacccc
    45721 tgcccaaaac tgagaggatt ctgtgatggt cttgccatcc aacatcgacc aatggacacc
    45781 ttccaagaca ttacggaaac cgaggatcaa tccaccaaca atcaaagctg gaataatcgg
    45841 agtaaagatt tccgccagag tggtcataac acgttggacc acgttttgat tactcttagc
    45901 tgcagacttg gctgcttctt tagaaacacc ctcaatacct gaaacggctg taaaatcatt
    45961 ataaaagatg ggcacgtcat ttccaatgat tacctgaaat tgacctgcat ttgtaaaagt
    46021 tcctttaaca gctggaattg actcgatagc tttaacatta gccttcttat catctcctaa
    46081 aacaaagcgc atccgtgtcg cacagtgagt tacggcagtc acattttctt tgcctccaat
    46141 tgcctgaagc agatctttgg cttcttgttc aaattttccc atttgattct ccttatactt
    46201 gtcaaagcaa gtttgatttg ataagtatat tgtaaacgat accaaacttg tctgcaactt
    46261 gtttggtata aaaagggtgt ttttttgtaa attttctagc acttgtatgg taaaatagat
    46321 acaggtgttc attaaactag actaaaaacc tatttaagca ggcaaaatga agaaatacca
    46381 acaattattt aagcaaatcc aagaaaccat tcaaaacgag acttacgctg tcggagattt
    46441 ccttcctagc gagcacgacc ttatggagca atatcaagtg agtcgtgata ccgtccgaaa
    46501 ggccctgtct ctcctccaag aggaaggatt gatcaaaaag ataagagggc aaggttctca
    46561 agtcgtcaaa gaagaaaccg tcaatttccc tgtatccaac ctaaccagct accaagaact
    46621 agttaaagaa cttggactgc gctctaaaac caacgtggtc agtctggaca agattattat
    46681 tgataaaaaa tcctcactga taaccggttt cccagagttt cggatggttt ggaaggtggt
    46741 ccgccagcgt gtggtggatg atctggtatc cgttctggat acagactatc tggatatgga
    46801 actcatccca aatctcactc gccaaattgc tgagcagtct atctattctt atatagaaaa
    46861 tggcctcaaa ctccttattg attatgctca gaaggaaatc accattgacc actcaagcga
    46921 ccgagacaag attctcatgg acattggcaa agacccttat gtcgtttcga ttaaatcaaa
    46981 agtctatctc caagacggac gccaatttca gtttaccgaa agtcgccata agttagagaa
    47041 atttagattt gtagattttg caaaacgcaa gaaataaaag actgagacac cagatctcag
    47101 cctttttcgg ctctataata tttgtagtgg gtaacccccc ctatagatat tatggagcct
    47161 attttattgt agaaaaaaag tcccataaga
//
LOCUS       DAVHSY010000012        42527 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.012, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000012 DAVHSY010000000
VERSION     DAVHSY010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42527
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.012"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            152..4090
                     /gene="strH"
                     /locus_tag="VVR43_000867"
     CDS             152..4090
                     /gene="strH"
                     /locus_tag="VVR43_000867"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU6149255.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKEEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETETGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSHLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(4145..5443)
                     /gene="purB"
                     /locus_tag="VVR43_000868"
     CDS             complement(4145..5443)
                     /gene="purB"
                     /locus_tag="VVR43_000868"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU6149256.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(5506..5733)
                     /locus_tag="VVR43_000869"
     CDS             complement(5506..5733)
                     /locus_tag="VVR43_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEU6149257.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            complement(5743..6834)
                     /gene="purK"
                     /locus_tag="VVR43_000870"
     CDS             complement(5743..6834)
                     /gene="purK"
                     /locus_tag="VVR43_000870"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU6149258.1"
                     /translation="MSSSKTIGIIGGGQLGQMMATSAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            complement(6821..7309)
                     /gene="purE"
                     /locus_tag="VVR43_000871"
     CDS             complement(6821..7309)
                     /gene="purE"
                     /locus_tag="VVR43_000871"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU6149259.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            complement(7712..8974)
                     /gene="purD"
                     /locus_tag="VVR43_000872"
     CDS             complement(7712..8974)
                     /gene="purD"
                     /locus_tag="VVR43_000872"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU6149260.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTAIYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            complement(9096..10643)
                     /gene="purH"
                     /locus_tag="VVR43_000873"
     CDS             complement(9096..10643)
                     /gene="purH"
                     /locus_tag="VVR43_000873"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU6149261.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            complement(10668..11177)
                     /locus_tag="VVR43_000874"
     CDS             complement(10668..11177)
                     /locus_tag="VVR43_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU6149262.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEILFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            complement(11261..11806)
                     /gene="purN"
                     /locus_tag="VVR43_000875"
     CDS             complement(11261..11806)
                     /gene="purN"
                     /locus_tag="VVR43_000875"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU6149263.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            complement(11803..12825)
                     /locus_tag="VVR43_000876"
     CDS             complement(11803..12825)
                     /locus_tag="VVR43_000876"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU6149264.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGLHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            complement(12862..14304)
                     /locus_tag="VVR43_000877"
     CDS             complement(12862..14304)
                     /locus_tag="VVR43_000877"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU6149265.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            complement(14397..18122)
                     /locus_tag="VVR43_000878"
     CDS             complement(14397..18122)
                     /locus_tag="VVR43_000878"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU6149266.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELKAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVVSDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            complement(18179..18886)
                     /locus_tag="VVR43_000879"
     CDS             complement(18179..18886)
                     /locus_tag="VVR43_000879"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU6149267.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNVAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            complement(19056..20405)
                     /locus_tag="VVR43_000880"
     CDS             complement(19056..20405)
                     /locus_tag="VVR43_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU6149268.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKVTASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKYVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            complement(20418..22571)
                     /locus_tag="VVR43_000881"
     CDS             complement(20418..22571)
                     /locus_tag="VVR43_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU6149269.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            complement(23286..23516)
                     /gene="blpU"
                     /locus_tag="VVR43_000882"
     CDS             complement(23286..23516)
                     /gene="blpU"
                     /locus_tag="VVR43_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU6149270.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(23719..24009)
                     /locus_tag="VVR43_000883"
                     /pseudo
     CDS             complement(23719..24009)
                     /locus_tag="VVR43_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(24055..24288)
                     /locus_tag="VVR43_000884"
     CDS             complement(24055..24288)
                     /locus_tag="VVR43_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU6149271.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(24294..25286)
                     /gene="plsX"
                     /locus_tag="VVR43_000885"
     CDS             complement(24294..25286)
                     /gene="plsX"
                     /locus_tag="VVR43_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU6149272.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(25283..26053)
                     /gene="recO"
                     /locus_tag="VVR43_000886"
     CDS             complement(25283..26053)
                     /gene="recO"
                     /locus_tag="VVR43_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU6149273.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGTCLCPEHYHEDERRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(26050..27219)
                     /locus_tag="VVR43_000887"
     CDS             complement(26050..27219)
                     /locus_tag="VVR43_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6149274.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGECYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            27368..28378
                     /locus_tag="VVR43_000888"
     CDS             27368..28378
                     /locus_tag="VVR43_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU6149275.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDVGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWNSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILHFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            complement(28536..28616)
                     /locus_tag="VVR43_000889"
                     /pseudo
     CDS             complement(28536..28616)
                     /locus_tag="VVR43_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(28651..29088)
                     /locus_tag="VVR43_000890"
     CDS             complement(28651..29088)
                     /locus_tag="VVR43_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU6149276.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(29173..31806)
                     /gene="polA"
                     /locus_tag="VVR43_000891"
     CDS             complement(29173..31806)
                     /gene="polA"
                     /locus_tag="VVR43_000891"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU6149277.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            32062..32412
                     /locus_tag="VVR43_000892"
     CDS             32062..32412
                     /locus_tag="VVR43_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU6149278.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            32627..32743
                     /locus_tag="VVR43_000893"
     CDS             32627..32743
                     /locus_tag="VVR43_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU6149279.1"
                     /translation="MVGVFRQQTLYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            32736..32969
                     /locus_tag="VVR43_000894"
     CDS             32736..32969
                     /locus_tag="VVR43_000894"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149280.1"
                     /translation="MFSQLHMREEQVLLAQDYASETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            33097..33378
                     /locus_tag="VVR43_000895"
                     /pseudo
     CDS             33097..33378
                     /locus_tag="VVR43_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(33512..34480)
                     /locus_tag="VVR43_000896"
     CDS             complement(33512..34480)
                     /locus_tag="VVR43_000896"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU6149281.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(34625..35440)
                     /locus_tag="VVR43_000897"
     CDS             complement(34625..35440)
                     /locus_tag="VVR43_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEU6149282.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPD
                     STFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLI
                     FLGLALGTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(35465..35962)
                     /locus_tag="VVR43_000898"
     CDS             complement(35465..35962)
                     /locus_tag="VVR43_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU6149283.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(36035..37396)
                     /gene="radA"
                     /locus_tag="VVR43_000899"
     CDS             complement(36035..37396)
                     /gene="radA"
                     /locus_tag="VVR43_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU6149284.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINETAKLGFTKIYVPQNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(37410..37925)
                     /locus_tag="VVR43_000900"
     CDS             complement(37410..37925)
                     /locus_tag="VVR43_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU6149285.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(37927..38370)
                     /locus_tag="VVR43_000901"
     CDS             complement(37927..38370)
                     /locus_tag="VVR43_000901"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU6149286.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(38427..38524)
                     /gene="ffs"
                     /locus_tag="VVR43_000902"
     ncRNA           complement(38427..38524)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VVR43_000902"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(38557..39024)
                     /locus_tag="VVR43_000903"
     CDS             complement(38557..39024)
                     /locus_tag="VVR43_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU6149287.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSKESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(39225..40511)
                     /locus_tag="VVR43_000904"
     CDS             complement(39225..40511)
                     /locus_tag="VVR43_000904"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU6149288.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(40742..40978)
                     /locus_tag="VVR43_000905"
     CDS             complement(40742..40978)
                     /locus_tag="VVR43_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU6149289.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            41244..42041
                     /locus_tag="VVR43_000906"
                     /pseudo
     CDS             41244..42041
                     /locus_tag="VVR43_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(42076..42285)
                     /locus_tag="VVR43_000907"
                     /pseudo
     CDS             complement(42076..42285)
                     /locus_tag="VVR43_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(42451..42524)
                     /locus_tag="VVR43_000908"
     tRNA            complement(42451..42524)
                     /locus_tag="VVR43_000908"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42488..42490),aa:Asn,seq:gtt)
BASE COUNT        12540 a        10244 c         7961 g        11782 t
ORIGIN      
        1 tctgaaatct taagtttaaa ttttatattt ttttatactt attatagttt tttgtcatct
       61 cctcttgact ctcgttaata taagaaataa aataaaggcg ttgatttata taatcgctat
      121 caatataaca atgcaatcag gaggttttgc aatgaaacat gaaaaacaac agcgtttttc
      181 tattcgtaaa tacgctgtag gagcagcttc tgttctaatt ggatttgcct tccaagcaca
      241 gactgttgca gccgatggag ttactcctac tactacagaa aaccaaccga ccatccatac
      301 ggtttctgat tcccctcaat catccgaaaa tcggactgag gaaacaccta aagcagagct
      361 tcaaccagaa gctccaaaaa ctgtagaaac agaaactcca gctactgata aggtagctag
      421 tcttccaaaa acagaagaaa aaccacaaga ggaagttagt tcaactccta gtgataaagc
      481 agaggtggta actccaactt ctgctgaaaa agaaactgct aataaaaagg aagaagaagc
      541 tagccctaaa aaggaagaag cgaaagaggt tgattctaaa gagtcaaata cagacaagac
      601 tgacaaggat aaaccagcta aaaaagatga agcgaaagca gaggctgaca aaccggaaac
      661 agagacagga aaggaacgtg ctgcaactgt aaatgaaaaa ctagcgaaaa agaaaattgt
      721 ttctattgat gctggacgta aatatttctc accagaacag ctcaaggaaa tcatcgataa
      781 agcgaaacat tatggctaca ctgatttaca cctattagtc ggaaatgatg gactccgttt
      841 catgttggac gatatgagca tcacagctaa cggcaagacc tatgccagtg acgatgtcaa
      901 acgcgccatt gaaaaaggta caaatgatta ttacaacgat ccaaacggca atcacttaac
      961 agaaagtcaa atgacagatc tgattaacta tgccaaagat aaaggtatcg gtctcattcc
     1021 gacagtaaat agtcctggac acatggatgc gattctcaat gccatgaaag aattgggaat
     1081 ccaaaaccct aactttagct attttgggaa gaaatcagcc cgtactgtcg atcttgacaa
     1141 cgaacaagct gtcgctttta caaaagccct tatcgacaag tatgctgctt atttcgcgaa
     1201 aaagactgaa atcttcaaca tcggacttga tgaatatgcc aatgatgcga cagatgctaa
     1261 aggttggagt gtgcttcaag ctgataaata ctatccaaac gaaggctacc ctgtaaaagg
     1321 ctatgaaaaa tttattgcct acgccaatga cctcgctcgt attgtaaaat cgcacggtct
     1381 caaaccaatg gcctttaacg acggtatcta ctacaatagc gacacaagct ttggtagttt
     1441 tgacaaagac atcatcgttt ctatgtggac tggtggttgg ggaggctacg atgtcgcttc
     1501 ttctaaacta ctagctgaaa aaggtcacca aatccttaat accaatgatg cttggtacta
     1561 cgttcttgga cgaaacgctg atggccaagg ctggtacaat ctcgatcagg ggctcaatgg
     1621 tattaaaaac acaccaatca cttctgtacc aaaaacagaa ggagctgata tcccaatcat
     1681 cggtggtatg gtagctgctt gggctgacac tccatctgca cgttattcac catcacacct
     1741 cttcaaactc atgcgtcatt ttgcaaatgc caacgctgaa tacttcgcag ctgattatga
     1801 atctgcagag caagcactta acgaggtacc aaaagacctg aaccgttata ctgcagaaag
     1861 cgtcgcggcc gtaaaagaag ctgaaaaagc tattcgctct ctcgatagca accttagccg
     1921 tgcccaacaa gatacgattg atcaagccat tgctaaactt caagaaactg tcaacaactt
     1981 gaccctcacg cctgaagctc aaaaagaaga agaagctaaa cgtgaggttg aaaaacttgc
     2041 caaaaacaag gtaatctcaa tcgatgctgg acgcaaatac tttactctga accagctcaa
     2101 acgcatcgta gacaaggcca gtgagctcgg atattctgat gtccatctcc ttctaggaaa
     2161 tgacggactt cgctttctac tcgatgatat gaccattact gccaacggaa aaacctatgc
     2221 tagtgatgac gttaaaaaag ctattatcga aggaactaaa gcttactacg acgatccaaa
     2281 cggtactgca ctaacacagg cagaagtaac agagctaatt gaatacgcta aatctaagga
     2341 catcggtctc atcccagcta ttaacagtcc aggtcacatg gatgctatgc tggttgccat
     2401 ggaaaaatta ggtattaaaa atcctcaagc ccactttgat aaagtttcaa aaacaactat
     2461 ggacttgaaa aacgaagaag cgatgaactt tgtaaaagcc ctcatcggta aatacatgga
     2521 cttctttgca ggtaaaacaa agattttcaa ctttggtact gacgaatacg ccaacgatgc
     2581 gactagtgcc caaggctggt actacctcaa gtggtatcaa ctctatggca aatttgccga
     2641 atatgccaac accctcgcag ctatggccaa agaaagaggg cttcaaccaa tggccttcaa
     2701 cgatggcttc tactatgaag acaaggacga tgttcagttt gacaaagatg tcttgatttc
     2761 ttactggtct aaaggctggt ggggatataa cctcgcatca cctcaatacc tagcaagcaa
     2821 aggctataaa ttcttgaata ccaacggtga ctggtactac attcttggtc aaaaaccaga
     2881 agatggtggt ggtttcctca agaaagctat tgagaatact ggaaaaacac cattcaatca
     2941 actagcttct accaaatatc ctgaagtaga tcttccaaca gtcggaagta tgctttcaat
     3001 ctgggcagat agaccaagcg ctgaatacaa ggaagaggaa atctttgaac tcatgactgc
     3061 ctttgcagac cacaacaaag actacttccg tgctaattat aatgctctcc gcgaagaatt
     3121 agctaaaatt cctacaaact tagaaggata tagtaaagaa agtcttgagg cccttgacgc
     3181 agctaaaaca gctctaaatt acaacctcaa ccgtaataaa caagctgagc ttgacacact
     3241 tgtagccaac ctaaaagccg ctcttcaagg cctcaaacca gctgcaactc attcaggaag
     3301 cctggatgaa aatgaagtgg ctgccaatgt tgaaaccaga ccagaactca tcacaagaac
     3361 tgaagaaatt ccatttgaag ttatcaagaa agaaaatcct aacctcccag ctggtcagga
     3421 aaatattatc acagcaggag tcaaaggtga gcgaactcat tacatctctg tactcactga
     3481 aaatggaaaa acaacagaaa cagtccttga tagccaggta accaaagaag ttataaacca
     3541 agtggttgaa gttggcgctc ctgtaactca caagggtgat gaaagtggtc ttgcaccaac
     3601 tactgaggta aaacctagac tggatatcca aaaagaagaa attccattta ccacagtgac
     3661 tcgtgaaaat ccactcttac tcaaaggaaa aacacaagtc attactaagg gcgtcaatgg
     3721 acatcgtagc aacttctact ctgtgagcac ttctgccgat ggtaaggaag tgaaaacact
     3781 tgtaaatagt gtcgtagcac aggaagccgt tactcaaata gtcgaagtcg gaactatggt
     3841 aacacatgta ggcgatgaaa acggacaagc cgctattgct gaagaaaaac caaaactaga
     3901 aatcccaagc caaccagctc catcaactgc tcctgctgag gaaagcaaag ctcttcctca
     3961 agatccagct cctgtggtaa tagagaaaaa acttcctgaa acaggaactc acgattctgc
     4021 aggactagta gtcgcaggac tcatggccac actagcagcc tatggactca ctaaaagaaa
     4081 agaagactaa gtcttttcga taaaaaataa acagcgagat tgaagctcgc tgtttatttt
     4141 ttaattaatc acctagtcca agacgttcaa agatatcatc cactcgtttg gtgtaataaa
     4201 ctgggttgaa gatttcatcg atttcttctt gagtgagacg tgatgttact tctgaatctg
     4261 cctcaagaag tggtttaaag tctacttggt tgtcccaaga gtaggctgtt tttggttgca
     4321 ccaagtcata ggcttgctca cgggtcatgc ctttttcaat caatgtcaac atagcccgtt
     4381 ggctaaagat aagaccaaaa gtcgagttca tgtttcggat catattttct gggaagactg
     4441 tcaagttctt gacgatattt ccaaaacggt tgagcatgta gtcaatcaaa atggtcgtat
     4501 ctggtgtgat gatacgctca gctgatgagt gagaaatatc gcgttcgtgc cagagagcga
     4561 cgttttcata agccgtaatc atgtgaccac gaatgacacg cgccagacca gtcatatttt
     4621 cagaaccgat tgggttgcgt ttgtgaggca ttgctgaaga ccctttttgc cctttagcaa
     4681 agaactcttc tacttcgcgt tgctcagatt tttgtagacc acgaatctca gtcgccatac
     4741 gttcgattga agtcgcaatg ctggcaagaa ccgcaaagta ctcagcgtga aggtcacgag
     4801 gaaggacttg tgtagagatt tcttgggcac ggatgccaag tttatcgcag acatactcct
     4861 ctacaaatgg tgggatattg gcaaagttcc caaccgcacc agaaatctta ccagcttcta
     4921 caccagcagc tgcatgctcg aaacgctcga tattgcgttt catttcgctg taccaagttg
     4981 ccaatttaag accaaaggtt gtcggctcag cgtgcacacc atgagtacgc cccatcatga
     5041 tggtgaactt gtgctccttg gccttgtcag cgatgatatt agtgaagttt tcaaggtcac
     5101 gacggatgat gtcgttggcc tgcttgtaga ggtaaccata agcagtatcc accacgtcgg
     5161 tagaagttaa cccatagtga acccacttgc gctcttcacc aagagtctca gaaaccgcac
     5221 gcgtgaaagc caccacatcg tggcgcgtct cctgctcaat ttccaaaata cggtcgatgt
     5281 caaagtccgc cttcttgcga atcaaagcca catcttcctt agggatttcc cccaactcag
     5341 cccatgcctc gtcagagagg atttccacct caagccaagc acggtattta ttttcttcac
     5401 tccaaatatt cgccatctca gggcgagagt aacggttgat catgtgttaa tttttccttt
     5461 cttcttaagc tgttgggaat aagctatcta ggtaaaccaa gatttctact caaactcctc
     5521 tttttcaata aacacagacg ggtaatgatc tagtgtattc aaatccgtat ccagcggtac
     5581 atcatagata gctaaataat tttcggggta ttgtgcagct agttcttcat atttagcttg
     5641 taccttatct tggtcagcac tggcatacaa cacttcaaca actgctccag tcttatcctt
     5701 ttcaataaat gtattaacga taatttgtat catagacttg tcctaaaaat caatcccttc
     5761 cccaagctca tccacactat ccggtacatc actaaacaag gtcacatgtc ccatcttgcg
     5821 gttgtgcttc gcttctattt taccatacat gtggaggtgg gcgcttgaat tttctgtcac
     5881 atattgctca gcagcctcga catgctgacc gaggacatta agcataacgg ctggcgcatg
     5941 gagtttgatg actggtaatg gtgctccgag aacacccaga atatgggtgt caaactgaga
     6001 gaaatcacag gcttcaatag aatagtgccc agagttatgt ggtcgtgggg cgatttcatt
     6061 gacaataacg tcatcatcag tcgcaaacat ttccacacag agagttccag acaagttgag
     6121 ttgttctgcg attcgcactg ccatagcttt agccttgtct gctagacttt cagaaatgcg
     6181 ggctggtacg atggtcttag acaggatatt gttgcggtgg atattttcct gaactgggaa
     6241 aaacgtcacc tccttgccat ttcctgacac gatgacagaa atctcaaggt caaagttgac
     6301 aaattcttcc aagacgcagt ctgctgagtc tgctagcgca taggctgctt ccaagtctgc
     6361 ttctgaacga ataacctttt gtccatgacc atcgtagcca ccagtcgcag tcttgaggac
     6421 atagtttttc gacaagtcga tatctgccaa gtctaggcta gaagtcacga ccttgtaggg
     6481 tgccacagtg acttgagcct tgtttgacaa aaagtccttt tcaaaaatac gattttgcga
     6541 aatgcggagc agatctgttc cttgagggag ttgtccatcc ttgataacgg catccaaacc
     6601 gtcagcgtcg acattttcaa actcgtaagt gaggacatcg caacggtctg ccaactgacg
     6661 gagggcgtcc acatcgttat aaggtgccac aatgatttcc gccacgcgag aggccgggca
     6721 atccgccgca ggatccagcg cgataacctt gtggcccatg tagatagcag aagtggccat
     6781 catctgaccc agttgaccgc caccgataat tccgattgtt ttagatgagc tcatttgacg
     6841 actcctctgc gatttttcct tgttcttcag caaagttggc aagtgcatcc gcaatggact
     6901 tatcttctac agagaggaga cggagggcaa agagagctgc gttagtcgct ccagcttcac
     6961 cgatagccat ggtcgcaaca ggcaccccac ccggcatctg aacgatagaa tagagtgaat
     7021 ccactccact aagagcacga gacttgactg gcacaccaat gactggaagg gttgttttgg
     7081 cagctaccat gcctggcaaa tgcgctgcgc caccagcacc tgcgatgatg atcttgatgc
     7141 cacgactacg ggcttcttct gcatgtttga acatgaggtc tggtgtacgg tgtgcggaaa
     7201 caactttctt ttcgtaggct acaccgaagc ggtctaggac ttctgctgtt ttttgcatgg
     7261 ttgcccagtc ggattttgag cccatgatga tggaaattac tggtttcatt tcttctcctt
     7321 tttcctcttt ttcaacaatc accttagctt gtgagggacg gcagcagcca ccaaaggtgt
     7381 ctcatgccta aattggaaac ccaaggtctt ccaatttccc tgaacgattg gattatcatc
     7441 caatcgttct ttcacaacgg cggtgattgt tctatattag ctcgctaacg ctcgcaaacc
     7501 atacgatcat taacgtattt tgtgaatttt tatttttctt tttgataatg atcttaggtg
     7561 atggaggcgg aagcaaacct tcggtttcat tcctaaactt tgagcctaag gtctccaagt
     7621 ttccccctga ccagaacatt cactgttctg gtcttttcac cacgacgacc attatcgtgt
     7681 ttggcgacta cggcgcgtta ttcttatatc tttacttaat tgccttgctt ccgatatctg
     7741 ttcggtagaa gagtccttct attttttgtt gggatagttc ttggtagatg ctggcttggg
     7801 cttctttgac ggtatctgct gtggtaacga gcatataaac tcgtccgcca tttgagagca
     7861 gtgctctgct attttccgca aacttagccc ctgcatagta ggtgatgaca tcgccttctg
     7921 tcttggctgg caactcaacg cccctttcat agtctagcgg gtagcccttg gatgcgacaa
     7981 ccacacccag agtcacaccc ttgtccgtcc acatgatatt tggctccttg ctatccagga
     8041 tatctgtgat attttgagca aagtcagagg tcaagcgagg caagataatc tgagtttctg
     8101 gatctccgaa ccgagcgttg aactcaatga ctttcggtcc atcagctgtc aggataagcc
     8161 ctgcgtaaag aactcccaga taaggacgac cttctttaat caccccttct agaactggct
     8221 tgacaatggt gtcaaccgct gtatcaacta cactctgtgg taagtgtgga actggcgcat
     8281 aggcacccat accacccgtg ttaggccctt tgtcgccatc ataggcacgt ttgtggtcct
     8341 gagccgttgg catgatgtag aacttatcac cattgacaaa ggcaaagagt gaaaattcct
     8401 ctccttcaag gaattcctca ataaccacgc gcgcacctga gtcaccaaat ttattgtcca
     8461 aaagcatctc atgagcggct tcgaccgctt gctcaaccgt ctcagcaacg acgacaccct
     8521 tcccaagtgc caagccatcc gccttgacta cgataggcgc accatgcttt tcgatatagg
     8581 ccttggcttc ctcgaaatct gaaaatgtgc catatattgc tgtcggaacg ccgtatttga
     8641 ccatgatttc cttggcgaaa tccttggacc actccagctc cgctgcagcc ctagtcggac
     8701 caaaggcctt aagtccagct tggttaaaat catccacgat gccagcagca agggcatcat
     8761 ctggaccgat aaaggtccaa gcaacatcat tggtctttgc gaagtcaatc aatttagaat
     8821 gttcggaaat agagatattt accaattcca aaccatccag agtcatccca tcattcccag
     8881 gagctacaaa gactttttcc acgtcttttg attcaagtaa ctttttagca atcgcatgct
     8941 cacgaccacc agaaccgaca acaagcagtt tcattcctca acctcttttg cgaattattt
     9001 accaacatta tatcaaaaaa gttcgtttta atcttgtttc agttagcatt ttaagccaaa
     9061 aaaggaaaga aactgttttc ttccctttta tcttcttaat gtctaaaatg tctcacacct
     9121 gtaaagacca tagtcaagcc gtatttatcc gctgcttcga tggattcttg gtcacggaca
     9181 gagccaccgg gctggatgat ggccttaatt cctgctttgg cgatttcttc cacgttatcc
     9241 gcaaatggga agaaggcatc tgaagcaagg accgccccgt ccagacgatc tttggcttgg
     9301 tcaatggcaa ggcgaacaga agccacacgg ttggtttgac ctggaccaac accaagtgtc
     9361 atgtggtcgt tggtcacgat aataccattt gatttgacgt acttgatagc cttccaagcg
     9421 aactcaagag cagtcgcttc tgtctcagtt ggctgacgtt tagtcaccac ttgccagtca
     9481 gctgggcttt ccttgaccac gtcttgattt tgcacgagaa gtccaccgac tacacctgtg
     9541 tattctgctt ccacttcgct agcctcttga gcattaaatg gcaaggcaag gatacgcaag
     9601 tttttctttt tattgatcaa aatggctagc gcttcatccg tatagcttgg tgcaatgatg
     9661 atttcgagga aaacgccgtg catcttctca gctgtcgcag catccacctc acggttgagg
     9721 acgacaatcc caccaaagat agatactggg tcagactcat aagcgtagtc ccaagcagtc
     9781 tcgatgtcat cagcttgacc aattccacat ggattcatgt gtttgagagc cacaacggtt
     9841 ggactatctt tgaagtcacg gatgatacgg atagcagcat ctgcatcacg gatattatta
     9901 aatgacaatt ctttcccgtt gagctgtttg gctgaagcaa tagagtaatc tgtaggcaaa
     9961 gctttctggt aaaagtccgc gtcttgttga ggattctcac cgtaacgcat tggttgcttg
    10021 aggtcataag tcaaagtgag tttttcaggc ttgctttcac ccacttgagc tgtgaagtat
    10081 tctgcaatca aggcgtcata agccgctgtg tgacgaaata ctttggctgc taaacgttgg
    10141 cgagtttcat aagaggtttc gccgtttgct gccaattcgt ccaaaaccac agcgtagtca
    10201 gcaggatcta ccacaactgt aacactggca tgatttttcg ctgctgaacg aagcatagac
    10261 ggcccaccaa tatcgatatt ttcaactgca tcagcataag tcacatctgg tttaaggata
    10321 gtttccttaa atgggtaaag gttgaccacc acaaggtcaa tgagctcaat cttgttgtcc
    10381 ttagccgctt ccaagtggct atccaagtca cgacgagcga gaagccctcc gtggatattt
    10441 gggtggaggg tcttcacacg accgtccatc atttctggga aaccagtcac atcatcgata
    10501 gcaatggtat ccaccccagc attatcaagg gcaaccttag ttccacctgt tgagataatc
    10561 tcccaaccaa gttttttgag ttcttgggca aattcaacaa tgcccgcttt gtctgagacg
    10621 ctgattaaga cgcgtttagt cattatattc tcctttttaa tcattagtta aacaccaatt
    10681 aaatgcagta acagtaaaac aagataagca aaaccaaggc taagcatacc taagatattg
    10741 atccattttc tagtctgtga tttgaacact cttataaaaa tttgataaat cagtaagcct
    10801 acacagacac ctagcgtatt taaagtcaaa tccgttatat ctgttatacc tattgctaaa
    10861 atatactgta agcactcaaa caataaacta atcaagaaac ctgtcccgac tattcttaaa
    10921 ctagataaat tagtttttat caaagggaaa caaacaccta atggaataaa ggaaatcaga
    10981 ttaaataata tttcagcaaa aacaattttt ccatcgacta ttagtggttc tgaaaatgga
    11041 atccaattga tataccttgg agctaagaaa aatgctataa attcaggatt tgtttcaaac
    11101 ttaaataaga ttccccaagt taataacatc agatagacat aaaatacata tcgagttgtt
    11161 tttttagatt ctaacattac aaatacctcc gtttgaagcc gtcttcaaca aacactgact
    11221 ccaatttaaa atcaaagata tcatatgaat catcaaaaag tcaatctgta aatagagcct
    11281 tcactacttc cggatacaac ctgtactctg cttcatggat gcgagcttca aatctgtcaa
    11341 tggtatcatc agctagtcgt ggcacacgaa cctgtttgat gacctggcct gtatccacac
    11401 ccgaatccac ccagtgaatg gtcacaccag actgacccac gccagcattc caagcatcct
    11461 caatcccatg agctcctgga aattctggca agtaggctgg atgaatgttg acaatccgac
    11521 cttcataagc cgacaataag gttggtccaa cgattttcat gtagcctgct aggcaaacca
    11581 agtcaatctg gtgttcttcc aagagttcga caagggctgc ttcgtagtct gccttgctct
    11641 caaactcctt gagttcaaaa gcataggaca gaacgccgag ctgctttgca cgctcaagca
    11701 cataggcatc acgatggtct gaaaagacaa actccactgg aaattcttcg gcaatcacct
    11761 gaaaatttga gccattacca gaggcaaaaa ccgctatttt tttcatttga taatgacact
    11821 ttcgttttct ttcttgacga tgcgaccaat ttcatagact gcttcatcca acaattcttt
    11881 tacacgctct acattttcag ggctgaccgc caacataagt cccacaccca tattgaagat
    11941 ttcaaacatt tcttcgtgtt taatctgacc atatttttca agggctttga aaattggaag
    12001 cactggaact ttgctttcat caatttcagc agctaggtca tctgcaaaca tacgagggac
    12061 attttcgata aagccaccac ctgtgatgtg ggcaatgccg ttgaccaact cttctttgat
    12121 gagcggcaag acagccttga catagatacg agtcggctca agtagaactt ccttaagttt
    12181 cttgccttcc aattctggta ggacttcctc acctgtgtaa tccgcaaaga cacgacgaac
    12241 caaagagtaa ccatttgagt gaagcccact tgaagcaagt ccgagaagaa cgtctccctc
    12301 taccaccttt gaaccgtcaa tgatttgaga tttttcagcc acaccgaccg caaaaccagc
    12361 caagtcatag tcgtcttcgc cgtacatgcc cggcatttca gccgtttccc caccgatgag
    12421 ggcagcacca gcctgcacac aaccttctgc cacaccagca accacttgtt ctagcttagc
    12481 tggctcattc ttccctgtcg ctacgtagtc gagaaaatag aggggttccg cacctgcagc
    12541 aatgatgtcg ttgacacaca tggccacaca gtcctgcccg atggtatcgt gcttgtcgta
    12601 cttgatagcc aacatgagct tggttccgac accgtcagtc cctgaaatca agacgggttc
    12661 tttaacccca gtcttggaaa ggtcaaacat accaccaaag ccaccaagag ctcccatgac
    12721 acctgcacgc tccgtacggg ccacgtgctt tttaatccgt tcaacaactt cataacccgc
    12781 ttcaacatcc acacccgact gggcatatgc atttttattt gtcatttgtt ttttcctttt
    12841 ctttaatgga gaatctgtcg cctacttgta aaaactggtc ttttcttcca aacttctacg
    12901 atagtcttct tcgtagtcat agagaggcgt tgggtagtca ccgtcaaagt aagcgacaca
    12961 gagaccaccg ttcggcgcat ctgtttcgat accaatcgac tcaatcaagc catcaattga
    13021 aagataagtc agactgtccg caccaatgat ttggcgagtt tcttcgaccg tatgattggc
    13081 tgcaatcagc tcctgacggg tctggatatc aatcccgtag aaacatggat acgctagtgc
    13141 aggacttcca atggcaacgt gaacctcagt cgcacccgct tctttcaaga gctgaacgat
    13201 acgacgagag gttgttccac gtacaatgga atcatccacc atgaccacac gtttgccttt
    13261 gacaacaccc gaaacagcag acagtttcat ccgcactcct tgctcccgca attcttgagt
    13321 cggttggata aaagttcgct gggtgtattg gtttttgatc agacccattt catttggtaa
    13381 gcctgattct tccgcaaatc ccatagccgc gcttagggaa gaattgggca caccaactac
    13441 aatatctgcc tcatgcttaa attctcgcgc caattgcgct cccattctct tacgtgccgt
    13501 atggacattg acaccgtgga tattagaatc agggcgagca aagtagatat actccataga
    13561 acaaatcgcc aactgagtat catctgtata gctgtcatac tgaatgccct cgtcatcaat
    13621 gatcacaatc tcacctggct tcaaatcacg aatccactcg gcaccaatga cctcaaaagc
    13681 acaggtttca gaggaaacaa ccaccgctcc gttggccatt ttcccgatag aaagcggacg
    13741 aaagccatta gggtcaagag ccgcaatcaa cttgtcctca aacagcaaga tataggcaaa
    13801 accacctttg acaaggctga gcgcttcctt gattttaccc atcaggctag gattatgact
    13861 gcgacgaatg aggtgagcca agatttcaga gtccgaagtc gcgctgaaaa ttgctcctct
    13921 ttgttccagt tctttcttga gagaggctgc attggtcaga tttccattat gagccaagcc
    13981 aaactgcata tcgtgaaaac ggaagaggaa gggctggatg ttatcaacag aagcttcgcc
    14041 agcagtcgca taacgcacat gcccaatcgc accagctcct gtcaatttat ccaaattggc
    14101 tggatttctg aaaacttctg ataaaagccc catgtcacga tggcgcttca gttgtccttg
    14161 atcattggag aggattcctg ccccctcctg accacggtgt tgaagactgt ggagtccaaa
    14221 ataggtcaac ttagcagcat ctggatgtcc ccaaataccg aaaacaccac attcttcatt
    14281 aagagatttt acttcgtatg tcatttttta tacctaattt tcatttgtaa tcatcaagag
    14341 ctagatttac atgactttta cattactgat actatctatt agaaaatctg taagtcttat
    14401 tttccagtga aatgtttaac cgctgatgcg aacaggtgtt ggtctttatt gcctgggata
    14461 ttttggaaaa gaccatcctc ataacgttct gagtggccca tcttaccgat gatttgacca
    14521 ttcttgctgg taattccttc gatggcatgg acagaaccat tcggattgta cttagaatcc
    14581 atacttggtt taccgttaaa gtcaacgtat tggctgaaaa tttgtccatt gtcacggagc
    14641 tctgcaaatt cctcagccgt cacgacaaac ttcccttcac cgtgcgaaac aggaatagcg
    14701 tggatatcgc ccacttgcac accagccaac catggtgagt tggtattggc aatacgagtt
    14761 tccaccatct tggccacgtg ttggttggca tcattgtaga agagggttgg actagtactg
    14821 ttagcatctt caaagtttcc gtatggtagg agacccgatt tgactaaggc ttggaatcca
    14881 ttacaaatac cgataatcaa gccaccacgg gcgataaagc tatcaatagc cacacgcact
    14941 ttttcattaa gcaggatatt gacgataaac ttagctgaac catctggttc atccgcagcc
    15001 gagaatccac cggcaaagaa gagaatatta gtcttgtcga tattgtcaac catagtttca
    15061 actgacttga caatagcttc ttcattcaag gtcacgaatg gcaccaaatt gacctctgca
    15121 ccttcttttt cgaaggcctt agctgaatca tattctgagt tggttcctgg aaagactggg
    15181 atgtaaacca caggtttttc aaccttttct ttggctttaa tcacaacatc tgataccaca
    15241 gctggtactt cttctagttc tttcgcttgg gtaaattctg ttgggtaaac ttcttccaat
    15301 gtcccttgaa atgcactgtc aagcttgtgt ccatctagct tcacaccgtt gacagtcagt
    15361 gtaaagtctg ctttcgtttg tccaatcttc tctactccag caatttcttc aggagatgtg
    15421 aagacaaagc cgcctaattg agctgtcaaa gctgttttaa gttcaggcaa ggtcacctct
    15481 gcaccaatat agtttccaaa ggtagcaaga gccaaacttt caactacacc accgtatttg
    15541 acagctgatg cagatgtcac tttatggtca gcttggcttg cttcaaactg agcaaaattt
    15601 ttcttaatca agtcaaaatc aatctctgca gagagggctt gacctgggat gtagtagata
    15661 ttttccccaa cagctttaaa ttctggagag agcaccttac ggctatctgc cgtcgtcacc
    15721 ccaaaggcaa ccaaggttgg cggaacggtc aattcttcaa aggtaccaga catggagtcc
    15781 ttaccaccga tagatggcaa gccaagctga atttgtgctt caatagagcc tagaagggcg
    15841 gctactggct gaccaaaacg ctctgcttgc ttgtccatcc gctcgaaata ttcttggtaa
    15901 gagaaacgag ccttagacca gttggcacca gcagccacca aacgagcagt tgcttcgata
    15961 accgcataag cagcaccgtg gtatggagac cattcagcta catatgggtt gaaaccttga
    16021 gcaatgaccg acgcagtatg agtcacaccg tgttgaactg gcaatttctg cacagatgcc
    16081 tcagttggtg tgagttggta acgaccacca agtgggtgat taaccgttga gcgtccaaca
    16141 gagcagtcaa agatagtctg taatcctttt tgacttgcat ggttgaggtc agatagaacc
    16201 gtaagggtat ctgattccag tgtttcagca gatgtttgac gctcttctgg gagtttgaca
    16261 tccttgtcca caactttggc atcgacaacc acgcgcacac cattggtgtc aaggaaacga
    16321 cgctccaagt caacgattgt ctcaccattc cagtgcatga caagatttgg tttttcagtt
    16381 actgtcgcca ccacaacagc atcaatattt tctttgttac attcggcaac gaaggtatcc
    16441 acatcttcag gacgaaccac gaccgccatc cgttcttgtg attcagagat ggcaatttct
    16501 gtaccattca agccctggta tttaagaggc accttgttga ggtcgatttc aagaccgtct
    16561 gccaattcac cgatagccac acagacaccg cctgccccaa agtcattgga cttcttgatc
    16621 agacgagtga cattgccatt acggaagagg cgctgaatct tgcgttcttc gatggcattt
    16681 cctttttgaa cctcagcacc agcagtctct acagactcaa ctgtttgaac cttagaagag
    16741 cccgtcgcac caccgacacc atcacgacct gttttacctc cgagaaggat gatcacatca
    16801 cctgcttcag gtttttcacg gacaacattg cccttgggag ccgcaccaac aacggcacca
    16861 agttccatac gtttagctac aaagcctggg tggaagtatt cacgaacgta ggttgtggca
    16921 agcccaatct ggttaccata tgaagaataa ccatgagctg ctgttttaga aatgacttgt
    16981 tgtggcaatt tcccagcgcg agtttccgaa atcggtgctg taatatcacc agcacctgaa
    17041 atacgcatgg cttggtaaac ataggaacgg cctgacaacg gatcacgaat agctccacca
    17101 atacaggtag ccgctccacc aaatggctca atttctgttg gatggttgtg ggtttcgttt
    17161 ttaaacatga ggagccaagg ttccttgaca ccatcaacgt ccacttcaat ttcaactgag
    17221 caggcattga tttcgtcaga gacttccata tcatccaatc gtccattagc acgctcataa
    17281 cgaccgaaaa tagtcgccat atccatcaag gtttgtggtt tttcagaccg acctaattcc
    17341 tcgcgcatgg caatatactt gtcataggtt gactgcaatt gcttttgaaa tttagaagct
    17401 gaaaagtcga tgtgtttcaa ctctgtctca aaagtcgtat gacggcagtg gtcagaccag
    17461 taagtgtcca aaaccttaag ttcagtctca gttggcacgc gcccgattga cttaaagtag
    17521 tcttggataa agagcaaatc atccacttcc atggccatcc cttgttcggc cttgtagcga
    17581 gcaaaatctt ctgctgtata gctttcaaag aaagtcaatt ttggaatggt cttgtctgac
    17641 tctgaaaact cctgcttggc aatccctgtc gtgatatcct tgaaacgaga atcaactgga
    17701 ttgagcaggt agtttttgac agctttcaac tcagtcgcat caatatcttt attcaccaag
    17761 taaagttggg ctgtgttgac tgtcacgtca ctcgaacttc ccaacaaaag caaggcttcc
    17821 tgtgacgaag ctgcacgctg gtcaaactgc cctggtagac tttcaatggc aaagaaagca
    17881 tagttagcaa gatccgcctg cacagatact tcatctaaaa catggtcggt tacctgctca
    17941 gagaaaatgt gcttctctgc aggtgcaaac aagtcctcaa ccaagtcaaa tacatcatat
    18001 acttgcacaa tacgaatact tttcaagctt gacagtccca agttgtgctg gagctctcta
    18061 accaaactct ctgacttgac ctgaaaatca gccttttttt caacaaaaat acgtttatcc
    18121 atcaattctt attcctttat ttcagctctt gcaatattcc caaacagcct tgaggttgtt
    18181 attttaaacc ctgcaacttt tcccaaacaa tctcataaac gtcggttagt tctcccaatc
    18241 ctctacggaa aacatcctta tccatgtggt tgccatcagc gtcccacaag cggcagttat
    18301 ctggtgaaaa ttcgtctgcc aagataatct tgccatcctt gtcaaaaccg aactctagct
    18361 taaagtcaat caatttaagc ccaatctcag caaaccagac tttcaatagt tcattgatac
    18421 gacgcgtttc ttccttcaag taggcaatct gctggtcacc cgcaatctgt aggaatttca
    18481 catgctcatc attgataaat ggatcatcca aatcatcatt tttgtagtaa aattcgacaa
    18541 tcggagtctc caaggcgatt ccctcatcca caccaaaacg ttttgaaaag gaaccagcag
    18601 tatagttgcg gagcacgact tccaaaggaa taatcttaac ctttttattg agttgttccg
    18661 tgtctgaaag tttctccaca aagtgagtcg ccacaccagc cacatttaat ttctcaaaaa
    18721 taaaagatga gatctgatta ttcaagactc ccttacctgc aatctgctcc ttcttgacac
    18781 cgttgaaagc agtcgcctgg tccttgtaag ttgaaataat aagattttca tcctcagttg
    18841 tatagatatc tttagctttt cccgaataga tcaattgttt tgacatttta aagttcgcct
    18901 ttcgtattac ttgagcacat tttaccacaa aaaaccaaaa aacacaagaa tttaaccgaa
    18961 taaatagtag atgtttttca aaaattgtaa agaaaaaact gcaagaagaa tctttctcac
    19021 agtttaaaaa ttatttaact ctaaaaacac gaacattact ctttgttcaa aaattgatcc
    19081 aaataataac gtaggtaact tttcttgccc gtaatcatct gcaagcggcc ttccaccccg
    19141 tacctaagtt tttcagcctg ctccgaagtt agattagtct ccgcctcgat tttaaagaaa
    19201 ttccctttct cagtcttagt agctgtcgca tcaatacttg taatagtaga atctaggaaa
    19261 agttgattcc cggcatcatg agtcgtagta tagcgaacag aatcaccgac cttgattctt
    19321 gctacatatt ttgaacttag ataagctgtg agtttggctt tcccttctct ttccaaagat
    19381 ggataaagtt gggctagtag ggcaccttct gcaaccatgc tagaatcact ggtctcagga
    19441 ttaagatgaa gcaccccatc ctcactcgcc gtaactttcc ccttgtctaa aagatttccc
    19501 tgtaccttct tacctgactc tgcctccaaa attttctggg ctagaagggt caattcctga
    19561 ccaacctttg ccaagtgttg ggatttaagg gattccaatt gactgcttaa ccctgacgca
    19621 taggcttgct gggtacctga acctgcatac tggacacggt aagtagcaag actagattct
    19681 aactgagaaa tctgtgcttc aacctgtgca actgcctgaa ccttagtttg gggattttcc
    19741 tcgccctgag acttgtagga ctggtaaaga gagtaggcta gattctgacc ggccaaggaa
    19801 gcacctgttt caatagctga cttagctgtc tggtaatcgc gaattttagc ctctgtttga
    19861 ctgatgaggt tgccgatttc ggcttgggtt tggctagctg ctgcattctg ggacgcgatg
    19921 gtctcatttt gttgcgatgt actagcccta agactgcctg cttgactgat gtagtcgcga
    19981 aaggtggctt ggtagccaaa cttatcctcc tctggaaagt ggttctcccc ttcttgcagg
    20041 ctcttttgca gatactccaa ttgctttttt tgatccttta gcatgtccaa ctgactggca
    20101 taggactccg cttggacacc ctctgcccct tcttggtatt gaaccaaaag atcccccttc
    20161 ttaaccagct tattttcttc caaatgattg acaagaatac gattgttgct agttgactgg
    20221 atatttgcaa ggatacgact aggttcgaca gtagctctag tggacaaact catctccttc
    20281 tctgcaacag ttgcaaagcc aagtaaaaac acaagcagaa gggccatggg tacaatcaca
    20341 ctactggaaa aattatggta acgacgatta taaaactccg cactttctaa aaattctggt
    20401 ttcatcctct cctctttcta gctattgacc aaatgggcgt aaaagccacc ctgtgcaagc
    20461 aaatcagcat gctttccttc ttcgacaatc ttgccctgat ccaagacaac taccttctct
    20521 gtccgctcag caatagtcaa gcggtgagca atgaaaatca aggtcttgtc caaagccatg
    20581 agattatcga caatccgctt ctctgtcaaa atatccaaac tgctagtcgc ctcatccaaa
    20641 atcaagaccg gcgcatctgt caagagagca cgcgccaaag cgattctctg acgttgacca
    20701 cctgaaatcc ctgccccatc cgaagtcaat tctgtctggt aattcagtgg catgcgctcg
    20761 atatcctctc gaatctctgc caattcgacc gcccgtaaga tatcttcctg tgtcgtcccc
    20821 tccttggctc ccaaaagaag attctccaaa atcgttccgt taaagacata gggctgttga
    20881 ggcagatagt tgatgtactg gcgcagggct tttttatcaa tctgattgag attgacacca
    20941 cccagactaa tctccccttg acttgggtcg taaaaattaa ccatcatctt ggccaaagtc
    21001 gtcttacctg accctgaaat ccccacaaaa gccaccttag acccttgggg aacggttaaa
    21061 ttgatatccg acaagacgtc tcgaccatag ccatacttgt aatgaacctg cttgaaggtc
    21121 atatctccct tcatcaagct caaatcctca actgttttct tctcctcaaa ctcagaagct
    21181 actagataca cttcatttag acggttattg gcaacctgcg ctgtctgaag cttggtttgc
    21241 agattgatga tattttccaa aggattggta aagtaaacca gcaaggtatt ataggtaatc
    21301 aactgcccca aactcatctt gccatccatg accagaacag cccccatcca gagaatgccg
    21361 acattaagca agagatgggc aacctttttc agagcctttt gctgactctc tgctcgacta
    21421 taggtaaagg atttcttcag ataatccaca aattccttgt caattttttg gtaacgctga
    21481 ctttcactgg tcaaggactt gatagtctca ataccgttga tgtcctcaat gatagaagaa
    21541 gacagaaccg cattggcttc catggtatcc cgattcatct tttcaaacgg cttcataaag
    21601 gcaaagataa tcactgtgta gataggaagc gccaataaag tcatgaaaaa gagattggta
    21661 ttttgtgaaa atagaacaag ggaaataatg acaaccgttg acacatctag gaaaatcgaa
    21721 aggatggtcg aagccagcgc atcgatgata ctgttagcat ctgtaaaacg agacacgatc
    21781 tcccctgtcc tgcgtgtcgc aaagaaggac atagggaggt gaaaaacatg cttgatatag
    21841 gacaaaatca cgtcaatcga caagcgttgc cccaaaacaa gcaagagata ctcctgagcg
    21901 taagacaaga tttgctggag gatgtagacg atgactagcc caatagaaat aatccctagt
    21961 gtcgaacgca tctgatctgg cacataggta tcaatgatag actgcagata ataagaaccc
    22021 acaatgttaa tcacggttac caagagtgtt gccaaaacga tattggcaat caagccacgc
    22081 tgcttcacta atatagggat aaaagagagc agaccatttt tttgttcctt atgaggctta
    22141 tagtctggac taggtgccat aaaaagagtc actcctgtcc attcttcctc aaaacgctca
    22201 cgtggcagtt tagtcaactt caccccggga tctggatcgg caatatgaat gctatcctta
    22261 tcctgcccag tcaccacata gtagtggagc aatttccctt ccttaagcac atgggcaaca
    22321 aaaggaaaag tcaaatccgg caagtcaaaa agcgtcatat ccgccttaat ggctcgcgtc
    22381 tcaaaaccaa tctcctctgc caccttgacc aagcccaaag ccgtcgtccc atccatggtc
    22441 gtcttagcca attctcgcaa gtgagccaaa aaataataac taccatagta gccaaaaacc
    22501 atggctaatg aagctacacc gcagtccatc tgatccactt gcggacgata gtgacgtttc
    22561 ccaaatttca tattcatctc cttttcccta atactcaatg aaaatcaaag agcaaactag
    22621 gaaactagcc gcaggctgct caaaacactg ttttgaggtt gtagatagga ctgacgaagt
    22681 cagtcacata tatacggcaa ggcgacgttg acgtggtttg aatttgattt tcgaagagta
    22741 taaactcatc tgataacaac tatcttaccc caatcactaa acaaaaactg gacttccttc
    22801 ccaaatgcgc ctatctccct cccaactgca ctttttggat aaaaaaatag gcagaacaag
    22861 agtcctgccc actaaaaata tgctattgaa aggaaattga ttttttactg tcaccctagg
    22921 caagcttgaa acaaataaat cattgatagt aacacttacg acatcctatt tattacttca
    22981 atttctaatg tctctgctat ttctaagcta cctctggtat gatctattcc tagtcagaat
    23041 agataacacc gttctaaatt acgattcata gttactcctt ttttgactcg ttactataag
    23101 actcctcttt acatgcgcaa aataattttg attcagattc atcatttata gttttgatta
    23161 ttttttaaca gatttttctg ttttcttctc cgaagacttt aaaaattttt ttctaattaa
    23221 atcatccata taaggaccaa atataccaac tactaaacca ataataaaac ttttaaaatc
    23281 cataattacc accaacatgt cgctgcatag gccacacctc caagtatagc tcctcccgca
    23341 gcaccagttg ctgcaccttg ccatgttctt gttttaattc ctagctgaag acctcgtgct
    23401 gctcctcctc caacacctgc tttggcaaaa tctccccaat tgcatccgcc accttcaacg
    23461 caagcaagca tctcagtatc cataatttca aattgtgaca tcttttttgt attcataacg
    23521 aatacctctt ttttattttt aatatttgtc ttgttacaaa cttgacaagt ttagtataac
    23581 agtatctatt aatttttttc atccaaatct tgaattggca tcgaaacgtc ttgaattagc
    23641 ttttttgttt caaaatcatc tctattttta aaaaagatgt tttctaatca cttttttact
    23701 attagacttc ctgcaaaact agaatcctag ttcatgattg ataataccag caatcaaatt
    23761 cattcgtaat ccgaagcgtt tacgatgatt tcgataggtt gttgaaaaca ttttaaacgt
    23821 ttttactttg gcaaagatat tctcaacctt gcttatctcc ttagatagcg catgattaca
    23881 ggctttatct tcaactgtta gcggcttgag tctgctggat ttacgtggag tttgtgcttg
    23941 aggatatatc ttcatgagcc cttgataacc actgtcagcc aagattttac cagcttgtcc
    24001 gatatttctc atttctaaaa accatctact tccgttgact tggaactccg attgctattt
    24061 tccttgaatg attttaacca catctcctac gttttggagt tggtcaattt cttcatcgct
    24121 gatttcgata ctaaattcat cttccagagt caagataaac tccatcaagt caacagaatc
    24181 cgcatccaaa tcgtctttca gactcaagga ttctgtcacg acaaagtcct ctccctgtcg
    24241 ctcttggata atggtcacaa tacggtcaaa aatttctttt tctgtcatct cttttattct
    24301 cctgaaaatt cacgcgcagt ctgggcaacc acgtctgttt ctagcatggt acggatctga
    24361 cgaatcgtac tataaacagc cttggcatcg cttgagccat gagtcttgac aacaggtgcc
    24421 ttaacaccaa acaagaccgc tccaccaaca tctgaataat tgagctgttt tttcaaacct
    24481 ctgaggctgt ccttgagaag gagggcacct agtttcgctc gaagaccacc acctgtaata
    24541 gctgtcttga gcaagcccat gattcccata gctgtccctt cgatggattt gagcacagcg
    24601 tttcccgtga aaccatctgc cacaacaaca tctgcaacgc cattcatcaa atcacgcgct
    24661 tccacgtttc cgataaagtt caaactttca tcagccgcca gtaattcata agtttcctta
    24721 cgaagcgggt cgcccttgct actctctgtt ccgttgttaa gcaagccaac gcgtggttgc
    24781 gcaatgccac gaacattctt ggcatagaaa gaacctagga cagcgtattg atggaggtgc
    24841 tgggctgtat tttctgcatt agcaccgagg tcaagcatgt caaaaccttt cccatctaca
    24901 gtcggcaatg ttgacataag tccaggacgg tcgatattct tgatacgacc cacgatgaag
    24961 aatccagcag ccaacaaagc acctgtattc ccagccgaaa ggacagcgtc tgcttcacca
    25021 tctttgacag ccttggctgc caataccata ctggcatttt tcttattccg aatagctctc
    25081 gtaggttcat catccgaatc aatcttctca tccgtatgga taatgctgac gcgctctgtc
    25141 gctgtcagat attgcttgat tttagcttca tctccgtaga gttgaacctc gatatctgaa
    25201 aagtcagata gggcttgatt gacaccctca acgatggcct gaggtgcgta atcgcccccc
    25261 atggcatcta ctgcgatttt tttcatttct tttcctcttt tagtaattgt ccccagtctg
    25321 ctagggaatc aataaatttc tttgatttta ggtgaatccc aacgtactct tcatatagtt
    25381 gatccataaa ttggcgtagc tcttgcttga ttccaggctt gagcgaaatg gtctccaaag
    25441 tctcaaaatc aatagcttga aattgattga gcagataggg gatattggga ttgagatggc
    25501 aacgtctctc atcctcatga taatgctctg gacagagaca ggttccatat ttgaaagaaa
    25561 agtcaaaagc ctgaccaacc cgatggcaga agacacactc attaaaattg aggctgattc
    25621 caaatcgagt caaaatttga atttcaaaaa tattggtcaa aacctgataa tccaagcctg
    25681 cttccatcaa ctccaaagtc ttttgcaaaa aagcaaacaa gggagcatcc tgctgattgt
    25741 cctgcaaact agcatctgca agagctgcca cataggtcgc ataggccatg acaaagaggt
    25801 cactattaat cttgggaaaa gtcatgacct catgatagtc ttcgatgtaa ctgagtccgt
    25861 catcattgat tcgcaagaga aatcgtgcca gcaccaaggg ctgaataaca ggcgccagct
    25921 tagactgacc agcgtgtttg acaaaaaaca tgcgtttgcc aacctgctct gtaaaaattt
    25981 tgacgagctt gtcatcctca cgaaaattgc gattgtaaag caccaagcct tgactcgtga
    26041 tagactgaat catgcttctc tcatgtactc ctcaagtcgt ttcatggctt ctttgatagt
    26101 ctccatgctg gctgcataag ataggcggac gtagcattcc ccgtaacgtc caaaggctgc
    26161 accagggata aaggcaacgg ccttcttctg agcaaaatcc ttcagaaaag caaaggagtc
    26221 ttgattgtag cccgctggaa ttttagcaaa aatatagaag gcaccgtctg gtttgataat
    26281 ctcaaaacca agagcagtca ttttttcgat gatatagtcc cgacgctgga tatattcctt
    26341 cttcatgggc tccgcatcat ttttaccagc cgtcaaggct tctaccgcag catgttgcgc
    26401 catggtattt gcggcagtga ccaagtattg gtgactcttg attaactggg ctgtgaaggc
    26461 cgcaggagcg aaaatcagcc ccaaacgcca acctgtcatg gcatgcgatt tagacaaacc
    26521 attgataata atagcctggt ctctcaacat cgttcctaga gacacatggg cttcgcctgt
    26581 gtaggtcaat tctgagtaaa cctcatcaca gacaacaaaa atttcgtact tgcgtaaaac
    26641 agctgccaag gcctctaact gctctcgact gtaggtaatt cctgtcggat tggctggata
    26701 gttgagaata accgccttga gcttatcacc ctgctccaaa atggccttct ccaacatctc
    26761 aggagtcaag acaaaaccat tttcagtcgt atcaatctca acaatttctg ccccaactag
    26821 attgacaatc ggttcataac ccggataagc aggagctggc aagagcacct tgtctccctc
    26881 ttccaaaata gccgtcaaag tcgcagataa agcctctgtc gctccgatag tgaccaagat
    26941 ttcattttca ggagcatagt ccagttggta cttttcctta acaaaatcac tggccgcctg
    27001 acgtagagtc agcagaccac tcatccctgt atagtaggat tggttctgat caatcgctcg
    27061 cttggccgcc tccttgacat ggtctggcgt tgtaaaatca ggttccccca aggtcaaacg
    27121 caagacccca ggaatctccg aaataacctg gtcaaactga cgaatcaacg aaacttgaat
    27181 tttatctaac tgtttattaa agcgcttagt taagtccata gatacctcct actttcaaaa
    27241 cgtatctcta ttatactaca aaagcccccc gaccgcaaaa atacattaga gaatagcttt
    27301 ccactttcta ttttactttt cctgtttaca ggtctataat ggtaacagat tctatttgga
    27361 ggtttttatg tcatttctat caaaaaatgg agcaggcatc ttggtctgcc ttctcatttc
    27421 tatcgtatct tggtacttag gaggattctt ccctgtgatt ggcgcgcccg tttttgcgat
    27481 ttttatgggc atgctcctac atccctttct ctcgtcttat aaacaactgg atgttggatt
    27541 gacctttagt tccaagaaat tgctccagta tgccgttatc ttgcttggtt ttggtctcaa
    27601 tatctctcaa gtcttcgcag ttgggcaatc ttcactccct gtcatccttt ccaccatttc
    27661 aatagccttg attgttgcct acctcttcca gcgcttcttt gccctggata caaaactggc
    27721 taccttgatt ggagtaggtt cttctatctg tgggggttct gccattgcag cgacagcgcc
    27781 tgttatccat gctaaggaaa aggaagtagc ccaagccatc tccgttatct ttttcttcaa
    27841 tgtcttggct gcgctcatct ttccaaccct cggcacctgg cttcatctat ccaatgacgg
    27901 cttcgccctc tttgcaggaa ctgcggtcaa tgatacttcc tctgtaaccg ccacagctag
    27961 cgcttggaac agtctctacc agaccaatac cctcgaatcc gcaaccattg tcaaactcac
    28021 gcgaacccta gctatcatcc ccatcactct ctttctctcc tactggcaaa gtcgcgagca
    28081 aaaaaataag caaggcttac aactgaaaaa agtcttccca ctttttatcc ttcacttcat
    28141 ccttgcatcg ctcctaacca cccttctgac ctctctcggt gtgtctagta gtttctttac
    28201 ccctctcaaa caactctcta aattcctcat tatcatggcc atgagtgcca tcggtctcaa
    28261 aactaatctg gtcgctatgg tcaaatccag tggaaaatcc attgttctcg gagccgtctg
    28321 ctggattgcc atcatcctca ccagccttgg tatgcagacc cttatcggca ttttctaata
    28381 ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg ccgtatatat gttactgact
    28441 tcgtcagttc tatctgcaac ctcaaaacgg tgttttgagc tgacttcgtc agttctatct
    28501 gcaacctcaa aacggtgttt tgagctgact tcgtcagttc tatctacaac ctcaaaacag
    28561 tgttttgagc agcccgcggc tagtttccta gtttgctctt tgattttcat tgagtataac
    28621 acaaaaggta gcccatcagc tacctttttc ttatgcttcc tcaatcaagc gagtatgttc
    28681 tctcttgata cagcgattca tcacgatatc atcacatcca ccatcacgca aaatctcttt
    28741 cgcttctaaa ctttcaagtc ctagctgtgc ccaaaaaatc ttggcatcag ctttgagaaa
    28801 atcacgcgcc acatcgggca gaaattcact gcgacgataa acattgacaa tatctacagg
    28861 aaaaggaatt tcagcgaggc tagcataagc cttttcaccc aagatttcgc cacctgccgc
    28921 cttgggattg actgggatga ttttatagcc ccgagcctgc atttcctttg ttactcgatt
    28981 gctggttgtt tcttcacggt cagacaaacc caccacagca agggttttac tcgttgcgag
    29041 atactgacga atcacgccat cacttggatt gataaattct tgactcatag aaatcctcct
    29101 ttttcatcag tatagcacat tttgaaaagg tttgcagaat tatactacaa aaaaggagga
    29161 ctagccccct ttttatttag cctcgtacca ggttgcccct tcattctcat ctgcgataag
    29221 aggaacactg agttgaatgg cttcttccat ggtttgtttc accaattttt tcatctctac
    29281 caattcagat ttaggcactt caaggacgat ttcatcgtgc acttgtaaca gcatcttagt
    29341 ctgataacca cctgcaacca aggctttatc cagctgaatc atggcaatct tgagaatatc
    29401 tgctgccgaa ccctggatag gtgagttgat agcagttcgc tccgcaaaac cacgaatatt
    29461 gaagttgcgc gaattgatat ctggcaactc acggcgacgc ttaaagaggg tctctacata
    29521 gcccttatca cgcgcctccc gcaccacttc atccatgtag tttttaatac ctggaaaacg
    29581 ttcaaagtag gtatcaatgt aggctttggc ttccttacga ctaattccca aattattaga
    29641 caagccaaag tctgaaatcc cataaaccac tccaaagtta actgccttgg cattgcgacg
    29701 gtcgtttgca gtcacatcat caggacgctc aatgccaaag acccgcatgg ctgtcgaagt
    29761 atggatatct gccccctctt ggaaggcctt aatcaagtgc tcatccttag aaatatgcgc
    29821 caaaacgcgc aattcaatct gtgaatagtc agagctgagt agcacactat cctcccactc
    29881 tggcacaaaa gccttccgaa tcaagcgccc ctgttccaat cgggcaggaa tattttgcaa
    29941 gtttggatcc acactagaca aacgcccggt ctgggtcaaa tcctgcacat agcgagtatg
    30001 aatctttcca tcagccaaaa tccagtcctg caagccaatt acataagtag attgaatctt
    30061 agcaatttga cggtaatcca ggattttctt aacaatcgga gcaataggag cgagacgctc
    30121 caacacatcc actgctgtcg aataacctgt cttggttttc ttagtgtatt ctagaggaag
    30181 tcccaatttc tcaaagagaa gcacgcccaa ctgcttaggc gagttgacat taaactcctc
    30241 accagccagc tcgtaaatct cttgagtcag tttttcaatg acaagctcat tttcagcctg
    30301 catctcaagc aaggtctctt tcttgaccat aatcccagca atttccatct tggcaaggac
    30361 aaaagccaga ggttgctcca tatcataaag aagctctaat tgcccatttt cgctgagttt
    30421 ttcaagtaaa ataggctctg tttctaccaa aacagcaagt ttacaagcta agtgttccaa
    30481 gaatttctca cgttcaggaa tggccttttt aacaccctta ccgtagaaag tttcatcatc
    30541 aaccaagtaa gtctgaccat aaagactagc gatggtcgca atttcattgt cctccacagt
    30601 cgaaaggagg tatttagcca aacggatgtc aaaagcaggc gcctgcaaat ccacaccaaa
    30661 acgttgcaaa agaactttaa ccttcttaaa gtcataaact ctcagagatg ttttttctaa
    30721 gaaatccttg aaaatcgggt cttgcaacag ctcaagcttg tctgtggcat agagcttatc
    30781 cccacaagac caggcaaatc caaccaaatt atccgtatgg taattctcac caaaaagctc
    30841 aaagtggaag atagactctt cactcagcat atcttgactg atttggtcaa caatagtaaa
    30901 atccaaactc tcagacacat cagctgacga cacatttaaa gcctgcttta gctgtttgaa
    30961 gcccatctca tcgtagaatt tcccaagatt ttcaacatct ggaccactat agaccaagtc
    31021 ctctaaacca atcgcaatcg gtgccttggt atcaatggtc gctagtgttt tagataaaaa
    31081 ggcctgttcc ttgtcattga tgagattttc cttcatctta gaagtcttca ttccatcaat
    31141 attttcataa atcccctcaa gcgaaccatg ctccagcaag agcttaatac ccgtcttttc
    31201 accgactttg gtcaccccag ggatattatc cgacttatca cccatgagcg ccttgagatc
    31261 gataaactga gctggtgtga ggcccatttc ttccatgagg taatctggcg taaaggcctc
    31321 aaactcagcc acacctttct tggaaatttc aaccaccgta tgctcatccg tcagctgaat
    31381 caaatccttg tccccactga caatggtaat atcaaaacca tcctgctctg ctagcttatc
    31441 cagcgtccca atgatgtcat ccgcctcata ctgagccagc tcatagtgac gaatccccat
    31501 atgatccagc aactcacgaa tgaaaggaaa ttgctcacga aactcatcag gagtcttggc
    31561 ccgaccaccc ttatagtccg catacatctc tgtccggaag gtcgtctttc ccgcatcaaa
    31621 agccaccaaa atatgactcg gctcaacccg ctccaacaaa tgactcaaca tcaactgaaa
    31681 accataaatc gcattggtat gcaaaccagc cgcattctta aaacggtcca actgctgata
    31741 cagcgcaaaa aacgcccgaa aagctacaga agacccatca atcaataata attttttctt
    31801 atccatacac ccattataaa ggaaagaatc aaaaaatacc attgggaaga gctagagcaa
    31861 gtatttttca aactttttcc gaataaatag atagagccag agaatttagt aaacctagat
    31921 ttaaaaatgt gctataatat agtatattga atctataata gtacaccttg actgctaaaa
    31981 tatttctata aattaatttg actttcctga tagagttatt cacatcttat ttcaactcac
    32041 tatagaagga ggaataggag gattctcaga catccgggca tcagcccaac taatgatttg
    32101 attgctaaga aaatattcag caatccagaa atcacttgtc aatttattcg cgatatgctg
    32161 gacttgccag caaaaaatgt gaccattttg gagggaagcg atattcacgt attactctcc
    32221 atgccttact cggtgcagga tttttatacc agtatagacg tcttggcgga gttggataac
    32281 ggtactcaag taattattga gattcaagtc catcatcaga attttttcat caatcacttg
    32341 tgggcttacc tgtgcagtca ggttaatcaa aatcttgaaa aaattcgtca gcgagaaggt
    32401 gatactcact agatctacaa acacatcgct cctgtttacg tcattgctat cgtggatagt
    32461 aattatttct cagatgacct ggcttttcat agctttagta tgcgcgaaga cacaacaggt
    32521 gaggtattgg cgattaccaa caatggacag gaaaaccatc tggttaagat ggcattcttg
    32581 gaattaaaaa atacagagaa accagcaaag acaaggttcg caagccatgg ttggagtttt
    32641 tcggcaacaa accctttacc cagcaaccgc aacgagccat tacccaagca aatcaactgc
    32701 tggactacaa gagctggtcc gaggaggaca ggaaaatgtt tagtcaacta catatgcgag
    32761 aagaacaagt cttgttagca caggactatg cctcggaaac tgctagggct gaaggccttg
    32821 aacaaggact agagcgtggg aaagttgaag gaagggcaga aaggaaactt tttgccttcc
    32881 tagacatagt acgccaaggt cttctgactt ctgaggttgc cagccagcaa ttaggtatgt
    32941 cagtatctga atttgaggca ctgttgtaaa atggctccat aatatccata ggggatttac
    33001 ccactatgga tattatggag cctattttgt gtaaaaaaaa aagtcccata tgacctataa
    33061 tgaaaagcga caaaacaact cattagaaag aatcatatgg aacaattaca ttttatcaca
    33121 aaattactag acattaaaga ccctaatgtc cagattttaa acatcatcaa taaggataca
    33181 cacaaggaaa tcatcgccaa actggactac gacgccccat cttgccctga gtgcggaaac
    33241 caattgaaga aatatgactt tcaaaaacct tctaaaattc cttatcttga aacgactggt
    33301 atacctacta gaattctcct tagaaagcgt cgattcaagt gctatcactg ttcaaaaatg
    33361 atggtcgctg aaacttctga tgacgtacag tcatatttct tttcttttta ttatatcaca
    33421 gttttaaatc tagctttact agattcaccg ctactatcta tttattcgga aaaaagacga
    33481 aaaaacctga gaatcatctc aggcttggtc attaaatttt tttctcaata tcgaaaagtg
    33541 gagaaagtgg tcgtttttca tgaatacgta cgatagcatc ccctaggaga tgagcgattg
    33601 aaatctgctc aatcttatca atcaaacgct cttctggcag atagatggta tccaaaacaa
    33661 ccaatttctt aatagctgat ttttggatat tgtccgtagc aggaccagaa agaactgggt
    33721 gcgtacagct tgcatagact tcaacagcac cagcttccgc aagagcatct gccgcatgac
    33781 aaatcgttcc agcggtatca atcatatcat caatcaagat acaagtcttg ccttcaacct
    33841 taccgatgat gttcataact tcactagtat tcatcttatc aacgctgcga cgtttatcaa
    33901 taatagcgat agatgttttc aaaaattctg ccaacttacg agcacgagtc acccctccat
    33961 ggtccgggct gacaaccaca tagtcagaac caaccatacc acgacgctca aaataatctg
    34021 caatcagagg agcacccatc aaatgatcca caggaatatc aaagaatcct tgaatttgcg
    34081 cagcatgcaa gtcgatggtc aataaacgat ccactccagc tacttcaagc atatttgcga
    34141 caagttttga agtgattggc tcacgcgctc tcgcctttct atcctgacgt gcatacccat
    34201 agtaaggcat gacaacattg acagattctg cactcgcacg cttcaaagca tctaccataa
    34261 tcaaaatttc aagcagattg tcatttacag gcgaactagt tgattgtagg ataaagacgt
    34321 gtttcccacg gattgattct tcaatgttga cctgaatctc tccatctgaa aattggcgaa
    34381 cacttgattt ccccaactct atcccaatct cctgcgccac acgttctgcc aattctttat
    34441 tagaagaaag ggcaaacagc tttaaatcag aaaaagacat gatttcctcc ggtatatatg
    34501 tataacttgt gcctttcaca agattttcca tctaccattg tagcgctttt tgcactattt
    34561 ttcaatcaaa aataaaagaa gggcaccata tttgtaccct tgcatcattc ttttgaaaaa
    34621 tattctaggt catcaactca ttgtgtttct caacaaagca ataagcatga taaaaaccat
    34681 agagagcaat agccgtaacc actggaatcg ctaaaggcaa ctctgtttcc aactccacaa
    34741 aaggagagtt aaacaagaag tgagttccca aggctaaacc tagaaaaata aggccctgtt
    34801 tcttgccaac cttctgtcct ttataggctc tgtaaagcaa gtaaacacct actacagcta
    34861 gacctgaaaa agtccagtga gaggcaattc ctgagatgat acgctctaaa attcgcgaaa
    34921 tagtaaagtc aaagccctct ggcaaatccg tacgaatata accaatatcc tcaatcattt
    34981 ggaatcccaa accggaagca attccaagta aaaacaaaga ttttaatttt cgcacaggaa
    35041 tcaaagccaa aacaaaaaca agtggcaata atttcaaggg ttcttctacc aaaggagcca
    35101 caatagcact ttcaaaggca tttaaaaatg tactatctgg gaaaagaacc cccagtaaat
    35161 catggatata agtattagca aaactagaca accagcctga aaggaacatc cctcccaata
    35221 aagacagaat caaaaccttc tttggcaatt cccatttttt cccaatacgg aagagaaaat
    35281 aaagagccgg aatcatgtaa aagagagcta gaaagataga aactcccatt agtccatatt
    35341 ccgcacctga cctcgaaccg tccgtatagt agatggtttc atactgtaaa ccaatacata
    35401 gcaataaaat aaaaataaat aaaatactgc tcttcttcat acactttctt tctaaatgaa
    35461 gtatttataa ttctacgact gtcatacttc ctgtatcaac attgtaaata gcaccagaga
    35521 taatgacatc gtctggtatt aggggagact cgataagcag ttgcatatcc tcgcgtacac
    35581 tctcttctat atcttggaag ggcaagaagt cctggtctga cacatctaca cctaattcct
    35641 cttttaaata ctcctgaaaa ggttcatttt caaaggtctg agcaccacag tctgtatggt
    35701 gcaataccac aatctctctt gtccccattt gttgctggga aataactagc gaacgaatca
    35761 tgtcttcagt cactcgacca cctgcattcc gcaaaatatg agcatcccca agtgccaagc
    35821 ccagagcttg cgcaacgtgc aaacgtgagt ccatacaggt cacaatggct actctggttt
    35881 taggtttaag tggcagattt aactgcccat gtagggcaac ataagcctga ttggcttgca
    35941 taaactgttc aaaatacgac acgattccct ccttgaaaat ttgatagtca aatatttctc
    36001 ctatcttatc atttttaaga gaatttgtca cggattatgc aaagaccttt ttcaaaactt
    36061 cctgaatcgt tgtcacgcca atgacctgaa tttccttagg cagagtgatt cctgtcaagg
    36121 aattctgagg tacataaatc ttagtaaagc ccagtttagc agtttcgttg atgcgttgct
    36181 caatacgatt cacgcgccga atctctcctg tcaagcccag ttctccgaca aaacattcct
    36241 gaggattagt tggcttgtct ttgtagctcg aagcaatagc aactgcaaca gccaagtcaa
    36301 tggcaggttc atccaattta acaccaccag cagatttgag ataggcatcc tgattttgca
    36361 agagaagccc tgcccgtttt tccaaaacag ccataatcaa gctagcacgg ttaaaatcaa
    36421 gtcctgtcgt agtacgcttg gcatttccaa acatggtcgg tgttaccaaa gcctgaacct
    36481 ccgccaaaat cggacgcgtc ccttccatgg ttacaacgat ggaggaacca gtcgccccat
    36541 ccaaacgctc ttctaggaaa acttgactcg gattgagtac ctcaaccaag ccgcccgact
    36601 gcatctcaaa aatcccaatc tcattagtgg aaccaaaacg atttttgacc gctctcaaaa
    36661 tacgaaaggt gtggtgacgc tccccttcaa agtaaagcac cgtatccacc atatgctcca
    36721 acatacgagg cccagccaag gttccttctt tggtcacatg acctacgata aagatggcaa
    36781 tgttattggt cttggccaac tgcatgagtt cagcggtcac ttcacgtacc tgagaaacag
    36841 acccctgcac ccctgaaatc tcaggagaca tgatggtctg gatggaatca ataatgagaa
    36901 agtctggctg gatacgctcc acttctgcac gaacactctg catattggtc tctgcataga
    36961 gataaaactc actatcaata tcacctaagc gctctgcacg tagtttaatc tgctgggcag
    37021 actcctcccc actgacatag agaactgtcc ccacttggga caactgggtt gagacttgta
    37081 ggagaagagt tgatttccca atcccaggat ccccaccgat gaggacgaga cttcctggta
    37141 ccactccgcc tccaagcaca cggttgaatt cctccatctc cgtcttggtt cgattgacat
    37201 tgatggaagt cacctcagct agtttcatgg gcttggtttt ctcacctgtc aaggacacac
    37261 gcgcattctt gacctcggca acctcaacct cttccacaaa agaagaccaa gacccacagt
    37321 tggggcaacg tcccagatat ttaggggaat tatacccaca attttgacat acaaatgtcg
    37381 cttttttctt tgcgatgaca aacctctttc tatatctcta actcacactc aatcacttgg
    37441 caaaaatcaa tcttctcatt tggcacaaac tggcgcatga gcattcgatg agcaacaact
    37501 accacagtct gatgttctcg atacttagac atacattcta gaaaccgaga cttcatttcc
    37561 gtagctgtct catattgaat aggactatta ggaagcaact cccccttgtt ttctaaaaac
    37621 agtcttctag ctgtttcaaa gttttctatt cctgttttat agacctgcca ttcatgtaat
    37681 aaaggctcta ctcttaaagg aagacccgta gcacagacca catacgaagc cgtttctaaa
    37741 gctcttgtga ctgcagaaga tacgattatt tcagctgacg agagtaaagg atttttgctc
    37801 aatttctgga cttgctgccg tcccatctca gacaagggtg ccaaatctat cccaaatcct
    37861 atataagaac gctcctctaa ctcacggtaa tctggctccc catgacgtac aaagataatc
    37921 ttcattctag tgccctgtcg atccaaatcc accagttcga acgccatcag ctgcatctcc
    37981 atctgcaatt aagaaagtag caaaaacagc ctggacaata cgttccccaa cttcaagaac
    38041 aacctcttgg tctgtgatat tcttcatctg cgcaaaaata tgcccttcat ttccaggatt
    38101 tccataataa tccccatcaa tgaccccaac tgagttaatt aaaaccaagc ccttcttacg
    38161 aggatttgaa gaacgatcat agaggtagag aacctcagtc ggctgcatat aagccttaac
    38221 ccctgtcgga accaagacaa tctctcctgg cgcaacaact gtacgcacag caacctttaa
    38281 gtcgtaacca gccgcatgcg ctgtctcacg cttgggcaat aaattttcat ctgtaaaact
    38341 cgaaaccaat tcaaaaccac gaattttcat aattttctct tttctattat catttattct
    38401 agattattct atcttattta ttcggaaaaa gcacgaaaaa aagagcacac aattcaaatc
    38461 gcttagggct gctggattcc tcccctgacc cgcttcacgc agaactgttg ctccactatt
    38521 tattatatca cattcctatt cattttaaaa gcaaaattat tttttccgtc tatttctaaa
    38581 aaaatcctgc atgatagctg cgcattcatc ttccaaaatt cctatttcaa cctccacacg
    38641 atgattgaga cgctcatctg tcaagatatc gtacaaactc ccagcagcgc caaatttctg
    38701 gtttttagcc ccatagacca catttggaat gcgggcaagc ccaatcgccc cactacacat
    38761 gacacaaggt tcaatggtca caaaaagtgt gcaatccagc aagcgccagc tctccttact
    38821 caagttcgca tcctctatag ccataatttc cgcatgcata accgctcgct gtaattcctc
    38881 acgcgcatta tgcccacgac caatgatttc cccatctttg acaatcacac aaccaattgg
    38941 aatttcatcg tgttcaagag caatctcagc ctctctcaaa gcctccctca taaagacttc
    39001 tttttcttca agcgtataat acatctcttt tctcttttcc tacttatcga ttttattatt
    39061 atatcatgaa tcccaacaca aaagaagcca ccgaatgcgg tgactctata gggagattat
    39121 tatgaaaaag aaaagtttag gatatttgtt acaacaagtt aggaggtctt cttgtaaccg
    39181 tctatagtat acccgaccta tcttaaacaa atcttaaaaa tctcttagga ccaaacactt
    39241 tctaaaatat ttgtttgttc acgaccagga cctactgaga aagtagaaat acgaacgcca
    39301 accaattcac tcacacgacg aacatagtta cgcgcattct caggaagatc ttccaaattg
    39361 cgaactccgg taatatcttc tgaccaacct ggcaactctt catagatagg cttgcaacgt
    39421 ttcaattgct caagactagc tggatagtag tcaatacgtt gaccgtcaag atcataggcc
    39481 acacagattt tcacagtatc caaaccgctc aaaacatcaa tagagttcaa agaaaggtta
    39541 gtaataccag aaacacgacg gctatgacgc atcacaactg agtcaaacca acctacacga
    39601 cgtggacgac cagttgttgt accatactca tgacccactt cacggatacg ttctcccact
    39661 tcatcaaaca actcagttgg gaaaggacca tctcctacac gactcgtata agctttacat
    39721 acacctacaa ccttgtcaat cttgcttgga ccgacaccag aaccaattgt cacaccacca
    39781 gctacagggt ttgatgacgt aacaaatgga taagtacctt ggtcgatatc tagcataaca
    39841 ccttgtgcac cttcaaaaag cacacgtttg ccattatcaa gcgcatcatt caagataaca
    39901 gatgtatcta tcacgtattt cttgatttgt tgaccatatt cgtaatattc ttcaaaaata
    39961 tcatcgaaaa caatcgcttt actgtcatac aatttttcaa aaagacgatt cttttcagca
    40021 aggttacgtt ctaaacgctc acggaaaata tctttatcta aaagatctgc aatacgaatt
    40081 ccaacacgag cagccttgtc catataagct ggaccaattc ccttaattgt cgtaccaatc
    40141 ttattgtcgc ccttagcttc ttcttgcaag cgatccaact cgatatgata aggcaaaata
    40201 acatgcgcac gatcagaaat acgcaagtta tcagttgtta caccttcctc atgaagatag
    40261 ctcaactctt ttacaagaga tttaggattt acaaccatac cattcccaat gacagatatt
    40321 ttttcaggga agaaaatccc agatggaatc aagtgcaact taaatttctt accgtcaatc
    40381 acaatcgtgt gaccagcatt atcaccacct tggtaacgtg caatcacttc tgcattcgct
    40441 gaaaggaagt ctgtaatctt ccctttacct tcatcacccc attgggtacc tacaacaaca
    40501 actgaagtca taattttgtc tgagccctca ggctcttcct ttctcacata catggcagga
    40561 ctctcacctg caattatatc ttacaattta ttataataaa aaatcgcctt tttatcaaga
    40621 agaaacaata gaaagatttg ctatttccaa ctattaaaaa atgatttaga aaaattacta
    40681 gctatttact attatctttc cataaaagag taaattagtt cggaaattta ctaaaattac
    40741 ctcaacaaga aataaaaccc cgattcatta ccaatttttc aagatacaaa cgataagcaa
    40801 cacgataatg gtaaacgata aaatccctat gacaaccaat gccatatctc actaaataat
    40861 aaattaaaaa tttaaaatga acatgttccc agtcaaaatt atcaccaaat gtaggaccat
    40921 actcttcttc aatactatca tagaaattag ccatctgctc ataaattttt tgtaacataa
    40981 tcaaatactc cttttctttt ttataaactt attctaacaa aaaattttac acattcacta
    41041 tcaattcctg aattgttaaa ataccagcct caacaagata aaaataggaa aagttgacaa
    41101 aatagaaaca aatttgctac ctaaatttca aacaattaaa gttctaaaaa gaccgcctta
    41161 aaacttttgg gtaaatccta ttagaactat aatattttta tataggtatt atggttctga
    41221 ttttctagta taaaaaaatt caaactagaa ttcttcttag aaaaggccgt tttaagtgct
    41281 atcattgctc aaaaatggag gttgctgaga cttctatcgt caagaagaat catcaaattc
    41341 cttgtatcat caaccaaaag attgctcaga agctaattga aaagacttct atgaccgaca
    41401 ttgatcatca gttgtctatt tcaacttcaa ctgtcattcg caagatcaat gattttcact
    41461 ttgagcatga tttttcgcgt cttcctgaga ttatgtccta ggacgttgaa acagtctggg
    41521 gagtgactgt ttcaatcggg agatagagat gagctttatt gctcaggact ttgataagct
    41581 caatatcata actgttcttg agagcagaac acaagccatc atccgaaatc ccatgaatac
    41641 aaggctatca agcgatactg aaagctcatt caacaagata gtcagaaact gagtgataaa
    41701 cgattttatc gccctacttt tcgtatgcac ttgactaata aagaaattct agataaactt
    41761 ttgagctatt ccgaagactt gaaacaccac tataatctct atcagctctt gcttttccac
    41821 ctctttttca gactctgttt aaaaccttcc tcaaagataa agagaaaatc gtcaacgccc
    41881 ttcaattacc ttattccaac gccaaactgg aagccaccaa taatctcatc aaacttatca
    41941 agcacaatgc ctttggtttt aggaactttg aaaacttcaa aaaagaaagg acgaaatttg
    42001 tcctttctag atcttcgctt tcttcaaccc actacagttg acaaagaacc gaaaaatgtc
    42061 tcgcctctaa tatagtcaat tgaaacaaga acaagacaaa agagcctcgt aaaaggtatt
    42121 gcaacttggt aatacctttt tgaggtgctt tttgatatga gcccatgttt tctcaatagg
    42181 attgtactca ggtgagtagg gaggaagatg taaaagttta tgcccaaact cttcgcataa
    42241 aagttctagc ttccccattc tatggaatct tgcattgtcc ataatatagt agattgaaac
    42301 tagaatagta cacctctact tctaaaacat tgttagaatt cgattttact gtcctaatcg
    42361 atttgtccta ttcttatttc attttactat aacacgaaat agattattat tacataacaa
    42421 aaaagaggtc taaacctctt aactcaatta ctccgccagt aggactcgaa cctacgacat
    42481 catgattaac agtcatgcgc tactaccaac tgagctatgg cggatta
//
LOCUS       DAVHSY010000013        41583 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.013, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000013 DAVHSY010000000
VERSION     DAVHSY010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41583
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.013"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            479..1522
                     /locus_tag="VVR43_000909"
     CDS             479..1522
                     /locus_tag="VVR43_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEU6149290.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            1689..3776
                     /gene="topA"
                     /locus_tag="VVR43_000910"
     CDS             1689..3776
                     /gene="topA"
                     /locus_tag="VVR43_000910"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU6149291.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEVASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3882..4241
                     /locus_tag="VVR43_000911"
     CDS             3882..4241
                     /locus_tag="VVR43_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU6149292.1"
                     /translation="MRLIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4334..4966
                     /locus_tag="VVR43_000912"
     CDS             4334..4966
                     /locus_tag="VVR43_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU6149293.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQLGVTQLHGTKVVF"
     gene            5010..5666
                     /locus_tag="VVR43_000913"
     CDS             5010..5666
                     /locus_tag="VVR43_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU6149294.1"
                     /translation="MFEIFKSYQFNQEKVHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5685..6317
                     /locus_tag="VVR43_000914"
     CDS             5685..6317
                     /locus_tag="VVR43_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEU6149295.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEECGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNICQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            6345..6779
                     /locus_tag="VVR43_000915"
     CDS             6345..6779
                     /locus_tag="VVR43_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEU6149296.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTINAVTDGIDAQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6791..7828
                     /gene="leuB"
                     /locus_tag="VVR43_000916"
     CDS             6791..7828
                     /gene="leuB"
                     /locus_tag="VVR43_000916"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEU6149297.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLVAIGSPQYDGVAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERIAGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VERIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFSDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSV
                     PDIAGQGIANPISMILSVVMMLRDSFGRYEDTERIKRAVETSLAAGILTRDIGGQAST
                     KEMMEAIIARL"
     gene            7825..8094
                     /locus_tag="VVR43_000917"
     CDS             7825..8094
                     /locus_tag="VVR43_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU6149298.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            8098..8457
                     /gene="leuD"
                     /locus_tag="VVR43_000918"
     CDS             8098..8457
                     /gene="leuD"
                     /locus_tag="VVR43_000918"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU6149299.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSKWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8619..9242
                     /locus_tag="VVR43_000919"
                     /pseudo
     CDS             8619..9242
                     /locus_tag="VVR43_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            9408..11339
                     /locus_tag="VVR43_000920"
     CDS             9408..11339
                     /locus_tag="VVR43_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEU6149300.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENSIFDMKRSTNEFIGRSAMVTK
                     LLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            11326..12642
                     /locus_tag="VVR43_000921"
     CDS             11326..12642
                     /locus_tag="VVR43_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU6149301.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLYINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFFVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKTEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            12817..13803
                     /locus_tag="VVR43_000922"
     CDS             12817..13803
                     /locus_tag="VVR43_000922"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU6149302.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            13867..13938
                     /locus_tag="VVR43_000923"
     tRNA            13867..13938
                     /locus_tag="VVR43_000923"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13900..13902,aa:Arg,seq:ccg)
     gene            14121..14819
                     /locus_tag="VVR43_000924"
     CDS             14121..14819
                     /locus_tag="VVR43_000924"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU6149303.1"
                     /translation="MKELQTVLKNHFAIEFTDKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14810..18349
                     /gene="smc"
                     /locus_tag="VVR43_000925"
     CDS             14810..18349
                     /gene="smc"
                     /locus_tag="VVR43_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU6149304.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELTQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQYIIVEDENAATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRQQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDRYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18346..19140
                     /locus_tag="VVR43_000926"
     CDS             18346..19140
                     /locus_tag="VVR43_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6149305.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSHDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEDGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELVKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            19140..19958
                     /locus_tag="VVR43_000927"
     CDS             19140..19958
                     /locus_tag="VVR43_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6149306.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSNQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGINQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            19962..21251
                     /gene="ftsY"
                     /locus_tag="VVR43_000928"
     CDS             19962..21251
                     /gene="ftsY"
                     /locus_tag="VVR43_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU6149307.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEADEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTIEENNSEVLEPERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRTGKKVMLVAADTFRTGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(21295..22782)
                     /locus_tag="VVR43_000929"
     CDS             complement(21295..22782)
                     /locus_tag="VVR43_000929"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU6149308.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(22931..23671)
                     /locus_tag="VVR43_000930"
     CDS             complement(22931..23671)
                     /locus_tag="VVR43_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6149309.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(23671..25836)
                     /locus_tag="VVR43_000931"
     CDS             complement(23671..25836)
                     /locus_tag="VVR43_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU6149310.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            26006..26959
                     /locus_tag="VVR43_000932"
     CDS             26006..26959
                     /locus_tag="VVR43_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6149311.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVALGQYRLDSIHLDTYSLAF
                     TLFTIPFWILQGTAEELVTRAWLIPQLAKRTNLKVAIIISSSLFTLLHLGNPGITFLS
                     AIDLFLFGVAMSLYLLKTDTIWGIGGIHGAWNFAQGNLFGVLVSGQSSGTSIMKFTPQ
                     GNQDWLSGGSFGIEGSIVSSIILFLLILYLAYQLKKENERM"
     gene            27036..29024
                     /gene="uvrB"
                     /locus_tag="VVR43_000933"
     CDS             27036..29024
                     /gene="uvrB"
                     /locus_tag="VVR43_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU6149312.1"
                     /translation="MINRITDNKFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVSKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            29034..29597
                     /locus_tag="VVR43_000934"
     CDS             29034..29597
                     /locus_tag="VVR43_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6149313.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNFGMMKLAEKLRMKKEAHIPKVRYYQGVY
                     YDSIKYGILREEWEEANGHHCQTDGNS"
     gene            29563..30051
                     /locus_tag="VVR43_000935"
     CDS             29563..30051
                     /locus_tag="VVR43_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6149314.1"
                     /translation="MVITVKQMETPEEIEGKSLVHWKAWRESYDDLLPAEFQETMTLE
                     RCRLFSQKYPENTLIAMDGLKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALDHFSEIFLWVLKDNKRAIAFYQKMGYTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            30124..30591
                     /locus_tag="VVR43_000936"
     CDS             30124..30591
                     /locus_tag="VVR43_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU6149315.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRSPDTNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWIQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKEIF"
     gene            complement(30588..31103)
                     /locus_tag="VVR43_000937"
     CDS             complement(30588..31103)
                     /locus_tag="VVR43_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU6149316.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(31115..31642)
                     /locus_tag="VVR43_000938"
     CDS             complement(31115..31642)
                     /locus_tag="VVR43_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6149317.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(31938..32501)
                     /locus_tag="VVR43_000939"
     CDS             complement(31938..32501)
                     /locus_tag="VVR43_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6149318.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(32485..33036)
                     /gene="coaC"
                     /locus_tag="VVR43_000940"
     CDS             complement(32485..33036)
                     /gene="coaC"
                     /locus_tag="VVR43_000940"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU6149319.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLITPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(33048..33737)
                     /gene="coaB"
                     /locus_tag="VVR43_000941"
     CDS             complement(33048..33737)
                     /gene="coaB"
                     /locus_tag="VVR43_000941"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU6149320.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLFAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISTDQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            33967..35637
                     /locus_tag="VVR43_000942"
     CDS             33967..35637
                     /locus_tag="VVR43_000942"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU6149321.1"
                     /translation="MKTDIEIGQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            35966..37141
                     /gene="mutY"
                     /locus_tag="VVR43_000943"
     CDS             35966..37141
                     /gene="mutY"
                     /locus_tag="VVR43_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU6149322.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            37196..37900
                     /locus_tag="VVR43_000944"
     CDS             37196..37900
                     /locus_tag="VVR43_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6149323.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            37893..39242
                     /gene="vicK"
                     /locus_tag="VVR43_000945"
     CDS             37893..39242
                     /gene="vicK"
                     /locus_tag="VVR43_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU6149324.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            39244..40053
                     /locus_tag="VVR43_000946"
     CDS             39244..40053
                     /locus_tag="VVR43_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU6149325.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            40144..40386
                     /locus_tag="VVR43_000947"
     CDS             40144..40386
                     /locus_tag="VVR43_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU6149326.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            40388..40642
                     /locus_tag="VVR43_000948"
     CDS             40388..40642
                     /locus_tag="VVR43_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU6149327.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQINVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            40689..41462
                     /locus_tag="VVR43_000949"
     CDS             40689..41462
                     /locus_tag="VVR43_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEU6149328.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENVFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIILVGSSILSVVEEKSFS
                     DSLWWTLVTVTTVGYGDIVPVSLLGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLQDELSSPRILLEKQSKKIEELHKMIQDLIEKT"
BASE COUNT        12850 a         7313 c         9216 g        12204 t
ORIGIN      
        1 actgttatag attcaataca ctataattta gtgtaattga gaaaggagaa atgattgtga
       61 ttgatgttgg ctaggttatt ttcaatgatt cctaccgtct caaatcttgt cagtaaggaa
      121 aaataaattc ttcaaaagta gagattacaa ggcttgttta agaaagaatt caaagacctt
      181 gacaaataaa aataaaatgg ttattataag aaatggtcta aaatagatga tgatactttt
      241 cgaaaatctt tttatgtcag ctcagctttg ccttgctgtg ttttgagcaa gctacggtta
      301 gcttccgagt ttgattttca tttactagaa atgaaactga tgagagatat cagtagacat
      361 ttgagtcagg atattatgga aaatgataaa aagagctcgt gagattggca tatcagacta
      421 ctaaagtatt gagtttgtta ggattttagc gactagttag ctgggaaagg aagatattgt
      481 gacaaataat aaactgtatt cgttgataga atttagaaat aaaatatatg aagaattaga
      541 actttccaga agtgatttag cgattttact atgtgccatg cttatcgcct ctatcggatt
      601 aaatatggat tcgactcccg tgattattgg agccatgtta atctctcctt tgatgacacc
      661 tattctggga gtggggctct ctctagctat atttgatttt aaattgttaa gaaaatcttt
      721 taaaatatta gctattcaaa ttcttgccag tttaatagct tcaacacttt atttttatct
      781 ttctcccatt tcgtatgcta gttcggaaat tgttgctaga acctctccga ctatttggga
      841 tgttctcatt gcttttgtag gagggatagc aggtattatt ggtgctagga aaaaagagac
      901 caataatatt gttcctggtg ttgctattgc aaccgccttg atgcctcctc tttgtacagt
      961 aggttatgct attgcttctg ctaatctaaa atttatcata ggctcctctt acctattcct
     1021 catcaattgt agctttattg tcattgcgac ttatataggt gttaggttga tgatggttaa
     1081 gaaacattat tttaaagata atgaagaaga ctctaaaatg cgtaggattt tgcttctagt
     1141 tgctgttttg ctgatgattc cgagtttcat ctctgcaacg actttagtga gagaaacgtt
     1201 gaaaaaagag tcccttaaga aatttatatc agagcagttt caggggcata atattttgaa
     1261 aaaaacctat tctaaaaaga ctcataccct aaagctaacc atttcaggaa attatttgac
     1321 agaagaagaa ctcgatatga tttcaagtaa gagaggtgac tatggtttaa gtgatgtttc
     1381 tgttcaagtt tcacaattgt ctgattcaga acaacttagt aaggaagaac tggtggagta
     1441 tttcttccag tatatcaagg ataaggaagc aaaagaaaag gaaaaagcta ataagtttta
     1501 tacagagtct gaggagcaat aatttcttga gaatagctgg tttttctcgt gagtcttcta
     1561 tgtatatcaa aggaagactg aggttttaag tataaaactt ttcttctatt atagtagcta
     1621 agtcttgaca gggttcaaaa aatggtttac actttataaa gtttattact ttgaaaaggt
     1681 gtgatactgt ggctacggca acaaaaaaga aaaaatcaac agttaaaaaa aatctagtca
     1741 tcgtggagtc gcctgctaag gccaagacga ttgaaaaata tctaggcaga aactacaagg
     1801 ttttagccag tgtcgggcat atccgtgatt tgaagaaatc cagtatgtcc gtcgatattg
     1861 aaaataatta tgaaccgcaa tatattaata tccgaggaaa aggccctctt atcaatgact
     1921 tgaaaaaaga agctaaaaaa gctaataaag tttttctcgc gagtgacccg gaccgtgaag
     1981 gagaagcgat ttcttggcat ttggcccata ttctcaactt ggatgaaaat gatgccaacc
     2041 gtgtggtctt caatgaaatc accaaggatg cagtcaaaaa tgcttttaaa gaacctcgta
     2101 agatcgatat ggacttggtc gatgcccaac aagctcgtcg gatcttggac cgcttggtag
     2161 ggtattcgat ttcgcctatt ttgtggaaga aggtcaagaa gggcttgtca gcaggtcgcg
     2221 ttcagtccat tgcccttaaa ctcatcattg accgtgaaaa tgaaatcaat gccttccagc
     2281 cagaagaata ctggacagtt gatgctgtct ttaaaaaggg aaccaaacaa tttcatgctt
     2341 ccttctatgg agtagatggt aaaaagatga aactgaccag caatgacgaa gtcaaggaag
     2401 tcttgtctcg tctgacgagt aaagactttt cagtagatca ggtggataag aaagagcgca
     2461 agcgcaatgc tcctttaccc tataccactt catctatgca gatggatgct gccaataaaa
     2521 tcaatttccg tactcgaaaa accatgatgg ttgcccaaca gctctatgaa ggaattaata
     2581 tcggttctgg tgttcaaggt ttgattacct atatgcgtac cgattcgact cgtatcagtc
     2641 ctgtagcgca aaatgaggtg gcaagcttca ttacggatcg ttttggtagt aagtattcta
     2701 agcacggtag caaggtcaaa aacgcatcag gtgctcagga tgcccatgag gctattcgtc
     2761 cgtcaagtgt ctttaataca ccagaaagca tcgctaagta tctggacaag gatcagctca
     2821 agctatatac ccttatctgg aatcgttttg tggctagcca gatgacagcg gccgtttttg
     2881 ataccatggc tgttaaattg tctcaaaaag gggttcaatt tgctgccaat ggtagtcagg
     2941 ttaagtttga tggttatctt gccatttata atgattctga caagaataag atgttaccgg
     3001 acatggttgt tggagatgtg gtcaaacagg tcaatagcaa accagagcaa catttcaccc
     3061 aaccgcctgc ccgttattct gaagcaacac tgattaaaac cttagaggaa aatggggttg
     3121 gacgtccatc aacctacgcg ccaaccattg aaaccattca gaaacgttat tatgttcgcc
     3181 tggcagccaa acgttttgaa ccgacagagt tgggagaaat tgtcaataag ctcatcgttg
     3241 aatatttccc agatatcgta aacgtgacct tcacagctga aatggaaggt aaactggatg
     3301 atgtcgaagt tggaaaagag cagtggcgac gggtcattga tgccttttac aaaccattct
     3361 ctaaagaagt tgccaaggct gaagaagaaa tggaaaaaat ccagattaag gatgaaccag
     3421 ctggatttga ctgtgaagtg tgtggcagtc caatggtcat taaacttggt cgttttggta
     3481 aattctacgc ttgtagcaat ttcccagatt gccgtcatac ccaagcaatc gtgaaagaga
     3541 ttggtgttga gtgtccaagc tgtcatcagg gacaaattat tgagcgaaaa accaagcgta
     3601 atcgcctctt ctatggttgc aatcgctatc cagaatgtga atttacctct tgggacaagc
     3661 ctgttggtcg tgactgtcca aaatgtggca acttcctcat ggagaaaaaa gtccgtggtg
     3721 gtggcaagca ggttgtttgt agcaaaggcg actacgagga agaaaagatt aaataagagg
     3781 aggggcccga aagtaaattt caggctcctt ttggttagaa cttgacaaaa tacatcattt
     3841 tatgcgaaac tagaagaaga ttattttaac taggagaagt tatgcgtctt atctatctga
     3901 taattggttt tttatcactg accttggcta ttgttggggt tgttttaccc ttgttgccga
     3961 caacgccttt ccttttgttg tctattgctt gtttctccag aagttccaag cgtttcgaag
     4021 actggcttta tcataccaag ctctatcaaa catatgtagc tgattttcgc gagactaagt
     4081 ctattacgcg tgaacgaaag aaaaaaatca tcgtctctat ctacgtcttg atgggaattt
     4141 ctatttattt tgcacctctt ttaccagtca aaatcggtct gggtgctttg accatcttta
     4201 tcacttatta tcttttcaag gtcattccag acaaagaata gttaaaacag tagttatttg
     4261 ccttgataaa attgaaagca tattcataac aatatgatat aataaatttg aagtaatatt
     4321 caaggagaat caaatgattt acgaattttg tgctgaaaat gtgactttac ttgaaaaagc
     4381 gatgcaggct ggagctcgtc ggattgaact ctgtgataat ctagcagttg gtgggacaac
     4441 acccagctat ggagtgacta aggcagcggt tgaactggca gctaactacg atacaaccat
     4501 catgaccatg attcggccac gtggtggtga ctttgtctat aatgacctag aaattgctat
     4561 catgctagaa gacattcgtt tgactgctca ggctggaagt caaggggttg tatttggagc
     4621 tttaactgct gataaaaagt tggataagcc taatctggaa aagttaattg ctgcatcaaa
     4681 aggaatggaa attgtctttc acatggcctt tgatgaacta agtgatgaag atcaaccgga
     4741 agctattgac tggctcagtc aagccggtgt cactcgtatc ctaactcgtg ctggtgtgtc
     4801 tggcgactcc ttagaaaaac gttttgttca ctatcacaga attttggagt acgctaaagg
     4861 taaaattgaa attctaccag gtggggggat tgaccttgac aaccgtcaaa cctttatcga
     4921 ccagttgggg gtaacacaat tgcatggtac taaggttgtt ttttaaaaaa tagaaaggaa
     4981 ctgctagctt tgggtagcag ttttcactta tgtttgaaat ttttaaatcc tatcaattta
     5041 atcaagaaaa ggttcatgat tatggtttta tagaaaatag cgaagtctgg acatatagtt
     5101 gccagatttt gcaaggtgac tttgtcatga ctgtgtccat cactgctgat aatgtgaact
     5161 ttcaagtctt tgaccaagag actggtgacc tctatcctca cgttcatatg gaaagcatga
     5221 ggggaagttt tgtcggaaat gtccgtgagg cttgtctgga gattctttac cagattcgga
     5281 aggcttgttt tgatgtgcaa gattttatct gtcatcagac taagcgtatc atgactcaag
     5341 ttcaggaaaa gtatggaaac cagttggagt atctgtggga aaaatcgcct gatacagctg
     5401 tattgcgcca tgaaggcaat caaaagtggt atgccgtctt gatgaaaatc tcttggaata
     5461 agctggaaaa gggcagagaa ggacaagtgg aagcagtcaa cctcaagcat gaccaagtag
     5521 ctaatttgct ttcacaaaag gggatttatc cagccttcca tatgagcaag cgctactgga
     5581 ttagtgtgtc ccttgatgat actttatcag atgaagaagt actggaattg atagaaaaaa
     5641 gttggaactt aacctctaaa aaatgaaata ttttaataat tttcatgaac tttcaattag
     5701 ctaaatattc tttactgaag aaattttcag aaaatatagg atttaccaca ccagaggaat
     5761 gtggtgccat cttcaaatac ctgattgaga atgtcaagac ggatcgtcag atcatctatt
     5821 cgcctcactg tcatgatgac ctcggaatgg cagtggcaaa tagccttgct gctgtcaaga
     5881 atggtgcagg acgtgttgaa gggactatca atggtattag ggagcgagct gaaaatgctg
     5941 ctttggaaga aattgcagtg gctctcaata tttgccaaga ttactaccaa gtagaaacca
     6001 gtattgtcct aaatgagacc atcaatacgt cagaaatggt ttctcgcttc tctggtattc
     6061 cagttcctaa aaacaaagcc gtcgttggtg gcaatacctt ctcccacgaa tctggtattc
     6121 accaagatgg agtccttaaa aatcctctca cttatgagat catcacacct gaattggttg
     6181 gtgttaagat tccgcttgga aaattatctg gtcgccatgc ttttgttgag aaactgagag
     6241 aattggccct agattttaca gaagaggata tcaaaccact ctttgctaag ttcaaggcac
     6301 tggccgataa gaagtaagaa atcacagatg cagatactcg agctttggta gctggaacca
     6361 tggttgaaaa tccagaaggc ttccactttg atgatttaca acttcaaact catgcagata
     6421 atgacattga agcgctcgtt agcctagcca atatggatgg tgagaaagtc gaatttaatg
     6481 cgacagggca aggttccgtt gaagcaatct ttaacgctat cgataagttc tttaaccaat
     6541 ctgttcgttt ggtgtcctac actatcaatg cggtaacaga tggaatcgat gcccaggatc
     6601 gggttttggt cactgttgaa aacagagata cagaaaccat ctttaatgca gcagggcttg
     6661 attttgatgt gttgaaggct tctgctattg cctatataaa cgctaatacc tttgttcaaa
     6721 aagagaatgc aggtgagatg ggacgcagtg tttcttacca cgatatgcct agtgtgtaaa
     6781 ggagaaggct atggcaaaga aaatagtagc tctagtagga gacggaattg gcccagaaat
     6841 catggaggct ggtttagaag ttctggaggc tctagctgaa aaaacaggtt ttgactatga
     6901 gattgacaga cgaccgttcg gaggtgcaga tattgatgca gcaggacctc ccttacctga
     6961 tgaaaccctt aaggcaagta gggaagcaga tgctatccta ctagtagcta tcggtagtcc
     7021 tcagtatgat ggagtagcgg ttcgccctga acaaggcctg atggctctcc gtaaggaact
     7081 caatctttac gctaatattc gtcctgtaaa aatctttgac agtctcaagt atttgtcacc
     7141 actcaaaccg gaacgaattg ctggtgtaga ctttgtcgtg gtgcgtgaat tgacaggcga
     7201 gatttacttt ggagatcata ttcttgaaga gcgcaaagcg cgtgatatca acgactatag
     7261 ctatgaggaa gtggagcgga ttattcgcaa agcctttgaa attgcaagaa atcgcagaaa
     7321 aatccttact agtatcgata agcaaaatgt tctagcgacc tcaaaactct ggcggaaagt
     7381 agctgaggaa gtcgcacagg atttctcaga tgtaaccttg gaacaccagc tggtagactc
     7441 agctgctatg cttatgatta ccaatcctgc taagtttgat gttattgtaa cggagaatct
     7501 ttttggagat attttatctg atgaatcaag cgtcttatct ggtacacttg gggttatgcc
     7561 atcagccagt cattctgaaa atggaccaag tctctatgaa cctattcacg gttcagtacc
     7621 tgatattgca ggtcaaggaa ttgccaatcc tatttccatg attttatcag ttgtcatgat
     7681 gttgagagat agtttcggac gttatgagga tacagagcgt atcaaacgtg ctgttgagac
     7741 aagtctggcg gcaggaattt taacgagaga tataggaggt caggcttcaa caaaggaaat
     7801 gatggaagct attattgcaa ggttatgaag ttagacgaaa aaattactct agtccttttg
     7861 atttggaatg tcatcatttt cttgatttat ggcattgaca aattcaaggc aagaagaaga
     7921 gcttggcgca tcccagagaa aatcttactc attttagccc ttacttgtgg tggttttggg
     7981 gcctggttag ctggaatcac ttttcaccat aagactcgaa aatggtactt taaaacagtt
     8041 tggtttcttg ggatggtgac cacactagta gccttatatt ttatttggag gtaatggatg
     8101 gcagggtctt cgagggaaca cgctgcttgg gctctagcgg actatggttt taaggtcgtg
     8161 attgcaggat ctttcggtga cattcattac aataatgaac tcaataatgg catgttgcca
     8221 atcgttcagc ctagagaggt tagagagaaa ctagcccagc taaaaccaac cgaccaggta
     8281 actgtggact tggaacaaca aaaaatcatc tcaccagttg aagaattcac cttcgagata
     8341 gatagcaagt ggaaacataa actcctaaat agtttggatg atatcggtat taccttgcag
     8401 tatgaagagt tgattgctgc ttatgaaaaa caacgaccag cctactggca ggattagaaa
     8461 aaatagaaaa ggaaatatag taaactgaaa taagatgtaa acaaatgaat tggagcttaa
     8521 catccatttc cagcaatttt ttagaaacta cagtggacta ttctggattc aacacattat
     8581 aaaattatga caaaacacat tcacaagaag gctacgacat tttaaaaggt gagggcggat
     8641 gtatcgtttg ccctactaaa gttggttaca ttatcatgac cagcaacaag gcaggacttg
     8701 agcgtaagtt cgcagccaaa gaacgtaagc gtaacaaacc aggtgttgtt ctctgcggta
     8761 gcatggatga acttcgcgct ttagcgcaac tcaacccaga aattgaagca ttctactaaa
     8821 aacattggat gaagatattc ttcttggttg tatccttcct tggaaaccag aagcctttga
     8881 aaaactcaaa gcatacgggg atggccgtga agaacttatg actgatgtac gtggtactag
     8941 ctgttttgtt atcaagtttg gaaaagcagg tgaacaattg gctgccaagc tttgggaaga
     9001 aggtaaaatg gtctacgcct catatgcttc aatgacaaaa cgattgaaac tcgctatgag
     9061 agcaaggtgt aatggtgtct atggtcgata aggacggcaa actcatccca gaacaaggag
     9121 gagcacgttc aacttcacca gcaccagttg tgatccgtaa agggcttgac attgataaaa
     9181 tcatgatgca cctgtcagat acttttaact catgggacta ccgtcaggtt gagtattatt
     9241 aagataaaaa aagaagtcta gtgttatgag atattaaagc ttctaacact ggactttttg
     9301 tttagaattt cttttctttt tctataggat atggtattct atgtagaaaa tatatgttaa
     9361 taagtaatgc caatatttaa acatcattag taaaaggagt tagattgatg aataaaagaa
     9421 aagttagttt agaagatttt tataaatggt atagtctaaa taaagaagag ttattaaata
     9481 aggcaactgt tggtgaaaag tttaatgata aattaaaaga agagtttctc caggaatggc
     9541 ctttggatag gattttaaca atgtcaatcg atgaatatgt aataggaaag ggacagcaaa
     9601 ataagtcttt atgctacgct cttgagaagg gaaaatacaa aaatctattt cttggaattt
     9661 ctggtggctc agcttcaaaa tttggtattt attggaataa aaaaacaaac aaatataaag
     9721 atcaagctaa taatgagatt tcagagttgg atcagcgatt ttcaaaatta aaatcagatt
     9781 tgtatgaaat tatcaaagaa ggtattcgtt ttaactttga aaattctatt tttgatatga
     9841 aaagatcaac aaatgaattt attggtcgtt ctgctatggt gacaaaatta ctttgtatct
     9901 attctgaggg agatcctttc tttggtgtaa atattaatag tcagaaagaa ttttggaacc
     9961 actttgtttc tcagacaaat caaggtggac cttatctgca aaatcataaa ataattgaac
    10021 tggtgtccaa aacttatcct gagttggagc catcgaaatt aggaactatg ctttttgagt
    10081 attctaagct ttttatggaa aataaggaag acaatagtac aatggattca tcaaacaatt
    10141 ttcgtcatca attaactcaa tctctattaa agtctccaaa ccttatcctt cgtggtgctc
    10201 ctggcacagg aaagacttat cttgctaaag aaattgccaa agaattaacg gatggcaacg
    10261 aagaccaaat cggatttgta caatttcacc catcatatga ttatacggat tttgtagaag
    10321 gtttaagacc agtatcaaat ggggatggag ctattgagtt taggctacag gacggtattt
    10381 ttaaagattt ttgtcagaaa gcaaaagaaa cccaattgat tggaggacaa gataattttg
    10441 atgaggcttg ggattcttac ttagaatata taaatgttgc tgaagaaaaa gaatatataa
    10501 caaaaacatc ttacttatct gttaatagta gacaaaattt gtcagtaaat tatgatagtg
    10561 gtgttccagg atggtcacta cctagcaaat atgtttacga gttgtataaa gataaaaatt
    10621 ataataagca agaatactac aaaagtggtg gaaaaactgt cctagaaaca ttgagaaaga
    10681 gatttggttt gaaagactat gtttccccaa cagaaattga tactgataag aaattcgtct
    10741 tcatcatcga tgaaatcaat cgtggggaga tttctaagat ttttggcgaa ctctttttct
    10801 ctatcgaccc tggctatcgt ggtgaaaaag gaagtgtttc tacccaatat gcaaatctac
    10861 acgaaactga tgaaaagttc tatatccccg aaaatgttta catcatcgga actatgaatg
    10921 atattgatcg ttcagtggat acctttgatt ttgctatgcg tcgtcgtttt cgttttgttg
    10981 aagttactgc cgagggtcaa gttggcatgt tggataaaga gctgaatatc catgcagaag
    11041 aagcaaaaat tcgtctaaga aacttgaacg ctgctatcga aaatgttcag gaattaaaca
    11101 gtcattatca tattggacca agttattttc ttaagttgaa ggatgtagat tttgactatg
    11161 aattactctg gtctgattat attaagcctc tcctagaaga ctacttgcga ggttcttatg
    11221 atgaggttga aactttggaa actttgaaaa aagcatttga actgacaaat aatgagcaaa
    11281 aagatcaggc agtagctgat gacaatgaag gtgatgaaaa cgatgatgcg gattactgat
    11341 aatcaacaca agattattaa agaaaaattt gttgaagaat atcctaaact aagcaatctc
    11401 cttttagaca gaaccttgga aagtctatcc caagatgaac gtattttcat ttttccaaat
    11461 gatttgactc atactcctga tttggataag gaccaaaaga tttttgaaac agtcaatcag
    11521 aaaatcaaga cagggaacgt gattggtttt cttggatatg gtcaggaaag attaacgatt
    11581 tcctcacgat tttctgatga gagtaatgac cattttttgc attatctctt aaacaaggtt
    11641 ctttatatca atctcactag tttagatgtt gctttgtctc gtgaagagag gctttatcaa
    11701 cttttgatgt atctcttccc caagtatcta caagccgcta ttcgaaaagg tctttataag
    11761 gaatatcatc gattttctca taacgacagt catgttaagg gagtgattga tgtaagaaac
    11821 catctcaaga aaaatcttcc tttcacggga aatattgcct acacaacgag agagttcacc
    11881 tatgataatc ccctcatgca gttggtccgt cacactattg aatacattaa gaatcagaaa
    11941 agcattggtc aaggggtact agataatctc tcaactagtc gtgaaaacgt atctgaaatc
    12001 gtgcgtgtaa cgccctctta taaactagct gatcgtgcta agattattcg gggaaatcaa
    12061 tctaaaccta tacgtcatgc atactttcac gagtacagaa acttacaaga actttgtctg
    12121 atgatcctaa accaagaaaa gcacggttta gggtatcaag atcaaaaaat ctatggtatt
    12181 ctctttgatg ttgcctggct ttgggaagag tatgtttaca ccttgttgcc aaaaggtttt
    12241 gtacatccca gaaataagga taagacggat ggaatttcag tattttttgt tgggaaacga
    12301 aaagtatatc cagattttta tgacagagaa cgaaagattg ttctagatgc aaaatataaa
    12361 aaactggaat tgactgaaaa aggaatcaac cgtgaggact tattccagct gatttcctat
    12421 tcttatattt taaaaactga gaaggctgga ctgatttttc ctagtatgga gcagtcagta
    12481 aatagtgaaa taggaaaagt agctggctat ggagctcaat tgaagaagtg gtctattcga
    12541 atccctcaga atgcctcatc ctatagtgca ttttgtaaaa tgatggaaaa ttcagaagaa
    12601 aattttaaag cgattattga tgaagaagtg gggagaaaat aatttcccct ctttctttta
    12661 tttttaacac aagtaaaacc cgaacgatat attttaattc ataaaataat ttgacaaaaa
    12721 ctgtactttg gtttataata aattaaggaa acgtcggaaa agacgtagtg atgcgagagc
    12781 ataggtaggt cattacaaaa gaaacgagac atcgatatgt taaatgaatt tccaattttt
    12841 gattacgaag atattcaatt gattccaaat aaatgtgtca ttaaaagccg tgcagaagcg
    12901 gatacaagtg tcactttagg aaatcacacc tttaaactac ctgttgtgcc agcgaatatg
    12961 cagacgattt tggatgaaaa tgtagcagag caactggcta aaggtggtta cttctacatt
    13021 atgcaccgtt ttgatgaggc aggacgcatt ccttttatta aacgaatgca cgatcaaggg
    13081 ctcattgctt ctatctctgt cggtgttaag gactatgagt atgatttcgt tagacagctc
    13141 aagactgatg ctcctgagta tatcactatt gatattgctc atggtcatgc ggatagcgtg
    13201 atttctatga ttcaacacat caagaaagaa ttgccagata cctttgtcat tgctggaaat
    13261 gtgggaacac cagaagctgt gcgtgaattg gaaaatgctg gtgcggatgc tactaaggtc
    13321 ggaatcggtc ctggtaaggt ttgtatcacc aaggttaaga ctggttttgg tacaggtggt
    13381 tggcagttgg ctgctctacg ctggtgtgcc aaggctgcgc gtaaaccgat tatcgctgat
    13441 ggaggaattc gtactcacgg tgatattgcc aagtctatcc gcttcggtgc tagcatgatc
    13501 atgattggtt ccctctttgc aggacacatt gaaagtccag ggaaaacgat tgaagtcgat
    13561 ggtgaacagt tcaaagaata ttatggttca gcctcacaat atcaaaaagg tgcttacaaa
    13621 aatgtggaag gcaaacgtat cttgcttcct gctaaaggtc atctgcaaga cactttaact
    13681 gagatggaac aagaccttca aagtgctatt tcttatgcag gtggacgtca ggttgctgac
    13741 cttaaacacg ttgattatgt gatcgtgaaa aactccatct ggaatgggga tgcttcccac
    13801 taagacgggg gctttgacta aaaaacttgt tattagagca aatttctgtt ataataaaac
    13861 aagtttccac ccttagtgta atggatatca cgtaagattc cggttcttga gatgggggtt
    13921 cgattccctc agggtggatg taaacatcct aaaaagcctt taatagggct tttttcttta
    13981 cactgatcta aatttgccgc taaaactgag aatctctgtc taaagaattc ccaaatgctt
    14041 tccagtcccg ttttagagtg actcaggggg ctttttttga tataataaaa aggactgtta
    14101 tcagttagaa agaggttggt atgaaagaat tacaaactgt actaaagaac cattttgcaa
    14161 tcgaatttac agacaaaaat ttactggaaa ctgcctttac tcatacgagt tatgccaatg
    14221 agcaccgcct cttaaaaatt tcacacaatg aacgcttgga atttttagga gacgctgttc
    14281 tacagttatt gatttcagaa tatctgtata aaaaatatcc taaaaagcct gaaggtgacc
    14341 tatcaaaact ccgtgctatg attgtccgtg aggagagttt agctggtttt gcgcgtgatt
    14401 gccagtttga ccagtttatc aagttgggta aaggggaaga aaaatctggt ggtcgcaatc
    14461 gtgacaccat tcttggtgat gcctttgaag cctttcttgg tgcccttctt ttggataagg
    14521 atgtggccaa ggtcaaggaa tttatctatc aagtcatgat tcctaaggtt gaagcaggcg
    14581 agtttgagat gattacagac tataaaaccc atctccaaga gttgcttcag gtcaatggtg
    14641 atgtggctat tcgttatcag gtgatttctg aaacagggcc tgctcacgat aaggtctttg
    14701 atgtagaagt tcttgttgaa ggtaagagca tcggtcaagg ccaaggtcgt tctaagaaat
    14761 tagcagagca ggaagctgcc aaaaatgccg ttgagaaggg gctggattca tgtatttaaa
    14821 ggaaatcgaa attcaggggt tcaagtcttt tgctgataag accaaggtcg tttttgacca
    14881 aggtgtgacg gcagttgttg gacccaatgg atctggaaag tccaatatta cagaaagtct
    14941 gcgttgggct ttgggggagt ctagtgtcaa gagtctccgt gggggcaaga tgccggatgt
    15001 catctttgct ggaaccgaaa gtcgcaaacc gctcaattat gcttctgtag ttgtgactct
    15061 ggataatcat gacggattta tcaaggatgc aggtcaagaa atcagggtgg aacgccatat
    15121 ctatcgtagt ggagatagcg aatacaagat tgacggcaag aaagtccgtc tgcgtgatat
    15181 tcatgacctc ttcttggata ctggattggg acgagattcc ttctctatca tttcccaagg
    15241 caaggttgag gagattttta attctaagcc tgaggaacgc cgagctattt ttgaagaagc
    15301 tgcaggagtt ttaaaataca agactcgtag aaaagaaact gagagtaaac tgcaacaaac
    15361 tcaggataat ctggaccgct tagaggacat tatctacgag ttggataatc aaatcaagcc
    15421 tcttgagaag caagctgaga atgcccgtaa gtttttagac ttggaaggac aacgtaaggc
    15481 tatttattta gatgttctgg ttgctcaaat caaggaaaat aaggctgaac tagagtcgac
    15541 agaagaagag ttgactcagg ttcaagaact cttgatgagt tattaccaaa agcgtgaaaa
    15601 attagaagaa gaaaatcaaa ctcttaaaaa gcaacgccaa gatttacagg ctgaaatggc
    15661 caaagaccaa ggcagtttga tggacttgac tagtctgatt agtgatttag aaagaaaatt
    15721 agccctatcg aaactggagt ccgagcaagt ggccttgaat caacaggagg cacaagcccg
    15781 tttggctgct ttggaggata agagaaattc actcagcaaa gaaaagtctg ataaagaaag
    15841 ctctttagct ctgttagagg gaaatctagt ccaaaataat caaaaactca atcgtttaga
    15901 agctgaattg ctggctttct cagacgatcc tgatcagatg attgagctct tacgtgaacg
    15961 ctttgtagct cttttacaag aagaagcgga tgtctcaaac cagttgaccc gtattgagaa
    16021 tgagttggaa aatagtcgtc agctttctca aaaacaagca gatcaactag aaaagctgaa
    16081 agagcaatta gctatagcta aagagaaggc tagtcagcaa aaggaagagc ttgaaactgc
    16141 caaggagcag gttcagaaat tattggctga ctaccaagct attgccaagg agcaagagga
    16201 gcagaaaact tcctatcaag ctcaacaaag ccaactcttt gaccgtctgg ataatctcaa
    16261 aaacaagcag gccagagctc aaagtttgga aaatatcctg agaaatcata gtaactttta
    16321 tgcaggtgtt aagagtgttc tccaagaaaa agatcgccta ggtgggatta ttggtgcagt
    16381 cagtgagcat ctgacctttg atatgcatta tcaaactgcc ctagaaattg cgcttggagc
    16441 gagcagtcag tacattattg tagaagatga gaatgcggca accaaagcca ttgatttcct
    16501 caaacgaaac agagccggtc gtgcaacctt tcttcctttg accactatta aggcgcgtac
    16561 gatttctagt cagaaccaag atgctatcgc tgtaagccca ggtttccttg ggatggcaga
    16621 tgagttggtg acttttgata ctagactgga agccattttc aagaacttgc tagctacgac
    16681 ggctatcttt gataccgtag aacatgcgcg tgcagcagct cgccaagttc gttatcaggt
    16741 tcgtatggtg acattggatg ggacagaatt acgcacgggt ggttcttacg caggtggagc
    16801 caatcgtcag aacaacagta ttttcatcaa gccagaactg gagcaattac aaaaagaaat
    16861 tgctgaagaa gaagcaagtt tgcgttcaga tgaagtgagt ttgaagaact tgcaagatga
    16921 gctagctaga ttgacagaaa gattagaagc catcaaatct cagggagagc aggctcgtat
    16981 tcaggagcaa ggcttgtccc tcgcctatca gcagaccagt cagcaagttg aagaactgga
    17041 aactctttgg aaactccaag aagaggaaat agatcgtctt tccgagggag attggcaagc
    17101 ggataaggaa aaatgccaag agcgtcttgc tgcaatcgcc agtgacaagc aaaatctgga
    17161 agctgagatt gaagagatta agtctaacaa aaatgccatc caagaacgct atcaaaactt
    17221 gcaggaagag ctagcgcaag ctcgtttgct taagacagaa ctgcaagggc aaaaacgtta
    17281 tgaagttgct gatattgaac gcttaggcaa ggaattggac aatcttgatt ttgaacaaga
    17341 ggaaatccag cgccttcttc aagaaaaggt tgataatctt gagaaggttg atacagaatt
    17401 gctcagtcaa caggcggaag aatccaaaac tcagaaaaca aatctccaac aaggtttgat
    17461 tcgccagcag tttgagttgg atgatataga aggtcaactg gatgatattg ccagtcattt
    17521 ggatcaggct cgccagcaga atgaggagtg gattcgcaag caaacacgtg ctgaagccaa
    17581 gaaagaaaag gtcagcgaac gcttgcgcca tctacaaagt caattaacag accagtacca
    17641 gattagctat actgaagctc tagaaaaagc gcatgaattg gaaaacctca atctggcaga
    17701 gcaagaagtt aaggatttag agaaggctat tcgctcactg ggtcctgtca atatagaagc
    17761 tattgaccgg tacgaagaag ttcacaaccg tctggacttt ctaaatagtc agcgagatga
    17821 tattttgtca gcgaaaaatc tgctccttga aaccattaca gagatgaatg atgaggtcaa
    17881 ggaacgcttt aaatcaacct ttgaagctat tcgtgagtcc tttaaagtga ccttcaagca
    17941 gatgtttggc ggaggtcagg cagacttgat attgactgag ggcgaccttt taacagctgg
    18001 tgtggagatt tctgttcaac ctccaggtaa gaaaatccag tcgcttaacc tcatgagtgg
    18061 tggtgaaaaa gctctatcgg ctcttgcctt gctcttctcc attattcgtg tcaagactat
    18121 tccatttgtt atcttggatg aggtggaagc tgcgctggat gaagctaatg ttaaacgttt
    18181 tggggattac ctcaaccgct ttgacaagga cagccagttc atcgtcgtaa cccaccgtaa
    18241 gggaaccatg gcagcggctg attctatcta tggagtgacc atgcaagaat caggtgtctc
    18301 aaaaattgtt tcagttaagt taaaagattt agaaagtatt gaaggatgac aattaaacta
    18361 gtagcaacgg atatggacgg aaccttccta gatgggaatg gacgctttga tatggatcgt
    18421 ctcaagtctc tcttggcttc ctacaaggaa aaagggattt actttgcggt ggcttcgggt
    18481 cggggatttc tgtctctgga aaaattattt gctgatgttc gtgatgacat tattttcatc
    18541 gcggaaaatg gcagtttggt agagtatcaa ggtcaggact tgtatgaagc gactatgtct
    18601 catgactttt atctggcaac ttttgaaaag ctgaaaacgt caccttatgt agatatcaat
    18661 aaactgctct tgacgggtaa gaagggttca tatgttctag atacggttga tgagacctat
    18721 ttgaaagtga gtcagcatta taatgaaaat atccaaaaag tagcgagttt ggaagatatc
    18781 acagatgaca ttttcaaatt tacaaccaac ttcacagaag aaacgctgga agatggggag
    18841 gcttgggtaa acgaaaacgt tcctggtgtt aaggctatga caactggctt tgaatctatt
    18901 gatattgttc tggactatgt cgataaggga gtggccattg ttgaattagt taaaaaactt
    18961 ggtatcacaa tggatcaggt catggctttt ggagacaatc ttaatgactt acatatgatg
    19021 caggttgtgg gacatcctgt agctcctgaa aatgcacgac ctgaaatttt agaattagca
    19081 aagactgtga ttggtcacca taaggaccag tcggttatag cttatatgga gggcttataa
    19141 tggcagatat aaaattaatc gcattggact tggacgggac cttgctgact actgataaaa
    19201 ggctgacgga tcgtaccaag gaaaccttga aagctgcgcg tgatcgtggt atcaaggtcg
    19261 tattgacaac tggtcgtccc ttaaaagcta tggatttctt tctccatgag ctagggactg
    19321 acggtcagga agatgagtat accattactt ttaatggtgg tttggttcag aaaaatacag
    19381 gtgaaatcct tgataagaca gtcttttcat atgatgatgt ggcacgcttg tatgaagaaa
    19441 cagagaaatt atcactgcct cttgacgcta tctcagaagg aactgtttat caaattcaat
    19501 cggaccaaga aagtctttat gccaaattca atccagcttt gacttttgtt ccagttgatt
    19561 ttgaagacct gtctaatcaa atgacctaca acaaatgcgt gaccgccttt gctcaagaac
    19621 ccttggatgc agccattcag aagatttctc cagaattgtt tgaccaatat gaaatcttta
    19681 aatcacgtga aatgttgcta gagtggtcac caaagaatgt tcataaagca acaggtttgg
    19741 caaaactaat cagccatctt ggaatcaacc aaagccaagt tatggcctgt ggtgacgagg
    19801 ccaatgacct ttctatgatt gaatgggcag gtcttggtgt tgctatgcaa aacgctgttc
    19861 ctgaagtaaa ggcagccgca aatgtagtaa cgccgatgac caacgatgag gaagctgtcg
    19921 cctgggctat cgaagaatat gtgctaaagg agaactaaga tatgggattg tttgaccgtc
    19981 tattcggaaa aaaagaagaa cctaaaatcg aagaagttgt aaaagaagct ctggaaaatc
    20041 ttgatttgtc tgaagatgtt gatcctacct tcacagaagc tgatgaagtt cctcaggaag
    20101 aagcagaggt tgaaattgtt gaacaagctg tgttccaaga ggaggaaatc caagacacag
    20161 ttgaagaaag tcaggattca gagccagctg taggggtttc tcaagaagaa atagaagaat
    20221 taccaaactc agaagaatta ccagaggaag agaagcttga gcacgaagga actatagaag
    20281 aaaataattc tgaagttctt gaaccagaaa ggcctcaaac agaagaaact gttcaggaaa
    20341 aatatgaccg cagtctcaag aagactcgta cgggcttcgg tgctcgcttg aacgccttct
    20401 ttgctaactt ccgctctgtt gacgaagaat ttttcgagga actggaagaa ctgctgatta
    20461 tgagtgatgt tggtgtccaa gtcgcttcta acttaacgga ggaactacgt tacgaagcca
    20521 agcttgaaaa tgccaagaaa cctgatgcac ttcgtcgtgt catcattgag aaattggttg
    20581 agctttatga aaaggatggt agctacgatg aaagcatcca cttccaagat aacttgacag
    20641 ttatgctctt tgttggtgtg aatggtgttg ggaaaacaac ttctattgga aaactagccc
    20701 accgctacaa acgaactggt aagaaggtca tgctggttgc agcagatacc ttccgtacgg
    20761 gtgcagtagc tcagctagct gaatggggcc gacgagtaga tgttccagta gtaactggac
    20821 ctgaaaaagc tgatccagcc agcgtggtct ttgatggtat ggaacgtgcc gtggctgaag
    20881 gtatcgatat tctcatgatt gatactgctg gtcgtctgca aaataaggat aaccttatgg
    20941 ctgagttgga aaagattggt cgtattatca aacgtgttgt gccagaagca ccacatgaaa
    21001 ccttcttggc acttgatgca tcaacaggtc aaaatgccct agtacaggcc aaagaatttt
    21061 cgaaaatcac acctttaacg ggaattgttt tgactaagat tgatggaact gctcgaggag
    21121 gtgtggttct agccattcgt gaagaactca atattcctgt aaaattgatt ggttttggtg
    21181 aaaaaatcga tgatattgga gagtttaact cagaaaactt tatgaaaggt ctcttggaag
    21241 gcttaatcta atcagaagca aaaatcctgc aaggtacaaa cttgcaggat ttttttattc
    21301 gaaacgacca tcttgacgat aggcgatatc tggttgccaa gtccatttgg caccgaattt
    21361 ttcaagtagg tcaaagctgg cttgaggtcc catgcttcca gctttatagt catgaagtgg
    21421 ggcaccattt tcagcccaga gcttttcaat acgatcaatc aacttccatg acgcaccaac
    21481 ttcatcccag tggctaaagt tggttgagtt gttatttagg acatcataaa tcaatttctc
    21541 gtatggttct ggagaagcac cagttgcagt cgcgtctgta cgataatcaa gtgagttagg
    21601 agccaagtta aattcttctc ctacttgctt cccatttagg ctaagagaga agccttctgt
    21661 tggttgaata tagatggtca aaatatttgg agcaagtggt tctccaaaga tagaatccat
    21721 ttgtttaaag acgatgttga catgagttcc tttttcagtc agtcgtttac ctgtacggaa
    21781 aaagaaagga acaccacgga atcgatcgct gtctacaaag aaggcaccag atgtaaaggt
    21841 ttcagttgtt gattctggat tcacatttgg ttcgctacga taagagatgt atttcatgcc
    21901 atcaatctta ccagagcggt attgcccacg gataaagtgt tctttgagtt cttcatcagt
    21961 tggatgatag aggtttttaa agaccttaat cttttcagca cgaatctcgt cttttgtgaa
    22021 gcttgctggt ttgtccatag cgaggagcga aagaagttgt agagtgtggt tttggaccat
    22081 gtcacggagg gcaccggatt ggtcatagta gccaccacgt tcttctacac ccaagcgctc
    22141 cgcaaaggta atttgaacat tgtcgataaa atccttgttc caaacgtttt caaaaatcaa
    22201 gtttgcaaag cgaactgcaa agatgctttg gatcatttcc ttaccaagat aatggtcgat
    22261 acggaaaatt tgttcttcgt caaatgttgc taggagttcg tcattcaact tgcttgcagt
    22321 tgcgtaatct gtaccaaatg gtttttcaac gatcaagcgc tcaaaacctt tgccatcgac
    22381 aatgttttca gatttgaggt gtttggcaat ggttccaaag aactgaggtg ccatagacaa
    22441 gaagaagagc ttattgtgtt cagcttggta tttttcatta agctcagctt gtaattgacg
    22501 caaagcaata taatgttccg aatcattgac atcatggctt tgatagtaga agtggctagc
    22561 aaattcttgg gcttgctcgg tactatctgc caaatcaagg atggactcga caactacaga
    22621 ttcaaaatat tccttactcc aaggtctacg ggcagttcca ataacggcaa agtgcttgga
    22681 aagattgccg gatttatata gtctaaaaag ggaagggtag agcttgcgtt tagccaggtc
    22741 tccactcgca ccgaaaattg taacaataac cttagatgac atctagctac ctaatttcta
    22801 tttttattcc tagtcttgct aggtatgagg aaacctcatt tcataaactt aattctaaca
    22861 taattttccg aaaaatcaaa aattccaata cgaggtagaa aaactgcaag gaaatcctta
    22921 cagtttgagt ttagacgttt aagaccttat ctaagaactc tttcagacga gggtgttgtg
    22981 ggttatcaaa gatttggtca ggtgttccgt cttcaaggaa ctcgccatct gcagtaaaga
    23041 taacgcggtt ggcaacctga cgagcaaatc ccatctcatg ggttacgata atcatggtca
    23101 tgccttgctc agccaattcc ttcataacgt taagtacgtc tccaaccatc tcagggtcaa
    23161 gggcagaagt tggttcatcg aagagcatga tgtctggatt cattgctagg ccacgagcga
    23221 tggccacacg ttgtttttga ccacctgata ggctatctgg attggcatta gctttatctg
    23281 ctagtccaac cttttcaagc aactccattc ccaattcctc agcttcttcc ttagtcatca
    23341 acttgtgctc aataggagca aaggtgatgt tgtccaatac agacatatga gggaagaggt
    23401 tgaagtgttg gaataccatg ccgatatttt cacggacgtg gtcaacattg gttgtttttt
    23461 cagttaaatc atagccgttc acagtgatgt gaccgctagt gacttcttct aaaagattga
    23521 ggctacggag gaaagttgac ttaccagaac ctgaaggacc gatgatacaa acaacatctc
    23581 cttcatagaa cttagtcgta attcctttta ggacttcatt ttttccatag tgcttgtgta
    23641 aatcatttac atcaattttt aattttgcca ttaacgaatc ctcttttcta agcgtttcgc
    23701 tagtctagtc aaaagtgtga taattacaag atagaagata gcaaggattg catacatctt
    23761 gaaactttgg tagttacgag caatgataat cttaccagtt tggaagagtt caaccaaacc
    23821 gatagcagat acgatagttg tatctttaag agcgataacg aattggttga caaagtttgg
    23881 caacatcaat ttagttgctt gtggcaagat aatcttacgc atggtttttc cataagagat
    23941 acccaagctt cggctggctt ccatttggcc aactggaacg gcctgaatac caccacgaac
    24001 gatttcagcg atataagcag ccgcattgag tgagagggca attgttccag ctacaaagtc
    24061 gttaattggg ctttgttggc ctgtgataga ctcgatgaag tttggaattc cccagaagat
    24121 gaaggctgca agaatcatca atggaatacc acgaataacg tcaacgaaaa tctcagagat
    24181 gacgcgaaga gatttgtatg ggctaacgct aaacataccg aagataattc cgatgacaat
    24241 ggcaatagca aatgagataa gagctagagc aagagtgata ccaagaccgc taaggagttg
    24301 tttgtagttg ttttgaagca agccccagag cgttgtttcg tcaacagtac ttgttgaagc
    24361 agttgaagat tcgctagcta ggtatttgtc aagaatcttt tggaattcac cgtttgcttt
    24421 aaggtttgca agtccgttgt tgaacatttc aatcagttct ggatttgctc cttttttaac
    24481 ggcaaaggct gtttcaccga ttggagttcc agagattgga gttttcaatt tttgaccttg
    24541 gctgatagaa tatttgagaa caggttcatc atccataacg gcatcaatgg caccagtgtt
    24601 taaactgtca tacattgaag aaccatcagc aaaggttttg attttgtaac cgtatttgct
    24661 ttgattttct gttaggaagg tttgagaagc agttccgttt ttaacaccga ctgtctttcc
    24721 ttttagatct tcataagaag caatattgct tgattctttg acaccaagaa tggtattagc
    24781 agtgtagtat gattctgaga agtcaaaagt tgccttacga gcatctgtga cagacatacc
    24841 agcaatgata ccatcggctt gaccagcttg gacagcactg atagcagcat caaaaccagg
    24901 gttggtgatt tcaatttcaa aaccttggtc tttagcgatt gccttaatca attccatatc
    24961 aataccagtg tattggttgc ttgaattttg gaaaacaaaa ggtgcaaaag aagaatcgct
    25021 ggcaatgata tatttagcct taacaggaat agcttttaat cctgcgagag tggttgtagt
    25081 tggcactgct gaagatgatg aagcagtcca tttcttgata attttatcaa gactaccatc
    25141 ttttttcatt tcagccaagg cttggttaaa ttcagtaacc aggtgttcgt atttacttcc
    25201 ttttttcaca ccgaaagcaa aacttcctac agcttcacca tccatttcaa tatggaggtc
    25261 ttgaccttgg ttaatggcat attcgataac aggtttgtca tccatcatgg catcgatggc
    25321 accagcactc aagctgttgt tcattaaatc cccagtgtca aatgttttaa tagtaaagcc
    25381 gtatttatct ttgattgttt caaggaaacg ttgagcggca gttccgtttt taacaccaac
    25441 ggttttgcca gttaattggt cgtacttgct aattttgtgt gactttgtag tagcaatgac
    25501 aacttttgta tcatagtaag tatcagacat ggtgaagact ttttcacgtt ctttagtctt
    25561 tgtcatccct gccatgatag cgtcggcttg cccagcttga accgcattga ctgctgcgtc
    25621 aaatccagga taggacatct gaatgttcca gcctttaatc tcagcgactt tgttaataat
    25681 gtcaacatca attcctttat aagtttgatc tgaatcttta aactcaaaag gtgcataggc
    25741 ggtatcagaa acaatcttaa tcgtttctgc tttggcaata cctaatgaga aaattgggaa
    25801 taaaattagc aaaaatgcta gaaatttttt cttcattttt agtctccttt tccgaatatt
    25861 ctctcattat atcagaaaaa gtaaaaaaag gcaaattttt atatttttcg tgtcagaaaa
    25921 tataacattg attttttcct ttccttgaat tgctattaaa aagtgctata ataatagtat
    25981 atatagaaga aaagaggacg gggatatgaa gaacaaaaga atatttaaag acttccaagc
    26041 ttcaaaaatg agtttaaaca tttacacaag ccccttgtta gcctttgttt ttgtcttcat
    26101 aggagagttt gtggctttta ctttgtatgg tattggcttg ttagctctca tcggacttgc
    26161 tagaaatttt ggagaggctg gtcaaaatct tgcaagctac ttgcagacct tgcatcagag
    26221 cttgacggat aaaacaagtg actttcgttt aattttagga ttactggcct ttggttttat
    26281 tcttaacact gtgttcagat ggacaagaaa agttgagaaa agacctattc gaaccttggg
    26341 attttataga gagaatttcc tcagcaatct tctgaaagga tttagtctag gtctggcact
    26401 ttttcttctg accttgttag gtttggtggc cttagggcaa tatcgtttgg actccattca
    26461 cttggatact tattcgctag cttttacttt atttacaata cctttttgga ttttacaagg
    26521 aacggcagaa gaattggtta ctcgtgcttg gctgattcca caattggcta agagaaccaa
    26581 tcttaaagtc gctattatca tatctagtag tctctttacc ttacttcatt taggaaatcc
    26641 aggcataact ttcttatctg caattgatct ctttttattt ggggttgcca tgtccctata
    26701 tcttcttaaa acagatacta tatggggtat aggtggtatt catggagctt ggaatttcgc
    26761 acagggcaac ctctttggag tattagttag tggtcagtct tcaggaacct caatcatgaa
    26821 atttactcca caaggcaatc aagactggct atctggtggg tcttttggta ttgagggttc
    26881 catcgtgtcc agtattattt tgtttctgct gattctttat ctcgcttacc aattaaagaa
    26941 agaaaatgaa aggatgtgac ttcggttcgt ccttttcttc gtgaaaatga tacaagtatg
    27001 ctaaaatagg aatagcacat ggagagagga ttcttatgat taaccgcatt acagataata
    27061 aatttaaact agtatcaaaa tatcaaccat caggagatca accccaagct atcgagcagt
    27121 tggtagataa tatcgagggt ggagaaaaag ctcagattct gatgggggcg accggaacag
    27181 ggaagaccta taccatgagt caggtcattt ccaaagtcaa taaacccact ctagtcattg
    27241 cccacaataa aactctggct ggtcagctct atggggagtt caaggaattt ttccctgaaa
    27301 atgcagttga gtacttcgta tcctactatg actattacca gccagaagcc tatgtccctt
    27361 ctagtgatac ctatattgag aaggatagtt ctgtcaatga cgagattgac aagcttcgtc
    27421 actcagcgac ttcagcccta ttggagcgca atgatgttat tgtcgtggcc tcggtctctt
    27481 gtatctatgg tctgggttcg cccaaggaat acgctgatag tgtcgttagt ctccgtccag
    27541 gtcttgaaat ttcccgtgat aaactcttga atgacttggt ggatatccaa tttgagcgaa
    27601 atgatattga tttccaacgg ggaagatttc gcgttcgtgg ggatgtggtg gagattttcc
    27661 ctgcttcccg tgatgaacac gcttttcgag tagaattttt tggagacgaa attgaccgta
    27721 ttcgtgaggt tgaagctttg acaggtcaag tccttggaga agtggatcat ttagcgattt
    27781 tccctgcgac tcactttgtg accaatgacg accacatgga agttgctatt gccaagattc
    27841 aagcagaatt agaagagcaa ctagctgtct ttgaaaagga aggcaaactg cttgaagccc
    27901 agcgcttgaa acaacggaca gagtacgata tcgaaatgct gcgtgagatg ggctatacca
    27961 acggggttga gaactattca cgtcacatgg atggacggag cgaaggagag cctccttaca
    28021 cacttcttga tttctttcca gatgatttct taatcatgat tgacgagagc cacatgacca
    28081 tgggacaaat caagggcatg tacaatggag accgttctcg taaggaaatg ttagtaaatt
    28141 acggtttccg tttgccgtct gctctggaca atcgtcctct ccgtcgggag gagtttgaaa
    28201 gccatgtgca ccagattgtt tacgtttcag cgacacctgg tgactatgaa aatgaacaga
    28261 ctgagacagt gattgagcaa atcattcgtc caacgggact cttggatcca gaggtggaag
    28321 tccgtccgac tatgggacag attgatgacc tcttaggtga aattaatgct cgtgttgaga
    28381 agaacgaacg aacctttatc accacgttga ccaagaaaat ggcagaagac ttgaccgact
    28441 acttcaagga aatgggtatc aaggtcaagt acatgcactc ggatatcaag acattggagc
    28501 ggactgagat tatccgtgac ctgcgcttgg gtgtctttga tgtcttggtc ggaatcaacc
    28561 tccttcgtga agggattgac gttcctgaag tgagcctcgt agcgattctt gatgctgaca
    28621 aggaaggttt ccttcgtaac gaacgtggac tcatccagac cattggacgt gccgcccgta
    28681 acagtgaagg tcatgttatc atgtatgcgg acacggttac ccagtctatg caacgtgcta
    28741 tcgatgaaac tgcccgccgt cgcaaaatcc agatggccta taatgaagag catggtatcg
    28801 taccacagac aatcaagaaa gaaatccgtg acctgattgc tgtgaccaag gcagtttcta
    28861 aggaagaaga caaggaagtt gatatcaata gcctcaacaa acaagagcgc aaagaacttg
    28921 ttaagaaact cgaaaaacaa atgcaagaag ccgtcgaagt gcttgacttt gaactagcag
    28981 ctcagattcg tgatatgatg ctggaagtga aggcgttgga ttaggggaat agtatgattt
    29041 atttaagaaa gttaaagaaa gaagatttga tgtctttatg ggaaatggct tattcacaac
    29101 ttaatccagt ttggaaacag tatgatgctc cctattatga tgattatcag tatttttcaa
    29161 attttaaaga attcgaacta caaaaatcag aatccatttt aagcaactca aatcgccttg
    29221 gtatttttgt tgatgataaa ctagttggga ctgtttcgcg ttattgggta tgtaaacaaa
    29281 caagatggat ggaattggga attggtattt atgataaaaa attctggaac actggtattg
    29341 ggaaagttgc tatgttgcag tggatagata ggacgtttca ggattacttg gagttggagc
    29401 atctgggttt gacaacttgg tcaggaaatt ttggtatgat gaaattggct gaaaaattaa
    29461 gaatgaaaaa agaagctcat attccaaaag ttcgttatta tcaaggtgtt tattatgata
    29521 gtattaaata cggcattttg agagaagaat gggaggaagc aaatggtcat cactgtcaaa
    29581 cagatggaaa ctcctgaaga gatagaaggt aaatcccttg ttcactggaa agcgtggaga
    29641 gaatcttatg acgacctttt gcctgcagaa tttcaagaga cgatgacatt agaaaggtgt
    29701 cgactcttta gtcaaaagta tccagaaaat acattgattg cgatggatgg cctgaaggta
    29761 gttggtttta tcagttatgg caactttcgt gatgagacta ttcaagctgg tgaaattatt
    29821 gctttatatg ttttaaaaga ctattacgga aaaggcatcg cacaaaagtt aatgaaagca
    29881 gctttgactg ctcttgatca tttttctgaa attttcttat gggtattgaa agataataag
    29941 cgcgccattg ctttctatca aaaaatgggt tatacttttg atggacaaga aaaaatactt
    30001 gaacttggaa agcctataaa ggaaaaacgg atggtattct attctaaata attttaaaaa
    30061 gtagaagctc atggcactgg taccaagtct aaaaatttaa taacttagaa agcgagtaaa
    30121 tttatgtccc gttcccaatt aacaatttta acaaatatct gtctgattga agacctcgaa
    30181 actcagcgcg tagtcatgca gtatcgctct cctgacacca atcgctggtc aggttatgcc
    30241 tttccaggag gtcatgtaga aaatggcgaa tctttcgcag agtctgtcat tcgtgaaatc
    30301 tatgaagaaa cagggttgac tatccaaaat cctcaacttg tcggcattaa aaattggcca
    30361 ctagatacag gtgggcgcta tattgtcgtt tgttataagg cgactgagtt ctctggtacc
    30421 cttcgctctt cagatgaagg agaggtttct tggattcaaa aagaccagat tccaaacttg
    30481 gatctggcct atgatatgct acctttgatg gagatgatgg aagctccgga caaatctgaa
    30541 tttttctacc ctcgccgtac agaagacgat tgggagaaag aaatttttta gtcttttact
    30601 aaataaccta gctgatccaa ggcctcctcg atatagtgga ggtcttgttg tgtttcggct
    30661 tcgactaggt ggtaatggac gccatctgtc aattcagata gaggtctaaa gtcagaatgc
    30721 tcgacttgtt ctagaaaatg ttgcacatct ctgcgacaag acagtttaag caaggtttca
    30781 atttctccat aaacgggatg gtcaatcaag gtattctgga catgcccgcc attatcgaca
    30841 atagcaagga gttcctgacc gatttcttca acttcatgtt tcactttgaa aagtttgtga
    30901 acataaggat tggtatcaat ttgcttatag atgtagccac gattggtgga taggatagga
    30961 gcgccatcgg ctctcaaaat tgcaatgtcc tgcacaatga cctgacgtgt gacatgaaaa
    31021 tgttccgcca aactttggcc attaagggct ttaggagctt ctttcaagag ttggagcagg
    31081 gcttgtttgc gatcttttgt catagctttt ccttttaacg gcgttttcga agcactttat
    31141 agacagctag tgctaatgta tagtctacca tactatggat aattgtgcca aatccaacta
    31201 gtacaaatag aacatagaac atgttttcta cattggtacc cgaagttgcg taaaaaagga
    31261 cacaggctaa tacttcagca agggcatgaa caacagccaa aacaaagttg aaaacccagg
    31321 aagattttgg tttatctagg gtatcgggga atttttgtag gtaaagagct cctaaagcac
    31381 caaaagatat atgggaaaaa gccctaaaaa cgataaccat gggatagcca gccatcaaaa
    31441 atccaaaact agaggctagg atgacaaaaa ctgccatcaa gggcgacaag aacatggcta
    31501 taaaaatagc gatgtggctc cccaaagtat aggaagcagg tggaatgaca atcttgaaag
    31561 gcataacaat tggaatcaaa atcgcaatag ccgttaaaag ggctgtcatt gtcataaatt
    31621 gtgtcttttt ccgtgtattc acaagaatct cctttttaac tgcatataca ctagtatggt
    31681 acaataaacc agacaataaa gcaagaattt acttgggttt atagatcatt ttttagttaa
    31741 aagttatagt agattgaaac tagaatagtt cacctctact tctaaaacat tgttagaaat
    31801 cgatttggct gtcctgatcg atttgtcctg ttcaatttgt cctgttctta tttcgtttta
    31861 ctatagtaaa gatttcatta aaaagaaact gtatagagca aaatctccac cttcaggttt
    31921 gaaagcggag attgttttta ttttttcaag gtttgtagtc gtggaacaat ggctagggtt
    31981 agaattgcag aaatgaccaa ttcagcaatt gaatttgttg agataacggt tgccagaaga
    32041 agttggatat ttccattata aacatttcca aataggaaga agattcctcc aaggacaaag
    32101 atagtatttg tcaaggaacc aagggcccca gctaaaatca gaccagtctt gtttttcatc
    32161 agtttataga ctaagtaagg agttaaacca atcaaaatac gtgggacaat ggcaatgata
    32221 gctgagtaga tgtttccgtt tggtacgaag ggagagaaga ggtagcttgt cggtagaatc
    32281 gtaatcgtgt taaccgtcaa gctaagtaat cccatcaaaa atccaagtgt aaccccaact
    32341 cgtggaccat aaataatgct ggcaataatg acaggaatat gaacaatggt cggtttgatt
    32401 ggaaatggaa aaaggttaaa gataagtgag ctcagaaagt gtatcacgag catggtagca
    32461 aaaaagatag caatgggtgc aatattagag cgttttttca tcgatagttt cctttattct
    32521 ttctaaaata attgtgaggt cagctaaagc tcctcgtccg tggtctccac aagctagtag
    32581 ggattcctta ggagcaatca gctgatagcc gtaggtttct aatgttttca gattattctg
    32641 agttactgga tggtcataca tttttgtatt catagcagga gttattagtt tgggaatatg
    32701 acttggtagg gctagagctg tactggttac catgttgtcc gcaaatccgt gagctagttt
    32761 tgcaatagtg ttagcagttg caggtaccac gataaataaa tctgcttttt ttccaagttc
    32821 gatatgattg acctgatcag gatagggttc cttcatgaca tccaagtgga caggattctg
    32881 tgagagtacc tgtagtgtca aaggttggat aaactctgta gcagcctgag tcattaagac
    32941 agtgacttga tggccttgtt tttttagaga actgactaaa tctgccgact tataagaggc
    33001 gattgaaccc gttacagcca agagaatgtt tgccatagtt ttcctttcta agaatgatag
    33061 gcttgaattt tttcaaggag gagttctgca atttcttctt tagtctggac tgtttgaagc
    33121 tgatttttct caacaaatat agctcggtgc tgatctgttg aaatttgagt caggtcattc
    33181 gcgatgatta aatctgcttg attcttgata agactttttc gtgcaatgtc aaccagatga
    33241 tcttcggtaa catcaaccag cagtttgaaa ccaatcagat gaatagtagg attccattcc
    33301 ttgactaggg atatgatttt gggtgtcttt ttaaggaaca aaacctgaac ctcatcagtt
    33361 gaagaaatct tggcctgatg attctgcttg cttaaaaatt cttttagatt ggagctagcc
    33421 tgaacttcct caagccctgt catataaaca ggagtgtagt cagaaacagc cattgagtgg
    33481 atcaagacct gataatcctg aacacgttct tgcatttcta ttagaaggtc cttggtattg
    33541 gtaatttctc gaatacttag gttaggatga ggctctggct tcagagctcg ttttgtcgta
    33601 attaaacaaa cttcatgccc tgcaaaaagc aaagtctctg tgataatttt ccccaagtga
    33661 cctgtagaat ggttagtgat agagcggacg ctatcgatag cttcactggt accgcccgat
    33721 gtaactaaaa ttttcatagc actattgtac acaaaaataa gcggtaagta aaatgaaagt
    33781 gataaatttt tggtaaaaac gaaaatttat tatagtttca aactataaag ccatataaaa
    33841 tttaagaaag gactctaaaa gtcttaaaaa cagagatatt tacgaacgtt tagagagttt
    33901 taggatgtta aaaatcttgt tttgtgatat aatgaattat catataagag gttagaggaa
    33961 ttttgaatga aaacagatat tgaaatcgga cagagtattg agttgaagcc aattgttgat
    34021 gttgtagaga aacttggtat ttcttacgac gatttggagt tgtacggaaa gtacaaggct
    34081 aaactcagct ttgataaaat tcgtgcagtt gagagcaatc cagtcggtaa attgatcttg
    34141 gttactgcca tcaacccaac acctgcaggt gaaggaaagt cgacgcttac cattggtctt
    34201 gcggatgcct tgaacaagat tggcaagaaa accatgattg ctatccgcga accgtctctt
    34261 ggtccagtca tggggatcaa gggtggtgct gctggtggtg ggtatgcaca agttctgcca
    34321 atggaagaca tcaacctcca ctttactgga gatatgcatg ctattacaac tgccaacaat
    34381 gccctttctg ccttgattga caaccacttg caccaaggga atgagctggg aattgatcaa
    34441 cgtcgtatcc tctggaaacg cgttgtggac ttgaacgacc gtgcgctccg ccatgtgact
    34501 gttggtcttg gtggtcctct aaacggtatt ccacgtgagg atggttttga tattacagtt
    34561 gcttcagaaa tcatggcaat tctttgcttg gcaacggaca tcgaggactt gaaacgtcgt
    34621 ttggcgaata tcgttattgg ttatcgctat gaccgtacgc ctgtttctgt aggtgatttg
    34681 caggttgagg gtgccttggc tttgattttg aaggatgcta ttaagccaaa cttggttcag
    34741 acaatttacg gtacacctgc ctttgtacac ggtggtccat ttgccaatat cgctcatggc
    34801 tgtaactctg ttttggcgac gacaacagcc cttcacttgg ctgattacac tgttactgaa
    34861 gctggttttg gtgcggacct tggtgctgag aaattccttg atatcaagac accaaacttg
    34921 ccaacatctc cagatgcagt tgttattgtc gcaacccttc gtgcccttaa gatgaatggt
    34981 ggtgtggcta aagacgctct gactgaagaa aatgtagagg cagttcgtgc aggttttgct
    35041 aacttgaaac gccacgttga aaatatccgt aagttcggta ttccagcagt tgtagctatt
    35101 aacgaatttg tatctgatac agaagctgaa attgcagcct taaaagaact ctgtgcctca
    35161 atcgatgtac cagttgaatt ggctagtgtc tgggctgatg gagcagaagg tggagtagca
    35221 cttgccgaaa cagttgttaa gacaattgct gaaaatccag ctaactataa acgtttgtac
    35281 gataatgacc tttctgtcca agaaaagatt gaaaaaattg tcactgaaat ctatcgtggt
    35341 agcaaagtga actttgagaa gaaagctcaa acacaaattg ctcaaatcgt tcaaaacggt
    35401 tgggacaaat tgccaatttg tatggctaaa actcaataca gtttctcaga caatccaaat
    35461 gcgcttggag caccagaaaa ctttgaaatt accattcgtg aattggtacc aaaattaggt
    35521 gcaggcttca tcgttgcctt aactggtgat gttatgacca tgccaggtct tccaaaacgt
    35581 ccagcagctc tcaacatgga tgttgaaagc gatggaactg tactaggctt gttctagtgg
    35641 attgaaattg actttaagtg agtttggaaa taatatccaa gctcattttt tctcagactg
    35701 caagcagttc atcaataaga tttatactct tcgaaaatct tttcaaacta cgtcagcttc
    35761 accttgccgt aggtaatatg atactgactc tgtcagttct atccacaacc tcaaaacagt
    35821 gttttgagca acctgcggct agcttcctag tttgctcttt gattttcatt gagtataagt
    35881 agatagaaaa gttatatact atctattgaa aatattataa atcagataca aagacaggtg
    35941 aaaccttctg tgttatacta gagatatgtt agatttgaaa gaatacggta tcgtcatgtg
    36001 gccggaggag aaagtcattt ctttccgtga gaaacttctc gcttggtatg atgaaaacaa
    36061 aagagatttg ccttggagga gaagtaaaaa tccttatcac atctgggtat ctgaaatcat
    36121 gcttcagcag accagggtgg atacagttat cccttactac gaaagatttt tggactggtt
    36181 tccaactgtc gaaagtctgg caactgcgcc tgaggagagt ttactgaaag cttgggaggg
    36241 cttgggttat tattctcgag ttcgcaatat gcaggctgca gcccagcaaa ttatgactga
    36301 ctttggtggc caatttccaa atacctatga aggaatttcc agcttgaaag ggattggacc
    36361 ttacacagca ggagccattt ccagtattgc ttttaacttg cctgagccag ctgtagatgg
    36421 taatgtcatg cgggtcttgg cgcgtctgtt tgaagtcaac cacgatattg ggattccaag
    36481 taatcgaaaa atttttcagg caatgatgga gatcttgatt aatccagatc gtccgggtga
    36541 ttttaatcaa gccttgatgg acttagggtc tgatattgag tctcctgtaa atcccagacc
    36601 tgaagaaagc ccagtcaagg actttagtgc ggcatatcag aatggaacca tggaccgtta
    36661 tccaattaaa tctcctaaga aaaagccggt tcctatttat cttaaagcct tagttgtgaa
    36721 aaattctcaa ggacaatttt tacttgaaaa aaatgaaagc gaaaagctct tggcaggttt
    36781 ttggcatttc ccctttatag aagttgataa cttttcgcaa gaagagcagt ttgacctctt
    36841 tcatcaggtt gcggaagaaa gtgtgaactc tggccccagt ccagaagaga gtttccagca
    36901 ggactatgac ctagatgttg attggcttga tgtttgtttt gatacagtcc agcatgtttt
    36961 tagtcatcga aaatggcatg tacagattgt agcaggtcag gtgagtgact tccatgattt
    37021 ttcagatagg gaagttcgtt ggctttcacc agaagaattc aagaattacc cacttgccaa
    37081 accccaacaa aaaatctggc aggcttatgc acaagccaac ttagacagta gccaagacta
    37141 gctattgtgt cttctgacta ttttttggta taatagtaga gaaaaaggtg aacatatgaa
    37201 aaaaatacta attgtagatg atgagaaacc aatctcggat attatcaagt ttaatatgac
    37261 caaggaaggt tacgaagttg taactgcttt taatggtcgt gaagcgctag agcaatttga
    37321 agcagagcaa ccagatatta ttattctgga tttgatgctt ccagaaattg atggtttaga
    37381 agttgctaag accattcgta agacaagcag tgtgcccatt cttatgcttt cagccaaaga
    37441 tagtgaattt gataaggtta tcggtttgga acttggggca gatgactatg taacgaaacc
    37501 cttctccaat cgtgagttgc aggcgcgtgt taaagctctt ctgcgtcgtt ctcaacctat
    37561 gccagtagat ggtcaggaag cagatagtaa acctcaacct atccaaattg gggatttaga
    37621 aattgttcca gacgcctacg tggctaaaaa atatggcgaa gaactagact taacccatcg
    37681 tgaatttgag cttttgtatc atttagcatc gcatacaggt caagtcatca cgcgcgaaca
    37741 cttgcttgag actgtctggg gttatgacta ttttggtgat gtccgtacag ttgatgtgac
    37801 tgtacgacgt ctgcgtgaga agattgaaga tacgcccagc cgaccagagt atatcttgac
    37861 gcgccgtggt gtagggtatt acatgagaaa taatgcttga tttactgaaa caaaccattt
    37921 ttaccagaga ttttatcttt atcctgattt tgttaggttt catccttgtt gtgaccctct
    37981 tattactgga aaatagacgt gataatattc agttgaagca aatcaatcaa aaggttaaag
    38041 atttgattgc aggagattat tccaaggttc ttgatatgca aggtgggtct gaaatcacca
    38101 atattaccaa taatttgaat gacttgtcgg aggttattcg tctcactcag gaaaatctag
    38161 aacaagagag taagaggcta aatagtattc tgttttatat gacagatggg gttcttgcga
    38221 ccaaccgtcg gggtcagatt atcatgatta acgatacagc caagaagcaa ctggggttgg
    38281 ttaaggaaga tgttctgaat agaagcattt tggaattgct caagatagaa gaaaactatg
    38341 aattgcgtga tttgattacc caaagtccag aattgttgct agattcccaa gatatcaatg
    38401 gcgaatattt gaaccttcga gttcgctttg ccttgatacg tcgagagtct ggctttattt
    38461 caggtttggt ggctgttttg catgatacga cggagcagga gaaggaagaa cgcgaacgaa
    38521 gactctttgt ttccaatgtt agccatgagt tacggactcc tctgactagc gtaaaatcct
    38581 atcttgaagc cttggatgag ggggctttgt gtgaaactgt agcaccagac tttatcaagg
    38641 tttctcttga tgagaccaac cgtatgatgc gcatggtgac ggatctcctc catctttcac
    38701 gtattgataa tgctaccagt cacctagatg tggaactgat taacttcact gcttttatta
    38761 cctttatcct caatcgtttt gacaagatga aaggacagga aaaggagaaa aaatatgagt
    38821 tggtgagaga ttatcccatc aattctatct ggatggaaat tgatacagat aagatgacgc
    38881 aggttgtcga caatatttta aataatgcta ttaagtattc gccagatggg ggtaaaatca
    38941 ctgtcagaat gaagacaact gaagaccaga tgattttatc catttctgac cacggtttgg
    39001 ggattcctaa gcaggattta ccacgtatct ttgaccgttt ctatcgtgtg gatcgtgcta
    39061 gaagtcgtgc acaaggtggt acaggtctag gactgtctat cgctaaagaa attatcaaac
    39121 aacataaggg ctttatttgg gccaagagtg aatacggcaa gggttcaacc tttaccattg
    39181 tgctccctta tgataaggat gcagtgaaag aagaagtatg ggaggatgaa gtagaagact
    39241 agaatgagtg aaataggctt taaatacagt attttagcgt cgggttccag tggaaattct
    39301 ttttatctgg aaacctcaaa aaagaagctt ttagtagatg caggcttgtc tggcaagaaa
    39361 attaccagtc tgctagctga aattaaccgt aagccagaag acctggatgc catcttgatt
    39421 acccatgagc attcagatca tatccatgga gtaggcgttt tggctcgcaa gtatggtatg
    39481 gatctttatg ccaatgaaaa gacctggcaa gctatggaaa atagtaaata tcttggcaag
    39541 gtggattctt cgcaaaagca tatttttgaa atgggtaaaa ccaaaacctt tggagatatc
    39601 gacatcgaga gttttggtgt aagccatgat gcagtcgcac cgcagttcta tcgctttatg
    39661 aaggatgata agagttttgt ccttttgaca gatacaggtt atgtcagtga ccgtatggcg
    39721 ggcattgtcg aaaatgcgga tggctatctt atcgaggcca accatgatgt agagattttg
    39781 cgatcaggtt cttacgcttg gcgactcaaa caacgaatcc tatctgacct tggtcacctt
    39841 tctaacgagg acggtgctga agctatgatt cggacgctag gaaatcgtac taagaagatt
    39901 taccttgggc atttatctaa ggaaaacaat atcaaggaac tggctcatat gaccatggtc
    39961 aatcagctgg ctcaagctga tctgggagtc ggagtagact ttaaggttta tgatacctca
    40021 ccagataccg caacaccatt gacagagata tagaaagaac gctgagaagg tgttcttttt
    40081 atattgactg aacacctaaa aagtaataca atggtgttac cattaaaaaa gggagcacaa
    40141 aagatgacta ctattacatt aaaagtttct gaagctgata aaacatttat gaaagcaatg
    40201 gctaagtttg aaggagtttc cctttcggaa cttattcgca ccaaaactct tgaagcccta
    40261 gaagatgaat acgatgctcg tgtggcagat ttagcctatc aagagtattt agaagacttg
    40321 gaaaaaggag ttgaacccat tacttgggaa gaaatgatgc atgatttagg cttgaaggat
    40381 gaataatttg tataaattag ttccaacaag acgtttcatc aagcaattga aaaaattgga
    40441 ccgttatacg cagaagctaa ttacaaacta tttacaaatc aatgttttgg aagacccaag
    40501 acgacacgga aaggctttgg ttggtaatcg cgttggtcaa tggcgctata gaattggtaa
    40561 ttatcgagtt atcgtacaaa ttgtagatga tgaattagtt gttgctactc tagaagttgg
    40621 tcatcggaga gatatttatt gaattaaagc tgagtaataa caatatagaa agtaaggaga
    40681 gtaaaaattt gaagaaaaaa tggttttttg cagattatta tgatacaaca attattttac
    40741 ttgctttaat ctctgttatt ctggtattac ttggatttgc tgagatgatt gatttggaca
    40801 atccgcctta tagtattatt gatttagtaa tctggggtgt ttttgtaatt gattatagtt
    40861 ggcgcttttt tattactaaa agaaaatggc gctttattct tgaaaatgtt tttgatttat
    40921 tggctattct ccctttaaat gctattttca cagtttttcg attagggcgt atctttcgtt
    40981 tagttaaact aacaaaatta ctgaaactga ctcgtttact tagaataatt ggacttacag
    41041 gtaaattaga aagaaaaatt agtagattct tacggacaaa tggcctgatt tatatcttat
    41101 atgttaatat ctttattatt ctagtaggaa gttcaatttt atctgtagtt gaagaaaaat
    41161 ccttctcaga tagtctttgg tggactcttg tgacagtaac tactgttggt tatggtgata
    41221 ttgttccagt ttcccttttg gggaaatggc tagcagtttt actgatgctt gtcggtattg
    41281 gaacaatagg gatgttaaca agtgctttga cgaacttttt tgtaaaggat aatccagatg
    41341 aacagataaa acttgataaa ctccaagatg aattatctag tccgagaata ttactagaga
    41401 aacaatctaa aaagatagaa gaactacata aaatgataca agatttgatt gaaaaaacat
    41461 aataaaaata aagatgagaa aaagtttgaa ctgaggagaa atcaagtaag ttttgacaca
    41521 atagaacgca tattatcagg tataaaaact tgatactatg cgttttattg tgggaagatg
    41581 tat
//
LOCUS       DAVHSY010000014        39780 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.014, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000014 DAVHSY010000000
VERSION     DAVHSY010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39780
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.014"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            9..89
                     /locus_tag="VVR43_000950"
     tRNA            9..89
                     /locus_tag="VVR43_000950"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Tyr,seq:gta)
     gene            94..164
                     /locus_tag="VVR43_000951"
     tRNA            94..164
                     /locus_tag="VVR43_000951"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:126..128,aa:Trp,seq:cca)
     gene            179..251
                     /locus_tag="VVR43_000952"
     tRNA            179..251
                     /locus_tag="VVR43_000952"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:212..214,aa:His,seq:gtg)
     gene            262..333
                     /locus_tag="VVR43_000953"
     tRNA            262..333
                     /locus_tag="VVR43_000953"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:294..296,aa:Gln,seq:ttg)
     gene            343..426
                     /locus_tag="VVR43_000954"
     tRNA            343..426
                     /locus_tag="VVR43_000954"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:377..379,aa:Leu,seq:caa)
     gene            533..1810
                     /locus_tag="VVR43_000955"
     CDS             533..1810
                     /locus_tag="VVR43_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU6149329.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYFFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            1886..3370
                     /locus_tag="VVR43_000956"
     CDS             1886..3370
                     /locus_tag="VVR43_000956"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU6149330.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDTSYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTVELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEISPIRHKTTVAAADMQAAVEAYLGL"
     gene            3431..4711
                     /locus_tag="VVR43_000957"
     CDS             3431..4711
                     /locus_tag="VVR43_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU6149331.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLLGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4715..5335
                     /locus_tag="VVR43_000958"
     CDS             4715..5335
                     /locus_tag="VVR43_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU6149332.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSDFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5501..6643
                     /locus_tag="VVR43_000959"
     CDS             5501..6643
                     /locus_tag="VVR43_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU6149333.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVIVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQETTPAEKQETQASPQAASAVEVTTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            6966..7391
                     /locus_tag="VVR43_000960"
     CDS             6966..7391
                     /locus_tag="VVR43_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU6149334.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAIQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7402..7803
                     /locus_tag="VVR43_000961"
     CDS             7402..7803
                     /locus_tag="VVR43_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEU6149335.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATRSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKIHLKVDSNLANPF"
     gene            7878..8522
                     /gene="pcp"
                     /locus_tag="VVR43_000962"
     CDS             7878..8522
                     /gene="pcp"
                     /locus_tag="VVR43_000962"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU6149336.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(8550..9407)
                     /locus_tag="VVR43_000963"
     CDS             complement(8550..9407)
                     /locus_tag="VVR43_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU6149337.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9537..10679
                     /gene="tgt"
                     /locus_tag="VVR43_000964"
     CDS             9537..10679
                     /gene="tgt"
                     /locus_tag="VVR43_000964"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU6149338.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            10780..12597
                     /locus_tag="VVR43_000965"
     CDS             10780..12597
                     /locus_tag="VVR43_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU6149339.1"
                     /translation="MRIKWFSLIRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGNYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQSRSN
                     GQLRGMVFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSILATIVGV
                     RQTTSLVKQLDKIWDLRKTLLVFAGGFGFLLILTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTPNVQEPKMISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPVLQTLRPLPYIHAILATSTGILVFIVFLVTLLAPQV
                     GAFETDLTVNGLKQAASNIAQTKVMAERAEADSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSRTTKTANEIMLNNSQNKFLPKMVVIATGVNNPENYKEDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITVADWNQVAKEHPEIWAG
                     TDQVHFGSDTSTIEAGAKLYAETIATALQTAQDKPVKSK"
     gene            12750..13901
                     /gene="nagA"
                     /locus_tag="VVR43_000966"
     CDS             12750..13901
                     /gene="nagA"
                     /locus_tag="VVR43_000966"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU6149340.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14064..15122
                     /locus_tag="VVR43_000967"
     CDS             14064..15122
                     /locus_tag="VVR43_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU6149341.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15273..15638
                     /locus_tag="VVR43_000968"
     CDS             15273..15638
                     /locus_tag="VVR43_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU6149342.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            15714..16655
                     /locus_tag="VVR43_000969"
     CDS             15714..16655
                     /locus_tag="VVR43_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU6149343.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            16603..17619
                     /locus_tag="VVR43_000970"
     CDS             16603..17619
                     /locus_tag="VVR43_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU6149344.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            17621..17947
                     /gene="comGC"
                     /locus_tag="VVR43_000971"
     CDS             17621..17947
                     /gene="comGC"
                     /locus_tag="VVR43_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEU6149345.1"
                     /translation="MKKMMTFLKKSKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLQADGRITEEQAKAYKEYHDKNGVA
                     NRKVND"
     gene            17940..18344
                     /locus_tag="VVR43_000972"
     CDS             17940..18344
                     /locus_tag="VVR43_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU6149346.1"
                     /translation="MIKAFTMLESLLALSLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTISNGSQKLPVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18349..18609
                     /locus_tag="VVR43_000973"
     CDS             18349..18609
                     /locus_tag="VVR43_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149347.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVNINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            18572..19033
                     /locus_tag="VVR43_000974"
     CDS             18572..19033
                     /locus_tag="VVR43_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU6149348.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRFYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19011..19424
                     /locus_tag="VVR43_000975"
     CDS             19011..19424
                     /locus_tag="VVR43_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU6149349.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKKSEEKPEKKENS"
     gene            19561..20148
                     /locus_tag="VVR43_000976"
     CDS             19561..20148
                     /locus_tag="VVR43_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6149350.1"
                     /translation="MKHDFNHKAETFDSPKNIFLANLVCQAVEKQIDILSDKEILDFG
                     GGTGLLALPLAKQAKSVTLVDISEKMLEQARLKAEQQAIKNIQFLEQDLPKNPLEKEF
                     DCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIE
                     HGFSSVNSQILYSAEDLFQGNYSEFFLIVAQKSLA"
     gene            20209..21162
                     /locus_tag="VVR43_000977"
     CDS             20209..21162
                     /locus_tag="VVR43_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6149351.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21213..22403
                     /locus_tag="VVR43_000978"
     CDS             21213..22403
                     /locus_tag="VVR43_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU6149352.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22552..22923
                     /gene="rnpA"
                     /locus_tag="VVR43_000979"
     CDS             22552..22923
                     /gene="rnpA"
                     /locus_tag="VVR43_000979"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU6149353.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            22898..23722
                     /locus_tag="VVR43_000980"
     CDS             22898..23722
                     /locus_tag="VVR43_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU6149354.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            23741..24727
                     /locus_tag="VVR43_000981"
     CDS             23741..24727
                     /locus_tag="VVR43_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU6149355.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSRTFYVTINVNDYVEHRAEVLQTYAQKL
                     ATRVLEEGRNHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            24778..25401
                     /locus_tag="VVR43_000982"
     CDS             24778..25401
                     /locus_tag="VVR43_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU6149356.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMIALRLYGNPSDF
                     GISLEVSFIERKKDEQTLGKQAKVLEIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYQVTRG"
     gene            25530..26987
                     /locus_tag="VVR43_000983"
     CDS             25530..26987
                     /locus_tag="VVR43_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU6149357.1"
                     /translation="MEVVSNVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLIIIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLAAYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27010..27291
                     /locus_tag="VVR43_000984"
     CDS             27010..27291
                     /locus_tag="VVR43_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6149358.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQRDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27367..27852
                     /locus_tag="VVR43_000985"
     CDS             27367..27852
                     /locus_tag="VVR43_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6149359.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            27869..28534
                     /locus_tag="VVR43_000986"
     CDS             27869..28534
                     /locus_tag="VVR43_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU6149360.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            28538..29401
                     /locus_tag="VVR43_000987"
     CDS             28538..29401
                     /locus_tag="VVR43_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU6149361.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYGTGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SRGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29403..30107
                     /locus_tag="VVR43_000988"
     CDS             29403..30107
                     /locus_tag="VVR43_000988"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU6149362.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30290..31963
                     /locus_tag="VVR43_000989"
     CDS             30290..31963
                     /locus_tag="VVR43_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU6149363.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32075..33166
                     /gene="ulaG"
                     /locus_tag="VVR43_000990"
     CDS             32075..33166
                     /gene="ulaG"
                     /locus_tag="VVR43_000990"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU6149364.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33280..35256
                     /gene="tkt"
                     /locus_tag="VVR43_000991"
     CDS             33280..35256
                     /gene="tkt"
                     /locus_tag="VVR43_000991"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU6149365.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            35373..35672
                     /gene="yajC"
                     /locus_tag="VVR43_000992"
     CDS             35373..35672
                     /gene="yajC"
                     /locus_tag="VVR43_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU6149366.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            35718..36146
                     /locus_tag="VVR43_000993"
     CDS             35718..36146
                     /locus_tag="VVR43_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU6149367.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36148..36558
                     /locus_tag="VVR43_000994"
     CDS             36148..36558
                     /locus_tag="VVR43_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149368.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            36858..39509
                     /gene="adhE"
                     /locus_tag="VVR43_000995"
                     /gene_synonym="adhC"
     CDS             36858..39509
                     /gene="adhE"
                     /locus_tag="VVR43_000995"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU6149369.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12103 a         7113 c         8935 g        11629 t
ORIGIN      
        1 tatattttgg aagggtagcg aagaggctaa acgcggcgga ctgtaaatcc gctccttcgg
       61 gttcgggggt tcgaatccct ccccttccat tttacgggca tagtttaaag gtagaactaa
      121 ggtctccaaa accttcagtg tgggttcaat tcctactgcc cgtgttaata gaattatggc
      181 gggtgtggtg aagtggttaa cacaccagat tgtggctctg gcatgcgtgg gttcgatccc
      241 catcactcgc ctattttata ttggggtata gccaagcggt aaggcaaggg actttgactc
      301 cctcatgcgt tggttcgaat ccagctaccc cagttactat ttgccggcgt ggcggaattg
      361 gcagacgcgc tggactcaaa atccagtgtc cgcaaggacg tgccggttcg accccggccg
      421 ccggtatagt atagtgttag gaacgttgtt attcttcgtt ccttttttat attatttttg
      481 gtataattat agttattcaa attttattta gattaagaaa gtgtagggta gtatgtcttg
      541 ttctatcgat ttattaaaac atcggtattt gaaaaatatt aaagaaaatc ctgaattgtt
      601 tgtcggaatt gagttggagt atcctgttgc aagtttagaa ggggatgcta cagatgttga
      661 agttataaag gatctatttc attatttagt ttctactttg gatctcaccg tagcaaaggt
      721 agatgatttt ggcaatctga tccagttagt agatccgata agtcaggatg ctattttatt
      781 tgaagtttcc tatacaacga ttgagtttgc atttggtaag gctgaaacga ttcaagaggt
      841 cgaaaatcgt ttcaataatt atatgaatgt aattcagaga aagttagctg aatcaaatca
      901 tgctattgtt ggctgtggta tccatcccaa ctgggataaa aatgagaatt gtccagtggc
      961 ttatccacgc tatcagatgt tgatggatta tttgaatttg agtagaaata ttattaaatc
     1021 agatttacat catttccctg aatatggtac ttttatctgt gggagccagg ttcagctgga
     1081 tatttcaaaa accaactact tacgggtgat taatgctttt actcaaattg aagcggctaa
     1141 ggcttatttc tttgcaaact ctgaattttc gggtgcggat tgggatacga aaatttcaag
     1201 ggatattttc tgggaagaat ctatgcatgg tatctatcca gagaatgttg gggtcaatgc
     1261 tagactcctt aatgatgaag ctgatttttt tgactatcta aatcattctg cgatttttac
     1321 tgcggaacgt gatgggcaga cctattattt ttatcctatt caggctgggg actatttggc
     1381 tacgcctgaa atccaagcat ttgctctgaa tggggatgag gttattattt ccccccaaga
     1441 gaaggatttt gaaactcatc gtagttacca gtaccaagac ttaacgactc gaggaacagt
     1501 tgagtttcgt agtgtgtgta cacagccact tgataggact tttgcttctg cagcttttca
     1561 cttgggatta ttggttaatt tagacaagtt agaagcttac ttagaaacag cacctttctt
     1621 taaagtattt ggttatgatt acaagtcttt aaggagacaa ttttctaaga aaaatcttac
     1681 agatgaggaa gaaactacga ttattgaatt ttccaaagac ttactcctac tagctgagga
     1741 gggactagtg gtgagaaata aggaagaaat gacctattta cagcctttga gagaagaatt
     1801 gagcctataa tttctcttat aaagggagaa ttttctgaaa aatcatgata taatggacga
     1861 gactatagat aaaggataga gagtaatgac attagtttat caatcaacgc gtgatgccaa
     1921 caatacagta actgctagcc aagcaatttt gcaaggtttg gcgacggacg gcggtttgtt
     1981 tacaccggtt acttatccaa aggtagattt ggactttgac aaattgaaag atacttctta
     2041 ccaggaagtt gctaagctag ttttgtcagc atttttagat gactttacag ctgaggagtt
     2101 ggactactgt atcaacaatg cctacgatag caaatttgat actccagcta ttgcaccatt
     2161 agtgaaatta gatgggcaat acaatttgga acttttccat ggttcaacga ttgcctttaa
     2221 ggatatggcc ttgtctattt tgccatactt tatgacgact gctgctaaga aacatggttt
     2281 ggagaacaag attgttatct tgacagcaac atctggtgac acggggaaag ctgctatggc
     2341 ggggtttgcg gatgtgcctg gtactgagat tatcgtcttt tatccaaagg atggtgtcag
     2401 caagattcaa gagttacaaa tgaccactca aactggcgac aatactcatg ttattgctat
     2461 tgatggtaac tttgacgatg cgcaaacaaa tgtgaagcac atgtttaacg acgtggctct
     2521 tcgtgaaaaa ttgactacca acaagttgca attttcatca gctaactcta tgaacattgg
     2581 tcgtctggtg ccacaaattg tttattatgt ttatgcttac gctcaattgg tcaagactgg
     2641 tgagatcgtg gctggtgata agattaactt cacagtacca acaggaaact ttggaaatat
     2701 cttggctgcc ttttatgcca aacaaatcgg tctcccagtt ggtaaattga tctgtgcttc
     2761 aaatgacaac aatgttttga cagacttctt caagacacgt gtttacgaca agaaacgtga
     2821 gtttaaggta acaaccagcc catctatgga tatcttggta tcttcaaact tggagcgctt
     2881 gattttccat cttttgggaa ataatgctga aaagacagtt gaacttatga atgccttgaa
     2941 cacgcaagga caatataagt tgacagactt tgatgcagag attttggacc tctttgcagc
     3001 tgaatatgcg actgaggaag aaacggcagc agagatcaag cgtgtttgtg agttagattc
     3061 ttatatcgag gaccctcata cagctgttgc ttcagcagtt tataaaaaat accaatcggc
     3121 cactggagat gtaactaaga cagtgattgc ttcaacagct agtccataca agttcccagt
     3181 agttgcagta gaagctgtaa ctggaaaagc aggtttaaca gactttgaag ccttggctca
     3241 attacatgaa atctcaggcg ttgcagtgcc accagcagtt gatgggcttg aaatatctcc
     3301 aattcgtcac aagacaacag tggcagctgc tgacatgcaa gcagcggttg aggcttattt
     3361 aggactttaa gacagaggga gcaaactcgg ttgggaaacc aactgagttt cttttcatca
     3421 ggaggagaga ttgtttaaga aaaataaaga cattcttaat attgcattgc cagctatggg
     3481 tgaaaacttt ttgcagatgc taatgggaat ggtggacagt tatttggttg ctcatttagg
     3541 attgatagct atttcagggg tttcagtagc tggtaatatt atcaccattt atcaggcgat
     3601 tttcatcgct ctgggagctg ctatttccag tgttatttca aaaagcatag ggcagaaaga
     3661 ccagtcgaag ttggcctatc atgtgactga ggcgttgaag attaccttac tattaagttt
     3721 ccttttagga tttttgtcca tcttcgctgg gaaagagatg ataggacttt tggggacgga
     3781 gagggatgta gctgagagtg gtggactgta tctatctttg gtaggcggat cgattgttct
     3841 cttaggttta atgactagtc tgggagcctt gattcgtgca acgcataatc cacgtttgcc
     3901 tctctatgtt agttttttat ccaatgcctt gaatattctt ttttcaagtc tagctatttt
     3961 tgttctggat atggggatag ctggtgttgc ttgggggaca attctgtctc gtttggttgg
     4021 tcttgtgatt ttgtggtcac aattaaaact gccttatggg aagccaactt ttggtttaga
     4081 taaggaactg ttgaccttgg ctttaccagc agctggagag cgacttatga tgagggctgg
     4141 agatgtagtg atcattgcct tggtcgtttc ttttgggacg gaggcagttg ctgggaatgc
     4201 aatcggagaa gtcttgaccc agtttaacta tatgcctgcc tttggcgtcg ctacggcaac
     4261 ggtcatgctg ttggcccgag cagttggaga ggatgattgg aaaagagtcg ctagtttgag
     4321 taaacaaacc ttttggcttt ctctgttcct catgttgccc ctgtccttta gtatatatgt
     4381 cttgggtgta ccattaactc atctctatac gactgattct ctagcggtgg aggctagtgt
     4441 tctagtgaca ctgttttcac tacttggaac ccctatgacg acaggaacag tcatctatac
     4501 ggcagtctgg cagggattag gaaatgcacg cctccctttt tatgcgacaa gtataggcat
     4561 gtggtgtatc cgcattggaa caggatatct gctggggatt gtgcttggtt ggggcttgcc
     4621 tggtatttgg gcagggtctc tcttggataa tggttttcgc tggttatttc tacgctatcg
     4681 ttaccagcgc tatatgagct tgaaaggata ggaaatgcaa aaaacagctt ttatttggga
     4741 tttagacggg actttattgg actcttacga agcgatttta tcagggattg aggagacttt
     4801 tgctcagttt tctattcctt atgataagga gaaggtgaga gagtttatct tcaagtattc
     4861 ggtgcaagat ttgcttgtgc gggtggcaga agatagaaat ctggatgttg aggtgctaaa
     4921 tcaggtgcgt gcccagagtc tggctgagaa gaatgctcag gtagttttga tgccaggtgc
     4981 gcgtgaggtg ctagcttggg cagacgaatc aggaattcag cagtttatat atactcataa
     5041 ggggaacaac gcttttacca ttctcaagga cttgggggtg gaatcctatt ttacagagat
     5101 tttaaccagt cagagtgact ttgtgcggaa gccaagtcca gaagcggcta cctatctgct
     5161 agataagtat cagttgaatt ctgataatac ttattatata ggggatcgga ctctggatgt
     5221 ggaatttgcc cagaatagtg ggattcaaag tatcaacttt ttagagtcta cttatgaagg
     5281 gaatcacagg attcaagcgt tagcagatat ttcccgtatt tttgagacta agtgataaaa
     5341 agattgtgtc agttttgtga cagagaccta acaaactatt tcaagtaacc tagtttgtta
     5401 caaggaatag acagttctgt taaataggcc cgagagggct ttttttctac attttttgtg
     5461 ttatgataga caggtactca tttgaaagga atttgaaaga atgaagaaaa gaatgttatt
     5521 agcgtcaaca gtagccttgt catttgcccc agtattggca actcaagcag aagaagttct
     5581 ttggactgca cgtagtgttg agcaaatcca aaacgatttg actaaaacgg acaacaaaac
     5641 aagttatacc gtacagtatg gtgatacctt gagcactatt gcagaagcct tgggtgtaga
     5701 tgtcacagtg cttgcgaatc tgaacaaaat cactaatatg gacttgattt tcccagaaac
     5761 tgttttgaca acgactgtca atgaagcaga agaagtaaca gaagttgaaa tccaaacacc
     5821 tcaagcagac tctagtgaag aagtgacaac tgcgacagca gatttgacca ctaatcaagt
     5881 gatcgttgat gatcaaactg ttcaggttgc agacctttct caaccaattg cagaagctcc
     5941 aaaagaagta gcatcaagtt cagaagttac aaagacagtg attgcttctg aagaagtggc
     6001 accatctacg ggcacttctg tcccagagga gcaaacggcc gaaacaagca gtgcagttgc
     6061 agaagaagct cctcaggaaa cgactccagc tgagaagcag gaaacacaag caagccctca
     6121 agctgcatca gcagtggaag taactacaac aagttcagaa gcaaaagaag tagcatcatc
     6181 aaatggagct acagcagcag tttctactta tcaaccagaa gagacgaaaa taatttcaac
     6241 aacttacgag gctccagctg cgcccgatta tgctggactt gcagtagcaa aatctgaaaa
     6301 tgcaggtctt caaccacaaa cagctgcctt taaagaagaa attgctaact tgtttggcat
     6361 tacatccttt agtggttatc gtccaggaga cagtggagat cacggaaaag gtttggctat
     6421 cgactttatg gtaccagaac gttcagaatt aggggataag attgcggaat atgctattca
     6481 aaatatggcc agccgtggca ttagttacat catctggaaa caacgtttct atgctccatt
     6541 cgatagcaaa tatgggccag ctaacacttg gaacccaatg ccagaccgtg gtagtgtgac
     6601 agaaaatcac tatgatcacg ttcacgtttc aatgaatgga taaacccgac ttgataacat
     6661 cattttgacg aatgagatct agctttcgtg atggcaagcg attctcgttc gttttttctt
     6721 tgtcatactc ttcgaaaatc tcttcaaacc acgtcagttt tatctgaaac ttcaaagctg
     6781 tgctttgagc aacctgcgac tagcttccta gtttgctttt tgattttcat tgagtatcaa
     6841 tttgaatgga aaatggaaag ttatcatctt gtaatgagtt aagcaacatt cttgcaatct
     6901 attttacttt atatcacaat taattagtca aatattgata aatcaataaa aagagagggg
     6961 aagaaatgct agagattcaa gatttactgt atcaactccg cttgtctgag caagcgagta
     7021 cgcaattgtt tgaaaaaagg cttgggatta gtttgacacg gtatcagatt ttactgtttt
     7081 tgctggagca ttctccttgt aaccaaatgg cgattcagga gcgtttgaaa attgatcagg
     7141 ctgctttgac acggcatttc aagattttgg aaacggaagg tttggtggag cgtcatcgta
     7201 atcctgaaaa tcagcgggaa gtgttggtag aggctgcgaa gtatgccaag gagcagttag
     7261 tggtgaatcc ccctctgcaa catatcaagg ttaaggaaga gatggaaagt atcttaacag
     7321 agtttgagag aacagaactc agccgtttat taaataaatt ggttttgggt attgaaaata
     7381 tagaaattta aggagaaata gatgtcaatt attacaatta ttttaacaac gatcgttgct
     7441 ttggagcatt tttacatttt ttatttggaa agtattgcta cgcgatcaga tgcgactagt
     7501 cgtgtattta atatggaaaa ggaagaattg gctcatccgt cagtaagttc attgttcaaa
     7561 aatcaaggga tttataaggc tctgctagga gtctttctct ggtatggcat ttatttctca
     7621 cagaatttag aaattgtgac tatttttgtc ttatttgtga ttggtgctgc gacttacggc
     7681 tctttaacag cggataaaaa aattattttg aagcaaggtg gatcagctat tttggccttg
     7741 attagtattt tactctttaa aatacacttg aaggtcgatt ctaatctcgc taatcctttt
     7801 taatccagaa taagggaaat atgttatact tgtttttaag aaaaaagtct cattgaattg
     7861 gttttgagga gttagaaatg aaagtattag tgacaggttt tgagcccttt ggaggggaaa
     7921 agggcaatcc aactttggag gccattaaag gtttaccagc tgaaatccat ggtgctgagg
     7981 tccgttggct agaggtgccg acagtttttc acaaatctgc tcaagtattg gaagaagaga
     8041 tgaatcgtta tcaacctgac tttgtccttt gtattgggca agctggtgga agaactagtg
     8101 tgacacctga acgagtggcc attaatcaag acgatgcacg catttctgat aacgaagata
     8161 atcaaccgat tgaccgtccc attcgcccag atggtgcttc ggcctacttt agtagtttgc
     8221 cgattaaagc gatggttcaa gctataaaaa aagagggctt accggcctct gtttccaata
     8281 cggcagggac ttttgtctgc agccatttga tgtatcaggc tctctatttg gtagaaaaga
     8341 aatttccata tgttaaggca ggttttatgc atattcctta tatgatggaa caggtggtga
     8401 acagaccgac tactccaact atgagtttag tggatattcg gcgagggata gaagcagcaa
     8461 tcggcgctat gatagaacat ggagatcagg aactcaagtt ggtaggcgga gaaactcatt
     8521 gatagaaaaa agcttgaggg gaaaaacctt caagcttttg gacgttttcg agccaatact
     8581 gctcggtaaa acataatttt agtgcattgg atataaggta ggagtgaaaa actagcaatg
     8641 ccaaaggtaa tccaattgag gaagtaccaa ggaagaagct gtaaatctag gacaaagtgc
     8701 tggaacttgt agcccttcat aaaggaacgg ctagttttta ggattcgtct tggtgggacc
     8761 tgtcctaggt ctagactata acagagaaga aattccacct gtgaataggc ataatactgt
     8821 ggaatataga ggatatttcc tacaatgatc aagatgagac ttgcaagaaa gtagagtcca
     8881 aagaccatga ggaaacgctc ggtttcaact gatgagagat ctagatttgg aaactcagga
     8941 tgtagggtga cgaatttttt ggctaaaaag ctactataaa agaggagata aatcccaagt
     9001 aaattaggga tactccataa aaagagatag aaacgtttga gaagtagggt caaaaaggtt
     9061 tgagaaaagc gctcctcatc aaagagagct aggctgtttt ttacagatgg ctccgtttta
     9121 gaatctttca tgagtgtcag tgttgcatag acggaactgg tcaaaagaat agtcccgata
     9181 aaggagacta gtagaggaaa gaggtaggct tgaagtattt ggccaagtat gctgaaaaat
     9241 ggctgttcta aaacagtccc gtggatccga gataagggat taagaaaact agataagatg
     9301 accagcatac tgggaaggat atagaggaga aagagacggg gggtgtcagc ctgaaaatgt
     9361 tttgactcct gacgaattgt ttttaaatca atttttggat agttcattct cttattatac
     9421 catagttctt atacatagtt cgtgacagtt cctacttttt ttgataaaat catacagtgt
     9481 gtccttgggc acactgtatg aactgggact gtctttccca gcttcggagg taaaaaatgt
     9541 cagattcacc aatcaaatat cgtttgatta agaaagaaaa acacacagga gctcgtctag
     9601 gagaaatcat cactccccac ggtacctttc cgacacctat gtttatgcca gttgggacac
     9661 aagccactgt caaaactcag tcacctgaag aattgaagga gatgggttcg ggaattatcc
     9721 tatcaaacac ttatcatctc tggcttcgcc ctggagatga actcattgca cgcgctggtg
     9781 gtctccacaa gttcatgaat tgggaccagc ctatcttgac agatagtggt ggttttcagg
     9841 tttattcttt agcagatagc cgtaatatca cagaagaagg agtaaccttt aaaaatcatc
     9901 taaatggttc taagatgttc ctatccccag aaaaagccat ctctattcag aataatctgg
     9961 gttcagacat catgatgtcc tttgatgaat gtcctcagtt ttatcaacct tatgactacg
    10021 ttaagaaatc gatcgagcgt accagccgtt gggctgagcg tggtttgaag gctcaccgtc
    10081 gtccacatga ccaaggtttg tttggaattg tgcaaggtgc aggatttgaa gaccttcgcc
    10141 gccaatcagc tcatgatctt gtcagcatgg atttctcagg ctactctatc ggtggtttgg
    10201 cagtgggaga aacccatgaa gagatgaatg cggtcttgga ctttacaact caactgctgc
    10261 ctgaaaataa acctcgttat ctgatgggtg tgggagcgcc agatagcttg atcgatgggg
    10321 tcattcgtgg ggtggatatg tttgactgtg tcttaccgac tcgaattgct cgtaacggga
    10381 cttgtatgac cagtcaagga cgtttggttg tgaaaaatgc ccagtttgct gaggacttta
    10441 cgccactgga tcctgagtgt gactgctaca catgtaataa ctatacacgc gcttaccttc
    10501 gtcacctgct caaggctgat gaaacctttg gtatccgctt gactagctac cacaatcttt
    10561 acttcttgct taacctgatg aagcaagtgc gacaagccat catggatgac aatctcttgg
    10621 aattccgtga gtattttgtg gaaaaatatg gctataataa gtcaggacgc aatttctaaa
    10681 acggaataga tataagctaa aaatcctaag ttttctcttg ggatttttct tctttttttg
    10741 atagaataaa gtgtataatg aaagggagaa taaactcgta tgcgcattaa atggttttcc
    10801 ttgattagga ttacaggttt actactggta ctcttgtatc atttctttca gaccatcttt
    10861 cctggaggat ttttcggggt agatgtcttt ttcacatttt caggtttcct gattacggct
    10921 ctactcatcg aagaattttc taaaaatcat gagattgact tgataggatt ttttaggaga
    10981 cgcttttatc ggattgtgcc acctgtggtt ttgatggtct tggtgaccat gccctttacc
    11041 tttctagttc ggcaagatta tgtggctgga attgggggtc agattgcggg tgtcttaggc
    11101 tttatgacca acttctatga acttctaaca ggtgggaatt atgaatctca gttcattcca
    11161 catttgtttg ttcataattg gagcttggct gttgaggttc actactatat tctatgggga
    11221 ttggcagttt ggttcttatc caagcagtct agatcaaatg gtcagttgag agggatggtc
    11281 tttctcttat ctgctactgc cttcttgatt agcttcttct ccatgtttat cggtagtttt
    11341 ctagtgacct cttattcttc tgtttatttc tccagtttaa ctcatgtcta tccattcttt
    11401 ttgggaagta tcctagcaac gattgtaggc gttcgtcaga cgacttccct agttaagcaa
    11461 ttggataaaa tctgggattt acgcaagacc cttttagttt ttgcaggagg ttttggcttc
    11521 ttactcattt tgaccttctt cgtcaaattt acctatctct ttgcctatct tattggcttc
    11581 ttgcttgcca gtcttgcagc ccttgctatg attctggcgg cgcgtgtctt acatgaaaag
    11641 acacctaacg tgcaggagcc aaagatgatt agctttttag cagatactag ctatgcagtt
    11701 tatctcttcc attggccttt ctatatcatt ttctcacagt tgacatcaaa tcttcttgct
    11761 gtattactga ctctgatttg ttcttatggc tttgccagtc tttcatttta tgtgttggaa
    11821 ccttggattg caggaaagaa cacacctgtt ttacaaactc ttcgtcccct gccttatatt
    11881 cacgcaattc ttgcaacaag tacaggaatc ttggttttca ttgttttctt agtgacttta
    11941 ttggcaccac aagtgggagc gtttgagaca gacttaactg tcaatggctt gaagcaagct
    12001 gctagtaata ttgcccaaac aaaagtgatg gcagaacgag cagaagctga tagtttgggg
    12061 attgctgatg gtactatgtt aattggtgat tcagtggctt taagggcaaa tacagccctg
    12121 cagacagctc ttcctggagc acaaattaac gcgcaggtca gcagaacaac caagactgcc
    12181 aatgaaatca tgctaaacaa tagccagaat aaatttttac ctaagatggt ggtcattgcg
    12241 actggggtaa ataatcctga aaattacaag gaagactggg acagtattgt aaaaaatctt
    12301 cctaagggac accatatgat tttagtcact ccttatgagg gggataagac aaaagagacc
    12361 tatgccatcg ttgagaaggc tgctgcctat atgagagaat tggcagagaa gacaccttat
    12421 atcacagttg ctgattggaa tcaagttgcg aaagagcatc cagaaatttg ggcaggaaca
    12481 gaccaagtcc atttcggaag tgacactagc actattgaag caggagcaaa attgtatgca
    12541 gagaccattg ccacagcctt gcaaacagct caagacaagc cggttaaatc aaaataactt
    12601 gtattaaaaa agagaagagt tggagaaatc cagctctttt aaaatatctc caaaaaatag
    12661 gtctatacca tttacaaata aaaaagaaag gtttataatg taattgacat aataaattgt
    12721 agaatcaatc ttttaaggag gttaacatta tgcctaacta tattaaagcg gatcagtttt
    12781 tctacccaca cggagttcgt cgaggtggtt acttggaact tgtggacggc aagtttggga
    12841 aacatgtaga gcagattcct gaaggggctg aggtgattga ctatacaggt tatagcattg
    12901 ccccaggtct tgtggatact catattcatg gatatgcagg tgtagatgtg atggacaaca
    12961 acattgaagg tacattgcat actatgagtg aaggacttct tagtaccggt gttaccagtt
    13021 tcttacccac aactttaaca gccacttatg agcaattgct tgcagtcact gaaaatcttg
    13081 gaaaccatta taaagaagca acaggtgcta agattcgtgg gatttattat gaaggtccat
    13141 atttcacaga aacttttaag ggggcacaaa atccaactta tatgagagac ccgggtgttg
    13201 aggagtttca ttcttggcaa aaagcggcaa atggcttgct taataaaatt gcccttgcac
    13261 cagaacgtga tggggtggaa gactttgttc gtacagttac gggcgaaggt gtgacggttg
    13321 ctcttggaca ttcaaacgcg acttttgatg aagccaaaaa agcagtcgat gctggagcga
    13381 gtgtttgggt gcatgcctac aatggaatgc gtgggttgac tcaccgtgaa ttgggtatgg
    13441 ttggagccat gtaccaattg ccacatacct atgcagagtt gatctgtgat ggtcaccacg
    13501 tagatccaaa ggcttgcgaa attcttatca aacaaaaagg aacagaaaac atcgctctta
    13561 tcacagactg tatgacagct gggggattgg aagacggaga ttatatgttg ggagaattcc
    13621 cagttgtcgt tgcaaatgga actgcacgcc tcaaatcgac aggtaacttg gcaggttcta
    13681 tcctcaaact caaagatggt ttgaagaatg tggtcgaatg gggaattgcg aatccgcatg
    13741 aagcagtcat gatggccagc ttcaacccag ctaaatccgt tcacatcgat gacgtctgtg
    13801 gccaaatccg tgaaggctac gacgctgact tcatcgtatt agataaagat ttggaattgg
    13861 tagcaaccta tctagatggc gtaaaacgtt atcaagcata agagagaagg cagaagttag
    13921 agactagctt ctgctttttt atacagggta ctttactggt aaataaaaag ttaaaaaaat
    13981 cacaaaaaaa gcttgaagaa acaaagaaaa aggcttacaa ttgaactata aatattacaa
    14041 ataaaaaaac ggaggagtgc tttatgaaag cctatactta tgttaaacca ggacttgctt
    14101 cttttgttga tgtagacaaa ccagttattc gcaagccaac agacgctatt gtgcgtattg
    14161 taaaaaccac tatttgtgga acagacctcc atattatcaa aggggatgtt cctacttgcc
    14221 aaagtggtac cattcttggc cacgaaggga ttgggattgt tgaagaagtt ggggaaggag
    14281 tttccaactt caaaaaaggt gacaaggtct tgatttcttg cgtctgtgcc tgtggtaaat
    14341 gctactactg taaaaaagga atttatgctc actgtgaaga cgaagggggc tggattttcg
    14401 gtcacttgat tgatggtatg caggctgaat atctacgtgt ccctcatgca gataatactc
    14461 tttaccatac tccagaagac ttgtcagatg aagctttggt tatgctgtca gacattctgc
    14521 ctactggata tgaaattggt gtcttaaaag ggaaagtaga acctggttgc agcgtagcca
    14581 ttattggttc aggtccagtt ggattggctg ctcttttaac agcccaattc tattcaccag
    14641 ctaaattgat tatggtagac ctagacgata accgcttgga aactgcccta tcattcggtg
    14701 cgactcataa ggttaattct tcagaccctg aaaaagccat taaagaaatt tatgatttga
    14761 cagatggtcg tggtgtggat gtcgctatcg aagctgttgg tattcctgca acatttgatt
    14821 tctgtcaaaa gattatcggt gtagacggaa cggttgccaa ctgtggtgtg catggtaaac
    14881 cagttgaatt cgatttagat aaactttgga ttcgcaacat caatgtaaca actggtttgg
    14941 tatctacaaa tacgactcca caattgttga aagcgcttga aagtcataag attgaaccag
    15001 aaaaattggt aactcactat ttcaaactca gtgaaattga aaaagcctac gaagtcttca
    15061 gtaaggcagc agaccaccat gccattaagg tcattatcga aaacgatatc tcagaagcct
    15121 aagtagtaaa aatatttttg tacataagta aatagaaatt cagtcatcca tcagatggct
    15181 ggatttttta tcaaaaaatt aagaaatgag catatttctt tccttgtctg gcggaattgg
    15241 ttataatata cggtacaaag gaatgaatga atatgtatcg tgttatagaa atgtacggag
    15301 attttgaacc gtggtggttc ttagaaggtt gggaagaaga tattgtagca agtagaaaat
    15361 ttgaccagta ttatgatgct ctcaaatact acaaaacttg ctggtttaga ttggaacaag
    15421 aatcgcctct ttataaaagt agaagcgact tgatgaccat tttttgggac ccggaagacc
    15481 aacgctggtg tgatgaatgt gatgagtatt tacaacaata ccattctttg gctcttttgc
    15541 aggatgagca ggttatccca gacgaaaaac tacgctcagg ctatgaaaaa caaaccagtc
    15601 aggaaaggaa tcgttcttgc cgtatgaaat taaaatagag aaaagtaact tttttggagt
    15661 tgcttttttt atttttctaa ctctttgcga atagtatagg tgaggaggta agtatggttc
    15721 aagaaattgc acaagaaatc attcgttcag ctcggaaaaa agggacgcag gatatctatt
    15781 ttgtccctaa gttagacgcc tatgagcttc atatgagggt aggagacgag cgctgtaaaa
    15841 ttggtagcta tgattttgaa aagtttgcag ccgttatcag tcactttaag tttgtggcgg
    15901 gtatgaatgt gggagaaaaa agacgtagtc aactgggttc ctgtgattat gcctatgacc
    15961 agaagatagc gtctctacgt ttatctactg taggcgatta tcgggggcat gagagtttgg
    16021 ttatccgttt gttgcacgat gaggagcagg acctgcattt ttggtttcag gatattgaag
    16081 aattaggcaa gcagtacagg caacgggggc tctatctttt tgctggtccg gttgggagtg
    16141 gtaagacgac cttgatgcat gaattgtcca agtcactctt taaaggacag caagttatgt
    16201 ccatcgaaga tcctgtcgaa atcaagcagg acgacatgct tcagttgcag ttgaacgaag
    16261 caatcggcct aacctatgaa aatctaatca aactttcctt gcgtcatcga ccagatctct
    16321 tgattatcgg agaaattcgt gacagcgaga cggcgcgtgc agtggtcaga gctagtttga
    16381 caggtgcgac agtcttttca accattcatg ctaagagtat ccgaggtgtt tatgagcgtc
    16441 tgctggagtt gggtgtgagt gaagaagaat tggcagttgt tttgcaagga gtctgctacc
    16501 agagattaat cgggggagga ggaatcgttg actttgcaaa cagagattat caagaacacc
    16561 aagcagccaa gtggaatgag caaattgacc agcttcttaa agatggacat atcacaagtc
    16621 ttcaggctga gacggaaaaa attagctaca gctaagcaaa aaaatatcat caccctattt
    16681 aacaatctct tttctagcgg ttttcatctg gtggagacca tctccttttt agataggagt
    16741 gctttgttgg acaagcagtg tgtaacccag atgcgtgtgg gcttgtctca ggggaaatca
    16801 ttctcagaaa tgatggaaag tttgggatgt tcaagtgcta ttgtcactca gttatcccta
    16861 gctgaagttc atggcaatct ccacctgagt ttgggaaaga tagaagaata tctggacaat
    16921 ctggccaagg tcaagaaaaa attaattgaa gtagcgacct atcctttgat tttgctgttt
    16981 tttcttctct taattatgct ggggctacgg aattacctgc tcccacaact ggatagtagc
    17041 aatattgcca cccgaattat cggtaatctg ccacaaattt ttctaggcat ggtagggctt
    17101 gtttccgtgc ttgccctttt agcactaact ttttataaaa gaagttctaa gatgagtgtt
    17161 ttttctatct tagcacgcct tccctttatt ggaatctttg tgcagaccta cttgacagcc
    17221 tattatgcac gtgaatgggg gaatatgatt tcacagggaa tggagctgac gcagattttt
    17281 caaatgatgc aggaacaagg ttcccagctc tttaaagaaa tcggtcaaga tctggctcaa
    17341 accctgaaaa atggccgtga attttctcag acgataggaa cctatccttt ctttaggaag
    17401 gaattgagtc tcatcataga gtatggggaa gttaagtcca agctgggtag tgagttggaa
    17461 atctatgctg aaaaaacttg ggaagccttt tttacccgag tcaaccgcac catgaatttg
    17521 gtgcagccac tggtttttat ctttgtggca ctgattatcg ttttacttta tgcggcaatg
    17581 ctcatgccca tgtatcaaaa tatggaggta aatttttaaa atgaaaaaaa tgatgacatt
    17641 cttgaaaaaa tctaaggtta aagcttttac attggtggag atgttggtgg tcttgctgat
    17701 tatcagcgtg cttttcttgc tctttgtacc taatctgacc aagcaaaaag aggcagtcaa
    17761 tgacaaagga aaagcagctg ttgttaaggt ggtggaaagc caggcagaac tttatagctt
    17821 ggaaaagaat gaagatgcta gcctaagcaa gttacaagca gatgggcgaa tcacggaaga
    17881 acaggctaaa gcttataaag aataccatga taaaaatgga gtagcaaatc gtaaagtcaa
    17941 tgattaaggc ctttaccatg ctggaaagtc tcttggcttt gagtcttgtg agtatccttg
    18001 ccttgggctt gtccggctct gttcagtcca cttttgcggc agtagaggaa cagattttct
    18061 ttatggagtt tgaagaactc tatcgggaaa cccaaaaacg cagtgtagcc agtcagcaaa
    18121 agactagtct gaacttagat gggcagacga ttagcaatgg cagtcaaaag ttgccagtcc
    18181 ctaaaggaat tcaggcccca tcaggccaaa gtattacatt tgaccgtgct gggggcaatt
    18241 cgtccctggc taaggttgaa tttcagacca gtaaaggagc gattcgctat caattatatc
    18301 taggaaatgg aaaaattaaa cgcattaagg aaacaaaaaa ttagggcagt gattttactg
    18361 gaagcagtag tcgctctagc tatctttgcc agcattgcga ccctcctttt gggacaaatt
    18421 caaaaaaata ggcaagagga agcaaaaatc ttgcaaaagg aagaagtctt gagggtagct
    18481 aagatggcct tgcagacagg tcaaaatcag gtaaacataa acggagttga gattcaggtg
    18541 ttttctagcg aaaagggatt ggaggtctac catggttcag aacagttgtt ggcaatcaaa
    18601 gagccataag gtcaaggctt ttaccttgtt agaatccctg cttgccctgc tcgtcatcag
    18661 tggaggctta ctcctttttc aagctatgag tcagctcctc atttcagaag ttcgctacca
    18721 gcaacaaagc gagcaaaagg agtggctctt gtttgtggat caacttgagg cagaattaga
    18781 ccgttcgcag ttcgaaaaag tggaaggcaa tcgtttctat atgaagcaag atggcaagga
    18841 catcgccatc ggtaagtcaa agtcagacga ttttcgtaaa accgatgcta gtggacgggg
    18901 gtatcagcct atggtttatg gcctcaaatc agctcagatt acagaggaca atcaactggt
    18961 tcattttcgt ttccagtttc aaaaaggctt agaaagggag ttcatctatc gtgtggaaaa
    19021 agaagaaagt taaggcaggt gttctcctct atgcagtcac catggcagct atctttagtc
    19081 ttttgttgca attttacttg aaccgacaag tcgcccacta tcaagactat gctttgaata
    19141 aagaaaaatt ggttgctttt gccatggcta aacgaaccaa ggataaagcc gagcaagaaa
    19201 gtggggaaca ggtctttaat ctaggtcagg taagctatca aaacaagaaa acaagcttgg
    19261 tgacgactgt tcgtacggat aagagtcaat atgagtttct gtttccttca gtcaaaatca
    19321 aagaagagaa aagagataaa aaggaagagg tagcgactga ttcaagcgaa aaagcggaga
    19381 agaaaaaatc agaagagaag cctgaaaaga aagagaattc ctagtcaatt caactataat
    19441 gcgttgaatc cagaatagtc cactgtagtt tctagaaaat tgctggaaat ggatgttaag
    19501 ctccaattca tttgtttata tcttatttca gtttactata ctttgtgcta aactaaagat
    19561 atgaaacatg attttaacca caaagcagaa actttcgatt cccctaaaaa tatcttcctc
    19621 gcaaacttgg tatgtcaagc agtcgagaaa cagattgata ttttatcaga caaagaaatt
    19681 ttagatttcg gtggtggcac gggtctatta gccttgcccc tagccaagca ggctaagtca
    19741 gttactcttg tagacatttc tgagaaaatg ttggagcaag ctcgtttgaa agcggagcag
    19801 caagcaatca agaatatcca gtttttggag caagatttac cgaaaaatcc cttggagaaa
    19861 gagtttgatt gccttgctgt tagtcgggtt cttcatcata tgcctgattt ggatgcggct
    19921 ctctcactgt ttcatcaaca tttgaaggaa gatgggaaac tcatcattgc tgattttacc
    19981 aagacagaag ctaatcatca tggatttgat ttagctgaac tggaaaacaa gctaattgag
    20041 catggttttt catctgtgaa tagtcagatt ctctatagcg ctgaagacct gtttcaagga
    20101 aattactcag aattcttttt aatagtagcc caaaaatcac tcgcctagtc agggagtgat
    20161 ttttctataa ggatggaaaa aagaagggaa atttgataag ataggaatat ggattttgaa
    20221 aaaattgaac aagcttatac ctatttacta gagaatgtcc aagtcatcca aagtgatttg
    20281 gcgaccaact tttatgacgc cttggtggag caaaacagca tctatctgga tggtgaaact
    20341 gagctaaacc aggtcaaaga caacaatcag gcccttaagc gtttagcact acgcaaagaa
    20401 gaatggctca agacctacca gtttctcttg atgaaggctg ggcaaacaga acccttgcag
    20461 gccaatcacc agtttacacc agatgccatt gctttgcttt tggtgtttat tgtggaagag
    20521 ttgtttaaag aggaggaaat tactatcctc gaaatgggtt ctgggatggg aattctaggc
    20581 gctactttct tgacctcgct tgataaaaag gtggattact tgggaatgga aatggatgat
    20641 ttgctgattg atctggcagc tagcatggca gatgtaattg gtttgcaggc tggctttgtc
    20701 caaggagatg ccgttcgtcc acaaatgctc aaagaaagcg atgtggtcat cagtgacttg
    20761 cctgttggct attatcctga tgatgccgtt gcgtcgcgcc atcaagttgc ttctagccaa
    20821 gaacatactt acgcccatca cttgctcatg gaacaagggc ttaagtacct caagtcagac
    20881 ggatacgcta tttttctagc tccgagtgat ttgttgacca gtcctcaaag tgatttgtta
    20941 aaagaatggc tgaaagaaga ggcgagtctg gttgctatga ttagtctgcc tgaaaatctc
    21001 tttgctaatg ccaaacaatc taagactatt tttatcttac agaagaaaaa tgaaatagca
    21061 gtagagcctt ttgtttatcc acttgctagc ttgcaagatg caagtgtttt aatgaaattt
    21121 aaagaaaatt ttcaaaaatg gactcaaggt actgaaatat aaaatagatt ttgttataat
    21181 agttgaaaac gcttaaaaag gggtatcatg ttatgacaaa aacaattgca atcaatgcag
    21241 gaagttcaag tttgaaatgg caattatact taatgccaga agaaaaagta ttggcgaaag
    21301 gtttgattga acgtatcggt ttgaaagatt caatttcaac tgtaaaattt gacggccgtt
    21361 ctgaacaaca aattttggat attgaaaatc atacacaagc cgttaaaatt ttattggatg
    21421 acttgattcg tttcgatatt atcaaggctt atgacgagat tacaggtgtt ggacatcgtg
    21481 ttgttgctgg tggagaatat ttcaaagaat caacagttgt tgagggagat gttttagaaa
    21541 aagttgaaga gttgagtttg ttggctcctc tacacaaccc ggccaatgca gcaggtgttc
    21601 gtgccttcaa ggaattgttg ccagacatta ccagtgtagt tgtttttgat acttccttcc
    21661 acacaagtat gccagagaaa gcttatcgct accctctacc aacaaaatat tacacagaaa
    21721 acaaggttcg taaatacggt gctcatggta caagtcacca gtttgtagca ggagaagctg
    21781 caaaactctt gggacgtcca ttagaagact tgaagttaat tacctgtcat attggtaacg
    21841 gaggctcaat tacagctgtg aaagccggca aatctgtaga cacttctatg gggttcactc
    21901 ctcttggtgg tattatgatg ggaacgcgta caggggatat tgatccagct atcattcctt
    21961 atttaatgca atatacagag gattttaaca caccagaaga tatcagtcgt gttcttaacc
    22021 gtgaatcagg tcttttggga gtttctgcta attctagcga tatgcgcgat atagaagcag
    22081 ctgtagcaga agggaatcac gaggctagct tggcttatga aatgtatgtt gaccgtatcc
    22141 aaaaacatat cggtcagtac cttgcagtgc taaatggagc agatgccatt gttttcacag
    22201 caggtgtcgg tgaaaatgca gagagtttcc gtcgtgatgt aatctcaggg atttcgtggt
    22261 ttggttgtga tgttgatgat gaaaagaatg tctttggcgt tacaggagac atctcaacag
    22321 aggcagctaa aatccgtgtc ttggttattc caacagatga agaattagtc attgcccgtg
    22381 acgttgaacg cttgaaaaaa taagtgaaac taaaaaaata ttcaatacaa ggagttggga
    22441 aagttatttt tccagcttct ttttctgatg aaattgtcca aaaccttgct atgattggct
    22501 tttttgaaaa atatggtata atagtagtaa tttaatagat ggagttgagt tttgaagaaa
    22561 aactttcgtg taaaaagaga gaaagatttt aaggcgattt tcaaggaggg gacaagtttt
    22621 gctaatcgca aatttgtggt ctaccaatta gaaaaccaga aaaaccattt tcgagtaggt
    22681 ctatcagtta gcaaaaaact ggggaatgcc gtcactagaa atcaaattaa gcgacggatt
    22741 cggcatatta tccagaatgc aaaagggagt ctggtagaag atgtcgactt tgttgtcatt
    22801 gctcgaaaag gagtcgaaac cttgggatac gcagagatgg agaaaaatct actccatgta
    22861 ttaaaattat caaagattta ccgggaagga aatgggagtg aaaaagaaac taaagttgac
    22921 tagtttgcta ggactgtctc tgttaatcat gacagcctgt gcgactaatg gggtaactag
    22981 cgatattaca gccgaatcgg ctgatttttg gagtaaattg gtttacttct ttgcggaaat
    23041 cattcgcttt ttatcgtttg atattagtat cggagtgggg attattctct ttacggtctt
    23101 gattcgtaca gtcctcttgc cagtctttca ggtgcaaatg gtggcttcta ggaaaatgca
    23161 ggaagctcag ccacgcatta aggcgcttcg agaacaatat ccaggtcgag atatggaaag
    23221 cagaaccaaa ctagagcagg aaatgcgtaa agtatttaaa gaaatgggtg tcagacagtc
    23281 agactctctt tggccgattt tgattcagat gccggttatt ttggccttgt tccaagccct
    23341 atcaagagtt gactttttaa agacaggtca tttcttatgg attaaccttg gtagtgtgga
    23401 tacaaccctt gttcttccga ttttagcagc agtattcacc tttttaagta cttggttgtc
    23461 caacaaagct ttgtctgagc gaaatggcgc tacgactgcg atgatgtatg ggattccagt
    23521 cttgattttt atctttgcag tttatgcgcc aggtggagtc gccctatact ggacagtgtc
    23581 taatgcttat caagtcttgc aaacctattt cttgaataat ccattcaaga ttatcgcaga
    23641 gcgcgaggcc gtagtacagg cacaaaaaga tttggaaaat agaaaaagaa aagccaagaa
    23701 aaaggctcag aaaacgaaat aaataaggag gaatctggta atggtagtat ttacaggttc
    23761 aactgttgaa gaagcaatcc agaaaggatt gaaagaatta gatattccaa gaatgaaggc
    23821 tcatatcaaa gtcatttcta gggagaaaaa aggctttctt ggtctatttg gtaaaaaacc
    23881 agcccaagtg gatattgaag cgattagtga aacgactgtt gtcaaagcaa atcaacaggt
    23941 agtaaaaggc gttccgaaaa aaatcaatga tttgaacgag cctgtgaaga cggttagtga
    24001 agaaaccgtt gaccttggtc atgtggttga tgctattaaa aaaatagagg aagaaggtca
    24061 aggtatttct gatgaagtca aggctgaaat cttaaaacat gaaagacatg ccagcactat
    24121 cttagaagaa actggtcaca ttgagatttt aaatgaactt caaatcgagg aagcgatgag
    24181 ggaagaagca ggcgctgatg accttgaaac tgagcaagat caaactgaaa gtcaagaact
    24241 agaagacttg ggcttgaaag ttgaaacgaa ctttgatatt gaacaagtag ctacggaagt
    24301 aatggcttat gttcaaacga ttattgatga catggatgtt gaggctacac tttcaaatga
    24361 ttataaccgt cgtagcatca atctacaaat tgacaccaac gaaccaggtc gtattatcgg
    24421 ctaccatggt aaagtcttga aggccttgca actgttggct caaaattatc tttacaaccg
    24481 ctattccaga accttctacg ttacaatcaa tgtcaatgat tatgtcgaac accgtgcaga
    24541 agtcttgcag acctatgcgc aaaaattggc gactcgtgtt ttggaagaag ggcgcaatca
    24601 taaaacagat ccaatgtcaa atagcgaacg caagattatc catcgtatta tttcacgtat
    24661 ggatggcgtg actagttact ctgaaggtga tgagccaaat cgctatgttg ttgtagatac
    24721 agaataagta aaatcaggtt tatcctgatt ttttgctagt tagaggaggt taaactgatg
    24781 ttgaataaga taagagacta tttagacttt gctggtttgc agtaccgtaa tcctgataaa
    24841 gcgggagcag agcgagagaa gatgctggca ttccgccaca aaggacaaga ggctcgaaag
    24901 gcttttacag aactggccaa agcctttcaa gcaagccatc cagaatggca actccaacag
    24961 actagtcagt ggatgaatca ggcccagcgt ttgagaccac atttttgggt ttatctacag
    25021 agagacggac aagtgacaga acctatgata gccttgcgtt tgtatggaaa tccttctgat
    25081 tttggtattt ccttagaagt cagtttcatc gaacgtaaga aggatgagca aacactgggc
    25141 aagcaggcca aagttttaga aattccaacc gttaaaggga tttattatct aacctactct
    25201 aatggtcaaa gtcaacggtg ggaggcgaat gaagaaaagc gtcgtacttt acgcgagaag
    25261 gtgagaagtc aagaagttcg aaaagtttta gtgaaggtag atgttcctat gacagaaaat
    25321 tcgtctgaag aagaaatcgt agaaggctta ttgaagtctt attctaaaat tcttccctat
    25381 tatcaggtga ctagaggata acgtgtcagt caattattat aagattacag tccaagagtg
    25441 aacagtccgc tgtgtaattc ttggtctttt tgtttgcgct ttcgcattat ataataaact
    25501 tacaaaaaca attcaaaagg agaacaatta tggaagtcgt ttcaaatgtt ctaaattggt
    25561 tttctagcaa tattttgcag aatcccgcat ttttcgtagg tttattggtg ttgataggat
    25621 atgcactttt gaaaaaacct gcccatgacg ttttttcagg gtttgttaaa gcaacagtag
    25681 ggtatatgtt gcttaacgtg ggtgctggtg gtttggttac aacctttcgt ccaatcttag
    25741 cagctcttaa ctacaaattc caaattggtg cagcggttat cgacccttac tttggacttg
    25801 ctgcagcaaa caacaaaatt gcagcagagt ttccagattt tgttggaact gcaactacag
    25861 ctctattgat tggttttgga ataaatatct tgctcgtagc tcttcgaaag attacgaagg
    25921 taagaaccct ctttattact ggtcacatca tggtacaaca agctgcaaca gtatctctta
    25981 tggttctatt cttagtacca caattgcgca atgcttacgg tacagcagcg attggtatca
    26041 tctgtggact ttactgggca gttagttcaa atatgactgt tgaggcaact caacgcttga
    26101 ctggtggtgg cggatttgcg attggtcacc aacagcaatt tgcaatctgg tttgtagata
    26161 aagtagcagg acgctttggt aagaaagaag aaagtttaga caatcttaaa ttacctaagt
    26221 tcctctcaat cttccacgat acagttgttg catctgctac cttgatgctc gtattcttcg
    26281 gagccattct tttaatcttg ggtccagaca ttatgtctaa taaagaagtc atcacttcag
    26341 gaactctatt caatcctgct aaacaagatt tctttatgta cattatccaa acagccttta
    26401 ccttctcagt ttacttgttc gttttgatgc aaggtgtccg aatgttcgta tctgagttga
    26461 caaacgcctt ccaaggtatt tcaaacaaat tgttgccagg ttcattccca gcggttgacg
    26521 ttgcagcttc ttatggattt ggttctccaa atgctgtctt gtcaggattt acctttggtt
    26581 tgattggtca attgattata attgtcttgc tcatcgtctt taaaaatccg attcttatta
    26641 ttacaggatt tgtaccagtg ttctttgaca atgcagccat tgcggtctac gctgataaac
    26701 gcggcggatg gaaagcggct gttatccttt cctttatatc aggtgtcctt caagttgctc
    26761 taggagctct ttgtgtggcc cttctcgatt tggcagctta tggtggctac catggaaata
    26821 tcgactttga attcccatgg cttggatttg gatatatctt caaatacctt ggtattgttg
    26881 gttatgtact tgtgtgtctc ttcttgcttg ttattcctca acttcaattt gccaaagcaa
    26941 aagataaaga gaaatattac aacggtgaag ttcaagaaga agcttagtat ctagaaaagg
    27001 agaaataaaa tggttaaagt attagcagcg tgcggaaatg gaatgggttc atcaatggtt
    27061 atcaagatga aggttgaaaa tgctctccgt aagcttaatc aaagagattt tacagtcaat
    27121 tcatgcagtg tcggtgaagc taaaggttta gcagtaggat atgacatcgt aatcgcttct
    27181 cttcatttga ttcaagaatt ggaagggcga actaatggga agttaattgg gcttgataac
    27241 ttgatggatg ataaagaaat caccgaaaaa ctcagtcaag cactacagta aaaggttgga
    27301 gggggctgga cagaaactga gagttatcgt ttctgtcctt ctccctctta aataaaggag
    27361 gcagatatga atttaaaaca agctttaatt gacaatgact cgatccgact aggtttagag
    27421 gctaacaatt ggaaagaagc agtcaaggta gcagtagatc ccttaattga aagtggggca
    27481 attttgccag agtattacga tgctatcatt gaatcgactg aagagtatgg gccttactat
    27541 atcttgatgc caggtatggc tatgccccac gctagacctg aagctggtgt gcaaagtgat
    27601 gccttttcat tgattacctt acaaaatcct gttgtatttt cagatgggaa agaggtatct
    27661 gttttgttgg cactagcagc aacaagctca aaaattcaca caagtgtagc cattccacaa
    27721 attattgccc tgtttgaatt agaagattct attgcacgtt tacaggcttg ccagactaaa
    27781 gaagatgtct tggctatgat tgaagaatct aaggatagcc cttatctcga aggattggat
    27841 ttggaaagtt agaaagagga ataaagaaat gacaaaaaga atacctaatt tacaagttgc
    27901 attagaccat tcagacttgc aaggagcgat taaagcagct gtttctgttg gtcaggaagt
    27961 agatattatc gaagctggaa ctgtttgctt gcttcaagtt ggaagtgaac tggctgaagt
    28021 cttgcgtagc cttttcccag ataagattat tgtggcagac acaaaatgtg ctgatgctgg
    28081 tggaacagtt gctaaaaata atgcggttcg tggagcagac tggatgactt gtatctgttg
    28141 tgcaaccatc cctactatgg aagcagctct aaaggctatc aagactgaac gaggagaacg
    28201 aggcgaaatc cagatcgagc tttatggcga ttggactttt gaacaagctc agctttggct
    28261 agatgcaggt atctcacaag ctatttatca ccaatctcgt gatgctcttc ttgctggtga
    28321 aacttggggt gaaaaagacc ttaataaggt taaaaaactc attgacatgg gcttccgtgt
    28381 atctgtaaca ggtggtctag atgtagatac tctcaaactc tttgaaggtg ttgatgtctt
    28441 tacctttatc gcaggtcgtg gaattacaga ggctgcggat ccagcaggag cagcgcgtgc
    28501 cttcaaggat gaaatcaaac gaatttgggg gtaaatcatg gtacgtccaa ttggaattta
    28561 tgaaaaggca accccaacac actttacttg gctagaacgt ttaaattttg ccaaggagtt
    28621 aggctttgat tttgtcgaga tgtctattga cgaacgtgac gagcgtttag caagacttga
    28681 ctggagtaag gaagaacgct tggaagttgt caaagcaatc tatggaactg gtgttcgtat
    28741 tccttctatc tgtttttcag gccatcgtcg ctacccattg ggttcaaaag atccagttct
    28801 agaggaaaaa tctctagaac tcatgaaaaa atgtatcgaa ttagctcaag acttgggagt
    28861 tcgtacgatt caattagctg gttacgatgt ttactatgag gaaaagtcac cccagacacg
    28921 ccaacgtttt atcaaaaatt tgagaaaagc ctgtgactgg gctgaagaag ctcaggtggt
    28981 acttgctatt gaaattatgg atgatccttt catcaatagc atcgaaaaat atttggctat
    29041 agaaaaagag attgactctc ccttcctctt tgtatatcca gatattggta atgtgtctgc
    29101 atggcataat gatatctata gtgagtttta tcttggtcat catgccatcg cagctctcca
    29161 tctcaaggat acttatgcag tgacagaaag ttcaaggggc cagttccgag atgtaccttt
    29221 tgggcaaggt tgtgtcaaat gggaagaagc tttcgatatt ttaaaggaaa ccaattataa
    29281 tggacctttc ctaatcgaaa tgtggtctga aaattgtgaa acagtagaag aaacacgcgc
    29341 agccattcaa gaggcgcaag cttttctcta tccactcatt aagaaagcag gtttgatgta
    29401 agatgaatca agtaatcaat gctatgcgta aacgagtctg tgatgccaat caatcattgc
    29461 caaaacatgg acttgtcaaa tttacctggg ggaatgtatc tgaagtcaat cgcgaactcg
    29521 gtgtcattgt tatcaaacca tcaggcgtgg attatgacga attgacacct gaaaacatgg
    29581 tagtgactga tctagatggt aagatcctag aaggggattt aagaccatct tccgacctcc
    29641 caactcatgt gcaattatat aaggcttggt cagaaattgg tagtgtggtt cacacccatt
    29701 cgacagaagc tgttggttgg gctcaggcag gtcgtgatat tcctttctac ggaacaaccc
    29761 atgcagatta tttctacggt tcaatccctt gcgcccgtag tttgaccaag gacgaagtag
    29821 aagtggccta tgaaaaagat actggcctgg ttatcgtaga agaatttgaa catcgcggac
    29881 ttaacccggt tgaagtacca ggaattgttg tacgcaatca cggtccattc acctggggca
    29941 aaaatccaga gaatgctgtt tatcactctg tcgtactaga ggaagtatca aagatgaatc
    30001 gctttacaga acaaatcaat ccaagagttg gacctgctcc ccagtacata ctagaaaaac
    30061 actaccaacg taaacatgga ccaaatgctt attatggtca aaagtaagaa cgatgaagga
    30121 ggagaaaaag ataaatttag ctcctctttt tacatttgat ttttattgag agtaaagttg
    30181 gagttgaagt aattttgaaa gattttttag aaatagcgct tgatatatat atatatggta
    30241 aaataaaaag aattgctgtg atatcaatag atttggggga ttttttaata tggtactgga
    30301 taaggcaagt tgtgatttac ttcaatattt gatggatcaa gaaacgtcca aaacgattat
    30361 ggcgatttcg aaagatttga aagagtcaag aaggaaaatt tattatcaca ttgacaaaat
    30421 caatgctgct ctgggtgacg aggcgcttca catcattagt attccacgaa ttggtattca
    30481 cttaacggaa gagcagagag atgcttgttg taaactatta tcggaagtag attcgtacga
    30541 ttatatcatg agtgcgcatg aacgtatgat gataatgtta ttatggatag gtatttctaa
    30601 agaacgtatt acgattgaaa aattgataga gttaacagag gtatctagga atactgttct
    30661 caatgatttg aatagtattc gttatcaact aactttggaa caatatcagg tgaccttgca
    30721 agtgagcaag tcacagggat accaccttca tgcccaccct cttaataaaa ttcagtatct
    30781 tcaatcgctt ctatatcata tttttatgga agaaaatgcc acttttgtat ctattttaga
    30841 agataagatg aaagagaggt tagatgatga gtgtttgctt tctgttgaaa tgaaccaatt
    30901 ttttaaggaa caggttcctt tagttgaaca agatttaggg aagaaaataa accatcatga
    30961 aataactttt atgttgcagg ttctacctta tttgctgtta agctgtcata atgttgaaca
    31021 gtatcaagaa agacatcagg atatagagaa agaattttct ttgataagaa aaagaataga
    31081 gtatcaggtg tctaagaaat taggagaacg gttgtttcaa aagtttgaaa tttctttgtc
    31141 aggacttgaa gtttctcttg tagctgttct cctcctctcc tatcgtaaag atttggatat
    31201 tcatgcagaa agtgatgatt ttcggcaatt aaaacttgct ttagaagaat ttatctggta
    31261 ttttgaatca caaatccgaa tggagattga gaacaaggat gatttgttac gaaatttgat
    31321 gatccactgt aaagccttgt tatttagaaa gacttacggt attttttcta aaaatcctct
    31381 aacaaaacaa attcgatcca agtatggaga attattttta gtcactagaa aatctgcgga
    31441 aattttagaa ggagcatggt ttattcggct aacagacgat gatattgcct atttgacgat
    31501 tcatattgga ggatttttaa aatatacacc atcgtctcaa aaaaatatga aaaaagttta
    31561 tctcgtttgt gatgaaggtg ttgcggtttc gagacttttg ctgaaacaat gcaaacttta
    31621 ttttccaaat gagcaaattg acactgtatt tacaacagaa caatttaaga gtgtggaaga
    31681 tattgcacaa gttgatgtag tgattactac taatgatgat ttggatagca gatttccgat
    31741 tttaagggtt aatcctatcc ttgaagcaga agatattttg aaaatgctag actatcttaa
    31801 acacaatata tttcgtaata agagcaaaag tttcagtgaa aatctttcta gtcttatttc
    31861 gtcttatatt gtagacagca agttggctag taagttccaa gaagaggttc aaacacttat
    31921 aaatcaagaa atagtagttc aagctttttt ggaagatatt tgaaggacag tccaatgatg
    31981 aacacaaacc tgtgtttttc ttggtctttt ttagtgtttt gaagggtggt atactaatct
    32041 caaagataac aattatatcc aaaggaggca acatatgcca aacgtcaaag aaattacaag
    32101 agagtcatgg attttagcca ctttcccaga gtggggaaca tggttgaacg aagaaatcga
    32161 agaagaagtc gtacctgaag gcaactttgc catgtggtgg ctaggcaact gtggtacttg
    32221 gattaagaca ccagctggtg ctaacgttgt catggacctt tggtcaaacc gtggaaaatc
    32281 aaccaaaaaa gtgaaagata tggttcgtgg gcaccaaatg gcaaatatgg caggtgttcg
    32341 taagttgcaa ccaaacttgc gtgttcagcc aatggttatc gatccatttg ctatcaacga
    32401 actagactat tacttagttt cacacttcca cagtgatcat atcgacccat acacagctgc
    32461 agcaattctc aacaatccta agttagagca tgttaagttt atcggtcctt accactgtgg
    32521 acgaatctgg gaaggatggg gggttccaaa agaacgtatc atcgttgtta aaccaggtga
    32581 cactatcgaa ttaaaagata tgaagattca tgcagtagaa tcatttgacc gtacttgctt
    32641 ggtaactctc ccagtgaacg gtgctgatga gacaggcggt gaacttgctg gcttggctgt
    32701 tacagatgaa gaaatggctc aaaaggctgt taactatatc tttgaaacac caggtggaac
    32761 catctatcat ggtgcagatt ctcacttctc aaactatttt gcaaaacatg gtaaagactt
    32821 taaaattgat gttgctttga ataactatgg tgaaaatccg gtaggtatcc aagacaaaat
    32881 gacatctatc gaccttcttc gtatggcaga aaatctgcgt accaaagtca ttatcccagt
    32941 tcactatgat atctggtcta acttcatggc ttctactaat gagattctag aactttggaa
    33001 aatgcgaaaa gatcgcttgc aatacgattt ccatccattt atctgggaag ttggcggtaa
    33061 gtacacttat cctcaagatc aacacttagt agaataccat catccacgtg gttttgatga
    33121 ttgttttgaa caagactcta acattcaatt taaagctttg ctataatata aaaatattct
    33181 ttggaggtta tccgtatgtt gcatgatacg gataattttc atataatagt aaaatagaat
    33241 gtgtgattca ataatcacct caaatagaaa ggaaattcta tgtcaaatct atctgttaat
    33301 gcaattcgtt ttctaggtat tgacgccatt aataaagcca actcaggtca tccaggtgtg
    33361 gttatgggag cggctccgat ggcttacagc ctctttacaa aacaacttca tatcaatcca
    33421 gctcaaccaa attggattaa ccgcgaccgc tttattcttt cagcaggtca tggttcaatg
    33481 ctcctttatg ctcttcttca cctttctggt tttgaagatg tcagcatgga tgagattaag
    33541 agcttccgtc aatggggttc aaaaacacca ggtcacccag aatttggtca tacggcaggg
    33601 attgatgcta cgacaggtcc tctagggcaa gggatttcaa ctgctactgg ttttgcccaa
    33661 gcagaacgtt tcttggcagc caaatataac cgtgaaggct acaatatctt tgaccactat
    33721 acttacgtta tctgtggaga cggagacttg atggaaggtg tctcaagcga ggcagcttca
    33781 tacgcaggtt tgcaaaaact tgataagttg gttgttcttt atgattcaaa tgatatcaac
    33841 ttggatggtg agacaaagga ttcctttaca gaaagtgttc gtgaccgtta caatgcctac
    33901 ggttggcata ctgccttggt tgaaaatgga acagacttgg aagccatcca tgctgctatc
    33961 gaaacagcaa aagcttcagg caagccatct ttgattgaag tgaagacggt tattggatat
    34021 ggttctccaa acaaacaagg aactaatgct gtacacggcg cccctcttgg agcagatgaa
    34081 actgcatcaa ctcgccaagc cctcggttgg gactacgaac catttgaaat tccagaacaa
    34141 gtatatgctg atttcaaaga acatgttgca gaccgtggcg catcagctta tcaagcttgg
    34201 actaaattag ttgcagatta taaagaagct catccagaac tggctgcaga agtagaagcc
    34261 atcatcgacg gacgtgatcc agtcgaagtg actccagcag acttcccagc tttagaaaat
    34321 ggtttttctc aagcaactcg taattcaagt caagatgcct tgaatgttgt ggcagctaaa
    34381 ttaccaacct tcctaggtgg atcagctgac cttgctcact caaacatgac ttatatcaag
    34441 acggatggac ttcaagacga taccaatcgc ttgaatcgta acattcagtt tggtgttcgt
    34501 gaatttgcaa tgggaacaat cttgaacggg atggcccttc atggtggact tcgtgtatac
    34561 ggtggaactt tcttcgtctt ctctgactat gtgaaggcag ctgtccgctt gtcagcctta
    34621 caaggacttc ctgtgactta tgtctttacc catgattcaa tcgcagttgg ggaagatggt
    34681 ccgactcacg aaccagttga gcatttagca ggtcttcgtg ctatgccaaa tctaaatgtt
    34741 ttccgtccag cagatgcgcg tgaaacgcaa gcagcttggt accttgcagt gacaagtgag
    34801 aaaacaccaa ctgcccttgt cttgacacgt caaaacttga ctgttgaaga tggaacagac
    34861 ttcgacaagg ttgctaaagg tgcttatgtt gtatatgaaa atgcagccga ctttgatacc
    34921 atcttgattg cgacaggttc agaggttaat cttgctgtct cagctgctaa agaattggct
    34981 agtcaaggcg aaaaaatccg cgtagtcagc atgccatcta cagatgtctt tgataaacaa
    35041 gatgcagctt acaaggaaga aattcttcca aatgcagtcc gccgtcgtgt tgcagtcgaa
    35101 atgggtgcaa gtcaaaactg gtacaaatat gttggtctcg atggtgccgt tctaggtatt
    35161 gataccttcg gagcctctgc cccagcacca aaagtattgg cagaatatgg ctttactgtc
    35221 gaaaatcttg taaaagttgt tcgaaatttg aaataatcct aaaaatcagg gcgtaagctc
    35281 tggtttttct taccagaaaa gtaaggtaca atcttgtaaa agtagctgaa atttgatata
    35341 gtagtcctat gtaaaagaca aaggagaaaa caatgaatcc aaatattact tttttaatca
    35401 tgcttgtagg tatgatggcc ttgatgttct ttatgcaacg ttctcaaaag aaacaagctc
    35461 aaaagcgtat ggaaagctta aataaactac aaaaaggcta tgaagtgatt acaatcggtg
    35521 gactttatgg aacagtcgat gaagtagata cggagaaggg aacaatagtt cttgacgtag
    35581 atggagttta cttgactttt gaactagctg ctatcaagac agtattaccg ctgaaagaaa
    35641 cagcttcact agaaggcgca attgaaaaat aagacgggat cacgaactcc cgttttctat
    35701 aaaagaaagg aaatgggatg aaaaaattag tctttgtctg tctgggaaat atttgccgta
    35761 gccctatggc cgagtttgtt atgaaatcaa tgacagataa ctacgaaatc caaagtcgag
    35821 caacttcctc ttgggaacat ggcaatccga ttcataaggg gactcaggga atttttcaag
    35881 agtatgagat tccttatgac aagaacaaga catcgcttca gattagtaag gaagattttg
    35941 aagcctttga ttatattatc ggaatggacg cttcaaatat ttctgactta cgtcagatgt
    36001 gtccagtaga ctgtcaagat aagatttact cattttcatc tgaaagtgtt ccagaccctt
    36061 ggtatacagg agattttgaa gaaacctatc gacgtgttca agagggctgt caagcttggt
    36121 tagaacgttt agaaaaggag agttaaggtg gaaaatctta cgaattttta cgaaaagtat
    36181 cgtgtctatc tgactcgtcc acgtttagag cttttggcag tagttaccat tgttttctgt
    36241 gctgtactcg tcttttttct aaatattcca ggaaaaggtg tcttaaaact cgataatgga
    36301 acgattgttt atgatggcag tcttgtccgt ggtaaaatga atggccaagg taccattacc
    36361 ttccaaaatg gagaccaata tacaggtggc ttcaacaatg gagccttcaa cggaaaaggt
    36421 acctttcaat ctaaagaagg ctggacctac gaaggtgatt ttgtaaatgg tcaggctgaa
    36481 ggaaaaggga aactaacaac agaacaagaa gtcgtttatg aaggaacttt taaacaaggc
    36541 gtttttcaac aaaaataaag cctccttatc aaaggaggta ttattagaat cacaaggtaa
    36601 gcgcttacct gtaaatccct ttctttccaa atccctcttc caagcaagtt tgtgaaataa
    36661 aaaatatttg aaataaattt cacaaacttc aaagataaaa cttgataaga aaagaaaatg
    36721 agaaaagttt cacaagagtt taaaaattct ttgtgaaatg tttatgaaac tgtttacaaa
    36781 gttgaaataa tgcgttataa taaacttgtg aaaaaattaa caaaggatat cgttccttga
    36841 aagctatgga ggaaaatatg gctgataaaa aaactgtgac accagaggaa aagaaactcg
    36901 ttgctgaaaa acacgtagat gagttggttc aaaaagctct agttgccctt gaagaaatgc
    36961 gtaaattgga tcaagaacaa gttgactaca tcgttgccaa agcatcagta gcagctttgg
    37021 atgcccacgg agaattggct ttacatgcct ttgaagaaac aggacgtggt gtatttgaag
    37081 acaaagcaac taagaacttg tttgcctgtg aacacgtagt aaacaacatg cgccacacta
    37141 agacagttgg cgttatcgaa gaagacgatg taacaggatt gactcttatt gctgaaccag
    37201 ttggtgttgt ttgtggtatt actccaacaa caaacccaac atcaacagca atcttcaaat
    37261 cattgatttc attgaagaca cgtaacccaa tcgtctttgc cttccatcca tcagcacaag
    37321 aatcatctgc tcatgcagct cgtatcgtcc gcgatgcagc tatcgcagct ggtgctcctg
    37381 aaaactgtgt gcaatggatt actcaaccat ctatggaagc aacaagtgcc cttatgaacc
    37441 acgaaggtgt tgcgacaatc cttgcaacag gtggtaatgc catggttaag gcggcttatt
    37501 catgtggtaa accagctctt ggggtaggtg ccggaaacgt tccagcttat gttgaaaaat
    37561 cagcaaacat tcgtcaagca gcacacgata tcgtcatgtc taaatcattt gataacggta
    37621 tggtctgtgc atctgaacaa gcagttatca ttgataaaga aatttacgat gaatttgtag
    37681 cagagttcaa atcttaccac acttactttg taaacaaaaa agaaaaagct cttcttgaag
    37741 agttctgctt cggcgtcaaa gcaaacagca aaaactgtgc tggtgcaaaa ttgaacgctg
    37801 acatcgttgg taaaccagca acttggattg cagaacaagc aggatttaca gttccagaag
    37861 gaacaaacat tcttgctgca gaatgtaaag aagttggcga aaatgagcca ttgactcgtg
    37921 aaaaattgtc accagttatt gcagttttga aatctgaaag ccgtgaagat ggtattacta
    37981 aggctcgtca aatggttgaa tttaacggtc ttggacactc agcagctatc cacacagctg
    38041 acgaagaatt gactaaagaa tttggtaaag ctgttaaagc tattcgtgtt atctgtaact
    38101 caccttctac ttttggtggt atcggggacg tttacaatgc cttcttgcca tcattgacac
    38161 ttggatgtgg ttcttacgga cgcaactcag ttggggataa cgttagtgcc attaacctct
    38221 tgaatatcaa aaaagtcgga agacggagaa ataacatgca atggatgaaa cttccttcaa
    38281 aaacatactt tgaacgtgat tcaattcaat accttcaaaa atgtcgtgac gttgaacgtg
    38341 tcatgatcgt tactgaccat gccatggtag agcttggttt ccttgatcgt atcatcgaac
    38401 aactggacct tcgtcgcaat aaggttgttt accaaatctt tgcggatgta gaaccggatc
    38461 cagatatcac aactgtaaac cgtggtactg agattatgcg tgccttcaaa ccagatacca
    38521 tcatcgcact cggtggtggg tctccaatgg atgctgccaa agtaatgtgg ctcttctacg
    38581 agcaaccaga agtggacttc cgtgaccttg tccaaaaatt catggatatc cgtaaacgtg
    38641 ccttcaagtt cccattgctt ggtaagaaga ctaaattcat cgcgattcca actacatctg
    38701 gtacaggatc tgaagtaaca ccatttgccg ttatctctga taaagcaaac aaccgtaaat
    38761 acccaatcgc tgactactca ttgacaccaa ctgtggcaat cgtagatcct gctttggtat
    38821 tgacagttcc aggatttgtt gctgctgata ctggtatgga cgtattgact cacgcgacag
    38881 aagcatacgt atcacaaatg gctagtgact acactgatgg tttagcactt caagccatta
    38941 aattggtctt tgaaaatctc gaaagctcag ttaagaatgc agacttccac tcacgtgaga
    39001 aaatgcataa cgcttcaaca atcgctggta tggcctttgc caatgccttc ctaggtattt
    39061 ctcactcaat ggcccataag attggtgcgc aattccacac aatccacggt cgtacaaatg
    39121 ccatcttgct tccatacgtt atccgttaca acggtacacg tccagctaag acagcaacat
    39181 ggcctaagta caactactac cgtgcagatg aaaaatacca agatatcgca cgcatgcttg
    39241 gacttccagc ttctactcca gaagaagggg ttgaatctta cgcaaaagct gtctacgaac
    39301 tcggtgaacg tattgggatc caaatgaatt ttagagacca aggaattgac gaaaaagaat
    39361 ggaaagaaca ttctcgtgaa ttagccttcc tggcttatga agaccaatgt tcaccagcta
    39421 acccacgtct tccaatggta gaccatatgc aagaaatcat cgaagatgca tactatggct
    39481 acaaagaaag accaggacgc cgtaaataat tgtttatcag tctagaagca agacaaaaac
    39541 tcaatttgag ggaaagaacc agtaattttt ctatgataaa aggcatccta tcaaggtttt
    39601 tgaatacctg ataggatgcc tttttatgat gttgaggcct ttttgccctt tttgaaaaac
    39661 tagaatagaa acaaaatata tagtaggttg aaactagaat agtacacatc tgcttctaaa
    39721 acattgttag aattcgattt gactgtcctg atcgatttgt cctgttctta tttcatttta
//
LOCUS       DAVHSY010000015        38873 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.015, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000015 DAVHSY010000000
VERSION     DAVHSY010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38873
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.015"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(<1..812)
                     /locus_tag="VVR43_000996"
     CDS             complement(<1..812)
                     /locus_tag="VVR43_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6149370.1"
                     /translation="MKKVKLGEVCEILSGYAFKSSQFNDNKIGLPLIRIRDVERGFSD
                     TYFEGTYPEEYLIKNGDLLITMDGSFILKKWEGDLALLNQRVCKIKITDKSVDEGYIS
                     WLIPKFLKEIEDKTPFVTVKHLSVAKIKDISFVLPNKLEQKLIAKKLNTISQIYDFRK
                     IQSEKFNELVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDEL"
     gene            complement(825..2318)
                     /locus_tag="VVR43_000997"
     CDS             complement(825..2318)
                     /locus_tag="VVR43_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU6149371.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            complement(2826..3992)
                     /locus_tag="VVR43_000998"
     CDS             complement(2826..3992)
                     /locus_tag="VVR43_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU6149372.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            complement(4005..4744)
                     /locus_tag="VVR43_000999"
                     /pseudo
     CDS             complement(4005..4744)
                     /locus_tag="VVR43_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            complement(4766..5590)
                     /locus_tag="VVR43_001000"
     CDS             complement(4766..5590)
                     /locus_tag="VVR43_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6149373.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            complement(5727..6941)
                     /gene="thiI"
                     /locus_tag="VVR43_001001"
     CDS             complement(5727..6941)
                     /gene="thiI"
                     /locus_tag="VVR43_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU6149374.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            complement(6950..8092)
                     /locus_tag="VVR43_001002"
     CDS             complement(6950..8092)
                     /locus_tag="VVR43_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU6149375.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLVGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIHQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            8230..8658
                     /locus_tag="VVR43_001003"
     CDS             8230..8658
                     /locus_tag="VVR43_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149376.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENKSNQ"
     gene            complement(8702..10927)
                     /locus_tag="VVR43_001004"
     CDS             complement(8702..10927)
                     /locus_tag="VVR43_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU6149377.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQTELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(11091..13043)
                     /locus_tag="VVR43_001005"
     CDS             complement(11091..13043)
                     /locus_tag="VVR43_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6149378.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            complement(13040..13951)
                     /gene="pfkB"
                     /locus_tag="VVR43_001006"
     CDS             complement(13040..13951)
                     /gene="pfkB"
                     /locus_tag="VVR43_001006"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU6149379.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            complement(13948..14688)
                     /locus_tag="VVR43_001007"
     CDS             complement(13948..14688)
                     /locus_tag="VVR43_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6149380.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPYSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGINGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            14851..14938
                     /locus_tag="VVR43_001008"
     tRNA            14851..14938
                     /locus_tag="VVR43_001008"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14885..14887,aa:Ser,seq:gga)
     gene            complement(15131..15478)
                     /gene="ssrA"
                     /locus_tag="VVR43_001009"
     tmRNA           complement(15131..15478)
                     /gene="ssrA"
                     /locus_tag="VVR43_001009"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(16124..17233)
                     /locus_tag="VVR43_001010"
     CDS             complement(16124..17233)
                     /locus_tag="VVR43_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU6149381.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            17336..18577
                     /locus_tag="VVR43_001011"
     CDS             17336..18577
                     /locus_tag="VVR43_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU6149382.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAISAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            complement(18776..20188)
                     /gene="sufB"
                     /locus_tag="VVR43_001012"
     CDS             complement(18776..20188)
                     /gene="sufB"
                     /locus_tag="VVR43_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU6149383.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     VKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20242..20682)
                     /locus_tag="VVR43_001013"
     CDS             complement(20242..20682)
                     /locus_tag="VVR43_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU6149384.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            complement(20669..21895)
                     /locus_tag="VVR43_001014"
     CDS             complement(20669..21895)
                     /locus_tag="VVR43_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU6149385.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            complement(21906..23168)
                     /gene="sufD"
                     /locus_tag="VVR43_001015"
     CDS             complement(21906..23168)
                     /gene="sufD"
                     /locus_tag="VVR43_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU6149386.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            complement(23196..23966)
                     /gene="sufC"
                     /locus_tag="VVR43_001016"
     CDS             complement(23196..23966)
                     /gene="sufC"
                     /locus_tag="VVR43_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU6149387.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            complement(24116..24310)
                     /locus_tag="VVR43_001017"
     CDS             complement(24116..24310)
                     /locus_tag="VVR43_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU6149388.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            complement(24338..25993)
                     /gene="dnaX"
                     /locus_tag="VVR43_001018"
     CDS             complement(24338..25993)
                     /gene="dnaX"
                     /locus_tag="VVR43_001018"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU6149389.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTTISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTNLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKSEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            complement(25993..26490)
                     /locus_tag="VVR43_001019"
     CDS             complement(25993..26490)
                     /locus_tag="VVR43_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU6149390.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDTMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            complement(26576..27778)
                     /gene="rpsA"
                     /locus_tag="VVR43_001020"
     CDS             complement(26576..27778)
                     /gene="rpsA"
                     /locus_tag="VVR43_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU6149391.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(27940..28011)
                     /locus_tag="VVR43_001021"
     tRNA            complement(27940..28011)
                     /locus_tag="VVR43_001021"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(27977..27979),aa:Gln,seq:ttg)
     gene            complement(28021..28101)
                     /locus_tag="VVR43_001022"
     tRNA            complement(28021..28101)
                     /locus_tag="VVR43_001022"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(28065..28067),aa:Tyr,seq:gta)
     gene            complement(28151..28381)
                     /locus_tag="VVR43_001023"
     CDS             complement(28151..28381)
                     /locus_tag="VVR43_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU6149392.1"
                     /translation="MSKKDKKIEIQVADAKVNVSKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(28549..29193)
                     /gene="pcp"
                     /locus_tag="VVR43_001024"
     CDS             complement(28549..29193)
                     /gene="pcp"
                     /locus_tag="VVR43_001024"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU6149393.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(29208..30131)
                     /locus_tag="VVR43_001025"
     CDS             complement(29208..30131)
                     /locus_tag="VVR43_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU6149394.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(30128..30817)
                     /locus_tag="VVR43_001026"
     CDS             complement(30128..30817)
                     /locus_tag="VVR43_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU6149395.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(30882..31586)
                     /locus_tag="VVR43_001027"
     CDS             complement(30882..31586)
                     /locus_tag="VVR43_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6149396.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(31642..32664)
                     /locus_tag="VVR43_001028"
     CDS             complement(31642..32664)
                     /locus_tag="VVR43_001028"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU6149397.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(32796..35267)
                     /gene="parC"
                     /locus_tag="VVR43_001029"
     CDS             complement(32796..35267)
                     /gene="parC"
                     /locus_tag="VVR43_001029"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU6149398.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(35687..37630)
                     /gene="parE"
                     /locus_tag="VVR43_001030"
     CDS             complement(35687..37630)
                     /gene="parE"
                     /locus_tag="VVR43_001030"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU6149399.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            37766..38407
                     /gene="plsY"
                     /locus_tag="VVR43_001031"
     CDS             37766..38407
                     /gene="plsY"
                     /locus_tag="VVR43_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU6149400.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIMFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVVFGFAPVFCLYLAVVFFGTLYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILNNYDPLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(38452..>38873)
                     /locus_tag="VVR43_001032"
     CDS             complement(38452..>38873)
                     /locus_tag="VVR43_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU6149401.1"
                     /translation="PVLDGFNSEIIAFNLSCSPNLEQVQTMLEQAFKEKHYENTILHS
                     DQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSF
                     KQLEQAIIDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT        11491 a         8604 c         7019 g        11759 t
ORIGIN      
        1 attaattcat cgtagtacgc tacatttcca acagtacctc ttgttgtcaa gactatatca
       61 taacgctcaa gtttgccttt tcgaagtaat ttatcctttg ttttagtgat aaattgcttt
      121 gtatcgaatg aaaatccgtt tttagtaaca ttctttgtat ttaaaaataa acagtactcc
      181 tcactaaaca actcatctga tttaggataa tttttgcccc tatcaccatc tataatatca
      241 aataagttat caatgctttc aaatatttta ttttccccaa acatctcgtt aaatcgggat
      301 ttgacgagct cgttaaattt ttctgattga attttacgaa aatcataaat ttgacttatc
      361 gtatttagtt tttttgcaat tagcttttgt tctagtttat taggcaatac aaatgagata
      421 tcttttattt tagctactga aagatgtttc actgtaacaa aaggggtctt atcttcaatt
      481 tcttttaaaa atttaggaat caaccaagat atataacctt catctacact tttatccgta
      541 attttaattt tacagacacg ttgattaagt agcgctaaat ccccctccca ttttttcaat
      601 ataaaactgc catccattgt aatcaataag tctccatttt taataagata ttcttcggga
      661 taagttcctt caaagtaggt atcagaaaaa cctctttcta catctcgaat tcgtattaag
      721 gggagaccaa ttttgttatc attaaattgt gatgatttaa aagcgtaacc agataaaatc
      781 tcacaaactt cccccaactt cacttttttc atacagccac ctccctactt gagtaatttt
      841 tccaattcag ccaagccagc ttgaatttct ttttctaaat cattgatttt ctttaatatg
      901 acttctgttg gttcatactc aactttttca tactcaatct ctttatattt attgatagac
      961 aaatcataat cattttcctt tatctcagca actggaacaa agaaagattg atccgttctc
     1021 tgacgttctg cttctttttc aagatgatga aagcgttcga taatatctgg aatatcattg
     1081 tcgctaatcg gttgtcgctt atcatccaaa cttaaaccat ccgctttcat atcgtaaaac
     1141 cagactttgt cagtaccacc attaccagtt tttgtaaaga tgagaatggc agttgaaact
     1201 ccagcataag gcttgaacac accactaggc attgagatta cagcatcaag cttatgattc
     1261 tctacaattt cctgacgaat tcctttatga gctttagacg aaccaaaaag gacaccatca
     1321 ggtacgataa ctgctgctcg tccacctggt tttaaagttc gcaagaaaag agaaagaaag
     1381 agtaattctg tttttttggt ttttacggtt gcaagaaggt cattagaggt tgaattgtag
     1441 tcaagtgagc ccttaaaagg aggatttgct aaaaccaaag tatatttatc ggcttcttca
     1501 ttatcttgag acagcgagtc aaggtaactg atttgtggat tttctactcc atgtagcatc
     1561 atgttcatcg ccccaagtct caacatagtc gtatccgtat catttccatg aaacatctga
     1621 ttatgaaaat gattgatatt atctgtattg gtttcccatt catctttctt acgctttaag
     1681 taacggctag cagatactaa gaagccagca gaacccatag cgggatctga gatgatatct
     1741 ttgatagtcg gttgcatcaa ctcaaccatc atatcgatga tgtgacgagg tgtacggaac
     1801 tgtccatttt tacctgcggt cgacaatttt gataacagat attcatagat atctccgata
     1861 tcagtaatac tttgtttgtc attatcaaaa tctacatcta atcccctagt tggaaaaaca
     1921 tctaagatag aaattgcctt ttgaagcgta gcaggtttat ttatttgaaa aatagcttct
     1981 cgcatatatc gtgaaaaggc tgtatcatct gtatccccct tgagattttt aataaacgga
     2041 aaaatctcct gagtcattaa acgataaact tcctgagcat ctcctatatt tttaaaagtt
     2101 gaccaacggt attcaggttt atcttttgga aaaactccct cataaggaat ccctagaaat
     2161 tcagcatcac tttcacgtcc aagctcgaca ctatccaaat ctttcataaa taagagataa
     2221 gtcaactgtt caatatttgt taaaggattt gcgtttcctt ctgtccaaag aatttcccac
     2281 agctgatcga ttttattttt taattcgcct gtaatcatat cttccctttt ctttagtttt
     2341 taaaacttag taatatcatt attttatcag atttcaaaca aagcttcaat taactatatc
     2401 tatgcgtcac ctgaatattt tatactcttc gaaaatctct tcaaaccacg tcagcttcac
     2461 cttgccgtag gtatatgata ctgactctgt cagttctatc cacaacctca aaacagtgtt
     2521 ttgagcaacc tgcggctagc ttcctagttt gctctttgat tttcattgag tattaataga
     2581 cttgtttggt atcctgaaaa ctatatcgta taggtgtcgt catggatcct tttagctgat
     2641 ttaaggatac gaaaacacaa tactatgact aaattgaaat gttaaaattc aatttctagc
     2701 cacctaatcc tgcttcaaat agttatcgaa caagttttat gatagctacc ttgttaggat
     2761 gctcttattt tttaccagac aaaacaaaag gattaaggga gtgaatttcc ttaatccgat
     2821 agttcttatt cttgacgttg tccgaaatca gcaatcatct gatccatttc ttgtcgactc
     2881 ggagttgtca gcatatacag gtaatctcct tgaagttccg cgaaggcagc tggcatgact
     2941 tttttaacct tgaactgctg gctatatttg gcaagcaaat cctcttctga ataaacatag
     3001 tgagcatttg cacggcgaga agtagccaaa caatactgag tttcaaagtc tgacgccggg
     3061 aactcctctc ctgcgacaat agctgcatag ccacgataaa ggtccaagga atgagcaaag
     3121 ttataaacat caatggtaaa accacctgca gggcggttat tgtactcgat ggtaatataa
     3181 tcgtccccct cacggaagaa ctcaatatgg aaaaaccgtt ctttcatacc aaattctttg
     3241 acaattgctt ccccatactt gcgcagttta ggatccatat ccttgagcac ataataagaa
     3301 ttgtccatct tataaatcat gaggtcaagc ggtgtatagg cgtagtcaaa ggttgttgag
     3361 aagacaatct ttccatcctt gtccacgagc ccgtcaaagg tacagatttc gctggaagtg
     3421 acaaattttt caaagaaata aagggttgaa tggtcccatt cttgcttgaa gtgattgata
     3481 tcgtcttctg tctcaagttt aaaggttgcg gctgctccca ctccattatc aggtttggca
     3541 atcattggaa gaccgatttc tttcactgct tgatcaacat ctgcttccgt cttgataaca
     3601 gctccaggta ccacaggaac acctgctttt ttgaaaagtt tcttcatttc agacttatat
     3661 ttcgtctttt tgagatcctc tggtttggca ccaaaaacat tgaattgttc tctgagtgtt
     3721 gcgtctagct caagccagta ttcattgtga gactcgatgc ggtcaattgg accatgttta
     3781 taaaagagaa aagcaactgc acgtttgact tcatctatgt tctcaagatt atcaacacga
     3841 aaatactcgg tcaagctatt gcgcaagggc tcatccaatt gctcgtaaga ctcttgacca
     3901 attcccaaga ctgtgatgcc tttattagct agttcgatgg taaactgttg aaagttttgt
     3961 ggatagtagg gagaaataac aaggtaattc ataggtaact ccttttataa atagagatta
     4021 ccgaggaaat aaggcatttg tttacgccac cattcccagt catgggcgac atcatgtccc
     4081 cattcagcaa accaggctgg aatttgtttc ttgtcaaagg cttctttgag cttgtaaaag
     4141 gatggcaaac catcttgttc ccaggctcca agacccgtac acagcacaat ctctgcctga
     4201 cggtaacggt caataaacca gccgtcgttt tggttccaaa tataatctac tggcgagttt
     4261 tggtaaatag catcatcgtt gtagtaatca ccgacaaaga aacgtgcgtc gtaaacacca
     4321 ctgagagcaa tcactttggt aaagacatct ggatgttgga ggaagaaatt gagtgcatga
     4381 taggctccca tagagcaacc tgtcgtcatc atgccatcaa accaacctga cttgtgcttg
     4441 ataaaagaat ggcctcctca atcacataac attcgtaggc acggtgcatt tccgcttggt
     4501 catgagcatt tttccaagta gccaaccagc tctcactatc caaactagat agggtaaaga
     4561 actggacacg gccttcctcg ataaaggaag cacaggcatc aatcatgcca aaatcatagt
     4621 attcgttgtg actaccacct gatgaagcaa agaccacaac tggaatccca ccatgtccat
     4681 aacggttaag gtacatttca cggttaggat gaccactcca gtggctaaga tgttcaatat
     4741 gcatttcgtt ttttcctttc ttaacttacc atttttctgc aaaaaatctc agacaatctg
     4801 gtagattttc tgaccaaggg atttcactat ggatggcacc agactgaact tttagcacaa
     4861 gattatccag atgtactccc cctgctatca aatcatggta atagcaaagc gacgagtcga
     4921 tataggcttg tttgatattg ccatccatca aggtcttgtc tgtatcatct gcttcttctg
     4981 ttcctacata gatgaagatg cgctggtcag gcgatagttt ctggcactcg atatagcggt
     5041 taaaggcttc ttggtggagc cagtttgcag atgaaaaaac gcccaagcaa ccaatttggt
     5101 cttggtattc caaaccgata aactgggtaa tattgcctcc tagtgaggaa ccaatcatag
     5161 ccgtatgctg gcagtctgct tttgtacgat aggtctcatc gataaaaggc ttgaccacct
     5221 ccatgacaaa ctcagcatac tccacaccct taccaccaaa ctgctgctct gggataggag
     5281 attcttggaa cttccaagcc gcatactcat tcattcgccc cataccatca ttgtcaatag
     5341 caacgacaat catgcgactg atatccggat ttcgtttgat agctgggata atcttccatg
     5401 aatatccaat gaaagactct ttgctataaa aaacattttg cccgtcatga aagtatacaa
     5461 caggatagga acggtctgta tctttctcat aatctttagg aagaagaata cgtacacggc
     5521 gctccttacc tgtataagga accttgagtt tgtgttcttt catttttaga taaaagtagg
     5581 attgattcat tgtcagaaaa ctctctatat tcaaaatttt atatcattat atcatgaaaa
     5641 taaaaaaaaa gttagttttt tacctgtttt tagaaaaaaa actaactttt tttactgatt
     5701 ttcgctattc ttttggattt tctgaattag agtagattat caatcaagtc atcaacttca
     5761 tctttttcgg cttgaggtgt gatttcagta atcatgattc cagccactgc tcgctcaacc
     5821 aagccttcaa catccatacg cgcttcgtac tgctccgcat tcttaatttt aggatttgtt
     5881 tttggacgat ctggtgcaaa aatggtacaa cagtcttcaa acggttggat tgaaatgtca
     5941 aaggtatcga tttcctgggc gatgtcaatg atttccaact tgtccatggt aaccacagga
     6001 cgaatgatgg gagtgttggt aacagcattg atagccttca tactttcaag ggtttggctg
     6061 gctacttgac ctagactttc cccattgatg ataaccaaac catttcgtac ctcacgaata
     6121 cggtcagtaa tccgcatcat aaagcgacga gttagagtca tcaaataagc ttctggcgct
     6181 ttggctttga tttcctcttg aatctctgtg aaaggcacct cgataaactg gatatttccg
     6241 ccaaacttgg tcaatttacg agtcaagtcc tgcgctttct tgagggcacc aggactagta
     6301 tatggtggac tagcaaagtg aactgcctcg atatccaccc cacgcttaag agcaagataa
     6361 cctgctacag gtgagtcaat ccctcctgac aacatgagca tccctttacc tgaagttcca
     6421 actggcaaac caccagcccc acgaatggtt tcataagaaa gataggctgc ttcttcacga
     6481 atctccacct gaagattgat gtcaggactt ttcatttgaa cttgcacatt tggaatggct
     6541 tcgaatacag cccctccaag tgtttggttg agttcacgac tatcaagttc aaagttgtgg
     6601 tcgctacgct tgctagaaat cttaaaggtc ataccttcct tgtagatgtc ccgcataatc
     6661 tcttggacag aagacttcaa aacttctaca gatttttcaa ccttataaac aggagaaaag
     6721 ttttgaattc caaaaacttg tttgagagat tctgcaactg ctgtgtaatc agctccattg
     6781 aggtaagcgt gggcacggtc gcgatctgct gttaccttaa cttgagtata gatagacaaa
     6841 acgtccgaaa tattattacg aagtttattg atgaaacgca tacggttttt acccttggtt
     6901 gacaactctc cgtagcgaat cataatttct gaatactgca tgaatgctcc tatcttactt
     6961 ttctagtttg attgtaaatc aattttaact tggtcaaaaa ctgctcgacc tgactcatat
     7021 cattttccaa gtctaggcta agacgcacag ctgacttggc cttatctttg tccactccca
     7081 tggcaatcaa ggtaccagct ggttttcctg ccttagatga acaagctgag gttgttgaga
     7141 taaaaatatc atagtcttca aaggcgtgaa cgatgacttc acctcgaaca cctttgattc
     7201 caaaagtcag aatatgaggt gcaaagtctt cctcatctga aaagacaaaa atatccggat
     7261 agttcagaag agcttggtga atcactgcct tcatctgccc agtcttgctc ctaaagatat
     7321 ctagcttttc catagataaa cgaagagcct tggctgtcgc tgcaatccct gccacatttt
     7381 cagttgtcga acgataatct cgctcctggc caccacctgt aagaagaggt gtaatcttct
     7441 tgccagattt gatatagaca aagccaacac cacggacacc atgaaattta tgactcgaga
     7501 aggtcgcgca atccacccgt tctgtcagat acttttcagt cggaattttg gcaagcgcct
     7561 gaaccgcatc aacgtggaag gaaatagtcg gcttgtctgc caagaattct gaaatagcct
     7621 caataggttg gatagagccg atttcattgt tcacagccat gatggaaacg aggattgtat
     7681 caggccgtat caaacctgct aacgcctcaa catcgaccaa gcctttctta tcaactggag
     7741 caaaatccac ttcaaatcct tgacttttca accagagggc tgactctttg actgctggat
     7801 gttcaatggc tgaaacaatg atgtgcttgc caaactgagc tttttcaaag gccacaccct
     7861 tgataaccca gttatcccct tctgttccac cagaggtaaa gaagatttca tcgcttttct
     7921 taccgactaa atctgcaatc tgttggcgag aagcatctaa gattcgtgtt gcttggtctc
     7981 ccaaacgatg gagactagat gggtttccta aaatttttga agcgacctgc atataggttt
     8041 caagggcttc aggataaggc ttggtcgtcg ctgaattatc aaagtaaatc atgtttctca
     8101 cgctttctaa aatcactccc tctattgtat catgaaacgg agcttgcgac aagaaagggc
     8161 aatttctctt tttttaagat ttttttaaag aaacagagta taataagtca taatcaaagg
     8221 agagaatgta tgtctaacta tcgtagaact tcaaaaccga aaacagaaca tatcaaaaaa
     8281 ggctttactg tttttcaaaa aaccattact actatcggta gtatccttgg tttgattacc
     8341 gcgggtatca cgatcatgaa cgccttggat aataataaaa atactaaaaa agaacctacg
     8401 acaagccaga cgacaacctt tgtcaaagaa attcaaaaag aatcccctca ggaaaatact
     8461 actccaaata aggaaaataa cacttctcaa gaaaaaacac aacaagaaga aacgccaaaa
     8521 tctagcgtca aggaagagaa aaaagaagat cagaaaacag caactcagga ctctactaca
     8581 cctgctacaa gtaaacctgc cactgaaaat gaaaaacagc ccaatactcc aacttcagaa
     8641 aataaaagta atcaataacc agaaaaatag cttccttcca accttggaaa gaagctattt
     8701 tttattgctg caatactttt cttggcttgg taccttcagc tggaccaatg acacctgcca
     8761 tctcaagctc ttccatgaga cgggtcgcac ggttaaatcc aactgacaaa cgacgctgaa
     8821 tcatggatgc actggctttc tgtgtttcga taaccaaaga cttagcttct tcaaaaagcg
     8881 gatcaccacc agcatctcca tccgaaaatt ctccttcatt ttcagaaacc tcacctggat
     8941 caaaactctc atcgtagtct gcatctgcct gagtcttgat gaagttcaca atacgctcaa
     9001 catcgtcatc cgagataaag gagccttgga gacgaactgg atgattttca tcaatcggtt
     9061 taaagagcat gtctcctcga ccaagaagtt tttctgctcc attttcatcc aaaatcgtac
     9121 gggagtctgt tcctgatgaa accgcaaatg ctacacgaga tggaacattg gccttaatca
     9181 aaccagagat gacatcaaca gatgggcgct gagttgcaag aatcatgtgg atacctgcag
     9241 cacgcgcctt ctgcccaaga cggatgatag catcttccac ttccttgctg gccaccatca
     9301 tgaggtcagc caactcatcc acaatcacga caatgaatgg tagcggaatt tgcttgtact
     9361 cagactggga attgaactct tctaccttgg cattaaaacc tgcaatattc cgaactccca
     9421 ccttggcaaa gagttcataa cggttttcca tttcatccac aaccttttgc agagccttgc
     9481 tggctttacg tggattggtc acaactggaa tcaagaggtg gggaatatca ttgtaaacag
     9541 ataactcaac catcttggga tcgaccatca taaatttaac ttgatctggt ctcgccttca
     9601 tgagaatgct agcaataatg ccgttaactg ctactgactt ccctgaaccc gttgaacctg
     9661 caactagcaa gtggggcatt ttagaaaggt caaaagctct tgcggttcca ttaacagcct
     9721 tccctaaagg aatttccaag aaattttctg ctttcgtttg cgattgttcc catagttctc
     9781 ggaaagatac agtggcaata tcggagttgg gcacttcaat tccgattagg gatttcccag
     9841 gaattggtgc ttcaatccgg acatctttgg cagccaaggc tagagcgagg tcatctgata
     9901 gattggaaat gcggttgacc cttacaccaa cagccggctt gacttcatac ttggtcactg
     9961 atggcccaat ttcggcccgt tcaactgtta ccttaatacc aaagctagca aaggttgctt
    10021 ctaagatttt gatattttct ctgacaattt tcttctcttt agactgatct tttggtttat
    10081 ctggtgcaaa gagttgtaag cttggaagtt tgtattcaag ggcttctttg gctgaaaaat
    10141 cgacctgaac atcttcgtca tctgagtcat cttcctgttc agggaattta agttcagttt
    10201 gaggcaggat gatttctggt tccacccact tttcttctgg aataggtgga agattttgaa
    10261 cagcttcctc tgtcagaatt tcacccgttt ccatatcaac aggaggcaaa tcgagtaagg
    10321 ctttttcagt ctcttcttgt tctaatctag cctctttctc agccttttgg cgagcttttt
    10381 cttcttgttt gacaaagcgt tcctcttttc gacgctcgtg cccttcccac catttggcaa
    10441 agcctctact gaaaaattca gcaatatcgt aaacagacca agggctgact aggagagaac
    10501 ccactaaaat caagatagaa ccaataaagt aagttccgat atttgaaaag agaaaggctg
    10561 ttggaatata aagagcgacc ccgatcaagc cccctccagc aaagctagtc gttcgaaaac
    10621 cagtcagatc tgtcacaacc tgagccatgg tcccttttag aacggacttg tccaaaccat
    10681 atttccaaac caagtaggct tcaaaaatca agagtaagcc agcaaatatg gtgaaaaagc
    10741 cagataagag tccttcctgt tttcgtatcc acttgaaaaa gaagagatag attaataggc
    10801 cgaatatcgc cagataagct aggctaccca ctagcaagcg aattaaatta taaagggtta
    10861 tacctgcagc ccctaatttg aaggctgcga aaatcaataa aatcgcaatt cctaacgaaa
    10921 tcaacattcg ttgaatcgct tcttttcttt ccagttctgc tttagacggt ctccgtcttg
    10981 ttgtacttgt attcttgttt gccattcttc tattatacca tatttcacag gcatttcggg
    11041 aagagaaaaa gactgcacca aacggttcaa tcttttcatt tttctatttt ttatgcttgt
    11101 ggtttgcgta ggtaaccata aaccacacca cttacgattg ctcctaccaa gacagaaacg
    11161 aggtaaagga gagcatttga agtaagggcg ataacgaaga ttcctccgtg tggcgccatg
    11221 agtttgatac cagtaagacc aacgagtcca cctgctactg ctgaaccaag gatgaagctt
    11281 ggaatcgcac gagctgggtc agcggcacca aatggaatcg ctccctcagt gataaatgac
    11341 aagcccatga tgatgtttgt caaaccagag ttacgttctt ccttagtaaa tttatctttg
    11401 aaaagaagag ttgcgacaaa gattgcaagt ggtggcacca ttcctccagc cataactgct
    11461 gccatggcta cagaaccacc tgaagaaaca gttgctgcaa gcgtacctgt accaaagaca
    11521 taagctgctt tattaactgg tccacccata tcaacagcca tcattccacc aaggacgata
    11581 ccaagaagga cagctgaacc tcctccaaga ccgcctagga agtcattcat agcagtgttg
    11641 attgcagcca ttgggatatt tacagctagc ataacaaatc ctgtcaagat tgttccaaga
    11701 agtggcaata gaaggattga tttagcacct tcgagtgaac gaggaacttt aacgtatttc
    11761 ttgatggcaa gaaccaaggc acctgcgata aatccaccaa caagggcacc taggaaacca
    11821 gatgagacac ctgcaagagt tgaagttgct tcaccacctg cggcataagg aattttacca
    11881 aaggcaaaac cttctttggc aatagcacca gccacgaaac ctgctaccaa acctggtttt
    11941 tcagcaatag agtaggcaac ataacccgca aagactggaa gcatcaaacc aaaggcagct
    12001 ccaccaattt tcatgaacat agaagctaac tcatggtaag aaccaagatt gccaaggttt
    12061 tcatttggaa cacccaaagc accgtcaatc aagaaggcaa gggcaatcat gataccacca
    12121 ccgataacga atggtaacat ttgagataca ccactcatca agtgtttgta gaaggcacca
    12181 ccaaggcttt gtttttcgtt agaggctgtt gcagcttttg caccattagc ggcacggtag
    12241 acttcagtat ctcctgaaag agccaagtta attagctctt ctgtcttacg gataccgtca
    12301 gcaactggac gattgatcaa tggttttcca tcaaatcgat ccatttcaac ggccttgtct
    12361 gctgcaatga taatagcttt agccttacgg atatcttctg cagttagttg atttccaaca
    12421 ccgctagcac cgttggtttc gaccttgata ccaaccccca tttcagcagc tactttttga
    12481 agggcttctt gggccatgta agtgtgggca atacctgttg tacaagctgt aacagctacg
    12541 ataaagtcac cagagtcatt agcaggtgct tgaacaagtt cctcagtttt ttctgaagct
    12601 tggtcaaaaa gttcgataac ttggtctgca gatgttgctt gacgaagttt gtctgcaaaa
    12661 ccgtctttca tcaagtattg agacaattct gccaaggctg ccaagtgagt atcattggca
    12721 ccttctggag ctgcaatcat gaagaagagg tcagttgctt gtccatccaa gctctcgtag
    12781 tcaacaccct tatttgactt agcaaataga actgtcgctt ctttgacagc agcgtttttg
    12841 ctgtgaggca ttgcgattcc atcacccaaa ccagtagaag tcaaagcttc acgcgccaaa
    12901 attccttctt taaatgtttc aaaatctgtt acataaccgt ggtctgtcaa atttttaatc
    12961 atctcgtcga tgacagctgt tttttcagtt gcctgcaaat ctagcaacat gacatctttt
    13021 ctcaataggt cttgaatttt catcgttttt ctacctcaac ttttccatat gtttctttaa
    13081 taaattccgc cgttgccaag tcatctgaga aggtagttgc cgttccgcaa gccactcccc
    13141 atttgaaggc ttctactgcg tcttttgatt tgacaaattc acctgtgaat ccagcaacca
    13201 tagaatcacc agctccaact gaatttttga ctgttccttt gattggttta gcgaagtaag
    13261 ctccctcaga tgtgacaaga agggcaccat caccagccat agagataata acattttgag
    13321 cacccttagc cagtaactca cgagcgtatt tctcaatttc atctaaactt tcgagtttaa
    13381 ccccaaaaat cgctccaagt tcatgattgt ttggttttac aagaagaggc tggtagtcca
    13441 aactatcaat taaggtctgt ccttcaaagt cacagaccac ttgcgcacca gtctggcgcg
    13501 tcaaggaaat caaatcctta tagataacat tgcctagatt tttagcactt gaacctgcaa
    13561 agacaactgt atcttctgct gtcagactag ataaaatagc tttcaattct tctagctgaa
    13621 ccgattcaac agttggaccc gttccgttga tttctgtttc ttggtctgct ttgattttaa
    13681 cattgatacg agtatcttct gccacctgga caaaacgtgt ctcgatttct tcctctgcta
    13741 aagtatctgt gataaattta ccagtaaagc caccgataaa tcccgtcgct gtatttggta
    13801 tattcaaacg tttcaagaca cggctgacat tgattccttt cccaccagca aacttatcat
    13861 cactgtccat acgattgaca ctaccaactt tgacttggtc caaacgaacg atatagtcaa
    13921 tggatggatt gagtgtgact gtataaatca tacttctatt acctccgttt tctccttaat
    13981 aacctgcaag agctcatgcc cttgactagt gataacgata gcgcgtttga gtggggctac
    14041 cttggcaaag caagtttgtc caatttttga cgaatccacc aagacgtagg tctgcttggc
    14101 attctccaaa atagctcttt tcacagctcc ctcctccata tcaggagtcg tataatagcc
    14161 atcgtcaaca ccatttattc cgataaaggc acggtcaaag tgcaattggt taatctggtt
    14221 aagagcaacg cccccgatac tagcatctgt cgccgtcttg acgtttcctc caaccatgac
    14281 agttggaatc tgcttttcaa ccaactgagc ggcatggtga atggagttgg tcacaactgt
    14341 aacattctta ttgaccaatt catgaatcaa aaaagcagtt gttgttccag catcgataaa
    14401 gatgacatct ttttctttaa tgagagaggc tgctttctga gccagcaatt tcttttcttg
    14461 aaggtttttg acagattttt cttgaatggt ttcttcttcc tgtaaggagt aggggagttc
    14521 tgctccacca tgcacacgac gaagcttgtt ttccgcttcc aactcatcca agtctcttcg
    14581 aaccgttgat tctgacgttt ctagcaaact aactaatttt tctagagaaa ctacatgatg
    14641 ttgatttaac tcctctaaaa ttagttgttt acgttctgtt tttaacactg aatcacctcc
    14701 tgttatcgtt tacactattc attctatcat actttctttc gaagtcaagc attttttatc
    14761 attttctttc aaaatctatc attttttctt atttctagaa tttttattgc aagataagag
    14821 cctttatggt agactatttg agtaagtatt ggaagattac tcaagaggct taagaggccg
    14881 tgttggaaac gcggtaggcg tgtaatagcg tgcgtgggtt cgaatcccat gtcttccgtc
    14941 gaaaaaagat tatttctagg atgcgacaaa tgttgtatcc ttttttctat ccttttttta
    15001 aaatagggtc tgtttgtgac tcccttttta gcaaaagaat gcaaaggaat accaaagata
    15061 aaaataaaaa acgttgattt aacaacgttt taccaaggaa tgcaaaagaa tgcaaaggaa
    15121 tgcaaaggaa taatggagcc ggtgggagtc gaacccacgt ccaaacacct gccaacatat
    15181 ttgtctacaa ccataggtta tgtattattt taacagcccc tcgacacata actcaagtct
    15241 agaaactgcg agtctatcaa tctcttatca agccgctaga caagacttaa tcgtatctcg
    15301 ctaataataa gacctgtcat tgaacacgag caatccaaat cgggtcacgc ctgctggttt
    15361 ttaagcagct agagcgtaag aagtgttatt ttttgcagtt atatttaact gagcgtttac
    15421 gtcgccacac gagtcgcaaa atatgcctca taatgcctgt cgaatccgta acgaccccaa
    15481 aagacaataa aaccattata ccttatctaa ctcaaaaatg caaaaagaaa tcacatacct
    15541 aaaaaagata ctattcgaga aatttagcaa actggaagac taactacaac tttctcagtg
    15601 cataacttta cgattgtaaa tagagcttac gaaatccaat taacacatac ctaagatgaa
    15661 gctatctgtt ttgaagaaat tcacgaagag aattattcta aaatactttc agatgagaat
    15721 tttcgtactc tctttatttt aattcatttg agtttaaaaa ctataaaatc aatccttata
    15781 ttattcggac tacttttcac ttattgcacc aaaatatagt aaaatgaaat aagaatagga
    15841 cgaatagatc aggacagtca aatcgatttc taacaatgtt ttagaattag aggtgtacta
    15901 ttctagtttc aatatactat aaataggttt cattcgaact ttaatagact atgaaaacca
    15961 gtggaactta ccctgacacg gaattccact ggttttttcg atttttatca gattaacttc
    16021 tactattctt agctgtgaaa attagtttaa gactttaact tattttcagt cttctaatct
    16081 aaaggccact tccagtaaag aaaaatcagg gttctcctga cttttactta gctaattctc
    16141 tttctcgttc tttcattatt ttatgatttt catacaaacg ggataagaac ttagaaattt
    16201 ctttcaagat agaataggtt ggcactgcga caatcattcc aactacacca tagatattgc
    16261 ttgacaacaa aagtaaaact aaaatcgtga ttggatgaac cttcataaca cttcctacga
    16321 ttcgaggata taagatattg ccatctacct gctgaacaac aagcatataa atcactgcaa
    16381 tcagcagtct atggggatca gtgaatatat ttgcgatgat cataggaatc aaaccaatac
    16441 ttggccccac ataaggaatt aaattggcta caccagaaaa aatggcaaaa actaaagcat
    16501 attttaaacc aataatacta tagccaatat aagctaaaca acctataatg attgcgtcaa
    16561 tcgaaactcc actaatatag cgagcaatcg tcgcatttaa attctttaat aagcctgcaa
    16621 tatgcaagcg atccctcttt agaatcgttc tttcaagcat gggcaagaat ttatgtccat
    16681 ctaataagaa ataaaccaaa aaaactggag tcataatcaa aatcaaaaca gtactgataa
    16741 gagctgacaa gacgctcccc acactatttg atacgctatt taggatattt tgaagaatat
    16801 caacatagga taagtttaac tgctgaattg tagcttctac atccaaattc tggagcgcag
    16861 gataattaga taagtctatg attaagtctt gtactcgact ataaatagtt tgactagata
    16921 taatcaaact agataactga ttaatcaaaa taggtaagag atagacaaca cctatgacca
    16981 ttccccagac caaagtacac aaggtaatta aaataccaag caaacgattg agtttacaga
    17041 ctttatttaa gaaagtaaca atagggtttg tcaaataata aagaaagccc cctaataaaa
    17101 atggaatcat aattgtatta agcacgctaa caaaagggtt aatcaaagat cccatctgtc
    17161 tccataggta aaagatgatg gttaagagta aaatttctgt ggtccaaaaa aataatttat
    17221 ttctacgaaa catgagttac ctccctcact ttattttacc atattttcaa aaagcttaac
    17281 agatgaatta ttaaagcaag aatatttttt ttctttatga tagaataaga ctactatgaa
    17341 aaaaatattt ttaactttgt taactgtctc tcttttaggg ggtgcttcta ctgctgttgc
    17401 tcaagatttt accattgccg ctaaacatgc gattgctgtt gaggcaaata ctggtaaaat
    17461 tctctatgag aaggatgcaa cgcaacctgt cgaaattgct tccataacaa aattgattac
    17521 tgtttatctg gtctatgaag ctttggaaaa cggaagtatt accctctcca ctcctgtaga
    17581 tatttctgat tatccttatc aattgacgac aaattctgaa gccagtaata ttcctatgga
    17641 ggcccgtaat tatactgtcg aagagttgct tgaagcaact ctggtatcta gtgccaacag
    17701 cgccgctatt gccctagctg agaaaattgc tggctcagaa aaagatttcg tcgatatgat
    17761 gcgggcaaaa ctcttggaat ggggaattca ggatgccact gttgtcaata cgacaggtct
    17821 taacaatgaa actctagggg ataacattta cccaggttct aaaaaagatg aggaaaataa
    17881 gcttagtgct tatgatgtcg ctattgttgc tcgcaacctc atcaaaaaat acccacaagt
    17941 cttggaaatc accaaaaaac cttcttctac ttttgctgga atgacaatca cttcaaccaa
    18001 ctacatgtta gaaggtatgc ctgcttaccg tggtggtttt gatgggctaa aaacaggaac
    18061 aacagataag gctggagagt cttttgttgg tactactgtc gaaaaaggca tgagagtcat
    18121 cacagttgtt ttaaatgcag atcatcaaga caataatcct tacgctcgat ttacagctac
    18181 atcttcccta atggattata tttcttctac atttacactt cgcaaaatcg ttcaacaagg
    18241 cgatgcctat caagatagca aagcccctgt acaagatgga aaagaagata cagtaactgc
    18301 agtggctcca gaggatatct atctaatcga acgtgttggg aatcaatctt cccaatctgt
    18361 tcaattcaca cctgattcca aagcaatctc agcaccgctt gaagctggaa cagtggttgg
    18421 ccatttgact tatgaagaca aggacttgat tggtcaaggt tacatcacca cagagcgccc
    18481 tagtttcgaa atggtagcag acaagaaaat tgaaaaagcc ttcttcttaa aagtttggtg
    18541 gaatcagttt gtccgttttg ttaacgagaa attataaaaa atcgcgattt taaaccgcga
    18601 ttttttgata caagttcatc ttcaaaatca aagaacaaac taggaagcta gccgcaggtt
    18661 gctcaaaaca ctgttttgag gttgtagatg aaactgacga agtcagtaac catacatacg
    18721 gtaaggcgat gctgacgtgg tttgaagaga ttttcgaaga gtataaaatc aaattttatc
    18781 caactgatcc ctccatttca tagctaatca agcggttcag ctcaactgcg tattccattg
    18841 gaagttcttt tgtaaagggt tctacaaatc ccatgacaat catttcagtt gcctcagatt
    18901 ctgacaatcc acggctcatg agataataca attgctcttc tgaaatctta gatactttgg
    18961 cttcgtgttc caaagccact tgcgagttgt gaatttcatt aaatggaata gtatctgatg
    19021 ctgacaagtc atccatgata atggtatcac attcaatgtg ggaaacagat ttcttagagt
    19081 tcttgttaaa ggtgacttgt ccacggtagt caacctttcc tccaccttta gcgatggatt
    19141 tagacacaat agacgagctg gtatgtggag cattgtgaat catcttagca cccgtgtctt
    19201 ggtgttgccc tgcattagca aaggcgatag agagcatggt accacgcgct ccttctccat
    19261 caaggtaaac agatggatat ttcatagtcg ttttggcacc caagtttcca tcaatccact
    19321 caacagtggc atccttttga gccttagcac gctttgttac caagttatag acgttatcag
    19381 accagttttg gatagttgta taacgcatat aagctccgtc caaagcaaaa atttctacaa
    19441 tggcagcgtg caagctattg cttgaatatg ttggtgctgt acatccttct acgtagtgga
    19501 cgcttgctcc ctcatcaacg ataatcaagg tacgttcgaa ctgacctata ttttcgttat
    19561 tgatacggaa ataagtttga agtggaatat ctaccttgac accttttggc acgtagataa
    19621 aagttccacc cgaccatact gctgagttga gggctgccaa cttgttatct gtcggcggta
    19681 ccaacttcgc aaagtattgt ttaaataagt ctgggtattc cttgagtgcg gaatctgtat
    19741 ctgtaaagat aatacctaat ttttggaact cttccttcat gttgtggtaa accacttctg
    19801 actcgtactg ggcagaagcc cctgctaaat aagcacgttc agcttctgga atcccgatac
    19861 gttcaaaggt ttctttaatc ttttcaggta catcatccca agaacgggct ggtttgtcag
    19921 atggtttttg gtagtagatt aagtcatcaa agtcaatctc tgacaagtct gctccccaag
    19981 tttgcatggg catttttttg aaggtttcat aagacttcaa acggaactcc aacatccact
    20041 caggctcacc cttaacagca gataattcac gaataacacc ttcgttgagt ccttttcctg
    20101 tcgataagac aggctctaca tcgtcatgga aaccaaattt atattcacca aggtcaattg
    20161 gttttggttc tactctttct tcagccatag tatcctttct ttcttcattt ctaataattc
    20221 ataagacaaa agaaacttgt cttactgttt ttcttgattt tcaattgttt tcttaagggc
    20281 attccaagct agggttgcac acttgattct ttgagggaat ttggcaacac ctgacaagaa
    20341 tgccgcgtct ccaagttggc cttgacgctc atctttttgc ccttgaacca tttcagaaaa
    20401 aatagtcgcc agttctaaaa tttcttgttt ggtttttcct aaaacggcat ctgtcatcat
    20461 actagcagaa gcagttgaaa tcgtgcatcc tgaatttaga aaagcaatat cttccaaacg
    20521 gtcctctgca tcaaacttga cagagaggtt gatgacatcc ccacaagtcg gattgttgag
    20581 actgatttgc tcagcatctt ctaacttccc ttggtgatgt ggatttttcg aatggtctgc
    20641 taccactgcc atataaaggc tatctagttt agaaagtgcc attgaaaaac tcctttgtct
    20701 tttgtagggc atcgactagt ttgtcgcaat ctgccttggt attgtagata taaaaacttg
    20761 cacgagctgt tgctgggact tccaaatact gaagcaaggg ttgcgcacaa tggtgaccag
    20821 cacgaacagc cactccttca taatccagag ccgtcgcaag atcgtgagga tggagatcac
    20881 ctaggttaaa ggcaataaca cccgaacgtt gagccaaatc ctgagaaccg taaatggtca
    20941 atccctcaat tgcctgcagt tttggataga cgtacgcaat caattcctgt tcatgagctt
    21001 caacggcatc cataccaatc ttttccagat aatcaactgc agtcgcaagt ccaatagctc
    21061 ctgccatatt tggcgttcca gcctcaaatt tccaaggcaa ttccttccaa ctagcaaatt
    21121 gctcgtagac aaaatcaatc atctcgccgc caaattctac tggagacatt tgctcaagat
    21181 acttttcttt gccgtaaagg acaccgatac cagtcggacc agccatcttg tgacccgaaa
    21241 aggcgaaaaa gtccagatcc aagtcctgga catcaatctt catatgaggt gtagattgag
    21301 caccatccac taccataatt gccccaactt ggtgggctaa ttgagtgatt tccttgatcg
    21361 gattgaccac accaagaaca ttggaggcat gagctaggga aacaaattta accttatcag
    21421 tcaatttagc tcgcaaatcc tccatatcca aggcaccgtc tttaagatag acatagacaa
    21481 gctctgctcc agtctttcga caagcttcct gccatggaat gatattagaa tggtgttcca
    21541 ttactgaaat caagacctgg tctccctcag cgagaatttc ctcagcaaag cgtgccaccc
    21601 agttaaggct ggttgtcgtt cctctggtaa agagaacttc ctttgtagag cctgcattaa
    21661 taaacttacg aatggtttca cgagcagctt cataagaagc tgtcgctcgt tccgctaagg
    21721 tatggacacc acggtgaaca ttggcattgt cctgctcata gtagctgtta atagctttca
    21781 gaactactag tggtttttgt gtcgtcgcag cattgtccag atagaccaga ggttcatcat
    21841 tgacaatctg atctaaaatt ggaaaatcct tgcgaatcgc ttctacatct aacataggct
    21901 tccccttagc gttttgacaa tttctcttcg atagttgcaa tcatttcatc acgaacttcc
    21961 ttgactggaa tctccacgat aacagatcca aggaaaccac gaacaaccaa acgctctgca
    22021 gttgccttat ccaatccacg actcatgagg taatacatgt cttctggatc tacctgacca
    22081 atagaggctg catgtcctgc agttacgtca ttttcatcaa tcaaaagaat tgggttagca
    22141 tctgaacgcg cttggtctga aagcatgaga acacggctct cttgttgcgc atctgctccc
    22201 ttagcaccct tgatgatgtg gccgatacca ttgaaagtca aagttgcttt ttcaaggata
    22261 accccatgtt gtagaatgtt tccgattgag ttgcagccat agttagttac acgagtatca
    22321 atcccttgta cctgacgacc acttgaaaga gctacaacct tgaggtcagc atggctacca
    22381 ttaccaatca agtcactatc aaaatcagca acgacatttc cttcgttcat gacaccgata
    22441 gcccagtcaa tacttgcatc gttgcctaat ttaccacgac ggctaatgta ggcagtgacg
    22501 ttttcaccta gacggtcgat agcagcaaac ttgacttgcg caccagaacg tgcaatcact
    22561 tccactgtga tattggcagt tgctttgtca cttccttcac cgcgtgactc taaacgctcc
    22621 agataactaa tcttagaatt tttaccagcg ataatcataa tatgcttgtt aaacggcaca
    22681 ttgctatcgc tatcttggta gaaaattcct tcaattggct ctgtaatttc tacgttatct
    22741 ggaatataga gtacagcacc actgttaaag taagctgtgt ggtaagccgc caacttgtca
    22801 tcatcatact taacagatga catgaagaat tcttcgatca gctctggaat ttcttctaaa
    22861 gctgagtgaa agtctgtgaa gacaacaccc tgttcagcta actcaactgg agtttgttcg
    22921 aaaacagttt gagttcctac ttgcaccaac ttcaagtgat gatctaaagc tgtgaaatct
    22981 ggaacatttg ctgatggctc attttctgta atcgttccat cacccagatt ccaacggtgg
    23041 aatttgacac gctcaataac tggtaattcc aaagtctcaa tcttgtcaaa agctttttga
    23101 cggagatcag ccaaccagct tggttcagcg tgcatttctg aaaaaagttt aatattttct
    23161 ctagtcattt acttctccta aaagatacga gggaattaca attcttcctt gtagtcgtag
    23221 ccaagttctt cagctaattt tgcgtatcct tcacgttcca aacgcgcagc caattctgga
    23281 ccaccagaaa ggacaacacg accttccatc atcacgtgta ccacatcagg tgtgatatag
    23341 ttcaaaagac gttggtagtg agtgatgatc atagcaccaa aaccttcacc acgcatggca
    23401 ttgacacctt tagacacaac tttaagagcg tcaatatcaa gacctgagtc aatctcgtcc
    23461 aaaagagcaa atgttggctc caacatcaaa agttgaagaa tttcattgcg ttttttctca
    23521 ccaccagaga agccttcgtt gaggtaacgc tctgccattt cttctttcat gttgagcaat
    23581 tccatttttt catctagctt agtaataaac tcacgaactg aaatcttctc atcatcttct
    23641 ttacccgcat tcatagcggc acgaagaaac tcagcattgg taattccagg gatttctgat
    23701 gggtattgca tagcaaggaa aagtcccata cgcgcacgct catccacttc caactcaagg
    23761 atgtttacgc catcaaacaa aacttcacct ttagttactt catagtttgg atttcccatg
    23821 atagcggcag aaagagtcga tttacctgta ccatttggtc ccatgatagc ggcaatttct
    23881 cctgttttca gggtcaggtt aacccctttt aaaatttctt ttccttcaat ctcaacgtga
    23941 agatctttga tctctattac tgacatgata gttcctttct ttttcaaaac ttttacagta
    24001 cttactagaa aaacgtctga tttccccaga aatagagcaa aaattctata aatatacttt
    24061 tctagtataa caaaaaaaag cctaaaaggc tttgattttg tctggaagct gagggctagt
    24121 ctttcctatt aaaatgctga tcgatgacat caacgatttt gcccatcaca taactgactc
    24181 ggaaatttct aaatagtaaa attgcccaaa aggctgccat aatatagcgg ccagtcatcc
    24241 aggcttcatt gaaaaaatag gtctcagcag ctgtaaacag cgccataata ataaattgtt
    24301 gtttattcat aaacttattg tatcatgaaa tctttcttta gtcttcctct accttcactt
    24361 tatcagccaa aaattcaaat ccttctggaa tcaggctttc ttctacttct ttttcagttt
    24421 gagaagattt ggctttggct gaaaaggctg cgcgaacttc tttccattcc tccatggaaa
    24481 tagctaaaat ctcaggtgaa aaacctgccg cctgactgag gatattacca aacatggtat
    24541 tgagattgtc tcgtttcata gtttgaccag cattgaagtt agactcaaaa gcaagaatag
    24601 catggtgttc attggcagca accggttgag aaccaactag cagagccttg tccggcccac
    24661 ctagactttc aattacctct ccccaggcat tctgcaaacg aattaaattt tgacgtgcta
    24721 aatcaggatt ttcgacggcc tcttgtaaga tagattgcac tttattgcga tcgacacgat
    24781 agactgtttt gcccgtagct ggtcgactag gagctggtgc aacttgttta ggaaccgcac
    24841 ctacattaga aagctcttgt ttgagacggg caacttcctg tctcagcgta gcaatttcat
    24901 tttcaaccgc tcctgataga gctggttcgg acttgatttc cgccaaacgg acggtcatca
    24961 tttcagcata aatcttgggc tgcaaactag acttaatatc tgctaaactc actgttgcta
    25021 agcgaatcat ttcaaacaga tttttttgag gaagtgccaa attttctaca aagactgaac
    25081 tatgatgagt attttctccc cctgtttgaa caattaacaa gtctcttaaa tagtgcaaaa
    25141 gattggtcac aaaacgagtc atgctcttac cattgtcaaa aagaagattc aagcaagaca
    25201 aagctttggg aacatcctgt tgagacaagg ccgccacata atcatccaag gctgataggc
    25261 taatggtgcc agtaatttct tcagagatag tagtcgtcag ctcatttccc tgtgtcaaac
    25321 tcagggcttg atccaaaata gacaaggcgt cccgcattcc accttccgcc cgtctggcaa
    25381 tgatttccac agcctctggt tcagaactga tattttcttt ttctaagata tagtgaatat
    25441 gttccttaat atcctgtgtc ttaattgatt taaactcaaa acgttgcaca cgggatagaa
    25501 tagtagcagg aatcttgtgc aattcagtag tggccaaaat aaagactaca ttctgtgttg
    25561 gttcttccag cgtctttagg agggcattaa aagctcctgt agacagcatg tgaacctcat
    25621 ctatgatata aaccttataa cgagcaaggc taggcgcata ggtagattta tcacgaattt
    25681 cgcgaatttc atctacccca ttattagaag ctgcatccat ttcaatgaca tcttctaaac
    25741 taccgtccgt cactgcttga caaatatagc agttattgca aggttcgcca cccacttgat
    25801 tgggacagtt catagccttg gcaaagattt tagcaacact ggtttttccc gttccacgag
    25861 gaccagaaaa aagataagcg tgacttattt tctcttgctc caccgcttgt ttaagagtct
    25921 tagccacaac ttcttgacca actaactggg agaagttttg acttctatat tttcgataaa
    25981 gtgcttgata cattaagatt tttcctcaaa catcgtaaag tcccatgctg tcttttcaag
    26041 caaaatagcg acaaattgtt ccaaataatc tcgatccata gtatcgtaat cctcaatctc
    26101 tgaagaatcc agatccagaa ctccaagtaa ctgaccattc ttcatcatcg gcaccacaat
    26161 ttcactttta gctagactat cacaagaaat atagttgaga taggtcgtca catctccaac
    26221 aataacagtt tcctgaaagt gagctgcctc accacaaaca cccttgccta gtgcaatacg
    26281 gatgcaggaa acacctcctt ggaaggggcc taaaaccaat tcctttccat cgaacaaata
    26341 aaagcctgca aatacggtat taggaaaacg tgattttatg agagcactgg cgttggaaag
    26401 attagccaaa acattggttt cgccttccaa taggaaggac aattcttcat ttaacatttg
    26461 ataacgtgat tgtttttctg attttaacat agaactatta tatcaaaaaa ggagcagaga
    26521 caaaagaaaa atcccttgtt tagtaaacaa aggattttgt gaattttcaa tttgattaaa
    26581 gttcgatatc accaaacaaa tcagccattg aaaatcctgt ttgtgtttct ggaagttcga
    26641 aatcacgctt ttcttgacgt cttggacgac gtggacgagc agcacgtttt tcttcttttt
    26701 gtccttcttc ttgggctgga cgttcttcaa gagctttaat agaaagtgac acgcgttctg
    26761 catctgcgtt aacttcaaga actttaactt gaacttcttg accaacttta agagcttctt
    26821 ttggattttc aatccgtttg tgtgaaattt gtgatacgtg aacaagtcca tcgatacctg
    26881 gcaatacttc aacaaatgca ccgaagtcag tcaaacgttt aactgttcct tctactacat
    26941 cacctttagc caatttttgc tcaacgccat cccatggtcc tggtactgtt gctttaagtg
    27001 aaagtgatac acgtccttct tcttcgttaa gatcaaggat tttcacttca atttcttcac
    27061 caacagttac aactgatttt ggtgatacgt tacgttcatg tgacaattca gtcaagtgaa
    27121 ccaatccgtc aacaccacca aggtcgatga aagcgccgaa gcttgtgata cgagcaactt
    27181 taccagttac aacatcacca acagccaatt taccgaatac ttcagcgcga gctgctgcag
    27241 tagctgcttc aacaacttca cgacgtgaaa ggatgaaacg gttttcttta gcgttaactt
    27301 ctttgatttt agtatcaaat tcttgaccta caaaacgctc agcgttacgt acgaaacgag
    27361 tatccaacat tgaagctggg ataaatccac gaacaccttc aaattctact gaaagtccac
    27421 ctttaacggc acgcgttcct ttaacagtaa caacttcttc ttcgcgacca acaagtttgt
    27481 cccatgcttt gcgagcttca aggcgttttt tagatacaag gtatgtaact gtatcagtat
    27541 ctttaccaac tacttgacga agtacaagaa catccaatac ttctcctact ttaacaaagt
    27601 cattgatatc tgcatcacga tcgtttgtca attcgcgaag agtcaagaca ccttcaacac
    27661 cagttccaga gattgcaacg ttagcttgag tcgcatcaac tgtcaatact tcagcactaa
    27721 caacatcacc agtctcaact tgactaacgc tatttagcaa atcttcaaat tcgttcatct
    27781 aaaaaatcct ccaacaatca agtttttctt aaacttgaca tacttataat ttttttccta
    27841 agcacccgca aggacatgtt catatcattc acgtctttca attataaaaa taaaataccc
    27901 taagatattt tgctttttat cttgattatt acctaagaac tggggtagct ggattcgaac
    27961 caacgcatga gggagtcaaa gtcccttgcc ttaccgcttg gctatacccc attaatgaaa
    28021 tggagagaga gggattcgaa cccccgaacc cgaaggagcg gatttacagt ccgccgcgtt
    28081 tagcctcttc gctatctctc ctacaatcaa catggactat tatatcatga aaatttcaaa
    28141 aaaacaagac ttattttgct aaattataat tttcaatcaa aatttccaca gctttttcca
    28201 attttttata aaaactatcg acattcccat tctttataat ggcaaattgt ccgtctaatt
    28261 cggcaatttc tccgataact tttttaccga tagtcaatgt ataaccttca aaactgtctt
    28321 tactaacatt aactttggca tccgctactt gaatttcgat ttttttatct ttcttgctca
    28381 tttcatacct ctcttcactt tttctatttt acaagaaaat cctaaaacta gcaagaaaaa
    28441 actctatatc aggcttctct gatatagagt tttatgtaaa caacctcaat tgatttagca
    28501 tagttaatag ttagtaaaca agcataattg actatccttt ttaggttatc agtgagtctc
    28561 accgcctact aactgcaaat ccttatcttt gtagtctaca atagcttcaa tagctacctc
    28621 tatgcctctt acaatatcac atagactcat tcctgcagta ttcggcttat ttactacttg
    28681 ttccatcata tatggaatat gcatgaaacc tgctctcata ttagggaatt ttttatccac
    28741 taaataaaga gcttggtaca tcaaatgatt gcaaacaaag gttcctgcac tattggatac
    28801 aactgccgga agtccctgtt ttttgatagc ttgtaccatc gctttgatag gtaaactact
    28861 aaaataggcc gatgctccat caatacgaat cggtgtatca attggttgat tgccttcgtt
    28921 atcaggtatg cgagcatcat cttgattaat agccactcgt tcaggtgtta agccggtcct
    28981 gccgcctgct tgtccaatac aaagtacagc atctggttga tatcgtaata tttctgcctc
    29041 taaaacttct gacgacttat aaaaaaccgt tggaatttct acccagcgaa cttcagcccc
    29101 attaatctca gatggtaata attttacagc ctccaaagct ggattaatct tttcacctcc
    29161 aaaaggatta aaacctgtaa ccaatatttt cattttattt tcctttacta aaatgcgaga
    29221 aagtacatta agaatatgtg aataacaatc attactagag caacacctgc ttgagccttt
    29281 ataacgccat tctgatcttt catatccatc aatgctgctg gtagagcgtt aaaattagca
    29341 gccattgggg tcaataaggt cccacaataa cctgctgtca tggcaagagc accagccaca
    29401 attggattag ctcccagagc aaatacaaag ggaactccaa cacctgctgt aataacggtg
    29461 aatgctgcaa aagcatttcc cataatcatt gtgaatagaa ccattccaag aacataggcc
    29521 aaaactccta taaagcgact atctgaagga acaataccgc taatcagatg agagataaca
    29581 tcaccaacac ctgctacagt aaaaatagcc cccaaagccc ctaataattg aggaacaatc
    29641 ccacttgttg aaacttgctg agtcattcga ttattttctg ataacagact cttagggtga
    29701 ctattggtaa tcacaagaac agaaattgta gcaaacaagg cggcaaggct aatcgaaatc
    29761 ttgctaaatt ctggaatcat ttgcgctaag accaacgcaa gtattgccat cagcataact
    29821 ggaataaaaa ttttattttt caacctgtta gattcaatat tggctttcat ttcatctaag
    29881 gatggcaagg ttccgatacg gacttgctta aacaatgtta acagcgataa taggattaca
    29941 ataataccaa tactcatatt tggcatatag gaaccaccta taaacgtaat agacaataga
    30001 gtccaaaatg cagatgtccc aagtcgaact gggtttgttt tatctttata actacaatag
    30061 gctgtatgga gaaattgaca accaatcaca atataggtca actctaatag ttgctttgcc
    30121 aactctgtca tttttgttct cctcccctag tcttttttga tatcaatttt ttatcaaata
    30181 aataattgta aatccccact acaataagtg ttataacagc aacaataata gatgtagaag
    30241 caatccctgc ataattgctt tcatagccta actgatctaa tgttccccct atcaagagga
    30301 ctcccccagc acctacaaac gtattttgag caaagaaatt tccaaaattt tcattcgcag
    30361 ccgcacgcgc ttttattgtc tcatcttcaa cctctgttaa ctttctacct aattgagact
    30421 ctgcagctgc ttctcccata ggttgaacca aaggtctgac aaactgaggg tgtcctccta
    30481 gacgaattga aaagaaacca gctaactctc gaataaagaa ataaactgta tagaagtttc
    30541 caactgtcag acctttaatc tttcgaatca aatcgattga tcgttgcttg agtccaaagg
    30601 tttctgacag ccccacaaga ggcaaggtaa ccataaaaat cgtgagcact cgctgattgc
    30661 taaattcttt tcccaaaatc tccaaaaatt caacgagaga aacacctgaa actaaagctg
    30721 taaccaaacc agctaagact actgttgcaa ttgtatcaaa ttttaaaata aaacccacaa
    30781 caatgattgc tattcctatt aatctaatcc actccatatc aaactccttt atattcaaaa
    30841 tgacagtatt ttaaaaattt tatcaagatc aataccattc cttatttaat gtatttttct
    30901 agttcttttt ggtatttgct attggattcc aatttttctt tttgccattt tttaaaaacc
    30961 tcgttatatt cttttgttgt aacaatatct ttttgcaatt tcattccttt aaagatatat
    31021 ggttccccct taataccaac ttgtgagtat ggttttgaga atggtactac gttacttaca
    31081 actggaaaac caccagatga agctgttggc atcaataatg aactatctgt cgaccaagct
    31141 tgagctttgg catatttttc atatctcttc tctaggtcag tggtctcaga aacagcatct
    31201 tctaacaatt tcttatattt atccaaacca ggtttagcta caacatcctt atcttttcct
    31261 ttcgtaatgc caaggtgttt catggcagaa ccagattttg gatccataat attcaagtaa
    31321 gacgctggat cttgatagct tggagcccat cctgtactgt tcaaatcata gtctttttga
    31381 gaaggagcaa cattgccgta tttatcattt tccatcaaac catcaataac atttccaata
    31441 acgtctgtcc tcgatgttcg agtcgctata ctgtagccca atgatgctgg atctactgca
    31501 tagacataag aaaatgttgt cggtgcatct gcttctttat cagtttttcc acaagccact
    31561 aaaatagctg acgtgctcag gaccactcct gctgttaaga gccacttttt ctatttcata
    31621 aaaaatctcc tttggtttat tttaatctac ttttacaatc caaccttctg gcgcttcaat
    31681 atcgccaaac tgaatacccg tcaattcatt atataattta cgcgtcacag gacctacttc
    31741 tgtttcacta tagaatacat ggaaatcatc accatgttga atacctccaa ttggagaaat
    31801 aaccgctgct gtaccacagg cacctgcctc tacaaaacgg tcaagattat caattggaac
    31861 atcaccctca ataggagtta atcccaagcg atgttctgcc aaataaagca aggaatactt
    31921 ggtaatagat ggcaagatag atggactcaa tggtgttaca aattcattat cagctgtaat
    31981 tccaaagaag ttagctgatc cgacttcttc aatctttgta tgagttgatg ggtccagata
    32041 gataacatct gagaaatggc gtgacttggc catttttcct ggtaagagac ttgcagcata
    32101 gtttccacca accttagccg cacctgtacc atttggtgct gcacggtcgt actcatcctg
    32161 aatcaagaaa ttggttggga ccaaaccacc tttaaagtaa tttccaactg gcatagcaaa
    32221 gatggtgaaa atgtactctt ctgccggttt taccccgata atatctccga caccaatcaa
    32281 aagagggcga agatataagg ttccacctat tccgtatggt ggtacgtatt cttcattcgc
    32341 acggacaact gctttacaag cttctacaaa catgtctgtc ggaacttgtg gcatcaagag
    32401 acggtcacat gtacgttgca ggcgtttagc attttcatca ggacggaaca gttgaacact
    32461 gccatcctta gtacgataag ctttcaaacc ttcaaatgct tgttgtccat agtgaagact
    32521 tggagaagac tctgaaatat gcaaagttgc atcctctgta agctctcctt gatcccattg
    32581 tccatttttg aaatgagcaa gatagcgata aggtaatttc atataggaaa aaccgaggtt
    32641 ttcccaatca atcgttactg tcatattcca ctccttattc taaaaaccta tttcttatat
    32701 tctacactat ttttctaaaa tagcaagtat attttgtaat tttcagaaaa tttctccaat
    32761 aaaaaccagc tcttagaact gattcttcat ttcacttatt tatcttcagt aactacttcc
    32821 tgaagataag cgtcaaaaac ttcttcatct gaaatcgtgt cagaaatgaa gcttccattg
    32881 ctagtgcgtt ctgacaagtt caagtcttgc aatcggcttt catagattgt tcctttattg
    32941 gattggacaa gcagagtttg gtcgttcaca tccacttccg tactgaagaa atcgccaaca
    33001 aatccttgct ctgcaactgc tcctgccaag aagacacgat gcggtttgtt tttcaactca
    33061 cgcaagactt gtaatcctcg tttggcacgg ctggttgcta gaatttcctc aatggaaaca
    33121 cgtttcaagc ttccacgctg ggtcaagagg tagaaggacg aagtattaca gataaagcca
    33181 gattggagga catcatcttc tttcaaattc atagccttga cacctgctgc cttagcaccg
    33241 acaaccggaa cctcttcgat attgaaacgc agggcataac cattttgact aaccaagaca
    33301 acatcatcta gtttaatcgg agccactgct acaatctgat ctgtatcgtc tttgagctta
    33361 gcatacttga cagacttaga tctataggtc cgccatggag tgaattcttt tcgctctacc
    33421 cgtttgattt gaccaaggcg agtcactgca aagtaggttg tcgcatcgtc aaactgatcc
    33481 agtacttcca cataaaggat ttcttcattc gtttcaaagt ttgtgatggt ttggctcaga
    33541 tgctctccga tgtccttcca acgaatatct gccaactcat ggattggtct gtagatgaca
    33601 tttccaagac ttgtgaacat caagaggtgc tgggttgtct tggcagattg aacaaaaatc
    33661 aaacggtcat catcacgctt gccaatttct tccaaggtgg aagccgcaaa ggaacgtgga
    33721 ctggtacgct tgatgtaacc tgccttggtc acgctgacgt aggtatcttc ctcagcgata
    33781 agactagctg tatcaatctc aattgctttc gcagtgtctt ctaaagaact caaacgagga
    33841 gttgcaaatt tcttcttgac ctcacgaagt tctttcttca tgagattgta catagtcctt
    33901 tcatcaccga taatagccgc cagcatagca atcttctcac gaagctctgc ttcttcttcc
    33961 tgcaagacaa ccacatcggt attggtcaaa cggtacagtt gcaaagttac gatagcctca
    34021 gcctgttctt ccgtaaaatc atagctaact ttgaggtttt ccttggcgtc cgccttattc
    34081 tcagaagcac ggataagagc aatgacttca tccaaaatcg aaatcacacg aatcaaacct
    34141 tcgacgatat ggagacgttt ctcagccttt tctttgtcaa agcgtgaacg cgccaaaatc
    34201 acttctcgac ggtgagcgat gtagctagac aggattggaa caatcccaac ctgacgaggt
    34261 gtgaaattgt caatcgccac catattaaag ttgtagttga tttgtaggtc ggtgtactta
    34321 aataagtagt tgagaacaag ctcagtatta gcgtctttct taagttcgat agcgatacga
    34381 agaccatcac ggtcagactc atcacgaacc tcagcaatcc cagctacctt gttattaaca
    34441 cgaacatcat cgattttctt gactagattg gccttattga tttcataagg aatctcagta
    34501 ataacgattt gttccttacc accttttagc ttttcaattt cagtcttgga acgaacaacc
    34561 acgcgccctt tcccagtctc ataagctttc ttgatttcat cacgaccctg aataatagcc
    34621 cctgtaggga agtctggtcc aggcaagaat tccatgagtt tatcaatctt tgcagttggg
    34681 tggtcaatca tgtaaactgc agcatctatg acctcagcta aattatgggg aggaatgtct
    34741 gtggcataac cagccgaaat cccagtcgaa ccattgacca agaggtttgg aaaggctgct
    34801 ggcaagaccg ttggttcttt ctccgtatcg tcaaagttcc atgcaaaagg aactgtcttt
    34861 ttctcgatat cctgaagaag gtagcctgca atttcagaca aacgtgcctc agtataacgc
    34921 atagccgcag gaggatctcc gtccatagaa ccgttattac cgtgcatttc aactagaatc
    34981 tcacgatttt tccagttctg tgacatacga accatggcat catagataga agaatccccg
    35041 tgtgggtgga aattccccat gatgttcccg actgacttgg ccgacttacg gtagctcttg
    35101 tcaaaagtat tgctatcctt attcatagaa taaagaatac ggcgctgaac cggcttcaac
    35161 ccatcacgaa tatctggcaa agcccggtct tgaataatgt acttggagta gcgaccaaag
    35221 cgctctccca tgatgtcctc cagggacatg ttttgaatgt tagacataag atacaaagcc
    35281 cataaaatac caagtgaaaa tagaaaattc ttgaagtaag caaactcaca agagaattta
    35341 tctttttcac acagtatcta gggcgtgttc aactcctttc aaagaatgta gagtaggttt
    35401 ttatgcagta aaagatattt tacgggaatt cgtcccgtgt tcagttacga taagtaacca
    35461 aactatcctg tttgtatttt tcaatatgaa aatatggttt tccaaaatta gtcttagttt
    35521 gtgtcttagc cgctccctta aacgcctctt tgagataagc actcatagca gattcttcat
    35581 taataatcct gcaatttttt caaaccaaga ttttcaaact gctttttcac atagtcattc
    35641 acatccgact ctaatttcca gtttactaac atattatttt ctttcattaa aacactgtcg
    35701 cttcttctag cgtaaacttg acattatctt caatccattt acggcgtggt tctaccttat
    35761 ctcccatgag aacattgacg cggcgttcgg cgcgcgctaa atcttcaatt gtgacacgga
    35821 tgagggtacg tgtttctggg ttcatggttg tttcccagag ctggtccgca ttcatctcac
    35881 caagtccttt gtatcgttgg agggtagcgc ctttaccgaa ctgtttacgg agttcttcta
    35941 gttctccgtc cgtccaagcg taggccactt cttctttctt gcctttacct ttggacatct
    36001 tgtaaagagg tgggagggca atatagacat gacctgcctc gactagcgga cgcatgtaac
    36061 ggtagaaaaa tgtcaagagc aaggtctgga tatgggcacc gtcggtatcc gcatcggtca
    36121 tgataatgat cttatcatag ttggcatctt caatagagaa gtctgctcca acacccgcac
    36181 caatggtata aatcatggta ttgatctctt catttttgag gatatccgcc atcttggcct
    36241 tggctgtatt gacaacctta ccacgaagag gtagaatagc ctggaacttg cggtcacgac
    36301 cttgtttggc agaaccaccg gcagagtccc cctcaactag atagagttca ttcttagcag
    36361 gattcttaga ttgggctggg gtcaatttcc cagacaacaa gcccttatct ttcttgtttt
    36421 tcttcccatt tcggctctca tcacgcgcct tacgtgctgc ttcacgagca tcacgggcct
    36481 tgatagcctt gcggatgagg ttagaagcta attccccatt ttccataagg aaaaaggtca
    36541 acttatcagc cactattcca tccacaactg ggcgagctag ggggcttcct agtttatcct
    36601 tggtctgtcc ttcaaactgc aagtgttctt caggaactaa gatagaaaga acggccgcta
    36661 gtccctcacg atagtctgaa ccttcaaggt ttttatcttt ttccttgaga agacctgttt
    36721 tacgtgcata gtcattcatg accttggtaa tggcagactt gagtcctgtc tcgtgcgttc
    36781 caccgtcctt ggtgcgaacg ttattgacaa aggatagaat gttatctgag aatccgtcat
    36841 tgtactggag ggctacttcc acttgaaaac cattgtcttc cccttcaaag taaagaactg
    36901 gcgtcaagat ttccttatct tcgttgagat aagaaacaaa atcttgtact ccattctcat
    36961 agtggaactc aatcgcttca tctgttcgct tgtccgttaa agacaaggtc acatttttca
    37021 agagaaaggc tgattcatta aggcgctctg aaatggtatt gtacttgaaa tctgtcgtag
    37081 aaaagatagt cgcgtcaggc ataaaagtaa ctttggtgcc tgttttagac ttgggtgctg
    37141 taccgatttt cttcaaagtc gtgacaggtt ttccaccatt ttcaaaacgt tgcttgtaaa
    37201 ctgcgccatc acgggtaatt tcaacttcta accagctaga aagggcgtta acaacggaag
    37261 aacccactcc gtgaagtcca cctgatgtct tatagccacc ttgaccgaat ttccctccgg
    37321 catgaagaat ggtaaagata acctcaacag ttggaattcc catagcgtgc atacctgtcg
    37381 gcatcccacg tccatggtct tgaaccgtta gactaccgtc tttattgatg gttacatcga
    37441 tacgatcacc aaacccagac aaggcttcat cgactgcatt atcaacgatt tcccaaacta
    37501 ggtgatgaag accagcgcca tcggtcgatc caatatacat ccctggacgt tttcggaccg
    37561 catccaaccc ttctagcacc tgaatagcat catcattata attgttaata ttgatttcct
    37621 tttttgacac aaggaacctc ctattcgttc atctttacta ttctacaggt tttccaagga
    37681 ttttgcaaaa tttttctttc tccgatgtga caattttagc agagattctc tgcttttctt
    37741 tcccaattca tgatataata ggagtatgat tacaatagtt ttattaatcc tagcctatct
    37801 gctgggttcg attccgtctg gtctctggat tggacaagta ttctttcaaa tcaatctgcg
    37861 tgaacatggt tctggaaata ccggaacgac caataccttc cgcattttag gcaagaaagc
    37921 tggtatggca acctttgtca ttgacttttt caaaggaacc ctagcaacgc ttcttccgat
    37981 tatgtttcat ctacaaggcg tttcgcctct catctttgga cttttagctg taatcggcca
    38041 taccttccct atctttgcag gatttaaggg tggtaaggct gtcgcaacca gtgctggagt
    38101 ggttttcgga tttgcgcctg tcttctgtct ctaccttgca gttgttttct ttggaaccct
    38161 ctatctaggc agtatgattt cactttccag tgtcacagca tctatcgcgg ctgtcatcgg
    38221 agttctactc tttccacttt ttggttttat cctgaacaac tatgaccctc tcttcatcgc
    38281 tattatctta gcacttgcta gtttgattat cattcgtcat aaggacaata tagctcgtat
    38341 caaaaataaa actgaaaatt tggtcccttg gggattgaac ctaacccatc aagatcctaa
    38401 aaaataaaat gccagttctg tgaactgcac cccaaaagtt agacaattaa tttatccgaa
    38461 ggatttagtt ctgtattgca cagggctaag tccttttagt tttaccttaa ttcgtttatt
    38521 gttgtagtaa tcaatatagt ctataatagc ttgttccaat tgcttaaacg actgaaacga
    38581 cttctcataa ccgtaaaaca tttccgattt cagaatccca aagaaggact ccatcatacc
    38641 attgtctggg ctgttaccct tacgtgacat ggatgcttga attcccttac tctctaggaa
    38701 ccgatgataa gaatcgtgtt gatattgcca gccttggtca ctatggagaa tcgtattctc
    38761 gtagtgcttc tctttgaatg cctgttccaa cattgtttgt acttgttcta aattaggcga
    38821 acaagaaaga ttaaaagcaa taatttcact gttaaagcca tctaaaactg gtg
//
LOCUS       DAVHSY010000016        38447 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.016, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000016 DAVHSY010000000
VERSION     DAVHSY010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38447
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.016"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            131..868
                     /locus_tag="VVR43_001033"
     CDS             131..868
                     /locus_tag="VVR43_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6149402.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPYLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            865..2556
                     /locus_tag="VVR43_001034"
     CDS             865..2556
                     /locus_tag="VVR43_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6149403.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            2672..3235
                     /locus_tag="VVR43_001035"
     CDS             2672..3235
                     /locus_tag="VVR43_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU6149404.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            3257..8965
                     /locus_tag="VVR43_001036"
     CDS             3257..8965
                     /locus_tag="VVR43_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6149405.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVEAEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKGPEQPVQPTQAEQPRIPKDSSQPEDPKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETKTAKGTQEEGKEGQAPVQEVNPEYKVTTGTVEKSTESELDFTTEV
                     VPDDTKYVDEEVVERQGSKGVQVTKTTYETVEVVETDKVLSTTTEVKTPAVPKVVKKG
                     TKPVKGTAVETREEVIPFATKEQEDDTLKRGTRQVAQEGVNGKKQITETYKTIRGEKT
                     NEAPTVEETVLQAPQDEIIKKGTKGLEKPTLEWVKTDKDVLKKSATASYTLNKPDGVE
                     IKSIKVALKDNTGTVIKEVTVEENNLNATLDNLKYYQGYTLSTTMVYNRGEGEETETL
                     EDKEVQLDLKKVEIKNIKETSLMSVDDAGVETDKSLLTEKPTDVAPLYLRVTTHDNKT
                     TRLAVSSVEEVVVDGKTLYKVVAKAPDLVQRREDDTLSEEYVHYFEKQLPKVDNVYYS
                     FNELITDMQKNPTGTFKLGADLNAANTPTPSKSYVTGEFKGKLSSVDGQHYTIHNTAR
                     PLFNNIVGGTVKNINLNNVNIDMPWADQIASVANVIKGGSLIENVKVKGNVLGRNWVS
                     GFIDKIDSGGRLVNVAFIGNVTSVGDGDKFLTGIVGENWKGYVEKAYVEANIKGKRAK
                     AAGISYWSQNSGDNNAVGRDGAIKKSVVKGSIDVEKPIEVGGAVGSLNYLGYIEDTVA
                     MMKVKNGEIFYGSHDIDTDPYYTGERVNRNFIVDGVSEGKSSYTYSKQQKRIKSISQE
                     EADKKIKELGITADKFTIIDPIVNKLNNIKQKADTYKDTQDYKADRELTYRNIEKLQP
                     FYNKEWIVDQGNKVPSNSKLLTTEVLSVTGIKSGQFVTDLSDIDKIMIHYSDGAKEEL
                     NVTRQESNVQQVREYSITDLDILYTPNMVEKDRAQLMTDVKSKLSSVELESDGVRQLL
                     VKRDTKKDANANSVGRQNGYIRDLFLEESFSEVKANLDKLVKQILENEDHQLNDNELA
                     ERALLKKVEDNKAKIMMGLAYLNQYYAFKYDELSIKDIMMFKPDFYGKTASVIDRLIN
                     IGSAENNLKGDRTQDAYRGIISGATGKGSLHDFLTYNMKLFTNETDINVWFKKAIEKN
                     AYVVEQPSTNPAFANKKYRLYEGINNGQHGRMILPLLNLKNAHLFMISTYNTISFSSF
                     EKYGKDTDEKREKFKSEINKRAKEQVNYLDFWSRLATDNVRDKLLKSQNVVPTPVWDN
                     HNSPNGWASRHGHIDGKPDYAPIREFFGRINKYHGYKYGYGAYAYIFAAPQPMDAVYF
                     VMTDLISDFGTSAFTHETTHVNDRMAYYGGHWHREGTDLEAFAQGMLQTPSVSNPNGE
                     YGALGLNMAYERQNDGNQWYNTNPNDLTTRAEIDNYMKGFNDTLMLLDYLEGEAVLNK
                     ANQDLNNAWFKKVDKQLRGASTKNQYDKVRDLTADEKNITLNSVDDLVDNNFMTKHGP
                     GNNVYDPTGFGTAYVTVPITAGIYGGNTSEGAPGSMSFKHNTFRMWGYYGYEKGFLNY
                     ASNMLKNESRQAGHNTLGDDFIIKKVSDNKFSTLEDWKKAYFKEVVDKAKAGFNPVTI
                     DGTTYSSYDDLKNAFAAAVEKDKATLKNGSVKSDNTVALKEKIYKKLLQQTDSFKTSI
                     FR"
     gene            9026..10747
                     /gene="pabB"
                     /locus_tag="VVR43_001037"
     CDS             9026..10747
                     /gene="pabB"
                     /locus_tag="VVR43_001037"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU6149406.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLTVHKVPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKDQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGKISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            10748..11365
                     /locus_tag="VVR43_001038"
     CDS             10748..11365
                     /locus_tag="VVR43_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6149407.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            11415..12413
                     /locus_tag="VVR43_001039"
     CDS             11415..12413
                     /locus_tag="VVR43_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU6149408.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQAATTQTDTTSSTASGWVKQDGS
                     WYYFDGNGNLVKNAWQGNYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYARNAWQGN
                     YYLKSDGKMAKGEWVYDATYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKTYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            12540..13499
                     /locus_tag="VVR43_001040"
     CDS             12540..13499
                     /locus_tag="VVR43_001040"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU6149409.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            13596..14435
                     /locus_tag="VVR43_001041"
     CDS             13596..14435
                     /locus_tag="VVR43_001041"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU6149410.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(14482..14652)
                     /locus_tag="VVR43_001042"
     CDS             complement(14482..14652)
                     /locus_tag="VVR43_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU6149411.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            14773..15657
                     /gene="miaA"
                     /locus_tag="VVR43_001043"
     CDS             14773..15657
                     /gene="miaA"
                     /locus_tag="VVR43_001043"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU6149412.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVLHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            15650..16888
                     /gene="hflX"
                     /locus_tag="VVR43_001044"
     CDS             15650..16888
                     /gene="hflX"
                     /locus_tag="VVR43_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU6149413.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            16881..17504
                     /locus_tag="VVR43_001045"
     CDS             16881..17504
                     /locus_tag="VVR43_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU6149414.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            17519..18448
                     /locus_tag="VVR43_001046"
     CDS             17519..18448
                     /locus_tag="VVR43_001046"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU6149415.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            18469..19224
                     /locus_tag="VVR43_001047"
     CDS             18469..19224
                     /locus_tag="VVR43_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU6149416.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(19278..20186)
                     /locus_tag="VVR43_001048"
     CDS             complement(19278..20186)
                     /locus_tag="VVR43_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU6149417.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            20250..20519
                     /locus_tag="VVR43_001049"
     CDS             20250..20519
                     /locus_tag="VVR43_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU6149418.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            20519..20899
                     /locus_tag="VVR43_001050"
     CDS             20519..20899
                     /locus_tag="VVR43_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU6149419.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            20988..21215
                     /locus_tag="VVR43_001051"
     CDS             20988..21215
                     /locus_tag="VVR43_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149420.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(21255..21980)
                     /locus_tag="VVR43_001052"
     CDS             complement(21255..21980)
                     /locus_tag="VVR43_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU6149421.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDSGPLGFQLLHPQYHVDKTYQVQVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            22142..23983
                     /gene="typA"
                     /locus_tag="VVR43_001053"
     CDS             22142..23983
                     /gene="typA"
                     /locus_tag="VVR43_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU6149422.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            24003..24257
                     /locus_tag="VVR43_001054"
     CDS             24003..24257
                     /locus_tag="VVR43_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU6149423.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            24622..24921
                     /locus_tag="VVR43_001055"
     CDS             24622..24921
                     /locus_tag="VVR43_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU6149424.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSIVSRWNGHSDKGEAPAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            24992..27013
                     /locus_tag="VVR43_001056"
     CDS             24992..27013
                     /locus_tag="VVR43_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6149425.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFIYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDIENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNILYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            27015..27656
                     /locus_tag="VVR43_001057"
     CDS             27015..27656
                     /locus_tag="VVR43_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149426.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            27760..29112
                     /locus_tag="VVR43_001058"
     CDS             27760..29112
                     /locus_tag="VVR43_001058"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU6149427.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIATD
                     KNTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMAAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            29114..30172
                     /locus_tag="VVR43_001059"
     CDS             29114..30172
                     /locus_tag="VVR43_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU6149428.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            30182..31402
                     /gene="divIB"
                     /locus_tag="VVR43_001060"
     CDS             30182..31402
                     /gene="divIB"
                     /locus_tag="VVR43_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU6149429.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEKSEEKVASSEADKEKEEKEESES
                     KEKEEQDKKLAKKAIKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKAFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKRLEEEQKKQEE
                     ESNRNQTTQRSSRR"
     gene            31635..32336
                     /gene="pyrF"
                     /locus_tag="VVR43_001061"
     CDS             31635..32336
                     /gene="pyrF"
                     /locus_tag="VVR43_001061"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU6149430.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            32370..33002
                     /locus_tag="VVR43_001062"
     CDS             32370..33002
                     /locus_tag="VVR43_001062"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU6149431.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            33182..33585
                     /locus_tag="VVR43_001063"
                     /pseudo
     CDS             33182..33585
                     /locus_tag="VVR43_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            33681..34445
                     /locus_tag="VVR43_001064"
     CDS             33681..34445
                     /locus_tag="VVR43_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149432.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            34445..35197
                     /locus_tag="VVR43_001065"
     CDS             34445..35197
                     /locus_tag="VVR43_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149433.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            35207..35905
                     /locus_tag="VVR43_001066"
     CDS             35207..35905
                     /locus_tag="VVR43_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149434.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            35902..36549
                     /locus_tag="VVR43_001067"
     CDS             35902..36549
                     /locus_tag="VVR43_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149435.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(36629..37494)
                     /locus_tag="VVR43_001068"
                     /pseudo
     CDS             complement(36629..37494)
                     /locus_tag="VVR43_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(37506..38263)
                     /locus_tag="VVR43_001069"
                     /pseudo
     CDS             complement(37506..38263)
                     /locus_tag="VVR43_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(38264..>38447)
                     /locus_tag="VVR43_001070"
     CDS             complement(38264..>38447)
                     /locus_tag="VVR43_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glutamine ABC transporter permease"
                     /protein_id="HEU6149436.1"
                     /translation="LVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVC
                     YPISKLSTHLEKHWRN"
BASE COUNT        11793 a         6856 c         8526 g        11272 t
ORIGIN      
        1 gtactttgag aaacctgtgg ctatcttcct agtttacttt ttgattttta ttgagtataa
       61 gaggtctttc ctaagcagtt agaggagaat tttgctatac tgatactagt aagtggtaaa
      121 ggagcagagc atgacctaca caatcttaat cgtagaagat gaatatctgg taagacaagg
      181 tttgactaaa ctggtcaatg tagcagccta cgatatggaa atcatcggtc aggctgaaaa
      241 tggaaggcag gcttgggaat tgatccaaaa gcaggtgcca gatatcattt taaccgatat
      301 caacatgcct tatctaaatg gcatccagtt ggccagtctg gtacgagaaa cctatcctca
      361 ggttcatttg gtctttttaa caggttacga tgattttgat tatgccttgt ctgctgtcaa
      421 actaggtgtg gacgactacc tgctcaaacc cttttctcgt caggatattg aggaaatgtt
      481 ggggaaaatc aaacaaaaac tagacaagga agagaaagaa gagcagttac aagatttatt
      541 gactaatagg tttgaaggaa acatggccca gaaaatccag tctcatctgg ctgatagcca
      601 atttagttta aagtctttag ccagtgactt aggttttagt ccgacctatc tgagttcctt
      661 gattaagaaa gagttgggct tgccttttca ggattatctg gtgagagaac gtgttaaaca
      721 agccaagctc ttgcttttaa ctacagatct gaagatttat gagatcgcag agaaggttgg
      781 ttttgaagat atgaactatt ttacccaacg ttttaagcag attgcaggtg tgacacctcg
      841 tcagtttaag aagggagaag accgatgaag cgttcttctc ttttagttag aatggttatt
      901 tccatctttc tggtctttct cattctccta gctctggttg gaactttcta ctatcaatca
      961 agttcttcag ccattgaggc caccattgag ggcaacagcc aaacgaccat cagccagact
     1021 agccacttta ttcagtctta tatcaaaaaa ctagaaacca cctcgactgg tttgacccag
     1081 cagacggatg ttctggccta tgctgagaat cccagtcaag acaaggtcga gggaatccga
     1141 gatttgtttt tgaccatctt gaagtcagat aaggacttga aaactgttgt gctggtgacc
     1201 aaatctggtc aggtcatttc tacagatgac agtgtgcaga tgaaaacttc ctctgatatg
     1261 atggctgagg attggtacca aaaggccatt catcagggag ctatgcctgt tttgactcca
     1321 gctcgtaaat cagatagtca gtgggtcatt tctgtcactc aagaacttgt tgatgcaaag
     1381 ggagccaatc ttggtgtgct tcgtttggat atttcttatg aaactctgga agcctatctc
     1441 aatcaactcc agttggggca gcagggcttt gccttcatta tcaatgaaaa ccatgaattt
     1501 gtctaccatc ctcaacacac agtttatagt tcgtctagca aaatggaggc tatgaaaccc
     1561 tacatcgata caggtcaggg ttatactcct ggtcacaaat cctacgtcag tcaagagaag
     1621 attgcaggaa ctgattggac ggtgcttggc gtgtcatcat tggaaaagtt agaccaggtt
     1681 cggagtcagc tcttgtggac cttgcttggg gccagtgtca catctcttct tgtctgtctc
     1741 tgcttagtgt ggttcagtct taaacgctgg attgctcctt tgaaggattt gagagaaacc
     1801 atgttggaaa ttgcttctgg tgctcaaaat cttcgtgcca aggaagttgg tgcctatgaa
     1861 ctgagagaag taactcgcca atttaatgct atgttggatc agattgatca gttgatggta
     1921 gctattcgta gccaggaaga aacgacccgt cagtaccaac ttcaagccct ttcgagccag
     1981 attaatccac atttcctcta taacactttg gacaccatca tctggatggc tgaatttcat
     2041 gatagtcagc gagtggtgca ggtgaccaag tccttggcaa cctatttccg cttggcgctc
     2101 aatcaaggca aggacttgat ttgtctctct gacgaaatca atcatgtccg ccagtatctc
     2161 tttatccaga aacaacgcta tggagataag ctggaatacg aaattaatga aaatgttgcc
     2221 tttgataatt tagtcttacc caagctggtc ctacaacccc ttgtagaaaa tgctctttac
     2281 catggcatta aggaaaagga aggtcagggc catattaaac tttctgtcca gaaacaggat
     2341 tcgggattgg tcatccgtat tgaggatgat ggcgttggct tccaagatgc tggtgatagt
     2401 agtcaaagtc aactcaaacg tgggggagtt ggtcttcaaa atgtcgatca acggctcaaa
     2461 cttcattttg gagccaatta ccagatgaag attgattcta gaccccaaaa aggaacgaaa
     2521 gttgaaatat atataaatag aatagaaact agctaactcc cagtcaattc tgggagtttt
     2581 atgcgtaatt gggcaaactt tctaggttgt ctatcttgct aaaaacaaga aaaaacggta
     2641 tgatagaaga gtgacaacag aggtaacaga gatgaacgag acacagattc aaagagaaac
     2701 acgtcaggta gtggaagatg ttttagaaaa gaccaatttg aagcaggggg ccctttttgt
     2761 tttaggtcta tcttctagtg aggtgctagg tggtcagatt gggaaagaat ccagtcaaga
     2821 gattggtgag ctgatagtgg agactatctt gggtattcta ggtagtagag gtatccattt
     2881 agcagttcaa ggttgtgagc atgtcaatcg ggctctcgtt gttgaacgtc aggtggcaga
     2941 gcagtttggt ctggaaattg tcagtgtcca tcctactctt catgcaggag gttcggggca
     3001 gttggcagcc tttaagttta tgcaggatcc agttgaggtt gaatttatca aggctcatgc
     3061 tggattggat atcggagaca ctgcaattgg catgcatgtc aagcatgttc aggttccgat
     3121 tcgccctatt ttgagagaga ttggccatgc ccatgtaacg gcactggcta gtcgtccaaa
     3181 attaatcgga ggtgcgcgtg cgcactatcc gcaagatgct attaggaagt cttgagaatg
     3241 aataaaggag ataaaagtgt ttaaaaaaga ccgtttttca attcgtaaga ttaagggagt
     3301 tgtaggctct gtatttcttg gaagcctttt gatggctcct tctgtagtgg acgcagccac
     3361 ctatcactat gtaaataaag agattatttc acaagaagct aaagatttaa ttcagacagg
     3421 aaagcctgac aggaatgaag ttgtatatgg tttggtgtat caaaaagatc agttgcctca
     3481 aacagggaca gaagcatctg ttttgacagc ttttggtttg ctgactgttg ggagcttgct
     3541 tttaatctac aagagaaaga aaattgctag cgtctttcta gttggagcta tgggattggt
     3601 agttcttcct agtgcagggg ctgtagaccc agttgcgacc ctagcactgg ctagtcgaga
     3661 gggtgttgtt gaaatggagg gctatcgcta tgttggttat ctatcaggtg acatcctcaa
     3721 aacgcttggc ttggacactg ttttagaaga aacctcagca aaacctggag aggtgactgt
     3781 agtcgaagtt gagactcctc aatcaacaac aaatcaggag caagctagga cagaaaacca
     3841 agtagtagag gcagaggaag ctccaaaaga agaagcacct aaaacagaag aaagtccaaa
     3901 ggaagaacca aaatcggagg taaaacctac tgacgacacc cttcctaaag tagaagaggg
     3961 gaaagaagat tcagcagaac cagctccagt tgaagaagta ggtggagaag ttgagtcaaa
     4021 accagaggaa aaagtagcag ttaagccaga aagtcaacca tcagacaaac cagctgagga
     4081 atcaaaagtt gaaccaccag tagaacaagc aaaaggccca gaacaacccg tgcaacctac
     4141 acaagctgag caaccaagga taccaaaaga ttcatcacaa ccagaagatc ctaaagaaga
     4201 taggggagcg gaagagacac cgaaacaaga agatgaacag ccagcagaag ccccagaaat
     4261 caaggttgaa gaaccagtag aatcaaaaga ggagactaaa acagctaagg ggacgcaaga
     4321 agaaggcaaa gaaggtcaag caccagtaca agaagtaaac ccagaatata aagtaacaac
     4381 aggtacagtt gagaagtcta ccgaaagtga attagatttc acaacagaag tagttccgga
     4441 tgacacaaaa tatgtagatg aagaagttgt tgaacgtcaa gggtctaaag gagttcaagt
     4501 tacgaaaaca acttacgaaa cagtggaagt tgtagagaca gacaaagtcc tttctacaac
     4561 tacagaagtg aaaactcctg ctgttcctaa agtcgttaaa aaaggaacaa aaccagttaa
     4621 aggaacagca gtcgaaacaa gagaagaagt cattcctttt gctacgaaag aacaagaaga
     4681 tgacacttta aaacgcggaa caagacaagt agctcaagaa ggtgtaaatg gtaagaaaca
     4741 aattactgaa acctataaaa caattcgcgg agaaaaaaca aacgaagctc caacagtaga
     4801 agaaacagtt ctccaagcac ctcaagatga gattatcaaa aaaggcacaa aaggtttaga
     4861 aaaaccaacc ttagaatggg ttaaaacaga taaagatgtc ttgaagaaga gtgcgacagc
     4921 cagttataca ttgaataaac cagatggggt agaaatcaaa tccatcaaag tagctctaaa
     4981 agataatact ggaacagtta ttaaagaagt aacggtagaa gaaaataact taaacgctac
     5041 tttagacaac ttgaaatatt atcaaggtta tacactatcc acaaccatgg tctataatcg
     5101 aggcgaaggc gaagaaactg aaacgttaga agataaagaa gttcagttag accttaaaaa
     5161 agttgaaatc aaaaacatca aagaaactag cttgatgagt gtggatgatg ctggtgttga
     5221 aacagataag agcttactta ctgaaaaacc gacagacgtt gctccacttt acctacgagt
     5281 gacaactcat gataacaaaa caacaagact ggcagtaagt tcagttgaag aagttgttgt
     5341 tgatggaaaa acattgtaca aagtggtagc taaagctcct gacttagttc aacgtagaga
     5401 agatgataca ctaagcgaag agtatgtaca ttactttgaa aaacaattac caaaagtaga
     5461 taatgtgtac tatagcttta acgagttaat tacagatatg caaaaaaatc ctactggtac
     5521 attcaaacta ggtgcagatc ttaatgcagc gaatactcca actccaagta aatcatatgt
     5581 aacaggtgaa tttaaaggta aattatcaag tgttgatggt caacattata cgattcacaa
     5641 tactgcgcgc ccattattta acaatattgt tggtggtacc gttaaaaata ttaatcttaa
     5701 caatgtaaat atcgatatgc cttgggctga tcaaattgca tctgtagcaa atgtgatcaa
     5761 aggtggtagc cttattgaga atgttaaagt caaaggtaat gtgctcggca gaaactgggt
     5821 atctggtttc attgataaaa ttgacagtgg tggtagatta gttaatgttg catttattgg
     5881 taatgtaact tctgttggag atggggataa attcttaaca ggtattgttg gagaaaactg
     5941 gaaaggatat gtcgaaaaag catacgttga agctaatatt aaaggtaagc gagctaaagc
     6001 tgctggtata tcttattggt cgcaaaatag cggagataat aatgctgtcg gtagagatgg
     6061 agcaattaag aaatctgtcg ttaaaggttc aatagatgta gaaaaaccaa ttgaagttgg
     6121 tggcgctgtt ggaagtttaa attatcttgg ttatatagaa gacactgttg ctatgatgaa
     6181 agttaagaac ggtgaaattt tctacggttc gcatgatatc gataccgatc catattacac
     6241 aggagaacga gtaaatagaa atttcattgt tgacggtgta agtgaaggta aatcttcgta
     6301 tacatactct aaacaacaaa agcgtattaa atcaatatct caagaggaag cagataagaa
     6361 aattaaagaa ttgggtatca cagcagataa atttacaatt atcgatccaa ttgtaaataa
     6421 acttaacaac atcaaacaaa aagctgatac ttataaagat actcaagatt acaaagcaga
     6481 ccgtgaactt acttatcgta atatcgaaaa acttcaacca ttctacaata aagagtggat
     6541 tgtagaccaa ggtaataaag ttccatcaaa ttctaaatta ttaactacag aagtattatc
     6601 tgttacaggt ataaagagcg gtcaattcgt aactgatttg tcagatattg ataaaattat
     6661 gattcactat tctgatggag caaaggaaga attgaatgtt actcgtcaag aatcaaacgt
     6721 tcaacaagtg cgtgagtaca gtatcacaga tttagatata ctctatacac caaatatggt
     6781 tgagaaagat cgcgctcagt tgatgactga tgtaaagtct aagctatcta gtgtagaatt
     6841 agagtctgat ggagtgcgtc aacttctcgt taagagagat actaagaaag atgcgaatgc
     6901 aaatagtgta ggtcgtcaaa atggatacat tagagattta ttccttgaag aaagtttctc
     6961 tgaagttaaa gcaaatcttg acaaattggt aaaacagata cttgaaaatg aagatcatca
     7021 actcaacgat aacgaattag ctgaacgtgc tttactgaag aaagttgaag ataataaagc
     7081 taaaatcatg atgggactgg catacttaaa tcaatattat gcttttaaat acgatgagtt
     7141 atcaattaaa gatattatga tgtttaaacc tgatttttat ggtaagacag caagtgttat
     7201 tgatagattg attaatattg gttctgcaga aaataatcta aaaggagata gaacgcaaga
     7261 tgcttatcgt ggtataattt caggggcaac aggtaaaggt agtttacatg acttcttgac
     7321 ctacaatatg aaattattca caaatgaaac agacataaat gtttggttta agaaagctat
     7381 tgaaaagaat gcttatgtag ttgaacaacc atcaacgaac cctgcatttg ccaacaaaaa
     7441 atatcgtcta tacgaaggaa ttaataatgg gcaacatggg cgcatgattt tacctcttct
     7501 taacttgaaa aatgcacatc tatttatgat ttcaacatac aacactatct cgtttagttc
     7561 atttgaaaaa tatggcaaag acacagatga aaaacgtgaa aagttcaaga gtgagatcaa
     7621 taaacgtgct aaagagcagg ttaattactt agatttttgg tcacgtcttg ctactgataa
     7681 tgtccgtgat aaacttctta agagtcaaaa tgtagttcca actcctgtat gggataatca
     7741 taatagcccg aacggatggg ctagtagaca tggtcatata gatgggaaac cggattatgc
     7801 tccaattcgt gagttctttg ggcgaatcaa taagtatcat ggttacaaat atggatatgg
     7861 cgcatatgca tatatttttg cagcacctca accgatggat gcagtttatt tcgttatgac
     7921 agatttaatt agtgactttg gaacatctgc atttacacat gaaactactc acgttaatga
     7981 tcgtatggct tactatggtg gtcattggca tcgtgaaggt acggatcttg aagcatttgc
     8041 tcaggggatg ttacaaacgc catcggtatc aaatccaaac ggagaatatg gcgcattagg
     8101 tctaaatatg gcgtatgaac gtcaaaatga tggaaatcaa tggtataaca caaatccaaa
     8161 cgaccttaca actcgtgcag aaattgataa ctacatgaaa ggtttcaacg atacattaat
     8221 gcttcttgat taccttgaag gagaagctgt cctcaataaa gcaaatcaag atttaaacaa
     8281 cgcttggttc aaaaaagtgg ataagcaact tcgtggagct agtacgaaga accagtatga
     8341 taaagttcgt gatttaacgg cagatgagaa aaatatcact ctaaattcag tagatgattt
     8401 agttgataat aattttatga cgaaacacgg acctggaaac aatgtatatg atccaactgg
     8461 gttcggaacg gcctacgtga ctgtacctat tactgcaggt atttatggag gtaacacaag
     8521 tgaaggtgct cctggttcta tgtcattcaa acataacaca ttcagaatgt gggggtacta
     8581 cggatatgaa aaaggattct taaactatgc ttctaacatg ctgaaaaatg agtctagaca
     8641 ggctggtcac aatactctag gtgatgattt catcattaag aaagtttctg ataataaatt
     8701 cagtacattg gaagattgga agaaagcata cttcaaagaa gttgtagata aagctaaagc
     8761 aggatttaac cctgttacaa tcgacggtac tacatatagt agttacgatg acttgaagaa
     8821 cgcatttgct gcagcagttg aaaaagataa agctactctt aaaaatggat cagttaaatc
     8881 tgacaatact gttgcactta aagagaaaat atacaaaaaa cttcttcaac aaacagatag
     8941 ctttaaaact tcaatcttta gataatcgaa atctctcatc tgctttgcgg atgagggttt
     9001 tcttatttta tgctatactt aaggtatgca tagaaaaaca gtgattgatt ttaggacttt
     9061 aggggagaga tataccttta cccagcctat taaagagttg aaaacgagaa atgtagaaga
     9121 agtggcagat ttgctggcac aagtggaaag ctaccaagag caaggttatt atgtggtggg
     9181 gtatgtcagc tacgaggctg cacctgcttt tgaggagaaa ttaacagttc acaaggttcc
     9241 tctactgggc gagtacttgc tttactttac tgttcacgat agggtagaga cctcccctat
     9301 tcctctgact tatgaggata ttgatttgcc ctcaaattgg caggaagtga cgtctgcagc
     9361 agactatgaa aaggccattg cccagataca ccatcacttg aggcagggag acacctatca
     9421 ggtcaactac accgtccaac tcaagcaaaa gttaagtgcc aatccttttg ctatctacaa
     9481 tcgtatggtg gtagagcagg aggcgggcta caatgcctac gtggaacatg acgagatggc
     9541 agtgatttcc atgagcccag agctcttttt tgagcaaaat gatcgcgagt tgacaacacg
     9601 accaatgaag gggacgactc agcgtggggt aactgaccaa gaagatcttg aacaggccag
     9661 ttggttggaa caggatccca aaaatcgctc tgaaaatatg atgattgtgg acctcttgcg
     9721 caatgatatg aaccgtattt ctgaagttgg gagcgagcac gtggagcgtc tgtgtcaggt
     9781 agagcagtat tcaactgttt ggcagatgac ttcgaccatc aagagtcagt tgcgagagga
     9841 tgtggacctt gttgaaatct tccgctcact ctttccttgt ggttccataa cgggtgcacc
     9901 gaaaattgcg acaatggaga ttatcaagga cttggagcct caaccgcgtg gagtctactg
     9961 tggaacgatt ggtctcttgc ttccaaatgg acgacggatt tttaatgtgg ccattcgtac
    10021 cattcaactt cacaaagatc aagccattta tggagttggc ggagggatta cttgggatag
    10081 cacatgggaa tctgaatacc gagaggttca tcaaaaggca gcagttcttt atcgtaaaca
    10141 agctcgcttc caactgatta cgacagggaa aatcagccag aagaacctgc tgtttgaaga
    10201 tcaacatctg gaaagactga gaaaagccag tcgttatttt gcctttcctt ttgatgcaga
    10261 agacttggga cacaagattg aggaagagtg tcaggattgt gaagctaatc gagattaccg
    10321 cttgcgaatc agccttagca aatctggaga gatagaagtc aatcgtcaag tattaacccc
    10381 tctcagtaca agcttttgtc aggcccaagt ctgtcttcag gaagctgctt tgaatcaatc
    10441 ctttacctac tttaaaacca ctcaccgacc gcatttgagc ctaggagaac aagagaagat
    10501 ttaccacaat aagtcaggag aactgcttga aacctctata ggaaatttgg ttctgaaaat
    10561 cgctggaaaa ctctacacac cgcctatccg acttggaatc ttgccaggaa tttaccgtca
    10621 gcatttgcta gaaacaggac aggtagaaga gaaagtcttg accttggcag atttagccca
    10681 agcagaagct atttacggct gtaatgcagt gagaggcttg tatgaactaa gccttgagga
    10741 gaactagatg aaattgatat ttttgcatgg gttagggcag tcagcagagt cttggaaaga
    10801 agttcggaat ctactgacag attatccttc tgaggctatc gagttatttc cttctggagt
    10861 tagtaactat caacaagcta aagagcgagt ttatcagcac ctagctcaag agacagaacc
    10921 ttttgttttg attggattgt ccttaggtgc tgccctgaca ctagaacttt ccagttacga
    10981 tttaccaaat cttcgagctt tgattctgtc aggatgcccg cttaaattag cagggaatat
    11041 cctattttat cttcaattgc tgatttttaa actacttccc aaaagagtat ttgaaaaaca
    11101 gggagcagac aagactctta tggtcggagt ttctgaggaa ttgaagacac ttgatttaac
    11161 ggatatagca gggacttgct cctatccaac cttactaatt tgtggcagca aagataaacc
    11221 gaatcttagt tctatgaaag ctctccatag actgttaaca gattcgcagt ttcagatcat
    11281 tcctgatggc cctcatgtct tgaataaggc aaaaccaaag gagtttgtag aaaagaccag
    11341 aagtttcctt gaattgctga aataagtttg ataaaataat attgaaatcg atatcataat
    11401 tatgggagaa agaaatgaat aaacgtctat ttttaaaaat gagtctggtg acgttgccaa
    11461 ttttagcctt gttttcacaa ccagttttgg cggaagaaaa catccatttt tcgagctgta
    11521 aggaagcttg ggcgaatggc tattcggata ttcacgaggg agaacctggt tattctgcca
    11581 agttagaccg tgatcatgat ggtgtggctt gcgaattgaa aaatgctcct aagggtgctt
    11641 ttaaagcaaa acaagcggct acaactcaaa ctgatacaac ttcatccaca gcaagtggtt
    11701 gggttaagca ggacggttct tggtactatt ttgatggaaa tggaaatcta gtgaaaaatg
    11761 catggcaggg aaactattac ctgaaagctg atggtaaaat ggcacagagt gaatggattt
    11821 atgactcttc ttatcaagct tggtattact tgaaatcaga tggttcatat gctcgcaatg
    11881 catggcaagg aaactactat ttgaaatcag atggtaaaat ggctaaaggt gaatgggttt
    11941 atgatgccac ctatcaagct tggtattact tgaaatcaga tggttcatat gctcgcaatg
    12001 catggcaagg aaactactat ttgaaatcag atggtaaaat ggctaaaggt gaatgggttt
    12061 atgatgccac ctatcaagct tggtattatt tgacatcaga tggttcttat gcttacagta
    12121 catggcaagg aaattactat ctaaaatcgg atggtaaaat ggctgtcaat gaatgggttg
    12181 atggtggacg ttattatgtt ggcgctgacg gagtttggaa ggaaggtcaa gcaagtacag
    12241 cttcttctag taatgatagc aatagtgaat attctgctgc tttaggaaag gcaaagactt
    12301 ataactcact attccatatg tcaaaaaaac gcatgtatag acaattaact tctgattttg
    12361 ataaattttc aaatgatgca gctcaatatg ccattgatca tttagatgat taacagatac
    12421 tggtaggcga aaaaattcct tataattcat ttacgcaaac ctttgcataa gtgaatggat
    12481 tttgatatac tagtactgta agcattttca attactacac aatgaaaaag gagaatatga
    12541 tgagtcaaaa gattattggg attgaccttg gcggaacttc tatcaaattt gcaatcttaa
    12601 caacagcagg agaaatccaa ggaaaatggt caatcaagac caacattttg gatgagggaa
    12661 gtcatatcgt tgatgatatg attgagtcta ttcaacatcg tttggacttg cttggattgg
    12721 cagcagcgga cttccaaggc attggaatgg gatcaccagg tgtggttgac cgtgacaaag
    12781 ggactgttat cggtgcctac aacttgaact ggaaaaccct tcaaccaatc aaacaaaaga
    12841 ttgaaaaagc tttgggcatt ccatttttca tcgataatga tgccaacgta gcagctcttg
    12901 gtgagcgctg gatgggtgct ggtgataacc aaccagatgt tgtctttatg acactcggta
    12961 ctggtgttgg tggtggtatt gtcgcagaag gcaaattgct tcatggtgtt gctggtgcag
    13021 caggtgaact tggtcatatc actgttgatt ttgaccaacc aattgcatgt acttgtggta
    13081 aaaaaggctg tcttgagaca gtcgcttctg caacaggaat tgtcaatttg actcgtcgct
    13141 atgccgatga atacgaaggc gatgcagcct tgaaacgctt gattgataac ggagaagaag
    13201 taactgctaa gactgtcttt gatctcgcaa aagaaggaga cgaccttgct ttgattgttt
    13261 accgtaactt ctcacgttac ttgggaatcg cttgtgctaa cattggttca atcctaaacc
    13321 catcaacaat cgtcatcggt ggtggtgtgt cagctgcggg agaattcctt ctacaaggtg
    13381 ttcaaaaagt ttacgatgaa aatagtttcc cacaagtacg cacatctact aaattagctc
    13441 ttgcaactct aggaaatgac gctggagtta tcggagcagc atcacttgta ttgcaataag
    13501 ataatgagag aggaaaatgc taacctagag ttagtaatgt tcctctttta ttttttatgc
    13561 tatactagtt aggacaatga atgaggtgag agtaaatgac aaaagcagat acgattttta
    13621 aagagaatat tgaacgcatt ctaaaggaag gtgttttctc agagcaggct cgtcctaagt
    13681 acaaggatgg gactgttgct aattccaagt atgtaactgg tgccttttcc gagtacgact
    13741 tatctaaagg agaatttcct atcacaacct tgcgtcccat tgcaatcaaa tccgccatca
    13801 aagaagttct ctggatttac caagaccagt caaatagctt agaagtgctt aatgacaagt
    13861 acaatgttca ctactggaat gactgggaag ttggagacac gggaaccatt ggtgagcgct
    13921 atggtgccgt tgttaagaaa cacgacatta tcaataagct tctcaaacag ttggaaacca
    13981 atccttggaa ccgccgcaat attatttctc tctgggatta ccaagctttc gaagaaacag
    14041 atgggctgct cccgtgcgcc tttcagacca tgtttgatgt tcggcgtgtt gatggggaaa
    14101 tctatctgga tgcgaccttg acccagcgct ccaatgatat gctggtggcc caccacatca
    14161 acgctatgca gtatgtggct ttgcagatga tgattgccaa acattttggc tggaaggttg
    14221 ggaagttctt ctacttcatc aacaacctcc atatctatga taatcaattt gaacaagctc
    14281 aggaattgct ccgtcgggag ccgtcaaact gccaaccacg cttggtttta aatgttcctg
    14341 atgggactaa tttctttgat atcaaagcag aagattttga gttggtggat tatgaccctg
    14401 ttaagccaca gttgaagttt gacctagcta tttaaaagaa tagaaaaaga agttgagaat
    14461 aatcccaact tcttttgttt cttaacgtga tacgcggcga cgagctgctt ttttacggtt
    14521 ttcttcgatg aaagctgctt tttgctcttc tggttcgatt actttctttt taaatgcgta
    14581 tactgcacct gcaacggcag cgacagttcc tgcgacacct gttacaagac ctttagcgaa
    14641 tcctttagcc atgagtcttc ctcctttata ttctcaatca gccagcctcc tcaagaggtc
    14701 acatttttct gactgacctt tttgtgttat aataatagta acgaaaaaat gggaattttt
    14761 caaggaaaaa agatgaaaac aaaaataatt gtgattgttg gaccgactgc tgttggaaag
    14821 acggctctag ctattgaagt tgcaaagcgt tttaatggcg aagtggttag tggagatagc
    14881 caacaagtct atcgaggact tgatattggg acggctaagg ctagtccaga agagcaggca
    14941 gctgttcttc atcatttaat cgatgttaga gagataaccg agtcttactc ggcttttgat
    15001 tttgtttcag aagctaagat gactattgag gatattcaca gccgtggcaa gctagccatt
    15061 atcgccggtg ggactggact ttatatccag agcttgctag aaggttacca cctaggtggg
    15121 gagactcctc atgaggagat tttagcttat cgagctagtt tggagccata ttcagatgag
    15181 gaattagccc atttggtgga gcaagcaggc cttgagattc cccagtttaa tcgtcgtcgt
    15241 gctatgcgtg ccttagaaat tgcccatttt ggtcaggatt tggaaaatca agagaccttg
    15301 tatgaaccgc tgattatctg cttggatgat gaacgtagtc aactttatga gcgtatcaac
    15361 caccgagtgg atttgatgtt tgaggctggg cttttggatg aggccaagtg gctgtttgac
    15421 cattccccta atgtacaggc tgctaaagga attggctata aggaactctt tccttatttc
    15481 cgtggagagc agacctttga ggaagctagt gagagtctta aacaggcgac ccgtcgtttt
    15541 gccaagcgtc agctgacctg gttccgtaat cgcatgcagg tcacctttta tcagattgga
    15601 gaatctggtg tacaagaccg cattttaagc cagatagagg agtttttaga tgattgaaac
    15661 ggagaaaaaa gaggagcgag tcctgctgat tggtgtggaa ttgcagggta tggacagttt
    15721 tgacctctcc atggaagaat tggctagttt agcgaaaacg gcaggggcag tcgttgtaga
    15781 tagctacaga caaaaacgtg aaaaatatga ttccaagacc ttcgtcggct ctggtaagtt
    15841 ggaagagatt gcgcttatgg tggatgcaga agaaatcact actgtcatcg tcaacaatcg
    15901 tctgacccca aggcagaatg tcaatctaga ggaagttctc ggtgttaagg tcattgaccg
    15961 tatgcagttg attttggata tctttgccat gcgggctcga agccatgaag ggaagctcca
    16021 agtccaccta gcccaactca aatacctttt gcctcgcttg gttggtcagg ggattatgct
    16081 cagccgtcag gcagggggaa ttggttcccg tggtcctggt gaaagccagc tggagctgaa
    16141 ccgtcgtagc gttcgcaatc aaatcacgga tatcgagcgc cagctcaagg tggttgagaa
    16201 aaatcgggcg actgtcagag aaaaacgttt ggagtctagc acctttaaga ttggtttgat
    16261 tggttatacc aatgctggga aatcaactat catgaacatc ttgaccagta agacccagta
    16321 tgaagcagat gagctctttg cgactctgga tgcgacaacc aagagtattc atctgggagg
    16381 caatctccaa gtaactttga cagataccgt tggctttatt caagatttgc cgacagagtt
    16441 ggtgtccagt ttcaagtcaa ccttggaaga aagcaagcat gtggaccttc tggttcatgt
    16501 tatcgatgct agcaatcctt accacgagga gcatgaaaaa acggttctct ccatcatgaa
    16561 agacctggac atggaagata ttcctcactt gacgctttat aataaagcgg atttggtgga
    16621 ggatttcacg cctacccaaa cgccatatac cctcatttct gccaagtctg aggacagtcg
    16681 tgaaaacttg caagcattat tgctagataa gattaaggaa atttttgaag catttaccct
    16741 gcgagtgcct ttttcaaagt cctacaagat tcatgattta gagagtgttg caattctgga
    16801 agaacgtgat tatcaggaag acggcgaagt gattacaggc tacatttccg agaaaaataa
    16861 atggaggtta gaagaatttt atgactgata ttaaaacttt ggctctaaag tatggaggtt
    16921 atacaagtct ggacaaggtc tatctggatc agcttctagc tggtaaaaca gagcaggagc
    16981 agttaacact tattacacct ccgccaagtg ttgttaatgc ctactttgca gaactctatc
    17041 agaaaaaaag tcctcaggct gcgacggatt attttgcaga actcagtcag gaactgaatc
    17101 tttacaatac tgaaccaagt ttcaccctag aaaataagcc ttttattcgg cttaatctgt
    17161 ctggtaaatc ctttggtttt tgttatgaga gtgacggctt tggtcggatt ttctctgaaa
    17221 atgaggagaa aatctcggat gacttgctct ttgaaattgc gcaaattttc tcccatcaat
    17281 tagtctttga agagtctggt aagatttaca tgaagcctgt caaggacgag gaagttgtca
    17341 gcctagaaag tctcacagct ttgactgatt tggaaagatt ggctgatggt cgaaaacgtc
    17401 tcaaaggcta cagccaagag gatttattgc aagaagctgc tgctttttct ggcaaacgct
    17461 atttccgatc ggaaaaccgc acagccatgt tatatattga ttaattagaa agtatcgaat
    17521 ggatattcaa tttttaggaa cgggggctgg tcagccctct aaagcccgca acgtttcaag
    17581 tctcgccctg aaacttttgg acgagattaa cgaagtttgg ctctttgact gtggagaagg
    17641 tacgcaaaat cgcattctgg aaaccacaat tcgaccacgt aaggtcagca aaatctttat
    17701 tacccatctg catggagacc acatttttgg tttgccaggt ttcctttcta gccgtgcctt
    17761 tcaggccaat gaagagcaga cagatttgga aatctacgga cctcaaggaa tcaagtcatt
    17821 tgtcttaacc agccttcgtg tgtcaggttc tcgtctgccc taccgcattc atttccatga
    17881 gtttgaccaa gattctctgg gtaaaattct tgaaaccgat aaattcactg tgtatgcaga
    17941 ggagctggac cacactattt tctgtgttgg ctatcgtgtc atgcaaaagg atctagaagg
    18001 gacgctggat gctgaaaaac tcaaggctgc tggtgttccg ttcggcccgc tttttggtaa
    18061 aatcaaaaac ggccaggatc ttgttttgga agacggaact gaaatcaagg cagcagacta
    18121 tatctcagcg ccacgtccag gtaagattat cactatttta ggagacactc gaaaaacgga
    18181 tgccagtgtg cgtctggctg tcaatgcaga tgtcctagtt catgagtcca cttatggcaa
    18241 gggtgatgaa aaaattgctc gtaaccatgg tcactcaact aatatgcaag ctgcacaagt
    18301 agcggtagaa gcaggtgcca aacgcctcct actcaaccat atcagtgccc gtttcctctc
    18361 aaaagatata agcaaactca agaaggacgc tgccacaatt tttgaaaatg tccatgtggt
    18421 caaagacttg gaagaagtgg aaatctagca gtcacagaaa ggataagtat gcctactatt
    18481 ctcattaccg gagctagcgg tggtctagct caagaaatgg tcaaactcct gcccaatgac
    18541 caactcatct tgcttggtag aaataaggaa aaattagccc aactctacgg aaattattcc
    18601 catgcagaat tgattgaaat tgatattacc gacgattcag ccctagaagc tctggtaact
    18661 gatctttatc tccgctatgg caagattgat gtcttgatta acaacgctgg ttacgggatt
    18721 tttgagggat ttgaccagat tgctgataaa gatattcacc agatgtttga ggtcaatacc
    18781 tttgccctga tgaatctgtc tcgtcacctt gcggctcgta tgaaggaaag cagcaaaggg
    18841 catatcatca acatcgtcag catggcaggt ctaatagcta ctggcaagtc tagtctttac
    18901 tcagcgacca agtttgcggc tattggtttt tcaaatgctc tgcgactcga acttatgccc
    18961 tatggagtct atgtgacaac agtcaatcca ggtccaatcc gaacaggatt ttttgaccaa
    19021 gctgacccag atggaactta tcttaaatcg gttgaccgct tcctcttaga ggcagatgca
    19081 gtggctaaaa agattgtcaa gattatagga aaaaataaac gagaactcaa tctcccgatt
    19141 ttgttgaacc tagcccataa gttttatact ctctttccca agctagctga taagttggca
    19201 ggggaaactt ttaattataa gtaaaaagaa ccaatgtgca ggttgttgct agcctacata
    19261 ttggttctta tcatttctca actatcaaac tgaacttctt ctagtagata gtcgataaag
    19321 cgttcgccca tcttagatag gctggttttc tcatgctgga tatagaccag ctcaatcggg
    19381 tcatcaatat ccagtgggat agaaacgata ttgtctccgt ttaggttgct gttcaaaatc
    19441 cctgtcgcaa tggtataacc atccaaacca atcaagagat taaagagggt ggcacggtca
    19501 ctgaccacaa tggatttctt gtggtgttct tgagaaagaa tctcttctga aaagtagaag
    19561 gagttgtgcg tcccttggtc atagctgagg taagggaaat tctccaaatc agacagtttc
    19621 accttgtctt tctttgccag agggttggtc ttgctgacaa agatatgcgg ttgcgctgtg
    19681 aagagatggt gggctagtag gtgattgtca tccagcatct tggttaaaac atcacggttg
    19741 taactgttta agaagaggac cccgacctca ctgcggaagt tcttgacgtc gtcgataatc
    19801 tcccaagtcc gagtttcacg aaggaaaagc tcgtatttct ccatatcgct tttcttgagc
    19861 aaagagacaa aggcattgac cacaaaggca tagtgttgag acgaaacgct aaagagttcg
    19921 cggtgggcga caggattttt atagcgttcc tccagaagct gagtttgctc gacaacctga
    19981 cgggcataag agagaaactc catcccatca cgggtcaagg tgattccctt gggattgcgg
    20041 ataaagatct caatgcccat ttcattttcc aaatctctca cagcattgga aagacttggc
    20101 tgagtgataa agagttgctt ggctgcctca ttcatagagc cagtttcgac gattttgata
    20161 atataatgta attgttgaat tctcatgttt ttattgtacc acacttgcct tagaatcgcc
    20221 aaagaagata ggaaaataag gagcattgtg tgagtctctt cttgaaaaaa acacaaaatt
    20281 ttgctagaat gagtcttatg aaaacattct atgatgtgca gcaattcctc aaacgatttg
    20341 gtattattgt ttacatggga aaacgcttat atgatattga actgatgaag ttggaactat
    20401 ctcggattta cgatgcaggg ttgatggata aattagacta tctagaggca gaagcagttc
    20461 ttcgcagaga gcacaaggta gaattggatt atattgagaa aaatggagaa aagaactaat
    20521 ggttacttgg attttgtggg cacttatact agcaatgttg gcgtggatgg gctttaacta
    20581 tcttcgtatt cgtcgtgcgg ctaaaattgt ggacaatgag gagtttgaag ccttgattcg
    20641 tacgggtcaa ttgattgatt tgcgcgaccc agcagaattc cacagaaaac atatccttgg
    20701 tgcacgcaat attccttcaa gtcagttgaa aactagtctt gcagcccttc gtaaagataa
    20761 acctgtcctt ctctacgaga accaacgtgc gcaacgagtt acaaatgcag ctctttactt
    20821 gaaaaaacaa ggtttttctg agatttatat cctttcttat ggcttggatt cttggaaagg
    20881 gaaagtgaag actagctaac cttatttcca aattagtcga atgataggat gaagctattg
    20941 ttttatagta taattaattt gtataaaatt taaagagttc ttagaacatg aaagaaaaga
    21001 agaaaaatcc actttttgtg ggtatcttgt cgattattct tggtttgtta tttccaattg
    21061 taggcttgat tttgggtatc ataggattgg tcttggctat ttcataccaa aaagagtcac
    21121 aattagacta taaaatagaa aagattctta atatcttagg aattgtgatt tctgtagtta
    21181 actggattgt agcaatcgcc ttaatttttc ggtaaataaa agaaaaaagc tttagtttta
    21241 aagctttttt tgttttatcg actcatctct aaatagtttt taatgatttg taactctttt
    21301 tggttcaaag ggcggtagtt actttctgct aaatctgggt tcaatgtgaa gtccccaaat
    21361 tggattcttt tgaggctagt caccttaaca ccaaccgaga ggaacatttt cttgatttga
    21421 tgaaattttc cttctgaaat ggtgatagag gcttgactga gggagggact tgcagataga
    21481 atctctagtt ttgcgggttt acagacagta ccatctaaaa agacaattcc cttttgaaag
    21541 gcttggatat ggtcaggtgt tagaagtcca ttaacctgga cttggtaagt cttatcgaca
    21601 tgatattggg gatggaggag ctgaaagccc aagggaccgc tatcggtcaa gaggaggagt
    21661 cccgttgtat ctcggtccag tcggccaacg gcatagagct tgtcagactg gatgtcagat
    21721 ggaagcaggt ccatgacggt cggaagttcc ttgtctttgt tggctgtaac gacaccagca
    21781 ggcttatgaa gcataagata ggtgtgttca tagccttgaa tgattcgatc ctgaaaaagg
    21841 agttcttgta gtcctgtatc gatattttga gctagggatc gggctgggca accatcgact
    21901 agaatttccc ctttgagtaa ggcttgtttc atggcctttc ggctgatttt ttcttgagct
    21961 aataaattat ctaaacgcat actgtgccta tcttatcata agtcgcttgc tttgaaaagg
    22021 cttgacgtga aaagaaaagt ggagtgaaaa catttacact tgcttgagtt atgttattta
    22081 cttgaaatta tggtataatc gttcagttag aaaataaatt ttgaatatta tagaggaaat
    22141 catgacaaaa ttaagagaag atatccgtaa cattgcgatt atcgcccacg ttgaccacgg
    22201 taaaacaacc ctggttgacg aattattgaa acaatcagaa acgcttgatg cacgtactga
    22261 attggcagag cgtgctatgg actcaaacga tatcgaaaaa gagcgtggga ttaccatcct
    22321 tgctaaaaat actgccgttg cttacaacgg aactcgtatc aacattatgg acacaccagg
    22381 acacgcggac tttggtggag aagttgagcg tatcatgaaa atggttgacg gtgttgtctt
    22441 ggtcgtagat gcctatgaag gaaccatgcc acaaactcgt ttcgtattga aaaaagcctt
    22501 ggaacaagac cttgtcccaa tcgtggttgt taacaaaatc gataagccat cagctcgtcc
    22561 agcagaagta gtggatgaag tcttggaact tttcatcgag cttggtgcag atgacgacca
    22621 gcttgatttc ccagtggttt atgcttcagc gatcaacgga acttcttcat tgtcagatga
    22681 tccagctgac caagaagcga ctatggcacc aatctttgac acgattatcg accatatccc
    22741 agctccagta gataactcag atgagccttt gcagttccaa gtgtcacttt tggactacaa
    22801 tgacttcgtt ggacgtatcg gtatcggtcg tgtcttccgt ggtacagtta aggttgggga
    22861 ccaagttacc ctttctaaac ttgacggtac aactaaaaac ttccgtgtta caaaactctt
    22921 cggtttcttt ggtttggaac gtcgtgaaat ccaagaagcc aaagcgggtg acttgattgc
    22981 cgtttcaggt atggaagaca tctttgtcgg tgaaaccatc actccgacag atgcagtaga
    23041 agctcttcca atcctacaca tcgatgagcc aactcttcaa atgactttct tggtcaacaa
    23101 ctcaccattt gctggtaaag aaggtaaatg ggtaacttct cgtaaggtgg aagaacgctt
    23161 gcaggcagaa ttgcaaacag acgtttccct tcgtgttgac ccaactgatt caccagataa
    23221 atggactgtt tcaggacgtg gagaattgca cttgtcaatc cttatcgaaa caatgcgtcg
    23281 tgagggctat gaacttcaag tatctcgtcc agaagttatc gtaaaagaaa tcgacggtgt
    23341 taaatgtgaa ccatttgaac gtgtacaaat cgacactcca gaagaatacc aagggtctgt
    23401 tatccaaagc ctttctgaac gtaaaggtga aatgttggat atgatttcaa ctggtaatgg
    23461 tcaaactcgt ttggtcttcc ttgttccagc gcgtggtttg attggatact caactgagtt
    23521 cttgtcaatg actcgtggtt acggtatcat gaaccatacc ttcgaccagt acttgccatt
    23581 gattccaggg gaaattggtg gacgtcaccg tggtgccctt gtttctatcg atgctggtaa
    23641 ggctacaact tactcaatca tgtctatcga agaacgtggt acgatctttg tcaacccagg
    23701 tactgaggtt tatgaaggaa tgatcatcgg cgaaaactct cgtgaaaatg acttgacagt
    23761 taacatcacg aaggcaaaac aaatgaccaa cgttcgttca gctactaagg accaaacagc
    23821 tgttatcaag acgcctcgta tcttgacact tgaagagtct cttgagttct tgaacgacga
    23881 tgagtacatg gaagtaacgc ctgagtctat ccgtttgcgt aaacaaatcc ttaacaaagc
    23941 agagcgtgag aaagctaaca agaagaaaaa atcagctgaa taagagctag aaagagagaa
    24001 agatggtcta tttagtccta ggaattttac tgctcctact ctatgtattt gcgacaccag
    24061 aaagcattaa agggacagtc aatatcgtcg ctatggtatg tattttagtg gcactcttga
    24121 ttttattggt tctatctttt ctgaaaattt ttcaattacc aacagaaata ttcctagcaa
    24181 tagccatgtt gatcctagct tactttagtg tgagagacat cacactcatg ccagtcaaaa
    24241 aaagtaaaag aagataaaaa agagagtttt ggctctcttt tttgctagga attttacaag
    24301 attgcaattt atttttgagt tatcaccatc tcttttgttt ggataatatg aatgggaaaa
    24361 acttgaataa aattctttaa tggaatctat tttatatttg cttagtactg gttgcatatt
    24421 atttcgaaat aaaactacta tataatatta ttcatagaga taatatagta aaatatctaa
    24481 aaaattcgat tttttccttg acaacaaata ataaaaatgt tattcttatc acataagaaa
    24541 gcggtttcaa caaaagagag aggaggattt attttgttgc attgttgctc agggtgtgct
    24601 ttttttgaaa gaaaaaataa aatgaaaacg aaaaaacata gattacttgc tctagctctt
    24661 atttcaagtt ttacattatt gggagctgca tcagctgctg tacaatatcc agatggagga
    24721 gtatggacat atggagaagg ttcaggaggt ggttgggctt tttcaaatta ctatcatggt
    24781 aaaaaatatc attattcatc catcgtgagc agatggaatg gtcattctga taaaggagaa
    24841 gctcctgctg gaaaaacctc ctatgcatgg atttggacta aatggggaga acaagtagca
    24901 ttttactgtg attatgacta atcgttcatt gatttaaatc gttccccttg taagaaatta
    24961 cagggggaat tttgtttaca aggagtctac tatgaagaaa ctattcatat tattatcaac
    25021 tttttttctc agcttcttcc ttgcttggat tattgtctta cgtgcgccac aatatttata
    25081 tgcaagctat gattccgttt ctttacttcg tgtcaaaaaa gatactcagg aaccgacgcg
    25141 tgaggtattt gaacaggaat tggagaattt tgcaaattca gaacagagtt taatagctag
    25201 aagaattgta gagccgagta aggatgggac gactcacttt atttatgcaa cttatggtca
    25261 gggaacttta ccaaaagaat tccaagaagc tagccaagaa agtcgtgaac gtagtgatcc
    25321 gctaaatagt tatctccttt tgtcaggttc cttgacgaaa gaaaagcttg ccgataaatt
    25381 aggagatttg ggttataaag caagtgctga ccgaaagata ccgccctatt ttcttgcttt
    25441 tcgaatatta ctaaatcccc ttattttaat tagtttagca atatttggct tatctttctt
    25501 tgctttagtg attatcactc ggattaagga aatgagagca gcaggtataa aactcttttc
    25561 tggtcagact ctcttatcca tcatggggca ttctttatct actgatatca aatggctcct
    25621 tctatcagcc ctcctttcct tcctaggtgg gggagtcgtt ctttttagtc aaggtttgtt
    25681 ttatcctatc ttgttagcca cctatggttt tgggattagt ttctatctgt tgtttttatt
    25741 ggcgatttca attttactaa tgctccttta tctaatgagt ttgaattaca aagcattagt
    25801 tcccgttatt aaggggagat taccccttaa acgcctgatg attttaaccc tattgtgtca
    25861 gttggttgct gtctttacag taggatacgc tgttaagaca ggtttgacgt cttaccaacg
    25921 attgaaagaa cttgaaattt caaaacaagc atggcaggat agagcagact attatcaaat
    25981 ttcttttggc ttaggtgata gaggaaaaga tatagaaaat cagagcaagt ggtatgcctt
    26041 tgccaaggaa gcaatcgaag aagaacaagc tctttatgta aaggataatc tgctccattt
    26101 tgccaatcca caaggaaaaa atgaacaggg agagacactg gatacctata gtccagatgc
    26161 taatacgctc tatgttagtc ccagttattt ggacaaggaa aaggtcgtgg tagatgctga
    26221 gaccaaacag aagttagccc atctccaaaa aggtgagttt atcctcttgc tcccagaaca
    26281 tttgcgctct cgagaagcag aacttaagaa agtttttgaa gaaagattga gttattatgg
    26341 aaaatctggt gaggaggcaa gtgctccttt ggattatgag atgaaagcgc acgttagtta
    26401 tctttcaatg ggagaaaagc ggtttgttta taataacggt gagaatcccg tatccactca
    26461 gtatttgact gatccgattt tagtggtatt cacgccgact tctacaggtg atagttttat
    26521 atccttatct agttggtcta tcaatgctgg aaaacaactc tttatcaaag gatatgagag
    26581 tgggctagaa ctcttgaaga aagctggaat ttatgagcaa gtatcctatc ttaaagaagg
    26641 aagaagtgtt tatctaactc gttataatga agttcaaact gaaacagcaa ctttaatctt
    26701 aggagctatt gtggggatag ctagttcctt gttactattt tattctgtca atattctata
    26761 tttcgagcaa ttccgccgag atatcttgat taaacgaatt tcaggtttac gattttttga
    26821 aacacatgct cagtatatgg ttagccaatt tgccagtttt gtatttggtg ctagtctctt
    26881 tattttaagc agtcgagact tggtgattgg cttgctcact ttattggtct ttctagctag
    26941 tgcagttttg acgctttacc gtcaagcgca gaaagaatct cgtgtttcta tgacaattat
    27001 gaaaggaaaa taggatgatt gaactaaaga atatatctaa aaaatttgga agccgtcagc
    27061 tattttcaga tacgaatctt cattttgaag gtgggaaaat ttatgcctta atcggtacaa
    27121 gtggctgtgg taagacaaca ctcttgaata tgattggacg attggagcca tatgacaaag
    27181 ggcaaatcat ctatgatggc acttctctta aggacatcaa gccttctgtt ttctttagag
    27241 attacttggg atacttattt caagattttg gcttaattga aagccaaacc gtcaaagaga
    27301 atctcaatct gggtttagtt ggtaaaaagt tgaaggaaaa agagaaaatc tctttgatga
    27361 aacaagctct aaaccgtgta aacctctctt atttggattt gaagcaacct atatttgagt
    27421 tatcaggagg agaagcacaa cgtgttgcac tagcgaagat aattttaaag gatccgcctt
    27481 tgattcttgc agatgaacca accgcttcct tagaccccaa aaactctgag gaattacttt
    27541 ccatcctaga atctttaaaa aatccgaatc ggaccattat tattgcgacc cacaatcctc
    27601 tgatttggga gcaagtggat caggtcattc gagttaccga tttatcacat agatgatatg
    27661 gtaagattca gttagaagaa agagtcacaa acacactttg tggctttttt atttccataa
    27721 aaatggtaaa atagtaggag tagaaatgga gttcgagaca tgaaagtaat agatcaattt
    27781 aaaaataaga aagttcttgt tttaggtttg gccaagtctg gtgaatctgc ggctcgtttg
    27841 ttggacaagt taggtgccat tgtgacagta aatgatggga aaccattcga ggacaatcca
    27901 gctgcccaat gtttgctgga agaagggatc aaggtcatta caggtggcca tcctttggaa
    27961 ctcttggatg aagagtttgc ccttatggtg aaaaatccag gtatccccta caacaatccc
    28021 atgattgaaa aggctttggc caagggaatt ccagtcttga ctgaggtgga attggcttat
    28081 ttgatttcag aagcaccgat tattggtatc acaggatcga acggtaagac aaccacaacg
    28141 actatgattg gggaagtttt gactgctgct gggcaacatg gtcttttatc aggaaatatc
    28201 ggctatcctg ctagtcaggt tgctcaaata gcgacagaca agaacacgct tgttatggaa
    28261 ctttcttctt tccaactcat gggtgttcaa gaattccatc ctgagattgc ggttattact
    28321 aaccttatgc caactcatat cgattatcat ggattatttg aggaatatgt agcagccaag
    28381 tggaatatcc agaacaagat ggcagcagct gatttccttg tcttgaactt taatcaagac
    28441 ttggcaaaag acttggcttc caagacagaa gccactgttg taccattttc aacacttgaa
    28501 aaggttgatg gagcttatct ggaagatggt caactctact tccgtggtga agtagtcatg
    28561 gcagcgaatg aaatcggtgt tccaggtagc cacaatgtgg aaaatgccct tgcgactatt
    28621 gctgtagcca agcttcgtgg tgtggacaat caaaccatca aggaaactct ttcagccttc
    28681 ggtggtgtca aacatcgtct ccagtttgtg gatgacatca agggtgttaa attctataac
    28741 gacagtaaat caactaatat cttggctact caaaaagcct tgtcaggatt tgacaacagc
    28801 aaggtcgtct tgattgcagg tggtttggac cgtggcaatg agtttgacga attggtgcca
    28861 gacattactg gactcaagaa gatggtcatc ctgggtcaat ctgcagaacg tgtcaaacgg
    28921 gcagcagaca aggctggtgt cgcttatgtg gaggcgacag atattgcaga tgcgacccgc
    28981 aaggcctatg agcttgcgac tcaaggagat gtggttcttc ttagtcctgc caatgccagc
    29041 tgggatatgt atgctaactt tgaagtacgt ggcgacctct ttatcgacac agtagcggag
    29101 ttaaaagaat aatatgaaaa aaattgtctt tacaggtggg gggacggttg gacacgttac
    29161 cctcaatctt ttgttaatgc ccaagttcat cgaagatggt tgggaagtcc actatatcgg
    29221 ggacaagcgt ggtattgaac accaagaaat ccttaagtca ggtttggatg tcaccttcca
    29281 ttctattgcg actggaaaat tgcgtcgcta tttctcttgg caaaatatgc tggacgtctt
    29341 caaagttggc tggggaatcg tccaatcgct ctttatcatg ttgcgacttc gtccacagac
    29401 ccttttttca aaggggggct ttgtctcagt accgcctgtt atcgctgcgc gtgtgtcagg
    29461 agtgcctgtc tttattcacg aatctgacct gtctatgggc ttggccaata aaatcgccta
    29521 taagtttgcg actaagatgt attcaacctt tgagcaagct tcgagtttgt ctaaggttga
    29581 gcatgtggga gcagtgacca aggtttcaga tcaaaaaaat ccagaaccag atgaattggt
    29641 ggatattcaa agccacttta atcataaatt gccgactgta ttgtttgttg gcggttctgc
    29701 aggtgctcgt gtctttaacc aattggtgac agaccataag aaagaactaa cagagcgcta
    29761 caatattatc aatctaactg gagattctag cctgaatgag ttgagccaaa atctttttcg
    29821 tgttgactat gtgaccgatc tctatcaacc cttgatggaa ttggctgata ttgttgtgac
    29881 acgtggtggt gccaatacga tttttgagct cttggcgata gcaaaattgc atgtcattgt
    29941 gccacttggt cgtgaagcta gtcgtggtga ccagattgaa aatgcagctt actttgttaa
    30001 gaaaggctat gcagaagacc ttcaagaaag cgatttgacc ttggatagtt tggaagagaa
    30061 gctttctcac ttactaagtc acaaggaaga ttaccaagct aagatgaaag cttctaagga
    30121 attgaaatct ctagcagatt tttatcaatt gttgaaaaaa gatttatcat aaggaaagta
    30181 aatgtcaaaa gataagaaaa atgaggacaa agaaatcctc gaagaattga aagagttatc
    30241 agaatggcag aaacgaaacc aagaatatct aaaaaagaag gctgaagaag aagcggctct
    30301 agctgaggag aaggaaaagg aaagacaagc tcggatggga gaagaatctg agaagtcaga
    30361 ggacaaacag gaccaggaga gtgaaacaga ccaggaagat tcagaatcag ctaaggaaaa
    30421 gtctgaagaa aaagtagcat cctcagaggc tgacaaagag aaagaagaga aagaagaatc
    30481 agagtctaaa gagaaggagg aacaggataa aaagcttgct aaaaaggcta taaaggaaaa
    30541 accagccaaa gcaaagattc ctggtatcca tatcttgcga gccttcacga ttttatttcc
    30601 aagtctgctt ttattgattg tctctgccta cttgctcagt ccttatgcga ccatgaaaga
    30661 tattcgtgtt gagggaacgg tgcaaactac agctgatgat attcgacagg cttcaggcat
    30721 tcaggattcg gattatacga ttaaccttct gctagacaag gcaaaatatg aaaagcagat
    30781 taagtctaac tattgggttg aatcagctca acttgtctat caatttccaa ctaagttcac
    30841 tattaaggtc aaggaatatg atattgtggc ctactatatt tctggtgaaa atcattatcc
    30901 tattctttcc agtggtcagc ttgagactag ttctgtgagc ctgaacagtt taccagaaac
    30961 ttatttatca gttctcttta atgatagtga acaaatcaag gcttttgtct cagaacttgc
    31021 tcaaattagc ccagaactca aggcggctat ccaaaaggtg gaattagccc caagcaaggt
    31081 gacatccgat ttaattcgat tgaccatgaa tgattcggac gaagtcttgg ttcctctatc
    31141 tgaaatgagt aagaaactgc cttattatag taagattaaa ccacaattgt cagaaccgag
    31201 tgtgattgac atggaagctg gaatttacag ttacactgtg gcggataaat taattatgga
    31261 agctgaggaa aaagccaaac aagaggctaa ggaagccgag aaaaaacagg aagaagaaca
    31321 gaaacgttta gaagaagaac agaaaaaaca agaggaagag agcaatcgaa atcaaacgac
    31381 ccagcgctca tcgcgtcgct aggtttacct tttctcttat agttctttag tgaccatgtt
    31441 tttacttgac aagtgctagt agaaataata gaatagtaaa aaacctttaa agcagtccag
    31501 agaggcagct aaggttagac ggtgaaaggg tggagactac ccatttttcg tggaaccttg
    31561 ctgttggcag gttccttttt tcgtggcttc tgttggccag actctctcac tagtaaaggt
    31621 aaaaggagaa acctatgcga gaacatcgtc caatcattgc tcttgatttt cctagttttg
    31681 aggcggtcaa ggaattttta gctcttttcc cagcagaaga aagcctttat ctcaaggtag
    31741 ggatggagct ttattacgca gcggggcctg agattgtgtc ctacttaaaa ggtttgggtc
    31801 atagtgtctt tttggatctc aaacttcatg acattcctaa tacagtcaag tcagccatga
    31861 aggtcttgtc tcagcttggt gtggatatga ccaatgtcca tgcggctggt ggtgtagaga
    31921 tgatgaaggc ggcgcgtgaa ggtcttggga gtcaagccaa attgatcgct gtaacgcagc
    31981 tcacatcaac gtcagaagct cagatgcagg agtttcaaaa tatccaaacc agtctgcaag
    32041 agtctgtgat tcactatgcc aagaagacag ctgaagctgg cttggatggt gttgtttgct
    32101 cggctcagga agtacaagtc atcaagcagg ctaccaatcc agattttatc tgtctgacac
    32161 cagggattcg tccagctggt gttgcagttg gagatcaaaa acgagtcatg acacctgctg
    32221 atgcctatca aatcggcagt gactatatcg tagtgggacg tcccattacc caagctgagg
    32281 atcctgttgc agcttatcat gccatcaagg atgaatggac acaggactgg aattaaagaa
    32341 ctagattaga aaaataaaag gagaatacca tgacacttgc taaagatatc gctagccacc
    32401 tcttgaaaat ccaagccgtt tacctcaaac cagaggaacc cttcacttgg gcatctggta
    32461 tcaagtcacc gatttacact gataatcgtg tgacactagc ctatccagaa actcgtaccc
    32521 taattgaaaa tggttttgtg gaagctatca aagaagcctt tcctgaagta gaagtgattg
    32581 caggaactgc aacagcaggg attccacacg gagccattat tgctgataag atggacttgc
    32641 cttttgccta cattcgtagc aaaccaaaag accacggagc tggtaatcaa atcgaaggtc
    32701 gcgtagctca aggtcaaaaa atggtagtgg ttgaagacct tatttcaacg ggtggttcag
    32761 ttcttgaagc tgtagcagca gccaagcgag aaggagcaga tgtacttgga gttgtagcga
    32821 ttttcagcta ccaattgcca aaagcagata agaactttgc agatgctggt gttaaacttg
    32881 tgacgctttc aaactatagc gagcttatcc atctagccca agaagaaggt tacatcacgc
    32941 cagagggcct tgatcttcta aaacgcttta aagaagacca agaaaattgg caagaaggtt
    33001 aggtcagtaa gataaagaga gacgaggcta ccgagtctct tttaccattt tatttaaaat
    33061 atgacaatat tttaaataaa ataattgaca acgctttctt ttgttgatat aatgaaaatg
    33121 taatatgtat caaattgatc aatcaactat cttgtttatc acttcttaag aggacgatgt
    33181 catgaaaaga agaaaaatat attccttttt tgcgtagtta caattgcatc tagtttgttt
    33241 ctccctacag ttttagctag acagattgga aattatgatt taacgttgcc gcgttggggt
    33301 tcggatacaa ctagtgagct tgagaaagaa aacgcctctg ctggaattaa taatagtgac
    33361 agcactggtg gcggtaaaag gttaaatacc tctattcgta gcgcctatag tgggtcagat
    33421 attaccccgg tatattcatt ggggtctggc tctaggattg tcatgtacta taatggaggt
    33481 ggtgacaatt atattggttc tggtactaga ttagctatgg cgccacaatt tggaaatcat
    33541 gtaagaattc atacttcagg ttcttggagt ccagattctt attaacttac ttgtcagagt
    33601 aagccttaaa gatggttgat tgtgggtgta gcatgaaaaa agaatgctac accctatttt
    33661 tattataagg aggagtaagg atggaatttt tcatttgtaa tcttgtacga gtcgttcaat
    33721 cacctcggtt ttatatgtct ttatttttga cccttctttg catgagttta ggaaattttc
    33781 ttgctttcaa tggtatttat aaaattgaag gtttatcgat tttttttgcc gcttcttcta
    33841 ttcgaggatt ttcaccgatt agcctagtag ctgcacttat ctgtacactg ccctattcta
    33901 gtcagataat agaggatgct gagagtcatt ttctaacagc acaattgtgc cgaatttcta
    33961 aaaagaggta tctagctatt gtaggtagta ctgcaattat ttcttctttt ctagtctttt
    34021 ttctccccta tttattatta ttaggaatta atcttttagt gactccttat caggaaattt
    34081 atattggaga ttatagtggt gccttaaaag aattatttga ttctaatcag tttctctata
    34141 gtcttgtgac gactctctgg tatggagttt ggggcgctgt gttctctatt tttggactag
    34201 ctagtgcttt gctagtgaag aaaaaattag gagctatttt catcccagtt gcctatatga
    34261 tggttggtgg tattttatgg gctattttag ggctatctta cttagaacct gtgacaacgc
    34321 tagctttggg atatcagaaa gatatcagtc tttccttagt tagtgggcat cttgctttta
    34381 ttttatttgt tagttgtttg gttgtttatg gtacattttt tctacattca gaggactatg
    34441 tataatgaaa caatttgttc aattttataa aaaagatttc ttagcagtat tggtttattt
    34501 tatattactg ctatcctgtg ttttatctag tacagtatat ttattgcgct gtcgccaata
    34561 ttcaatccat ccaaatgtat tagaatggat cttagtttta cttcaagata tgacgactgg
    34621 agtatattgc tttccgttca catatatatt gttctttttt tatttgatga ataactattt
    34681 taataggttg gagtgtcgca ttcgtctgaa atcaattaag cactttacca gttttagttt
    34741 caaattagca gctcttagta cggggatttg gacggcgact ttatttttat tgatttttct
    34801 aattgcattt agtaatggtt ttagcttctc tttggagata aaggaggttg attttttaag
    34861 agaattttat ggtataagta ttgcaaacaa tgctagtttc tttataggat tttttttctc
    34921 ttatatagca tactatttct ttttatcctt acttactatt agcagttttt cttggtttaa
    34981 aaaatcaaac atgagcttag tatttctgtt tactttttta tttgtagaat ccttattctg
    35041 gatttatcag ttggacaatg ggataattgg attattgcca atttttcagt atatggtaaa
    35101 ttccaatccg tatgcattga tttattggct tacattacta tctatcataa ttccattgac
    35161 tgtattttct gttcatagaa actggaggag agtgtaaaag ttggaaatgg gaaagttaag
    35221 tagtcacatg tggaggttga atcagataat ctataccaag tacttttggg gttatgttct
    35281 tttttggata ttgatttgtt taggattatg gtattggtta gaaggaaatg atagacttgt
    35341 tatagaaatt ttaaaagggc ctaatctgag tcaaaactct tttttagtct tatctatatg
    35401 gttgcttcat tggtttatta ttcatacatt ttttctagca gttgtatatc gtagaagagc
    35461 atccgatttc tttatggaag tgattcgatt ttcttctatt aagctctgga ttaggtatca
    35521 gatttggacc tgttttcttt atggactcat tttaatcatg gtaaaagttc tagtgattca
    35581 atttatgtta cagttaccaa actgggatat aggagttttg tttatagttg attctttgaa
    35641 tgcttgtgtg ttagtcttgt tttgctttat gttatacgca ctaggagcga atgtacaaat
    35701 gaactttgct tgcgttagtt tctttttact catgattgtg tttggtggtc tatttgtagg
    35761 aaatcgaact aattatctat tttatatttt gaatcgaggg aatggagata taggacgaga
    35821 tttatttctt cagttgctat ttttagtctt tctttttaaa agtattttct atttcactcg
    35881 tcaaaagagg aggtttatag aatgaatgaa ataatcatat taaaaaatat tgagttgaaa
    35941 ttaaaaaaaa catgtgtttt tcaaaacctt aattttagtt gtaaacaggg ggaaattata
    36001 ggaattactg gtgcgaatgg ctcagggaaa agtgtattgt ttaaattaat agctggttta
    36061 tatagtccgt cttatggaga agtgttaatc aatggggaaa atattgttcc tgagagaaaa
    36121 attccagcta atttgggagc tttgattgaa gaacctggtt ttataaatta ttatagtggc
    36181 tttaagaatt tacaatattt ggcaagcata cgaggagtag ttggtaatca ggaaatcaat
    36241 gatacactga aaatagttgg tctatatgag caaaaagacc agaaagttaa aacttattcg
    36301 ctaggtatga ggaaaaagct agggattgct caagcaatta tggagaatcc ctctattctt
    36361 ttactagatg aacctatgaa tgccttggat aaatcaagtg tagaaaatat gagaacattg
    36421 tttagaaagc tctctagtga aaaagggaca acaattttga ttgctagtca cagtgaagag
    36481 gatattcgta tcttatgtga taaagtatat gcaatagaag ataaagtatg tacactgtgt
    36541 tcagattgaa catcttagat agactcagga tgttataggt aaaatcttaa aaagggattg
    36601 gagcttaaaa tccagtccct tttaagagtt aatggccacc ttcaacaacc aggtcatctg
    36661 ctttagcagc gtcaccgtag gttgggtgaa gtgttttttc ataggccttg tggaagaagt
    36721 tttccttgcc taatttttca atatctttat tgatgaagtc tagcaattct tggttgcctt
    36781 tttgaactgc tgccgcaatg gtatcgggat caccgaggga agtaattcct acttcaaatc
    36841 ctttattttc aagcgcccaa gctagaactt ccgtattgtc agttgaaaag gcatctccac
    36901 gtccgtcaag aagagcttgg taagagtcac tgtattggtc gtatttttgg agtttgattt
    36961 ctggatgatt cttttcaaaa taagtctcag cagtcgttcc ttttgtgaca attaaggttt
    37021 taccttcaag ttgtttgacg tctgtaatga gaccagtctt aggtgatacg acacccagag
    37081 aaactttcat atatggaagg gcaaaatcaa cttgtttctt acgttcgtca gttactgtaa
    37141 agttagcaag agtaatatct accttgtttg aaatcaagta ttccgcacgg ttgtcagcat
    37201 cgactgaaat gtatttaacc ttgacaccaa ggtcttgagc tagttggttc cctagttcaa
    37261 tatcgtagcg tagccttggt aagaaccatc attgtcaacg tagccaaacg gttttttatc
    37321 tccaaacacg gcgattcgca gttcaccgct ttttttgatt tcatcgatag tgcgagcttt
    37381 ggcagttgtt tttccagagg atgaaccagc gtttccacct gagctacaag cagtgataaa
    37441 gataagggca aaggcaagtg ctaaaacagt taagagtggt ttgaatagtt tcataagaat
    37501 ctcctttata gatatgagcc gaattggcta aagtcaaaga cgtttaaaaa ttcctgggct
    37561 cgtttggttt gcggattggt aaagaaggct tgagctgttc cttcttcagc gattttccct
    37621 tggtcgagga agataatctg gtcagcaatg gcttgggcaa actgcatttc gtgggttact
    37681 aaaatcatgg tacggccttc ttgggccaaa tcattgataa gttccagcac ctcacgcacc
    37741 atttctggat ccagcgaagc agtcacctcg tcaaaaagga tgatttctgg atgcattagg
    37801 agggcacgga caattgcaac acgttgcttc tgtccaccag ataattgacg ggcaaagcta
    37861 tgttgtttat ccagcaaacc gacacgatct agtaattgca aagcttcttc cgttacttct
    37921 ttcttgtccc ttccttgagc tttgataggg cctaggatga ggttttgtaa gacatccaga
    37981 tggggaaaga gttcataact ttgaaagacc atgccaatct tttggcgaac taggtgaaaa
    38041 tcttttttat tttcaacgat agactgacca tccagaagaa tatctccacc ttgaatactt
    38101 tctaagccgt tgaggcaacg aaggagggta cttttcccac aaccagaggg ccctaggatg
    38161 acaacaactt cccttttttg atttctagag aaagtccttg gaggatggga ttgtctccga
    38221 aggatttttt tagttccttg atttctaaga tagtttcaga catttagttt ctccaatgtt
    38281 tttctaagtg agtggatagt ttggaaatag ggtagcaaac tgcgaaatat aagactagaa
    38341 tggttccata aatccaaaat gaagcagttg ggatggtcag gcgattgcta tcgatgattt
    38401 gttgtccaac tttggtcact tccacaaccc caatcaaaac aactaat
//
LOCUS       DAVHSY010000017        37216 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.017, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000017 DAVHSY010000000
VERSION     DAVHSY010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37216
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.017"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            144..1169
                     /gene="trpS"
                     /locus_tag="VVR43_001071"
     CDS             144..1169
                     /gene="trpS"
                     /locus_tag="VVR43_001071"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU6149437.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            1321..2799
                     /gene="guaB"
                     /locus_tag="VVR43_001072"
     CDS             1321..2799
                     /gene="guaB"
                     /locus_tag="VVR43_001072"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU6149438.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(2850..3947)
                     /gene="recF"
                     /locus_tag="VVR43_001073"
     CDS             complement(2850..3947)
                     /gene="recF"
                     /locus_tag="VVR43_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU6149439.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(3950..4318)
                     /gene="yaaA"
                     /locus_tag="VVR43_001074"
     CDS             complement(3950..4318)
                     /gene="yaaA"
                     /locus_tag="VVR43_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU6149440.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            4477..5727
                     /locus_tag="VVR43_001075"
     CDS             4477..5727
                     /locus_tag="VVR43_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU6149441.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLALDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILDETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERTYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            5724..7007
                     /locus_tag="VVR43_001076"
     CDS             5724..7007
                     /locus_tag="VVR43_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU6149442.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLYLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            7049..7870
                     /locus_tag="VVR43_001077"
     CDS             7049..7870
                     /locus_tag="VVR43_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6149443.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            7881..8426
                     /gene="pgsA"
                     /locus_tag="VVR43_001078"
     CDS             7881..8426
                     /gene="pgsA"
                     /locus_tag="VVR43_001078"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU6149444.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIVLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            8423..9250
                     /locus_tag="VVR43_001079"
     CDS             8423..9250
                     /locus_tag="VVR43_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU6149445.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            9235..10074
                     /locus_tag="VVR43_001080"
     CDS             9235..10074
                     /locus_tag="VVR43_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU6149446.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            10067..10861
                     /locus_tag="VVR43_001081"
     CDS             10067..10861
                     /locus_tag="VVR43_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU6149447.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            10920..11738
                     /gene="mreC"
                     /locus_tag="VVR43_001082"
     CDS             10920..11738
                     /gene="mreC"
                     /locus_tag="VVR43_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU6149448.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            11738..12232
                     /gene="mreD"
                     /locus_tag="VVR43_001083"
     CDS             11738..12232
                     /gene="mreD"
                     /locus_tag="VVR43_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU6149449.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            12326..13504
                     /locus_tag="VVR43_001084"
     CDS             12326..13504
                     /locus_tag="VVR43_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU6149450.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            13728..14507
                     /gene="rpsB"
                     /locus_tag="VVR43_001085"
     CDS             13728..14507
                     /gene="rpsB"
                     /locus_tag="VVR43_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU6149451.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            14586..15626
                     /locus_tag="VVR43_001086"
     CDS             14586..15626
                     /locus_tag="VVR43_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU6149452.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            15872..16195
                     /gene="tnpB"
                     /locus_tag="VVR43_001087"
     CDS             15872..16195
                     /gene="tnpB"
                     /locus_tag="VVR43_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU6149453.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
     gene            complement(16336..16644)
                     /locus_tag="VVR43_001088"
                     /pseudo
     CDS             complement(16336..16644)
                     /locus_tag="VVR43_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            16635..17033
                     /locus_tag="VVR43_001089"
     CDS             16635..17033
                     /locus_tag="VVR43_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6149454.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(17230..18150)
                     /gene="cysK"
                     /locus_tag="VVR43_001090"
     CDS             complement(17230..18150)
                     /gene="cysK"
                     /locus_tag="VVR43_001090"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU6149455.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(18435..19070)
                     /locus_tag="VVR43_001091"
     CDS             complement(18435..19070)
                     /locus_tag="VVR43_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU6149456.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYTSSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            19126..20424
                     /locus_tag="VVR43_001092"
     CDS             19126..20424
                     /locus_tag="VVR43_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6149457.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            20421..21083
                     /locus_tag="VVR43_001093"
     CDS             20421..21083
                     /locus_tag="VVR43_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU6149458.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQFWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            21163..21711
                     /gene="raiA"
                     /locus_tag="VVR43_001094"
     CDS             21163..21711
                     /gene="raiA"
                     /locus_tag="VVR43_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU6149459.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            21847..23820
                     /locus_tag="VVR43_001095"
     CDS             21847..23820
                     /locus_tag="VVR43_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU6149460.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            23817..24269
                     /gene="rplI"
                     /locus_tag="VVR43_001096"
     CDS             23817..24269
                     /gene="rplI"
                     /locus_tag="VVR43_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU6149461.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            24313..25665
                     /gene="dnaB"
                     /locus_tag="VVR43_001097"
     CDS             24313..25665
                     /gene="dnaB"
                     /locus_tag="VVR43_001097"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU6149462.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            25667..25933
                     /locus_tag="VVR43_001098"
     CDS             25667..25933
                     /locus_tag="VVR43_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149463.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            26022..27368
                     /gene="cbpD"
                     /locus_tag="VVR43_001099"
     CDS             26022..27368
                     /gene="cbpD"
                     /locus_tag="VVR43_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU6149464.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      27451..27553
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            27624..27914
                     /locus_tag="VVR43_001100"
     CDS             27624..27914
                     /locus_tag="VVR43_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU6149465.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            27877..28635
                     /locus_tag="VVR43_001101"
     CDS             27877..28635
                     /locus_tag="VVR43_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6149466.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            28673..29680
                     /locus_tag="VVR43_001102"
     CDS             28673..29680
                     /locus_tag="VVR43_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6149467.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            29680..30408
                     /locus_tag="VVR43_001103"
     CDS             29680..30408
                     /locus_tag="VVR43_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149468.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            30527..30985
                     /locus_tag="VVR43_001104"
     CDS             30527..30985
                     /locus_tag="VVR43_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU6149469.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLVSVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            30987..33419
                     /locus_tag="VVR43_001105"
     CDS             30987..33419
                     /locus_tag="VVR43_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU6149470.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            34061..34714
                     /gene="rr06"
                     /locus_tag="VVR43_001106"
     CDS             34061..34714
                     /gene="rr06"
                     /locus_tag="VVR43_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU6149471.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            34711..36042
                     /gene="hk06"
                     /locus_tag="VVR43_001107"
     CDS             34711..36042
                     /gene="hk06"
                     /locus_tag="VVR43_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU6149472.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVSNILESYQMDYSFLPYEHGMEFKISL"
     gene            36137..36664
                     /locus_tag="VVR43_001108"
     CDS             36137..36664
                     /locus_tag="VVR43_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU6149473.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            36743..>37216
                     /locus_tag="VVR43_001109"
     CDS             36743..>37216
                     /locus_tag="VVR43_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HEU6149474.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEEVGGRN
                     TPTVTSSGQDISKKYADEVESHLKKILSEIQTQLDRKRHTKTVALINELQNIKKTYLY
                     NLNVLKEKSELPSKIKAKLEVAFDQFKKDTLKPGEKVAEAEKKVAEAKKKAEDQKE"
BASE COUNT        11579 a         6026 c         8187 g        11424 t
ORIGIN      
        1 ttatttgtca attttgtgta aattatattt acagtatcct ttacacaaat ctgtaaaaag
       61 caaggctgat ttattttgat aaattacggt tatttcatta aaaaaatgct ataattgaaa
      121 ggactatatc gaaggagaac aaaatgacta aacccattat tttaacagga gaccgtccaa
      181 caggaaaatt gcatattgga cattatgttg gaagtctcaa aaatcgagta ttattacagg
      241 aagaggataa gtatgatatg tttgtgttct tggctgacca acaagctttg acagatcatg
      301 ccaaagatcc tcaaaccatt gtagagtcta tcggaaatgt ggctttggat tatcttgcag
      361 ttggattgga tccaaataag tcaactattt ttattcaaag ccagattcca gagttggctg
      421 agttgtctat gtattatatg aatctagttt cgttagcacg tttggagcga aatccaacag
      481 tcaagacaga gatttctcag aaaggatttg gagaaagcat tccgacagga ttcttggtct
      541 atccaatcgc tcaagcagct gatatcacag ctttcaaggc taattatgtt cctgttggga
      601 cagatcagaa accaatgatt gagcaaactc gtgaaattgt tcgttctttt aacaatgcat
      661 ataactgtga tgtcttggta gagccggaag gtatttatcc agaaaatgag agagcagggc
      721 gtttgcctgg tttagatgga aatgctaaaa tgtctaaatc actaaataat ggtatttatt
      781 tagctgatga tgcggatact ttgcgtaaaa aagtaatgag tatgtataca gatccagatc
      841 atatccgcgt tgaggatcca ggtaagattg agggaaatat ggttttccat tatctagatg
      901 tttttggtcg tccagaagat gctcaagaaa ttgctgatat gaaagaacgt tatcaacgag
      961 gtggtcttgg tgatgtgaag accaagcgtt atctacttga aatattagaa cgtgaactgg
     1021 gtcctattcg tgagcgccgt attgaatttg ctaaggatat gggagaagtt tataatatga
     1081 ttcaaaaagg tagtgaaaga gcgcgtgaag ttgcgggtca aaccctatct gaggtaaaag
     1141 gggcaatggg acttcattac tttaactaag tttattttac aagaaactat catttctatc
     1201 tcgaagaaaa gatagttttt tatttacccc tgtaacattt gacaaatttt tatagaatgg
     1261 tatgatagat acaatataaa aagagtcaag ctcaaaaaga aagaaaagag gaaacttcga
     1321 atgtctaatt gggacactaa atttttgaaa aaaggtttta cctttgatga tgtattgctt
     1381 attccagctg aaagtcatgt gttgcctaac gatgcagatt taacaactaa attggcagat
     1441 aatttgactt taaatatccc aattattacc gctgccatgg acacagttac agagagtcaa
     1501 atggccattg ctattgctcg tgcaggtggt ctcggagtta tccataaaaa catgtcaatt
     1561 gctcaacaag cagacgaggt tcgtaaggta aaacgttctg aaaatggagt tattattgat
     1621 ccgttcttct tgacgcctga acatacaatt gctgaagcag atgagcttat gggtcgttac
     1681 cgcatcagtg gtgttccagt tgttgaaaca cttgaaaatc gtaaattggt tggtattttg
     1741 acaaaccgag atcttcgttt tatttcagat tataatcaac caatttcaaa ccatatgact
     1801 agtgaaaatc ttgttactgc tcctgtgggt acggatcttg caacggctga gagtattctt
     1861 caagagcatc gtattgaaaa acttccgttg gtcgatgaag aaggcagtct ttctggtttg
     1921 atcactatca aagatattga aaaagttatt gagtttccaa atgcggctaa agatgaattt
     1981 ggtcgtcttc tagttgcagg tgcagtaggt gttacttcag atacatttga acgtgcagag
     2041 gctctttttg aggcaggagc ggatgcgatt gttattgata ctgcacatgg tcattctgca
     2101 ggtgtcttgc gtaaaattgc cgagattcgt gctcatttcc cagatcggac tttgattgct
     2161 ggaaatattg ctactgctga aggtgcacgt gccctttatg aagcgggtgt agacgttgtt
     2221 aaggttggta ttggaccagg ttctatctgt actactcgtg tgattgctgg tgttggtgtt
     2281 ccgcaagtaa cagctatcta cgatgctgca gctgttgcgc gcgaatatgg taaaacgatt
     2341 attgctgacg gtgggatcaa gtattctgga gatattgtaa aagcacttgc tgcaggtgga
     2401 aatgctgtta tgcttggatc tatgtttgct ggaactgatg aagctccagg cgaaactgaa
     2461 atcttccaag gacgtaaatt caagacttac cgtggtatgg gatcaattgc tgctatgaag
     2521 aaaggttcaa gcgaccgtta tttccaaggt tctgtcaatg aagcaaacaa gctcgttcca
     2581 gaaggaattg aaggtcgtgt tgcttataaa ggagcggcag ctgatattgt tttccaaatg
     2641 attggtggta ttcgctctgg tatgggttac tgtggtgcag ctaaccttaa agaactacac
     2701 gataatgctc aatttattga aatgtctggt gctggtttga aagaaagcca tcctcatgat
     2761 gtgcaaatta ctaatgaggc accaaattat tctatgtaaa aaacaatgaa aagaactcca
     2821 gtgaaaacag gagttctttt acaatgttgt caatttccat ttacagaagc tttaccatcc
     2881 tgaatagtga agatacttag attttctggc agattttgaa gatggtctaa gcttgttgtt
     2941 gtgataaagg tttggattga ttgagaaatc gtttctaata attttaactg tctagtgttg
     3001 tcaagttcac tcatcacatc gtcaagcagt aatataggag attctgtggt aatgctttcc
     3061 attaattcga tttctgctaa ttttatcgag aggacgagac tacgatgttg accttggctt
     3121 ccgaaactag catccatccc atttatataa aaagaaatgt catctcgatg aggaccgaca
     3181 ccagtattct ttttaaataa atctctggat ctactttttt ctaaagcaat tttgaaagat
     3241 tcggataagt tttgtttgtc agttatattg acagaagatt gataggatat tgacaactct
     3301 tcgatctgat tagagagttc aaaatgtttc ttacgcccaa atgattctag tttttttatg
     3361 aaatctaagc ggtgattcat tacacgacat ccataatcaa ctagctgatc atctaacaca
     3421 gaaaggaatg tttcatctat tttttgagct gattttaggt aagtgtttct ttgctttagg
     3481 atgtggttat aattggttaa gtcagataaa tagattggct taatttgccc aagttccata
     3541 tcaatgaatt ttcgtcgaat cgaaggtgct cctttaatta gttgtaaatc ttcaggagca
     3601 aataagacaa cattcatgtg tcctacataa tctgaaaggc gtgcctgttt taagtgatta
     3661 acttttgtta cacggccttt ttgtgttagt tcgatttcta ggggaatgga tccagttttt
     3721 ttctgaacga gacctgaaag atgaagttgt tcctcatcaa aatgaatgag atttttatct
     3781 gttcgagttc gatgactacg cgttaaggct aaaaaataga tagcctctaa catgtttgtt
     3841 tttccttgtg cattacgtcc caaaaagaca ttcaatttag gattaaagtc tattttcgtt
     3901 tctttgtaat tacgaaaagt cttgagagat agatgttgta gccacatgat tatctaccag
     3961 ggaatcgtgg agcttgttgg cttttaggtg atgaagcagg tttcgatttg tcttttttaa
     4021 ctcccttatt catctttttg acaagtttag cgatccgttc tttttcaact ttatcagctt
     4081 ggtattcatc ttgttcttca gaagtaggtt gtgtcaacaa gatgtcaatg ttcatgtcag
     4141 ggatgtcaac tttatcgcca atacgaagtt tttttccacg acgactctct aattccctat
     4201 taaagtaaac agaatgttca gagagaaatg atttaatagc tcctccgcta tgtgtaattc
     4261 caagttcttt gagtagtgct tggagggtaa taaattcttc aaataatttg tattccataa
     4321 ttcacctcaa tctttggtat tataccatat tttcctaaaa atagtgagag agacagcgag
     4381 aaatgtaagc gatttttatt tcaaaagtgt tacagggaac aagaaaattt caggttttcg
     4441 tgatataata gaagtctgta tataaggagg taaatcatgg agttagtgca tggaatttca
     4501 acacatttta tccaatcaaa aaagtttaaa acaaacaaaa ttaccgtgcg ttttaccgct
     4561 ccattagccc ttgatacgat tgcaggtcac atgttgagtg caagtatgct agagactgct
     4621 aatcagatgt accccacttc tcaagatttg aggagacact tggccagtct atacggtaca
     4681 gatatgtcaa ccaattgttt cagaagaggg caaagccaca ttatagaatt gacatttacc
     4741 tatgttcgtg atgagttttt aagtaggaaa aacgtgctaa cctctcagat tttggaactt
     4801 gtaaaagaaa ctcttttttc acccgtagta gttgataatg ggtttgatcc ggccttattt
     4861 gaaattgaga aaaaacaatt gctagcaagt ttagcagctg atatggatga ttctttttat
     4921 tttgcacata aagaattgga taaattgttt tttcatgatg aacgtcttca attggaatat
     4981 agtgatttac gaaatcgtat tttagatgaa actccacaaa gttcttattc ttgtttccaa
     5041 gaatttttag ccaatgatcg aatagatttc tttttcctag gtgattttaa tgaggttgaa
     5101 attcaaaatg tattagaatc atttggcttt aaaggtcgaa aaggagatgt gaaggttcag
     5161 tattgtcaac cttattctaa tatccttcag gaaggtatgg ttcggaaaaa tgtgggacaa
     5221 tctattttgg aattaggtta tcattaccgt tctaaatatg gtgatgagca acatttaccc
     5281 atgattgtaa tgaatggttt acttggtgga tttgctcact ctaagctctt tacaaatgtc
     5341 cgtgaaaatg ctggattagc ttataccatt tcaagtgagc ttgatttatt tagtggattc
     5401 ttgaggatgt atgctggtat caatcgagaa aatcgtaacc aggctcgtaa aatgatgaat
     5461 aatcaactgc ttgatttaaa aaaaggttat tttacagagt ttgagttaaa tcagaccaag
     5521 gaaatgattc gttggtcgtt gttactttct caagataatc aatcttcatt gattgaacgt
     5581 acttatcaaa atgccttatt tggaaaatct tcagcagact ttaaaagttg gattgcaaag
     5641 cttgaacaaa ttgacaaaga tgctatttgt agagtagcta ataatgtgaa actacaagcg
     5701 atttacttta tggaaggaat agaatgacaa aggttgtttt tgaagaaaaa tactatccag
     5761 ctgtaaaaga aaaggtttat cgaactcgtt tggccaacgg attgacagtt gctcttttgc
     5821 ctaaaaagga atttaaagag gtttacggga gtgtcactgt acagtttggt tcggtagata
     5881 cgtttgtcac agaagttgac ggagatgtaa aacaatatcc tggaggaatt gctcattttc
     5941 ttgaacataa attatttgag agagaagatt ctagtgattt gatgtcggct tttacgagtc
     6001 taggtgcaga tagtaatgcc tttacaagct ttacaaaaac aaactatctt ttttcagcaa
     6061 cggattattt tttagaaaat ttatatttac ttgatgaatt ggtaacatca gcacacttta
     6121 ctgaagcttc cattctgaca gagcaggata ttattcagca agaacgagaa atgtaccaag
     6181 atgatccaga ttcgtgttta ttcttttcaa ctttagcgaa tttgtatcct ggtacacctt
     6241 tagcaactga tatagttgga agtgaggagt ccatttccca aatcaatcta actaatttgc
     6301 aagaaaattt tacaaagttt tacaaacctg taaacatgtc tctgttttta gttggtaatt
     6361 ttgatgtgga gcgagtacag gactattttg aaagcaaaga actgaaagat tcagattttc
     6421 aggaagtagc aagagaaaag ttgtttttac agcctgtaaa gccaacagat agtatgagaa
     6481 tggaagtatc ttctcccaaa ctagcgattg gagttagagg taagcgagaa gtttctgaag
     6541 cggattgcta tcgacatcat attttattaa aattattgtt tgcaatgatg tttggttgga
     6601 cttcggatcg ttttcaaaaa tgttatgaat caggtaaaat tgatgcatcc ttatctctgg
     6661 aagttgaagt aacaagtcgc tttcattttg tcatgttgac aatggatacg aaagagccag
     6721 ttgctttgtc tcatcaattt aggaaggcta ttcgtaattt tacaaaggat ttagatatta
     6781 cagaggaaca tttagatatt atcaaaagag agatgtttgg cgaatttttc agtagcatga
     6841 actctcttga atttattgca acgcaatatg atgcttttga aaatggtgag acaatttttg
     6901 atttgccgaa aattttacag gaaattactt tagaggatgt ccttgatgct ggacatcatt
     6961 taatagatga tggtgacata gttgatttta caatattccc atcgtagtaa cctattataa
     7021 tagacactag aaagaaggga tgacaagtat gagaaaaaaa acaattggag aggttttacg
     7081 attagctaga atcaatcagg gattgagttt agatgaattg cagaaaaaga cagaaatcca
     7141 gttagatatg ttggaagcaa tggaagcaga cgatttcgat caacttccaa gtccttttta
     7201 cacgcgttct ttcttgaaaa aatatgcatg ggctgttgag ttagatgacc aaattgtttt
     7261 ggatgcttat gattctggga gtatgattac ttatgaggaa gtagatgttg atgaagatga
     7321 gttgacaggt cgtagacgtt caagtaagaa aaagaagaaa aaaacatcat ttttaccttt
     7381 attttatttt atcctttttg ctttatcgat tttaattttt gtgacttatt atgtttggaa
     7441 ctatattcaa actcaaccag aggagccttc tctttctaat tacagtgtgg ttcaatcaac
     7501 aagttcaact agctctgttc cccactcctc aagtagtagt tcttctagta tagaatcagc
     7561 tataagtgta tcaggcgaag gaaatcatgt agaaatcgct tataagacaa gtaaggaaac
     7621 agttaaattg caattggcag tttcagatgt tacaagttgg gtcagtgttt cagaaagcga
     7681 acttgagggc ggtgtaacct tatcgccaaa gaagaaaagt gcagaagcaa cagttgcaac
     7741 taaaagtcct gtaacaatta cgttaggtgt tgtaaaaggt gttgatttga cagtagataa
     7801 tcagactgtt gatttatcga aattaacagc tcagactgga caaattactg taacctttac
     7861 taaaaattaa ggaaaaacga atgaaaaaag aacaaattcc caatctctta acaataggtc
     7921 gaattctctt tatacctatt tttatcttta ttttaacgat aggaaattcg atagagagtc
     7981 atatagttgc agctattatc tttgctgttg ccagtattac cgactattta gatggatatt
     8041 tagctcgtaa atggaatgtg gtcagtaatt ttggtaaatt tgcagatcct atggcggata
     8101 agttactagt tatgtcggct tttattgtgt tgattgagtt aggtatggct ccggcttgga
     8161 ttgttgcagt gattatctgt cgtgagttag ctgtgacagg tttaaggctt ttattggttg
     8221 aaactggtgg aacaatttta gcagcagcaa tgcctggaaa aattaaaact tttagtcaga
     8281 tgtttgccat tattttcttg ctattacatt ggactttgct tggtcaagtt ctactttatg
     8341 tagccttatt tttcactatc tactctggct atgactattt caagggtagt gcctatgtat
     8401 ttaaagggac atttggttcg aaatgaaatc aataattgat gtaaaaaatc tttcttttcg
     8461 ctataaagaa aatcagaact actacgatgt gaaggatatt acgtttcacg tgaaacgtgg
     8521 agaatggctt tcgattgtag ggcataatgg tagtggtaaa tcaacgacgg ttcgattaat
     8581 tgatggctta ctggaagcag aatccggaga gattgtaatt gatggccaac gtttgactga
     8641 ggaaaatgtt tggaatatac gtcgtcaaat cggtatggtt tttcaaaatc cagacaatca
     8701 atttgttgga gcgactgttg aagatgatgt tgcttttggt ttggaaaatc agggactttc
     8761 tcgtcaagaa atgaaaaaga gagtagaaga agctctggct ttagttggca tgttggactt
     8821 taaaaagaga gagccagcgc gtctatcagg tggccaaaag caacgtgtgg ccattgcagg
     8881 tgttgtagcc ctaagaccag ctattttaat cttagatgaa gcaacgagta tgttggatcc
     8941 tgaggggcgt agagaactta ttgggacagt aaaaggaatt cgaaaagact atgatatgac
     9001 ggtcatttct attacccatg atttggaaga agtcgccatg agtgatcgcg tattggtcat
     9061 gaaaaaaggg gaaattgaat caactagtag tccaagggag cttttctctc gaaatgattt
     9121 agatcaaatt ggattagacg atccttttgc taatcaatta aaaaaatctt tgagccagaa
     9181 tggctatgat ttacctgaaa attatttgac agaaagtgag ctagaggata agctatggga
     9241 attgctctag aaaatgtgaa ttttacatat caagaaggta ctcccttagc ttcagcagct
     9301 ttgtcggatg tttctttgac gattgaagat ggctcttata cagctttaat tgggcacaca
     9361 ggtagtggta aatcaactat tttacaactc ttaaatggtt tattggtgcc aagtcaaggg
     9421 agtgtgaggg tttttgatac cttaatcacc tcgacttcta aaaataaaga tattcgtcaa
     9481 attagaaaac aggttggctt ggtatttcag tttgctgaaa atcagatttt tgaagaaacg
     9541 gttttgaagg acgttgcttt tggaccgcaa aattttggag tttctgaaga agatgctgtg
     9601 aagactgcgc gtgagaaact ggctctggtt ggaattgatg aatcactttt tgatcgtagt
     9661 ccgtttgagc tgtcaggggg acaaatgaga cgtgttgcca ttgcaggcat acttgccatg
     9721 gagccagcta tattagtctt agatgagcca acagctggtc tagatcctct agggagaaaa
     9781 gagttgatga ccctgttcaa aaaactccac cagtcaggga tgaccatcgt cttggtaacg
     9841 catttgatgg atgatgttgc tgaatatgca aatcaagtct atgtaatgga aaagggacgt
     9901 ttagtaaagg ggggcaaacc aagtgatgtc tttcaagacg ttgtttttat ggaagaagtt
     9961 cagttgggag tacctaaaat tacggccttt tgtaaacgat tggctgatag aggcgtgtca
    10021 tttaaacgat taccgattaa gatagaggag tttaaggagt cgctaaatgg atagtatgat
    10081 tttagggcgt tatatcccag gggattcgat tgttcaccga ttggatccac gtagcaaatt
    10141 gcttgctatg atgctactga ttttgattgt gttttgggct aataacccct tgacgaatct
    10201 gattcttttt atagcgacag ggatatttat tgccttgtca ggagtatctc tttcattttt
    10261 tattcagggc ttgaagtcta tgtttttctt gattgccttc acaactattt ttcaactatt
    10321 tttcatttct aatgggaatg ttttatttga gttttcgttt gtgagaatca cggattatgc
    10381 tttgcaacaa gctgggatta ttttttgtcg ctttgtattg attattttct tttcaacttt
    10441 gttaacctta acaaccatgc ctttaagttt ggcatcagct gtcgaagctt tattagcacc
    10501 tttaaagcgt gtgaaagttc cagttcatga aattggattg atgctgtcta tgagtttgcg
    10561 ttttgtccca accttgatgg atgatacgac gcggattatg aatgcacaga aagctcgtgg
    10621 agtggatttt ggagaaggaa gcatcgttca aaaagtaaag gcgatgattc ccattttgat
    10681 tcctcttttt gcgacaagtt taaaacgtgc agattccttg gctatcgcta tggaagcgcg
    10741 tggctatcag ggtggaaaag gcagaagtca ataccgacaa ttgaaatgga ctctaaagga
    10801 tacgctgacc attcttgtta ttctcgtact tggttgttgt ttatttttct taaaatctta
    10861 gtagctttca ggaattgata aaaagttact gtaacagttt ttgatataaa ggtagggata
    10921 tgaaccgttt taaaaaatca aaatatgtca ttattgtttt tgtcactgtt ctgcttgtgt
    10981 cagctctctt agcgacgact tattcaagta caattgtgac aaaattagga gatggaatct
    11041 cattggttga tagagttgta caaaaacctt ttcagtggtt tgattctgtc aaatcagatt
    11101 tggctcattt gacacgaaca tataatgaaa atgaaagttt gaagaaacag ctttaccaat
    11161 tagaagttaa atcaaatgag gtggaaagtt taaagacaga aaatgaacaa ctgcgccaat
    11221 tgcttgatat gaagtctaaa ttgcaagcca caaagacttt agcagcagat gttattatgc
    11281 gttctccggt atcttggaag caggagttga ccttagatgc aggtagatca aaaggtgctt
    11341 ctgagaacat gttagctatt gcaaatggtg gcttgattgg gagtgtttca aaagtagagg
    11401 agaactctac tatagtcaac cttctgacaa atacggaaaa tgctgataag atttctgtta
    11461 aaattcaaca tggctctact acaatttatg gaattattat tggctatgac aaggaaaatg
    11521 acgttcttaa aattagccaa ttaaatagta atagcgatat tagtgcggga gataaggtga
    11581 ctactggtgg attaggaaac tttaacgttg ctgatattcc tgttggtgaa gtggttgcca
    11641 caacgcatag tacagactat ttgacacgag aagtaactgt taaattgagt gcagatactc
    11701 ataatgtaga tgtgatagaa ttagtgggga attcataatg agacagttga agcgagttgg
    11761 agtattttta ttgcttcctt tctttgttct aattgacgcc catattagcc agcttctggg
    11821 ctcatttttc ccccatgtac atttggctag tcattttctt tttctatttc tcttatttga
    11881 gacgatagaa gtatcagagt atctctacct agtctattgt tttgttatag gcttggttta
    11941 tgatgtttac tttttccatc taatagggat tacaactctc ttatttatct tattgggagc
    12001 cttccttcat aaattgaata gtgttatttt gttgaatcgt tggacaagaa tgctagctat
    12061 gattgtgctg acattcctgt ttgaaatggg tagttatctt ttggctttta tggtagggtt
    12121 gacagtagat agcatgtcga tttttatagt ctatagcttg gtaccgacga tgattttaaa
    12181 ttttttatgg attactgttt ttcaatttat ttttgaaaaa tattatctat aagaacgaca
    12241 tataaatgta acaaaggcgt aatatttatt aggccttttt ttggtatact agtattgtct
    12301 ttaaaagaag gagtatctac gtaatatgaa gaaaaaaatc ttagcgtcac ttttattaag
    12361 tacagtaatg gtttctcaag tagctgtttt aacaactgcg catgcagaaa cgactgatga
    12421 caaaattgct gctcaagata ataaaattag taacttaaca gcacaacaac aagaagccca
    12481 aaaacaagtt gatcaaattc aggagcaagt atcagctatt caagctgagc agtctaactt
    12541 gcaagctgaa aatgatagat tacaagcaga atctaagaaa ctcgagggtg agattacaga
    12601 actttctaag aacattgttt ctcgtaacca atcgttggaa aaacaagctc gtagtgctca
    12661 aacaaatgga gccgtaacta gctatatcaa taccattgta aactcaaaat caattacaga
    12721 agctatttca cgtgttgctg caatgagtga aatcgtatct gcaaacaaca aaatgttaga
    12781 acaacaaaag gcagataaaa aagctatttc tgaaaaacaa gtagcaaata atgatgctat
    12841 caatactgta attgctaatc aacaaaaatt ggctgatgat gctcaagcat tgactacgaa
    12901 acaggcagaa ctaaaagctg ctgaattaag tcttgctgct gagaaagcga cagctgaagg
    12961 ggaaaaagca agtctattag agcaaaaagc agcagctgag gcagaggctc gtgcagctgc
    13021 ggtagcagaa gcagcttata aagaaaaacg agctagccaa caacaatcag tacttgcttc
    13081 agcaaacact aacttaacag ctcaagtgca agcagtatct gaatctgcag cagcacctgt
    13141 ccgtgcaaaa gttcgtccaa catacagtac aaacgcttca agttatccaa ttggagaatg
    13201 tacatgggga gtaaaaacat tggcaccttg ggctggagac tactggggta atggagcaca
    13261 gtgggctaca agtgcagcag cagcaggttt ccgtacaggt tcaacacctc aagttggagc
    13321 aattgcatgt tggaatgatg gtggatatgg tcacgtagcg gttgttacag ctgttgaatc
    13381 aacaacacgt atccaagtat cagaatcaaa ttatgcaggt aatcgtacaa ttggaaatca
    13441 ccgtggatgg ttcaatccaa caacaacttc tgaaggtttt gttacatata tttatgcaga
    13501 ttaatttaca gagggactcg aatagagccc tcttttcagg ttttaccgtg acaatcccta
    13561 ttaaaaatta tatcaaaata gcttgaaaat attggaaaag tatggtagaa tgaaaattgt
    13621 cgtgtgaacg ataatactca ttcttgatga attgtgaagc agttgccctt gggtcgtttt
    13681 gcgagttgaa gtcaagaaga ggaaaaaaac aaaaaggaga aatactcatg gcagtaattt
    13741 caatgaaaca acttcttgag gctggtgtac actttggtca ccaaactcgt cgctggaatc
    13801 ctaagatggc taagtacatc tttactgaac gtaacggaat ccacgttatc gacttgcaac
    13861 aaactgtaaa atacgctgac caagcatacg acttcatgcg tgatgcagca gctaacgatg
    13921 cagttgtatt gttcgttggt actaagaaac aagcagctga tgcagttgct gaagaagcag
    13981 tacgttcagg tcaatacttc atcaaccacc gttggttggg tggaactctt acaaactggg
    14041 gaacaatcca aaaacgtatc gctcgtttga aagaaattaa acgtatggaa gaagatggaa
    14101 ctttcgaagt tcttcctaag aaagaagttg cacttcttaa caaacaacgt gcgcgtcttg
    14161 aaaaattctt gggcggtatc gaagatatgc ctcgtatccc agatgtgatg tacgtagttg
    14221 acccacataa agagcaaatc gctgttaaag aagctaaaaa attgggaatc ccagttgtag
    14281 cgatggttga caccaatact gatccagatg atatcgatgt aatcatccca gctaacgatg
    14341 acgctatccg tgctgttaaa ttgatcacag ctaaattggc tgacgctatt atcgaaggac
    14401 gtcaaggtga ggatgcagta gcagttgaag cagaatttgc agcttcagaa actcaagcag
    14461 attcaattga agaaatcgtt gaagttgtag aaggtgacaa cgcttaattt atacaaatag
    14521 taattaccta ggagggcggg gcttagcccg gctctcctat tttcaaaaaa tataggagaa
    14581 ttaaaatggc agaaattaca gctaaacttg taaaagagtt gcgtgaaaaa tctggtgccg
    14641 gtgttatgga cgctaaaaaa gcgcttgtag aaacagacgg tgacatcgaa aaagcgattg
    14701 aattgcttcg tgaaaaaggt atggctaagg cagctaagaa agctgaccgt gttgctgcag
    14761 aaggtttgac tggtgtttat gttaacggta atgttgcagc agttattgaa gtaaacgctg
    14821 aaactgactt cgttgcaaaa aacgctcaat tcgttgaatt ggtaaatact acagctaaag
    14881 tcattgctga aggaaaacct gctaacaatg aagaagctct tgctttgata atgccttcag
    14941 gtgaaactct tgaagctgca tacgtatctg caacagcaac tatcggagag aaaatctcat
    15001 tccgtcgctt tgcattgatt gaaaaaacag acgcacaaca ctttggagca taccaacata
    15061 acggtggacg tatcggtgtt atttcagttg ttgaaggtgg agacgaagca cttgctaaac
    15121 aattgtcaat gcacatcgca gcgatgaaac caacagttct ttcttacaaa gaattggatg
    15181 agcaattcgt taaagatgag ttggcacaat tgaatcacgt tatcgaccaa gacaacgaaa
    15241 gccgtgcaat ggttaataag ccagctcttc cacacttgaa gtatggatca aaagctcaat
    15301 taactgatga tgttattgct caagctgaag ctgacatcaa agctgaattg gctgcagaag
    15361 gcaaaccaga aaaaatctgg gacaaaatta ttccaggtaa aatggatcgc ttcatgcttg
    15421 ataacactaa agttgaccaa gcttacacac ttcttgcaca agtttacatc atggatgaca
    15481 gcaagacagt tgaagcatac cttgaatcag ttaacgcttc ggtagttgag tttgctcgct
    15541 ttgaagttgg tgaaggtatc gagaaagctg caaacgactt cgaagctgaa gttgcagcta
    15601 caatggcagc agccttgaat aactaataat agaaaggaag caatttgctt ccttttttgt
    15661 atagggctta tatttttcct gaaattgttt ttcccccagt ctcactcgat tagaataatt
    15721 aaaacaaaaa gccctataat aagggctaag tgcatttagg agactatact tcaaattcat
    15781 agtaagcgcg tcataacaag gtatctatcc taattcccca acttccagta tactagataa
    15841 aaaataatta tcggaggaaa ggtattgtac tatgatgatt caactaagtg atttaggtca
    15901 agttcacatt gtttgtggca agacagatat gaggcaggga atagactcat tagcctatgt
    15961 agttaaaacc cactttgaat tggattcttt ctccggtcaa gtctttctct tttgtggtgg
    16021 acgtaaagac cgctttaaag tcctttactg ggatggtcaa ggattttggc tactatataa
    16081 acgctttgag aacggaaaac tgacttggct aagtacagaa aaggatgtca aagctctcac
    16141 atctgaacaa gtagactggc ttatgaaggg cttttctatc actccccaaa tatagtggtt
    16201 tgaaactaga atagtacacc tctgcttcta aaacattgtt agaaatcgat ttgactgtcc
    16261 tgttcttatt tcattttact ataaattcat cagaaagtcg tgatttctat tgaaatgagg
    16321 actttctttt tatactcatc tgttttcaca aagcattcta gtccatctcc gattaacgat
    16381 ggactttatc acctccttct ccagtccttg tataacatct tggagttgat tcatgacatc
    16441 ttccaaaatt tgaaaggctt tattcttaaa tccacgttta cgaatctctt tccacacttg
    16501 ttcaatgggg ttcatctctg gtgtgtatgg aggaataaat gcaaagccaa tattagtcgg
    16561 aatctttaag gtacttgatt tatgccatat agcattgtcc ataacgagta aaagataatc
    16621 atctggataa gcttgtgaaa tctcctattc ctaaagcccc tttagcgcat aactttggct
    16681 cagcttctat tatcgctcac accatccatc agaagtttaa tctgaaggta cccaattatc
    16741 gccaagaaga agattgggct aggatgggtt taccaatcac acgtaaggaa atctctaatc
    16801 ggcatatcaa gacgagtcaa tactatttgg agccccttta taacctcttg cgagagagac
    16861 tattgactca gcccttactt catgcggatg aaacttctta tagggtgcta gagagtgata
    16921 gtcagctgac ttactattgg acttttttgt ctgggaaagc tgagaaacaa gggattacgc
    16981 tttaccatca tgtcctaatc gatttgttca tatcttattt caatccatta taaatagtga
    17041 gaaatatcta tcctatcttc tagaatgtct tccaaacgtg gaaactctcg taaacaaaga
    17101 ggttttagag gcctatttac catggactaa agttgtacaa gaaaagtgca aataagaaat
    17161 ctccagatta ggaactatcc gtgagttctc tagtctggag atttttcaat agacttcgtt
    17221 attggacggt tacaattcat aaagtgctgt agagagataa cgttcaccgt tatctggtgc
    17281 tagggcaagg acttttttac ctgtacctaa ttttttggca acctcgatgg ctccgtagat
    17341 agctgcagct gaggaaatcc ctacaaggaa gccttctttt ccaccaattt cacgtccgag
    17401 tgcaagagcg tcatctgatg ttacacgaac gataccatca taggctttag tatcaagtgt
    17461 atcaggaata aatccagctg agataccttg aattttgtga ggaccaggtt tttcaccaga
    17521 tagaatagca gattcatctg cttctactgc aaaaacttga atgttagaat tttctgattt
    17581 gagtgcatga gaaacaccag aaatcgttcc accagtacct actccagcaa caaaggcatc
    17641 taatccatct ttaccgaaag cagctagtat ctcagctcct gttgttcttt cgtgtacttc
    17701 tggattagct ggattgtcaa attgaagagg aaggaaacca tcacgttcag cagcgatttc
    17761 ttgagcctta gcaatagcac ctttcattcc ctcgctacca ggagttagga cgagttcagc
    17821 accataagct tggataattt tacgtcgttc tacactcata gtttcaggca taacgatgac
    17881 gactttatac cctttagcag cacctaccca tgaaagtcca ataccggtgt ttccacttgt
    17941 tgcttcaaca atagtagaac caagtttcag aataccatct tgttcagctt tttcaatcat
    18001 gctaagggca atacggtctt ttacagatga accaggatta aatgcttcaa gctttatata
    18061 gacgtctgca gcaccttctg gcacgatgtt gttaagttta acaatcggtg tttgaccgat
    18121 taattcagta atgttgttat aaatagacat atgaatacct ctttgtataa gatatcttta
    18181 gtataacgct atccatacca tttgtaaaat atagaaatcc tatcgaagcg ataggatttc
    18241 tatatatcat agatcaaagt cattaatttt caagtgattg cgttcagtta attctagtaa
    18301 ataggtgtga aggaaaacga tatcaggttt cgtttgaatt gcttcatttt ctagtatatt
    18361 ttggtacgca tctttttatt ttgctcgcta aagtagttgt gagaatgtca acgaaacgct
    18421 gtattattca ttgtttacac taagtttaca ggaacttcaa cctctcgtaa accttggtca
    18481 gttaaagtga cttttccatt aaaaaactcc acaagtgcag ctttaatagt ttctttttct
    18541 tctttatcaa cataaatcat cgtatcgact tgatctgtaa agtttgtatc cagctccatg
    18601 agatcatgtt ctttaaggaa gttactgtac tcttggtact gagcataaga catttgaata
    18661 gcaatgccag cctgttcttt tatttcaata ataccaattt ctttgacagc taaggcgaca
    18721 ctgctggtgt aagcacgaat tagtcctcca gcgcctagtt taataccacc aaagtagcgt
    18781 gtcacgacca cacagacatt ggtgagattg tgattttcta gtaccccaag catgggaaca
    18841 ccagcagtac cactaggctc accatcatca cttgtacgtt taatttcact acgttctcca
    18901 ataataaagg cagagcagtt atgtgtcgct ttgtagtgtt cttttttgat ggcagtaatg
    18961 aagtcacgag cctcttcttc gctataaaca cgcttggcat ggcagataaa gcgagatttt
    19021 ttgatttctt cttggacttg gccgtcctct ttaattgtcc taaattccat gatttaattg
    19081 tactaaaaaa tcatctaaag tgctagtttt tacgaataaa gaagtatgaa agtaaattta
    19141 gattatctcg gtcgtttatt tactgagaat gaattaacag aagaagaacg tcagttggcg
    19201 gagaaacttc cagcaatgag aaaggagaag gggaaacttt tctgtcaacg ttgtaatagt
    19261 actattctag aagaatggta tttgcccatc ggtgcttact attgtcgaga gtgcttgctg
    19321 atgaagcgag tcagaagtga tcaaacttta tactattttc cgcaggagga ttttccgaag
    19381 caagatgttc tcaaatggcg cggccaatta actccttttc aagagaaggt gtcagaggga
    19441 ctgcttcaag cagtagacaa gcaaaagcca accttagttc atgcggtaac aggagctgga
    19501 aagacagaaa tgatttatca agtagtggct aaagtgatca atgcgggtgg tgcagtgtgt
    19561 ttggctagtc ctcgcataga tgtttgtttg gagctgtaca agcgcctgca acaggatttt
    19621 tcttgcggga tagctttgct acatggagaa tcggaacctt attttcgaac accactagtt
    19681 gttgcaacaa cccatcagtt attgaagttt tatcaagctt ttgatttgct gatagtggat
    19741 gaagtagatg cttttcctta tgttgataat cccacgcttt accatgctgt caagaatagt
    19801 gtaaaggaga atggattgag aatcttttta acagcgactt cgaccaatga gttagataaa
    19861 aaggtccgtt taggagaact aaaaagactg aatttaccga gacggtttca tggaaatccg
    19921 ttgattattc caaaaccaat ttggttatcg gattttaatc gctacttaga caagaatcgt
    19981 ttgtcaccaa agttaaagtc ctatattgag aagcagagaa agacagctta tccgttactc
    20041 atttttgctt cagaaattaa gaaaggggag cagttagaag aaatcttaca ggagcaattt
    20101 ccaaatgaga aaattggctt tgtatcttct gtaacagagg atcgattaga gcaagtacaa
    20161 gcttttcgag atggagaact gacaatactt atcagtacga caatcttgga gcgtggagtt
    20221 accttccctt gtgtggatgt tttcgtagta gaagccaatc atcgtttgtt taccaagtct
    20281 agtttgattc agattggtgg acgagttgga cgaagcatgg atagaccgac aggagatttg
    20341 cttttcttcc atgatgggtt aaatgcttca atcaagaagg cgattaagga aattcagatg
    20401 atgaataagg aggctggtct atgaagtgct tgttatgtgg gcagactatg aagactgttt
    20461 taacttttag tagtctctta cttctgagga atgatgactc ttgtctttgt tcagactgtg
    20521 attctacttt tgaaagaatt ggggaagaga actgtccaaa ttgtatgaaa acagagttgt
    20581 caacaaagtg tcaagattgt caattttggt gtaaagaagg agttggagtc agtcatagag
    20641 cgatttttac ttacaatcaa gctatgaagg attttttcag tcggtataag tttgatggag
    20701 acttcctgtt aagaaaagtt ttcgcttcat ttttaagtga ggagttgaaa aagtacaaag
    20761 agtatcaatt tgttgtaatt cccctaagtc ctgatagata tgctaataga ggatttaatc
    20821 aggttgaggg cttggtagag gcagcaggct ttgagtatct ggatttatta gagaaaagag
    20881 aagagagagc cagttcttct aaaaatcgtt cagagcgctt ggggacagaa cttcctttct
    20941 ttattaaaag tggagtcact attcctaaaa aaatcctact tatagatgat atctatacta
    21001 caggagcaac tataaatcgt gttaagaaac tgttggaaga agctggtgct aaggatgtaa
    21061 aaacattttc ccttgtaaga tgaggaaaaa atttgcaaaa atagaatgaa agcgttataa
    21121 taaaatcata aaaacaaaaa tgtttagaaa gaaggtactc atatgattaa atatagtatc
    21181 cgtggtgaaa acctagaagt aacagaagca attcgtgatt atgtagtttc taaactcgaa
    21241 aagatcgaaa agtacttcca accagaacaa gagttggatg cccgaattaa cttaaaagtt
    21301 tatcgtgaaa aaacggctaa agtggaagta acgattccgc ttggatctat tactctccgc
    21361 gcagaagatg tatctcaaga tatgtatggt tcaattgacc ttgtaactga taaaattgaa
    21421 cgtcagattc gtaaaaataa aacaaaaatc gagcgtaaaa ataaaaataa ggtagcaact
    21481 ggtcaattat ttacagatgc tttggtggaa gattcaaata ttgtccagtc taaagttgtt
    21541 cgttcaaaac aaattgattt aaaaccaatg gatttggaag aagcaattct acaaatggat
    21601 ttattggggc atgatttctt tatctatgtg gatgttgaag atcagacaac caatgtgatt
    21661 tatcgtcgtg aggatggcga aattggtttg ttagaggtta aagaatctta atttcaatat
    21721 gtgtaaaggt aggtttactg aattgtaaac tacctttttc ttataattga tagaattact
    21781 gattacactt ttaaaaagtc gctttttgag gggtattatg gtataatggg tgccaagagg
    21841 ttttgaatga aaaaatttta tgtaagtcca atttttccta ttctagtagg attgattgcg
    21901 tttggagtct tatccacttt cattattttt gttaataata atctgttgac ggttttaatt
    21961 ttgtttcttt ttgtaggagg ctatgttttt ttatttaaga aactgagagt gcattataca
    22021 aggagtgatg tagaacagat acagtatgta aaccaccaag cggaagaaag tttgacagct
    22081 ctattggaac agatgcctgt aggtgttatg aaattgaatt tatcttctgg agaggttgag
    22141 tggtttaatc cctatgctga attgattttg accaaggaag atggtgattt tgatttagaa
    22201 gctgttcaaa cgattatcaa ggcttcagta ggaaatccgt ctacttatgc caagcttggt
    22261 gagaagcgtt atgctgttca tatggatgct tcttccggtg ttttgtattt tgtagatgta
    22321 tccagggaac aagccataac agatgaattg gtaacaagta gaccagtgat tgggattgtc
    22381 tctgtggata attatgatga tttggaggat gcaacttctg agtcagatat tagtcaaatc
    22441 aatagttttg tagctaattt tatatcagag ttttcagaaa aatacatgat gttttctcgt
    22501 cgggtaagta tggatcgatt ttatctattt actgactaca cggtgcttga gggcttgatg
    22561 aatgataaat tttctgttat tgatgctttc agagaagagt cgaaacagag acagttgccc
    22621 ttgaccttaa gtatgggatt ttcttatggc gatggaaatc atgatgagat agggaaagtt
    22681 gctttgctca atttgaactt ggctgaagta cgtggtggcg accaggtggt tgttaaggaa
    22741 aacgacgaaa cgaaaaatcc agtttatttt ggtggtgggt ctgctgcttc aatcaagcgt
    22801 acacggactc gtacgcgcgc tatgatgaca gctatttcag ataagattcg gagtgtagat
    22861 caggtttttg tagtcggtca caaaaattta gacatggatg ctttgggctc tgctgtaggt
    22921 atgcagttgt tcgccagcaa tgtgattgaa aatagctatg ctctttatga tgaagaacaa
    22981 atgtctccag atattgaacg agctgtttca ttcatagaaa aagaaggagt tacgaagttg
    23041 ttgtctgtta aggatgcaat ggggatggtg accaatcgtt ctttgttgat tcttgtagac
    23101 cattcaaaga cagccttaac attatcaaaa gaattttatg atttatttac ccaaaccatt
    23161 gttattgacc accatagaag ggatcaggat tttccagata atgcggttat tacttatatc
    23221 gaaagtggtg caagtagtgc cagtgagttg gtaacggaat tgattcagtt ccagaattct
    23281 aagaaaaatc gtttgagtcg tatgcaagca agtgttttga tggctggtat gatgttggat
    23341 actaaaaatt tcacctcgcg agtaactagt cggacatttg atgttgctag ctatctcaga
    23401 acgcgcggaa gtgatagtat tgctatccag gaaatcgctg cgacagattt tgaagaatat
    23461 cgtgaggtta atgaacttat tttacagggg cgtaaattag gttcagatgt actaatagca
    23521 gaggctaagg acacgaaatg ctatgataca gttgttatta gtaaggcagc agatgccatg
    23581 ttagccatgt caggtattga agcgagtttt gttcttgcga agaatacaca aggatttatc
    23641 tctatctcag ctcgaagtcg tagtaaactg aatgtacaac ggattatgga agagttaggc
    23701 ggtggaggcc actttaattt ggcagcagct caaattaaag atgtaacctt gtcagaagca
    23761 ggtgaaaaac tgacagaaat tgtattaaat gaaataaagg aaaaggagaa agaagaatga
    23821 aagtaatctt tttagcagat gttaaaggaa aaggtaaaaa aggcgaaatt aaggaagtac
    23881 caacagggta tgcgcaaaac tttcttatca aaaagaatct agccaaagaa gcgactgctc
    23941 aagctgtagg tgaacttcgt ggtaaacaaa aatcggaaga aaaagctcac gctgagatga
    24001 ttgcagaagg gaaagcaatt aaagcacaac ttgaagcaga agaaactgtt gtagaatttg
    24061 ttgaaaaagt tggtccagat ggtcgtacct ttggttctat taccaataag aagattgcag
    24121 aagaattaca aaagcaattt ggaattaaga ttgataaacg tcatattcaa gtacaagctc
    24181 cgattcgagc ggttggtttg attgatgtgc cagtgaaaat ctatcaagat atcacaagtg
    24241 taatcaatct tcgtgtgaaa gaaggataag tttacacctt cttgacaaga ttgtaaaagg
    24301 aagggaagtc tgatggcaga agtagaagag ttacgagtac aacctcaaga tatcttagct
    24361 gagcaatccg ttttaggggc tatctttatt gatgagagta aacttgtttt tgtgcgagaa
    24421 tacattgagt ctcgggactt ttttaagtat gcccatcgtt tgattttcca agccatggtc
    24481 gatttatccg atcgtggtga tgccatagat gcaacaacgg ttcgtactat ccttgataat
    24541 caaggtgatt tacagaatat tggtggcttg tcttacttgg ttgagattgt caattctgtg
    24601 ccaacttctg ctaatgcgga gtattatgct aagattgttg cagaaaaagc aatgctacgt
    24661 cgtttaattg ccaagttgac agagtctgtc aaccaagctt acgaagcgtc acaaccagct
    24721 gatgaaatta ttgctcaggc agaaaaaggg ctgattgatg tcagtgaaaa tgcaaatcga
    24781 agcgggttta agaacattcg agatgtgttg aatctcaact ttggaaatct ggaagctcgc
    24841 tcgcaacaaa cgaccgatat tacaggtatt gcgacaggtt atcgtgattt ggatcatatg
    24901 acaacaggac ttcatgagga ggagttgatt atcttagcag ctcgtccagc agttggtaag
    24961 acagcatttg ccttgaatat cgctcagaat attgggacta agttggacaa aacggttgct
    25021 attttttcac tcgaaatggg tgcggaaagc ttggtagacc gtatgttagc tgcagaaggc
    25081 ttggtggagt cacattctat ccgtacaggg caattgacag atgaggagtg gcaaaaatat
    25141 actattgctc agggtaatct agctaacgcc agtatctata tcgatgatac gccaggtatt
    25201 cggattacag agattcgttc tcgttctcgt aaattggctc aagaaactgg aaatcttggt
    25261 ttgattttga tagactattt gcaacttatc acgggaactg gtcgagaaaa tcgtcaacaa
    25321 gaagtttctg aaatttctcg tcagttgaaa atactagcca aggaattgaa ggttccagta
    25381 atcgctctga gtcagctttc tcgtggtgta gaacaacgtc aggacaagag accggtcttg
    25441 tctgatattc gtgaatctgg gtctattgag caggacgctg atatcgtagc ttttctctat
    25501 cgcgatgact actatgaacg tggtggtgaa gaagaggagg gtatcccaaa taataaggtg
    25561 gaagttatta tcgagaaaaa ccgtagtgga gctcgtggaa cagtggaatt gattttccaa
    25621 aaagaataca ataaattttc aagtatctca aagagggagg cataagatgt cagatgcatt
    25681 tacagatgta gccaagatga aaaaaatcaa agaagaaatc aaggcacatg agggacaagt
    25741 cgtagaaatg actttggaga atggtcgtaa gcgccaaaaa aatagattgg gtaagctaat
    25801 tgaagtttat ccatccctat ttattgtgga gtttggggat gtggaaggag ataaacaagt
    25861 taatgtttac gttgaatcct ttacttactc agatattctt acagaaaaga atttgattca
    25921 ttatcttgac taaagtgaga aattttctca ctttttcttt tttctccgaa taatttaggt
    25981 gaaggcaatc atcgctttat attatttttt aaggaggaag aatgaaaatt ttaccgttta
    26041 tagcaagagg aacaagttat tacttgaaga tgtcagttaa aaagcttgtt ccttttttag
    26101 tagtaggatt gatgctagca gctggtgata gtgtctatgc ctattccaga ggaaatggat
    26161 cgattgcgcg tggggatgat tatcctgctt attataaaaa tgggagccag gagattgatc
    26221 agtggcgcat gtattctcgt cagtgtactt cttttgtagc ctttcgtttg agtaatgtca
    26281 atggttttga aattccggca gcttatggaa atgcgaatga atggggacat cgtgctcgtc
    26341 gggaaggtta tcgtgtagat aatacaccga cgattggttc cattacttgg tctactgcag
    26401 gaacttatgg tcatgttgcc tgggtgtcaa atgtaatggg agatcagatt gagattgagg
    26461 aatataacta tggttataca gaatcctata ataaacgaat tataaaagca aacacgatga
    26521 caggatttat tcattttaaa gatttggatg gtggcagtgt tgggaatagt caatcctcaa
    26581 cttcaacagg cggaactcat tattttaaga ccaagtctgc tattaaaact gaacccctag
    26641 ttagtgcaac tgtgattgat tactattatc ctggagagaa ggttcattat gatcaaattc
    26701 tcgaaaaaga cggctacaag tggttgagtt atactgccta taatggaagc tatcgttatg
    26761 ttcaattgga ggctgtgaat aaaaatcctc taggtaattc tgttctttct tcaacaggtg
    26821 gaactcatta ttttaagacc aagtctgcta tcaaaactga acccctagtt agtgcaactg
    26881 tgattgatta ctattatcct ggagagaagg ttcattatga tcagatactt gaaaaagacg
    26941 gctacaagtg gttgagttat acggcttata acggaagtcg tcgctatata cagctagagg
    27001 gagtgacttc ttcacaaaat tatcagaatc aatcaggaaa tatctctagc tatggatcca
    27061 ataatagttc aactgtcggt tggaagaaaa taaatggtag ttggtatcat ttcaaatcaa
    27121 atggttctaa atcaacagga tggctgaaag atggttctag ctggtattat ttgaaattat
    27181 ctggtgaaat gcagacagga tggttaaagg agaatggctc gtggtattat ctgggtagtt
    27241 caggggcaat gaaaacaggc tggtaccagg tctctggtaa gtggtattat tcttactctt
    27301 caggcgcctt agctgttaat acgacggtgg atggctacag agtaaacagt gatggagaac
    27361 gagtatagaa aattggagta ggagaaattt cctgctcttt tctgtaagca gtttccttga
    27421 catttttctt attttgcgct atcatatata catataatat atgggagtct gtgtacagtc
    27481 tgagaggaag tgttaaactt cgaccgcacc tgatctgggt aatgccagcg gagggaacga
    27541 tacttagtct aattttgcac cttttccatg tatggtaaag gtttttcttt tttttaaaag
    27601 gaaaacgaga agaggaggtt cttatgaaag caagcattgc cttgcaagtt ttacccctag
    27661 cacaggggat tgatcggata gctgttattg atcaggtcat tgcttatctg caaactcaag
    27721 aagtgacgat ggtagtgaca ccatttgaaa cggtcttgga aggggagttt gatgagctta
    27781 tgcgcattct aaaagaagcg ctggaagtgg cagggcagga ggcagacaat gtctttgcca
    27841 atgtcaaaat aaatgtagga gagattttaa gtattgatga gaaacttgaa aagtatactg
    27901 agacgacaca ttagtctatt gggctttctc ggagtattgt caatctggca gttagcaggt
    27961 tttcttaaac ttctccccaa gtttatcctg ccgacacctc ttgaaattct ccagcccttt
    28021 gttcgtgaca gagaatttct ctggcaccat agctgggcga ccttgagagt ggctttactg
    28081 gggctgattt tgggagtttt gattgcctgt cttatggctg tgctcatgga tagtttgact
    28141 tggctcaatg acctgattta ccctatgatg gtggtcattc agaccattcc gaccattgcc
    28201 atagctccta tcctggtctt gtggctaggt tatgggattt tgcccaagat tgtcttgatt
    28261 atcttaacga caacctttcc catcatcgtt agtattttgg acggttttag gcattgtgac
    28321 aaggatatgc tgaccttgtt tagtctgatg cgggccaagc cttggcaaat cctgtggcat
    28381 tttaaaatcc cggttagcct gccttacttt tatgcaggtc tgagggtcag tgtctcctac
    28441 gcctttatca caactgtggt atctgagtgg ttgggaggtt ttgaaggtct tggtgtttat
    28501 atgattcagt ctaaaaaact gtttcagtat gataccatgt ttgccattat tattctggtg
    28561 tcgattatca gtcttttggg tatgaagctg gtcgatatca gtgaaaaata tgtgattaaa
    28621 tggaaacgta cttaaaatag agcgtttttg aaaaagaaaa gaggaaatca aaatgaagaa
    28681 aacatggaaa gtgtttttaa cgcttgtaac agctcttgta gctgttgtgc ttgtggcctg
    28741 tggtcaagga actgcttcta aagacaacaa agaggcagaa cttaagaagg ttgactttat
    28801 cctagactgg acaccaaata ccaaccacac agggctttat gttgccaagg aaaaaggtta
    28861 tttcaaagaa gctggagtgg atgttgattt gaagttgcca ccagaagaaa gttcttctga
    28921 cttggttatc aacggaaagg caccatttgc agtgtatttc caagactaca tggctaagaa
    28981 attggaaaaa ggagcaggaa tcactgccgt tgcagctatt gttgaacaca atacatcagg
    29041 aatcatctct cgtaaatctg ataatgtaag cagtccaaaa gacttggttg gtaagaaata
    29101 tgggacatgg aatgacccaa ctgaacttgc tatgttgaaa accttggtag aatctcaagg
    29161 tggagacttt gagaaggttg aaaaagtacc aaataacgac tcaaactcaa tcacaccgat
    29221 tgccaatggc gtctttgata ctgcttggat ttactacggt tgggatggta tccttgctaa
    29281 atctcaaggt gtagatgcta acttcatgta cttgaaagac tatgtcaagg agtttgacta
    29341 ctattcacca gttatcatcg caaacaacga ctatctgaaa gataacaaag aagaagctcg
    29401 caaagtcatc caagccatca aaaaaggcta ccaatatgcc atggaacatc cagaagaagc
    29461 tgcagatatt ctcatcaaga atgcacctga actcaaggaa aaacgtgact ttgtcatcga
    29521 atctcaaaaa tacttgtcaa aagaatacgc aagcgacaag gaaaaatggg gtcaatttga
    29581 cgcagctcgc tggaatgctt tctacaaatg ggataaagaa aatggtatcc ttaaagaaga
    29641 cttgacagac aaaggcttca ccaacgaatt tgtgaaataa tgacagaaat tagactagag
    29701 cacgtcagtt atgcctatgg tcaggagagg attttagagg atatcaacct acaggtgact
    29761 tcaggcgaag tggtttccat cctaggccca agtggtgttg gaaagaccac cctctttaat
    29821 ctaatcgctg ggattttaga agttcagtca gggagaattg tccttgatgg tgaagaaaat
    29881 cccaaggggc gcgtgagtta tatgttgcaa aaggatctgc tcttggagca caagacggtg
    29941 cttggaaata tcattctgcc cctcttgatt caaaaggtgg ataaggcaga agctatttcc
    30001 cgagcggata aaattcttgc gaccttccag ctgacagctg taagagacaa gtatcctcat
    30061 gaacttagcg gtgggatgcg ccagcgtgta gccttactcc ggacctacct ttttgggcac
    30121 aagctctttc tcttagatga ggcctttagc gccttggatg agatgacaaa gatggaactc
    30181 cacgcttggt atcttgagat tcacaagcag ttgcagctaa caaccctgat catcacgcat
    30241 agtattgagg aggccctcaa tctcagcgac cgcatctata tcttgaaaaa tcgccctggg
    30301 cagattgttt cagaaattaa actagattgg tctgaagatg aggacaagga agtccaaaag
    30361 attgcctaca aacgtcaaat tttggcggaa ttaggcttag ataagtagaa aaatagggag
    30421 ttggtgaaga ttatccttta ccagcgccct ttttctttta aaaatgagaa aatttcggta
    30481 taatagtcaa acaaggtcaa ggtttaaaga gagaggtggg tttgttatga gatttaaaaa
    30541 tacatcggat catattgagg cctacatcaa ggcgatttta gatcaatctg gtatcgtgga
    30601 gttgcaacgg agtcagttgg cagatacctt tcaggttgtt cctagtcaga ttaactacgt
    30661 gatcaagaca cgctttacgg aaagtagagg ctacttggtt gaaagtaagc gtggtggcgg
    30721 aggctacatt cgtataggac ggattgagtt ttctagtcat catgaaatgc tccgggagct
    30781 gctttactcg attggtgagc gagtcagtca agaaatttat gaggatattc tccagctttt
    30841 ggttgagcag gaattgatga ccaagcagga gatgaatttg ctagtatcag tagctttgga
    30901 tcgcgtttta ggagaagaag ctccagttgt tcgagcaaac atgctacgtc agatcataca
    30961 agaagtagat agaaaaggga agtaagatga actattcaaa agcattgaat gaatgtatcg
    31021 aaagtgccta catggttgct ggacattttg gagctcgtta tctagagtct tggcacttgt
    31081 tgattgccat gtctaatcac agttatagtg tagcaggggc aactttaaat gattatccgt
    31141 atgagatgga ccgtttagaa gaggtggctt tggaactgac tgaaacggac tatagccagg
    31201 atgaaacctt tacggaattg ccgttctccc gtcgtttgca ggttcttttt gatgaagcag
    31261 agtatgtagc gtcagtggtc catgctaagg tactagggac agagcacgtc ctctatgcga
    31321 ttttgcatga tggcaatgcc ttggcgactc gtatcttgga gagggctggt ttttcttatg
    31381 aagacaagaa agatcaggtc aagattgctg ctcttcgtcg aaatttagaa gaacgggcag
    31441 gctggactcg tgaagatctc aaggctttac gccaacgcca tcgtacagta gctgacaagc
    31501 aaaattctat ggccaatatg atgggcatgc cgcagactcc tagtggtggt ctcgaggact
    31561 atacgcatga tttgacagag caagcgcgtt ctggcaagtt agaaccagtc atcggtcggg
    31621 acaaggaaat ctcacgtatg attcaaatct tgagccgtaa gactaagaac aaccctgtct
    31681 tggttgggga tgctggtgtc gggaaaacag ctctggcgct tggtcttgct cagcgtattg
    31741 ctagtggtga cgtgcctgcg gaaatggcta agatgcgcgt gttagaactt gatttgatga
    31801 atgtcgttgc agggacacgc ttccgtggtg actttgaaga acgcatgaat aatatcatca
    31861 aggatattga agaagatggc caagtcatcc tctttatcga tgaacttcac accatcatgg
    31921 gttctggtag cgggattgat tcgactctgg atgcggccaa tatcttgaaa ccagccttgg
    31981 cgcgtggaac tttgagaacg gttggtgcca ccactcagga agaatatcaa aaacatatcg
    32041 aaaaagatgc agcactttct cgtcgtttcg ctaaagtgac gattgaagaa ccaagtgtgg
    32101 cagatagtat gactatttta caaggtttga aggcgactta tgagaaacat caccgtgtac
    32161 aaatcacaga tgaagcggtt gaaacagcgg ttaagatggc tcatcgttat ttaaccagtc
    32221 gtcacttgcc agactctgct atcgatctct tggatgaggc ggcagcaaca gtgcaaaata
    32281 aatcaaagca tgtaaaagca gacgattctg acttgagtcc agctgacaag gccttgatgg
    32341 atggcaagtg gaaacaggca gcccagctaa tcgcaaaaga agaggaagtg cctgtctata
    32401 aagacttggt gacagaatct gatattttga ccaccttgag tcgcttgtca ggtatccccg
    32461 ttcaaaaact gactcagact gatgccaaga aatacttaaa cttggaagct gaactgcaca
    32521 aacgtgtcat cggtcaagac caagctgttt caagtattag tcgtgccatt cgccgcaatc
    32581 agtcaggaat tcgcagtcac aagcgtccga tcggttcctt tatgttccta ggacccacag
    32641 gtgtcggtaa gaccgagttg gccaaggctt tggcagaagt tctctttgat gacgaatcag
    32701 cccttatccg ctttgatatg agtgagtata tggagaaatt cgcagccagc cgtctaaatg
    32761 gagctcctcc aggctatgtg ggttacgaag aaggtgggga gttgacagag aaggttcgca
    32821 ataaacccta ttccgttctc ctctttgatg aggtagagaa ggcccatcca gatatcttta
    32881 atgttctctt gcaggttctg gatgacggtg tcttgacaga tagcaaggga cgcaaggtcg
    32941 atttttcaaa taccattatc attatgacat cgaacttagg tgcgactgcc cttcgtgatg
    33001 ataagactgt tggttttggg gctaaggata ttcgttttga ccaggaaaat atggaaaaac
    33061 gcatgtttga agaactgaaa aaagcttata gaccggaatt catcaaccgt attgatgaga
    33121 aggtggtctt ccatagccta tctagtgacc atatgcagga agtggtgaag attatggtca
    33181 agcctttagt ggcaagtttg gctgaaaaag gcattgactt gaaattacaa gcttcagctc
    33241 tgaaattgtt agcaaatcaa ggatatgacc cagagatggg agctcgccca cttcgcagaa
    33301 ccctgcaaac agaagtggag gacaagttgg cagaacttct tcttaaggga gatttagtgg
    33361 caggcagcac acttaagatt ggtgtcaaag caggccagtt aaaatttgat attgcataaa
    33421 agaataaaag tatcagcatc tgaccataag tcacagtgga gtgaaactca atgaaaatca
    33481 aagagcaaac taggcagcta gccgcaggtt gctcaaaaca ctggtttgag gttgcagata
    33541 gagctgacgt ggtttgaaga gattttcgaa gagtatgaaa ctaaaaccta tagcttctaa
    33601 acgatccgtg gttttcacca ttcaacacaa aattcatatg tttattaccc tccgtcgtat
    33661 ttgtcttaga gcgtgtgtag tagaaaaaga gcagtcttat ctgaaatttt tattctttca
    33721 aaagagacct gtttcttttt tgcatgtcaa atccgttcta gctggtattt gaaaaatcaa
    33781 actaatattc aataaaaatc aaagaacaaa ctaggaagct agccgcaggt tgctcaaaac
    33841 actgttttga ggttgtagat agagctgacg tagtttgaag agattttcga agagtataag
    33901 ctgcaagatg aatgattttc ttgtattgac gttgttgttg acaaaaagta gcggataaat
    33961 gaaatccatt ccattatcat agatgatagg ctggtaggaa attttcaaat agcatacagg
    34021 aaatagatgt atggagttct ggtagtagaa agggagagag atgaacattt tagttgcaga
    34081 tgacgaggaa atgattagag aaggaattgc agcatttctg acagaagagg gttatcatgt
    34141 cattatggct aaggatggac aagaggtctt ggaaaaattt caagatctcc ctatccatct
    34201 catggtactg gatttaatga tgcctaggaa gagtggtttt gaagtgttaa aagaaatcaa
    34261 tcaaaagcac gatattcctg tcatcgtctt gagtgctctg ggagatgaaa ctactcagtc
    34321 acaggtattt gatctctatg ctgatgatca tgtgacaaaa cctttttctt tggtactgct
    34381 tgtcaagcgt attaaggcgc ttatcagacg ttactacgtc atagaggatc tttggcgata
    34441 tcaggatgta acagtggatt ttacctctta caaagcacat tataaaaatg aagaaattga
    34501 tctcaaacca aaggaattac tggtactaaa gtgtttgatt cagcataaaa atcaagtttt
    34561 aagtagagag cagatattgg aagaaatttc aaaagatgta gctgatttac cttgtgatag
    34621 ggtcgttgat gtctatattc gtactcttcg caaaaaatta gctttagatt gtatcgtgac
    34681 tgtgaaaaat gttgggtata agattagctt atgataaaaa atcctaaatt attaaccaag
    34741 tcttttttaa gaagttttgc aattctaggt ggtgttggtc tagtcattca tatagctatt
    34801 tatttgacct ttccttttta ttatattcaa ctggaggggg aaaagtttaa tgagagcgca
    34861 agagtgttta cggagtattt aaagactaag acatctgatg aaattccaag cttactccag
    34921 tcttattcaa agtccttgac catatctgct caccttaaaa gagatattgt agataagcgg
    34981 ctccctcttg tgcatgactt ggatattaaa gatggaaagc tatcaaatta tatcgtgatg
    35041 ttagatatgt ctgttagtac agcagatggt aaacaggtaa ccgtgcaatt tgttcacggg
    35101 gtagatgtct acaaagaagc aaagaatatt ttgcttttgt atctcccata tacatttttg
    35161 gttacaattg ctttttcctt tgttttttct tatttttata ctaaacgctt gctcaatcct
    35221 cttttttaca tttcagaagt gactagtaaa atgcaagatt tggatgacaa tattcgtttt
    35281 gatgaaagta ggaaagatga agttggtgaa gttggaaaac agattaatgg tatgtatgag
    35341 cacttgttga aggttattca tgagttggaa agtcgtaatg agcaaattgt aaaattgcaa
    35401 aatcaaaagg tttcctttgt ccgtggagca tcacatgagt tgaaaacccc tttagccagt
    35461 cttagaatta tcctagagaa tatgcagcat aatattggag attacaaaga tcatccaaaa
    35521 tatattgcaa agagtataaa taagattgac cagatgagcc acttattgga agaagtactg
    35581 gagtcttcta aattccaaga gtggacagag tgtcgtgaga ccttgactgt taagccagtt
    35641 ttagtagata ttttatcacg ttatcaagaa ttagctcatt caataggtgt tacaattgaa
    35701 aatcaattga cagatgctac cagggtcgtc atgagtctta gggcattgga taaggttttg
    35761 acaaacctga ttagtaatgc aattaaatat tcagataaaa atgggcgtgt aatcatatcc
    35821 gagcaagatg gctatctctc tatcaaaaat acatgtgcgc ctctaagtga ccaagaacta
    35881 gaacatttat ttgatatatt ctatcattct caaatcgtga cagataagga tgaaagttcc
    35941 ggtttgggtc tttacattgt gagtaatatt ttagaaagct atcaaatgga ctatagtttt
    36001 ctcccttatg aacacggtat ggaatttaag attagcttgt agacagatta gttttttatt
    36061 aaagttcaca tagggttaac ataagtgtat tattctttat atagataaaa atatagataa
    36121 aagaaaggat actaatatgg tattagcgat tattttagta acattcctta ttcgattgat
    36181 ttttttaaag cgttcgatag agaatgagaa acgaatcctt agcaatggcg ggaaagaatt
    36241 tggagttgag aatacaaaac gattaacgtt ggctcatatt gttttttatc tctcttgcct
    36301 cgttgaagca atggtgcaca agacaatttt tgatggcatg ggcatggttg gtttagtctt
    36361 gcttattttt tctatgctga tgttgatgtt ggtgattcac ttgttgggag atatttggac
    36421 agtgaagctt atgcttgtca ataatcacaa atatgtagat catatcttgt ttaggacagt
    36481 aaaacatcct aattactttt taaatattct tcctgagttg attggcttga ccttgttgag
    36541 tcatgcttat gtgacttttg ttttagtttt tccagtttat gcagttattt tgtatcgacg
    36601 aatagctgaa gaggaaaagc tattacatga agttataatc ccaaatggaa gcataaagag
    36661 ataaatacaa aattcgattt atatacagtt catattgaag tgatatagta aggttaaaga
    36721 aaaaatatag aaggaaataa acatgtttgc atcaaaaagc gaaagaaaag tacattattc
    36781 aattcgtaaa tttagtattg gagtagctag tgtagtagtt gctagcttgt tcttaggagg
    36841 agtagttcat gcagaagagg ttggtggtag gaataccccc acggttacat ctagtgggca
    36901 agatatatcg aagaagtatg ctgatgaagt cgagtcgcat ctaaaaaaaa tattgagtga
    36961 gatccaaaca caattagata gaaaacgaca taccaaaact gtagcgctaa ttaacgagtt
    37021 gcaaaacatt aagaaaacgt atttgtataa tttaaatgtt ttaaaagaga agtctgagtt
    37081 gccgtcaaaa ataaaagcaa agttagaagt agcttttgat cagtttaaaa aagatacatt
    37141 gaaaccagga gaaaaggtag cagaagctga gaagaaagtt gcagaagcta agaaaaaagc
    37201 cgaggatcaa aaagaa
//
LOCUS       DAVHSY010000018        34500 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.018, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000018 DAVHSY010000000
VERSION     DAVHSY010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34500
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.018"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            590..1042
                     /locus_tag="VVR43_001110"
     CDS             590..1042
                     /locus_tag="VVR43_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU6149475.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1061..2398
                     /locus_tag="VVR43_001111"
     CDS             1061..2398
                     /locus_tag="VVR43_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU6149476.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIGVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2477..3361
                     /locus_tag="VVR43_001112"
     CDS             2477..3361
                     /locus_tag="VVR43_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6149477.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKVVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3361..4194
                     /locus_tag="VVR43_001113"
     CDS             3361..4194
                     /locus_tag="VVR43_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6149478.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4212..6305
                     /gene="nanB"
                     /locus_tag="VVR43_001114"
     CDS             4212..6305
                     /gene="nanB"
                     /locus_tag="VVR43_001114"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU6149479.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGMEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDACYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6318..7421
                     /locus_tag="VVR43_001115"
     CDS             6318..7421
                     /locus_tag="VVR43_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU6149480.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQNGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVVHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7595..8293
                     /locus_tag="VVR43_001116"
     CDS             7595..8293
                     /locus_tag="VVR43_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU6149481.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8312..9829
                     /locus_tag="VVR43_001117"
     CDS             8312..9829
                     /locus_tag="VVR43_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU6149482.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETIAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9954..11282
                     /locus_tag="VVR43_001118"
     CDS             9954..11282
                     /locus_tag="VVR43_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6149483.1"
                     /translation="MKFRKLACTVLASAAVLGLAACGNSGGSKDAGKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDVKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDDFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATGWIKDNLLNNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYDDKRMETISSWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11535..12401
                     /locus_tag="VVR43_001119"
     CDS             11535..12401
                     /locus_tag="VVR43_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6149484.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMIMGFITSFFNYSMTSFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNAIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAIMIAIVSF
                     VQFKVLGNDVEY"
     gene            12417..13256
                     /locus_tag="VVR43_001120"
     CDS             12417..13256
                     /locus_tag="VVR43_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6149485.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13528..13980
                     /locus_tag="VVR43_001121"
     CDS             13528..13980
                     /locus_tag="VVR43_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU6149486.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNRFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14077..14421
                     /locus_tag="VVR43_001122"
     CDS             14077..14421
                     /locus_tag="VVR43_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149487.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVTALIGRYIKLGTY
                     AVKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            14708..15352
                     /locus_tag="VVR43_001123"
     CDS             14708..15352
                     /locus_tag="VVR43_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU6149488.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15521..16438
                     /locus_tag="VVR43_001124"
     CDS             15521..16438
                     /locus_tag="VVR43_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU6149489.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTSSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTAAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEDDRPVVEAAAALIRETKERFL"
     gene            16456..17340
                     /locus_tag="VVR43_001125"
     CDS             16456..17340
                     /locus_tag="VVR43_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6149490.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFAI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDGKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVEYVAAAHGDPVDQWNGRRIFKEATEGNKFCMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAKH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17356..18207)
                     /locus_tag="VVR43_001126"
     CDS             complement(17356..18207)
                     /locus_tag="VVR43_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU6149491.1"
                     /translation="MDKPDIATVIDSHFEEMTDLEQEIARYFLQAETIKDDLSSQHVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHEAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEVQLERIAQLIEEAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGTTPSILDSLLDAKEMGAKTVLFSSVPNKDSQAYTET
                     VLVATHSQSSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18383..20440
                     /locus_tag="VVR43_001127"
     CDS             18383..20440
                     /locus_tag="VVR43_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEU6149492.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKVTTSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKEIA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVPTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEVDTYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELGNGGAKYSEGVYAVALNPKTGAVLSMSGLKHDLNTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQPIVFQGSAPIYSWYKLAYGSFPITAVEALEYSSN
                     AYMVQTALGIMGQTYQPNMFVGTSNLETAMGKLRATFGEYGLGAATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANDGVRVAPRIVEGIYGNNDKGGLGE
                     LIQAIDTKEINKVNISESDMAILHQGFYQVSHGTSPLTTGRAFSDGATVSISGKTGTG
                     ESYVAGGQEANNTNAVAYAPTENPQIAVAVVFPHNTNLTKNVGPAIARDIINLYNQHH
                     PMN"
     gene            20451..21047
                     /gene="recR"
                     /locus_tag="VVR43_001128"
     CDS             20451..21047
                     /gene="recR"
                     /locus_tag="VVR43_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU6149493.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMPDDDVNEFA
                     KNLLAAKRELTYCSICGRLTDEDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21223..22266
                     /locus_tag="VVR43_001129"
     CDS             21223..22266
                     /locus_tag="VVR43_001129"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU6149494.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDSIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWENMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22350..23723
                     /locus_tag="VVR43_001130"
     CDS             22350..23723
                     /locus_tag="VVR43_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU6149495.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENECK"
     gene            23710..24321
                     /locus_tag="VVR43_001131"
     CDS             23710..24321
                     /locus_tag="VVR43_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6149496.1"
                     /translation="MNASDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDADEVAELLKPTSAYATPLMDVRAWIVEDEKICLVRGQGENDWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            24412..25116
                     /locus_tag="VVR43_001132"
     CDS             24412..25116
                     /locus_tag="VVR43_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU6149497.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYRENK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25335..26708
                     /gene="ftsA"
                     /locus_tag="VVR43_001133"
     CDS             25335..26708
                     /gene="ftsA"
                     /locus_tag="VVR43_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU6149498.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26725..27984
                     /gene="ftsZ"
                     /locus_tag="VVR43_001134"
     CDS             26725..27984
                     /gene="ftsZ"
                     /locus_tag="VVR43_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU6149499.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27989..28660
                     /locus_tag="VVR43_001135"
     CDS             27989..28660
                     /locus_tag="VVR43_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU6149500.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28670..29209
                     /locus_tag="VVR43_001136"
     CDS             28670..29209
                     /locus_tag="VVR43_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU6149501.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29209..29472
                     /locus_tag="VVR43_001137"
     CDS             29209..29472
                     /locus_tag="VVR43_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU6149502.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29469..30254
                     /locus_tag="VVR43_001138"
     CDS             29469..30254
                     /locus_tag="VVR43_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU6149503.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30263..31051
                     /gene="divIVA"
                     /locus_tag="VVR43_001139"
     CDS             30263..31051
                     /gene="divIVA"
                     /locus_tag="VVR43_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU6149504.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31399..34191
                     /locus_tag="VVR43_001140"
     CDS             31399..34191
                     /locus_tag="VVR43_001140"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU6149505.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10640 a         6073 c         7490 g        10297 t
ORIGIN      
        1 aaaaaaaagt atactctaat tgaaaacggt aacaaaacta atttagagaa tgaaatatag
       61 agtatttctc tcttaaaagt ttttggtgaa acgagatgta gaaaggagat ttagccaaag
      121 agtctattag tgctagaata atagattaga attattttag aaaaacgaag tgagcagctt
      181 ataaattcaa gtccccaaat agattcatac tagtatcttt tgcaaaaaat aaagggcgac
      241 ttccgtcatg aatatcaatt tcatctataa ggaaggtagc taattgaact aacttattta
      301 ttctgtttgt cgctagaaaa atcagacctc cttgtgaaga ttgaggagat actgaatgaa
      361 aatcaaagaa gaaactagca agctagtagc agattgccca aaacaccgcc ttgaggttgt
      421 agataagact gacctatata atccaaggtg aagcgactgt ggtttgaaga gattttcaaa
      481 gagtataggc tagagagtag tgtttttatg tccttctagt agaaaatgct agacagaaga
      541 atggggaact tggataggaa aaatagattg agaaaggagg ttagaagaga tgattattac
      601 aaaaattagc cgtttaggaa cttatgtggg agtaaatcca cattttgcaa cattaataga
      661 ttttctagaa aaaacaggac tagaaaattt aacagaaggt tcgattgcta tcgatggtaa
      721 tcgattgttt gggaattgct ttacttatct agcagatggt caagcagggg ctttctttga
      781 aacacaccaa aaatatttgg atattcattt agttttggaa aacgaagaag ccatggctgt
      841 tacatcgccg gaaaatgtaa gcgttaccca agaatatgat gaagagaaag atattgaatt
      901 atacacaggg aaagtggaac agttggttca tttgagagct ggcgaatgcc tcatcacttt
      961 tccagaagat ttacatcaac ccaaggttcg tataaatgat gaacctgtga aaaaagttgt
     1021 ctttaaagtt gcgatttctt aatgtagaaa gagaagaacg atgaaaaaaa tgagaaagtt
     1081 tttatgtcta gctggaattg cgctagcggc tgttgccttg gtagcttgtt caggaaaaaa
     1141 agaagctaca actagtactg aaccaccaac agaattatct ggtgagatta caatgtggca
     1201 ctcctttact caaggacccc gtttagaaag tattcaaaaa tcagcagatg ctttcatgca
     1261 aaagcatcca aaaacgaaaa tcaagattga aacattttct tggaatgact tctatactaa
     1321 atggactaca ggtttagcaa atggaaatgt gccagatatc agtacagctc ttcctaacca
     1381 agtaatggaa atggtcaact cagatgcttt ggttccgcta aatgattcta tcaagcgtat
     1441 tggacaagat aaatttaacg aaactgcctt aaatgaagca aaaatcggag atgattacta
     1501 ctctgttcct ctttattcac atgcacaagt catgtgggtt agaacagatt tgttaaaaga
     1561 acataatatt ggggttccta aaacttggga tcaactctat gaagcttcta aaaaattgaa
     1621 agaagctgga gtttatggct tgtctgttcc gtttggaaca aatgacttaa tggcaacacg
     1681 tttcttgaac ttctacgtac gtagtggtgg aggaagcctc ttaacaaaag atcttaaagc
     1741 agacttgaca agccaacttg ctcaagatgg tattaaatac tgggttaaat tgtataaaga
     1801 aatctcacct caagattctt tgaattttaa tgtccttcaa caagctacct tgttctatca
     1861 aggaaaaaca gcatttgact ttaactctgg cttccatatc ggaggaatta atgccaacag
     1921 tcctcaattg attgattcga ttgatgctta tcctattcca aaaatcaaag agtctgataa
     1981 agaccaagga attgaaacct caaacattcc aatggttgtt tggaaaaatt caaaacatcc
     2041 agaagttgct aaagcattct tagaagcact ttataatgaa gaagactacg ttaaattcct
     2101 tgattcaact ccagtaggta tgttgccaac tattaagggg attagcgatt ctgcagccta
     2161 taaagaaaat gaaactcgta agaagtttaa acatgctgaa gaagtaatta ctgaagctgt
     2221 taaaaaaggt actgctattg gttatgaaaa tggaccaagt gtacaagctg gtatgttgac
     2281 taaccaacac attattgaac aaatgttcca agatatcatt acaaatggaa cagatcctat
     2341 gaaagcagca aaagaagcag aaaaacaatt aaacgattta tttgaggctg ttcagtagat
     2401 gtaaaagact agaaaatagg tgggctagtg agctgaaaag ctctagccca atcttgtaaa
     2461 agaagggaga aggagaatgg ttaaagaacg taatttaact cgctggatat ttgttttgcc
     2521 agctatgatt atcgtaggat tactctttgt ttatccgttt ttctcgagta ttttttatag
     2581 ctttaccaat aagcatttga ttatgcctaa ttataaattt gttggtttgg ctaactataa
     2641 agttgtgcta tcagatccca acttctttaa tgcgttcttt aattcaatta agtggaccgt
     2701 tttctcatta gttggtcaag ttttagtagg gtttgtattg gctttagctc ttcacagagt
     2761 acgccacttc aagaaattat ataggacctt attgattgtt ccttgggcat ttcctaccat
     2821 cgtcattgcc ttttcttggc agtggattct aaacggggtt tatggctact tacctaatct
     2881 aatcgtaaaa ttaggtttaa tggaacatac acctgcattt ttgacagata gtacatgggc
     2941 attcctatgt ttggtgttta tcaacatttg gtttggagca ccaatgatta tggttaatgt
     3001 gctttcagct ttgcaaacag taccagaaga acaatttgag gctgctaaga tagatggtgc
     3061 ttcaagttgg caggtgttca agtttatcgt ctttccacat attaaagtgg ttgtaggact
     3121 tctagttgtt ttgagaactg tatggatctt taataacttt gacattatct acctcattac
     3181 tggtggtgga ccagccaatg ctacaacgac gcttccaatt tttgcttaca acctgggctg
     3241 gggaactaaa ttgttgggtc gtgcttcagc agttacagta ttgctcttta tcttcttggt
     3301 ggcgatttgc tttatctact ttgctatcat cagtaagtgg gaaaaggagg gtagaaaata
     3361 atgaagaaga aatccagtat ttatttagat attctctcac atgtactttt agttggtgcg
     3421 accatcgttg caattttccc attggtatgg attatcatat cttctgtcaa agggaaaggg
     3481 gaattaactc agtatccaac acgattttgg cctgaacagt ttacattaga ttatttcact
     3541 catgttatca acgatttgca cttcattgat aacattcgaa acagtttaat cattgccttg
     3601 gctacaaccc tcattgcgat tattatttct gctatggcag cctatggtat tgttcgattc
     3661 tttcctaaat tgggagcaat catgtcgaga ctactcgtca ttacctacat tttcccacca
     3721 attttgttag caattcccta ttcaattgcc attgctaaag ttgggttaac aaatagttta
     3781 tttggcttga tgatggttta tctatctttt agtgttccat atgcagtttg gctcttagtt
     3841 ggatttttcc aaacagttcc aattggaatt gaagaagcgg ctagaattga tggtgcaaat
     3901 aaatttgtta cgttttataa agttgtgcta ccgattgtag caccaggtat tgtagcaaca
     3961 gctatttata catttatcaa tgcttggaat gaattcctgt atgccttgat tttgattaac
     4021 aatacaggaa agatgacagt agcagtagcc cttcgttcac ttaatggttc agaaatacta
     4081 gactggggag atatgatggc agcgtctgtt attgtagttc ttccatcaat tattttcttc
     4141 tctatcatcc aaaataagat tgcaagtgga ttatcagaag gatctgtgaa gtagacgaaa
     4201 gaaggaaaaa aatgaataaa agaggtcttt attcaaaact aggaatttct gttgtaggca
     4261 ttagtctttt aatgggagtc cccactttga ttcatgcgaa tgaattaaac tatggtcaac
     4321 tgtccatatc tcctattttt caaggaggct catatcaact gaacaataag agtatagata
     4381 tcagcccttt gttattagat aaattgtctg gagagagtca gacagtagta atgaaattta
     4441 aagcagatga accaaactct cttcaagctt tgtttggcct atctaatagt aaagcaggct
     4501 ttaaaaataa ttacttttca attttcatga gagattctgg tgagataggt gtagaaataa
     4561 gagacgccca aaagggaata aattatttat tttccagacc agcttcatta tggggaaaac
     4621 ataaaggaca ggcagttgaa aatacactag tatttgtatc tgattctaaa gataaaacat
     4681 acacaatgta tgttaatgga atggaagtgt tctctgaaac agttgataca tttttgccaa
     4741 tttcaaatat aaatggtata gataaggcaa cactaggagc tgttaatcgt gaaggtaagg
     4801 aacattacct cgcaaaagga agtattggtg aaatcagtct atttaacaaa gcaattagtg
     4861 atcaggaagt ttcaactatt cccttgtcaa atccatttca gttaattttc caatcaggag
     4921 attctactca agctaactat tttagaatac cgacactata tacattaagt agtggaagag
     4981 ttctatcaag tattgatgca tgttatggtg ggactcatga ttctaaaagt aagattaata
     5041 ttgccacttc ttatagtgat gataatggga aaacgtggag tgagccaatt tttgctatga
     5101 agtttaatga ctatgaggag cagttagttt actggccacg agataataaa ttaaagaata
     5161 gtcaaattag tggaagtgct tcattcatag attcatccat tgttgaagat aaaaaatctg
     5221 ggaaaacgat attactagct gatgttatgc ctgcgggtat tggaaataat aatgcaaata
     5281 aagccgactc aggttttaaa gaaataaatg gtcattatta tttaaaacta aagaagaatg
     5341 gagataacga tttccgttat acagttagag aaaatggtgt cgtttatgat gaaacaacta
     5401 ataaacctac aaattatact ataaatgata agtatgaagt tttggaggga ggaaagtctt
     5461 taacagtcga acaatattcg gttgattttg atagtggctc tttaagagaa aaacataatg
     5521 gaaaacaggt ccctatgaat gttttctaca aagattcgtt atttaaagtg actcctacta
     5581 attatatagc aatgacaact agtcagaata gaggagagag ttgggaacaa tttaagttgt
     5641 tgcctccgtt cttaggagaa aaacataatg gaacttactt atgtcccgga caaggtttag
     5701 cattaaaatc aagtaacaga ttgatttttg caacatatac tagtggagaa ctaacctatc
     5761 tcatttctga tgatagtggt caaacatgga agaaatcctc agcttcaatt ccgtttaaaa
     5821 atgcaacagc agaagcacaa atggttgaac tgagagatgg tgtgattaga acattcttta
     5881 gaaccactac aggtaagata gcttatatga ctagtagaga ttctggagaa acatggtcgg
     5941 aagtttcgta tattgatgga atccaacaaa cttcatatgg cacacaagta tctgcaatta
     6001 aatactctca attaattgat ggaaaagaag cagtcatttt gagtacacca aattctagaa
     6061 gtggccgtaa gggaggtcaa ttagttgtcg gtttagtcaa taaagaagat gatagtattg
     6121 attggaaata ccactatgat attgatttgc cttcgtatgg ttatgcctat tctgcgatta
     6181 cagaattgcc aaatcatcac ataggtgtac tgtttgaaaa atatgattcg tggtcgagaa
     6241 atgaattgca tttaagcaat gtagttcagt atatagattt ggaaattaat gatttaacaa
     6301 aataaaggag aaaaaacatg gttaaatacg gtgttgttgg agcagggtat tttggagctg
     6361 aattggctcg ctatatgcaa aagaatgatg gagcagagat tactcttctc tatgatccag
     6421 ataatgcaga ggcgattgca gaagaattgg gagcaaaagt agcaagttcc ttagatgagt
     6481 tggtttctag cgatgaagta gattgtgtta tcgtcgcaac tccaaataat cttcataagg
     6541 aaccggttat taaggctgca cagaatggta aaaatgtttt ctgtgaaaaa ccaattgcgc
     6601 tttcttatca agattgtcgc gagatggtag atgcatgtaa agaaaacaat gtaaccttta
     6661 tggcaggaca tattatgaat ttctttaatg gtgttcatca tgcaaaagaa ctcattaatc
     6721 aaggagttat cggagacgtt ctatattgtc atacagctcg taatggttgg gaagaacaac
     6781 aaccgtcagt atcatggaaa aaaattcgtg aaaaatcagg tggtcacttg tatcaccaca
     6841 tccatgaatt ggattgcgtt caattcctta tggggggcat gcctgaaact gtaaccatga
     6901 caggtggaaa tgtggtccat gaaggtgaac atttcggtga tgaagatgat atgatttttg
     6961 tcaatatgga attttctaat aagcgttttg ccttgttaga atggggttca gcttatcgtt
     7021 ggggtgaaca ttatgtctta atccaaggaa gcaaaggtgc catccgctta gacttattca
     7081 actgtaaagg aactcttaag ctagatgggc aagaaagcta tttcttgatt cacgaatcgc
     7141 aagaagaaga tgatgatcgg actcgtatct atcatagtac agagatggat ggagcaattg
     7201 cttatggtaa accaggtaaa cgtactccat tatggctatc atctgtcatt gataaagaaa
     7261 tgcgctatct gcatgagatt atggaaggag ctccagtatc agaagaattt gcaaaacttt
     7321 tgacaggtga agctgcccta gaagcaattg ctactgcaga tgcttgtacc cagtctatgt
     7381 ttgaagatcg caaagtaaaa ttgtcagaaa ttgtaaaata aattttggta ttctcctatt
     7441 tataggtcga cttgctcctc tgaaagtact tttagaggag ctgtttgact ttgctagttt
     7501 ttgaaactga aatctattat actacaaact attgaaagcg ttttaatttt aaggtataat
     7561 aatctcatag aaataaagaa aaggaggaaa gaggatgcca cagattagca aagaagcctt
     7621 gattgagcaa atcaaagatg gaatcatcgt ttcttgtcag gctcttcctc atgaaccgct
     7681 ttatacagaa gcgggagggg tgattccctt gctggtcaaa gcggctgagc aaggtggggc
     7741 agtcggtatc cgagcaaaca gtgttcgcga tatcaaggaa attaaggaag tcactaaact
     7801 tccaatcatt gggattatca aacgtgatta tccacctcag gaacccttca tcacggctac
     7861 tatgaaagaa gttgatgaat tggcagaact ggacatcgag gtgattgctc tggattgtac
     7921 caagcgtgaa cgctacgatg gtttggaaat tcaagagttc attcgtcagg ttaaggagaa
     7981 atatcctaat cagcttttga tggctgatac tagtatcttc gaagaagggc tagcagctgt
     8041 agaagcagga attgactttg tcggaacaac cttatcaggc tacacatcct acagtccaaa
     8101 agtagacggt ccagattttg aattgattaa gaaactctgt gatgccggtg tagatgtcat
     8161 tgcagaagga aaaattcata caccagaaca agccaaacaa atccttgaat atggagtgcg
     8221 aggcatcgtt gttggtggcg ctattactag accaaaagag attacagaac gcttcgttgc
     8281 tagtcttaaa taagatgtga gggggagttt tatgtttaaa gttttacaaa aagttggaaa
     8341 agcttttatg ttacctatag ctatacttcc tgcagcaggt ctacttttgg ggattggtgg
     8401 tgcactttca aacccaacca cgatagcaac ttatccaata ctagacaata gtatttttca
     8461 atcgatattc caagtaatga gctctgcagg agaggttgta ttcagtaatt tgtcactact
     8521 tctctgtgtg ggattatgta ttggcttagc gaaacgagat aaaggaaccg ctgcgttagc
     8581 aggagtaact ggttacttag ttatgactgc aacgatcaaa gctttggtaa aactttttat
     8641 ggcagaagga tctgcaattg atactggagt tattggagca ttagttgtcg gaatagttgc
     8701 cgtatatttg cacaaccgat ataacaatat tcaattacct tccgctttag gattctttgg
     8761 aggttcacgc ttcgttccta ttgttacatc gttctcttct atcttgattg gctttgtctt
     8821 ctttgttatt tggccacctt tccaacaact tcttgtttct acaggtggat atatttctca
     8881 ggcgggtcca attggaactt ttctatatgg atttttaatg agactttctg gagcagtagg
     8941 cttacatcat ataatttacc ctatgttttg gtatactgaa cttggtggtg ttgaaactat
     9001 tgcaggacaa acagtggttg gagctcaaaa aatatttttt gctcaattag ccgatccggc
     9061 ccattctgga ttatttacag aaggaacaag gttttttgca ggtcgtttct caacaatgat
     9121 gttcggttta ccggctgcct gtttagcgat gtaccatagt gttcctaaaa atcgtcgtaa
     9181 aaaatacgcg ggtttgtttt ttggagttgc tttaacatct tttattaccg gtattacaga
     9241 accaattgaa tttatgtttc tattcgtcag tccggttcta tatgttgttc acgcattcct
     9301 tgatggtgtt agcttcttta ttgcagacgt cttaaatatt tcaataggaa acacattttc
     9361 aggaggtgta atcgatttca cattatttgg aattttgcag gggaacgcta agacgaattg
     9421 ggttcttcag attccaattg gacttatttg gagtgttttg tattatatta tttttagatg
     9481 gttcattact caattcaacg ttctaacgcc aggacgagga gaagaagtag attctaaaga
     9541 aatttctgaa tccgcagatt caacttcaaa tactgcagat tatttaaaac aggatagcct
     9601 acaaattatc agagccttgg gtggatcaaa taatatagaa gatgtagatg cttgtgtgac
     9661 acgtttacgt gtagctgtaa aagaagttaa tcaagttgat aaagcacttt taaaacaaat
     9721 tggtgcagtt gatgtcttag aagtgaaggg tggcattcaa gcaatctatg gagcaaaagc
     9781 aatcttatat aaaaatagta ttaatgaaat tttaggtgta gatgattaag tacttactga
     9841 cttaataaaa aacagaggag agtgatggat gagtaggatg aaatgaaatc gcatataaga
     9901 aataaagaac tcattatcca agttggatac gcttattaca taggagaata cagatgaaat
     9961 ttagaaaatt agcttgtaca gtacttgcga gtgctgcggt tcttggtctt gctgcttgtg
    10021 gcaattctgg cggaagtaaa gatgctggca aatcaggtgg tgacggtgcc aaaacagaaa
    10081 tcacttggtg ggcattccca gtatttaccc aagaaaaaac tggtgacggt gttggaactt
    10141 atgaaaaatc aatcatcgaa gcgtttgaaa aagccaatcc agatgtaaaa gtgaaattgg
    10201 aaaccatcga cttcaagtca ggtcctgaaa aaatcacaac agctatcgaa gctggaacag
    10261 ctccagacgt actctttgat gcaccaggac gtatcatcca atacggtaaa aacggtaaat
    10321 tggctgagtt gaacgacctc ttcacagatg actttgttaa agatgtcaac aatgaaaaca
    10381 tcgtacaagc aagtaaagct ggagacaagg cttacatgta tccaattagt tctgccccat
    10441 tctacatggc aatgaacaag aaaatgttag aagatgctgg agttgcaaac cttgtaaaag
    10501 aaggttggac aactgatgat tttgaaaaag tattgaaagc acttaaagac aagggttaca
    10561 caccaggttc attgttcagt tctggtcaag ggggagacca aggaacacgt gcctttatct
    10621 ctaaccttta tagcggttct gtaacagatg aaaaagttag caaatataca actgatgatc
    10681 ctaaattcgt caaaggtctt gaaaaagcaa ctggctggat taaagacaat ttgctcaata
    10741 atggttcaca atttgacggt ggggcagata tccaaaactt tgccaacggt caaacatctt
    10801 acacaatcct ttgggcacca gctcaaaatg gtatccaagc taaactttta gaagcaagta
    10861 aggtagaagt ggtagaagta ccattcccat cagacgaagg taaaccagct cttgaatacc
    10921 ttgtaaacgg atttgcagta ttcaacaaca aagacgacaa gaaagttgca gcatctaaga
    10981 aattcatcca atttatcgca gatgacaaag agtggggtcc aaaagacgta gttcgtacag
    11041 gtgccttccc agttcgtaca tcatttggca aactttatga tgacaaacgt atggaaacaa
    11101 tcagcagctg gactcaatac tactcaccat actacaacac tattgatgga tttgctgaaa
    11161 tgagaacact ttggttccca atgttgcaat ctgtatcaaa tggtgacgaa aaaccagcgg
    11221 acgctttgaa agccttcact gaaaaagcga acgaaacaat caaaaaagct atgaaacaat
    11281 agtccttagt tattctataa aaagtagttt tttaaagaac ctaagagtgt ataccccctt
    11341 ttccctctac acagatagtg taagaaaagg ggggcttttg tttaaaacgt aagaaattgt
    11401 cacgaaatta aaatgaagtt cttacataag tgaatcataa aaaatttcat tttgatttta
    11461 aaacagttca agaaagtcaa aaaattattc tatttgaaag agaggtgccg actgtgaaag
    11521 tcaataaaat ccgtatgcgg gaaacagtga tttcctatgc tttcctagca ccagtgttgt
    11581 tcttctttgt catctttgta ttggctccaa tgattatggg ctttattaca agtttcttta
    11641 actactctat gactagcttt gaatttgtgg gcttagataa ctatatccgt atgtttaaag
    11701 atcctgtctt tacaaaatct ttgattaaca cagttatttt ggttattgga tctgtgccag
    11761 ttgttgttct attctcactc tttgtagcgt cacagaccta ccatcaaaat gctatcgcta
    11821 gatcattcta tcgtttcgta ttcttccttc cagttgttac aggtagtgtt gccgtaacag
    11881 ttgtatggaa atggatttat gacccactat cagggattct aaactttgtc cttaagtcca
    11941 gccacatcat cagccaaaac atttcttggt tgggagataa aaactgggca ttgatggcga
    12001 ttatgattat tctcttgacc acttcagttg gtcagcccat catcctttat atcgctgcca
    12061 tggggaatat tgacaattca ctggttgaag cggcgcgtgt tgatggtgca actgagtttc
    12121 aagttttttg gaagattaaa tggccaagcc ttcttccaac aactctttat attgcaatca
    12181 tcacaacaat taactcattc cagtgttttg ccttgattca gcttttgaca tctggtggtc
    12241 caaactactc aacaagtacc ttgatgtact acctttacga aaaagccttc caattgacag
    12301 aatacggcta tgccaacaca attggtgtct tcttggcaat catgattgct atcgtaagct
    12361 ttgttcaatt taaagtactt ggaaacgacg tagaatacta aagaaaggag acagctatgc
    12421 aatctacaga aaaaaaacca ttaacagcct ttactgttat ttcaacaatc attttgctct
    12481 tgttgactgt gctgttcatc tttccattct actggatttt gacaggggca ttcaaatcac
    12541 aacctgatac aattgttatt cctcctcagt ggttccctaa aatgccaacc atggaaaact
    12601 tccaacaact catggtgcag aaccctgcct tgcaatggat gtggaactca gtatttatct
    12661 cattggtaac catgttctta gtctgtgcaa cctcatctct agcaggttat gtattggcta
    12721 aaaaacgttt ctatggtcaa cgcattctat ttgctatctt tatcgctgct atggcgcttc
    12781 caaaacaagt tgtccttgta ccattggtac gtatcgtcaa cttcatggga atccacgata
    12841 ctctctgggc agttatcttg cctttgattg gatggccatt cggtgtcttc ctcatgaaac
    12901 agttcagtga aaatatccct acagagttgc ttgaatcagc taaaatcgac ggttgtggtg
    12961 agattcgtac cttctggagt gtagccttcc cgattgtgaa accagggttt gcagcccttg
    13021 caatctttac cttcatcaat acttggaatg actacttcat gcaattggta atgttgactt
    13081 cacgtaacaa tttgaccatc tcacttgggg ttgcgaccat gcaggctgaa atggcaacca
    13141 actatggttt gattatggca ggagctgccc ttgctgctgt tccaatcgtc acagtcttcc
    13201 tagtcttcca aaaatccttc acacagggta ttactatggg agcggtcaaa ggataatact
    13261 ctgagaaaat ctcttcaaac tacgtcagcg tcaccttgcc atacttaagt attgcctgcg
    13321 gttagcttcc tagtttgttc ttcaattttc attgagtata ggaaaatcaa tctatcaaga
    13381 tacagaagta tattttatag atttagagaa tatagaggtt ataagtgtct acaaaatgga
    13441 gggtatgcag ttactttatg aagttttgtc agacacttat aaacttaaga atggttttag
    13501 ttaactatca gaaacgaagg aaagagtatg atttttgacg atttgaaaaa catcaccttt
    13561 tacaaaggga ttcatcccaa tttagacaag gctatcgact atctctacca acatcgtaaa
    13621 gattcattcg aattaggaaa gtatgagatt gatggagata aagtctttct agttgttcag
    13681 gaaaatgtcc tcaatcaagt tgagaataat cgatttgaac accataagaa ctatgcagat
    13741 ttgcatttgc tgatagaagg gcatgaatat tcgagctacg gttcacgtat caaagacgag
    13801 gcagtagcat tcgacgaagc gagtgacatt ggctttgttc attgtcatga acactaccca
    13861 ctcttgttgg gttatcacaa ttttgcgatt ttcttcccag gtgagccaca tcagccaaat
    13921 ggttatgcag gcatggaaga aaaggttcga aaatatctct ttaaaatttt gattgattaa
    13981 aaataggatg aattgttttt ttgtaaagct ttgataatac tctaccatga aattgatctt
    14041 tgtgaggtag agaaatgaga ataaaatatt taaaaattgg tatcttctaa gtatgctgca
    14101 agagctagtt tcttagatgg acaggggatt acagttgatg agatggcttg gataattagg
    14161 ggcattgtga ctgcattgat tggtagatac ataaaattag gtacttatgc agttaagtat
    14221 ggtattagta tggcgcgctc gatcttaagt agggcagctg caactgcggc agcaagagta
    14281 ggattattga ctaagatttt tggatggatt ttacgaatag ctgtgctcgc agctgatgta
    14341 tatggtaatt ttgccaacaa tattgctgta gcttgggatg cacatgataa aatccctaac
    14401 aatggtcgta taaactttta aaatgcgaga atgaaagcac tttgtatttt tttattgtat
    14461 atgttagctt ggacagtgct tgcaatgata atccgtggag ggctagatgg atttgatgaa
    14521 cacacttggc gtactatttt aattgcttcg ctgtccggga tatatataga ttatatgtcc
    14581 atagataaaa gtagaaaaaa gtccaaaaga aaaaagaaaa aatagatttg ttcatggtag
    14641 ggacttatga aagctttact gacaaaaaag aaaacagttt acaaagaaaa atgatggagg
    14701 agcaaacatg gcacaaaaag gagtaagcct tatcaaggca gcatttgata cagataactt
    14761 tctcatgcgt tttagtgaga aagtcttgga catcgtgaca gccaatcttc tttttgtcgt
    14821 ctcttgtttg cccatcgtga cgattggagt ggctaaaatc agcctctacg agaccatgtt
    14881 cgaagttaag aagagcagac gggtgcctgt ttttaaaatc tatctaagat ctttcaagca
    14941 aaatctgaaa ctaggtcttc agctgggttt aatggagtta ggaattgtgt ttcttaccct
    15001 ttcagatctc tatcttttct ggggtcaaac agctctgccc ttccaattgc tgaaagccat
    15061 ttgtctaggc attctgattt tccttacgat tgtgatgttg gctagctatc caatcgcggc
    15121 acgttatgat ttaacttgga aagaagtgtt acaaaaaggg cttatcttgg ctagttttaa
    15181 ctttccttgg ttcttcctca tgttagccat tcttgtcctc attgtgatgg ttctttatct
    15241 gtccgccttc agtctactct taggtggctc agtcttccta ctttttgggt ttggactatt
    15301 ggtctttatc cagactggat tgatggagaa aattttcgca aaataccaat aggagcctta
    15361 tttctgaaac tactttcaaa ggctccaaac gctattctat aagcgagaaa ctaaaatcta
    15421 agtgtctata agatattgaa agccttttcg gtaaagtgta tactaaagaa gtaaagaaaa
    15481 atctgcttta gcagaaaata aaaataatag gagaaaatct atgtcagatt tgaaaaaata
    15541 cgaaggtgtc attccagcct tctacgcatg ttatgatgag caaggagaag taagtccaga
    15601 gcgtacgcgt gccttggttc aatacttcat tgataaaggt gttcaaggtc tttatgtcaa
    15661 tggttcttct ggtgaatgta tctaccaaag cgttgaagat cgcaagttga ttttggaaga
    15721 agtcatggcg gtagccaaag gtaaattgac cattattgcc catgttgctt gcaataatac
    15781 taaagatagt atggaacttg ctcgccatgc tgaaagcttg ggagtagatg ctattgcaac
    15841 gattccacca atttacttcc gcttgccaga atactcagtt gccaaatact ggaacgatat
    15901 tagttctgca gctccaaaca cagactacgt gatttacaac attcctcaat tggcaggggt
    15961 tgctttgact tcaagccttt acacagaaat gttgaaaaat cctcgtgtta tcggtgttaa
    16021 gaactcttca atgccagttc aagatatcca aacctttgtc agccttggcg gggaagacca
    16081 tattgtcttt aacggtccag atgaacagtt cctaggtggc cgcctcatgg gtgctaaggc
    16141 tggtatcggt ggtacttatg gtgctatgcc agaactcttc ttgaaactca atcagttgat
    16201 tgcggataaa gatttagaaa cagcgcgtga attgcagtat gctatcaacg caatcattgg
    16261 taaactcact gctgcacatg gaaatatgta cggtgtcatc aaagaagttt tgaagatcaa
    16321 tgaaggcttg aatattggtt ctgttcgttc accattgaca ccagtgactg aagacgatcg
    16381 tccagttgta gaagcggctg cagccttgat tcgtgaaacc aaggagcgct tcctctaatc
    16441 taaaaggagg tatttatgac atactacgtt gcaattgata tcggtggaac taacatcaag
    16501 tatggtttgg ttgatcaaga ggggcaactt cttgaatcac atgaaatgcc aacagaggcg
    16561 cataagggtg gacctcatat cttacaaaag accaaagata tcgtagctag ttatttagaa
    16621 aaaggcccag tagcaggtgt tgccatatct tctgctggga tggtggatcc ggataagggt
    16681 gagattttct atgctgggcc gcaaatccct aactacgcag gcacccagtt caaaaaggaa
    16741 atcgaagaaa gctttgctat tccttgtgag attgaaaatg atgtcaactg tgcaggtctg
    16801 gctgaggcag tatctggttc aggtaaggga gcaagtgtca ccctttgctt gaccattgga
    16861 acaggtattg gtggttgttt gattatggat gggaaagtct tccatggatt tagcaattca
    16921 gcctgtgaag ttggttatat gcatatgcag gatggagcgt ttcaagattt ggcttctaca
    16981 acagccttgg tggagtatgt agcagcagct catggagatc cagttgacca gtggaatggt
    17041 cgtcgtatct ttaaggaagc tacggaaggc aataaattct gcatggaagg tattgaccgc
    17101 atggtagact atctaggaaa aggtctggca aatatttgct acgttgccaa tccagaagtg
    17161 gtcattctcg gtggcggtat catgggacaa gaggcgattc tcaaaccgaa aatccgcaca
    17221 gccttgaaag aggctttggt accaagtttg gctgagaaaa caagattaga attcgccaag
    17281 caccaaaata ccgcaggcat gttgggtgct tattatcatt ttaaaacaaa acaatcctag
    17341 tttggcttag ccaaactagg attttctgac acgtttttgt ctacgatagc cgttgagttt
    17401 tttattttcc cagtagctat taaagatttt ctccttactt tcacgattga tttccaaaaa
    17461 gtaggcgtaa atcaaatcga taaagaagag cataggaagt tgagcggata tacgttggat
    17521 gtaagaagac tggctgtggg tggctacaag aacagtctct gtgtaggcct gactatcttt
    17581 attgggaaca cttgaaaaaa gtacagtctt tgcgcccatc tccttagcgt ctaatagact
    17641 atctaaaata gaaggagttg tgccagaaag tgagaaaccg agtacgagac aattttcatc
    17701 cataatactg gttgtccaag caaagccgtc ttggtctgtc aaagcttcgc agacaacacc
    17761 cagacgcatg aagcgcaatt tcatttcacg agcaacaaga ccagaactcc ctgttccgaa
    17821 gaagtagata cgctcagcct cttcgattag ctgggcaatt cgttctagtt ggacttcgtc
    17881 aatcaagtct tgtgtttgtt ccctcatatt gctataactt ctgaggactc gtttggtcag
    17941 tggactgtgc ttggagactt ggttggcttg attttctgct tcatgttggt attggaaaat
    18001 aaattctcgg tagccagtaa agccacactt tttagcaaag cgggtcaaag cagcctgaga
    18061 gatatgtaat ttttgagtga catgttggga agataaatca tctttaatcg tttcagcttg
    18121 caaaaaatag cgagcgattt cttgctctag gtctgtcatt tcttcaaagt gtgaatcaat
    18181 gacagttgcg atatctggtt tgtccatagg gaaggctcct ttaaatgagt cgtgttggaa
    18241 aaagactaga ttattgaact tttacattca ttataacata taatataggg atgaataaat
    18301 aaaaacgaaa aaaagcatct ttcttttcca taattttctg ctcaaattgt ggtacaatta
    18361 agagtaagat tttaagttag aaatgagact gatttgtatg agaaaattta acagccattc
    18421 gattccgatt cggcttaatt tattgttttc aatcgtcatt ttactcttta tgaccattat
    18481 tggtcgtttg ttgtatatgc aggttttgaa caaggatttt tacgaaaaaa agctagcctc
    18541 agctagtcag accaaggtca caaccagttc tgctcgtggg gaaatctatg atgctagtgg
    18601 aaaacctttg gtagaaaata cgttaaagca ggttgtttcc tttacgcgta gcaataaaat
    18661 gacggctaca gacttaaaag aaatagctaa aaagttactg acttatgtga gcatcagttc
    18721 gccaaatttg acagaacgcc agctggctga ttactatttg gctgatcctg aaatctataa
    18781 aaaaacagtg gaagctctcc caagtgagaa acgattggat tcagatggca atcgcctatc
    18841 cgaatcagaa ctgtataaca atgcggtcga tagtgtccca acaagtcaac taaactatac
    18901 agaggatgaa aagaaagaaa tctatctttt tagtcagtta aatgctgttg gaaactttgc
    18961 gacaggaacc attgcgacag atcctctaaa tgattctcag gtggctgtta ttgcctctat
    19021 ttcaaaggag atgcctggca ttagtatttc tacttcttgg gatagaaagg ttttagaaac
    19081 ctctctttct tctatagtag gtagtgtatc cagtgaaaaa gctggtctcc cagcggaaga
    19141 agtggatacc tatcttaaaa aaggttattc tctaaatgat cgtgttggaa cctcctattt
    19201 ggaaaagcaa tatgaagaga ccttacaagg gaaacgctcg gtaaaagaaa tccatctgga
    19261 taaatatggc aacatggaaa gtgtggatac aattgaggaa ggtagtaagg gaaacaatat
    19321 caaactgacc attgatttgg cctttcaaga tagtgtggat gctttgttga aaagttattt
    19381 caattccgag ctaggaaatg ggggagccaa gtattctgag ggtgtttatg cagttgcttt
    19441 gaatcccaaa acaggtgcgg ttttgtctat gtcagggctc aaacatgacc tgaacacggg
    19501 agagttgact cctgattcct tgggaacggt aaccaatgtc tttgtcccag ggtcagtagt
    19561 taaggccgct accatcagct caggttggga aaatggtgtt ttatcaggaa accaaacctt
    19621 aacagatcag cctattgttt tccaaggttc agctccaatt tattcttggt ataaattggc
    19681 atatggatct tttcctatta cagctgtgga agccttggag tattcatcta atgcttacat
    19741 ggttcaaacc gctcttggaa tcatgggcca gacctatcaa ccaaatatgt ttgttggaac
    19801 cagcaatttg gaaacagcta tgggaaaact tcgtgcgacc tttggcgaat atggcttggg
    19861 ggctgcgacc ggaattgacc taccagatga atctactgga tttgttccca aagagtatag
    19921 ctttgctaat tacatcacca atgcctttgg gcagtttgat aactatacgc ccatgcagtt
    19981 ggctcagtat gtagcaacta ttgcaaatga tggtgttcgt gtggctcctc gtattgttga
    20041 aggtatttat ggaaataatg ataagggtgg ccttggggaa ttaatccaag caatagatac
    20101 caaggaaatc aacaaggtca atatttctga atcagatatg gcaatcttgc accaaggatt
    20161 ttaccaagta tcgcatggaa ctagtcccct tacgacagga cgggcgtttt cagatggcgc
    20221 cactgtttct atcagtggta agaccggtac aggtgaaagc tatgtagctg gtggtcaaga
    20281 agctaataat accaatgccg tggcctatgc tccaacagaa aatcctcaaa ttgcagttgc
    20341 agtagtcttt cctcataata ccaatttaac caaaaatgtt gggccagcaa ttgctcgcga
    20401 cattatcaat ttatataacc aacaccatcc aatgaattag aaaggaagcc atgctttatc
    20461 caacacctat tgctaagttg attgacagtt attccaaact tcctggtatt gggattaaga
    20521 cagcaactcg actggccttt tatactattg gaatgccgga tgacgacgtc aatgaatttg
    20581 caaaaaatct tcttgcagcc aagcgagaat tgacctattg ctctatttgt ggacgattaa
    20641 cagatgaaga cccgtgctct atctgtaccg atccgactcg tgaccagaca acgattttag
    20701 ttctcgaaga tagtcgcgat gtggcagcca tggagaatat ccaagaatac catggactct
    20761 atcatgtcct gcatggcctc atttctccta tgaatggtat cagtccagac gatatcaatc
    20821 tcaagagtct catgactcgt ctgatggata gtgaagtttc agaagtaatc gtagcaacca
    20881 atgctacagc agatggggaa gcgacttcca tgtatctttc ccgcttactc aagccagctg
    20941 ggattaaggt cactcgcctg gcacgaggcc tcgctgtggg agcagatatc gagtatgcgg
    21001 acgaagtgac actcttacga gcgattgaaa atcggacaga gttgtaagtg taggcaaatt
    21061 tacgaactcc attcatttat aaaaaatcaa agaggctgaa aatcgttcct atcggcctct
    21121 ttttgtatag tgtgatgagt agaatcaggt tcaagtttta aaaaaccaag caaatatgat
    21181 atactaaaga gcgagtattc tagtagaatt aggacaaata atatgaaaca aacgattatt
    21241 cttttatatg gtggacggag tgcggaacgc gaagtctctg tcctttcagc tgagagtgtc
    21301 atgcgtgcgg tcaattacga ccgtttcaca gtcaagactt tctttatcag tcagtcaggt
    21361 gactctatca aaacgcagga atttagtcat gctccggggc aagaagaccg tctcatgacc
    21421 aatgaaacca ttgattggga taagaaagtt gcaccaagtg ctatctacga agaaggtgca
    21481 gtggtctttc cagtccttca cgggccaatg ggagaagatg gctctgttca aggattcttg
    21541 gaagttttga aaatgcctta cgttggttgc aacattttgt catcaagtct tgccatggat
    21601 aaaatcacga ctaagcgtgt tctggaatct gctggtattg cccaagttcc ttatgtggct
    21661 atcgttgaag gcgatgatgt gactgctaaa atagctgaag tggaagaaaa attggcttat
    21721 ccagtcttca ctaagccgtc aaacatgggg tctagtgtcg gtatttctaa gtctgaaaac
    21781 caagaagaac tccgtcaagc cttaaaactt gccttccgat atgacagccg tgtcttggtt
    21841 gagcaaggag tgaatgcccg tgaaattgag gttggcctct tgggtaacta cgatgtcaag
    21901 agcacgctac ctggagaagt tgtcaaggac gttgcctttt atgactacga tgccaagtat
    21961 attgataaca aggttactat ggatattcct gccaaaatca gtgatgatgt ggtggctgtc
    22021 atgcgtcaaa atgcagaaac agccttccgt gccattggtg gccttggtct atctcgttgc
    22081 gatttcttct atacagataa gggagagatt tttctcaacg agctcaatac catgccaggt
    22141 ttcacccagt ggtctatgta cccactactt tgggaaaata tggggatcag ctacccagaa
    22201 ctaatcgagc gtttggttga ccttgccaag gaaagttttg acaagcgcga agcgcatttg
    22261 atataaaatg aaagagaggg tagaagccag aaccatcact gcaaggtgac tagagttctc
    22321 ggacttcagc cctttttaaa ggagtagaaa tgaaattaac aatccatgaa attgcccaag
    22381 ttgttggagc caaaaatgat atcagtatct ttgaggacac tcagttagaa aaagctgagt
    22441 ttgatagtcg tttgattgga actggagatt tatttgtgcc acttaaaggt gcgcgtgatg
    22501 gccatgactt tattgaaaca gcctttgaaa atggtgcagc agtaaccttg tctgagaaag
    22561 aggtctcaaa tcatccttac attttagtag atgatgtttt gacagccttt caatccctag
    22621 catcctacta tcttgaaaaa acgactgttg atgtctttgc tgttacaggt tcaaatggca
    22681 agacaacgac taaggatatg ttggcgcatt tactgtcaac aagatacaag acctacaaaa
    22741 cacaaggcaa ttacaataat gagattggcc ttccttacac agttcttcat atgcctgaag
    22801 gaacagaaaa gttggttttg gagatgggac aggatcactt gggagatatt catctcttgt
    22861 ctgaattggc tcgtccaaaa acagccatcg tgaccttggt tggagaagct catttggcct
    22921 ttttcaaaga tcgttctgag attgctaaag gaaaaatgca aattgcagac ggaatggctt
    22981 caggttcctt gcttttagcg ccggctgacc ctatcgtaga ggactatttg ccaattgata
    23041 aaaaggtggt tcgttttggt caaggagcag agctggaaat tactgacttg gttgagcgta
    23101 aggacagtct gacctttaag gctaatttct tggaacaagc ccttgatttg ccagtaactg
    23161 gcaagtacaa tgcgacaaat gctatgattg catcctatgt tgccttgcaa gaaggagttt
    23221 cagaggagca aattcgtttg gcattccaac atcttgaatt gacgcgtaac cgtaccgagt
    23281 ggaagaaagc agccaatgga gcagatatcc tgtcagatgt ttacaatgcc aatccaactg
    23341 ctatgaaact gattttagag actttctctg ccattccagc caatgaaggt ggcaagaaaa
    23401 ttgcagtgtt ggcggatatg aaggaactgg gtgaccagtc tgttcaactt cataatcaga
    23461 tgattttgag cctctcccca gatgtgcttg atatcgttat tttctatgga gaagatattg
    23521 ctcagttggc tcaattggcc agtcaaatgt ttccaatcgg ccacgtttac tacttcaaga
    23581 aaacagaaga ccaggatcaa tttgaagacc tagtcaagca ggttaaggaa agccttggag
    23641 cctatgacca aatcttgcta aaaggttcta actctatgaa tctagccaaa ttggtagaaa
    23701 gtttagaaaa tgaatgcaag tgattttgtc aagtatcttc aaagaatgat tgctcttaca
    23761 gatactggac taacctttac aaaggatccg tttgaccgtg agcgctacga agacttgcga
    23821 agtctgttat ctgaaatgtt gaatcaggta tcagaccttg atgcagacga agtggcagaa
    23881 ctcttgaaac cgacctccgc ttatgcgact cctttaatgg acgtccgtgc ttggatagtt
    23941 gaggatgaaa aaatttgtct ggttagggga caaggagaga atgattgggc tttgccaggt
    24001 ggctttggcg aggtcggtta ttcaccaact gaaaatattc tcaaggaaat tgaagaagaa
    24061 accggtttta aagccaaagt tgaacgacta ctagctgttt ttgataccaa tcgtttccaa
    24121 ctacagagca aacaatatgc aaagtttgtt tttgaatgta agcttctcga tggacaattt
    24181 caagaaaatc aagaaatcgc tgaccttcaa ttttttgcaa ttgaccaact gccgaattta
    24241 tctgaaaaac gcattaccaa ggagcaaata gagcttcttt ggcaggttta tcaaggtcat
    24301 agggggcaat atcttgacta agaagatgat tatcgtattt ctaaatccat ttttaacaac
    24361 tagcatggta taataatatg caggaaaatt ttgaattatg aggaagacta gatgaattta
    24421 tgggatattt tctttacgac tcaggcaacc gagccgccca aatttgacct tttttggtat
    24481 gttagcctat ttacgctctt agccttaacc ttttatacag cccatcgcta tcgtgaaaat
    24541 aaggtttacc aacgattttt ccaaatcttg cagactgttc agttaatcct tctttatggt
    24601 tggtactggg tcaatcatat gccactgtca gaaagcctac ccttttacca ttgccgtatg
    24661 gctatgtttg tggtactctt gcttcctggt caatccaaat ataaacaata ctttgcatta
    24721 ttgggaacat ttgggacatt agcagccttt gtttatccag tgccagatgc ttaccctttt
    24781 ccacatatca ccattctatc ctttatcttt ggtcatttag cactcttggg gaactctcta
    24841 gtttatctat tgagacagta taatgcgcga ttgctggatg tgaagggaat ttttctcatg
    24901 acctttgccc taaatgcctt gatttttgtg gtcaatttgg tgacaggtgg cgattacgga
    24961 tttttgacaa aaccgccatt ggttggggat cacggtctag tagctaatta tttacttgtt
    25021 tcaattgtgc tggtagctac tatcagtttg actaagaaaa tcttagaatt ctttttagct
    25081 caagaagcag aaaaaatgat tgcaaaggaa gcttaacaca gagctttctt ttttgctctt
    25141 agagagtttt tacaagcagc ttataaaata agaatttctg aatagacaaa ctcaaaaaat
    25201 ggctgggaaa tttaggaaaa aagcaagcac gattaaattt tttgtgttat aatattttgt
    25261 gaatagctat gcctatgttt agctatggaa taatacgaag tgcgaaactt ggaagataga
    25321 gaggaagcga tgtaatggct agagaaggct tttttacagg tctagatatt ggaacaagct
    25381 ctgtcaaggt gcttgtggcc gagcagagaa atggtgaatt aaatgtaatt ggcgtgagta
    25441 atgccaaaag taaaggtgta aaggatggaa ttattgttga tattgatgca gcagcaactg
    25501 ctatcaagtc agccatttcc caagcggaag aaaaggcagg catttcgatt aaatcagtga
    25561 atgtcggctt gcctggtaat cttttgcagg tagaaccaac tcaggggatg attccagtaa
    25621 catctgatac taaggaaatt acggatcaag atgttgaaaa tgttgtcaaa tcagctttga
    25681 caaagagtat gacacctgac cgtgaagtca ttacctttat tcctgaagaa tttattgtgg
    25741 atggtttcca agggattcgt gacccacgtg gcatgatggg ggttcgcctt gaaatgcgtg
    25801 gtttgcttta tacaggacct cgtactatct tgcacaattt gcgtaagacg gttgagcgtg
    25861 caggtgttca ggttgaaaat gttatcattt caccactagc aatggttcag tctgttttga
    25921 acgaagggga acgtgaattt ggtgctacag tgattgatat gggggcaggt caaacgactg
    25981 tcgctacaat ccgtaatcaa gaactccagt tcacacatat tctccaagaa ggtggagatt
    26041 atgtaactaa agatatctcc aaggttttga aaacctctcg caaattagcg gaaggcttaa
    26101 aactgaatta cggggaagcc tatccgcctc ttgcaagcaa agaaaccttc caagtagagg
    26161 ttattggaga agtagaagca gtcgaagtga cggaagccta cttgtcagaa attatttctg
    26221 cacgaatcaa gcacatcctt gaacaaatca agcaagaatt agatagaagg cgtctattgg
    26281 acctccctgg tggtattgtc ttaatcggtg ggaatgccat tttaccaggt atggttgagc
    26341 ttgctcagga agtctttggc gtccgtgtca agctttatgt tccaaatcaa gttggtatcc
    26401 gtaatccagc ctttgcgcat gtgattagtt tatcagaatt tgcgggtcaa ttaacagaag
    26461 ttaatctttt ggctcaggga gcgataaaag gtgagaatga cttaagtcat cagccaatta
    26521 gttttggtgg gatgctgcaa aaaacagctc agtttgtaca atcaacgcct gttcaaccag
    26581 ctcctgctcc agaagtagag ccggtggcgc ctacagaacc aatggcggat ttccaacaag
    26641 cttcacaaaa taaaccgaaa ttagcagatc gtttccgtgg cttgatcgga agcatgtttg
    26701 acgaataaag aggaaaaata aattatgaca ttttcatttg atacagctgc tgctcaaggg
    26761 gcagtgatta aagtaattgg tgtcggtgga ggtggtggca atgccatcaa ccgtatggtc
    26821 gacgaaggtg ttacaggcgt agaatttatc gcagcaaaca cagatgtaca agcattgagt
    26881 agtacaaaag ctgagactgt tattcagttg ggacctaaat tgactcgtgg tttgggtgca
    26941 ggaggtcaac ctgaggttgg tcgtaaagcc gctgaagaaa gcgaagaaac actgacggaa
    27001 gctattagtg gtgccgatat ggtcttcatc actgctggta tgggaggagg ctctggaact
    27061 ggagctgctc ctgttattgc tcgtatcgcc aaagatttag gtgcgcttac agttggtgtt
    27121 gtaacacgtc cctttggttt tgaaggaagt aagcgtggac aatttgctgt agaaggaatc
    27181 aatcaacttc gtgagcatgt agacactcta ttgattatct caaacaacaa tttgcttgaa
    27241 attgttgata agaaaacacc gcttttggag gctcttagcg aagcggataa cgttcttcgt
    27301 caaggtgttc aagggattac cgatttgatt accaatccag gattgattaa ccttgacttt
    27361 gccgatgtga aaacggtaat ggcaaacaaa gggaatgctc ttatgggtat tggtatcggt
    27421 agtggagaag aacgtgtggt agaagcggca cgtaaggcaa tctattcacc acttcttgaa
    27481 acaactattg acggtgctga ggatgttatc gtcaacgtta ctggtggtct tgacttaacc
    27541 ttgattgagg cagaagaggc ttcacaaatt gtgaaccagg cagcaggtca aggagtgaac
    27601 atctggctcg gtacttcaat tgatgaaagt atgcgtgatg aaattcgtgt aacagttgtc
    27661 gcaacgggtg ttcgtcaaga ccgcgtagaa aaggttgtgg ctccacaagc tagatctgct
    27721 actaactacc gtgagacagt gaaaccagct cattcacatg gctttgatcg tcattttgat
    27781 atggcagaaa cagttgaatt gccaaaacaa aatccacgtc gtttggaacc aactcaggca
    27841 tctgcttttg gtgattggga tcttcgccgt gaatcgattg ttcgtacaac agattcagtc
    27901 gtttctccag tcgagcgctt tgaagcccca atttcacaag atgaagatga attggataca
    27961 cctccatttt tcaaaaatcg ttaagtaaat gaatgtaaaa gaaaatacag aacttgtttt
    28021 tcgagaagtt gcagaggcta gtctgagtgc tcatcgagag agtggttcgg tctctgtcat
    28081 tgcagttacc aagtatgtag atgtaccgac agcggaagcc ttgcttccgc taggtgttca
    28141 tcatatcggt gaaaatcgtg tagataagtt tctggaaaaa tatgaagctt taaaagatcg
    28201 agatgtgact tggcatttga ttggtacctt gcaaagacgt aaggtgaaag atgtcattca
    28261 atacgttgat tatttccatg cattggactc agtaaagcta gcaggggaaa ttcaaaaaag
    28321 aagtgaccga gtcatcaagt gtttccttca agtaaatatt tctaaagaag aaagcaaaca
    28381 cggtttttcg agagaggaac tgctggaaat cttgccagag ttagccagac tagataagat
    28441 tgaatatgtt ggtttaatga cgatggcacc ttttgaggct agcagtgagc agttgaaaga
    28501 gattttcaag gcggcccaag atttacaaag agaaattcaa gagaaacaaa ttccaaatat
    28561 gcctatgacc gagttaagta tgggaatgag tcgtgattat aaagaagcga ttcaattcgg
    28621 ttccactttt gttcgtatag gtacatcatt ttttaagtag gagagaacca tgtctttaaa
    28681 agatagattc gatagattta tagattattt tacggaggat gaggattcaa gtctccctta
    28741 tgaaaaaaga gatgagcctg tgtttactcc agtaaattct tcacaggaac cggctctccc
    28801 aatgaatcaa ccttcacagt cggctggtac aaaagagaac aatatcacca gacttcatgc
    28861 aagacaacag gaattggcaa atcagagtca gcgtgcaacg gataaggtca ttatagatgt
    28921 tcgttatcct agaaaatatg aggatgcaac agaaattgtt gatttattgg caggaaacga
    28981 aagtatcttg attgattttc agtatatgac agaggtgcag gctcgtcgtt gtttggacta
    29041 tttggatgga gcttgtcatg ttttagctgg aaatttgaaa aaggtagctt ctaccatgta
    29101 tttgttgaca ccagttaatg ttattgtaaa tgttgaagat atccgtttac cagatgaaga
    29161 tcaacagggt gagttcggtt ttgatatgaa gcgaaataga gtacgataat gattttttta
    29221 attcgtatga tttataatgc agtggatatt tactccctga ttttggtagc cttcgctgtc
    29281 atgtcttggt ttccaggtgc ctacgaatcc agtttaggtc gttggattgt agcgttggtg
    29341 aaaccagtac ttgctccctt gcaacgcctg cctttacaga tagcgggtct tgatttatct
    29401 gtttgggtcg cgattgtttt ggttcgattt ttaggagaaa acctagtgcg ttttctggcg
    29461 atgataggat gaataaaggg atttatcagc atttctccat agaagatcgt ccatttcttg
    29521 acaagggaat ggaatggata aagaaggtag aagatagcta tgctcctttt ttaactcctt
    29581 ttatcaatcc tcatcaggag aagctattaa agattttggc caaaacctat ggtcttgctt
    29641 gtagcagtag tggggaattc gtctcgagtg agtatgttcg agttttatta tacccagatt
    29701 atttccaacc agagttttca gattttgaaa tatctctcca agaaattgtg tattccaata
    29761 aatttgaaca tttaacgcat gctaagattt tagggacagt catcaatcaa ttagggattg
    29821 aacggaaact ttttggagat atcctagtag atgaagaacg ggcgcagatt atgattaatc
    29881 agcagtttct tcttctcttt caagatggac taaagaaaat tggtcgtata cctgtttcgc
    29941 tggaggaacg tcctttcacc gagaaaatag ataagctaga acagtatcga gaactggatt
    30001 tatctgtgtc tagttttcga ttagatgttc ttttatcaaa tgttttgaaa ctatctagga
    30061 atcaagcaaa ccagttgatt gaaaagaaac ttgtccaagt aaattatcat gtggtagaca
    30121 aatcagatta cactgttcaa gttggagact tgattagtgt gagaaaattt ggtcgcttga
    30181 gattacttca agataaggga caaacgaaaa aagagaagaa aaaaataacc gtccagttat
    30241 tattaagtaa gtgaggaata gaatgccaat tacatcatta gaaataaagg acaagacttt
    30301 tggaactcga ttcagaggtt ttgatccaga agaagtcgat gaatttttag atattgtggt
    30361 tcgtgattac gaagatcttg tgcgtgcgaa tcatgataaa aatttgcgta ttaagagttt
    30421 agaagagcgt ttgtcttact ttgatgaaat aaaagattca ttgagccagt ctgtattgat
    30481 tgctcaggat acagctgaga gagtgaaaca ggcggcgcat gaacgttcaa acaatatcat
    30541 tcatcaagca gagcaagatg cgcaacgctt gttggaagaa gctaaatata aggcaaacga
    30601 gattcttcgt caagcaactg ataatgctaa gaaagtcgct gttgaaacag aagaattgaa
    30661 gaacaagagc cgtgtcttcc accaacgtct caaatctaca attgagagtc agttggctat
    30721 tgttgaatct tcagattggg aagatattct ccgtccaaca gctacttatc ttcaaactag
    30781 tgatgaagcc tttaaagaag tggttagcga agtacttgga gaaccgattc cagctccaat
    30841 tgaagaagaa ccaattgata tgacacgtca gttctctcaa gcagaaatgg aagaattaca
    30901 agctcgtatt gaggtagccg ataaagaatt gtctgaattt gaagctcaga ttaaacagga
    30961 agtggaaact ccaactcctg tagtgagtcc tcaagttgaa gaagagcctc tgctcatcca
    31021 gttggcccaa tgtatgaaga accagaagta gctccagtgc atccgacagg tccaacacca
    31081 gctacagaaa ctgttgattc agcaccagga tttgaagcac cgcaagaatc cgttacaatt
    31141 ttataagaaa cgatgtgaga acaatatctt atccttatat ttccagcgag caggagatgg
    31201 tgtgagtcct gcattcccta acgataagat tatcctctca aaaactcaag tctgaagcta
    31261 gtaagatttg acgtttccca cgttacggga taagagggag aaagactaaa tctttttccg
    31321 aataaaggtg gtaccacgat tttcgtcctt tttggaagtc gtggttttta atttgttatt
    31381 atttataaag gagataccat gaaactcaaa gataccctta atcttgggaa aacagctttc
    31441 ccaatgcgtg caggccttcc gaccaaagag ccagtttggc aaaaggaatg ggaagatgca
    31501 aaactttacc aacgtcgtca agaactaaat gaagggaaac cgcattttgt cttgcatgat
    31561 ggccctccat acgcaaacgg aaatatccac gttggacatg ccatgaatca tatctcaaaa
    31621 gatatcatca ttcgttctaa gtctatgtca ggttttaacg caccttatat cccaggttgg
    31681 gatactcatg gtctgccaat cgagcaagtt ttggcaaagc aaggtgtgaa gcgcaaagaa
    31741 atggacttgg ttgagtactt gaaactctgt cgtgagtacg ctctttctca agtttataaa
    31801 caacgtgatg atttcaaacg cttggggatg tcaggtgact gggaaaattt atatgtgact
    31861 ttaactccag actatgaagc agcccaaatc cgtgtctttg gtgagatggc taataagggt
    31921 tatatctacc gtggtgccaa gccagtttac tggtcatggt catctgagtc agcccttgcc
    31981 gaagcggaaa ttgaatacca tgatttggtt tcgacttcac tttattatgc caataaggta
    32041 aaagatggca aaggtatcct agatacagat acttatatcg tagtctggac aacaactcca
    32101 tttaccatca cagcttctcg tggtttgact gttggtgcag atattgatta cgttttggtt
    32161 caacctgcta gtgaaactcg taagtttgtc gttgctgcag aattgttgac tagcttgtct
    32221 gagaaatttg gctgggctga tgttcaagtg ttggcaactt accgtggtca agaactcaac
    32281 cacatcgtaa cagaacaccc atgggataca gctgtagatg agttggtaat ccttggtgat
    32341 cacgttacca ctgactctgg tacaggtatc gtccatacag cccctggttt tggtgaggac
    32401 gactacaatg ttggtattgc taatggtctt gaagtcgcag tgactgttga cgaacgcggt
    32461 atcatgatgg cgaatgctgg tcctgagttt gaaggtcagt tctacgacaa ggttgtacca
    32521 actgttattg aaaaacttgg taacctcctt ctagcccaag aagaaatctc tcactcatac
    32581 ccatttgact ggcgtactaa gaaaccaatc atctggcgtg cagttccaca atggtttgcc
    32641 tcagtttcaa aattccgcca agaaatcttg gatgctattg ataaagttaa attccataca
    32701 gaatggggta aagtacgtct atataatatg attcgtgacc gtggtgactg ggttatctct
    32761 cgtcaacgtg cttggggtgt tccacttcca atcttctatg cagaagacgg tacagctatc
    32821 atgacagctg agactattga acatgtggcg caactctttg aagtacatgg ttcaagcatt
    32881 tggtgggaac gtgatgccaa agacctctta ccagaaggat ttactcatcc aggttcacca
    32941 aacggcgagt tcaagaaaga aacagatatt atggatgtat ggtttgactc aggttcatca
    33001 tggaatggtg ttttggtaaa tcgtccaaat ctgacttatc cagctgacct ttaccttgaa
    33061 ggttctgacc aataccgtgg ttggttcaac tcatcactca ttacatctgt tgccaaccat
    33121 ggcgtagcac cttacaaaca aatcttgtca caaggtttta cccttgatgg taaaggtgag
    33181 aagatgtcta aatcacttgg aaataccatt gctccaagtg atgttgaaaa acaatttggt
    33241 gcagaaatct tgcgtctctg ggtaacaagt gttgactcaa gcaatgacgt gcgtatctct
    33301 atggatattt tgagccaagt ttctgaaact taccgtaaga ttcgtaacac tcttcgtttc
    33361 ttgattgcca atacatctga ctttaaccca gctcaagatg tagtcgctta cgatgaactt
    33421 cgttcagttg ataagtacat gacgattcgc tttaaccagc ttgtcaagac cattcgtgat
    33481 gcctatgcgg actttgaatt cttgacaatc tacaaggcct tggtgaactt tatcaacgtt
    33541 gacttgtcag ccttctacct tgattttgcc aaagatgttg tttacattga aggtgccaaa
    33601 tcattggaac gccgtcaaat gcagactgtt ttctatgaca ttcttgtcaa aatcaccaaa
    33661 ctcttgacac caatccttcc tcacactgcg gaagaaatct ggtcatatct tgagtttgaa
    33721 gctgaagact tcgttcaatt gtcagaattg ccagaagctc aaacttttgc taatcaagaa
    33781 gaagtcttgg atacatgggc agccttcatg gacttccgtg gacaagctca aaaagccttg
    33841 gaagaagctc gtaatgcaaa agttatcggg aaatcgcttg aagcacactt gacagtttat
    33901 ccaaatgaag ttgtgaaaac tctactcgaa gcagtaaaca gcaatgtggc tcaacttttg
    33961 atcgtgtcag acttgaccat cgcagaaggg ccagctccag aagctgccct tagcttcgaa
    34021 gatgtagcct tcacagttga acgcgctgca ggtcaagtat gtgaccgttg ccgtcgtatc
    34081 gacccaacaa cagcagaacg cagctaccag gcagtcatct gtgaccactg tgcaagcatc
    34141 gtagaagaaa attttgcgga agcagtcgca gaaggatttg aagagaaata aggttgaaaa
    34201 gtctaggcaa aattcaattt gagaagaaaa gacaactaat tttatagtct attaaacgca
    34261 ttgtatcacg tttttgaata cctgatatga tgcgtttttt atttatttta aaaatttgcg
    34321 aggtatgact ttttatactc aacaagaatc aaagagaaac ttagcaagct aacagtagta
    34381 agataaaata ggaatttgat attagggata agattgctaa atagtgtaat atttttacaa
    34441 taataaattt atatagttat ttttggtttc tgaaaagtat tatattttat ttcatattat
//
LOCUS       DAVHSY010000019        32749 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.019, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000019 DAVHSY010000000
VERSION     DAVHSY010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32749
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.019"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(<1..491)
                     /locus_tag="VVR43_001141"
     CDS             complement(<1..491)
                     /locus_tag="VVR43_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU6149506.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITN"
     gene            658..1980
                     /locus_tag="VVR43_001142"
     CDS             658..1980
                     /locus_tag="VVR43_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6149507.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            1982..3868
                     /locus_tag="VVR43_001143"
     CDS             1982..3868
                     /locus_tag="VVR43_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEU6149508.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYMRNKIILP
                     NSLEENLSYLFEWQKAFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGQMLWKKTRSYEELIEEYFSALYGENWQSVVEYLEKL
                     SIYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            4036..4380
                     /locus_tag="VVR43_001144"
     CDS             4036..4380
                     /locus_tag="VVR43_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6149509.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEAYGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            4390..5802
                     /gene="lacG"
                     /locus_tag="VVR43_001145"
     CDS             4390..5802
                     /gene="lacG"
                     /locus_tag="VVR43_001145"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU6149510.1"
                     /translation="MENLQFKVLPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGDANVLAVHYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKLGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            5871..7550
                     /locus_tag="VVR43_001146"
     CDS             5871..7550
                     /locus_tag="VVR43_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU6149511.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIVWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDISVMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLVTSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGVESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLMLVVDILIYLPFCRAYDRQLLMKEDVVSSNDIILEEETSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(7676..9115)
                     /locus_tag="VVR43_001147"
     CDS             complement(7676..9115)
                     /locus_tag="VVR43_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU6149512.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(9119..10468)
                     /gene="trkA"
                     /locus_tag="VVR43_001148"
     CDS             complement(9119..10468)
                     /gene="trkA"
                     /locus_tag="VVR43_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU6149513.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            10656..11504
                     /locus_tag="VVR43_001149"
     CDS             10656..11504
                     /locus_tag="VVR43_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU6149514.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            11519..12067
                     /locus_tag="VVR43_001150"
     CDS             11519..12067
                     /locus_tag="VVR43_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU6149515.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            12074..12331
                     /locus_tag="VVR43_001151"
     CDS             12074..12331
                     /locus_tag="VVR43_001151"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149516.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            12433..14115
                     /locus_tag="VVR43_001152"
     CDS             12433..14115
                     /locus_tag="VVR43_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149517.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQAAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNLSIS
                     KGQVQLQNELAKETPALQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            14100..14930
                     /locus_tag="VVR43_001153"
     CDS             14100..14930
                     /locus_tag="VVR43_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU6149518.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            15123..15626
                     /locus_tag="VVR43_001154"
     CDS             15123..15626
                     /locus_tag="VVR43_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU6149519.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      15680..15914
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            16079..16642
                     /locus_tag="VVR43_001155"
     CDS             16079..16642
                     /locus_tag="VVR43_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6149520.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            16656..17282
                     /locus_tag="VVR43_001156"
     CDS             16656..17282
                     /locus_tag="VVR43_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU6149521.1"
                     /translation="MKGSFALLLFVILGYMVKFYPETLVGFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            17309..17698
                     /locus_tag="VVR43_001157"
     CDS             17309..17698
                     /locus_tag="VVR43_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEU6149522.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRGGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            17703..18152
                     /locus_tag="VVR43_001158"
     CDS             17703..18152
                     /locus_tag="VVR43_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6149523.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            18280..18867
                     /locus_tag="VVR43_001159"
     CDS             18280..18867
                     /locus_tag="VVR43_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU6149524.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            19257..20864
                     /locus_tag="VVR43_001160"
     CDS             19257..20864
                     /locus_tag="VVR43_001160"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU6149525.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(21423..23054)
                     /locus_tag="VVR43_001161"
     CDS             complement(21423..23054)
                     /locus_tag="VVR43_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEU6149526.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGIGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIGLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            23343..28283
                     /locus_tag="VVR43_001162"
     CDS             23343..28283
                     /locus_tag="VVR43_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEU6149527.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHTRENKLEKAEGVATASETAEAASAAKPEEK
                     ASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            28373..29569
                     /locus_tag="VVR43_001163"
     CDS             28373..29569
                     /locus_tag="VVR43_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU6149528.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFHKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            29705..30232
                     /locus_tag="VVR43_001164"
     CDS             29705..30232
                     /locus_tag="VVR43_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU6149529.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            30309..30665
                     /gene="glnR"
                     /locus_tag="VVR43_001165"
     CDS             30309..30665
                     /gene="glnR"
                     /locus_tag="VVR43_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU6149530.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            30702..32048
                     /gene="glnA"
                     /locus_tag="VVR43_001166"
     CDS             30702..32048
                     /gene="glnA"
                     /locus_tag="VVR43_001166"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU6149531.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(32144..32263)
                     /locus_tag="VVR43_001167"
     CDS             complement(32144..32263)
                     /locus_tag="VVR43_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU6149532.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
BASE COUNT         9988 a         5731 c         7196 g         9834 t
ORIGIN      
        1 ttgtttgtaa tgatacttcc ggagtctttg ttataatgtc caggtattga taagccaaat
       61 ccaagtaatt ttgtttccaa agggacgtac tctatagctg tttttatcat attggtaatg
      121 gtggaattga tttctgaaat aggataatct tcattcaaaa tttctgtctc gaaaagagtt
      181 ttcccttgta agtcacatag actgagaaag atacctagga cgtttatttc aatacctcca
      241 acaacatacg gaatattatc tgtgatagaa atagtttttc tacgtcttcc agatccggaa
      301 aactcgctaa attcatcacc agtttcgtat atgagggact gttcgcttag ctcttttatg
      361 atgttagtcg ttgttgctgg agtaagtcct gtttcattaa caatatctgt acgggatgtt
      421 gctggatttc gatatagaaa ctccagtata gtggctctat tttgtaaaaa ggctgattgt
      481 tttgtaatca tttgtttcct cctttggttt attttatatt aaacataaga aaaaatcaat
      541 taaaattatt attctataca aagaaaaaat gttgtaaaaa caacaaaaaa tatattgaca
      601 acgctttctg ttagtggtat atttaattta taaaaaataa aaaaaggagt tccggtgatg
      661 aacaatattt tagcgttttt agaaacaaaa gtcgctccgt ttggtgaaaa agttggcaac
      721 caacggcatt tgaaagctat tcgtgaagga tttatgatgg caatgccttt gattttagtc
      781 ggctctttat ttcttattct aatcagttgg cctcaagagg attttacaaa ttggctgaat
      841 agtgttggat tgctaagtat cttgacaact atgaatcagt caacagtagc gattatctcc
      901 ttggtcgctt gtttcggtat tgcctacagg ttgtcggaag gatatggtac agatggtccg
      961 tcggcaggga tcatagcctt atccagtttt gtattgatgg cacctcgttt ttcgagtatg
     1021 gtttatgata aaaatgggga gcaggtcaag cagttatttg gcggcgcaat accattttct
     1081 agcctgaatg catcttcttt gtttatggcg attactattg gattggttac agcagagatt
     1141 tatcgtatgt ttatccagcg cggaattacg ataaaaatgc caagtggtgt cccagatgtg
     1201 gtaagtaaat cattttcagc tcttttacct ggctttacta cttttgtttt gtgggctctg
     1261 gtcttaaaag gtcttgaagc ggcaggagtt gcaggaggtc tcaacggact cctaggtgca
     1321 attgttggaa caccgcttaa gttaattgca ggaacgcttc caggtatgat tctatgtgtt
     1381 attgtaaact cattcttttg gttctgtgga gttaatgggg gacaagtttt aaatgctttt
     1441 gtagacccag tttggttaca atttactaca gaaaaccaag aagctgtggc tgcaggacaa
     1501 acactccaac acattattac attaccgttt aaagatttat ttgtatttat tggtggcggt
     1561 ggagcgacta ttggtcttgc gatttgtctc ttcctattta gtaagagtcg tgcgaataaa
     1621 acattaggta agctagctat tataccgtct atttttaata tcaatacagc tattctattt
     1681 acgtttccaa cagttttaaa tccgattatg ctgattccgt ttattgctac tcctacaatc
     1741 aatgccttga ttacctatgt atcaatggct gtaggattag taccctatac aacaggtgta
     1801 atccttccgt ggacaatgcc accgattata ggaggcttcc ttgcaacagg ggctagttgg
     1861 cgaggagctc tattacaagt tgttttgatt ttggtttctg tagcaattta ttatccattc
     1921 ttcaaaattg cagataaacg caatcttgaa aaagaaaaag ctactgttgg agggaaataa
     1981 gatggttatc agagtatttg atcaacagaa aaatacttat tctagctttg ccttagagga
     2041 attaagttac tatatgaatc gggtctttaa gactaacata gagcttgtcg aggagaagga
     2101 agcggatatt tttgtaggat tagtcaataa agaggacaga aaagaccatg ttcttatctc
     2161 attagacaag ggtaagggga gaattgagtc taatacaatt gtaggtttac ttattggaat
     2221 ttaccgaatg tttcatgaat ttggggttgt gtatactaga ccagggcgcg gacatgactt
     2281 tgttccagag ttacgatttg aagatttttt agataaacag ctatctatag atgaaacagc
     2341 cagttactat cataggggag tatgtataga gggagcggat tcatttgaaa atatactaga
     2401 tttcattgat tggctaccta agattgggat gaacagtttt ttcatccagt ttgaaaatcc
     2461 ttactctttt ttgaaacgtt ggtatgaaca tgaatttaat ccatatctaa ataaagaaca
     2521 attttcaaat gaattagtac aagaattgag tgataggttg gataaagaat tgcaaaaaag
     2581 aggtcttatt catcatcgtg ttggtcatgg atggacaggt gaagttttag gttactcttc
     2641 aaaatttggc tgggaatcag gtcttagtat ttcagaggag aagaaaccct atgtcgctga
     2701 aataaacggg aaacgagaat tgtttaatac ggctccgatt ttaaccagcc tggatttttc
     2761 aaatccagat gtagctgata agatggtaga aattatcaag gattatgcca agaaaagacc
     2821 tgatgttaac tacttacatg tatggttgtc ggatgctcgt aataatattt gtgaatgcga
     2881 aaactgtaga caagaattgg tttcggatca gtatattcgt attctcaatc aattggatag
     2941 ggctttaacg agtgagggat tagatacaaa gatttgtttt ctgctttatc atgagttgtt
     3001 atgggcacct cagaaagaaa aattagataa tcctgaacgc tttaccatga tgtttgcacc
     3061 gattacaaga acatttgaaa tgagttatgc agatgtagat tttgataatt ccatacctac
     3121 gcctaaacct tatatgcgta ataaaattat acttccgaat tctcttgagg aaaatttatc
     3181 ttatcttttt gagtggcaaa aagcatttaa aggagatagt ttcgtatatg actatccttt
     3241 agggcgtgct cattatggcg atttaggcta tatgaaaatt agtcaaacta tttacagaga
     3301 tgtatcttat ctttccaacc tacatttgaa cgggtacatt tcgtgtcaag aattacgtgc
     3361 cggattccct cataattttc ctaattatgt catggggcaa atgctctgga agaagacaag
     3421 aagttatgaa gaattgattg aagaatactt ttctgctttg tatggggaaa attggcagtc
     3481 tgttgttgaa tatttagaaa aattatccat ttattcctct tgtgattatt ttaatgcaat
     3541 tggcagtcgt caaaatgatg ttttagcgaa tcattattat atagcttaca atctagctga
     3601 taatttttta ccaattattg aggaaaatat ttctaagtta ttaaatagtc aaaaggatga
     3661 atggaaacag ctcagttatc atcgtgaata tgttgttaag atggcgaagg ctttatatct
     3721 tcaagcaact ggaaaaacaa ggcaagctca agatgaatgg agaaatgtgt tgaattatat
     3781 ccgtgggcac gaattgctat ttcaatctaa tttggatgtt tatcgtgtaa ttgaagtagc
     3841 aaaaaattac gctggtttcc acttataaat cataagtata gaaaatgaac taaggtattc
     3901 agggaagatt gaccctaaat attatgaaat ttaaggattt ttaagatatt tagggtcgac
     3961 tttctatttg tatcgtagcg aagtcatttt aataatgatg tgtaaaagat ggatcaagat
     4021 tgaggaggaa gaaagatgaa atcaaaagaa gaaataaata tgcttggttt tacaattgtc
     4081 gcttacgcag gagatgcaag gtcagatttg atggatgctt tggcgtttgc gagagatgga
     4141 tattttgaac aggcaagaga attggttgag tctgcaaacg actcaatagt gtctgcccat
     4201 cgagaacaga ctaatttatt agcggaggag gcatatggag ataattttga agtgagcttt
     4261 attatgattc atggtcaaga tactttgatg acaacgatgc tattgtatga tcaggtaaag
     4321 ttttttattg atgaatatga acgaattcga aagattgaag aacatattgg tttgcaatga
     4381 ggattagtca tggaaaattt acagtttaaa gtcttaccga aggagttttt attaggagct
     4441 gctaccgctg cttatcaagt agagggtgca actagggtag atggcaaagg aataaatatg
     4501 tgggatgttt atttgcaaga aaatagtccg ttcttaccag atccagctag tgatttttat
     4561 tatcgttacg aagaggatat agctttggcg gcagaacatg gtttgcaggc tttgcgttta
     4621 tctatttctt gggttcgtat atttcctgat atagatggag atgctaatgt attagctgtt
     4681 cattattacc atagagtttt tcagtcttgc ttaaaacata atgtgattcc gtttgtttct
     4741 ttacatcatt ttgattcgcc tcagaaaatg ttagaaacag gggattggtt gaatagagag
     4801 aatattgatc gtttcatacg atatgctcgc ttttgtttcc aagaatttac agaagtcaag
     4861 cattggttta caatcaatga actgatgtct cttgctgcag gtcaatatat aggaggtcag
     4921 tttcctccaa atcatcattt tcaattatct gaagcaattc aagcgaatca taatatgttg
     4981 ttggcgcatg ctcttgcagt cctcgaattt catcaattag ggattgaggg aaaggtaggt
     5041 tgtattcatg ctttaaagct aggctatcct attgatgggc aaaaagaaaa tattttggca
     5101 gctaaacggt atgatgttta taataataaa tttctattag atggaacttt tttgggctac
     5161 tacagtgagg acacgctttt tcacttgaat caaatattgg aagctaataa ttctagcttt
     5221 attattgaag atggtgattt agaaattatg aagagagctg cagctcttaa tacgatgttt
     5281 gggatgaatt attatcgttc agaatttatt cgtgaataca aaggtgaaaa tagacaagaa
     5341 tttaattcaa caggaataaa aggacagtct tcttttaaat taaatgctct aggtgaattt
     5401 gtaaaaaaac ctggtattcc gacaacagat tgggattgga atatttatcc tcaagggtta
     5461 tttgatatgt tgcttcgtat caaagaagaa tatcctcaac atccggtcat ttatttaact
     5521 gaaaatggta cagcccttaa agaagttaag ccagagggcg agaatgatat tattgatgac
     5581 agtaagagaa tccgttatat tgagcaacat ttacacaaag ttttagaggc tcgagatagg
     5641 ggagtcaata ttcaaggcta ttttatatgg tctttgcaag atcaattttc ttgggcgaat
     5701 ggctacaata agcgatatgg tcttttcttt gttgattatg aaacacagaa gagatatatt
     5761 aagaaaagtg ctctttgggt aaaagggcta aaacggaatt aaggttagcg atttgactga
     5821 tgtttaatat attttaacta tgagcttaaa ttttttataa gaggagtttt atggataagc
     5881 tagtcgctgc cattgaaaag caacaaggga aatttgaaaa aatttctact aataactata
     5941 tgatggctat taaagatgga ttcattgcta ctatgccttt aattatgttt tcaagctttt
     6001 tgatgattat tattatgatt cctaaaaatt tcggagtaga gttaccgagt ccagctattg
     6061 tctggatgag aaaagtgtat atgttaacca tgggagtttt gggtgttatt gtttcaggga
     6121 cagttgcaaa gtcattggct ggaaatgtta atagaaaaat gcctcctgga aaggtaataa
     6181 atgatatttc tgtaatgttg gcagccatat gtagttatct ggtattaact gtaacgcttg
     6241 tagttgatga gaagacggga tctacaagtt tgtcgacaaa ctatttagga tctcaaggat
     6301 tggtaacttc gtttgtcagt gcctttatta ctgtaaatgt ttaccgattc tgtattaagc
     6361 gagacattac tattcattta cctaaggaag ttcctggggc tatatcacaa gcttttagag
     6421 atatttttcc tttttctttt gttttactta ttagtggttt gttagatatt gtatctcggt
     6481 ttagtttaga tgttcctttt gcccaagtat ttcaacaact attgactcct atttttaagg
     6541 gggtagaatc atatcctgct atgatgttga tttggtttat gtgtgctttg ctttggtttg
     6601 ttggaattca tggaccatct attgtcttac ctgctgttac agctttacaa ctgagcaata
     6661 tggaagagaa tgctcaactt cttgcaaatg ggcagttccc ttatcattct ttaacaccta
     6721 atttcgggaa ttatatcgct gctattggag gaacgggggc tacctttgtt gtaccattta
     6781 ttttgatttt ctttatgcgg tctaaacaat taaaatcggt aggtaaagct acaattactc
     6841 ctgttttatt tgcggtaaat gaacctcttc tatttggtat gcctgttatt ttgaatccct
     6901 atctttttgt cccttttttg atgactccac cagtaaatgt atttctagga aaggtcttta
     6961 ttgatttctt tggaatgaat ggattttata tccagttacc ttgggccttt cctggtccct
     7021 tgggattgtt aattggaacg aattttcaat ctatctcctt tgtattttta tctttgatgt
     7081 tagttgtcga catattgatt tatttgccat tctgtagagc gtatgataga cagttactga
     7141 tgaaagaaga tgttgtaagc tcaaatgata ttattttaga ggaggagaca agtgaaataa
     7201 tgcctggtga gatagatgta ataaaaagta aggagttgaa agtactggtt ctttgtgcag
     7261 ggtctggaac aagtgcgcaa ttagccaatg caattaacga gggcgctcaa ttagcagaag
     7321 ttagagtgat tgcgaattca ggagcgtacg gagctcatta tgatattatg ggtgtttatg
     7381 atttaattat tctggctcca caagttcgga gttattatag agagatgaag gtggatgcag
     7441 aaagattagg tattcagata gttgctacca gaggaatgga atatattcat ttaacaaaga
     7501 gtccaagtaa agccttacaa tttgtattgg agcattacca agctgtgtag taagtttttc
     7561 catcttttat ttgagtaaag attttgctta cagataggct tggatttaaa aacgttcccc
     7621 cttttttaat ataagaatcc ctctttcaca attgtaaaaa gagggatttt gtattttatc
     7681 tcttagacca agttctcttc ataaagagaa ggaggattgg gtaaatctcc aagcgccctg
     7741 caatcattgc aaaggatagg agaatttttg agatgggact aaagattgag aaactagaag
     7801 tggttcctag aataggcccg atattattga aacagctaaa gacagcgctg gtcacgacca
     7861 gaaaatcatt gctatctagg ctgacaataa agataagcgc tagcaaaatc atagcataga
     7921 tgacaaagta cttgagaatc ttatgctggg tatctttgtc aatcaccgtt ttattaacat
     7981 ggagggtcaa aacacggtgg ggcgatagga ttgacaaaat ttggtttttg gcaatttttg
     8041 aaaggatgag gcctcgaata atcttgagtc cacctgcagt tgatccagca gagccaccga
     8101 ttgccatgag gaaaaggagg ataaactggg agaagagggg ccagttggta atatctccat
     8161 atccaaaacc agttgttgta atgatgttgg aaacctggaa gaaggtcatt tcaaagctct
     8221 ttgaaaaccc tgggtagagg tagagggtgt tgaggctaat caagcctgta gaaaccagta
     8281 caatgaccaa gtaagcccga agttcttcgt caccaaagaa ggccttgatg cgacggagca
     8341 tgaggtagta gtagaggttg aaatttaccc caaaaaccag aactccgata ctgaccagat
     8401 aggtaatcag tgagctgcca tagtgggcaa ttccgtcgtt atagacggta aagcctccag
     8461 ttcccgctgt ccccatagca atgacaaaac tatcgtagag aggcatacca gctagataat
     8521 agatgatgac aaagagggag aagagagcta gataaaggag atagagaatc tgggcagtgt
     8581 tttttagttt ggatacaacc ttgccaaaaa caggacctgg aacctcagcc ttcatcacct
     8641 ctaggtggct atttttggca ttgtccataa tagcaagtgc aaaaacaagc actcccatcc
     8701 ctccaatcaa gtgggtaaaa cttcgccaga agaggaggga acggctgaga accgaaacgt
     8761 cgttcaaaat acttgctcca gtagttgtaa acccagaact aatttcaaaa aaggcatcaa
     8821 taaggctggg gatttgccca gaaaagacaa aggggagacc accaaagaaa gaccaaagga
     8881 tccaacagag ggcaacgatc aagactccct ccttggcata aatccgttga ttttttggct
     8941 tctgtaaact ccctgaaccg cctaacaata cgagaatccc tatggtcgaa aagagggctg
     9001 taaagacttg gctcgattca cggtaataga cagcgatagc cacaggaacc aagaggagaa
     9061 cagcttcaat caaaagtaac tttgaaagga ggtaacgaat catactttta ttcatttctt
     9121 acctcgcaat caagtcataa atcttggtga tgtttggcaa caaggttgtt actaggagct
     9181 tgtctccaac ttccaacata tcctccccag ttgggaaaat agtcttgccc tttcgaataa
     9241 tggctgcaat aagaacccct tttttcaatt tcagttgaga aagaggtttg gcagtcattt
     9301 tattggcttc cttgatatgg aattgcaggg tttcgatttg gccattggct agatggtgca
     9361 tggcttgaag gtctgaatac tgggcattaa ctcgaccacg aataaagtgc ataatcgtat
     9421 ctacagcgat gcttttaggt gtgatgatac ttgaaaaatc aggcgcattg ataatctcga
     9481 ggagactggt acgattgacc ttagtaatat ttttctgtac acctaccctg tcaaggaaca
     9541 tagatgtaat cagattttcc tcatcgactc ctgttagagt cgcaacggca tcatagtgtt
     9601 gagcactttc ttccagcagg atatcttttg cggttccatc tccttgaacg atgtagagat
     9661 ttgggaattt ctcgctaaag aagctggcga tttcaggatt gatttcaatg acttttgtat
     9721 cgatacgact atctttgaga ataccaagta gataataggc aattctacct gctccaacga
     9781 tgagaaggct cttcacggcg cgtgatttaa aataattatg gaagagtatc atatcgacac
     9841 ggttaccagt gacaaagatt ctatctttat cctgtacagt catgtcaccg cttggaatga
     9901 taatttgatg atccctctct atcgcacaga caatgacatt accaaatttt ttacgaaaat
     9961 cagaaatggg catttggcaa agaccgctgg tggacttgac gacaaattcc atgaggctaa
    10021 cgcgtccacc agcaaagcgt tcgacagaca gggcgttggg gaagtcaatg atattcgcga
    10081 tagcgcgggc agccaagagc tcaggattaa cgataagaga aaaaccgaga atattctttt
    10141 ccttgaaata agagttagaa tattcagggt tccgcacccg aacgatagtt tctttagctc
    10201 ccattttctt ggctagaact gctgcaatca tgttgacttc atcgtgctca gtcagggcga
    10261 taaagatatc acaatcttgg acgctggctt gctcaagaat ggcaaaatcg gccccgttac
    10321 caaggatacc aatgatatca aagcgactga caatatgatt gagaacagct tcgtcttgct
    10381 caatcagcaa aacatcatgc ttttctgcaa ccaaggagcg acagagggca aaaccaactt
    10441 ttccccctcc gacaaggata attttcataa taaaacctac tttttcatga tgtaactatc
    10501 ataccctttt tcaagaaaaa atgcacctac tagctaataa caagagcttt tagtgaaaat
    10561 tcgctataag gtaaaactat accctaacca attgaaatag ctattagcga ctttctctga
    10621 aatatggtat gataaaggat atacaaggag ataaaatgaa taataattta ctggtattac
    10681 aatcagactt tggtctggtt gatggtgcgg tatcggctat gattggagtg gctttagaag
    10741 agtctccaac cttaaaaata catcacttga cgcacgatat cacgccttat aatatttttg
    10801 aggggagcta tcgtctcttt cagacggtgg attactggcc tgagggaacg acgtttgtat
    10861 cggttgtcga tccaggtgtc ggttcgaaac gtaagagtgt agttgccaag actgcaaaaa
    10921 atcaatacat tgtcacgcca gataatggga cgctttcctt tatcaagaaa cacgttggca
    10981 ttgtagccat tcgtgagatt tctgaggtgg ccaataggcg tcaaaacaca gagcattctt
    11041 ataccttcca cggtcgtgat gtctatgcct atactggtgc taaactggcc agtggtcaca
    11101 ttacttttga ggaagtaggg ccagagctca gtgtggaaca gattgtagag cttccagtcg
    11161 tagcgaccat catagaagat catctggtga agggagccat tgatattctg gatgtgcgtt
    11221 tcggttcgct ttggacctct atcacacggg aagaatttta caagctggaa ccagaatttg
    11281 gtgatcgttt tgaagtgacc atctatcatg ctgatatgct ggtctatcaa aatcaggttg
    11341 tctatggcaa atcatttgca gatgtgagaa ttgggcaacc catcctttac atcaactctc
    11401 tctatcgttt aggtttggct atcaaccaag gttcctttgc caaggcctat aatgtaggtg
    11461 tcggttcatc ttggaccatt gaaataaaga aaatagaagg ataaaatagg agaatagtat
    11521 ggaaatcaaa tttacaatta aacaagttgt tgctgtcgga attggcgctg ccctctttgt
    11581 cgtcatcggg atgatcaaca ttccaacccc tgttccaaat acaagcatcc agcttcagta
    11641 tgcggtacaa gcgctacttt ctattatttt tggaccgatt atcggtttgc ttgtcgggtt
    11701 gattggtcat gcaatcaagg actctcttgt tggttatggt ctatggtgga cttggattat
    11761 cgctagcgga ctctttggtt tagttgtggg actttttaga aagtacgttc gcgtgatcaa
    11821 tggtgttttt gactggaaag atattcttat ttttaatctc attcaactac ttgcaaatgc
    11881 ccttgtttgg ggtgtcttgg caccacttgg agatgttgtg atttatcaag aagcggcaga
    11941 aaaagtattt gcacaaggga ttgttgcggg aattgccaat ggtgtatctg tagctattgc
    12001 aggaactctt ctcttacttg cctatgcagg aactcaaact cgtgcaggaa gtttgaaaaa
    12061 ggactaatac tcaatgaaaa tcaaagagca aactaggaag ttagccgcag gttgctcaaa
    12121 acagtgtttt gaaattgtgg atagaactga cgaagtcagc tcaaaacatg gttttgaggt
    12181 tgtagatgaa actgacgaag tcagtaacca tacctacggc aaggcgaaac tgacgtggtt
    12241 tgaagagatt ttcgaagagt ataaaatgat ggggaaggct gggcaactag tctttttcga
    12301 tgtttataga ttagttaggc aagtaagcta agataggaat ctttttggcg ctaagatttt
    12361 aagagaagag actgcaagaa gggcttgatt tatgataaaa tagaagtcta agaagcgaat
    12421 gaagagagta agatgaaaga agctataatt gagtggaagg atttctcttt ccggtatgaa
    12481 acacaacaag aaccgacctt gcaagggata gacttgacca tttacaaggg agagaaagtc
    12541 ttaattgttg gaccatctgg atcaggtaaa tctacattgg gtcagtgttt gaatgggatt
    12601 attcccaata tttacaaggg tcagacatat ggagaatttt tgataaaggg tcaagcagcc
    12661 tttgatatga gcatctatga taagtctcat ctggttagca cagttttgca ggatacagat
    12721 gggcagttta ttggcttgtc tgtggcagaa gatttggcgt ttgctctgga aaatgatgtg
    12781 acagccctag atgagatgaa aggtcgtgtt tataaatggg ctgaaaagct ggaccttctt
    12841 cctttactgg atcagcgtcc tcaggatttg tcaggtggac aaaagcagcg agtcagtctg
    12901 gctggtgtct tgattgatga aagtccgatt ctcttgtttg atgagccact cgccaatcta
    12961 gatcccaagt caggtcagga tattatcgaa ttgattgacc agattcataa ggaagagggg
    13021 acgacgactc ttattatcga gcaccgtttg gaggacgttc tgcatcgccc tgtggatcgg
    13081 attgtcttga taaacgatgg tcgtatcctt tttaatggga gccctgacca gttgcttgcg
    13141 actgatttat tgactcaaaa tggaattcga gaaccccttt atctaacgac tctccgtcaa
    13201 ttaggtgtgg acttagtcaa ggaagaacaa ttagcgaatc tggataactt gtctatctca
    13261 aaaggtcagg ttcagttgca gaatgaactg gcaaaagaaa ccccagcatt gcagtcactc
    13321 tttagactag aggaagtatc tttttcttat gatgatagac cgattttaaa atccctacat
    13381 ttagatatta aaaagggtga aaagattgct attgtcggaa aaaatggagc agggaaatca
    13441 actctagcca aggctataag tagctttatt cagacggaag gacgctatct ttgggaaaaa
    13501 caggatataa aaggcgattc tgttgcagag cgggcggaac gagtaggata tgtgctacaa
    13561 aatcctaatc aaatgatttc aaccaatatg atttttgatg aggtggctct agggctccgt
    13621 ttgcgaggtg tggatgagaa ggaaattgaa acgagagtat atgaaacctt gaaaatctgt
    13681 ggactttatg aattccgtaa ttggcctatt tctgccctgt catttggtca gaaaaaacgt
    13741 gtcaccattg cttcaatttt ggtcttagga gctgaaatta ttctcctaga tgaaccgact
    13801 gcaggtcaag atcagaagaa ctatactgag attatggaat ttctcgaaga gttacatcaa
    13861 aaagggcata ccattgtcat gattacccat gatatgcaat tgatgctgga ttattcagac
    13921 cgggtccttg tcatggtgga tggagaattg attgccgata ctgttccagc cagtctgttg
    13981 agcgatcctg agctgttagt aaaagccaat ctaaaagaaa cctccatctt taacttggct
    14041 aagaaactag atgtggatcc actggattta acggcatttt acaaagaaag gagagaggga
    14101 tgcaagctaa attaatcggt taccagcata gagatactgt gattcatcgc ttgtcaggag
    14161 ctgggaaact tctctttttc attctggtat cattggcggc catgattagc tatgatacca
    14221 gaatgctctt gctgattgcc atcttttcag tctttctcct ctatttatca gaaattcgct
    14281 ttaaagatgt ttcctttgta gccgtttttg cgacggtatt tgccgtttta aacgttttga
    14341 tggtctatct cttttctccc gagtatgggg ttggacttta tggagagaga agtgtgattt
    14401 ggcagggaat cggtgtctac actctaacca gccaggagct cttttatctg ctaaatttgg
    14461 ccattaagta tctttgcacc attcctctgg ctattatctt tttgatgaca acccatccta
    14521 gtcagtttgc ttccagttta aatcaaattg gtgtgcccta taagattgct tattctgtca
    14581 gcctgacctt gcgctatatt ccagatttgc aggaagaatt ctttactatc aagatgtctc
    14641 aggaggcgcg tgggatggaa ttatccaaga aagcttctct tatgcaacga atcaaaggca
    14701 atctgctcat tattacgccc ttgattttta gctcgctaga acgcattgat accattgcga
    14761 ctgccatgga gcttcgccgc tttgggaaag agaaaaaacg cacatggtat agttatcagg
    14821 ccttgaaaaa aggagactat attaccttgc tcttggcaac cttgttttta gtagttagtt
    14881 tactacttat cttgcagaat cagggacgat tttacaaccc ttggaaatag cttgaaaaaa
    14941 ttgaaaaaat caagtcattt ctattgacaa tgattctgaa agtgttatac taagaaagta
    15001 gtttcgctga tttacttcaa acctgttgtg aggtaagtta acgatgcctt aaccacgctg
    15061 tttgctgagc ttgactccgg gcagtgtggc tatttttttg caatggtgaa aggaagcaag
    15121 tcatgacaaa tcacattgta ttatttgaac ctcaaattcc acaaaataca ggcaatatcg
    15181 cgcgtacttg cgctgcgacc aattctcccc tccacatcat caagcctatg ggctttccta
    15241 ttgatgaccg caagatgaag cgggctggat tggattactg ggataagcta gagatttatt
    15301 tttacgagag tttagaagat ttcatatctc agatgaaggg aaaactctat ctgatttcga
    15361 aattcgcgga aaaaatctat tctgaggtgg atttatcgac tgacgaggac cattattttc
    15421 tctttggacg tgaagacaag ggcttacctg aagattttat gcgagaacat cctgagaagg
    15481 ctctccgtat tcccatgaat gatgaacatg tccgcagtct caatgtgtct aataccgtct
    15541 gcatgattgt ctatgaggct cttcgccagc agaactttgc aggtcttgaa ctcgtccata
    15601 cctatgaagt ggataaattg aaataaaaaa tgaaaatgaa caaaatgctt gcgcttgcaa
    15661 gcgttttttg ttatgataaa agagtcttca gggcagggtg tgattcccga ccggcggtga
    15721 ctttaactag gaaatgatct tttcctttta tactttgttg acaagctttg cctaaccaga
    15781 agttatgcct acagcttgtc gcctagtcta aaagaaaaat ctctatttcc ttctctttaa
    15841 agaagtccgc gagcgcaagc tgatgtggtg agattccaca accgacagta tagtctggat
    15901 gggagaagac gaaagaatag ctttgtctgt tttgatagat ttatagccgg attgtaacca
    15961 cttgctttgt ttttctttaa tagagtaaga gggaactttt gggatataaa aagtgagaat
    16021 agatagagga atcctttcca acttcttctg attttataga aaattggagg aacctgttat
    16081 gacaaacaca cgtcgacttt cgaccattgc aattctatca gccatctcat ttgtgctgat
    16141 gtactttgac tttccgcttt taccagcggc atctttcctc aagatcgaat ttagtatctt
    16201 gccagtcctt gttggtctgg tggtcatgga tttgcctgct gctctaggag tgctcttgct
    16261 tcgctcacta ttgaaattgc ttcttaacag ccaaggagtg aatacttaca ttggtttgcc
    16321 gatgaatatc gtagctttgg gagtttttgt catcgtattt gctttgattt ggaaaaagga
    16381 acggacaacc cttcgtttcc tactaggctc tctagctgga actgttggtt taaccttggc
    16441 catgttggtt ctcaactatg tttatgctgt tcctttgtac gctaagtttg ctaactttga
    16501 tattggaaaa attttgggac tttccaacta cctaatgacc atggtattac cttttaactt
    16561 gattgagggt gtaatctttt ccgtttcatt ctggttgttg tatgttctct tgaaaccaac
    16621 cttaaaacat tatgagagat aaacaaacat ttttaatgaa gggcagtttt gcccttttac
    16681 ttttcgttat tcttggctac atggtcaaat tttaccctga aacgctggtc ggttttgacc
    16741 aatcgattca gactgccatt cgaggagact taccagatta tttgactatt ctttttcgat
    16801 ccctcacacg tctgattgat attccagtga ttatcacttg ggttgtcatt atagcttttg
    16861 tcttttatcg taagcgatgg aagatagaaa gtttcttcat gctgggaaat ctggctttgg
    16921 caggtctttt aatcgtgacc tttaaaaata tctaccagcg cccacgacca gctattttac
    16981 atctggtgga ggagaaggga ttttccttcc caagtgggca ttctctagct gtaacgctga
    17041 tggtagggac tttgattgtt attcttagtc agcggattaa agatcaggtc tggagaaaaa
    17101 tcgtacaaat cgtccttggc ctctacctag tcagtgtgct ggtatcaaga gtctatctgg
    17161 gagttcatta cccatcagac gtccttgcca gtctctgtgt gggcttggga gtcctgttta
    17221 tcgagtttcc cttttatgac aagctccgct tccaatggcg atttaaaggc aaacagaagt
    17281 gagtatcgaa ttcccttgag agaaagaaat gaaagtcaat atagcagatc ttcatccgac
    17341 tcaactatat ttatcagaaa agaagttgca agatattcag atgctttacc agtcggcaga
    17401 aacaatccaa gtcgatccaa tcagtattct tgcctttgga gattgtttgc tgattacaga
    17461 tgggcatcac agggcttatc aggctttatt ggcaggtcgg gatacgattt ctgctgagtg
    17521 ggatagaggt ggtggtgatg aactatatca tctctatgcg caagcttgcg aggaaagaaa
    17581 gatttactct gtttttgatt tagaagatcg tatcctagct caagatgggt atgaagcaaa
    17641 atggtataac tggtgtgatg gttttaatca agcagcaact cttttgttga aaaggtagtg
    17701 cattgtgttt tgttccttat tataaggtca attattgtga ggaagctttt gcttggtatc
    17761 aggatgtgaa cttggtttac ctcgtagatg gggtgaagct tccttacagt caagcgacct
    17821 tggaagccat gtattcctat ttggatcggc atggtgagct tttttggatt gaagtcaagg
    17881 agaagggaga atggtttcca attggggata ttacactatc tcaggataat ctccccattg
    17941 tgattgggaa ttccgcttac caacatcgag gacttggaaa aaagattcta agtgctttga
    18001 ttgaattggc tcgagtaaaa ggatggaaag aattgagagt caaggaaatc tacacctaca
    18061 atcatgcttc taggaggtgt ttcaagtcgc ttggatttgt ggaaaatgga gcaacagaaa
    18121 aaggaaggag ttttatattg gaattagtct aatcctgcca ctttctcccc cttaaccttt
    18181 gactattccg caaaattatc gtaaaataaa gagtaaatga taaaatgagg tcagagtctg
    18241 ttcgctctgg cgatagtagt ataaatgagg agaaacgctt tggaattaga agtatttgct
    18301 gggcaagaaa aaagtgaact atctatgatt gaggtagcgc gtgctatctt ggaacttcgt
    18361 ggtcgcgatc atgagatgca ttttagcgat cttgtaaacg aaattcaaaa ctaccttgga
    18421 acatcaaaca gcgatatccg cgaagctttg cctttgttct acacagagtt gaactttgac
    18481 ggtagcttca tctcacttgg ggacaacaaa tggggtcttc gttcatggta tggtgtggac
    18541 gaaatcgacg aagaaatcat cgctcttgaa gaaaatgacg acgatgaagt agcaccaaaa
    18601 gctaagaaaa aacgtgtcaa tgcctttatg gatggtgatt cagatgccat tgactacaat
    18661 gcagatgatc cagaagacga agatgcatac gaagcagatc cagctctttc atacgatgat
    18721 gaaaatccag atgatgaaaa aaatgaagtg gaagcttatg atgcagaaat caacgaaatc
    18781 gctccagatg acttgggaga agatgtggat ctcaacgaag acgacgacga gttttcagat
    18841 gacgatgctg aaaccagcga ggaataagag ttagctattg acaattatcc tatttttagg
    18901 tatcatattg tttgggcacc tcttttagag gtcggggctc cctagttctt agggagctat
    18961 ttttgttttt tcaagaagtt atcttcttgt attttatact caatgaaaat caaagagcaa
    19021 gctaggaaac tagccgtagg ctgctcaaaa cactattttg aggttgtaga taagactgac
    19081 aaagtcagga acacatatct acggcaaggc gacgttgacg cggtttgaag agattttcga
    19141 agagtattag ctgtgaatct ggtgcagtcg tcccagatta ttcttattag tagggtcttg
    19201 ttttctatat cccctcgtag ttaacaagac cttgagcatt ttagaaagag gaatctatgt
    19261 ctacgaaata tatttttgta actggtggtg tggtatcgtc tattgggaaa gggattgtgg
    19321 cagcgagtct aggccgtctc ttgaaaaatc gtggtctcaa agtaaccatt caaaagtttg
    19381 acccttatat caatattgat ccgggaacca tgagtcctta ccagcacggg gaagtttttg
    19441 tgacagatga cggagctgag acagatttgg acttgggtca ctatgaacgt ttcatcgata
    19501 tcaatctcaa caaatattcc aacgtgacaa ctgggaaaat ttacagtgaa gttcttcgta
    19561 aagaacgccg tggagaatac cttggggcaa ctgttcaagt cattcctcat atcacagatg
    19621 ctttgaaaga aaaaatcaag cgtgccgctc taacgaccga ctctgatgtc attatcacag
    19681 aggttggtgg aacagtagga gatatcgagt ccttgccatt cctagaggct cttcgtcaga
    19741 tgaaggcaga tgtgggtgcg gataatgtca tgtatatcca tacaaccttg cttccttacc
    19801 tcaaggctgc tggtgaaatg aaaaccaaac caacccaaca ctctgtcaaa gaattgcgtg
    19861 gcttgggaat ccaaccaaat atgttggtta ttcgtacaga agagccagct ggtcaaggaa
    19921 ttaaaaataa actggcccag ttctgtgatg tggcaccaga agccgttatc gaatcgttgg
    19981 atgttgaaca cctttaccaa attccactga acttgcaggc acaagggatg gaccaaattg
    20041 tttgtgatca tttgaaatta gacgcaccag cagcggatat gacagaatgg tcagccatgg
    20101 tggacaaggt catgaacctc aagaaacaag ttaagatttc ccttgttggt aagtatgtgg
    20161 agttgcaaga tgcctatatc tcagtggtcg aagccttgaa acactctggc tatgtcaatg
    20221 atgtagaagt taaaatcaat tgggtcaatg ccaatgatgt gacagcagag aatgtagcag
    20281 aactcttgtc tgatgcggac gggatcatcg taccaggtgg ttttggtcaa cgtggtacag
    20341 aagggaaaat ccaagccatc cgctatgcgc gtgaaaatga tgttccaatg ttgggagtct
    20401 gcttgggaat gcagttgaca tgtatcgagt ttgctcgtca cgttttaggt cttgaaggtg
    20461 ccaattctgc agagcttgca ccagaaacaa aataccctat cattgatatc atgcgtgatc
    20521 agattgatat tgaggatatg ggtggaaccc ttcgtttggg actttatccg tctaagttga
    20581 aacgtggctc taaggctgct gctgcttatc acaatcaaga agtggtgcaa cgccgtcacc
    20641 gtcaccgtta tgagtttaat aatgccttcc gtgagcagtt tgaggcagca ggttttgtct
    20701 tttcaggagt ttctccagac aatcgtttgg tagaaatcgt ggaaattcct gaaaataaat
    20761 tctttgtagc ttgtcagtat caccctgaac tgtcaagccg tccaaaccga ccagaagaac
    20821 tctacactgc ctttgttact gcagcggttg agaacagcaa ttagcaaaat cagaaccttt
    20881 gagaaaaatc tcagaggttt tttgcataca atgatattgc agtatatctg aggtaggagt
    20941 cctctgtatg tacctgctac cgttgaaatt aatagcgact ccctcttgcc ctgtgctagt
    21001 gaatggattt atcagtatat tgaaatgaaa taaaatctga acaaattaat tcggaaagcc
    21061 aaatcaattt ctagcaaagt tttaggaact ggattgtata gtgaattgaa ataagatgtg
    21121 aacatctcta tcaggaaagt caaattaatt tatagaaata ttttagcagt caagatggac
    21181 tgttatagat tcaatacatt atactttttt aatttaatcc actatagtaa aatgaaataa
    21241 taacaggaca aatcgatcag gacagtcaaa tcgatttcta agaatgtttt agaaatagag
    21301 gtgtactatt ctagtttcaa tatactatat atctgcagaa tactctttca gtttcattca
    21361 gcctagtctt gcttaggaaa aagtaagaag ccatccaatt atgatggata gcttcttggt
    21421 tcttagattt gttctgcaaa aaccttttca gcaaggttca tagcgtggtc tgatacacga
    21481 gtgtagtgtg agatgatgtc gataaagttg accccagctt gtgttgaaca ttcgcctttg
    21541 ttgaggcgtt tgatgtgggt ttttctgaga acacgttcta tcttattgat tgcttcatga
    21601 cgttctacaa gactgcgtgc tttttcaata tcattgtttt ccacactatc cagagcatct
    21661 ttgataaagt cactagtttg gcggtaaact tcctctaatt ctttcaaggc ggcatcagaa
    21721 aattcaacat ttttccgttg aagatagtca gtcagattga gtagagcctc cgtgtggtct
    21781 ccaatccgtt ccaaatcacg ggaggaatca aggatattgg taagcacttc actttctttt
    21841 tggctgagag cttcgcttga aagggcaatg agataacgtg ttaattgctc atcgatggtg
    21901 ttaattgctt cttcggtttt atgccctttt tcagcaactt tttcatccaa gccaatgatg
    21961 tacttatagg aaaggtcaaa ggctttagca gcgtagtttc ctaagtgcaa gagctctttc
    22021 ttagcatttc ctagagcgat agatggggcc tgtttgatga aatgttcatc aagatataag
    22081 ggttcgtatt tgacaacctc gtcctctcca ggaataatct tggttacaaa gtaagccaga
    22141 gctccgataa atggaaattg gacaatggtg ttggtaatat taaaggttcc gtgagcaaag
    22201 gcgatggtca tttccggtgc tagatttagc gtagcttcaa accaatgaat caggacagta
    22261 aaaggaacta gaaaaataac gcagacgact gttccgataa cgttgaaggc aacatgagct
    22321 cctgctaccc gtttagctgc aatattagcc cctaaagagg caatgatggc tgtaatggtt
    22381 gtcccgatat tgtcaccaaa tagaactggc aaagctccct gtaggtcaat tagattgccg
    22441 gcgtagaggt tttgtaaaat cccaatggta gccgaagaag cttgaattag caaggtcaag
    22501 ccagtaccga caaagacacc caaaacagga ttcttactta gctcaatcat atagtcctta
    22561 aagacctgta aatccttgag tggagccatt gcgccgctca tgagattgag ggcaaaaaag
    22621 ataccaccga taccaaagag gatgcgtccg atattattga ctgtccgatt ttttgtaaaa
    22681 aagagacaga cggcaccgat aaagagcata ggtagggcat agttacctaa tttaaaaccg
    22741 atgagaaagg atgtgacagt tgtcccaata ttagcaccca tgacaatccc gatagcctga
    22801 cgtaaggtta agagaccggc actgaccagg ccgactgtaa taactgttac accagaacta
    22861 gactgaatta gagcagtcat cccaatacca accagaactc caaagaaagg attactagta
    22921 tatttgtcaa tgtaaaaacg aaggcgatct ccagcagctt gttgtaaacc gtctcccatg
    22981 gtcttgatgc tatataagaa tagccccaga ccacctaaaa agtgaaataa aatttcctgc
    23041 caattaatgg acatttcttt ttcctccgaa aaataatcgc ggaatatctc ctattctatt
    23101 ttaaaggata aaagtaaatc taacaagtgt taatgtcaag tttgtaaaag aaaattataa
    23161 ttgataagtg tattattttt aagagttttt aaccttattt tagatttgtg aaaacagcta
    23221 ttgttttttg tctaaaaatg ttttaggata aaaatgtgat tatcatgatt ctagagttaa
    23281 aaaactacag aatataaagc gctttcttga aaacaacaaa atcaatcttt taggaggaga
    23341 aaatgaagaa tccatttttt gaaagacgtt gtcgttacag tattcgtaag ttatcagtag
    23401 gagcctgctc gctgatgatt ggtgctgttt tatttgctgg tccagccttg gctgaagaaa
    23461 ctgcagttcc tgaaaatagc ggagctaata cagagcttgt ttcaggagag agtgagcatt
    23521 cgaccaatga agctgataag cagaatgaag gggaacatac tagagaaaac aagctagaaa
    23581 aggcagaagg agtagcgaca gcatctgaaa ctgcagaagc agctagcgca gctaaaccag
    23641 aggaaaaagc aagtgaggtg gttgcagaaa caccatctgc agaagcaaaa cctaagtctg
    23701 acaaggaaac agaagcaaag cccgaagcaa ctaaccaagg ggatgagtct aagccagcag
    23761 ccgaagctaa taagactgaa aaagaagtcc agccagatgt ccctaaaaat acagaaaaaa
    23821 cattaaaacc aaaggaaatc aaatttaatt cttgggaaga attgttaaaa tgggaaccag
    23881 gtgctcgtga agatgatgct attaaccgcg gatctgttgt cctcgcttca cgtcggacag
    23941 gtcatttagt caatgaaaaa gctagcaagg aagcaaaagt tcaagcctta tcaaacacca
    24001 attctaaagc aaaagaccat gcttctgttg gtggagaaga gttcaaggcc tatgcttttg
    24061 actattggca atatctagat tcaatggtct tctgggaagg tctcgtacca actcctgacg
    24121 ttattgatgc aggtcaccgt aacggggttc ctgtatacgg tacactcttc ttcaactggt
    24181 ctaatagtat tgcagatcaa gaaagatttg ctgaagcttt gaagcaagac gcagatggta
    24241 gcttcccaat tgcccgtaaa ttggtagaca tggccaagta ttatggctat gatggctatt
    24301 tcatcaacca agaaacaact ggagatttgg ttaaacctct tggagaaaag atgcgccagt
    24361 ttatgctcta tagcaaggaa tatgctgcta aggtaaacca tccaatcaag tattcttggt
    24421 acgatgccat gacctataac tatggacgtt accatcaaga tggtttggga gaatacaact
    24481 accaattcat gcaaccagaa ggagataagg ttccggcaga taacttcttt gctaacttta
    24541 actgggataa ggctaaaaat gattacacta ttgcaactgc caactggatt ggtcgtaatc
    24601 cttatgatgt atttgcaggt ttggaattgc aacagggtgg ttcctacaag acaaaggtta
    24661 agtggaatga cattttagac gaaaatggga aattgcgcct ttctcttggt ttatttgccc
    24721 cagataccat tacaagttta ggaaaaactg gtgaagatta tcataaaaat gaagatatct
    24781 tctttacagg ttatcaagga gaccccactg gccaaaaacc aggtgacaaa gattggtatg
    24841 gtattgctaa cctagttgcg gaccgtacgc cagcggtagg taatactttt actacttctt
    24901 ttaatacagg tcatggtaaa aaatggttcg tagatggtaa ggtttctaag gattctgagt
    24961 ggaattatcg ttcagtatca ggtgttcttc caacatggcg ctggtggcag acttcaacag
    25021 gggaaaaact tcgtgcagaa tatgatttta cagatgccta taatggcgga aattccctta
    25081 aattctctgg tgatgtagcc ggtaagacag atcaggatgt gagactttat tctactaagt
    25141 tagaagtaac tgagaagacc aaacttcgtg ttgcccacaa gggaggaaaa ggttctaaag
    25201 tttatatggc attctctaca actccagact acaaattcga tgatgcagat gcatggaaag
    25261 agctaaccct ttctgacaac tggacaaatg aagaatttga tcttagctca ctagcgggta
    25321 aaaccatcta tgcagtcaaa ctatttttcg agcatgaagg tgctgtaaaa gattatcagt
    25381 ttaacctagg acaattaact atctcggaca atcaccaaga gccacaatcg ccgacaagct
    25441 tttctgtagt gaaacaatct cttaaaaatg cccaagaagc ggaagcagtt gtgcaattta
    25501 aaggcaacaa ggatgcagat ttctatgaag tttatgaaaa agatggagac agctggaaat
    25561 tactaactgg ctcatcttct acaactattt atctaccaaa agttagccgc tcagcaagtg
    25621 ctcagggtac aactcaagaa ctgaaggttg tagcagtcgg taaaaatgga gttcgttcag
    25681 aagctgcaac cacaaccttt gattggggta tgactgtaaa agataccagc ctaccaaaac
    25741 cactagctga aaatatcgtt ccaggtgcaa cagttattga tagtactttc cctaagactg
    25801 aaggtggaga aggtattgaa ggtatgttga acggtaccat tactagcttg tcagataaat
    25861 ggtcttcagc tcagttgagt ggtagtgtgg atattcgttt gaccaagcca cgtaccgttg
    25921 ttagatgggt catggatcat gcaggagctg gtggtgagtc tgttaacgat ggcttgatga
    25981 acactaaaga ctttgacctt tattataaag atgcagatgg tgagtggaag ctagctaagg
    26041 aagtccgtgg taacaaagca cacgtgacag atatcactct tgataaacca atcactgctc
    26101 aagactggcg cttgaatgtt gtcacttctg acaatggaac tccatggaag gctattcgta
    26161 tctataactg gaaaatgtat gaaaagcttg atactgagag tgtcaatatt ccgatggcca
    26221 aggctgcagc ccgttctcta ggcaataaca aggtacaagt tggctttgca gatgtaccgg
    26281 ctggagcaac tattaccgtt tatgataatc caaattctca aactccgctc gcaaccttga
    26341 agagcgaagt tggaggagac ctagcaagtg caccattgga tttgacaaat caatctggtc
    26401 ttctttatta tcgtacccag ttgccaggca aggaaattag taatgtccta gcagtttccg
    26461 ttccaaaaga tgacagaaga atcaagtcag tcagcctaga aacaggacct aagaaaacaa
    26521 gctacgccga aggggaggat ttggacctta gaggtggtgt tcttcgagtt cagtatgaag
    26581 gaggaactga ggacgaactc attcgcctaa ctcacgcagg tgtatcagta tcaggttttg
    26641 atacgcatca taagggagaa cagaatctta ctctccaata tttgggacaa ccagtaaatg
    26701 ctaatttgtc agtgactgtc actggccaag atgaagcaag tccgaaaact attttgggaa
    26761 ttgaagtaag tcaggaaccg aaaaaagatt acctagttgg tgatagctta gacttgtctg
    26821 aaggacgctt tgcagtggct tatagcaatg acaccatgga agaacattcc tttactgatg
    26881 agggagttga aatttctggt tacgatgctc aaaagactgg tcgtcaaacc ttgacgcttc
    26941 gttaccaagg tcatgaagtc aactttgatg ttttggtatc tccaaaagca gcattgaacg
    27001 atgagtacct caaacaaaaa ttagcagaag ttgaagctgc taagaacaag gtggtctata
    27061 actttgcttc accagaagta aaagaagctt tcttgaaagc aattgaagcg gccgaacaag
    27121 tgttgaaaga ccatgaaact agcacccaag atcaagtcaa tgaccgactt aataaattga
    27181 cagaagctca taaagctctg aatggtcaag agaaatttaa ggaagaaaag acagagcttg
    27241 atcgtttaac aggtgaggtt caagaactct tggctgccaa accaaaccat ccttcaggtt
    27301 ctgccctagc tccgcttctt gagaaaaaca aggccttggt tgaaaaagta gatttgagtc
    27361 cagaagagct tgcaacagcg aaacagagtc taaaagatct ggttgcttta ttgaaagaag
    27421 acaagccagc agtcttttct gatagtaaaa caggtgttga agtacacttc tcaaataaag
    27481 agaagactgt catcaagggt ttgaaagtag agcgtgttca agcaagtgct gaagagaaga
    27541 aatactttgc tggagaagat gctcatgtct ttgaaataga aggtttggat gaaaaaggtc
    27601 aagatgttga tctctcttac gcttctattg tgaaaatccc aattgaaaaa gataagaaag
    27661 ttaagaaagt atttttctta cctgaaggca aagaggcagt agaattggct tttgaacaaa
    27721 cggatagtca tgttatcttt acagcaccac actttactca ttatgccttt gtttatgaat
    27781 ctgctgaaaa accacaacct gctaaaccag caccacaaaa caaagtcctt ccaaaaccta
    27841 cttatcaacc ggcttctgat caacaaaagg ctcctaaatt ggaagttcaa gaggaaaagg
    27901 ttgcctttca tcgtcaagag catgaaaata ctgagatgct agttggggaa caacgagtca
    27961 tcatacaggg acgagatgga ctgttaagac atgtctttga agttgatgaa aacggtcagc
    28021 gtcgtcttcg ttcaacagaa gtcatccaag aagcgattcc agaaattgtt gaaattggaa
    28081 caaaagtaaa aacagtacca gcagtagtag ctacacagga aaaaccagct caaaatacag
    28141 cagttaaatc agaagaagca agcaaacaat tgccaaatac aggaacagct gatgctaatg
    28201 aagccctaat agcaggctta gccagccttg gtcttgctag tttagccttg accttgagac
    28261 ggaaaagaga agataaagat taaatatcga aaaatcttgt gaaatctttc cttatatttc
    28321 caaagtgtga tataatagtt tcgaataaaa taaataaagg agtttttgta acatggcaaa
    28381 acttactgtt aaagacgttg acttgaaagg taaaaaagtc ctcgttcgtg ttgacttcaa
    28441 cgtaccattg aaagatggcg taatcactaa cgataaccgt atcacagcag ctcttccaac
    28501 tattaagtac atcatcgaac aaggtggacg tgcaattctt ttctctcacc ttggacgtgt
    28561 gaaagaagaa gctgataaag ctggtaaatc acttgctcct gtagcagctg acttggcagc
    28621 aaaacttggt caagatgttg ttttcccagg tgtcactcgt ggtgctgaat tggaagcggc
    28681 aatcaacgct cttgaagatg gacaagttct cttggttgaa aacactcgtt acgaagatgt
    28741 tgacggcaag aaagaatcta aaaacgatcc tgaacttggt aaatactggg catcacttgg
    28801 agatggtatc ttcgtaaacg atgcattcgg tacagctcac cgtgcacacg catctaacgt
    28861 tggtatctca gcaaacgttg aaaaagcagt tgctggtttc cttcttgaaa acgaaattgc
    28921 ctacatccaa gaagcagttg aaactccaga acgtccattc gtggctatcc ttggtggttc
    28981 aaaagtttca gacaagatcg gtgttatcga aaacttgctt gaaaaagctg ataaagtcct
    29041 tatcggtggt gggatgactt acacattcca caaagcacaa ggtatcgaaa tcggtaactc
    29101 acttgtagaa gaagacaaat tggatgttgc gaaagctctt cttgaaaaag caaatggtaa
    29161 attgatcttg ccagttgact caaaagaagc taacgcattt gctggttaca ctgaagtgcg
    29221 tgacactgaa ggtgaagcag tttctgaagg cttccttggt cttgacatcg gtccaaaatc
    29281 tatcgccaaa tttgacgaag ctttgactgg tgccaaaaca gttgtatgga acggacctat
    29341 gggtgtattt gaaaacccag atttccaagc tggtacaatc ggtgtgatgg acgctatcgt
    29401 gaaacaacca ggagttaaat caatcatcgg tggtggtgac tcagctgccg cagcgattaa
    29461 ccttggccgt gcagacaagt tctcatggat tagtacgggt ggtggagcat caatggaact
    29521 tcttgaaggt aaggttcttc caggacttgc agccttgaca gaaaaataag attttataaa
    29581 caaatcaaag aagagaggga tgaaagttcc tcttttcttt tgcttaaaat aaaaacgctt
    29641 cctctcaact attactcata aaaatcaccg atttatgata aaatggaaat agaaagttga
    29701 gattatgagt tattttaaaa aatataaatt cgataaatcc cagttcaaac ttggtatgcg
    29761 aacctttaaa acaggtattg ctgtttttct agttctcttg atttttggct tttttggctg
    29821 gaaaggtctt caaattggtg ctttgacagc cgtttttagc ctgagggaga gttttgatga
    29881 gagtgttcat tttgggactt cgcgtattct aggaaatagt atcggtggac tctatgcctt
    29941 ggtcttcttc ttattaaata cttttttcca cgaagccttt tgggtgacct tggtagttgt
    30001 tccaatctgc accatgttaa ccattatgac aaatgtagcc atgaataaca aagcaggggt
    30061 tattggtggt gtagcagcta tgttaatcat taccctatca attccaagtg gtgagacaat
    30121 tttgtacgtg tttgtgcgtg tattagaaac gtttatggga gtttttgtcg caattatcgt
    30181 aaattacgat attgatcgta ttcgtctctt tttagagaaa aaagaaaaat aatgttacat
    30241 tttataacat tatcaattga cgtttgtctt tttttagact ataatagaca gaaagaagga
    30301 aattgtaaat gaaggaaaaa gaatttcgcc gaaatatggc tgtttttcct atcggcagtg
    30361 ttatgaagtt gaccgattta tcggcgcgtc agattcgtta ttatgaagat caagagttga
    30421 tcaagcccga tcgaaacgaa ggaaatcgtc gcatgtattc cttgaatgac atggatcgtc
    30481 tgcttgaaat caaagattat atctctgaag gttataatat cgctgccatt aagaaaaaat
    30541 atgctgaacg tgaagcgaaa tccaagaaag cggttagtca gactgaagta cgtcgtgcac
    30601 ttcacaatga actcctccaa caggggcgtt ttgcttcagt acagtcacct tttggtcgcg
    30661 gttaggcaac cgcaagtagt catagattaa ggagaaaact tatgccaatc acagctgcag
    30721 atattcgtcg tgaagtcaag gaaaaaaatg ttacctttat tcgtcttatg ttctcagata
    30781 ttttgggaac catgaaaaac gtcgaaattc ctgctacaga tgaacagtta gataaggtct
    30841 tgtcgaacaa ggttatgttt gatggatctt ctattgaagg ttttgtacgt atcaatgagt
    30901 cggatatgta cttgtacccg gacttggata catggacagt cttcccttgg ggagatgaaa
    30961 atggaagtgt tgcaggtctg atctgtgatg tttatacaac agaaggtgaa ccatttgcgg
    31021 gtgaccctcg tggtaatttg aaacgagctc ttcgtcacat ggaagaagtt ggattcaaat
    31081 ccttcaacct tggtccagag ccagaattct tcctatttaa gttggatgaa aatggggacc
    31141 caacacttga agtgaatgac aagggtggct actttgattt ggcacctact gaccttgcgg
    31201 acaacacacg tcgtgagatt gtgaatgtct tgaccaaaat gggatttgaa gtagaagcga
    31261 gtcaccacga ggttgcggtt ggacagcatg agattgactt taagtacgat gaagttctcc
    31321 gtgcttgtga taagattcaa atctttaaac ttgttgttaa aaccattgct cgcaaacacg
    31381 gactttacgc aacatttatg gcgaagccaa aatttggtat tgctggctca ggtatgcact
    31441 gtaatatgtc cttgtttgat gcagaaggaa ataacgcctt ctttgatcca aatgatccaa
    31501 aaggaatgca gttgtcagaa acagcttacc atttcctagg cggtttgatc aagcatgctt
    31561 acaactatac tgccatcatg aacccaacag ttaactcata caaacgtttg gttccaggtt
    31621 atgaagcgcc tgtttacatt gcttgggctg gtcgtaaccg ttcgccactt gtgcgcgtac
    31681 ctgcttcacg tggtatggga actcgtcttg agttgcgttc agtggatcca atggcgaacc
    31741 cttacgttgc tatggctgtt cttttggaag ttggtttgta tggtattgaa aataaaatcg
    31801 aagcaccagc tcctatcgaa gaaaatatct acatcatgac agcagaagag cgcaaggaag
    31861 ctggtattac agaccttcca tcaactcttc acaacgcttt gaaagctttg acagaagatg
    31921 aagtggttaa agctgctctc ggagatcaca tctacactag cttccttgaa gccaaacgaa
    31981 tcgaatgggc aagttatgca accttcgttt cacaatggga aattgataat tatttagacc
    32041 tttactaata ctaatataga agaaagattg cctgtgggta aacagtcaca cagcagtcta
    32101 agccatcaaa tacctataac ccttaaaata gcgatttcgg tcgctattta tttttcgaaa
    32161 aatcctcttg actcttttgc gaattagatt tatcatcaga cgtgtagaag aaaatcaagg
    32221 agtcactatg gaaaaattca atttcaaaaa caatatcggg caagaaaaca agttacttca
    32281 aatcgaaatc tacaagttta ctaactttta caagcttcaa aattacacat ctgtaaatat
    32341 tttttcgaaa gatatatttg aagccatagt aaattgagac tagaatagta cactacatct
    32401 gctaaaaatt tctagaaact aatttaactt tcctaatcga tttgtttaca tcttatttca
    32461 atctactata ttatctcaat aaatgatgat ggcgactgtt ttgtttgtgc ttgtcgattt
    32521 ttgaatccct gatcgagcgg aagaatattt ctgccgaggt tgccaagggg aaaatactga
    32581 agatattgaa ttttatgatg aacaattaca ggcagaaaag gtggaggttt tgaatattcg
    32641 attggaagta aaaaattgaa ttatctacaa tctcatcaac aataaaccta tttcaacccc
    32701 attatctata ggcgtatttt tacgcctttt tatatacttg aagcacata
//
LOCUS       DAVHSY010000020        32648 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.020, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000020 DAVHSY010000000
VERSION     DAVHSY010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32648
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.020"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(361..1050)
                     /gene="rplA"
                     /locus_tag="VVR43_001168"
     CDS             complement(361..1050)
                     /gene="rplA"
                     /locus_tag="VVR43_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU6149533.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKVKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1258..1683)
                     /gene="rplK"
                     /locus_tag="VVR43_001169"
     CDS             complement(1258..1683)
                     /gene="rplK"
                     /locus_tag="VVR43_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU6149534.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(1806..2522)
                     /locus_tag="VVR43_001170"
     CDS             complement(1806..2522)
                     /locus_tag="VVR43_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEU6149535.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2540..3001)
                     /locus_tag="VVR43_001171"
     CDS             complement(2540..3001)
                     /locus_tag="VVR43_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU6149536.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDYQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(3003..4040)
                     /locus_tag="VVR43_001172"
     CDS             complement(3003..4040)
                     /locus_tag="VVR43_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU6149537.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSEAVS"
     gene            complement(4138..5463)
                     /gene="brnQ"
                     /locus_tag="VVR43_001173"
     CDS             complement(4138..5463)
                     /gene="brnQ"
                     /locus_tag="VVR43_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU6149538.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRVLTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5634..5726)
                     /locus_tag="VVR43_001174"
     CDS             complement(5634..5726)
                     /locus_tag="VVR43_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU6149539.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(5769..5921)
                     /locus_tag="VVR43_001175"
     CDS             complement(5769..5921)
                     /locus_tag="VVR43_001175"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU6149540.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLECAHNLPLSQ
                     LADSYD"
     gene            complement(6081..6659)
                     /locus_tag="VVR43_001176"
     CDS             complement(6081..6659)
                     /locus_tag="VVR43_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU6149541.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6713..8113)
                     /gene="pepV"
                     /locus_tag="VVR43_001177"
     CDS             complement(6713..8113)
                     /gene="pepV"
                     /locus_tag="VVR43_001177"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU6149542.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGFKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8126..8731)
                     /locus_tag="VVR43_001178"
     CDS             complement(8126..8731)
                     /locus_tag="VVR43_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU6149543.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            8902..9702
                     /locus_tag="VVR43_001179"
     CDS             8902..9702
                     /locus_tag="VVR43_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6149544.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(9886..10719)
                     /locus_tag="VVR43_001180"
                     /pseudo
     CDS             complement(9886..10719)
                     /locus_tag="VVR43_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
     gene            complement(10709..12556)
                     /gene="uvrC"
                     /locus_tag="VVR43_001181"
     CDS             complement(10709..12556)
                     /gene="uvrC"
                     /locus_tag="VVR43_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU6149545.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEIYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12596..13297)
                     /locus_tag="VVR43_001182"
     CDS             complement(12596..13297)
                     /locus_tag="VVR43_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU6149546.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13376..14608)
                     /gene="murN"
                     /locus_tag="VVR43_001183"
     CDS             complement(13376..14608)
                     /gene="murN"
                     /locus_tag="VVR43_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU6149547.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14613..15833)
                     /gene="murM"
                     /locus_tag="VVR43_001184"
     CDS             complement(14613..15833)
                     /gene="murM"
                     /locus_tag="VVR43_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU6149548.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(15945..16724)
                     /locus_tag="VVR43_001185"
     CDS             complement(15945..16724)
                     /locus_tag="VVR43_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU6149549.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYMALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16793..18454)
                     /locus_tag="VVR43_001186"
     CDS             complement(16793..18454)
                     /locus_tag="VVR43_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU6149550.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18629..20851)
                     /gene="recJ"
                     /locus_tag="VVR43_001187"
     CDS             complement(18629..20851)
                     /gene="recJ"
                     /locus_tag="VVR43_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU6149551.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEERENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21128..21886
                     /locus_tag="VVR43_001188"
     CDS             21128..21886
                     /locus_tag="VVR43_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6149552.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            21926..22690
                     /locus_tag="VVR43_001189"
     CDS             21926..22690
                     /locus_tag="VVR43_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU6149553.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNSKTIGVAQGSITQCLITELGKKKGLTFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22703..23380
                     /locus_tag="VVR43_001190"
     CDS             22703..23380
                     /locus_tag="VVR43_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6149554.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGFFILAMVLGIFFGA
                     MSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23390..24049
                     /locus_tag="VVR43_001191"
     CDS             23390..24049
                     /locus_tag="VVR43_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6149555.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVHNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYKAGMSQGFTSAQILYYIILPQASRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24344..25534
                     /locus_tag="VVR43_001192"
     CDS             24344..25534
                     /locus_tag="VVR43_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU6149556.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLCRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(25855..26736)
                     /locus_tag="VVR43_001193"
     CDS             complement(25855..26736)
                     /locus_tag="VVR43_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU6149557.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(26877..28205)
                     /gene="vncS"
                     /locus_tag="VVR43_001194"
     CDS             complement(26877..28205)
                     /gene="vncS"
                     /locus_tag="VVR43_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU6149558.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTKNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIAFPKVVQD"
     gene            complement(28202..28858)
                     /gene="vncR"
                     /locus_tag="VVR43_001195"
     CDS             complement(28202..28858)
                     /gene="vncR"
                     /locus_tag="VVR43_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU6149559.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCIFTVRNVGYKLERK
                     "
     gene            complement(28907..28990)
                     /gene="pep27"
                     /locus_tag="VVR43_001196"
     CDS             complement(28907..28990)
                     /gene="pep27"
                     /locus_tag="VVR43_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU6149560.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(29169..30548)
                     /gene="vex3"
                     /locus_tag="VVR43_001197"
     CDS             complement(29169..30548)
                     /gene="vex3"
                     /locus_tag="VVR43_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU6149561.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30600..31247)
                     /gene="vex2"
                     /locus_tag="VVR43_001198"
     CDS             complement(30600..31247)
                     /gene="vex2"
                     /locus_tag="VVR43_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU6149562.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31260..32537)
                     /locus_tag="VVR43_001199"
     CDS             complement(31260..32537)
                     /locus_tag="VVR43_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6149563.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYDSSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9226 a         7485 c         6070 g         9867 t
ORIGIN      
        1 attgaaacta gaatagtaca cctctacttc taaaacattg ttagaaatcg atttgactgt
       61 cctgaacgat tcgtcctatt cttatttcat tttattataa ttgatagtgg tcgccccagc
      121 cagatacctt atccgctata taggccttat tatcacgttc ctgttcgtag agccacgatt
      181 tcgctatccc ttcctctgac gattcttatt tccagcgtca gacttgggaa tcgctattgg
      241 gttcaccggt agtaggtgcc caccgaggac ttacacctca gatatacgac atgcccgtcg
      301 tacatcaaaa aaagttgaga catagtgtct tcaacttttt tacattactt taactactga
      361 ttaaagtgag tttacgtcaa ctttgatacc aacaccttga gtagttgtga tagtcaagtt
      421 tgttacgtaa gttcctttag ctgtagctgg ttttactttt tggattgttt cgttgaaagc
      481 tttaaagttt tcaaccaatt tttcagcttc aaatgatact ttaccgatga ttgcttgaac
      541 gttacctgca cggtcagcac ggtaagtgat tttaccacct ttagactctt caactgcttt
      601 agcaacatcc attgttacag taccagtttt agggtttggc atcaagttac gtggtccaag
      661 gacacgtcca agacgtccaa caagagccat catatcaggt gtagcgataa ctacgtcgaa
      721 gtccaaccaa ccgtcgttga ttttagcaac aaggtcatct tcaccaacaa agtctgcacc
      781 agcagctttt gcttcttcag cttttgcacc acgtgcgaaa acaagaacac gtgaagtttt
      841 accagtaccg tttggcaata ccattgctcc acggatttgt tggtcagctt ttttaacgtc
      901 gatgttcaag ttgtaagcaa cttctacagt tgcatcaaat tttgcaaagt tagtttcttt
      961 tgcaagtgct acagcttctt ctacactgta tgcttttgtg ctgtcgattt tctcaagagc
     1021 agcacgaagt tgtttgcttt ttttagccat tttctattct ccttgtaagt ggttcaatcg
     1081 attttcatct cccacgtcac ttctcgaaat gatgaagtct tgcgggtttt cagtctacta
     1141 tttttctctt cctacggcct taagctccct tgctgtatcc aagtacaagc ctcagtcact
     1201 tgcctagtat gaaaagcaac taatagactg ctgtgagatt ttctactgtg ttattgatta
     1261 gtcaacaaca gtgaatccca tagaacgagc agtaccttcg atcatacgca ttgcagactc
     1321 tacgtttgct gcgttcaaat ctggcatctt agtttctgca atttcttgta cttgtgcacg
     1381 agtaactgta gcaactttag ttttattagg tgtacctgat cctttttcaa cacctgcagc
     1441 ttttttcaaa agaacagcag ctggtggtgt tttcgtaacg aaagtaaatg atttatcttc
     1501 gtaaactgag ataacaactg gaatgatcat accagcttgg tcagctgtac gagcgttgaa
     1561 ctcttttgtg aatcccatga tgttgatacc agcttgacca agagcaggtc caaccggtgg
     1621 agctggtgta gctttaccag cagggatttg caattttaca agtttttcga cttttttagc
     1681 catttttaaa tcctcctttg tggttttggc ggtaattaga gatttttacc tcccacaagt
     1741 atgctttaca catacctttc cattatacac tatttatcta aaaatgcaag agaaaacttt
     1801 catttttaat cgacataatc gccgccttca aagccatagt actcttccaa actgagacca
     1861 cttgcagcaa tttctttggc ttcttttcca acgtagcgga gatgccattc ttctgccatg
     1921 tagccagtct ccttttcctt gcctttaaga tagcgaacaa caaagccata gtcagccgca
     1981 tggtccaaga gccactgggc tgccttttct tcagtaacta aatccccatc tgtcccaatc
     2041 aaatcaaaag caagacccgt ctggtgttca ctgtaacctg ggcgtgctga gtagcgatct
     2101 gctgcttcct taccatcttg attgacatag tcttggtaga gcttagcctg agtttcataa
     2161 ctcctaaacc cactgtattg gtcactgatt ggatagccct cagcctgcat agctgcgatt
     2221 agtttgagca actctgcctt ggctgttgga ttttctcctg gattgtaatc ttttgacaaa
     2281 ggataacgtt tattagctag gataatctca tcgtatttcc cttggatact ataatagctc
     2341 cctttattgc taacttctgc ctttttctga ctagaagctt gagatttgct acctacagtt
     2401 ccttccggtt gactgctttg ctccgttttt tgagtgtttt cttcaacttt ggttttttct
     2461 tgcgaacaag ctgcaagggt caatgctagt aaaccagata aaatgacata tctttttttc
     2521 atttctttct tcctctctct taggccaaat acttctccaa ttcatgagat aagattttaa
     2581 tcatctcttc cagctctggc gattgtactt ggcaatcttc tgccgccatt tcttcccagg
     2641 gcacccacca gactgggcca cggccattca aaccgtgact cttcatatca cctgctcttc
     2701 ggggaaaaag atgccaatga gcgtgggcat cgccatttcc taggagttca atattcatct
     2761 tttcagcctc aaatgctttg gcgactgctt cttggactaa actcatttcc tctaaaaagc
     2821 gaagttttac agaagtttcc atatgatgga gttctgtgac atgatctttt gctaaaaata
     2881 aggtatagcc cttaaagtat tggtagtcac caataacaac atagcctgtt tctagttctt
     2941 ttacaaagta gggattttgc ccagctttaa tgagttcgat tctctgacag attaagcaca
     3001 ttctatgata ccgcctcgct cttaagataa gcatcaacca tacgctcagt cgctattact
     3061 gaatcgatgt gggtgcgctc ataagagtga ctggactcaa taccagctcc aagaagtgca
     3121 tgcttgacct ctgcacctgc tgacatcgct gctgaagcgt ccgatccgta aaatggatag
     3181 atgtcgagct taaatggaat atcttgctct ttagccaagg caaccaagtg ttgacggaag
     3241 tcatagtgat aaggacctga agcatccttg acacagatag atactgtgta ctcatctgtc
     3301 tgctggtcat ctcccatagc tcccatatcc acagccagat attctactac ctgagcagga
     3361 atgttagaat tagcaccatg tcctacttct tcaaaaactg aaaaagcaaa atgagttgtt
     3421 actggcaatt caatcttctc tttcttataa atacgaagca ggttgagcaa aatcgctgcg
     3481 ctgaccttat catccaaatg acgagacttg ataaaacctg tatcagtcac aacagttcgt
     3541 ggatcgaagc tgataaaatc accgacctca atcccaagag cacgagtttc tttttcattg
     3601 cttactttta catccaaacg cacttccata ttgtcctgcg tgcgttctgc agttcctgca
     3661 tccttgtaga catggcaaga agtttggtgg atgaggatgg ttcctgatac cttttgacct
     3721 gtgctagcca catgaacggt acagttttca ccttcaatca tgttccaagg aaaaccaccg
     3781 atacggtcca atttaagacg accatctggt ttgacagcac gaacaatagc acccagcgta
     3841 tccacatggg cagtcacata gcgatgttgc tcatcatttt gacctttgat ggtcacattg
     3901 acaccaccct tagctgtgcg aactggctgg taaccaaaac cttctagagt cttgactaaa
     3961 taattcgaaa tttcacgagt gaagcccgtt ggcgatgcga tggctgtcag ttctttgata
     4021 tattctactg tttgattcat ttcttcacct ctttcgctac ctattataac acatttatca
     4081 tcggataaaa aaagaaaatc actcctgtag acttggctac aaaagtgatt taagtgatta
     4141 ttccatttca aaaacatcgc tttcttgctt gtttggtaga accaatgaga gcaagattcc
     4201 aacaatggct ggcaccaacc atgggagaga tgccttggca aaaggaagaa cgctaacaag
     4261 atttgcaaga aactcaacct taaacgagct tcctagtacg cttgcaatgg caataactgt
     4321 aaccacagca attgtcaact gcatacctgg ttttgaaagg gcaacaaatt tgttgacaat
     4381 gacaatcata acgatagcaa tcgtgattgg gtacaagata accagtactg gaattgagta
     4441 cttgataatc gcatcaagac ccaaattggc aatagcaaat ccaatcaagg taaaggctgt
     4501 cgcataaacc ttgtagctga tttgtgggaa gcgctcatta aagaactcag ctgttgacac
     4561 aatcaaacca acagtcgttg tgaagcaggt tacggtaacc atagctgcaa ggaagagttg
     4621 agctgttgag ccaaagattt cttgagtggc ttgtgacaag atgtaaacac ctggtgttcc
     4681 acccttcatc gcttcagctg gtactgggaa atgatttcca agaaaaccta aaccgatgta
     4741 aagagcgctg aaggcaaggg caacaacgat accaacaacc caaatagttg aaatgtattc
     4801 tttcttactt gaaaatccaa gttgtttcaa ggtttgaact gcgattacgc taaaggccac
     4861 tgaagcaagg gcgtccaagg tattgtaacc ttctaggaaa cctgtaccaa aggcagaagc
     4921 ttgataagca gctgaagcag cttgaggact tgttccacca tatttgatag ctcccagaac
     4981 gaccaagata acaatcaaaa ttgcaaagac tggcgttaaa acacgtccaa tgcggtctaa
     5041 gatttttgat ggattaagcg aaatcaaata ggctgccgca aaatacagaa ccgtaaatac
     5101 aatcaagcca agtcctttat ttgcatccga caaaaggggg ctaatcccta cttcgtaagc
     5161 tgttgtagca gtacgtgggg tagcaaagaa tggaccgatt gacaagtaaa gaactgagag
     5221 gtaaagagtc gcaaaccaag gcgctatctt cgttgaaatc tcgtagatat atcctttagg
     5281 atttagcgtt ccaataataa gggtcaagac ggcgatacca acgcctgaaa agacaaaacc
     5341 tgcgatggca ggaagaaaat gttctccaga tagagcacct agagaaggcg gaaaaatcaa
     5401 gttccccgca ccaaaaaata ttccaaacag gagcaaacct gttagggtac cttttttagc
     5461 cataaaaatc tccttcatat ttataaaata ctgacctagt ataccacgat taggagtctg
     5521 aaaaaagcat cacgaggcaa atattaaatg ttttcaattt tcttaaaaat aagaattatc
     5581 taaaaataaa actctcctac ccagtccaca ccaagtagga gaaatgcaaa attttaaagt
     5641 tcttcaaagg ctaacatgcc accctggaca ttgataacat tataaccttg ttctaacagg
     5701 aattggcaag cacgcgccga tctcattcca gatttgcaaa taatataatg caagcgatct
     5761 ttgtccaatt aatcataact atcagccaat tgactaagcg gtaggttgtg ggcacattct
     5821 aaatgaagag ctgcaaactc atccacttct ctcacatcca ctagagaaag ctggtcgttt
     5881 tggtaaagct ggtaaaatgc gtcaaaggct atttctttca ttctttttct tctaatactc
     5941 ttcgaaaatc tcttcaaacc acgtcagcgt cgccttaccg tgcgtatgtt accgacttcg
     6001 tcagttttat ctgcaacctc aaagctgtac tttgagcagc ctacgactag cttcctagtt
     6061 tgctctttga ttttcattga ctataaaatg gttttaattc tttttttcaa atctggcact
     6121 acttctgcct caaaccaagg atttttggcc atccagattt gatttcgtgg tgatgggtga
     6181 actagcggaa aataggctgg cagatagtct ttatagtgtt tcaccctctc cgttaccttc
     6241 ccactgattt tctcctgtaa atagtaggct tgggcatatt gcccaatcaa gagggttaac
     6301 tgaatatcag gcaattcctg taagagctgc ggatgccatt tttctgcaaa acctgtacga
     6361 ggcggaagat cacccgactt gccatgtcct ggaaagtaga aatccatagg caaaacagca
     6421 aaataacctg aattgtaaaa ggtatcttca tccacaccta gccagtcccg caagcggtca
     6481 ccacttttat ctttccagta aaggcctgct tcttgagttt taagtcccgg agcctgaccg
     6541 atgatattga tgcgagcagt ttttggcgct gcaaagagag gctcaatgcc acgctctgta
     6601 tagctggcat tctgtgaatc cgccatgata gcctgtttga ttctttcgat ttgagacatc
     6661 tactttccct ccaaaaagaa gtccaagcat aagatctcag acttctatcg ttttatttga
     6721 tcaattcgta aatagcttcg gcatagattg ctgctgctcg gaagagatcg tccaaggcga
     6781 taaattcatt ggcttggtgc atggtatcaa ttgagtctgg gaacatagca ccataggcaa
     6841 ctccgcgctc taacaagcga ccaaaggttc caccaccgat gacttgttca tgacctttaa
     6901 agccagtttg tttttcatag atattcaaca aggtttgcac aagtggatct tccattggca
     6961 catagtgagg cgtgtgaccg tgttcagaca ggctaacaga aacaactggc aagttttcaa
     7021 ggattgactt gatttgttct ggacttgttc cttttggata gcggatgttg agggcaatgg
     7081 tattatcagc acttgtttca tcgaagcgga agacgccggc attcatagaa agagcaccca
     7141 tcttttcatc cacatgagca atcttaagat tttcaccctc atgatcgttc aagagaattt
     7201 tacctgcgat gtcaaggtag tctttggctg gaccagcaaa gccaaactga ctgaggaaga
     7261 gggcaaggta agttgcgcca ttgacacctg aagcaggcat agcaccgtgg gctgatttac
     7321 caatgatcgt caccttgtat ttgccagctt cttcttggag ttctcctcta agtttgtgtt
     7381 ctgcaacaaa ggcatctagt ttagcttgca agtcagccaa gtcacctgaa acgactgctg
     7441 ttgctgattc tggtaccata ttttcacgta aaccacctgt aaagctgtga agacgggcaa
     7501 cacctgtatt ttctcctgca aagtggaggt attccgtgat atttcctttt tcaccattga
     7561 tgattggaaa ttcagcatct ggtgagaaac cgaaatctgg tttggcaagt cctacgtgct
     7621 caaagtagta gtccatgtct gcccagcctg attcttcgtc tgttccaacg atgaagcgaa
     7681 ctttcttaga agttggaaga cccaattctt tgatgatttt caaaccatag taacaagctg
     7741 ttgtaggacc cttatcgtcc gaagccccgc gcgcataaag gcgaccatct ttgatagttg
     7801 gtgtgtaagg gtctgtgtcc caaccgctac cagcaggcac cacatccata tgggcaaaga
     7861 ttccgagaac ttcttctcca tcaccaaact caaaatgtcc tgcatagtta tcaacattct
     7921 tagttgggta gccatcgcgg tctgcgattt caaggaattt ctccaaggct tttactggac
     7981 caggcccaaa tggatgctgg gcatcagcct tgctgtcatc acgttctgaa ttgatttcca
     8041 aaaggctaaa caagtcagcc aagaggtctt ctttgcgttt ttctacttct gctgtaaaat
     8101 caattgctgt cattttttct tctttctatc ttttctcgat gatttcatct actggcaagc
     8161 ggtagcttgg ttccaatttt tcgtctgtat aacccactgt gatcaagagt tctgggcgga
     8221 aacggtcttc gatttccaaa acttcattaa cttttgattt gtcaaaacca agaataatgt
     8281 tagaaccaat tccttggtct gtcaatgcaa gaaccaagtt catggcaacc aaacctgcat
     8341 tgagagctag gtagtcgctg acttgttgtt cattgtagcg tgcaaattca gctggcaaat
     8401 ttttcatgaa gtattgaagt tgttcttctg agaaattgtt agcaccacca actcgggcaa
     8461 tcttacgagc gcgtttggca aggtctgtat ctgtaaatag ggcaatggtt acaggtgctg
     8521 atgatacctg ctcaaagttt gaaccataag ccaactttgc cagttcagca tttttctcac
     8581 gaacaactac aaatttccaa ggctggctgt tgtgggcgct tggcgccaag gttgcaattt
     8641 cgatagccgt acgcacatct tttggatcaa caggcttatc agtgaaatgc ttggtcgcat
     8701 gacgtttttt atttaattca agaaatttca taatcgattt ccttttctaa ttctactgct
     8761 tccattctac cataatttga aagagcttgc agggattttt catgattaag tttttctatc
     8821 acagacataa aagatatata ttggtttatc aggaaagttt ctgataaact agcaagtact
     8881 ttacatttga atggagacag tatgaaaaaa tttagcctat tactagctat cctaccattt
     8941 ttggttgcct gtgggaatca agctacaccc aaagagacta gcgctcaaaa gacaatcgtc
     9001 cttgctacag ctggcgacgt gccaccattt gactacgaag ataaaggcaa tctgacaggc
     9061 ttcgatatcg aagttctaaa ggcagtagat gaaaaactca gcgactacga gattcaattt
     9121 caaagaaccg cctgggaaag tatcttccca ggacttgatt ctggtcacta tcaggctgcg
     9181 gccaataatt tgagttacac aaaagagcgt gctgaaaaat acctttactc gcttccgatt
     9241 tccaacaatc ccctcgtcct tgtcagcaac aagaaaaatc ctttgacttc tcttgaccag
     9301 atcgctggta aaacaacaca agaggatacc ggaacttcta acgctcaatt catcaataac
     9361 tggaatcaga aacacactga taatcccgct acaattaatt tttctggtga ggatattggt
     9421 aaacgaatcc tagaccttgc taacggagag tttgatttcc tagtttttga caaggtatcc
     9481 gttcaaaaga ttatcaagga ccgtggttta gacctctcag tcgttgattt accttctgca
     9541 gatagcccca gcaattatat cattttctca agcgaccaaa aagagtttaa agagcaattt
     9601 gataaagcgc tcaaagaact ctatcaagac ggaacccttg aaaaactcag caatacctat
     9661 ctaggtggtt cttacctccc agatcaatct cagttacaat aacactcttc gaaaatctct
     9721 tcaaaccacg tcagctttat ctgcaacctc aaagctgtgc tttgagcaac ctacggctag
     9781 cttcctagtt tgctctttga ttttcatatt gagtataaga tatattaaaa gcgatgggat
     9841 cagccaatcg cttttttagt ttgcattggt tattttagga aactcttaca aaaaatcaaa
     9901 aaaattcttc acatcctcta catacctatg cttttctatt aagcttgcta atagttccag
     9961 attgtgcctc tgatagttat cttcacgacg tagttcttca tacatttcga taaagggaaa
    10021 acccttggat ttggcaaatt ctaactcagc ctcgtaatca taagcgactt tacgaaatag
    10081 gatatttacc aattccccat cttcaacctc tatcacggca tactgggcac ggtgattttt
    10141 taacgcctcc caattaaaat agggcatgcc aatcgaccct ggattgatga tttgttgccc
    10201 ttgactacca taacgaagca actacttgtg aacatgacca taaactgcca cgtccgtttc
    10261 cgcatctagc agttggtcaa atttctctgt atcattctca actagcaagt caccaccata
    10321 gtttttgtca ggtaaattat gagagataga aaagcgcaat ccgtcaattt ctttcttttc
    10381 cagcaaaggc aagcttcgta gccagacaat cgttgcagga tccattcgct ccatcaaata
    10441 ctgtgtcata cgcaagagct gaacttcctg tgggtcttct aagccatatt gcccatctaa
    10501 agcctcaagg acacaatcat cccaattgcc tcgaacactt gccgtgatag gaagttcctt
    10561 taacagagcg accaagtcat ttgcacctgg accagggagg aaaatgtctc ccatgagcca
    10621 atattcactg gctccttgag ttttagcatc tgcaatcact gcttctagcg ccgtcgcatt
    10681 gccatgaaca tctgataaaa ttgcgatttt atggtttatt gtggtttcct tccgtttggt
    10741 aatctactct ttcttccgcc acttgaagca agatttctgt ttcctgcggg ttcaacttgg
    10801 tttgcacagc ctctgctact gctcttggta ctccaacttc gacaatctca tccacactgg
    10861 cttccttgat tttggtcaga gacttgaagt gcctcatgag attttgcttg cgtttaggtc
    10921 ccagaccatc aatcccatcc aattgagatg agaaagaatt tttggagcgc agttggcggt
    10981 ggaaggtaat ggcaaagcgg tggacctcat cttgaatgcg ttggaggagg aaaaattcct
    11041 gagaattgcg agacaagtcc accacttcca gcggatctcc aaagagcaat tcatgggttt
    11101 ggtgcttatc attcttttgc agacctgcaa ttggaatatc caagcccagt tcttcttgga
    11161 tgacttgctt agcaatattg acttgacctt gccccccatc aatcacaatc aaatctggag
    11221 gagtcaaagc ctcacgctgt actcgaccat agcgtctgcg aatgacctct cgcatactgg
    11281 catagtcgtc tggcccgact acggtcttga ttttatactt acggtaatcc ttcttactag
    11341 gcttgccgtt gacaaagacc accatggctg aaacaggact agttcccatg atgttggagt
    11401 tatcgaagga ctcgatgcga actggggttg ggatttgaag caagcgtcct agattttcaa
    11461 tagctccttg ggtcttctcg acagatttct ctagcaggtt gaacttctgc tctaggctaa
    11521 cacgggcatt ttttatagct aaattgacca gctgcttttt ctctccacgt tgaggcttaa
    11581 gaatcttgga atccaccaag gccttgacag cctcttcgtc aatatcttgc ggaatcagta
    11641 cctcattggg aactagatgg gatttttctt gatagaattg tcctacatag gtcaaaaaat
    11701 cctcatctgg atcattgaag taggggaaga gattgacatc gcgctcgatg agcttaccct
    11761 gacggacaaa gaaaacctgc acacacatcc agcccttatc cacatagtag ccaaagacat
    11821 cgcgattttg gagatcctta gccatgaccc gttgcttggt tcgaagcgtt ccaatagcct
    11881 gaatcaggtc acggtattcc gccgcacgtt caaactccat agtctgggct gccgctgcca
    11941 ttttgccctt tagctcatca atgattttgt tatcctgccc tttcagaaaa tcagaaacct
    12001 cctgggccat agacttgaaa taaatctcat ccttcttaca gatggtgtgg gccatgcatt
    12061 gaccgatatg gtaataaaaa cagaccttag agggcgggtt ggtacactta cgaaaaggga
    12121 atatccgatc cagcaaccgc ttgatttcat tggctgcccc cacatcggga tagggtccaa
    12181 aataaagacc tccgtccttt ttgacctgac gagtgataat caagcgtgga tagcgctcat
    12241 tggtgatttt gatgaaagga taggacttgt catccttgag catgatattg tacttgggct
    12301 tgttttcctt gatcaggttg atttctagga gaagtgcctc aatattagac tccgtaacaa
    12361 taaattcaaa atccacaatt tcagacacca gagcctctgt cttggtatca tgacttccac
    12421 gaaaatagga ccgtactcga ttacgcagat ttttagcctt tcctacatag ataatggtgc
    12481 catttttatc cttatgaatg tagcaaccag ggctggtcgg caagagctct agttttgatt
    12541 taatcaagtt gttcatagtt ccattatagc aaaaaaagta gggaaagata gtaccctact
    12601 cactagtctc atatattttt cggaggtttg caacatcctc ttcctggata ccataaaagg
    12661 aacctgctgg ttgcatgaca gacttctcat ctgtatggtc caagccaatc gcatgaccta
    12721 actcatgttc tgccgtatgg acaaggcgtt cataggagta gccatagtat ggattggaca
    12781 aataataatg attcaaccgc accgttacgg acaagaattg ccctgttaag agattagttt
    12841 gactttccgc ctctcctgcc acaggagtgc ctccgtcgtt catctccgta gccgtaatat
    12901 ccgccttact agactcagtc acgagttcaa agttaaaagc accagtttga ttccagttct
    12961 ggattgcttc taaataagcc tcttgaaagc gtgaatccat ctgcggatcc aggtaaatac
    13021 gagcagaggc ctgtgcccac cttccttcag aatgctggtg actatctgtc tggcttaact
    13081 taggcagttg ccctgttttc tcccattggt caatactttg ttgaccaatt tttactgacc
    13141 gttctgcttg ctttagcgct ccttgaaaat ctccgttcag ataccagaga agtccgaaag
    13201 caagcacaca taagagcaca actatccaaa ccagacgcca aaacaaacgc cacacaaaag
    13261 aaaagaaagc ccctatcaaa cgaaaaagcc agcgcatgtc tctccacctt tctagcaaat
    13321 aagaattatt ttactaaaag aagctaaaag aaatctaaat actgactttt tcatcttaac
    13381 gtcctactat ttttttgagt aactggatag ctttgtattt taaaggagat ggatggtaac
    13441 ggaaagtacc tgctttgcgt acaatatagc cattaaaatt ctgtttaaaa cgcaaaacac
    13501 catcacttcc atcaaaaatc ccttgaatgc ctaggaagtt gtatttaggt attccacgtt
    13561 ttatgctttc caacataaca tatttttgaa gcagggcagg ggcatagaac ttattaaact
    13621 cagtgtagga accactaaag agataagtcg tttcctgagg catataaaca aataaactcc
    13681 cagctaaaac aatatcttct tctccatatt tttcaatcaa gtctcgcgct tctgcttttc
    13741 gaacttcaaa cgtttcaaat tgactagaat attctctcag ttgattttgt tttttctcag
    13801 aatgaggatt tttactcaaa tcaagtcgca acttgtccaa gttttcttct agtttacttt
    13861 gttcaccttg caatttgctc atatagtccg aaaaatttaa gcttgctatg agaaactccg
    13921 cttgttctcc aaaagtatca taaaaatgct cataatattc taaactttta tcactatatt
    13981 ctctacgttc agaggtttct tttgttatat tcttaaaaat cgatagttct tcacgtttta
    14041 actttttcaa ccgaatgcca aaggtttcag cctttttcac caagggttta ccctttttgc
    14101 taaaactttt aagcaaactc ttttcagtta attcagttaa atctttatag tataaccaat
    14161 ctggttctcc acctgggtaa cctgttgtta agccatcaaa ttgataacct aaatcagtca
    14221 aaccttgaat aatacttttt ttctcagcat ctattggatt accttggcta tcaaaagttt
    14281 gataagtttc ataaggtttt acaagcaact ctaatacacc attttgcttg gcatattctt
    14341 ttaactctgc ataaaaaact ggaagagcat cttgttgggt ataaattggc cccgaattga
    14401 gttccatatg cagaccaccc agcatgggca agctataaac cagagctgca acttgaattt
    14461 ctccttcttg tttcaaagca agataaacaa ttcgagcccc tcttttttct agcaaatccc
    14521 ccatctggac agattgcata aaggaacgag aagaaacctg atcagaataa gtctgaaact
    14581 cttctttcgt gagtgttgtt agtgccatat acttactttc tatgtttttt tcttaatgtt
    14641 ttacggaaat caagagcaag tcttaacaga ggatagagag gatgagtggg cattgtaaat
    14701 tcacccaagt attcttcaat cgttggatta aatttttcct taaaatgata aagtccacca
    14761 ttgagagagt tttcaacacc acctaaattt tgccagacca tacctcgctc aaaggcatag
    14821 cgagccgttt cataccatgt taaaattggt gcattgtaac gtttaaaatc atcatccata
    14881 ccagcatata tattaacaga ggtagtacca aattccaaac tcaaagtagc cgctaaagga
    14941 actctcgctt gacctacatc tatatattcc tgcaagaagg tcaattcctc taacaaacgt
    15001 tctttttcct tcttctgcgc ttctactttt gaagttcgag tcgactcagt aaaggtctct
    15061 tccaaggctc tatttttcgc taactgttct tctaattctt gcgaacgttt agaaacatcc
    15121 aaggtggcca aggtgatata ggccttgtcc ttaaaattat ctaacaattt tttataatag
    15181 gcttcattcc tcaaatgaat ctcttttcgc ttctcagttt ttttcatcaa ctccgaaaat
    15241 gaatctaata gttccagtcc accatattga atctcaagcc ctttgtttcg tgctgttcga
    15301 atagcctgtt ttgttgactt ggaaagttta tcttcttcaa aattttcctt gtatattttc
    15361 gcctgaatac gaggttgaat ggtgtctccc atttcctccg tttttcctga ccaccttact
    15421 cccatttgtt gcaaactatc aataatagcc agattttcag gaaattctgt cttttcctga
    15481 ttgattaaac tttgagatag gcaaatactt gggtcaaaag tcacaaaaac cgctctctta
    15541 ctgcgagcat aggacttaat agactgaatg gcaaaattca agagttcttt atccccataa
    15601 tccaatatag gtcctcttgg gatgtaaaac attttatagc ctagcggaag agttctaatc
    15661 aaaatactag ctgtcgccag taatttttct tccctgtaaa caccaaactt ctcatgttgc
    15721 caattagact taacttcctc ccaagcacta ctttgtaata cattggctaa ttcatgttct
    15781 ttgacaaact gatcatattc taatgtggga atgccaattt gataacggta catttcctac
    15841 tctctttctt ccagtatttt attactattc tactactttc gtttgaaaag tctagtgaaa
    15901 acatatttta ttttagttct actcccccta tgctgaagtt caaactaagt cagtctctct
    15961 tctaatttga aatcaattgg tagggttgtt aaaaaaactt ccaattgttt ttcccagtag
    16021 taccactcgt gagttccagc actatggcta taggtcacat caaaacctag ttttttgaga
    16081 tttttcactg cgagattatt ggcttcgtac aagaaatcct gttcgccaca ccacgcccaa
    16141 agtttggtct ttttatccga ttttttagcc agactttcaa gagaataggg actagttgtc
    16201 cagtctctaa tctctccaaa aacacctctc cagtaggctg gacttcccag attttgactt
    16261 tcaggagaaa agttttgaaa gctgagggca cctgaaaaac tagctgcatg agaaaaacga
    16321 tttgtcgtaa gagccagttt gaagcagccg tagcctccca tagaaagacc agcgataaag
    16381 gtcttttcac gcttgctagt catattaggg aagaagcgtt tcagaacctg tggcaattcc
    16441 tctgctagag ccatgtagta gtcaaaacca tactgggtat cggtgtacca accattgctg
    16501 gtattgggca taacaacgat gagattagtt cctcgaagca agcgttctac attggtccgc
    16561 ttaagccaac tattatgatt tccagacatc ccgtgcaaaa ggtacaagac gggaatatct
    16621 tcacactctg gttcttccac tcgattggca tcagggtaga ggacattcac cccccactcc
    16681 atatccaata cttgtgagta atactcgatt ttcattactg ccatgatttt ctccttctat
    16741 ttttctataa gaaaaagccg aaactcgact ttctctctgt ttatttcaac gattattttg
    16801 cttccatgac tactggtaaa atagctggac gacgcttggt ttggtcaaag agatacttgg
    16861 tcaaattatc tcgaaccttc cctttaagat ctgcccagtc aaagtcatct ccttgaagat
    16921 actcttctac cgtttggtta atcaattctg aactttcacg gagaatatcg cgactcttct
    16981 tgagataaac aaatccgcgc gtatgaacac gagccctagc cacaattttc ttctcacgac
    17041 ggttgactgt aatagccacg atgaaaattc catcctctga caagacctta cggtcacgaa
    17101 gaacaacatt tccaacatca ccaatggcat tcccatcaat caagatatct cctgctgaaa
    17161 ccgatccagc tggaacaaag tctccattct cgtaagccat ggtcgtcccc tttttaggaa
    17221 tgaagatgcg ttctggcaac atcccaactg ccatggcagc cttagcgtga gcatccaact
    17281 cacgatactc cccttggaca gggaagaggt acttaggttg caaaagattg atcatcagct
    17341 gcaaatcacg cacatttccg tgccctgata catgtaaact ttgggtaatc aatttgacaa
    17401 ccccacctgc ctgataaatc atattttcca cacgcgcaac aaaggcttct ttagcaatag
    17461 acggagccgt agcaatatag accaggtccc catccttgat ttctacataa cgatggcgac
    17521 caatcgacat cttacgaagt ccattgatag gttcacccat acgacctgtc tcaagaataa
    17581 tcaactcatg gtcttcaaag cgagacatat ctttaggctt aatcaagaga atttcgttgg
    17641 ctaaagacaa cttcttaaga cgaatcgctg tgcggacgat attttcaata tcaaatcctg
    17701 tcaagacgat acgtcgacct gttttatccg cagcgtcaaa aatctgctga atacgagaaa
    17761 gattactgga aacagctgca acgatgatac gaccttccca gtcagcaata gtttgggtaa
    17821 tttcatccct aacttcactt tcactagcca cctgaatatt gctgtctgca ttggccgaat
    17881 cactgaggag agccaggacg ccgtcacgac caatctctgc caaacgagca aaatcagttg
    17941 cataagattc actagccgtt tggtcaaatt tgaagtcacc tgtataaacg atgcttcctt
    18001 ccgatgtctt caagacaatt cccagactct ctggaacgga gtaagtcgta gggaagaagg
    18061 aaaccactgt cccaccaaaa tcaatctccg tattctcatc aatgacatgg aaatcattaa
    18121 atttcttaac ggcatcattt cctttgacaa agagctttgc caactcaatg gtcaactcag
    18181 acccaaatac aggaacttta gcctctgcca agagataagg tagagcacca atggcatccg
    18241 catgcccgtg ggtcaagaaa accccagcaa tacggtcgct attttcaaaa aggtaatcca
    18301 tgtttggaat caccacatcg acccctaatt gttcattttc aggatatttt aaccctacat
    18361 tcaaaacaaa aatggactct ccaatttcag caatgtacat attttttcca ttctcacgca
    18421 caccaccaag tgttgttaaa ctgatattac tcatttttcc tccaaaatct tagtttatct
    18481 tgattatagg gcaactctac cctcttattc taaaagttct gatactttca gccgaatctt
    18541 ttcctaccat tataccattt ttttgatgat tttcaaaatg aaggtctgtt ttcaaaaaag
    18601 agttgatttc ccaactcttt cctaacttct actctttttc catcaaaaaa tcataaattt
    18661 cttgcaccgt acccagcgcc atcatttctt ggtctttaac ggtttgtttg agattttggt
    18721 aaatttgact ttctcctatc tcccgctttg gcgcctcttt attgactgtc atcacaccat
    18781 cttttatcgt cacaaagcct agttcttcaa atacttgaat catcttgacc agcaagattt
    18841 gttgaatatt aagatatgca gccaaatctt tcagcttgta gcgaatatca aactctggga
    18901 actggtaaat agtcttgtac aatttagcaa actgatctct agtcccataa cctgtcagat
    18961 aataggtctt gtcaatatca tttttgaaat agacagcaga gaaatgctgt tcctgaaaaa
    19021 tggtcttcag ctgagtaata tcctctggaa tgttttttac gacaacagct tcactagccg
    19081 caagatttgg cagttctcca ggaaaatcca agactggaac accttctggc aagactgcat
    19141 tttttccacg aatgttaaaa agttgaacac cttccactcg cgcatccacc atcatcaact
    19201 ggagggcagt ttggccattc cattggttga cagacaattt aaccgctaac tctagattct
    19261 tggtttgaga aaactctgtc gcccatctgc cttgaccaaa ggctaccact tcaaaactcg
    19321 cctcaccctt ggaaattttc agctttagat gggcattacc tgcccccata gtacgagcac
    19381 tttcgacctg aaaattcttg atataaaaaa taggtttctg attatccatt ccaaaaggag
    19441 ctaaacgttc aaaacttttg accgtttcca agctaagtgc ctccaaatcc aactcttcat
    19501 ctaggtttaa cttattcttg ccaccagcat ctgcaccttt ttcacgaaca taatcttcca
    19561 aaacctgaga taaatctgag agttgctcaa cttccagcgt catacccgct gcacctgcat
    19621 gacctccaaa ggcgatgaag aggtctcgat ggggatccag agcttcaaaa atatcgaccg
    19681 cttccacact acgagcactg cccttggcac gaccgtcttc tatattaaga acaatgactg
    19741 tctgtcccaa ttcttccaat aaacgaccag ccacgattcc tagaacccca ggattccagc
    19801 cttccttggc caagacctga accttcttct caggatccac catggtcttg gcttcttcat
    19861 agatagactg aacgatttcc ttgcgctctt cgtttttctg gtgaatcata agggcaatct
    19921 catgcgcttc ctcatcatca aatccagtca acaaatcaat ggcaggattg ggatcatcca
    19981 agcggcccaa ggcattcaaa cgaggagcaa tctggaaacc aaccgtttct tctgttactt
    20041 cgttggcagc aatcccagcc atgtccagca tttcttgcag accaatgcgc tgggtatgac
    20101 ccaacatttc cagaccatat tgaactaaga tacgattttc atccgtcaga ctcaccatat
    20161 ctgcaatagt tccaatagcg accaaatcaa gcaattccac ttgcacttct tctaacaggg
    20221 cacaagccaa cttgaaagca actccacaac cagccaaata tttaaaagga taatccgcat
    20281 ctggatgttc aggatggaca atagcataag catctggcag ggtttcaggc atggaatgat
    20341 ggtctgtcac aatgacatct actcccatag actgagccaa tgcaatagcc tcatgaccag
    20401 caaccccatt gtccaccgtc acaatcaagg aaatcccttc ttgctcgata aagtatttat
    20461 aaacactagc attagggcca tagccatcgg taaaacgatt tggcaggtaa actcggcact
    20521 cagcaccaag ttgttccaaa ctttccttca caatagaagc cgaagtcatg ccatccgcat
    20581 cgtagtctcc ataaacgaga atattttccc tttcttcaat agcctgacga atccgctcca
    20641 ctgccttgtc catatcatgg agcagataag catcatgtaa gtcctccaag gaaggttcta
    20701 aaaacttctt cagactttct tggtcctgaa tccctctctc aaacaataac cgagccacct
    20761 caggacccag tccagccttc ttggctatct ttgtaaaatc cgcatcttct acctgcaggg
    20821 caaactgcca ttcataagta ggtgttatca aaaagacatc cactctttct aagaattcta
    20881 ttgcttcatt ataacatgat ttagacgttt tctctatcca gattgctttt ttataacatt
    20941 ttatagtata ttgaaactag aatagtacac ctctacttct aaaatattgt tagaaatcga
    21001 tttgactgtc ccgatcgatt tttcctgttc ttatttcact atagtgaatt ttttcagata
    21061 cgatttgaca agaacattct tttattgcag aatcgtgtta taaaatctaa cataaaggag
    21121 ttctctcatg gctttagtag aatttaaaaa cgtcgaaaaa tattacggag actaccacgc
    21181 actccgcaac atcaatctcc gttttgaaaa aggacaagtt gttgtcctgc ttggaccttc
    21241 tggctctggg aagtccactc ttatccgtac gatcaatggt ttagaggctg ttgacaaagg
    21301 aagtctccta gtcaatgggc accaagttgc tggtgccagc cagaaagatt tggtacctct
    21361 tcgcaaggaa gtcggcatgg tttttcaaca ttttaacctt tatccacaca aaacagtgtt
    21421 agaaaacgtg acacttgcac ctattaaagt tctaggaatt gataaaaaag aagctgaaaa
    21481 aaccgccaaa aaatatctgg aatttgtaaa tatgtgggac aagaaagatt cctatcccgc
    21541 catgctatct ggtggacaaa aacagcggat cgccatcgct cgtggtcttg ctatgcatcc
    21601 ggaactcctc ctctttgatg aaccaacatc tgctcttgat cctgagacta tcggagatgt
    21661 tctagcagtt atgcagaaac tggcgcgtga tgggatgaac atgatcatcg ttacccacga
    21721 aatgggcttt gctcgagagg ttgcggaccg cattatcttt atggccgacg gagaagtttt
    21781 agtagatacg acagatgtcg ataacttttt tgacaatcca agcgaacctc gtgcccaaca
    21841 attcctcagc aaaattatca accacgaaag tgacaaagtc aaataaggag gcgcctatga
    21901 aaaaaaattc tttttatcag cattattgat tagccttttc ggccttgctg ctgccaaacc
    21961 agtccaggct gatacaagta tcgcagacat tcaaaaaaga ggcgaactgg ttgtcggtgt
    22021 caaacaagac gttcccaatt ttggttacaa agatcccaag accggtactt attctggtat
    22081 cgaaaccgac ttggccaaga tggtagctga tgaactcaag gtcaagattc gctatgtgcc
    22141 ggttacagca caaacccgcg gcccccttct agacaatgaa caggtcgata tggatatcgc
    22201 gacctttacc atcacggacg aacgcaaaaa actctacaac tttaccagtc cctactacac
    22261 agacgcttct ggatttttgg tcaataaatc tgccaaaatc aaaaagattg aggacctaaa
    22321 cagcaaaacc atcggagtcg cccaaggctc catcacccaa tgcctgatta ctgaactggg
    22381 caaaaagaaa ggtctaacct ttaaatttgt cgaacttggt tcctacccag aattgattac
    22441 ttcccttcac gctcatcgta tcgatgcctt ttccgttgac cgctctattc tgtctggcta
    22501 cactagtaaa cgcacagaac tactagatga tagtttcaag ccatctgact acggtattgt
    22561 taccaagaaa tcaaatacag agctcaacga ctatcttgat aacttggtta ctaaatggag
    22621 caaggatggt agtttgcaga aactttatga ccgttacaag ctcaaaccat ctagccatac
    22681 tgcagattaa ggaggacacc ccatgacaga tttatcatct tggacagcct attttcagga
    22741 ttttggacaa tttttcaatg gtttcctctt tactcttgcc ctagcgattg gattctttat
    22801 cctcgccatg gtcttaggaa tcttctttgg tgccatgtca accagtaaac gtccaatttt
    22861 acgcatttta gctcacatct ttgtggaatt ttaccaaaac actcccctct tggtgcagtt
    22921 tgttattgtt ttttatggcc tacctcttat cagtgaccat actatcatga ttccaattta
    22981 ttggacagct gttctctgcg tgggactcta tcacggcgct tatatcgctg aggttattcg
    23041 ttcagggatt cagtctattc ctagtggtca gatggaggcc gccttgtcgc aaggttttac
    23101 ctatatcagt gccatgcgct tgattacctt gcctcaggcc ttccgcatca ttctccctcc
    23161 attgaccaac caaattgtta acctcatcaa gaacacatct actgtagcta tcatctctgg
    23221 agtagacttg atgtttgtga ctaagtcttg gtcggctctc aacggaaact atatcccagc
    23281 ctttttaggt gctgctcttc tctactttgc cctatgcttc cctgttgccc agtttggtcg
    23341 caagatggag caagccaata aaaaagccta ttcactttag gaggttacta tggaatctat
    23401 tttagaaatt ttaaccccag ataacctagt ctttatcttt aaaggatttg gcttgaccct
    23461 ctatatttct ctgattgcca tcatcctctc tactatcatc ggtaccgtgc ttgccgtcat
    23521 gcgaaatgga aaaaatccta tcttacgcat tatttccagt atttatatcg agtttgtgca
    23581 caacgttccc aaccttctct ggatttttac tatctttttg gtgttcaaaa tgaagtccac
    23641 accagcaggt attacagcct ttactctctt tacatcagca gccttggctg agattattcg
    23701 aggcggtctc aatgccgtag acaagggaca atacaaagca ggaatgtcac aaggcttcac
    23761 ctcagcccaa atcctctact acatcattct cccacaagcc agccgcaaaa tgctaccagc
    23821 catcatttct cagtttgtta ccgtgattaa ggataccagt ctcctctact ctgttatcgc
    23881 cctacaagaa ctctttggag ccagccaaat tctcatgggc cgttatttcg aaccagagca
    23941 ggtcttcagt ctttacatcc tgattgccct catctacttc agctttaacc tagcaatttc
    24001 tagcctgtct catatgctag ccaaacgttg gcaacaagct gcagaataat actcttcgaa
    24061 aatctcttca aaccacgtca gcttcacctt gccgtatata tgttactgac ttcgtcagtt
    24121 ctatccacaa cctcaaaacg gtgttttgag cagcctgcgg ctagcttcct agtttgctct
    24181 ttgattttca ttgagtataa acagccactc tccagttcaa ttggagagtt ttttgatgag
    24241 agtagatatt tatagacctc aatttgacac catacatttt ctatgataaa atgtaacaaa
    24301 ttcatttaca acaaatcgaa atctaaatga aatggaattt tctatgaaat cagtcaaagg
    24361 actactcttt atcatagcta gttttatctt gactcttttg acttggatga acacttctcc
    24421 ccaattcatg attccaggac tagctttaac aagcctatct ctgactttta tcctagccac
    24481 tcgtctccca ctactagaaa gctggtttca cggtttggag aaggtctaca ccgtccacaa
    24541 attcacagcc tttctctcca tcatcctact aatctttcat aactttagta tgggcggttt
    24601 gtggggctct cgcttagctg ctcagtttgg caatcttgcc atctatatct ttgccagcat
    24661 catccttgtc gcctatttag gcaaatacat ccaatacgaa gcttggcgat ggattcaccg
    24721 cttggtttac ctagcctata ttttaggact ctttcacatc tacatgataa tgggcaatcg
    24781 tctccttaca tttaatcttc taagttttct tgttggtagc tatgcccttt taggcttact
    24841 agctggtttt tatatcattt ttctatatca aaagatttcc ttcccctatc tagggaaaat
    24901 tacccatctc aaacgcttaa atcacgatac tagagaaatt caaatccatc tttgcagacc
    24961 tttcaactat caatcaggac aatttgcctt tctaaagatt ttccaagaag gctttgaaag
    25021 tgctccgcat cccttttcta tctcaggagg tcatggtcaa actctttact ttactgttaa
    25081 aaattcaggc gaccatacca ataatatcta tgataatctt caagccggca gcaaagtaac
    25141 cctagacaga gcttacggac acatgatcat agaagaagga cgagaaaatc aggtttggat
    25201 tgctggaggt attgggatca cccccttcat ctcttacatc cgtgaacatc ctattttaga
    25261 taaacaggtt cacttctact atagcttccg tggagatgaa aatgcagtct acctagattt
    25321 actccgtaac tatgctcaga aaaatcctaa ttttgaactc catctaatcg acagtacgaa
    25381 agacggctat cttaattttg aacaaaaaga agtgcccgaa catgcaaccg tctatatgtg
    25441 tggtcctatt tctatgatga aggcacttgc caaacagatt aagaaacaaa atccaaaaac
    25501 agagcttatt tacgaaggat tcaagttcaa ataagtaatc atactctcct gggatttccc
    25561 aggagagttt tttatagcca aatgaaataa gaccggaacg atggaatttt ggcattcaaa
    25621 tcaattgata agaatatttt atagtggagt gaaataggat acgaacaaat tgattaggaa
    25681 aatcaaatga atttatagaa atcttttagc agttatgtta tcctattcta gtttcaaaac
    25741 gctatagaag cagcattgtg ctagtctaga ttcagtttac tatactaaaa cgagtagctt
    25801 gaaatcaaaa aacccaccct cacaggcagg ttttatctgt attattcagc tagattatgc
    25861 tttaccttct gaaccgaata cgtcgatacg ttcttcaacc gatgcttgga tagcttttac
    25921 accgtcagcc aagaatttac gtgggtcgaa gagttttttc ttgtcgtatt ctgcttcgtt
    25981 tgcttcgtaa tcacgagcaa atttacgagt tgcgttagcg aatgcgattt ggcattctgt
    26041 gttaacgtta actttggcaa caccaagttt gatagctgct tggatttgct catcaggaat
    26101 acctgatcca ccgtgcaata cgattgggaa tcctggaaga gcttctgtca atttttgcaa
    26161 gtggtcaagg tcaagacctt cccagtttac tgggtaaggg ccgtggatgt taccgatacc
    26221 agctgccaag aagtcgatac cagtttcaac cattgcttta gcgtcttcga ttggagccaa
    26281 ttcaccttta ccgatgattc cgtcttcttc accaccgata gtaccaactt cagcttctac
    26341 tgagatacct ttagcgtgtg ctttttcaac aacttcttta gccaatttaa ggttttcttc
    26401 aactggaagg tgtgaaccgt caaacatgat tgaagtataa ccaacttcga tacactcaag
    26461 tgcatcttcg tagtgaccgt ggtcaaggtg gatagctact ggtacagtga tacccattga
    26521 ttcaacaagg ttagcgatca agttgcgagc aactttgtaa ccacccatgt atttagcagc
    26581 acccattgaa gtttggatca aaactggagc ttttttagct tctgctgcgc gcaagatagc
    26641 ttgagtccac tcaaggttgt ttgtgttaaa tccaccaact gcataaccgt tgtcacgggc
    26701 tgcttggaca aatttttctg ctgaaacgat tgccatttta tcaggcctcc tgtatatttt
    26761 tatgggtcat cccatttaca ttgttcattt tatcactttt tgccaaaaaa atctagtttt
    26821 tcccgcagtt tcgattgatt ttcttctaac tccatctatg taaacccttt ctctccctag
    26881 tcttggacga cttttggaaa agctataaag aaggttaaac gattctcctc catctcgaaa
    26941 cgataagcta atttttcatg ttctaataga ctcttaacca caaaaagccc cataccagac
    27001 cccttgacct tgcgactggc attgtcagaa aaagactggg ctagtttttc ttgttcctct
    27061 gagctacagc tattttcgat aaaaagttct ccttctcttt ctccaattcg aactaagcca
    27121 cctggaacag agtgcttaat ggcattgctg atgagattag aaagaatcaa cttcataact
    27181 gatgggttta gataagcctg ctgatgggtc aaactattgt ctatctggag ctctctttcc
    27241 ttggctagca aggcataatc tttgaccaga tttttcgtca tctggaggag gtcaattgtt
    27301 tccctatcat ctcgcaattc ctgcacagaa gagagggaaa gtatctgcag aacatggtga
    27361 ttgagttcat ccacaatccc caaggcaact cccagatact ggtctctatc cttataacga
    27421 ccgatattct ctctcatatt ttcgattagg attttcaaac tagccagcgg tgttttcaat
    27481 tcatgagaag ctcctcgtag gaattcgacc ttcatcttct ccagctggag aatggcttca
    27541 ttcttttcat gcaagtccgc aataacagtc aagagatgct ggtagaggct attgatttgt
    27601 tccttgagat tacctatctc atccttagaa tccacgcgca atcgcacttg ggaatccagg
    27661 tccatcatcc gacgggtcac ccgcttgatt tccaaaatcg gtgcaacaat agtccgagcg
    27721 tagatgtagg ccaccaagag ggaaatcaga aaggaggcca gcaaggtata gggaagaaac
    27781 tggagactga tttgctccgc ttccttttgt aaatccatgg aagctagaaa ctggagaatc
    27841 atagtaccac cgtcttgcgt tttcacctcg cgctcctcaa taaagagaga ggttgtctgg
    27901 cggtctgtgt ccagaggaag actgtccttg acttctaact tgtcctcggt catctcacct
    27961 ttgacggtcc ccttgatatc actagtctgg gaatacaagt ctaacacttg ctcgatactc
    28021 tgcctatctt tcccttctag ggactgggca atggctgttg ccttttgacc aatggtttcc
    28081 tgacgatgac tcagataagt cgaaggaaaa agaaaataaa tagctaaatg aaggcagata
    28141 accagaacac taaatatcga gaaggtatag ataaatatct ttgtaaataa acctgttcgt
    28201 ttcattttcg ctccaattta taaccaacat tgcgcacagt gaagatacaa tccaagtcta
    28261 gctttttccg caattccttg atataaacat caataacacg gtcaaaggga acctcatctg
    28321 tcgctttcca gacggcatcg ataatctgag accgagtcaa ggcccggcct tcatttttca
    28381 ctagatagtc cagaatttcc aactctttgg cattgatagg cacttcttga cctgcgaggc
    28441 ttgcactgta gctttcaaag tccaccttgg tatccttgta agaaaagatt cgtcctgtat
    28501 cgtagtagcg cttgaaaatc gcgtccaccc tcacttttaa gagggagagg gagaaaggtt
    28561 tttccagata gccatctgcc aaagaggcaa aggcactcat cttgtattcc tcatcctgaa
    28621 aagctgtcaa catcaagaca ggaacctgac tggttttacg aatctcagct aggacttcta
    28681 agccgttaag cttgggcatc tggatatcca gtaaaaccag ggccacctca tagctagaaa
    28741 attgctccag agcttcctga ccgtccgctg cctcaatagt ttcatagcca caatccgtca
    28801 aataatcact gaccccctca cggatcatct cttcatcttc tacaattaaa attttcatac
    28861 tttaactgct ctctattttt tatttttctt agaataaata cctactctat tttctattat
    28921 agtctcttgc tggccttttg tctgtaagca actgaccact agataaaacg ttgtgaaatt
    28981 cctttctcat aaattccata actttagtat attatattta agcactaaag tacaaagaaa
    29041 gcaactgaaa gcaatgattt tcaccactgc tttcgattta ttttgaattg ttaaatagct
    29101 attcctatcc actattcttg aatagaaaca caagatgcaa tctttattcc agactcattt
    29161 tttcaaattt attcaccatc cagcaagagc tcttttggtt gttttctaag gagattgctt
    29221 gaagcaagcg ccataacgag aaccactaga accaaggcaa ggacaaaaat gatgataaag
    29281 tctgatgtct gaatggaaat gtctaggctc gacaaggtct tgctaaagcc atctacttct
    29341 gcaccgccac caaggttaga ggcttgagcc gccttactag cctgtttggc aacacctgaa
    29401 gtcacattgg caaggacagt gtttccaatt gcacgggcag tgtaattagc tagaaagtaa
    29461 gcagaaacta gagcagggat agcaatcaag atagattcgg ttatgaattg acccaagata
    29521 cttgcctgct tgaggccgat agagaggaga attcccactt ccttgcgacg ggcgttgatc
    29581 caaaggctga gcaagagggc aaggaggaga actgagaagc tcaagctacc ccagaagagg
    29641 aggttggcca tcttgtacat accagagata gattgctcaa gagctgggta gttagaggag
    29701 ctcttgacga gtgtgtagct cttccagttg ataccactga tgccattcaa ctctttcata
    29761 acatcatcca agttcttgtc tgctgttaca aagaaggttg cgtccccata aatggctgtg
    29821 tcttctgtgt atccataaag ttttgcagca gtgtgaatgt ctgtaatagc tgtgttttcg
    29881 taaagttctt gtgagtaggt tactgctgac ttattatgac catcaaagag tcccttgatt
    29941 gtcacttcaa ctgtttcctt ggctcctttt tcattatctg catcgtagat attagagtcc
    30001 agtttaacct tgtcccctac tttccagccg tgtttggctg ccaagtcctt gtgcaagagg
    30061 attttatcct tgtcgtcgtt ggttaagtgc tctccttcga ctagtttata agaaccagag
    30121 acaaacttgt cttctttaga ggagtcattg acacctgtaa tcatcaagct acttccaaaa
    30181 cgtttggcac gatcagcagt gagattcttc ttggtttctg gcgtttcaat caggtcatat
    30241 ccagtcaaat ctccgatagc gttgatacgt ttgacataag actcaatggc cttgttttcg
    30301 gtgatttttt tgatgtcttc acccttgata ttcccagcac cacgaggcgt tccttggttg
    30361 acgcgacgat tgatttgcat ggagaagcta ttggtgatat ttttaaaggt ctcctgagaa
    30421 gccttggcag tagctccctt gattgacaag ccgaccaaac tcaagctcgc cataaggaga
    30481 ataatcagga agatgacaat cgatttgaaa aacttccttg taacataggc aaatgcgttg
    30541 tgtaacatag attccctttc tagattttgt tttaatcatt ctattaaaat aagctcaaat
    30601 tatttactag tattgcgcgt ttcagtcagt ttcttatcct ttaattcaag tgtaatatct
    30661 gacgcttgtg ccacttcttt actgtgagtt acgacaatca cacatttacc tgttttctgg
    30721 gcaagtgatt tgagtagttc gacaatatct ccagcagttt taggatccag atttcctgtt
    30781 ggctcatcag ctagaataac tggagcttct gagaccaaac tgcgagcaat ggcaacacgt
    30841 tgctgttgac cacctgataa ctggagaaca ttccgcttga tctggctttc atccaaacca
    30901 agctcaagaa gtgtatcctt gcttgccttt ttgttgacca agcggatatt ttccagcgga
    30961 gaaagataat ctatcaagtt ataattttga aagaccaggg aaatatggtg catgcgatgg
    31021 taagaatagc ccttcttacg aatatcctct ccttgaaaaa ggatagaacc ttcaacagga
    31081 ctatctagac cagcaagtag ggacaagagt gtggattttc ctgctcctga ctccccaata
    31141 atactgtaaa attttccggg ttcaaaatta taatcgatct gatataggac tgcttcagca
    31201 gtattcttat aacggtaggt aacatcttgt aattgtaata aagtcatgat ttctccttct
    31261 taactaatag atgataaaat ttctttcggt gattttctaa ataagaatag gaaacaaagg
    31321 gctacagata agcaactaag cagaactaga aaaacatagg attctgcaaa agataagatg
    31381 ctagttgata aactgcttgc tttggctagt gtatcttgta agcttgcctg atctccactt
    31441 gctagtagag tttggagtag gtaagttgtg attccgtttc ctgcaacaaa tgctggaagc
    31501 aaagctccaa gagataccaa aactacctct aaacagaatt gtaggaagat cgagctcttg
    31561 ccttttccaa gtgcaagtaa aatccccact tcatagaccc gttctctcaa ccagagagac
    31621 aaaaccagaa ttaaggctcc agctcctgct atcaacatcc cataaaggaa gatggtcagg
    31681 aaggtttgga aagttgcaac tgagtctttg atttgttcaa aagccttgtt ttccttttcg
    31741 acttggtagc cttgattttc caaggccaag ttttctacct gcttcatgag tccgtccatt
    31801 tccttaggat tttctacata gaagcgtgct gcactgactt gagcttcact attgcccaaa
    31861 agggtttggc tactgtcata gtctgtaaag acttgatttt cactgaagtc agaagacaag
    31921 cctgtgaatt tctcttgttt tttaccagaa aagatgccga taatctcaaa ctctactgtt
    31981 tgtccttttc cagattcaga ctgaccagca tccaagccaa tcttgtcatg aagcgaaaga
    32041 ccgttcttct tagccaattc ttcgtggata aggattttct tggaatcccc tttttgaagg
    32101 tgtcgccctt cttttagatt gaaagccgaa ctggtaaagg ttacatcctt ggatgaatcc
    32161 tcaagagccg ttaagctaac caagttattg tctgcagctg ataaatcatc acgctccacg
    32221 ctctgctcgc cagtcactgc ttccttgtct tttagttttg cgaccgtctc aagttcagga
    32281 gagacatttt ccagcccctt aatcttgctt acagatgcta ggtctgacaa cttgaatgtc
    32341 tgaccattct ctatcttctt aatagaaaaa gatgtattga gtgatttata aagattgctt
    32401 tctactgttt tgttggactt catcagagtc aaacaggctg aaattccggc caataagacc
    32461 aataaaatca gaaataaaat aaaacttctc agtcgctttc tgctgacata agcccaagat
    32521 ctttggattg gattcatttg tcacctccat atttgtaaga ctattataaa acccaaatat
    32581 gaaatgttta tgaaatacga aaaaaaaata tcgagtaggg gataatctct agcccctctc
    32641 acaccacc
//
LOCUS       DAVHSY010000021        31855 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.021, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000021 DAVHSY010000000
VERSION     DAVHSY010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31855
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.021"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..159
                     /locus_tag="VVR43_001200"
     CDS             <1..159
                     /locus_tag="VVR43_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6149564.1"
                     /translation="HYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKER
                     TKFVLSRA"
     gene            complement(330..1892)
                     /gene="guaA"
                     /locus_tag="VVR43_001201"
     CDS             complement(330..1892)
                     /gene="guaA"
                     /locus_tag="VVR43_001201"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU6149565.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2034..2732
                     /locus_tag="VVR43_001202"
     CDS             2034..2732
                     /locus_tag="VVR43_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6149566.1"
                     /translation="MLPAYMKIHDQIKKDIDEYRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPERFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(2775..3671)
                     /locus_tag="VVR43_001203"
     CDS             complement(2775..3671)
                     /locus_tag="VVR43_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU6149567.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFTIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(3680..4615)
                     /locus_tag="VVR43_001204"
     CDS             complement(3680..4615)
                     /locus_tag="VVR43_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU6149568.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(4612..5337)
                     /locus_tag="VVR43_001205"
     CDS             complement(4612..5337)
                     /locus_tag="VVR43_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU6149569.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(5421..6056)
                     /locus_tag="VVR43_001206"
     CDS             complement(5421..6056)
                     /locus_tag="VVR43_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU6149570.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKMIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     ETLNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(6058..6885)
                     /locus_tag="VVR43_001207"
     CDS             complement(6058..6885)
                     /locus_tag="VVR43_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6149571.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(6907..7242)
                     /locus_tag="VVR43_001208"
     CDS             complement(6907..7242)
                     /locus_tag="VVR43_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEU6149572.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEGGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(7243..7959)
                     /locus_tag="VVR43_001209"
     CDS             complement(7243..7959)
                     /locus_tag="VVR43_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEU6149573.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNGIKAALLAYSYGFNGIEQYISKEDYNRYLSD
                     LNEDKMKAEIERAEKEADITIIMLQMGVEYQLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIIY"
     gene            8472..9083
                     /locus_tag="VVR43_001210"
     CDS             8472..9083
                     /locus_tag="VVR43_001210"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU6149574.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9128..9856
                     /gene="rlmB"
                     /locus_tag="VVR43_001211"
     CDS             9128..9856
                     /gene="rlmB"
                     /locus_tag="VVR43_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU6149575.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(9894..10805)
                     /gene="trxB"
                     /locus_tag="VVR43_001212"
     CDS             complement(9894..10805)
                     /gene="trxB"
                     /locus_tag="VVR43_001212"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU6149576.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQVFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(10871..11095)
                     /locus_tag="VVR43_001213"
     CDS             complement(10871..11095)
                     /locus_tag="VVR43_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU6149577.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11173..11916)
                     /locus_tag="VVR43_001214"
     CDS             complement(11173..11916)
                     /locus_tag="VVR43_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6149578.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRRLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(11916..12716)
                     /locus_tag="VVR43_001215"
     CDS             complement(11916..12716)
                     /locus_tag="VVR43_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6149579.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(12874..13230)
                     /locus_tag="VVR43_001216"
     CDS             complement(12874..13230)
                     /locus_tag="VVR43_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU6149580.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13224..13754)
                     /locus_tag="VVR43_001217"
     CDS             complement(13224..13754)
                     /locus_tag="VVR43_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU6149581.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(13754..14248)
                     /locus_tag="VVR43_001218"
     CDS             complement(13754..14248)
                     /locus_tag="VVR43_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6149582.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14383..14829
                     /locus_tag="VVR43_001219"
     CDS             14383..14829
                     /locus_tag="VVR43_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU6149583.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            14826..15473
                     /locus_tag="VVR43_001220"
     CDS             14826..15473
                     /locus_tag="VVR43_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU6149584.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     NQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(15494..16075)
                     /gene="pdxT"
                     /locus_tag="VVR43_001221"
     CDS             complement(15494..16075)
                     /gene="pdxT"
                     /locus_tag="VVR43_001221"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU6149585.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(16076..16951)
                     /gene="pdxS"
                     /locus_tag="VVR43_001222"
     CDS             complement(16076..16951)
                     /gene="pdxS"
                     /locus_tag="VVR43_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU6149586.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17103..18482)
                     /locus_tag="VVR43_001223"
     CDS             complement(17103..18482)
                     /locus_tag="VVR43_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU6149587.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            18776..19699
                     /locus_tag="VVR43_001224"
     CDS             18776..19699
                     /locus_tag="VVR43_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU6149588.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            19759..20364
                     /locus_tag="VVR43_001225"
     CDS             19759..20364
                     /locus_tag="VVR43_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU6149589.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEEFDWENL"
     gene            20382..21626
                     /locus_tag="VVR43_001226"
     CDS             20382..21626
                     /locus_tag="VVR43_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU6149590.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGSHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(21743..22000)
                     /locus_tag="VVR43_001227"
     CDS             complement(21743..22000)
                     /locus_tag="VVR43_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU6149591.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(22042..24078)
                     /locus_tag="VVR43_001228"
     CDS             complement(22042..24078)
                     /locus_tag="VVR43_001228"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU6149592.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVHIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24338..25255)
                     /gene="glyQ"
                     /locus_tag="VVR43_001229"
     CDS             complement(24338..25255)
                     /gene="glyQ"
                     /locus_tag="VVR43_001229"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU6149593.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(25448..26209)
                     /locus_tag="VVR43_001230"
     CDS             complement(25448..26209)
                     /locus_tag="VVR43_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU6149594.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(26482..27324)
                     /locus_tag="VVR43_001231"
     CDS             complement(26482..27324)
                     /locus_tag="VVR43_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU6149595.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEKSVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERENLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(27438..28829)
                     /locus_tag="VVR43_001232"
     CDS             complement(27438..28829)
                     /locus_tag="VVR43_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU6149596.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(29064..29441)
                     /locus_tag="VVR43_001233"
     CDS             complement(29064..29441)
                     /locus_tag="VVR43_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU6149597.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            29656..30633
                     /locus_tag="VVR43_001234"
     CDS             29656..30633
                     /locus_tag="VVR43_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU6149598.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            30630..31712
                     /locus_tag="VVR43_001235"
     CDS             30630..31712
                     /locus_tag="VVR43_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6149599.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     ILRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     TEEIKKLKKFASIREIVLKNQELYIK"
BASE COUNT         9432 a         7168 c         5720 g         9535 t
ORIGIN      
        1 cactattcta atgccaaact ggaagcgacc aataatctca tcaaacttat caagcgcaat
       61 gcctttggtt ttcgaaactt tgaaaacttc aaaaaacgga tttttatcgc tttgaacatc
      121 aaaaaagaaa ggacgaaatt tgtcctttct cgagcttagc tgacttcaac ccactacagt
      181 tgacaaagag ccattttttg tccaaatgta aaccacttgg aactattatt caatttattc
      241 tttttagtaa atgttcccgt tttaatccca gttacagttt ttaatcctct gtaaccgttg
      301 attttacaaa gcttttaatt tttttgcgat tactcccact caactgttgc aggtggttta
      361 cttgtaatat cgtagacgat acggttaaca tgatccactt catttacgat acgtactgag
      421 attttttgaa gtacttccca tggaattttg gcaaaatcag cagtcatacc atcgatagaa
      481 gtgatagcac ggattgcaat cgtgtagtca tacgtacgac cgtcacccat aacaccgact
      541 gaacgaacgc ctgtgttaac agtgaagtat tgccaaatat cgcggtcaag tccagcttta
      601 gcgatttctt cacgaagaat agcgtctgat tcacgaacgg tttcaagttt ctcttcagtg
      661 atttcaccca tgacacggat agcaagtcct ggtcctggga atggttggcg ccatacgata
      721 tggtctggca taccaagctc tgtaccaaga gcacgaactt catccttgta aagagtattg
      781 agtggttcaa tcaattcaaa ctgcatatct tctggaagac cacccacgtt gtggtgtgac
      841 ttgatagttt gagctgtatc cgtaccagac tcgataacat ctgtatataa agtaccttga
      901 gcaaggaatt tcacatcttt gagcttgctt gcttcgtcat cgaatacata gacaaactcg
      961 ttaccgatga ttttacgttt ttgttcaggg tcagaaacgc cagcaagttt gtcaaggaaa
     1021 cgtttagcag cgtctgcttt gacgatattc aaaccaaact taccaccgag catgtccata
     1081 acttgatcag cttcgccttt acgaagaaga ccgtggtcta cgaagataca gatcaattga
     1141 tcgccaatcg ctttttggag aagaacccca acgacagatg agtcaacacc acctgataga
     1201 ccaagaagga cacgtttatc accgacggtt tcacgaattt ttttgatctg catgtcaatg
     1261 aaattatcca ttgaccagtc acctttagcc ttacaaatgt taagggcaaa gttacgaagg
     1321 atatcatttc cgtatacaga atgacgaact tctgggtgga attggatacc gtaaatgtgt
     1381 ttatctgggt tttcgatggc tgcgtatggg cagtcagctg atgtacctgt acgaacaaag
     1441 tcagcaggaa tctcagtaac cgcatcacca tggctcatca aaacagtctg ttcatcaggt
     1501 gttgattcaa aaagcgctga tggtgtgtga gttagggttg attgaccgta ttcacgattt
     1561 ccagcatcac ctgcaggaac aacttttcct ccaagtttat gggtcaataa ctgcatacca
     1621 taacagattc ccaaaattgg aattccgagt tcgaagattt ctgggtcaat atcaaatgaa
     1681 ccatcttcat atacagaatt tggaccacct gatagaataa ttcctacagg attgacttca
     1741 cgaacttcag cagctgaaat tttatggctt tttagttctg aaaaaacacc aatctcacgg
     1801 atacggcgtg aaatcagctg gttgtactgg ctaccatagt ccaatacgat gattttttct
     1861 acatcttgca aatcagttga aatgttgctc atctttttcc tttctcaaaa gaaatatctt
     1921 ttcccaatat tctatcacaa ataagggcga attaccaact aaacaaggca aagtttgact
     1981 ttttctagtt tattggggta caatagagaa aagatagaaa tgaagtgaaa aatatgctac
     2041 ctgcttatat gaaaatccat gatcagataa aaaaggatat tgacgagtac cgttgggcta
     2101 ttggtgagag gcttccaagt gaaagagatt tagctgagca gtttgcggtc agtcgtatga
     2161 ccctccgcca agccgtatct ctattagtcg aagaaggcgt cttagagcgc cgtgtaggaa
     2221 gcggcacctt tgtttccagt actcgagtac aagaaaagat gcgagggaca accagtttta
     2281 ctgaaattgt caaatcccaa ggtaaagttc cctctagcca gctcatttcc tacaaaaaaa
     2341 ccattcccaa tgagcaagaa gttgccaagc taggaatttt tccaacggac aatattatcc
     2401 gaatggagcg ggtccgctat gccgaccaag ttcccctagt ttatgaagtt gcttctattc
     2461 ctgaaagatt cattaaggac tttaaaaaag aagaaatcac cagtcatttc ttccaaacct
     2521 tgcaaaaaca tggttatcgt atcggcaaat ctcaacagac catctatgct cgccttgcta
     2581 aagaaaagat tgcccactat ttggaagttg aaaaaggaca tgctattctt ggattgaccc
     2641 aggtttccta cctagaagat ggtactgctt ttgaatacgt aaaaagtcaa tatgtaggcg
     2701 aacgttttga attttatctt gaaaataatt agattaccac gcaaaaactc tctgtcacgg
     2761 acaaagagtc ttttttattt ttctaagaat aaatctttca aagaaatcaa agttacagca
     2821 aacaatatca ttgccatacc aagaaaatca atgggataaa attgttcatt cattattaag
     2881 aaggcaaaga aaaccgccga tattggctca attgaagcca acaagcttga cttgaccggt
     2941 cctatcagac tggctccttt aaggaaagct gtataggcaa agacagtccc gataaggata
     3001 atgcctgcaa acgcaaggag aaaatcaaga ctagtcggga tatcggcctg tagaacccct
     3061 gtaaaaggaa gggcgaccaa acctgctatg accattccca caccaatgac caagctgctc
     3121 ccccactttt taatcaaggc tatgggtaaa atgatataca gagcataagt caaggcagaa
     3181 aagagacccc agaacagacc agcaggtgtc atggataact ggtccaactg cccatgtgtt
     3241 gcgatcagga aggttcctcc gatggtgaat atgatggaaa ctatctctcc cagtgtcggt
     3301 gccaccctat ccttgataca gctataaatt aaaattccga caggacaaac atactgaagc
     3361 accgtcgctg ttcccgcatt ggtctcctga atagcagaca gataggcgaa ttggttgaga
     3421 aaaagaccaa tcagagcaaa aataagaaga gacagcaaac tctttctatc ctttaaaaag
     3481 accagtattt tatcctttgc agtagcataa gccaagagca tgagaattcc accagcgatt
     3541 aaaagacgca agttggttaa gaccagagcc gaaattccgt gtgccatcag gtattggcca
     3601 ctcgttcctg acaaccccca agcaatacca gccacaactg ttagtaaagt cccttttaaa
     3661 ctatttgaca tgtctctcct tactcttctt tgcgaatcaa gttcatcact tgattgcggt
     3721 ctaatatcca ttgagctctc tcgtcctttt cataggtacg attcgatagg aaaatagtgg
     3781 cttcttgctt ctgacgattc cacatgataa aggtacctgt atagcccgta tggtctagcc
     3841 aatctccttc caaattccat gctaaagaac gttccttgtc atccaaagga gaaaaatttt
     3901 gacttaagtc tcttgcaaaa tcatctgcta aatagtgttc taaaaagatt tgtaaatcct
     3961 ttatagtcga aaataaacca gcgctcccag catgtctacc caggagacga gccttgggat
     4021 catgcactat gcctgcctct acacctctaa ctgttggaac agcaagctca actggcccaa
     4081 acttggtttc cgtcattccc caaggtttcc agacttgatc ctttaaaatc acatccaaat
     4141 cttgattaaa aattctttcc aaaataaagc ccaacagcaa aaaatggaca tccgaataaa
     4201 gaaaggctgg ctgacttcgt ctgttgagat gaaacatcgc ttcctttaat tcaggggctg
     4261 ttaaaagatc acgattagga ataaaaggat caaggtctgt tgcatgagtc aagagctggc
     4321 gaatagtaat gtctggataa tcactctcag gtaaaaaatc tattaccagt ctatcaatat
     4381 ctaattgacc tatttcccac aagaaggtac aaactgtgcc aaccccaaca accttgctga
     4441 cactagctag gtcataaact agtcctgcct cagtctgcaa gccatgctct gggtcactct
     4501 ggcctaaata gaactctgtc cattgattgt ccttaaaata cgcaaaagag gctccgggat
     4561 aaattcctgc ctcgatttgt tcttctattt ttttaataat cttggtccac ttcatacttc
     4621 ttcaaaccac aattcaacat tatttctatc tttaccaagg aagaattttt cagacttagg
     4681 aataaaatat tcagtagact caaacttctg gcgaagactt gctatgtcta attcattgac
     4741 caagaacttg agcatagata agtcccaggt aaccgtattg tccacagtca aatcctgccc
     4801 ctgagctgga ataaaatcaa gggatgcccc aatttcagat gattccaaga aactttcgat
     4861 atcagttggg agatgtaatt ccatagaaat ctcaaattta cttaaagaaa ttgatgccaa
     4921 atctgtttga aattcaggct tttctcctac ttctactaga cttgctctgt catcttccgc
     4981 atgaatcaaa atcaaatcat cttctggtga gaaaatttca aaagcgtagc cattttgacc
     5041 tttatataat cgatgaatcg aatctgtttt agataagatt ccttcaattt ctaagggatt
     5101 ttccaccttg acaatcaatc tagctagttt ttttcttccc tctaccttac gagtacgcat
     5161 actgggagct tcttctaaaa ccagcttttc aagacccgtt tggtcaccta gtgacagaaa
     5221 ggccgattct tctaacaagg ccttcattcc aagggtttca atataaaatg tttcatttaa
     5281 ttttctatta ttagctttta aagtaggaat aatccgtaca atctgattta cattcataaa
     5341 ttcctccgtc actttttatt ttaaaggatt ttagaatttt ttacaagata ttatgctcaa
     5401 atttaacatt atttagctat ttagtaaaga tagtctttca aggcttttga caaagcctga
     5461 taaccagcaa tactgaggtg cagtccatca gttgtatatt cttttttgag ttggcctgct
     5521 tggtctgtca aacaatcaaa tactggcaca aattccacct gcatataggc agatgcaagc
     5581 tcttgatagg cttgattcca attctgaatt ttttcattcg agcggatata gactgcctgc
     5641 tggtactcct ctccctcatt gacaggcaaa atggaaagca atttaatctc tgtcaatgga
     5701 taatcgcgag caacggattg aatgatagct tcgagattat tgagagtctc attcacagga
     5761 acatcctttc cgatatcatt tgtcccaatc agaagaaaaa ttttatctac tgctccacca
     5821 tatagatgag catcaaggtt ctctagtaac agtcctgtct gatagccacg aattcctcga
     5881 ttgacaatca tctttgaagt tccaaatagc tcctgtagag gataatactc gacaatggaa
     5941 tccccaataa aaagaatgtt tggttctaca acagaaatgt gatttaggtg acgatatttg
     6001 gtttgaattt tttcttgttc ctttagaagc caattttcta ataactgtac tgccacttca
     6061 ttctcctttt tctaaccagt tttccaagac ttgataaact cctccttggc tgttggctgg
     6121 tgctagagca gtcgccacag ctttggcttt ctcatcagca ttttccatcg cataggcaat
     6181 tccagccatt tcaagcattt caacatcatt ttcactatca ccaaaagcca tgatttcttg
     6241 ggatttcaag tcccagcgct tgagtaattc ctccaagccc catgctttat gaatcccagc
     6301 ttggaggata tcaatgcaac catagccact ggatacagct cggacacggc catcaaagag
     6361 agcattgatt tcttccaaaa ccgaactcaa acgttcctca ccaacaacca tgctcatctt
     6421 gagcacacca ccaaagaggt cagatgttaa ttcatccaca aattgcatcc gttggtagaa
     6481 tttttcaatc atttctggag tcataaaact ttcaagatct gtaaaaatcg taccttcctt
     6541 gacaaaatca cccttcatcc ccgttacaac aaactggtcc tgacacgctc gacccttgaa
     6601 atgagccaaa gccttgttga caatggcgtc atcccatgtc tgagcctgaa tcaattcatt
     6661 gttttcaaaa atacgagcgc cattagcaac aaccagaacc actcgatcca ccaagggact
     6721 cagtagttgt ctcatgcggt gaatttcatt gcccgtcgca atgacaaaac gaatgcccct
     6781 ttgatccaac tgatctaaaa tcttttccaa tcgtgggaga tcaagctgac ctctagcatc
     6841 cagcaaggtc ccatccatat ctgtcgcaat taccttaatc atcatttact ttcctctgga
     6901 ttcaagctaa taccacttca atcccacatg ttcattcatt tctttatagg ctgtatcaat
     6961 tcgttcctta gtcgcttcat ctaactggtc acgatgactg ccaccctcta taaaatcttc
     7021 caaaatataa gtttggtaat gatacaaggg atatccttct ggtgaaaagg ttccctttgg
     7081 tgttcgattg acccaagtag gatgagcttt agctgttccg atagttgttt ttccatcctt
     7141 cttcttgatg gtgacatcca tgagaacacc acgttcagtc cacttagcat tctcttcatc
     7201 tcccatagat tcaatccgtt gattggaaat gaagttcccc atttaataga taatgagctt
     7261 cttatctcca tctttttcaa ccgtttcaga tggttcaaca acgtgaggat gccctccaaa
     7321 gataatatcc gctccccaat cgatcatctt gtgataaaga gctttttgtt cttcagttgg
     7381 ttccaattga tactcaacac ccatctgaag catgataatg gtgatatctg cttccttctc
     7441 tgcccgttca atttcagcct tcatcttatc ttcgtttaaa tctgaaagat aacgattata
     7501 gtcttcctta gaaatatact gctcaattcc attgaaacca taggaatagg ctaacaatgc
     7561 agccttgata ccattcactt ccttaatgac cagcggagcc tgatcacgtg gttcgtgcgt
     7621 ataaactccg attggagtga ttccagcttt ctcaataata tcggccgttg aaataactcc
     7681 ctcaatttgc gaatccaaaa tatgattatg agctaaatcc agcacatgat aacctgcctc
     7741 cttaatagca tccataactt caacaggagc attaaagaga agataacccg ctaaataatg
     7801 atccttatta atggttcctt caaaatcacc aatagctaaa tctgcttgct tgagccaagg
     7861 agtcacatac tcaaaatttt catgaaagtc ataggtaccg tcttcttttt tagctgaaaa
     7921 gaaaagtcca tcgtggtaga gcaaatcccc atgggccata attctggcag ttttttcctc
     7981 ttcctactcc tgagactttt gcttagtccc ctcttgagaa atagtatctc gtttttgact
     8041 agtcaaggga ttccttggaa gctttcaaac aacaagatca agcccattga taaaccaact
     8101 gctagcaaga gtatcgccac aaatccctta ttgctccact tgcgataact cctaaaaagt
     8161 ttaccaagcc cttcataaaa cgaaaagcta aaccaccctg atttcgattt tgtcttcttt
     8221 gtatcttcgt tctccctact ttcttatgca agccttttct ttttattata tcacagataa
     8281 gtatttcttt cacaattgaa ttgaacttcc catctatttt ctataaatcc taaatgccat
     8341 aatgctttca attcttgtca ttttgtgata tcatgtagag gaaatgaact aatccacagt
     8401 ggcttattcc aagtatacca cttgggcttt ggcagtaact aactgcacta aacataatat
     8461 aaggagagaa aatgtctgca atagaacgta ttacaaaagc tgctcactta attgatatga
     8521 acgatattat ccgtgaaggg aatcctactc tacgcgcgat tgctgaggaa gtcactttcc
     8581 ccctatctga ccaggaaatc atcctaggcg aaaagatgat gcaattcctt aaacattccc
     8641 aagatcctgt catggctgaa aaaatgggac tccgcggtgg tgttggactg gctgctcccc
     8701 agttagatat ctcaaaacgc attatcgctg ttttggtacc taatattgtt gaagaaggcg
     8761 aaactccaca ggaagcctac gatttggaag ccattatgta caatccaaaa atcgtctctc
     8821 actctgttca agatgctgct cttggcgaag gagaaggttg cctgtctgtt gaccgtaacg
     8881 tgcctggcta tgttgttcgc catgcccgcg ttactgttga ctactttgac aaagatggag
     8941 aaaaacaccg tatcaaactc aaaggctaca actccattgt tgttcagcat gaaattgacc
     9001 acattaacgg tatcatgttt tacgatcgca tcaatgaaaa agacccattt gcagttaaag
     9061 atggtttact gattcttgaa taaagaaaat cccgttgcaa gacggggttt tgtgttataa
     9121 tagaggcatg aaaacaaatg atattgtcta tggcgtccac gccgttaccg aagccctcct
     9181 tgcaaataca ggaaacaaac tctacctcca agaagatctc cgaggtaaga atgttgagaa
     9241 agtcaaggaa ctagctacag aaaagaaggt gtccatttct tggacatcaa aaaaatctct
     9301 ctctgagatt actgaaggtg ctgttcatca aggttttgtt ctacgagtgt ctgaatttgc
     9361 ctatagcgag ctagattaca tccttgcaaa aacacgccaa gaagaaaatc cacttctatt
     9421 gattctagat ggtctaaccg atccccataa tctaggttct atcttgcgaa cagccgatgc
     9481 gaccaatgtt tcaggtgtca tcattcccaa gcaccgtgct gtcggagtaa ctcctgtcgt
     9541 tgccaaaaca gccacaggtg ctattgaaca cgttccaatt gcccgagtga ccaacctcag
     9601 tcaaacctta gataaactta aggatgaagg tttctggacc tttggaacgg atatgaacgg
     9661 tactccttgc cacaagtgga atacaaaagg gaaaatcgcc ctcatcattg gaaatgaagg
     9721 aaaaggtatc tctagcaaca tcaaaaaaca agtcgatgag atgattacca ttccgatgaa
     9781 tggacatgtt caaagcctta atgccagtgt tgctgcggcc attctcatgt acgaagtttt
     9841 ccgaaataga ctataaaaag tttccagtca tctgattgga aactttttta taattaacta
     9901 tgttctgtaa tgaatttata ggcttcttga ccagcgatag ctccatctcc aaccgctgtt
     9961 gttacttggc gaaggtcttt caagcgaaca tctccaactg caaagatacc gtcgactgca
    10021 gttttcatgt ggttatctgt cacaatccat cctgcctgat cttggatatt caattcttta
    10081 acaaaatcgc taagagggtc caaaccaaca tagataaaga caccaccgaa gacttgttct
    10141 gtcacttgac ctgttttcac attttcaaat acgactgatt ctactcggtt ttcacccttg
    10201 atttccctta ctacagaatc ccagataaag ctgatttttt cattcgcaaa ggcgcgatct
    10261 tgtaaaacct tttgggcacg aagttggtca cgacggtgaa caatggtaac agtcttagca
    10321 aaacgagtca agaagagggc ttcttcaaca gctgaatctc caccaccaac taccaataaa
    10381 tcttggtcac ggaagaaagc accatcacac acagcacagt aagaaacacc acgactgttc
    10441 agttcttctt ctccaggtac tcccaaagga cggtgtttag aaccagttgc tacgataact
    10501 gtacgtgttt catatgtttg gtcatcagtc atcactttct taaaatcacc atggtcttcg
    10561 acattttcaa cataaccata aatgtgctcc acaccaagat tttcaagtgg ttcaaacatc
    10621 ttttcagcca attcaggtcc actaatatta gcgtatcctg ggtaattttc gatatcagat
    10681 gtattattca tctgaccacc tggcagacca ccttcaatca aagctacttt tagattgctt
    10741 cgagcagcat acaaggccgc agtcatccct gcaggtccag caccgataat aatagtatcg
    10801 tacatataga ttccttcttt cttgttgtaa ctatctttat tctaactctt tcttgtcaat
    10861 cacgcaagga ttatgccttg aaaacaagaa ttaaactcat aaccgcaaag gataatactg
    10921 ggacaaccaa gactccaatc ataatcatat catagagatg ggcttgacga gccctggctg
    10981 tcttatcaac tcccgacatg gctctcagac caatccaaat ccctaaaaaa atcagaacaa
    11041 ggatggtggt caagatcaaa ctctcgaaat ataaagaaaa tagttgcagt agcatgattt
    11101 ctctcatttc tatctttttt aaagagtaaa ctcagctagt ccaactaact gagttttcct
    11161 ttatctatta tatcaaatat aagtccgttt gtaactagcg aagaattctt ttgtccgctc
    11221 ttctttaggg gtgtggataa tctcatccgg agttccagac tcgatgattt tccccttatc
    11281 taagaagaga attttatccg caacttgggc tacaaaggac atgtcatgac tgaccaaaat
    11341 catggtctga cctgacttag cagcatctgc aatagacttt tctacttcac cgaccaattc
    11401 tgggtcaagg gctgaagttg gttcgtctaa gagcaaaaca tctggtttca tagcaagcgc
    11461 acgcgctagg gcaacccgtt gcttctgtcc acctgataaa cggcgaggat aatggttttc
    11521 acggtccgaa agcccaacct tagccaactc ttccttggca atcttagtcg cttcttggtc
    11581 agataatttc ttgacaacaa ccaagccttc tttcacatta tcaagtgctg ttcggcgttc
    11641 aaacaaatta aactgttgga aaaccataga caacttacgg cgtagggcaa ggatttcttc
    11701 ttgagtgatt ttagaaaaat caactgaaaa accatcaatc tgaatagagc cactgtcagg
    11761 tgtttcaaga taattgagac tgcgaagaaa ggttgatttt ccagctcctg aagaaccaat
    11821 caaggctacg acttctcctt tttgaatatc caagttcaga tgatccaaga cagtctgtcc
    11881 tgaaaaggat ttgcttaaat tcgaaatctt aatcattaac gaaggtctcc tttcacatct
    11941 gtttgcactg tatcaggtgc agaaatagcc atttttctct cgatgaaacg accgaggctt
    12001 tcaattccga tattgactac ccaataaaca agggcaacgg agatgaagcg ttcaaaatag
    12061 cgataatcag ctccacctag aatctgagct tgggcaaaga cttccacaac acccgcacta
    12121 aaagctagag atgttccctt ggtcaaaccg atgagggaat taatcaaggt tggagtagct
    12181 accaccgctg cattaggaat aatcactcgt cgataaactt gcgctcgggt catacccaga
    12241 ctgcgtgccg cctcaatctc accaggatta actgagagaa tggctgcacg aatggtttca
    12301 ctagcataag ctgcctcatt aaaggcaaag gcgacaatcg caaaagctgc agctggaatc
    12361 gcattgatat tgagaccagt tccccattgc tgattgaggg ctttcaaagc caaaggaatt
    12421 ccgtagtagg tcaacatgag ttgcaccaaa atcggtgtcc cttttaagaa actaacaaag
    12481 aaggcctgca agggatataa aatcttgaca cgattgatct tcacaatggc aaaaagaagc
    12541 gccaaaacca agccaaaaag ggcaccgcca attgtcaaca taattgttgt tggaagttgt
    12601 tggacaattc tagggattcc atcaaagacc gaacgtaggc taaacagctt gccatccgga
    12661 atcaattgca tcaagttttg gtaccaatct gatgctaaaa tcgttgtaac attcataaaa
    12721 acatcctctt ctgataatga ttcattctac catgcttctg ccgtcaatga aattatttgc
    12781 tacggtcaga tacagacttt gtctacctac tagtttatca tactttgaaa cagggaagtt
    12841 atatatttta tctatcaaag agatagataa aaactatttc agtcccagtt cttcataaga
    12901 ttttcgataa ccgatttgct taacagttcc attttctact aaaatgggcc gttttaacaa
    12961 cataccgtca cttgctagca actcagccgc ttcttggttt gacaaacttc ctaccttatc
    13021 ttttagccct aattcacggt atttgatacc actggtgttg aaaaattgct tcaattcaaa
    13081 tcctgaggtt tctagccaat tcaaaatgac ttcttggcta ggtgtttctt ccacgatatg
    13141 gacggcttta tagtccacac ctaattgatt taattcttgt tttgcttttt tacaagttga
    13201 acatttgggg tattcgataa attctaacat gtgcttctcc ttctattgtt tctatcttta
    13261 aaatctactc cttcatgctc caagagccaa gctttctttt ccactcctgc agcataacct
    13321 gtcagacgct tgcctgctcc caacacacga tgacaaggta ctaggataga ccaaggattg
    13381 cgtcccactg ctccaccaat tgcttgagca gaagccactt gcaggtcttg agcaatttgt
    13441 ccataggtca ctgtctgacc ataaggaatg ccctgtaaat agtcccaaac tctcttttca
    13501 aaattcgttc cgattggcgc caagagcaag ttggataaat cctgaggctt gcctttaaag
    13561 taatcatcta agcaagcaat aactgggtct aaaataggat gactaacaac ttcttctatc
    13621 gtttcatctc ctagtcccct ctcaaaatgc ttctgctcct gaacccaaat tccatacaaa
    13681 taatggtcat cagctacaag tgatagaata ccaattggtg aggagtagag gatttttaca
    13741 tacttctttt gcattatttc tttaattttt gataggccaa gcgttcgcca tctactggca
    13801 ccttaccaac ttgtttaaaa ccaagttttt caaaaatatg ttgcataacc ttgttttcag
    13861 catgcgtatc tgagcgaaaa tcaagataat caaaaccttc aatcaagccc tctaagaagg
    13921 tttgagcaac tccttttccc tgcacatctg ctgccacagc aatacggtga aagactagat
    13981 actctgactc tcccgcttgc cagtttccct cataaatagc ttcataggcc tcctctggac
    14041 tcttggtcac agcagcatag gctagcagtt ctccctcttc caaggctacg taggcttgcc
    14101 ctgagatgat atcatcgata ataacatctg catttggata gccattttgc cactggtcac
    14161 taccagcatc tgctaaacat tttttggcat cctccatcac ctgcatgatg gcatctactt
    14221 catttggaaa agctaaacga atttccatct tttttcctca tttctgacta gtttctccca
    14281 tcatagcata atttaagtat ttctacaagc agttaaaact tgactttgtg tttttgttat
    14341 tttataatct agttatcaaa actatataaa aaggagttga aaatgaaaac taccttttcc
    14401 tacccaaaat gggcagaaat tccaaacatt gacctctatc tggaccaggt tttgctctat
    14461 gtcaatcagg tctgcgcccc tatctctcct aataaagaca agggcctaac agcatctatg
    14521 gtcaacaatt atgtgaaaaa tggttacctg acaaagcctg acaaaaaaaa ataccaacgc
    14581 caacagattg cccgtttgat tgctatcaca accctcaagt ctgtattttc tattcaagaa
    14641 atagcccaga cacttaatac tctacaaact caagcaagtt cagaccaact ctacgatgct
    14701 tttgtggact acatgaacca aggaattgac ccagctaacc ctattatcca aaccagctgc
    14761 caaaccgtta aactctatca tcaaactcta gacttaatcg atcatactca agaggaggta
    14821 atccaatgaa cactagtctt aaactcagca aacaactcag ttttggagag gagattgcta
    14881 atagcgtgac ccatgctgtg ggtgcagtca tcatgcttat cttgctgcct atttcatcca
    14941 tctatagtta tgaagcacac ggatttttat cctctatcgg cgtttccatt ttcgtcatca
    15001 gtctctttct catgttccta tcatccacca tttatcactc tatggcctat ggttcgaccc
    15061 acaaatatgt tttgcgaatc attgaccatt ctatgattta cgttgccatt gccggctcat
    15121 acacgcccgt tgtcttgacc ttgatgaata actggtttgg ctatctgatt attgtcatcc
    15181 aatggggaac gaccatcttt ggtattctct ataaaatctt tgctaaaaag gtcaatgaga
    15241 aatttagcct tgctctttac ctgattatgg gctggttggt tctggctatc attcctgcca
    15301 ttatcaatca aacgacaccc gttttctgga gtctcatggt aactggcgga ctctgttata
    15361 cagttggagc tggattttat gccaagaaaa aaccttattt ccacatgatt tggcatctct
    15421 ttatcctagc tgcgtccgta ctccaataca tcgctattgt ttattacatg taaaaaagtt
    15481 gagaaattca atctcaactt ttttctttac acatattgat aaagtactgg tgcaagcgca
    15541 catcatcagt caattctgga tgaaaagaac ttaccaacat atttttttct tgggctgcaa
    15601 caatttgatt gttcactgtt gctagaattt ctacaccctc accaacacta ctgataatcg
    15661 gaccacggat aaaggtcatt ggaatcttgc caactccctt acattctgct tccgtgtaga
    15721 aacttcctaa ttggcgccca taagcattac gctcgaccac catatccata gttcctagat
    15781 gactctcttt ctgagaagtg atttccttag ccagcaaaat taagcccgca caggtcccaa
    15841 acactggtaa gccagataga atggcttctc ggatgggaag tagcatgttc tggtcacgta
    15901 agagcttgcc catggttgta gactcaccac caggcaaaat caaacccgac aagtcactct
    15961 gatcttgctg aaaatcatct agatttctga gttctacact ctcgacacct aattgatcta
    16021 gcacttttgc atgttctgca aaggcccctt gcaaggccaa tattccgatt ttcatctatt
    16081 ttcctcgttc agccatgagg atttggattt cattttcatt aataccaacc atggcttctc
    16141 ctaaatcttc agagatttga gctaggattt gaggattacg gaagttagtc acagccttaa
    16201 caatggcact cgctcgttta acaggatctc ctgacttgaa aatacctgaa ccgacaaaga
    16261 ccccctctgc ccctagttgc atcattaacg cagcatctgc tggcgttgca acacctccag
    16321 cagcgaaatt tacaactggc aattttccat gttcatgaac atattggacc aattctacag
    16381 ggacttgcaa atccttggca gcaacataaa gctcgtcctc acgtaagttt tgaatgcggc
    16441 gaatttcctg attcatcata cgcatatgac gaacagcttg gactatatcc cctgtccctg
    16501 gttctccttt ggtacgaatc atggaagcac cttcagcgat acgacgcaag gcttcaccca
    16561 aatccttagc accacagaca aaaggaactt ggaattcttt cttgtccaca tggaaacggt
    16621 catcagctgg agatagaact tcactctcgt cgatataatc aatttcaata gcctctaaaa
    16681 tctgagcttc aacaaaatgc ccgattctga ccttagccat tactggaata ctaaccgctt
    16741 cttggatttc cttaatcatc tttgggtcgc tcatgcggga aactcctcca gctgcacgaa
    16801 tatcagccgg aattcgttcc aaggccatca cagctgccgc accagcagct tctgcgatac
    16861 gagcctgttc aggattctgc acatccataa taacaccacc cttgagcatc tgtgccaagt
    16921 ttttatttag ttcataacga ttttcagtca tttgttttat cctcatcatt tgtattggta
    16981 gctacctttt cattttaagt cagaacagaa tgaagcacaa gataaaaaaa ctataattgt
    17041 atggggacaa attagctaaa aactatctga ccttaactta aggccagata gctcattcat
    17101 ttttattttt cagccgtaag ggcagccatt gtgatgtagt tgtatggttt gttgaagtgt
    17161 ggcaagaaga agaggtctgt caatgccaat ttatcaattg tcacatgctc ttggatagca
    17221 agtgagaaca tgtggattcc catgctaatt gcaatatcat gtgaaaccat ttgggcacca
    17281 agaatttcac ggctatcttt gtcaaagaca atcttaattg ctacttcatg gttgtcatgt
    17341 ttcatgaatt ctggtttttg aagatcgtta aagcctgttt cagttgcgtt gtaaccagca
    17401 gctttcgctt tttcaagagt caaaccagtt gaaaccatgt gaagaccgta gattgagata
    17461 ccatttgaac cttgaacacc gattccttcc aattcatgtc cacaagcatt gtaggcacca
    17521 acgataccag tgcgaacagc atttgaagca agagcgatat agcttgtatc tttacgagca
    17581 ttgtcataaa cagtcgcaca gtcaccaaca gcgtaaacgc ctgggataga tgtttcttgt
    17641 ttcttgtcta caaggaaggc accgttgcgg aagagttcga tcttaccatc tgcaagggct
    17701 gtgtttggac ggaaaccaac tgcaaggata accatatcca cgtcaaagct ttctttgtca
    17761 gtaatcaagc gttcaacttt accgtcacct tcgattgctt taacagtttg acctagagcc
    17821 aagcggatgt tgtgatcttc caagttcttc gccatcattt gtgtgaagtc tttgtcatag
    17881 taaccgttca agacagtatc aacgatatca acaaggacaa cttcttttcc aagacgttca
    17941 aaggcttcag caagttcaac accgatgtaa ccaccaccaa caacggcgat acggtcgagg
    18001 tgttggctct tgtcagaaag tttattgata acttcttcag cattttggta caatttcacg
    18061 aattgtacgt tttcaagagt tgctttaaat tcgcggtttc ctttaacaat ttcaacacct
    18121 tcgattggtg gcaagattgg tgtagaacct gtagcgaaaa tcaatttttc gtatgattct
    18181 ttgtgctctt ttccttcaac ttccgctgta actactttgt tatcatagtc gattgaaaga
    18241 acaggtgagt tcatgtaaac tttagcacct ttagcttcca atttttcttt atcagaatag
    18301 aacaagcctt cagcaccgtc aatttgttca ccaatccaaa gagccattcc acatcctagg
    18361 aaagagatgt tagagttttg gtcaaataca acaatttcgt tctcatttcc aaaattatcc
    18421 aacatggtat tgatacatgc tgtaccagcg tggttagcac cgactacaac gattttactc
    18481 ataaaaattt cctgccttca ttctaaattt accttactag tataccattt accgttagcg
    18541 tttacaaggg gggtactatt atttcagcat tttttatcaa aaataattcc ccatttatcc
    18601 tgttttcaag cctgatgaat tttatgagca tatttcttga ctttttccaa attttgtttg
    18661 tgaaaattct aactttatgg tattataata acatgaaaat gaaatgtaag ggcttcaatt
    18721 tagatgatta tttgatatta caacttattt tctataagag aaaggagttg gtagcttgac
    18781 tcttcgttca cattctgaac ggctaatggg gactactatc actatttcat tagtggatga
    18841 gcaagccgat atctttctcc aaaaatcctt tgacttgctc aaagaacttg aataccgctt
    18901 caacgccaat agtcaagaat ctgagttgat ggaaatcaat tatcaagcag gaatatcccc
    18961 cgtcacggtt catccagacc tgtttgagct gatttcactt gggttagagc atagcctagc
    19021 gctctctagc cacctcaata tcagcattgg tcccttaatt caaacctggc gtatcggttt
    19081 ttcagatgcc aaggtcgccc agcctcaaga aattgaatcg gtgctgcctc taatcaatcc
    19141 tcatggtatc gagttagatt cttctacttc tactgtgttt ttaaaacaga aaggaatgaa
    19201 aatcgatcta ggttgtttag ccaaaggata cagtgcggat aaggttgccc aatttcttag
    19261 gaaagagggg gtgacttctg ccttgatcaa tctgggaggg aatatcctga ccattggaaa
    19321 aaatcaggca agaggggata acccatggca aatcgggatt caagacccag ccaatcctag
    19381 gggaaatcat ttaatgacca tccctgttgt caataaatct gtcgtaactt caggcattta
    19441 tgaacgtcac ctgaccgtcg atggacaaga ttaccatcac atttttgaca gtcaaacagg
    19501 atatcctgtt gaaacggaac tagcgagtct aacaatcatc tctgataaat cagtcgatgg
    19561 cgaaatctgg acgactcgac tctttggaga aagacctgct tctatcctct ggcaagtcga
    19621 aagtttggag ggcatcgaag tcatcctcat cgataaagaa ggccacctaa gctgttcttc
    19681 aggaattcct actctataga gacaactgtt tcaatggaat tttaaaattg tattatgtaa
    19741 aaagagaaag gaaatctcat gttaaaactt attgctattg ttggaacaaa ttcaaaacgt
    19801 tctacaaacc gtcaattgct tcaatacatg caaaaacact ttgctgacaa agctgaaatt
    19861 gaacttgttg aaatcaaggc cattcctgtc ttcaacaaac cagctgacaa gcaagtacct
    19921 gctgaaatat tggaaattgc tgctaaaatc gaagaggcag atggcgttat tatcggtact
    19981 cctgagtatg atcactctat tccagctgtt ttgatgagcg ctcttgcttg gttgtcttat
    20041 ggtatttacc cacttttgaa caaaccaatc atgattacag gtgcttctta cggtacgctt
    20101 ggttcatctc gtgcccaatt gcaacttcgt caaatcttga atgctcctga aatcaaggca
    20161 aatgttcttc cagatgaatt cttgctctca cactctcttc aagcatttaa cccaagtggc
    20221 gacttggttg accttgatgt tatcaagaaa ttggatgcca tctttgatga cttccgtatc
    20281 ttcgtgaaga ttactgagaa attgcgcaat gcgcaagaat tgcttcgcaa agatgcagaa
    20341 gaatttgact gggaaaattt gtaagatagg agaccgaaag aatgaaattt gttggacttg
    20401 ttggatcaaa ctacgatcaa tcatataacc gcaaactctt ggaatttatc cgtcgcaatt
    20461 tcaaattcaa atttgaatta gaagtacttg aaatcgacga agttccaatg tttaaccaag
    20521 acgaaaaatg ggacgaaagc ttccaattgc gtttcttgta taacaagatt acacgtgctg
    20581 atggtgtcat tatcgccact cctgagcaca accacactat ctcagcttca ctcaaatctg
    20641 tacttgaatg gctttcatac gaagttcatc catttgaaaa caagcctgtt atgattgtgg
    20701 gtgcatcata ctatgaccaa ggaacatcac gtgctcaagt tcaccttcgt aaaatccttg
    20761 atgctccagg tgttaatgcc tacacgcttc caggtaacga attccttctt ggtaaagcta
    20821 aggaagcttt tgataacaac ggaaatatca ccaacgaagg cactgttaaa ttccttgaaa
    20881 cttgcttaga taactttgtt aaatacgtag gagtcgtttc gaaattgaaa aaaccaaaac
    20941 caatcgaatc agaagacttg gattgtggaa aaccaatcgc tacaaccatc acagaagttg
    21001 accctgacga tccagaatgg gtagaaaaag ttgcagcaat cactggtgct gtttctggtg
    21061 atacctatgt caaattggac cacggtatcc taacagttaa ccaaattgat atgttcttga
    21121 aagctatgcc atttgaattg acatacgctg acgacaacaa ccaattcctc tactacaaca
    21181 acgctcacca agatccagac actatgttcg ctaaacgtgt accacctcaa tcaggtagcc
    21241 gtatgtcgac tgttcatggt tctcttccac cagcacgtat gaagaacgta gagtgggtta
    21301 tcggaacact tcgcaacgga aaccaagaat acgtccgtac gatcgttcca ggttctcctg
    21361 caggtgttat caacactcac aactaccaag caatgtacta tcctgatgga tcatacgctg
    21421 gtatcaatga aatcgtcttt aacttccaac catggcttga ctggtaccta aaagagactg
    21481 gtcaacgttt ggtgggtggt agcggaccat ttgctcctgc tgccggaagt catggagacg
    21541 ccgatgctac ttctggcgct tctgattcag gggatgctgg aggccacggt ggtgacgcag
    21601 acgctacagc cggtgcaagt tactaatgat agtttttagg aaccattatg gttccttttt
    21661 tagcgaaaaa agactagcaa acacaaactg ctagtctctt tgttatcgtt tcatctatct
    21721 ttgttaaaag aaagaataca tattatgaat ttggatcatc aagactacgg ccatgtaatc
    21781 ctttttcacg ttgtacttgg cgtagttttt ctggtgtaac atcgtttcct tcttcgtcca
    21841 caattttgat tccttcaatg tggtgacgaa cagcgcggcg ataaccttcg atgtactcct
    21901 cacgtagttt ggcttgttcc actttttctt ctggtgttaa gccttctgtt tttttctttt
    21961 tagcaagctc attgatacga gcaatttttt tcggatccat ttcttctcct ttgtaataag
    22021 ataaagtccg tttatcaaat tttatttagt gttaatttgg ttaaaacaag caaacttagc
    22081 tgctttcttg gttagttgtg acaagattgc caaacgattt tgacggacag cctgatcttc
    22141 agccattacc atagtatttt caaagaaagc atcaatgact gggctaagcg caaagagttg
    22201 tttcaattgc tgacttgcag gtcctgataa aacgagtgtt tctactgctt ctgccaaagc
    22261 tttttcttgg tcattctcaa atagtgctga atcaaccgta gcaacccctt ctgccttctc
    22321 agccaggtta aaggcacgag aaagtgattc aacagatggt ttaaaatctt cttccttgct
    22381 tacttctacg agagcacttg ctgcttccaa catatctgcc acaacaaagt ttgaacctgc
    22441 aagaactgct tctttgatat cttttggagt agagcccatc atcttatcaa cacgagcctt
    22501 gataaagtcc ataacctctg ctttattttc ataagtcaaa ctgtcaaatt tcaatgcata
    22561 aaggctatca atcagctcat ccatagcaat gtgccaacca aaggcatcca agatacgaac
    22621 cacaccttga gttgcacgac gaagggcata agggtcatta gaacctgatg gaatcaatcc
    22681 tactgagaag aaactcaaaa tcgtatccaa tttgtctgca atggctagaa ctgcgccgac
    22741 cttgctctct ggaagttctc cttcagctga tgtaggcatg tagtgttcac gaatagcagc
    22801 tgccaccgct ggagtttcac cagcaagaag ggtgtatttt tcacccataa ttccttggag
    22861 ttcgtcaaat tcaccaacca tacctgtcaa caagtcaaac ttgtaaatgg ctgctgcacg
    22921 agcaaggtca actgtttcat ccactgacaa accagctttt tctgccaaaa gtacagtgat
    22981 ttgacccgta cgaatcatgt gttcacgaag ggaaccaatc ttctcatgga aggtgacatt
    23041 gtttaatttt tcaacaagat ctgaaatcac caatttttgg tcttcacgcc agaagaattc
    23101 tccgtcttcc aagcgggcta ccaagacttt ttcatttcct ttgatgacat ttttcaaacg
    23161 ctctgcgttt ccgttacgaa cagaaatgaa gtttggcaag agttttccat cttgatcacg
    23221 aacaacaaag taacgctggt gttccttcat agaagtcacc aagacttctt ctggaacttc
    23281 aaggtattta gcatcaaaac ttcccatgaa ggcagttggg tattcaacca aattcaagac
    23341 ttcattcagc aaatccgcat caatttcgat atgtacacca tgttttgcct caatttcctt
    23401 gatttggtca acaatcattt gctcacgttc acatggatct gcgattacaa actgcttacg
    23461 aaggtcttct tcatagctca atgctgactg aattttggtt tctttcccca agaaacgatg
    23521 gccacggctc acacgacttc ccttgatatc aaggaaatcc aagtcaaact cttgctcatc
    23581 caagagaaca gttaaagtgt gaacagggcg gatgtattca aagctatttc cagcccagtg
    23641 catgctgaca gggaaagtca atgacttcaa gacatctaca acaccaggaa caatggcttc
    23701 aactgattgg ccaacttctt ccttagtgac atagacatat tcttcaccct tgatttcacg
    23761 gaattcgata tcttcaacag tcaaaccttt cccacggaca aatccttgag ctgctttggt
    23821 gaagtttcca tcactatcca aggcaatttt ctttgctggt cccttgaaat cttctgtcaa
    23881 atcagactgt ttgtctgata aaccagtcac acgaacagcc aaacgacgtg gtgttgagaa
    23941 ggtttgaatg gcttcaaaag acaggcggtt ttccttgagg aaggctgcca ttttttcgcc
    24001 tagttgtttt tcacttggtg tgacaacata ggctggtaat tcttcaagac cgagttctac
    24061 taataagttt tttgtcatgt tttttccttt acattttctt caatcttttt tgatatgcac
    24121 cttaggtact ggggacgtcg ctaactaact ctgtgagtct gtatggaaat ccaatgctaa
    24181 atttatcaag atttccaaca atctcatcaa agtggattta gctgactgat ttttgaacct
    24241 aaggtttcaa aaatccccac ataacagtac ggcggtgcat atccctctag caagtcttcg
    24301 acttgcctct aacgatttta gagtacagta ttactcacta ttctgcgtct tctgctaaaa
    24361 gtttaactcg tgtttcttca tccaaaagtg ggtaacctag gcgtttgcgt tctgcaacaa
    24421 aggttttggc tacaacacgg gccaagttac ggatacgagc gatatagcct gcacgctctg
    24481 ttacagatac ggcaccacgc gcgtcaagca gattaaaggt atgtgaacat ttgagaacat
    24541 agtcataggc agggtgtacc aagccttctt ctaatgcacg accagcttct ttttcaaact
    24601 tatcaaagtt ttcaagcaac atttcttggt ccgaaatttc aaatgaatat tttgagtgct
    24661 catactcagg ctggataaag atttctccgt attttacacc atcagcccac tcgatatcat
    24721 agacagagtc tacttcttga atgtaagaag ccaagcgctc caaaccatag gtaacttccg
    24781 cagtcacagg gccagttgcc aatccaccga cttgttggaa ataagtgaac tgagtgattt
    24841 ccattccgtc aagccaaact tcccaaccaa gaccagctga accagttgat gggttttccc
    24901 agttgtcctc aacaaaacga atatcgtgct ccaaaggatt gattcccaat ttttccaaag
    24961 attcaaggta aagttcttgg atatttgatg gagaaggctt catgaccacc tggaattggt
    25021 ggtgttggta gagacggtta gggttttccc cataacgacc gtcagcagga cgacgtgatg
    25081 gctctacata agctgcattc catggctcag gtccgatagc acgaaggaaa gtgtaaggac
    25141 tcattgttcc cgcacctttt tcattatcat aagcctgcat aagcatacaa ccttggtcat
    25201 tccaaaattg ttgcaaagta aggatgattt cctggaaagt caatttctta gacattgttt
    25261 actccttttt atataaatta cttgcgacat gagtctgcct cgtcgatcat acgaggcaag
    25321 acgagttagt actgcgtcta gctcaggcac tctagtgctg agcgtggggc agtccgactg
    25381 taaggaggtt tctgccactg acgcagtgaa atgtcaattt cttagacatt gtttactcct
    25441 ttagttttta tatttctttt tcaattaatt tctgctgaac aaaccaatct aacaagggaa
    25501 aagttttttc tgtatttgcc cataaatgat aagaatctaa gaccgcttgt acactaccta
    25561 aattttctac caacttatct actgtcaaaa agctgcgcca gtattcataa aaaatacttg
    25621 catagttctt atcataagtc gaagaaccaa aatcattcaa tgaatgccaa ccatacttct
    25681 tctgaaaaag ttctacgaga gattgattac aaattttttc cgcttgaaat tcctcttctg
    25741 tcaagaaata cttgcgacta atatattcaa ccatcccctc ttcgaaccag atataagagt
    25801 cataaccatc aaaatcatct aaaaaatgct ccgaccaatg agctaactca tgtcctacaa
    25861 tctgtaagag gaaattttca gataaagaat gatagtgact ttctattgct tgagtttgct
    25921 gagaacactc gtagtccatc aattgataca aatacaactc tttccaaaca gctaaatcag
    25981 gcgccataac cattcgtcta ttatttgtat aggctggaac agcgctttcc ctaataatct
    26041 gtgtagcagc attaaaatct gaccaaataa cggcttgcgg taaatcacag actgcaagtt
    26101 cattctttaa aaaagattga taatctttca acttttcagt atttcttact acaaaatcac
    26161 gaaatgtagc tagttgacta tcgtctttta caagataaag gttgtccacg gctctccttt
    26221 ctttcacaca atagactgaa taagcaaaag aaccgcgtcc gacaatccta ggttgattta
    26281 acctaggggc gtcagaaacg cggttccacc ctaatttatt acttcattgt ttttgaaaat
    26341 actacagaaa gcgccagctc attattttgc cctacttggc tcccactatc ccaagctcgc
    26401 ttgaagaacg ccataagact ttctttcctg ctgactatta tatcaaaaat tagaataatg
    26461 tacaattctt tttatgattt tctagaaatc cacatcatca actcgtggag cacccgattg
    26521 aacagcaatc gtttttaagt tttctctctc ctcatgactc agttcaattc caaagcaatc
    26581 aagattagct tgaatacgag aggttgtgac agattttgga agtggtaaaa atccttctgc
    26641 caagctccag gccaaggcta tctgagcaat cgattttccg tgatttgctg cgatttcttg
    26701 cacttgcttg ctatcaaata gttctccctg accaaaaggc ccccaagctt ccaataaaat
    26761 tcccttttca cgacagtaag ctacgacttg atcttgatac acacctggcg ccaagcgaac
    26821 ttgattgacc gcaggaacga tagttgcagt ttcaagcaag gcatccaaat gatggggaag
    26881 aaaattgcta acgccgatag cacggatttt cccttcttga tagaggtctt ccatcgctct
    26941 ccaaacttcc gcattgcgag ttttccatgc gtcattttct ctgagcggtt ttgggttcgg
    27001 ccaatgaatc aaatacaaat ccaaataatc caagcccagt ttttctatag atttttccaa
    27061 agcttgacga gtttgctcat aggtttgctg actattccaa agcttggtag ttacgaacat
    27121 ttcttcacgt ggaactccgc tatctttgat tgcttgacca acactttttt cattctgata
    27181 aatcgccgcc gtatcaatat gacgataacc agccttcaag gcttctaaca ctgcacgata
    27241 ggcttcttct ccatccttag ccttaaaagt tccaaatccc aatactggaa tttctactcc
    27301 attatttaat tgataggtat tcatatgctt ctccttctat tttattcatc aattatagca
    27361 taaaacattt tttaagtagt actatcttct gtaaaaaata agtctgtcaa atatctaaca
    27421 gacctatttt ttcttgctta ttcatcacga ctatagtaca gctcatgagc ttttaggcga
    27481 gtattgagca tctctggtat ggtcacaaag gtataacctt gatttttcaa atactcaatg
    27541 acccttggca aggcattgac tgtcggactg tgaatatcat gcatcaaaac gatagagccg
    27601 ttagctactt gatgctgaat ttctgtcaaa atagatgctt catttttact cttccagtcc
    27661 agactatcca catcccacat gataaagctc aaatccaagc tattgcgaat atcatctgta
    27721 atagcaccat aaggtggacg catgagttta gaactagaac ccagcacttt agttagcaca
    27781 tcctcagtat cagtaatctg ctttttagct tcatcaagag agagttgcga gagaatcgga
    27841 tggctccaac tatggtttcc aacaacatga ccttcagatt ttatcctctt caccaagtcc
    27901 tcattcccag aaacattttt cccaagcaca aagaaagtcg ctttaatatc atatttagct
    27961 agggtctcta atacctgcgg ggtcgttgct ggatttggac catcatcaaa ggttagagcg
    28021 acaacttttt gatatttctt atcaaagtaa gattggtaca aggccgcatc tttttcgagt
    28081 aagtacgaag attggataac atcaaagaaa gcagatactg gcaaggctat ctcttctaaa
    28141 ttttcaacca caggacttgg ataaaggata atctgactat ccttgtaatc aaaattccat
    28201 gcagacaagt cttggtcaga gaagtttttt acaatctgct cactctggtc ttgctctatt
    28261 tttttatcct ctatgaagga ggtcaactct tttatcagct gttccttagc cttactagca
    28321 tctgaaaaca gttggtcaag tgtaaaaggt tggccatctt ctgttaagtg aacctttcct
    28381 agactggtct tttcagtctc ttcaacctta aaagcaacta aatcatagat ttgtttggtc
    28441 acattacgat taacgactcc ctttaaacct gactcttctt gctctgtata gtagaaaaca
    28501 agattgtcct tactttctag cttgtcctta acatcttgat ttatcaactc cctaacagag
    28561 gaaatcactt tctccccttg gagaggataa taggcaatca cttcggcttg cccctgacga
    28621 aaatgctcct tctgatttcc ctcactcaat tgatcatctt tctctttttt gagcgattca
    28681 atcttttgct caaaactttt ttgctggtag atcttaaaag caataaatcc gcctaatagg
    28741 caaatagaaa ttgctaaaat accaatcaaa gccaataata catgtctcgt tttcccgtgt
    28801 ctgccacgtc ctagtctact tttattcata tttatatcat aacaaatttg agcaataatt
    28861 tcaatgatac aatttggcaa tccacaattc ctctagcaag ccaaagcatc ttacatcaac
    28921 tccaacatcc gtatctgtag agattatgta gttttctatc tatggaattt ctagtagatt
    28981 gaagctagaa tagtagacct atacttctaa aacattgtta gaaatcgatt tgattgtcct
    29041 gatcgatttg tcctgttctc atttcatttt actataaaac tatgaaaagc taggtcatct
    29101 gagaagtaat tactatcgac aattgcgata gcgtatactg gtgcgatttg tttgtagctc
    29161 tggtgggtat caccttcacg ttggcgaatt ttttctaggt tttgattaac ctgactgcac
    29221 agataagccc ataggcgatt gatgaaaaaa ttctgatgat gaacctgaat ttcgatgata
    29281 acttggattc cattatctaa ctccgccaag acgtctatac tagtatagaa atcttgcgct
    29341 gagtagggca tggaaggcaa gacgtgaatg ttacttccct ccaaaatcgt cacatttttt
    29401 gctggcaagt ccagcatatc gcggataaat tgacaaatca ttagttgggc tgatacctgg
    29461 atgtctgaga atcctccttt tcctccttct attatagcac atttttaaat ctaggtttgc
    29521 tagattctat gcttctatct atttattcgg aaaagaaagc taatagctta tttgaaattt
    29581 tctcctctct gttggatagt cccgtctatc tatgttataa tgaaagaagg atttaaaatc
    29641 ggaaaaggag tatttatgct aaaattaggt gtcatcggaa ctggcgctat cagccatcat
    29701 ttcatagaag cagcccatac cagtggagaa taccaactgg tcgcaatcta ttctagaaaa
    29761 ctagaaactg cagcaacctt tgcttctcgc tatcagaata tccaactatt cgatcaatta
    29821 gaagtcttct tcaaatcttc ttttgattta gtctatatcg ccagtccaaa ctccttacat
    29881 tttgctcagg caaaagctgc cttgtctgct ggtaaacatg ttattctcga aaagccagct
    29941 gtcactcaac cacaagaatg gtttgatttg attcaaacag ctgaaaaaaa taactgtttt
    30001 atctttgaag cagctcgtaa ttaccacgag aaagccttta ctactatcaa aaacttttta
    30061 gcagataagc aagtgttagg agcagatttc aactatgcca aatactcttc caagatgcct
    30121 gacttgttgg ctggacaaac accaaatgtc ttttcagacc gttttgctgg tggagccctc
    30181 atggatttgg ggatttatcc cctctatgct gctgttcgtc tttttgaaaa agctaatgac
    30241 gcgacttacc atgctcaaca gcttgacaat agcattgacc taaatggaga tggtatcctc
    30301 ttctacccag actatcaagt tcacatcaag gctggaaaaa acatcacttc caatcttcct
    30361 tgcgagattt atacaacaga tggaaccttg actctcaaca cgattgagca tattcgctca
    30421 gctattttta ccgaccacca aggaaatcaa gtccagcttc ctatccaaca ggctcctcat
    30481 acgatgactg aggaagtcgc tgcatttgca cacatgatcc agcaaccaga tctgaatctc
    30541 taccaaactt ggctgtatga tgcaggctct gttcatgagc tactatatac catgcgccag
    30601 actgctggca ttagatttga ggcagaaaaa tgaaaaccaa actaccgact gaatggcaag
    30661 aactgagtga ccaactcggt ttccaagaat tcacccccat tcaaactcaa ctatttgagc
    30721 cccttcttgc tggagaaaac ctcctaggag tgagccaaac cggaactggt aagaccctag
    30781 cttatctcct accaagtctt ctcagactac aaaagaaaaa agcccaacaa ctcttgattc
    30841 tagcaccaaa tacggaactt gctggacaga tttttgatgt atgtaaaacg tgggcagaag
    30901 ctatcggatt gactgctcaa ctcttccttt caggttcaag tcagaaacga caaattgaac
    30961 gtcttaaaaa ggggccagaa attctgattg gaactcctgg ccgtatcttt gaactcatta
    31021 aacttaaaaa aatcaagatg atgaatgtgg aaaccatcat cctggatgaa tttgaccaat
    31081 tactagatga ttctcagatt cactttgtag aaaaaatcac tcactacgca cctcgtgacc
    31141 accaactggt ctacatgagt gccacgacca agtttgatca agaaaagatt gtaccgaata
    31201 cacgcactat tgatctctct gatcaaaaat tggacaatat ccagcatttc tacatgcagg
    31261 tagaccaacg tcatcgagtg gatatactac gaaaactggc tcatgtagag gatttccgtg
    31321 gtctagtctt cttcaatagc ctgtcagacc ttgggaatgc cgaggaaaaa ctacagtatc
    31381 gtgatatatt ggctgtttcc ctcgctagtg atgttaatgt taaatttaga aaagtcatct
    31441 tagaaaagtt taaagataac caactaaccc tgcttcttgc aactgacctt ttggctcgtg
    31501 gaattgatat cgatagccta gaatgtgtcg taaactttga tattcctaga gatagcgaaa
    31561 cctacacaca ccgtgctggc cgtactggcc gtatgggcaa ggaaggatat gttattactc
    31621 tcgtcactca tacagaagaa atcaaaaaac ttaaaaagtt tgcaagtatc cgagaaattg
    31681 tcctaaaaaa ccaagaactc tatatcaaat aaagccccat tgctctatac acatccagtg
    31741 tatggagctt ttttacaagc aattcaattt tatactcatc tgttttcaaa aagcattcta
    31801 atccatctcc gattaacgat ggactttatc acctccttct ccagttcttg tataa
//
LOCUS       DAVHSY010000022        30680 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.022, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000022 DAVHSY010000000
VERSION     DAVHSY010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30680
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.022"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            151..804
                     /locus_tag="VVR43_001236"
     CDS             151..804
                     /locus_tag="VVR43_001236"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU6149600.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            814..1278
                     /locus_tag="VVR43_001237"
     CDS             814..1278
                     /locus_tag="VVR43_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU6149601.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECATREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1291..2559
                     /locus_tag="VVR43_001238"
     CDS             1291..2559
                     /locus_tag="VVR43_001238"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU6149602.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFKAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2573..2833
                     /locus_tag="VVR43_001239"
     CDS             2573..2833
                     /locus_tag="VVR43_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149603.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2844..4205
                     /gene="pdrM"
                     /locus_tag="VVR43_001240"
     CDS             2844..4205
                     /gene="pdrM"
                     /locus_tag="VVR43_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU6149604.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4359..5327
                     /locus_tag="VVR43_001241"
     CDS             4359..5327
                     /locus_tag="VVR43_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU6149605.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5343..6335
                     /locus_tag="VVR43_001242"
     CDS             5343..6335
                     /locus_tag="VVR43_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU6149606.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6553..7596
                     /locus_tag="VVR43_001243"
     CDS             6553..7596
                     /locus_tag="VVR43_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU6149607.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYKVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7660..9345
                     /gene="lpdA"
                     /locus_tag="VVR43_001244"
     CDS             7660..9345
                     /gene="lpdA"
                     /locus_tag="VVR43_001244"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU6149608.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9409..10398
                     /locus_tag="VVR43_001245"
     CDS             9409..10398
                     /locus_tag="VVR43_001245"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU6149609.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAKINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10471..11541)
                     /gene="xerS"
                     /locus_tag="VVR43_001246"
     CDS             complement(10471..11541)
                     /gene="xerS"
                     /locus_tag="VVR43_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU6149610.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(12035..13585)
                     /locus_tag="VVR43_001247"
     CDS             complement(12035..13585)
                     /locus_tag="VVR43_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU6149611.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALIGAICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(13601..14380)
                     /locus_tag="VVR43_001248"
     CDS             complement(13601..14380)
                     /locus_tag="VVR43_001248"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU6149612.1"
                     /translation="MATIKEIKELLVTVKELESPIFLDLEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(14367..15218)
                     /gene="ylqF"
                     /locus_tag="VVR43_001249"
     CDS             complement(14367..15218)
                     /gene="ylqF"
                     /locus_tag="VVR43_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU6149613.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LIKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15438..15614)
                     /locus_tag="VVR43_001250"
     CDS             complement(15438..15614)
                     /locus_tag="VVR43_001250"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6149614.1"
                     /translation="MQAGIPPDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(15666..21680)
                     /locus_tag="VVR43_001251"
     CDS             complement(15666..21680)
                     /locus_tag="VVR43_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6149615.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLVELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTKLINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEPSNGN
                     STEDVSTESNTSNSNGNEEIKQENELDPDKKVEEPEKKLELRNVSDIELYSQTNGTYR
                     QHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNGQSVYKITAKAEKLQQEL
                     ENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTYHLAASLNANEVELGPDE
                     RSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEKLSLKNVAISGKDDIGSL
                     ANEAQNNTKIKQVHVDGVLAGERGIGGLLAKAEQSSITESSFKGRIINTYETTAAYNI
                     GGMVGHLTGDKALLTKSKATVAISSNTNTSDQTVGGLAGLVDRDAQIQDSYAEGDINN
                     VKHFGRVAGVAGNLWDRTSGDVRYAGSLTNVLSDVNVTNGNAITGYHYNEMKVKDTFS
                     SKANRVYNVTLVKDEVVSKESFEERGTMLDASQIASKKAEINPFILPTVEPLSTSGKK
                     DSDFSKVAYYQAKRNLTYKNIEKLLPFYNKATIVKYGNLVNENSLLYQKELLSAVMMK
                     DNQVITDIVSNKQTANKLLLHYKDDLSEKLDLKYQNDFAKLAEYSLGNTGLLYTPNQF
                     LYDQTSIIKQVLPDLQKVDYHSEAIRKTLGISPNVKQTELYLEDQFAKTKQQLEDSLK
                     KLLSADAGLASANPVTEGYLVDKIKRNKEALLLGLTYLERWYNFSYGQVNVKDLVLYH
                     LDFFGKGNASPLDTLIELGKSGFNNLLAKNNVDTYGISLASQHGTTDLFSTLEHYRKV
                     FLPNTSNNDWFKSETKAYIVEEKSTIAEVKAKQKQAGTKYSIGVYDRITSNTWKYRNM
                     VLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALNDFVEENARETAKRQRDH
                     YDYWYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEAKFDSSNPAMKNFFGPVG
                     NKVVHNQHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRSGLGP
                     EFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVLDPTERFQNAADLQNYVH
                     NMFDLIYMMEYLEGQSIVNKLSVYQKIEALRKIENQYLTDPADGNDVYATNVVKNLTE
                     DEAKKLTSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAPIFSALSGEKGTPGDLMG
                     RRIAFELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGKERGLVTDELVLKKVFDG
                     KYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPRYGTKTINNVDELQKLMDEAVL
                     QDATGTRWSNYNPETDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK"
     gene            complement(21889..23067)
                     /locus_tag="VVR43_001252"
     CDS             complement(21889..23067)
                     /locus_tag="VVR43_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149616.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(23282..26932)
                     /gene="addA"
                     /locus_tag="VVR43_001253"
     CDS             complement(23282..26932)
                     /gene="addA"
                     /locus_tag="VVR43_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU6149617.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVTFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(26929..30204)
                     /gene="rexB"
                     /locus_tag="VVR43_001254"
     CDS             complement(26929..30204)
                     /gene="rexB"
                     /locus_tag="VVR43_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU6149618.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RFYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDIDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDSFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDIERDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            complement(30404..30559)
                     /locus_tag="VVR43_001255"
                     /pseudo
     CDS             complement(30404..30559)
                     /locus_tag="VVR43_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT         8572 a         6135 c         6358 g         9615 t
ORIGIN      
        1 aattataaaa aatagccagt ctttataaac tgtattcacg tattcaaatc gtatatagtc
       61 gatttattaa atctttagat aaattgtaaa aagtggtttc catagccact ttttgctata
      121 atagaggcag taaaaatgaa ggagtcagct atggaacact cgtcttggca tgctttgatt
      181 aaggcgcaat tacctgaggg ttatttcggg aaaatcaatc agtttatgga gcaggtctat
      241 tctcagggga ttatttatcc acccaaggaa aaggtttttc aggctctctt gacaacactg
      301 cttgaagaag ttaaggtggt aattctaggg caagacccct atcacggacc aggtcaagcg
      361 cagggcttga gtttttctgt acctgactct atcccagctc caccatcctt gcaaaatatc
      421 ttgaaagaat tgtcagatga tatcggagtt aagaaatctc atgatttgac agcttgggct
      481 gagcaaggag tcttgcttct taatgcttgt ttgactgttc ctgctggaca ggccaatggt
      541 catgctggtc aaatctggga gccttttact gatgctgtga ttcaggtggt caatcatcta
      601 gatagaccag tcgtttttgt actctgggga gcttatgcac gtaagaagaa ggccttagtt
      661 accaatcctc atcacttgat tatcgaatca gcccatccaa gtcctttgtc ggtttataga
      721 ggattttggg gttccaagcc cttttccaag gccaatgcat tcttaaaaga gacaggacaa
      781 gagccaatcg attggcttag ataaggagaa aatatgcctc agttagcgac gatttgctac
      841 attgataatg ggaaagaact gctcatgctc catcgtaata agaaacccaa tgatgtccat
      901 gaagggaaat ggattggtgt gggtggtaag ctagagagag gagagacgcc ccaggaatgc
      961 gcgacgcgtg aaatccttga agaaacaggg ctcaaagcca agccagttct aaaaggtgtc
     1021 atcacttttc ctgaatttac accagattta gactggtaca cctatgtttt taaggtgacg
     1081 gagtttgagg gcgacttgat tgactgcaat gaggggacgc tagaatgggt tccctatgat
     1141 gaggttttga gcaagccgac ttgggaaggt gaccacacct ttgttgagtg gcttttagag
     1201 gataaaccct tcttttcagc caagtttgtt tatgatgggg ataaattgtt ggatacccaa
     1261 gttgatttct atgaataaag gagaaagcag atgctactaa tcaaaaatgg tcgtgtaatg
     1321 gatcccaagt ctggtttgga tcaagtttgt gatgtcttag ttcaagatgg gaaaattatc
     1381 aaaattgcgc ctgagatcac ggaagaagga gcagaaacga ttgatgctac tggtcttgtg
     1441 gttgctcctg gtttggtcga tattcatgtg catttccgtg aacctggtca aacacataaa
     1501 gaagacattc atactggtgc cctagcagcc gctgcaggtg gttttactac tgtcgtcatg
     1561 atggctaata ccagtccaac catttcagac gtggagactt tgcaagcagt tctccagtca
     1621 gctgccaaag agaagattaa tgtcaagaca gttgcgacca ttactaaaaa ctttaatggt
     1681 aaaaacttga ctgactttaa ggcactctta gaagctggtg cggttggttt ctctgatgac
     1741 ggtattccgc ttgagagcag taagattgtc aaggaagcca tggaggaagc caaaaaactc
     1801 aataccttta tcagccttca tgaggaagat ccaggtttga acggtgttct tggctttaat
     1861 gaaaatattg ctagagaaca tttccatatc tgcggtgcta ctggggtggc tgagtacgct
     1921 atgatggcgc gtgatgtcat gattgcctat gcaactaaag cccatgttca catccagcat
     1981 ttgtctaagg aagaaagtgt taaagtagtg gagtttgctc aggggttagg tgcagaagtc
     2041 acagcagaag tagcgccaca gcatttctct aagacagaag cacttctttt aacacaaggt
     2101 agcaatgcta agatgaatcc accgcttcgt ttggaatcag accgtcgtgc cgttatcgaa
     2161 ggtctcaaat caggtgtcat cacagttatt gcgactgacc acgcgcctca tcatgtagat
     2221 gaaaaaaatg ttgaggatat taccaaagcg ccatctggta tgactggctt agaaacatcc
     2281 ctgtctctcg gcttgaccta tttggtagaa gctggtgagt tgagcttgat ggaattactt
     2341 gaaaaaatga catacaaccc agccaagctt tacaacttta aagcaggtta cttggctgag
     2401 aatggtccag cagatatcac tatttttgat gccaaggctg accgccttgt ggactcccat
     2461 tttgcttcca aagcagctaa ttcaccattc atcggtgaaa ccttaaaagg gcaggttaaa
     2521 tataccatct gtaagggaca aatcgtctat caagcttgat aggagttaga atatgaatta
     2581 ttttcgaaaa cgtagggaga gacaagcgaa atctaatagt ggaatttact gtcctgcagc
     2641 taatcgttcc aaaattcaat atgaaactaa agaaaaagct gaccatgcgg ttcaatatga
     2701 taacggaggt ttagttagaa gctattattg tcgtacatgt gcgtgttggc atactacttc
     2761 aaaatctaat aaacctccgc taagtttgaa aaactatggt ctgaaactct ttggtttaga
     2821 taaatcagaa tagaaagaga agtatgtata agacaaagtg tttacgagag aagttggtat
     2881 tatttttaaa aattttcttc ccaatcctga tttaccaatt tgccaattat tctgcctctt
     2941 ttgttgatac tgcaatgaca ggtcaataca acactatgga cttggctggt gtatctatgg
     3001 caaccagtat ctggaatcct ttctttacat ttctaacagg gattgtgtca gccttggtgc
     3061 ctatcattgg tcaccatctt ggtcgaggaa aaaaggaaga agttgcgtct gatttttacc
     3121 aatttattta tttggccttg ggcctatctg tggtcttgct ggggatggta cttttcttgg
     3181 caccaacaat cttgaatcat attgggttag aagcagcagt agcggcagta gcggttcgct
     3241 atctttggtt tttatctatc gggattatcc ccttgttgct ctttagcgtc attcgttcct
     3301 tgctggattc gctgggcttg accaaactgt ccatgtacct catgcttttg ttactccctc
     3361 tcaatagcgg atttaactat ctcttgattt acggtgcctt tggtgttcca gaactgggag
     3421 gggctggtgc tggtttagga acatccttgg cctactgggt cttgcttggg atttctgttc
     3481 tggttttatt taaacaggag aagctcaaag ccttacacct tgagaaacga attccactta
     3541 atatggataa aattaaggaa ggagttcgtt taggtctgcc tattggggga actgtcttcg
     3601 cggaagtggc tgtcttttca gtggttggct tgattatggc taagttttcg tccttgatta
     3661 tagctagtca ccagtcagct atgaactttt caagtcttat gtacgccttt cctatgagta
     3721 tctcatcggc tatggctatt gtcgtttcct atgaagtggg agccaagcga tttgatgatg
     3781 cgaaaaccta tattggtcta ggaagatgga ctgccctcat ttttgcggcc ttcaccttaa
     3841 ccttccttta catttttagg ggaaatgtgg ccagtcttta tggtaacgac ccaaaattta
     3901 tcgatttgac agtgcgtttt ttaacttata gtcttttctt ccagttagca gatacctttg
     3961 cggcgccgct tcagggaatt ttgcgggggt ataaggatac agttattcct ttttaccttg
     4021 gtttgcttgg ttattggggc gtagcaatcc ctgtggctac gctatttgat tccctaacag
     4081 attttggagc ttattcttac tggatcggct tgattattag tttgattgtg agcggggcgc
     4141 tctaccgttg gcgtttaact gtgattatga agagatttga atctttagca aaatccaaac
     4201 gctaaaaagt ttgtgaaaaa atattcttga caagaaaatc ccttgttttc acggggtttt
     4261 cttttttatt ttgtgaaatt tcttttagaa aaactttgac agtatttgcc aaaagcggta
     4321 aaatagtaag gtaagaagaa agttagaaag gcaagaagat gtcaacttta gataaaaatc
     4381 ttttgctaga aatgttccgt aagatggaag aaatccgtcg catggactta aaaattgcac
     4441 aattagtaaa gaaagggaaa gtgccaggaa tgacgcactt ttctgttggt gaagaggcag
     4501 ctaacgtggg ggctatgtta gctctcaatc cagatgatct gattacctca aaccaccgtg
     4561 gacacgggca agctattgct aaagggattg acctcaacgg aatgatggct gaaatccttg
     4621 gtaaatacac tggaacctgt aaagggaaag gtggatctat gcatatcgct gaccttgatg
     4681 ctgggaacct tggtgccaat ggtatcgtag gtggtggtat ggggatcgct gtcggtgcag
     4741 ccctcagtca gcaaatgcaa aataccggta aaatcgttgt ctgcttcttt ggagatggtg
     4801 cgaccaatga aggtgttttc cacgaagcag tgaacatggc ttctatctgg aacctgccag
     4861 tcattttcta ttgcattaac aacggttacg gtatctctgc ggatatcaag aaaatgacca
     4921 atatagaaca tatccatcaa cgtagcgccg cttatggaat tcctggaatg ttcatcgaag
     4981 acggtaacaa tgtcatcgat gtctatgaag gatttcagaa agctgtagac catgttcgca
     5041 gtggcaatgg tccagtcttg attgaaagtg taacttatcg ctggctcggt cactcatcat
     5101 ctgaccctgg taaatatcgt acgcgtgaag aagtggaatt gtggaaacaa aaagatccaa
     5161 tcgaaaacct ccgcaattac cttattgaaa ataacattgc aagtgccgaa gaattggaag
     5221 aaatccaagc gcaagtaaag gaagcagtag aagcttctgt taaatttgca gaggaaagcc
     5281 cattcccacc gcttgaatca gcctttgaag atatttacgc agactaagga gaaagagata
     5341 aaatggaaac aaaaacaatg tccttccgtg acaccattat ccttgctatg tctgaggaaa
     5401 tgcgtcgcga tgaaaatgtg ttcttgatgg gagaagacgt cggtgtcttc ggaggagact
     5461 tcggtacttc tgttggaatg cttgaagaat ttggtccaga acgtgtccgt gactgtccga
     5521 tttctgaagc tgccatctct ggagcagcag caggagcagc catgacagga cttcgtccaa
     5581 tcgtcgatat gaccttcatg gacttctctg ttattgccat ggacaatatc gtcaaccaag
     5641 ctgctaaaac acgttacatg tttggtggta aaggtcaggt tccaatgact gttcgttgtg
     5701 cagctggtaa cggagttggc tctgccgccc agcactcaca atctctagag tcttggttta
     5761 ctcacattcc aggacttaag gttgtggcac ctggaacacc tgcggacatg aaaggcctgc
     5821 ttaagtcttc tatccgtgat aacaacccag ttattatact tgagtacaag tcagaattta
     5881 accaaaaagg ggaagtgcca gttgatccag actacacaat tccacttggg gttggtgaaa
     5941 tcaaacgcca aggaacggat gtaacagttg ttacttatgg aaaaatgctt cgccgtgtgg
     6001 ttcaagctgc tgaagaatta gcagaagaag gaatttcagt tgaaattgtt gacccacgta
     6061 cccttgttcc gcttgataag gatatcatca taaactcagt gaagaagact ggtaaggttg
     6121 ttctggtcaa cgatgcccac aaaacaagtg gctatatcgg tgaaatttca gctattattt
     6181 cagaatcaga agcatttgac tatctagatg caccaattcg ccgttgtgca ggagaagatg
     6241 tgccgatgcc ttatgcacaa aacctagaaa atgcaatgat tccaacagtt gaaagtatca
     6301 aagatgcaat ccgaaaaact tataacaaag aatagagtta cataagataa gttatgtaaa
     6361 taaaataaag ctgacgagaa actttgtatc ttttaggtgc agagctcttc gtcattaata
     6421 tcttagatta gagcacgggc taaaagctcg gaaaaaagat aaatctcctt ggcttcatcg
     6481 aagccatcgt cgatttccta tttttcagtc gcttttgacg ccctttgtat cataaataga
     6541 attggagagg tcatggctga tgacaagcta agagcgactc ctgcagctag aaagttagcg
     6601 gatgatttag ggataaacct ctacgacgtt tctggctcag gtgcaaacgg tcgtgtccac
     6661 aaagaagacg tggaaactta taaagacaca aacgtggttc gcatttcgcc acttgcaaaa
     6721 cgaattgccc tcgaacataa cattgcttgg caggaaatcc aaggaaccgg tcatcgtggt
     6781 aaaatcatga agaaggatgt tttggccctg cttcctgaaa atatcgaaaa cgatagcatc
     6841 aaatctcctg ctcagattga aaaagtggaa gaagtccctg ataacgtaac accatatggt
     6901 gaaatcgagc gtattccaat gacaccaatg cgtaaggtta ttgcccaacg catggttgaa
     6961 tcttacttga ctgcgccaac cttcaccctc aactataaag ttgatatgac tgaaatgttg
     7021 gctcttcgta agaaggttct tgagccaatc atggaagcaa ctgggaagaa gactactgta
     7081 acagaccttc tttcgcttgc agttgttaag actcttatga aacacccata catcaacgct
     7141 tcattgacag aagatggcaa gactattatc actcacaact atgtcaatct tgccatggca
     7201 gttgggatgg ataatggatt gatgacacct gtcgtttaca atgctgagaa aatgagtctt
     7261 tcagaactgg ttgtagcctt taaggatgtt attggccgta ccttggatgg taaattggct
     7321 ccaagtgagt tacaaaattc aacattcaca atcagtaatt tgggaatgtt tggtgttcag
     7381 tcctttggtc cgattattaa ccaacccaac tcagctatcc ttggtgtcag ttcgacaatc
     7441 gagaagccag ttgtcgtcaa tggtgaaatt gtgattcgcc caatcatgag tttaggatta
     7501 accattgacc accgtgtcgt agatggtatg gctggtgcta agtttatgaa ggacttgaaa
     7561 gagttgattg aaacgccaat ctcaatgtta atttaagagc aagagtattc atttttaaga
     7621 tatagataaa ggaaggaaga catggcctta gaagtaatta tgccaaaagc cggcgtggat
     7681 atgacagaag gacaaatcgt ccaatggaat aaaaaagtcg gagaatttgt aaaagaagga
     7741 gaaatccttt tggaaatcat gactgataaa gtcagcatgg aattggaagc cgaagaagat
     7801 gggtacttga ttgccattct caaaggagat ggtgaaactg tccctgtaac ggaagttatc
     7861 ggttaccttg gtgaagaaag ggaaaacatc ccaacagctg gagcagcatc gccagaagct
     7921 agccctgtac ctgtagcaag tacctcaaac gatgatggta agagcgatga tgcttttgat
     7981 atcgttgtga ttggtggagg tcctgctggt tatgttgcag ccattaaagc tgcccaattc
     8041 ggcggtaagg ttgcccttgt tgagaaatct gaacttggtg gaacctgctt aaaccgtgga
     8101 tgtattccaa ccaagaccta ccttcataac gctgaaatta ttgaaaatat cggtcatgct
     8161 gcaaatcgtg gtatcgtgat tgaaaatcct aacttcactg ttgatatgga aaaactttta
     8221 gaaactaaat ctaaagttgt taatactctt gttggtggtg ttgcaggact tcttcgtagc
     8281 tacggagtta ctgttcataa aggaattggt acaatcacta aagacaagaa cgtcttggta
     8341 aatggttctg aattgcttga aaccaagaaa atcattcttg ctggtggttc aaaagtcagc
     8401 aagatcaacg tccctggtat ggaatctcca cttgtcatga ctagtgatga cattcttgaa
     8461 atgaacgaag tgccagaaag ccttgttatc atcggtggtg gagttgtcgg tatcgaactc
     8521 ggtcaggcct tcatgacatt tggttcaaaa gtgactgtta tcgaaatgat ggaccgtata
     8581 gttccagcta tggatgtgga agtttctaag aaccttcgct tgattcttga gcgtaaagga
     8641 atgaccatct tgactggtac taaactgcaa gaaatcattg aggaaaatgg tcaacttcgt
     8701 atcaaggttg aaggaaaaga cgatatcatc gcaagcaaag ctcttctttc aattggtcgt
     8761 atgccagacc ttgaaggtat tggagaggtt gagtttgaat tggatcgtgg ttgtatcaag
     8821 gtcaacgaat acatggaaac ttcagttcca ggcatttatg caccaggtga catcaacggt
     8881 actaagatgt tggctcacgc agctttccgc atgggtgaag tttccgctga aaatgcactt
     8941 aaaggaaatc atgcagttgc caaattgaat ttgactcctg cagccatcta cactctccct
     9001 gaagtagcag cagtaggttt gacagaagaa caagcccgtg agaaatacga tgttgccatc
     9061 ggtaagttta actttgctgc taacggtcgt gctattgcat ctgacgcagc tcaaggtttc
     9121 gtaaaagtta tcgctgataa gaaatacgga gaaatccttg gtgtacacat tattggtcct
     9181 gcagccgcag aattaataaa cgaagcatca agcatcatcg aaatggaaat cactgttgag
     9241 gaaatgctga agaccatcca cgggcaccca acttactctg aagtgatgta cgaagcgttt
     9301 gcagatgttc taggaatggc catccattca cctaagaaaa aataaaacga agatagatta
     9361 gactggaagg ttatttccag tttctatcat ataaagtaaa gggatatcat gaaatacatt
     9421 atcaatcatt caaatgacac tgcttttaat attgccttgg aagaatacgc ctttaaacac
     9481 cttttggatg aggatcaaat cttcctactt tggattaaca agccatctat cattgttggt
     9541 cgtcaccaga acactatcga agaaatcaac cgtgattatg ttcgcgaaaa tggtattgag
     9601 gtagttcgcc gtattagtgg tggtggagct gtttaccacg atttaaataa cctcaactac
     9661 acgatcatct ccaaagaaga tgaaaataag gcatttgact tcaagagctt ctcaactccg
     9721 gttatcaata ccctggctca acttggggtt aaagctgagt tcacaggtcg taatgacctt
     9781 gagattgatg gtaagaagtt ctgtggcaat gcccaagcct atatcaacgg ccgtatcatg
     9841 caccacggtt gcttgctctt tgacgttgat ttgtcagtcc tcgcaaatgc ccttaaggtt
     9901 tcaaaagata aatttgaatc aaaaggtgtg aaatccgtcc gtgcccgtgt aaccaatatt
     9961 atcaatgaat taccaaaaaa aatcacagtc gaaaaattcc gtgatttact cttggaatac
    10021 atgaaaaaag agtacccaga gatgactgaa tacgtctttt cagaagaaga attggccaaa
    10081 atcaatcaca tcaaggatac taagtttgga acttgggact ggaactatgg taaatcacct
    10141 gaatttaacg tccgtcgtgg aaccaaattc actagtggta aggttgaagt ctttgctaac
    10201 gttactgaat caaaaatcca agacatcaag atttatggtg acttctttgg tattgaagac
    10261 gttgctgcag tagaagatgt ccttcgtggg gtgaaatacg aacgcgaaga tgttcttaag
    10321 gcgctaaaaa ccattgatat cacacgctac ttcgctggta ttagccgtga agaaatcgct
    10381 gaagcggtag ttggataaat caaaaagaag ttggccaact aaccaacttc tttttttgat
    10441 atttatttac ataatttaaa atacgtaaaa ttataaacta tctagagcat tcttttgttc
    10501 atcattaaca atatgggtat agaggtcagt gacttgtgtg ctggcatgtc ctagttggtg
    10561 actgactaaa acttgtgatt tagtcgcatc atagagccta gttgctagcg tatggcgcag
    10621 tttatggggt gttacacgca ctttaaaatc ctctgagtat ttagcaacca ttttctcaac
    10681 gctagaagca tcgatacgat taggaacacc tctgtagaga gttaaaaaaa gggctgtatc
    10741 tgttttttcc gttttatagc gttgattccg aatggccaga taattctcta aataaggttt
    10801 agcaaaagca gcgacattga ctgagtcacg tttgccacct tttcgagtaa catcaataac
    10861 catcattttt agattgagat ctcttagatc tagattaaca gcttcagata agcgaacacc
    10921 agatgccaag agaagggcaa taatggctaa atctcgttct ttatttttgt tgaatgatga
    10981 gagagctcga tttgaaagct gttgtgggtg ctcttgatcg atataagtta gaaaaccttc
    11041 tgtttcatca cctagaaaga gtttttgctt gatattttca gctctggcag caagggtttc
    11101 tttctttttc ttggttgaaa cttttttcat tacattacga tagaaataag gttccccctg
    11161 atcgttttca acctcctcgg ttagatactt gtaaagacta gaaagtgctg ataaggttcg
    11221 attgatagtt gtctgtgaaa caccctgttt tgttgtatta gcattcagca agggacgttc
    11281 acgtagataa aggataaagg attccatgtc tttcttagac atattttcca aaactgataa
    11341 aggaatatcg gatattttat cagcgtttga aataccagac tccaaaaccc agctgaaaaa
    11401 tcggtcatat tccttaaggt attcgtacag ggttgtaaaa ctgtagggta cagccagctt
    11461 agattggtag tattccagaa cataccaggg catgagttgt tttagtttgt cgattcgttc
    11521 cagtaaaatc tcacgtttca tgtattttct ccataagtaa gtatactagt agtatagcat
    11581 agacttgtat atttttcaag aaaattatag tttttcagaa agatgttata ggagtttttc
    11641 aaagtgataa aaagacttag acctacaaac aaaacagaat aaggaaaata ataaaaatct
    11701 cacccactaa acttctgtta atactacata gctagaaatt gatttgattg tcctgattgt
    11761 tttatcctat ttctatttca tttcactata taattgctat tgttttcttt ttcatgattt
    11821 taatcttact gtacagattt gatacagtaa actcctttct agctttatgc tttatcattt
    11881 ctaacttaat tatagtctta tttttaataa agttcaatta tttatatgta aaattcctca
    11941 tcagtaaaaa ataaccgatc tcatttctga gaatcggttt tctaaataaa tcaagctgat
    12001 catttacata acataaatta tgtaaatgat tgtactacaa caacaaatct ttgacttttc
    12061 caatttcact ttttggaata accaggtgaa tcatatcacc cagatacatt ctggttgagc
    12121 cgttaactgt ttggctcttg ccattatgga cttgagttgt gatgaggacg ttgtgtggta
    12181 agttgagttc atgaacttgt ttcccagcaa ttttatcaga aactggtatt tcgataagtg
    12241 taacttctcc ttcgctagat acttcttctg gaagcatttt ttccagcatg gcttcataga
    12301 ctggcgtacc tttgagcaaa tccatgataa tataagaaac aagagtgaca agaccaagtg
    12361 gcatgaggtt gcgaatatct cctaccatct cagttacgag gatcatagcg gttaagggag
    12421 cttttgatat ggctccaaaa tagccactca ttcctagaat gacaaatata gggaattgct
    12481 cttgactgac aagtccaaga ttgacacaga tagcaccaat taaggcacca agcaaagaac
    12541 caagagctaa aatggggagg aaaattcctc ctggcagtcc acttccatag ctaatcatac
    12601 tccaaataaa gcggatcaaa aagtaagcta ataaaacttg gaaactaaaa ttttgttcag
    12661 ttaaagaaag gacaagctga tttccgccac caatgatttg aggtaagaag attccgactg
    12721 gtatgataag gataaaagcc aagatgggat aataagctct atccaaatgg attttttgac
    12781 caatcaagtc ataaactctt ccaacgttta atacagcttt ctcatagaga aagcctgaaa
    12841 atccaaggaa aattcccatg acgagatata tccaatactg atctagggtc atgggaggaa
    12901 tgttatctgg catatccaat actggtgtca aaccgaacat gagtagagac acaaagtttg
    12961 ctacgatgct ggctgctaga gttgagaccc agaaaaagcg cgaaaaatgg tgatagactt
    13021 cttctacaac aaagagaagt gctgcaatag gagcattaaa ggctgcggct aaacctgctg
    13081 cagctccact ggcaatcaag gaacgttcct ctactggact ggatttgagc cacttggcaa
    13141 ttcctttacc accaactgct ccaagttgaa tactgggtcc ctctcgaccc agcatgagtc
    13201 cactggcaat agcaagaata cctagcacat attttttcca aagaatgccc caccagttga
    13261 gggacatgag gcctttcagt tcggcttcga cttgaggaat tcctgagcct ttaatatctt
    13321 tttctgaccg tgttagtttg gcactgagcc aacagatgag tatataaaac aaaaccagta
    13381 caaaaagatt gcgtactaag tacccttgat cttgataaac tccttgtatc aggtggaagc
    13441 ccttttcaat taagaaacga aaggatccga cgataattcc aacgatgagg ccgacaatga
    13501 ttcctcgacc aacttgggat agtatagtgc tggatgcaaa ggcgaattct ttcttagaac
    13561 ggactatttc cgactgttcc tccatggtat ttcctttcaa ttaactttct tttttaccta
    13621 aaaccagtga tttaacgggt tcaaagctgg ttcggtgaat tggggtaact cctagttttg
    13681 tgaggccttc cagatgttta gctgtgccat atcctgcatt agtagcgaaa tcatagccag
    13741 ggaactgctg atcgtattcc ttcatcaatt catcacgtgt taccttggct actatagatg
    13801 ctgctgcgat agagagggag ttggcatctc ctttgataat ggaggtttgt gaaatgggca
    13861 agtccagttt catggcatca atcaaaaggt gctctggttg agggctgagc tgggagattg
    13921 cttcttgcat ggctagtttg gttgcttcat agatattgac ttggtcgatg acctgattat
    13981 ctatgatacc aattccaatc gacaaggctt ggtcttgaac ggcttggaaa atctccagat
    14041 gtttcttttt aggaattttc ttgctgtcgt tgagaccttt aatcttacaa tttttaggta
    14101 aaataacggc cgcagcgact acaggaccag caagaggacc acgaccaacc tcatcaatac
    14161 ctgcaattaa ggtcaatcct tgcttataaa gttctttttc ataagaaagc atggattcca
    14221 agcgcaaatt ttcatctaat tcagcttgaa tggctctttt acgcttgctg atttcctttt
    14281 gaactcctga gcgattatcc ttttcaagat ctaaaaaaat agggctttct aactccttga
    14341 ctgtcacaag gagttctttg atttctttaa tcgttgccat cgaggtcttc caatgtatct
    14401 aaggtatagt taccgagttt gccatcacgg acttccttca cgaagagact gtaaaaacgg
    14461 tcatagtcat cacggaaacc gagggcgcgg gtcatatcca taataatcac aggcgcttct
    14521 tcttcaattt tcatttgttt gaagcgttca gccagctttt ctggataatg ttctttgaaa
    14581 taattgatac caaaaatggt aacctcatcc ataggaagca actggtcttt gatagctcca
    14641 gtcaatgcca acttaagtgc aacagtttca tcctcaaact taggccagag aatccccggt
    14701 gtatccaaga tttccagatc tttattggtt ttaagccatt gttgaccttt tgtgacccct
    14761 ggcttgtttc caacaacagc aatcttttta ccagccaaac ggttcatcag agttgattta
    14821 ccagcgtttg gaatcccgat aatcatggta cgcaaggttt caatctgaat cccacgttct
    14881 ttctggcgag caatcttatc agccatgagc ttcttggccg catctgttac aacttttaca
    14941 gtcacttgct ctttggagtt gatagctagc gtctggattc cttgtgattc aaaatactga
    15001 cgccattcct tggtcattgc tggatcagcc aagtcggcct tgtttaaaat caagagtttt
    15061 ggtttatcac caacaatctt gatcaacata ggattttgac tagatagagg taagcgtgca
    15121 tcaactaaaa tcgtcacaaa atcaacaaat tttaaattct cctgcacttg tcgacgagct
    15181 ttagacatgt gaccaggaaa ccattgaata gtagccattg agtttttttc ctttcgtagc
    15241 aaggatttag atcccctatt ttattttact atagtttgaa catagagagt tttcaaatga
    15301 atgatgtcca aatagttctt gttttatgac atagaaatct actttatatt atatcatgcc
    15361 ttctttattt tgtccgatga tagcctttta ccctatcttt taccctatat agaaaaaagc
    15421 catcaaatga tgacttttca gagggagcaa aaaactgttc ccgtcatatt atgaaccaaa
    15481 agaactaaac taccaacagc taataggcct aaagctgtaa gcgcagaagt tgatgaacct
    15541 gttgcaggaa gagtttcctg ctgataaata agagcataac ttacttcatt atcaggagga
    15601 attcctgctt gaatcttggt ttgttcttca tcaccttttt aaactttatt tcctaatagt
    15661 aaacactatt ttttattctc aaaaattgaa cttctaaaat catttgtttg gtcaagatag
    15721 gctttaaaga ttgctctctt caacttatgg acggcactgt ccgtttctgg attataatta
    15781 ctccaacgtg tacctgtagc atcctgcaaa acagcttcat ccattagttt ctgcaattca
    15841 tccacattat tgatagtctt tgtgccatat cttggccatg gttttgtcgg atctttaaag
    15901 gtcacctgct tcaagtttcc aaactgatcc acccgttctt ggtacatagc tgtcttaaat
    15961 tctgcccaag ttttatactt accatcaaat acctttttca aaacaagctc atcggtcacc
    16021 aagccccgtt ctttaccata aagattgata gtttgccctt gttgtttagc atcttcttcg
    16081 tattggttgg aaatatatgg taccatacca tctttaaatc ctttagcagc tagaagttca
    16141 aaagctatcc ttcgtcccat aaggtcacct ggagttcctt tctcaccgct caatgctgaa
    16201 aagattggtg caaagagttt tatagtaaag tagccatttc tctcataagt gccagcctta
    16261 tactcacgag ctgaaagaat gttattgtca atcaaactat caaagctcgt caatttttta
    16321 gcttcatctt cagtcaaatt tttcacaaca ttagtagcat aaacatcatt tccatcagca
    16381 ggatctgtta gatattggtt ctcgattttt ctgagagctt ctattttctg gtaaacactt
    16441 agtttattaa cgattgactg cccttcgaga tattccatca tgtagataag gtcaaacatg
    16501 ttatggacat agttctgaag atctgctgcg ttttggaatc tctctgtcgg atccaagact
    16561 tgaagacggg atccctctgt actatctgat tttgagtgtt tcaagataga attgatggta
    16621 atggttgcgt cacttggttg gtcaggggct tgcaataagc cttttgcgaa gaactctggt
    16681 cccaagccac ttcttcgacc atagccacca aggtaaatat cctgatccga atcatgggtc
    16741 atttcatggg tataagtaat ggctccatcc ttgtccagca tgcggtaaga catatagtag
    16801 acgccgtccc ctgtagcgta ggctccatgc tggttgtgta ctaccttatt gccaactggt
    16861 ccaaagaagt tcttcatagc tggattggag ctatcaaact tagcctccgc tgtagctttt
    16921 cctgatgttg tatcatcccc aaacttatag gcatcataaa ggagaatcgt acgatagagt
    16981 ttttcgcgtg actgttcatc taaaatacga taccaataat cgtagtgatc tcgctgacgt
    17041 ttggctgttt cacgcgcatt ttcttcaaca aaatcattga gagccttgcc cgctttatgg
    17101 tcactactgc ggtagcgatc ataagctcca aatcctagac tagacatggt cgagatgaca
    17161 aatacggatc tctctggcaa ggtcaggaga ggcaagacca tattgcggta tttccaagta
    17221 ttactagtaa ttcggtcata aacaccgata gagtacttag ttcctgcttg cttttgcttg
    17281 gctttgacct ctgcaatagt ggatttttct tcgacaatgt aagccttagt ctctgattta
    17341 aaccagtcat tattgcttgt atttggtaaa aagacttttc ggtaatgttc cagcgtgcta
    17401 aacaaatctg tcgttccatg ttgactggca agactgatac cataagtatc gacattattc
    17461 ttagctagaa gattgttaaa gccagattta cccaactcaa tcagagtatc taatggtgaa
    17521 gcattcccct taccaaagaa gtccaaatgg tacagaacta ggtctttgac attcacctga
    17581 ccatagctaa agttatacca ccgttccaga taggtcaagc caagtagcaa ggcttccttg
    17641 ttgcgtttga ttttatctac aagataacct tcagtgactg ggttagcact agccagtcca
    17701 gcatccgctg acaagagttt tttcaaactg tcttccagtt gttgttttgt tttggcgaac
    17761 tggtcttcta gatagagctc agtttgcttg acgtttggag aaatacccag cgtctttctg
    17821 atggcttctg aatgatagtc aaccttttgt aagtcaggta agacttgctt gatgatagag
    17881 gtttggtcat acaggaattg gtttggcgta tagagaagtc cagtattgcc cagactatat
    17941 tctgctaatt tggcgaaatc attctggtat ttgagatcca gcttctcaga taaatcatcc
    18001 ttgtagtgaa gcaagagttt gtttgcagtc tgtttgttag aaacaatgtc tgtgatgact
    18061 tggttgtcct tcatcatgac tgctgacaag agttcttttt gatataaaag actgttctca
    18121 ttgaccaggt ttccgtattt gacgatggtt gccttgttgt agaaaggtag caatttttca
    18181 atgtttttat aagtcaagtt gcgcttagct tgataatagg ccaccttaga aaaatcactg
    18241 tcttttttgc cacttgttga aagtggctcc actgttggta gaatgaaagg attgatttct
    18301 gcttttttgc ttgcaatttg agaagcatct agcattgttc ctctttcttc aaaggattcc
    18361 ttgctgacga cctcatcctt gaccaaggtg acattgtaga ctctgttggc cttgctgctg
    18421 aatgtgtcct ttaccttcat ttcgttatag tggtaaccag tgatggcatt tccgttggtt
    18481 acattaacat cgctgagaac attggtcaaa cttccagcat acctaacatc accagaagtt
    18541 cgatcccaca aattgcctgc cactccagcg actctaccaa agtgcttgac attgttgata
    18601 tcaccttcag catagctatc ttggatctgt gcatctcggt ctactaggcc tgcaagtcca
    18661 cccacagtct gatctgaagt atttgtgtta gatgaaatgg ctactgtcgc ttttgactta
    18721 gtaagtaaag ccttgtcacc tgtcaaatga ccgaccatac caccgatatt gtaggcagca
    18781 gtcgtttcat aagtgttgat aattcttccc ttgaaactgc tctctgtgat gcttgattgc
    18841 tcagccttag ccagcaaacc accgatacca cgttcaccag ccagaacacc atcgacgtga
    18901 acttgcttaa tttttgtatt attctgagct tcatttgcca gtgaaccgat atcatctttc
    18961 cctgaaatag caacattttt tagactcagt ttttctactg tagcaccact caagttttca
    19021 aacagaggtt ttttcaaatt atagatagca taattcttgc catctttttc accgattaaa
    19081 cgaccagtaa aggtgtcctt gatataggat ctttcatcag gaccaagctc cacttcgtta
    19141 gcattcaggc tggccgctaa atgataggtt ccagagggat tttggtttat agctttgacc
    19201 aggttgctaa aggaagtaaa gtttgtattt tcctctttag ccttcttatc gaggtagaag
    19261 gtgaaattgt cgacatattt attttctagt tcttgctgga gtttctcagc tttggctgtg
    19321 attttataaa ctgactgccc atttcttttc tcttcagtta ttgaagctac tggtatatag
    19381 acatctttaa atgctgaaga ttttaccttg acaaagtaag tatccgtatt ctctggaatt
    19441 ccatccaatg aaacatgttg tctgtaggtt ccattcgtct gactatacaa ctcaatatca
    19501 gaaacatttc ttaattcgag ttttttctct ggttcttcta cctttttatc agggtctagt
    19561 tcattttctt gtttaatttc ttcgtttcca tttgaattgg atgtgtttga ttcggttgaa
    19621 acatcctcag ttgaatttcc gtttgatggt tctggttctg tttgtccatt ctctgatgtt
    19681 gtattacctg aattttctgg ttttgttgca gttccgtttt tttctggttg atttgattct
    19741 tcaactggtg gttttgaatc actaggttta ttggatactt ctccagtatt ttcgttagct
    19801 attttcccag agtttgtttg tgtttcttct gcaggttgaa ctggtttttc tgtttcttga
    19861 tttgaggtac cttctactgt gccttcattt ggatttactg gaacttcttc tacagttttt
    19921 tctgaatttt catttttaga gtcattatgt tctggtttat ttgattctcc aactgaggtt
    19981 gtcgaatcac taggattact ggacacttcc ccagtatttt cgctagatgt atctggtgat
    20041 actttctctg aattcgttgt tgattcttct gcaggttgaa ctggattttc tgcttcttga
    20101 attgaggttc cttctgtagt accttcattt ggatttactg gtgtttcttc tgttggtttt
    20161 actggaactt cttcagtttt ttctggacct tgttctttgg tcttctcaac cggagtttca
    20221 ggttttactt gctcaatatt acccttatat tctggcaatg gggctacctg ctctggttca
    20281 cctttatcac ttaccacagt atctggcgac tctggttgaa cctcagtctc acctttgtcg
    20341 gtcacaactg cttcgggtaa tgtcggttga acttctggtt cgcctttatc acttactaca
    20401 gcttcgggca actcaggctg aattgcgggt tcaacaatag ctccagactg tacgtcctta
    20461 tgttctacac cagtctcagg ttgttccttt ataacttgag tttttttagt acctttttcg
    20521 actattcttg gactaggcgc agtcgttgaa gttgaaacaa tttctcgcga aacttcttcc
    20581 ttgtttacag agaatattct gacgatttca actttcttac ctaatttacc ttcttgtttt
    20641 actcttacag ttccttcagc taaatcagga ttttcttgaa tttcttcttg aaaatctatt
    20701 tttgtctcta tagtttcctc acgatataag agttcaggtt tgttcaattg acctgataaa
    20761 acttcatcct gtggatttaa tgtatttacc ccagtctttt cctttggaga aatcttctcc
    20821 tctttcttcg tttctagatt cttatgttcg gctaattgtt cttgagaatc tgaagattgt
    20881 ttctcttctt ttcttggatt gattaattta gtagagaaag gtttttcaac tacttgaact
    20941 tctgtcggct tagttgaaga aacaggtgtt tgttcctgaa tagcttgtac tgttgatgga
    21001 tggtctacaa aatttggtgt aacattataa tccacctttt gttgttttgt aggagtggct
    21061 gctgattttt cttgattact tacttcaaaa tcagaagtcg tttttccctc tttgatatat
    21121 ccaatataag tgtaacctga aatctcttta ggaagaggta atttttctcc agaggtcaat
    21181 tcatagtccg tattgtaatt tagcaaaaga tgattttcta aagcatggac tgaaactaag
    21241 acaccatttc ccattcccgc aaccaatact aaatgtaata ccgttttatt cttaaccttt
    21301 ttcttggaaa cagcaaaaat taaaattccc agagcagcta agctagcacc agcaactagg
    21361 gcttgcctct cattcttgct tccagtattt ggtaattcca ccagttgatt ttgagaattt
    21421 aacttataaa caagataata agtttcatca tcattctcca cgtatgtcgg aatatcatag
    21481 acaagctgct tcttttcttc tgatgatagc tctgaatctg ccacatattt atagtgaact
    21541 cccgcagttt cttgagcatc cacagatgaa ctagctaata cagacataaa aaataaactt
    21601 gaaatcgttg cagatacaag tcctactgat aattttctaa atgaaaaacg ctcttgtttt
    21661 tcaccaaaat acttttccat tattcctcct tgaaataaaa tttatatatg ttacaaagac
    21721 ctttattata ttagtgtatt atctattatc tatagaaaag gcagtatacc ttaattatac
    21781 tcttaattta caaaaaagtc ttaaaattga gatgcgcttt catactttgt tttatattat
    21841 ttgggggtac aataacacct accatgaaat ttacacggta ggtgttactc atatcactaa
    21901 tcgttctaaa aatggtttga ggcagttgag gagaattcct tctatccagc ttccttgtgc
    21961 tgatgagcga tggtcttcct gcaggctttt ttttagaaaa tctcggactt gttctggtgc
    22021 gatttcaaat tcaaaggctt tcattttata gaaaaagtcg atgagatgat cggacaggta
    22081 ttcagttgaa aagggtactt caccactttt tcgatattct aataagagcc tagaaaatcg
    22141 agctttttct tcaggaagct cacgaaaata ggaattgagg agccaagtct gcttctgttt
    22201 tctttcaatt ggatcctgac tggcaattcg ttggtctttt tccagctctt tttggtattg
    22261 tttggccttg atagcccgtt ctgctctatt tttaccaaaa agaatttttt cccacttgcg
    22321 ttcttcttga gtcagggtct ctgtaaagcc aaagtaatct tgataagcac gctctgcggg
    22381 tcccatggct agaaccagat tgtctgcata ttgcttggcg attttatccc tcttcttgcg
    22441 ttctttctct gcctggatac ggagttcttg ttcgtagtca attttctcct tgcctagctt
    22501 gacaaggtag agttggtcat ccgatttccc aagtaaaaag ggtttgatac acttttcaag
    22561 gacttcttcc atccgagcct ttttctttgg ttccgccttg gtccaacttc ctccctgaaa
    22621 gacttctagg aaaagctggt agtctctctc aggcgcaaat tgattgccac gattgggttt
    22681 gaaaacacct ttttcccaga gccattttag aagtcgctcg tcaaagtcac ttttattgac
    22741 cttgattttt tcctttttct gagcttttct ggttagattt tcaacctttc tgagcagttt
    22801 ttcttcctct tccaattgct ggtcaaggga caatcgatga aaatgacgaa cacagtcgct
    22861 accaattgga aagaggcgtt ggcctgtgac accgttaaag agttcataag cgtatttgat
    22921 ggcatttcca cagacacaat tgctacggcc gataccgtta aaaatcaagg aaacttcatt
    22981 ccattccttg gtagcttgtt cccaagtatc cgctttcgaa gcctgtaaaa ctgcatcgtg
    23041 cagggatttt ctaactggaa gtgtcatgag gtctcctttc taatactcaa taaaaatcaa
    23101 agagcaaact agaaagctag ccgcaatcag ctcaaaacac tgttttgagg ttgtagatag
    23161 aactgacgaa gtcagctcaa aacactgttt tgaggttgtg gatagaactg acgaagtcag
    23221 taaccatata tacagcaagg cgaagctgac gtggtttgaa gagattttca aagagtataa
    23281 gttatacttt tacaacttga acctcgtctt taccgagtaa aatcaagtat ttttcaatat
    23341 tttcaatcga ataggctcgt gataaagcct cttcgtatag agctaactga ccacgatagc
    23401 ggtctacgag ttgacttggt tcatcatagc ggtctgtctt gtagtcgaac agaacaattt
    23461 tgttttcgta aagcagatag ccatcaagga taccacggac aacaaagtct tcctgactct
    23521 tttggtctcg tttgagcatg gagaaaggtt gctcgcgata gagatggtcg gtattagcaa
    23581 gaatttcctg accgagtact gtgtcaaaga aagcaagaat tttatcaaga ttgatcttgt
    23641 ctctgacagc ttggctagtt tgaacttgtt tgagtgtttc tgttaggcta gcaagggtta
    23701 gttgctggct gaggtcaatt ctctgcatga gttcgtgagt agcactacca atctcagctc
    23761 cagttacctt ttctttggtt gaaaaatctg gcaaatcgaa gctgattttc ttgcctactg
    23821 actgaccttg accagcaatc tcgacacctt ccatatccat aactggttcg tagaatttct
    23881 tgatttgact tggggtttga acactaggaa gttcaatagc tgcgcggtga agagtattat
    23941 aaacttccac ctccttcagc atttccagag cttctttgat ggtatctgac tgacgattgt
    24001 ctgcttggga gctatcttgg agaggactct tggtttccaa ctctccgata gcttctctgg
    24061 tcaactgatc ttcgccaata aaacgataac taaagttgag cttgtcctta gtaaacactt
    24121 tactgatagc ccaaagccaa tcttggaaat tccgtgcttg cagtctagta ttgctattta
    24181 gtttcccatt tttggctgct gggtattgct tgacttccag cttttcacga gaacccttgc
    24241 cgacaagata gagctttttc tcagcccgcg tcatagcaac atacagcaaa cgcatctgct
    24301 cagaatagct tgctagctgt aattcctctt cgttctgcct ataggtcaga ctaggaatgg
    24361 agagtttgat ggttttagga tagtggtctt ctactgcccc tgtctccatc ttggcaatat
    24421 atttgacacc aagaccattc tgacgactga gaatgacttc tgacatagag tcttgcttgt
    24481 tgaaatcttg atccatattg aggataaaga cgtaaggaaa ctccagccct ttactcttgt
    24541 ggatggtcat gagctctact gcatcttttg gcggtgcgac ggccacgctt gccaaatcgt
    24601 gctgggcttc taagacttgg tcaatcatac gaataaaacg cgacaaacct ttgaaattgc
    24661 tcttttcaaa ttgatcagca cgcagtgcta gggcatagag attggcctgc ctagcaggac
    24721 cattcggcaa agccccaaca tagtcataat aaaaacggtc gttgtaaatc ttccaaatca
    24781 agtcatagag agagtgggtt ttggcataca agcgccaaga agctaggata tccatgaatt
    24841 gctttagttt ttcagctaga gctgtgtgaa tcaagccttt ttgactactt gccatttttt
    24901 gtgcattgac cagtttctca tagagatttt cgtggacttt atcctctgct ttctgaaggg
    24961 acaaacgtgc tagctcatcc tcatcaaaac caaacattgg agacttcata agggcaacca
    25021 aggcatagtc ttgcagggga ttgtgaatga cacgaagagt gtctagcatg acttgcactt
    25081 ctagggattg gagataattg ttttgctctc cgtcagtttt gacaggaatc ccgtactcag
    25141 acagggcgag gagaatctgg tcattacgac tgcggctgga ggtcagaagg gcaatttcct
    25201 taaaggtaac acctttttct tgatgaagtt tcagaatctc cttgataact aagcgcattt
    25261 cgcctgttag tttcgtttct gtttgactct cttcttcctc acctgtatcg tccttgtcgt
    25321 agaggagaaa ttctgccttg ttgtctggat tgggagtcag tttggtattg gcaaaaacaa
    25381 gctggtgctt gttatcatag ttgatttcgc cgacctcttg gtccatgaga cgttcaaaga
    25441 catcattggt tgctgacagc acttctgaac tactacggaa attttccttg aggagaatga
    25501 gcttgccttc ttggggattt tgcgcatagc gttggaattt ctcattgaaa atctgcgggt
    25561 ctgcctgacg gaaacgatag atggattgct tgatatctcc caccataaag cgattgtggc
    25621 cattagacaa caattccagc atccgttctt gaatatggtt ggtatcctga tactcatcga
    25681 ccatgacttc atggaagcgc tcctgataag actcacgaac ttgtgggaaa ttttctaaaa
    25741 tctcaatggt gtaatggctg atatcagcga attcaaaggc attttcctgt cgttttctct
    25801 gacgataagc ctctacaaaa tcgctcatga aagattggaa ggttttagct agtttccaag
    25861 tgtctccatg ataacgttct tgatagtcga gaatcgctat ctggtctgat aattgtccta
    25921 gtttagtaaa ctgggtcttt ctctcttcgt tgtaggcatc agccaggggc ttcaaatcag
    25981 ccttacggct ggcattagtc agagcacgac cgtttttctc cttagagatg gcgacaacac
    26041 gcgcaagtac tgcctgataa gcctgactat cgaactcctg atttagggag ccaatttcat
    26101 ccagaattaa ctgaacattt tctaaatagg cagcctttgc aaactccttg gcatcgttat
    26161 ccagatggta acggaaaaag ctttccaaat cccagagggc ttgtttgatt tgctcagtca
    26221 gtttttcttt ttcactggta aaatcagctt tctcaaagcc tttgaggaaa gattcactca
    26281 gccacttttg aggattactg gtggattgga ggaagtcata gattttatag acttgctgcc
    26341 gcagaccccg ttcgtccttg ccacgcccag caaagttttt cagcaaatga ctaaagctct
    26401 ctttctgttt accttggtaa tgcgcttcaa agacctcatg aaagacttcg ttttcgagaa
    26461 gaagttgctc gctttggttt tgtaaaatac ggaaattagg tgcaatatca agcagataac
    26521 catgtttgcc aaggaatttt tgtgtgaaag agtccatggt tccgatggca gcgttgggta
    26581 ggtctgccaa ctggcgaccc aagtgttgtt tgagatcgac atcatctgtt tcttggattt
    26641 tcttgctgat ttttttctct aaacgttctt taagttcagt tgcagccttg acggtaaagg
    26701 ttgagataaa gagttgagaa atttcgacac cacgcgccaa ttggtccaga atgcgctcta
    26761 ccatgacaaa ggtctttcca gaaccagccg atgctgagac caggatattc tgaccagaag
    26821 tgtagatagc ttcgatttgt tcggcagttt tcttctgttc cttgctcgaa tttgcttctg
    26881 cttcttgcag tttttgaatc tcctcctcac ttaaaaaggg aataagcttc atcgatttaa
    26941 ctcctctctt attttttcaa accaagcttg cttgagtttt tctccgacca gacgcttgcc
    27001 atcagctagg tccaattttt ctaggaaacg ggcttggccc agatggtaat tggcttcaaa
    27061 gcctgtaata gcctgatgtt gctggacgta tggggcaatg cttctgccat tttcagtata
    27121 aggattgatg gcgaaccggc ctgctaaaat cttctcagca gctttcttgt aaagataggc
    27181 attgtagtcc agtaggagct gaaattcctc atctgtcagt tgattagcct tgtttttgtt
    27241 ataaaattcg cctaaataac tgctttcttt ttccaagaag agcccttggt atttcataga
    27301 tttgctggct tctaccactg ctcctgccag actttttacc gccatcagag attggacagg
    27361 ttcagccatt tccaagtaca tggcaccgaa aaagttctgc tccccttctc tttttagggc
    27421 agcaagatag gttggtaact gagaattgag cccattaaag aaatgaggaa actggaactg
    27481 agtcagactg gatttgtagt ctactactcc tatcgctcca ttagctttca aacggtcaat
    27541 ccggtccacc ttgcctcgta caaagacact gcgtccattg tctaattgaa taaaggcttg
    27601 gtcttttcca ccaaaatttg cttcttcttt gatggtttcg atggctggat tgtgtcggag
    27661 aatatgtcca gtcgtccgtg caacatcaag caaaacttcc ttggtaaact gggcttccaa
    27721 actttcttga taaatagctt caaattcgcg ttcttgactg gtttcttgaa tagcttgttc
    27781 tagacgttgg tcaaaggaat cttcattagg caactgtaag gcgcgttcaa agatacgatg
    27841 caagaaattc ccgtgactac gggcatcagg acgcaaacgt aattcctcct gcaagcctaa
    27901 aacgtagcgt aggaaataac tgtattcatt gcgataaaac tctgtcaaac ccgacgtaga
    27961 caggtaaaac tcctgtttgg caggatagag agcttgcaag gtgtccttgg ctaaggtctt
    28021 gctgcttgga ctggttggga tagctggatt ttccagacct tgcagatcta gttttttacc
    28081 tatgacacgc gacagaacct tgacaaaagt caaatctcgc tcaatatcgc tcatctcacc
    28141 ctgctggtga taggcaacca gactagacaa aagactgtga taggacccca tatcctcctt
    28201 agacagtcct ttgtgattca tcctcttctc tctccgccta aatccaaaat ggatcaactc
    28261 ttgaagatag gcagattcct tactttcact ttcgttaaaa aggcttggag ccgacaagaa
    28321 caactgctta cgagcagaat tgaccaagga aagcatagtg tagcgatttt tcttgagatt
    28381 ttcactgctg gcaatcagta attgaacgcc ttcttcggtc gtttggttta ggttttgcct
    28441 ttcttcatct gtcagaagac tggtgttttg agaaattttt ggtaaattgt cctgagttag
    28501 tccaatagca tagacaaagt cagcagtcaa tggtgcaatc aaatcgtaac tctgcaccag
    28561 aacagtgtcc actgttgctg gaatggtacg gtattgggac aaactcattc cagaatggag
    28621 caaggctagg aagtcttcca gactaacctg tgaaccagca aaaacagtcg caaattgttc
    28681 taaaacatgg cagaaagcct tccaaacttc ggcttgtctt tcctgttcta cagcttccaa
    28741 agtggttgtc aaatcttgta actgcttggt cacagctcct tcttttagaa agacactcca
    28801 tttttgtagg aggttttcag ccttttgttt tcggctggca aagagggttt caagaggtgc
    28861 taaaattctc aggcggagga cattcaaacg ctcaagatta aattttccat ggtgggattt
    28921 ggtgaaggtt tgctgaaagg ctggcaagcc attgatacca agatagcgga tatattgctc
    28981 aaaagaatca atatcagact gactgaggtc agtatacaaa tcagttctaa gaagattaat
    29041 caaatcctcc tgacgaaaac ggtaacgttt taaagctaaa atagactcga caaactgagt
    29101 caagggatga tgagccatgg cttcgcttct accaagataa aaaggaatct gatactggtc
    29161 aaaaatggtt ttgagagata actggtaaga agctacatcc cccaagagaa tacgaaaatg
    29221 cttgtagctc aggtctgagt tctcatgtaa tttctgacga atgctacggg ctactagctc
    29281 caactcctcc ttttgcgtca aacaagacca gatttgtaaa ttttcacggt ctttctcatc
    29341 gatatccaaa gcgagttctg aaaagtcata agaagactcc aacaaacgag aggccttgtc
    29401 aaaactatcc atcttctcat gagtttgaga acagtcctga gcaggcgttt ggtatttaga
    29461 agccagatga tggagaaatt ttacgctggc ttggtagaga ttgccctcgc taaaaggact
    29521 ggtataggct ttcttactag cataagcccc gataacaatc tcaacacctt tgccgtgaag
    29581 taagtccaca acccgctctt cctcagcaga aaaacgagta aagccgtcaa tgaccaaggt
    29641 gatttgatta aaatcactac ttaccttgtc attctcaata gcctcaatca aatgggacaa
    29701 ctgacttccc tgggctaact gcccttgatt aagataggct gttactttct caaaaatcaa
    29761 gagtaaatcc gtcctcttat cctcatctgt taaattctcc aagtccaaaa aactcatctg
    29821 agatttggtc atctcatggt aaagctcaat taactgctgg atcaattgag gatcctgctt
    29881 aatagcgcca taaaaacgca agtccttggg atcgagttcg gcaaggcatt tgtaaaaggc
    29941 caacccaaga ccgatatcat caagagtagt tttaactggt aaatcattca agaccagata
    30001 acgagccatt tgagcaaagc gcgtgacggt aatcgaaaaa gaagcctgct gggacaagca
    30061 ttccagcacg gcgcgttcct tttcaaaaga aagagagttg ggggcaatgt agaagacccg
    30121 cttgccagct gcaactagct cttctgcctc tcttgttaga atttctgtca aagaagttcg
    30181 aatatcagta taaagtaatt tcatctcagc ctcgttggaa tttttcatca ccctatatta
    30241 taccatgatt agcctcgtaa atctgttaaa atatttaggc catcctttct tttcttcatc
    30301 atctgctaaa tcttaaatac ttagctttac ttgtattaga tagaataagt ctggctactg
    30361 aaaatcacat aataaaaaag cctcggtaac aagactttga gttttatgat tgtttcttag
    30421 gtacggaata cacttcaatg tgttgtccca gtatcttaat gtcgacgggt agattgtctg
    30481 atttatcgcc atcaacatcg gactctaatt cgatatcaga agaagtttta atattacgtg
    30541 cctttatata ttcaatattc ttgatagaat gattgaacta tagtaaattg aaactataat
    30601 agtacaccgt ggatgctaaa atattgctag aaattaattt gatttcccta atcaagctgt
    30661 tcgtatctta tttcaatcta
//
LOCUS       DAVHSY010000023        29783 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.023, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000023 DAVHSY010000000
VERSION     DAVHSY010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29783
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.023"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            520..1797
                     /gene="ltrA"
                     /locus_tag="VVR43_001256"
                     /pseudo
     CDS             520..1797
                     /gene="ltrA"
                     /locus_tag="VVR43_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            2257..3435
                     /locus_tag="VVR43_001257"
     CDS             2257..3435
                     /locus_tag="VVR43_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6149619.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTCINLVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            3749..3880
                     /locus_tag="VVR43_001258"
     CDS             3749..3880
                     /locus_tag="VVR43_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU6149620.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            3901..5451
                     /gene="dltA"
                     /locus_tag="VVR43_001259"
     CDS             3901..5451
                     /gene="dltA"
                     /locus_tag="VVR43_001259"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU6149621.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMKNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            5448..6692
                     /gene="dltB"
                     /locus_tag="VVR43_001260"
     CDS             5448..6692
                     /gene="dltB"
                     /locus_tag="VVR43_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU6149622.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            6706..6945
                     /gene="dltC"
                     /locus_tag="VVR43_001261"
     CDS             6706..6945
                     /gene="dltC"
                     /locus_tag="VVR43_001261"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU6149623.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            6938..8206
                     /gene="dltD"
                     /locus_tag="VVR43_001262"
     CDS             6938..8206
                     /gene="dltD"
                     /locus_tag="VVR43_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU6149624.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            8361..8801
                     /gene="adcR"
                     /locus_tag="VVR43_001263"
     CDS             8361..8801
                     /gene="adcR"
                     /locus_tag="VVR43_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU6149625.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            8801..9505
                     /locus_tag="VVR43_001264"
     CDS             8801..9505
                     /locus_tag="VVR43_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU6149626.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            9498..10304
                     /locus_tag="VVR43_001265"
     CDS             9498..10304
                     /locus_tag="VVR43_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU6149627.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            10314..11819
                     /gene="adcA"
                     /locus_tag="VVR43_001266"
     CDS             10314..11819
                     /gene="adcA"
                     /locus_tag="VVR43_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU6149628.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYTEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(12990..13763)
                     /locus_tag="VVR43_001267"
     CDS             complement(12990..13763)
                     /locus_tag="VVR43_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6149629.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            13939..15342
                     /locus_tag="VVR43_001268"
     CDS             13939..15342
                     /locus_tag="VVR43_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU6149630.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            15457..16095
                     /locus_tag="VVR43_001269"
     CDS             15457..16095
                     /locus_tag="VVR43_001269"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEU6149631.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            16107..16547
                     /locus_tag="VVR43_001270"
     CDS             16107..16547
                     /locus_tag="VVR43_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEU6149632.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            16540..16971
                     /locus_tag="VVR43_001271"
     CDS             16540..16971
                     /locus_tag="VVR43_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6149633.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            16962..17432
                     /locus_tag="VVR43_001272"
     CDS             16962..17432
                     /locus_tag="VVR43_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6149634.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            17457..18230
                     /locus_tag="VVR43_001273"
     CDS             17457..18230
                     /locus_tag="VVR43_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU6149635.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            18227..19027
                     /locus_tag="VVR43_001274"
     CDS             18227..19027
                     /locus_tag="VVR43_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6149636.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            19086..21380
                     /locus_tag="VVR43_001275"
     CDS             19086..21380
                     /locus_tag="VVR43_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU6149637.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFDPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTNYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            21390..24506
                     /locus_tag="VVR43_001276"
     CDS             21390..24506
                     /locus_tag="VVR43_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU6149638.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            24563..26329
                     /locus_tag="VVR43_001277"
     CDS             24563..26329
                     /locus_tag="VVR43_001277"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU6149639.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            26475..27626
                     /locus_tag="VVR43_001278"
     CDS             26475..27626
                     /locus_tag="VVR43_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU6149640.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGYDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            27771..28655
                     /locus_tag="VVR43_001279"
     CDS             27771..28655
                     /locus_tag="VVR43_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU6149641.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(28772..28849)
                     /locus_tag="VVR43_001280"
                     /pseudo
     CDS             complement(28772..28849)
                     /locus_tag="VVR43_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            29053..29304
                     /locus_tag="VVR43_001281"
     CDS             29053..29304
                     /locus_tag="VVR43_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU6149642.1"
                     /translation="MKEFQFERKQRFSLRKYVIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEY"
     gene            29292..29507
                     /locus_tag="VVR43_001282"
     CDS             29292..29507
                     /locus_tag="VVR43_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149643.1"
                     /translation="MGVLGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGK"
BASE COUNT         9418 a         4887 c         6343 g         9135 t
ORIGIN      
        1 atagcggata aggaggcttc aaactctaaa gtccaaaaag gtagtcgtaa cctatatgcg
       61 taaatcacga gagtaattga attcggacta aggtttgtgt gaaaagataa atctttctag
      121 agtctaaaga ctctgcgtca gatttcctat tttcactgta accttttaac gtcctcatat
      181 cttgtataaa cgaggaaaga tgtacgactt atcccgtgag gtctcatgag tgctgaaagc
      241 gtagtaacaa cgaatcatga gaagtcagcc gaacccatag tagtgaggaa acttccgtaa
      301 tggaagtgga gcgaaggggt gaatactcaa acagtctggg gagagactgt ttgaggtctg
      361 tcgctagaaa gagaaaacga cagattgaag taatcctact tcacttgtgt ctgtaaaacg
      421 agaggtctga tagaactgga gtctgtcacg tattgactag atgaaggctc accaatataa
      481 gatgtccctc aggcaccaaa acaagaaagg aatacgcaca tgtcaaaatt gctagataag
      541 atattatcac gcgaaaatat gctggaagcc tacaatcaag taaaatccaa taaaggctca
      601 gctgggattg atggaatgac tatcgaagag atggataatt atctcagaca aaactggcgc
      661 ttgactaagg aactgataaa acagagaaaa tataagcctc aaccagttct tagagttgag
      721 atacctaaac cagacggagg tatccgtcaa ctaggaattc caacagttat ggatagaatg
      781 attcaacagg ccattgtcta agtcatgagc cccatttgtg aaccccattt ctcagatacg
      841 agttatggtt tcagaccaaa taggtcatgt gaaaaagcca tcatgaagct cttagaatac
      901 ttaaatgacg gctatgagtg gatagtggat atagacctag agaaattttt cgatacagtt
      961 cctcaagata gattgatgtc cttagtacat aacattatcg aagacggaga tacggaatcc
     1021 ttgattcgta agtatcttca ttcaggtgtt atcattaatg gtcaacgtta taaaacacta
     1081 gttggtacac cacagggagg aaatttatct cctctcttat ccaatatcat gcttaatgaa
     1141 ttggacaagg aattagaaaa gaggggactt cgatttgtgc gctacgcaga tgattgtgtg
     1201 attacggtcg taagcgaggc agccgctaag cgtatgatgt attcagtcag tcgttttatt
     1261 gaaaaacggc taggtttgaa agtaaacatg accaagacta agattaccag accaagagag
     1321 ttgaaatatc taggttttgg gttctggaaa tcatcagatg gttggaaaag tcgtccacat
     1381 caagatagtg ttcggagatt taagcttaaa ttgaagaaac taacacagag gaaatggagt
     1441 atagacctaa caagacgtat tgagcaactg aatttgtcta ttcgaggatg gataaactat
     1501 ttctcattgg gaaatatgaa aagtatagtc gccagcatag atgagcgctt gcgtactcgc
     1561 ctacgagtga ttatctggaa gcaatggaag aagaaatcga gacgattatg gggattgctt
     1621 aagttaggag ttcctaaatg gatagcagat aaggtatctg gctggggcga ccattatcaa
     1681 ttagtagctc agaagtcggt acttaaacgt gctatatcaa aaccagtcct ggaaaaacgt
     1741 ggactggttt cgtgtttgga ttattacctt gaacgacatg cgttaaaagt tagttgaacc
     1801 gccgtatgcc gaacggcacg tacggtggtg tgagaggggc tagagattat cccctactcg
     1861 attaactccc ctgaaattta ttttaattat gcaaatttca cgtatttttg atgctgagac
     1921 gacgatcctg ggaacttttc agatattttt ttgactatct aaatctatca ttagaaaagc
     1981 ttagagcgcc aaaggatttg agcgtttttc tgatttttaa gactttttcc agtctctttt
     2041 tcgattgaag atgtaattat tctactaact aactaactaa cttcttagta ctagccaaca
     2101 acgataatca taattcctcc taaaattagg aataataaag gcaatagttt ttgttttttc
     2161 atgtaaaaaa cctcactttt gttttctgct attttatgct aaaatattaa aaatcaaatt
     2221 taattccaaa gtttgtaact aaagggggag cgctacatgt ctaattcatt tgtcaagttg
     2281 ttagtctctc aattatttgc aaatttagca gatattttct ttagagtaac aatcattgct
     2341 aacatataca ttatttcaaa atcagtaatt gccacatcac tagttcctat cttaatagga
     2401 atatcctctt ttgttgcgag tcttttagtt ccgttggtta ctaaaaggtt agcgctaaat
     2461 agggttttat ctttatctca atttggaaag actatattat tggcgatact ggtaggaatg
     2521 tttaccgtaa tgcaatccgt agcgcctttg gtgacctatc tatttgttgt tgcaatttcc
     2581 atactagatg gttttgcagc acccgtttcc tatgctattg tgccacgcta tgcgaccgat
     2641 ttgggtaagg ctaattcagc cttatcaatg actggtgaag ctgttcaatt gataggttgg
     2701 ggattaggtg gactcttgtt tgcaacaatt ggtctgttac ctaccacgtg tatcaattta
     2761 gtcttgtata tcatttctag ctttctgatg ttatttcttc ctaacgctga agtggaggtg
     2821 ttagagtcag aaactaatct tgaaattttg ctcaaaggtt ggaagttagt tgctagaaat
     2881 cctagattaa gactttttgt atcagcaaat ttattggaaa ttttttcaaa tacgatttgg
     2941 gtttcttcca ttatacttgt ttttgtaacg gagttattaa ataaaacgga aagttactgg
     3001 ggatattcta atacagcata ctctattggt attataatta gtggcttaat tgcttttagg
     3061 ctatctgaaa agttccttgc tgctaaatgg gaaagtattc tttttcctct tgtagctatg
     3121 gcaatagtga cactgactat tctatatttt ccaaacgcac agatgttttt attattttca
     3181 gctttagttg gtatgttatc gcaactaaaa gaagttcctg aaagtgtatt tcttcaggaa
     3241 acagtagagg aaaatcattt agttaatgtc tattccgttc ttgaagtgat ttctacatta
     3301 gcattttcag tatttgtttt gctaatgagc tatattactg agagttttgg tattagcatc
     3361 agtttttggc tatcagccat ttgtctgatg atagaagcta ttttaattta tatcagacga
     3421 gattatttta aatgagagag tggttaaaaa gtctttaaaa atcagaaaag cgcatagtat
     3481 caggtgttga aaaaacttga tattgtgtgt tttattatgg gaagatttac ttcattgtct
     3541 cctgaaatgg agttttgaag caggatcact ctatttgaaa atatacatag aaaaactgta
     3601 taatccttaa aataagctga aatctattgg aaacatacgg taaacaattg aaaagatact
     3661 atataaagtg gtacaatggt agaaaaataa gctagtaaga atcactctta ttttagcgaa
     3721 aaattacaga aatgaatggt ttttcttgat gaaacagaga aaagaattgt acctctttct
     3781 tggtcggaca gccttgtatt ttcttatctt tctagggctg ctttacttct ttagctatct
     3841 tggtcagggt caaggaagct ttatctataa tgaattttaa cttgaaggag aatccctatt
     3901 gtgtcaaata aaccaatagc agatatgatt gaaaccattg agcattttgc tcagacacag
     3961 cctagctatc ctgtctataa tgttttgggg caggaacaca cttatggcga tttaaaggct
     4021 gattcggata gtttggctgc agtcattgac caactaggct tgcctgagaa gtctcctgtg
     4081 gttgtttttg gtggccaaga atatgaaatg ttggcaacct ttgtagcgct gactaagtca
     4141 ggtcatgcct acattccaat tgatagccat tcggccttgg agcgagtttc agctatttta
     4201 gaagtagcag agccaagctt gattattgcc atttcagcct ttcccttgga gcaggtttct
     4261 acaccaatga taaatctagc tcaggttcaa gaagcctttg cccaagggaa caactatgaa
     4321 atcacgcatc cagtcaaggg agatgataat tactacatta tctttacttc tggtacgact
     4381 ggtaagccta agggagtgca gatttcacat gataatctcc tcagctttac aaactggatg
     4441 attacggata aggaatttgc gacaccgagt cgtccgcaaa tgctggcaca gccaccttat
     4501 tcttttgact tgtctgtcat gtattgggca ccgaccttgg cacttggtgg tacgcttttc
     4561 actcttcctt cagtcatcac tcaggacttt aagcaactct ttgcggctat cttttcattg
     4621 ccaatcgcta tctggacatc aacaccatcc tttgcagata tggccatgtt gtctgaatac
     4681 ttcaacagtg agaaaatgcc tggaatcacg catttctact ttgatggtga agaattgacg
     4741 gtcaaaacag ctcaaaaact gcgcgagcgt ttcccaaatg cccgtatcat caatgcttac
     4801 ggcccaacag aagcgacagt agctctgtca gcagttgccg tgacagacga gatgttagcg
     4861 actctcaaac gcctaccaat cggctatacc aaggctgatt ctccaacctt tatcattgac
     4921 gaggaaggaa ataaactgcc aaatggcgaa cagggagaaa tcattgtttc tgggccagct
     4981 gtttcaaaag gttatatgaa aaatcctgaa aaaacagcag aagccttctt tgagtttgaa
     5041 ggtctgccag cctatcacac aggcgatgtg ggaaccatga cagatgaggg cttgcttctc
     5101 tacggcggac gcatggactt ccagattaag tttaacggtt accgcattga gttagaagat
     5161 gtctctcaaa acctcaacaa gtctcgcttt atcgaatctg ctgtcgcagt accgcgctat
     5221 aacaaggacc acaaggtaca aaatctattg gcttatgtca tcttaaaaga cggtgttcgt
     5281 gagcagtttg agcgagatat cgatattacc aaggccatca aggaagacct gacagacatc
     5341 atgatgtcct atatgatgcc atctaaattc ctttaccgag acagtttgcc actaactcca
     5401 aatggaaaga ttgacatcaa aggattgatt aacgaggtga ataagagatg atggagtttt
     5461 ttcaacagct tcctcattta gagccatatg gcaatcctca gtattttgtt tatgtgattg
     5521 ctgcaacctt gcccatcttt ataggtctct ttttcaagaa acgctttgcc tggtatgaag
     5581 tgttggtaag tctcttcttt attgtcacca tgttggtggg tggaaagacc aatcaactag
     5641 ctgccttggg tatttacctt tgctgggaaa tattgctcct gcttttctac aagcattatc
     5701 gaaaaagcaa ggatggcaag tgggtcttct acttagttag ttttctgtcc ctacttccga
     5761 ttatctttgt caaggtgcaa ccagctatca atggaacgca gtctttgctt gggttcttgg
     5821 gaatttctta ccttaccttt cgttcggttg ggattatcat cgagctgaga gatggagtga
     5881 ttaaggattt taccctctgg gaattcctcc gtttccttct cttcatgcca actttctcga
     5941 gtggtccaat cgatcgcttt aagcgattta atgaaaatta tcaggctatt cctgagcgag
     6001 atgagttgat ggatatgctg gatgaatctg tccgctatat catgcggggc tttttgtata
     6061 agtttatcct agctcatgtt ttaggagaga ccttactacc tcctctgaag aatttagcct
     6121 tgcagtcagg tggcttcttt aatctctatg ccttggcagt tatgtatact tttggtctgg
     6181 agctcttctt tgactttgca ggttattcta tgtttgcttt ggccatctca aacttgatgg
     6241 gaatccgtag ccctatcaac tttaacaagc cctttttatc aagggattta aaggagtttt
     6301 ggaatcgctg gcatatgagt ctgtccttct ggttccgtga ctttgtcttt atgcgaatgg
     6361 tgatggtgtt aaccagaaag aaagtcttta aaaatcgtaa tgtaacctca agcatggcct
     6421 acattgtaaa tatgctgatt atgggatttt ggcatggtgt gacctggtac tatatcgcct
     6481 atggactctt tcatggacta ggcttggtca tcaatgatgc ctgggttcgc aagaaaaaaa
     6541 cgctcaataa ggaacggaaa aaagcaggga aggctgccct acctgagaat cgctggattc
     6601 agttgcttgg catggttgtc actttccatg ttgtcatgtt gtcattctta atcttttctg
     6661 gattcttgaa taatctatgg tttaaaaaat aaaaggaaat aaaatatgga tatcaaatca
     6721 gaagttattg aaattattga tgagttgttt atggaagatg tttctgacat gatggatgaa
     6781 gatctttttg atgcaggtgt cttggatagt atgggaacgg ttgagttgat tgtggagatt
     6841 gagaaccgtt ttgacattcg tgtccctgta acagagtttg gtcgtgacga ctggaataca
     6901 gctaataaaa tcatagctgg tattgtggag ctacaaaatg cttaaacgct tatggatgat
     6961 cttcggaccg gtcttgatcg ctggtttgtt ggtttttctg ctcattttct tttatcctac
     7021 tgagatgcat cataatctag gagctgaaaa gcgttcagca gtggctacta ctatcgatag
     7081 ttttaaggag cgaagtcaaa aagtcagagc actatctgat ccaaatgtgc gttttgttcc
     7141 cttctttggc tctagtgaat ggcttcgttt tgatggtgct catcctgcgg tattagctga
     7201 gaaatacaat cgttcctacc gtccttatct tttaggacag gggggagctg catcgcttaa
     7261 ccaatatttt ggaatgcaac agatgttacc acagctggag aataaacaag ttgtgtatgt
     7321 tatctcacct cagtggttca gtaaaaatgg ctatgatcca gcagccttcc agcagtattt
     7381 taatggagac cagttgacta gttttctgaa acatcaatct ggggatcagg ctagtcaata
     7441 tgcagcgact cgcttactgc aacagttccc aaacgtagct atgaaggacc tggttcaaaa
     7501 gttggcaagt aaaggagaat tgtcgacagc agacaatgaa atgattgaat tattggctcg
     7561 ttttaatgaa cgccaagcct ccttttttgg tcagttttcg gttagaggct atgttaacta
     7621 cgataagcat gtagctaagt atttaaaaat cttgccagac cagttttctt atcaagcaat
     7681 agaagatgtt gtcaaagcag atgctgaaaa aaatacttcc aataatgaga tgggaatgga
     7741 aaattatttc tataatgagc agatcaagaa ggatttgaag aaattaaagg attctcagaa
     7801 aagctttacc tatctcaagt cgccagagta taatgacttg cagttggttt taacacagtt
     7861 ttctaaatct aaggtaaacc cgatttttat cattccacct gttaataaaa aatggatgga
     7921 ctatgctggt ctacgagagg atatgtacca acaaacggtg cagaagattc gctaccagtt
     7981 agaaagtcaa ggttttacca atatagcaga tttttctaag gacggcgggg agcctttctt
     8041 tatgaaggac accattcacc ttggttggtt gggttggttg gcttttgaca aggcagttga
     8101 tcctttccta tccaatccca caccagctcc gacttaccat ctgaatgagc gctttttcag
     8161 caaagattgg gcgacttatg atggagatgt caaagaattt caatagataa tataatatag
     8221 aagagttcaa gaatgaaact agttttcacg ttttttcttg actctttttt tgcttgtgat
     8281 ataattaact ggtaaacaaa atgtcaaaga atagtatttt tctcttaaaa aagagaagtc
     8341 taaaaggaaa ggagtcagat atgagacagc tagcaaagga tatcaatgct tttttgaatg
     8401 aggtgatttt gcaggcggaa aatcagcatg aaatcctaat aggtcattgc actagcgagg
     8461 tggccctgac caatactcag gagcatatcc ttatgctctt gtcagaggaa tctttaacaa
     8521 attcagaatt ggcccgtcgt ctcaatgtca gtcaggcggc agttaccaag gccattaagt
     8581 ctttggtcaa ggaagggatg ttggaaacat ctaaagattc taaagatgcg cgtgtgattt
     8641 tttatcagtt gactgacttg gctcgtccaa tcgctgagga gcaccaccat caccatgagc
     8701 atacactttt aacctatgaa caagtggcga ctcagtttac tccaaatgaa caaaaagtga
     8761 ttcagcggtt tttgactgct ttagtaggag aaatcaaata atgagatata ttacggtaga
     8821 ggatttgtcc ttctattatg ataaggagcc tgttcttgaa catatcaatt atagtgttga
     8881 tagtggggaa tttgttacct tgactgggga aaatggagcg gctaagacga cgctcatcaa
     8941 ggccagtctt ggaattctgc aaccacgcat tggaaaggtg gctatttcaa agacaaatac
     9001 gcaaggtaag aaattgagaa tagcctatct tcctcaacaa attgccagtt ttaatgctgg
     9061 ttttccaagt acggtctatg aatttgtcaa gtcgggtcgt tatccgagaa aaggctggtt
     9121 ccgtcgtttg aatgctcatg atgaggagca tatcaaggcc agtctggact cagttggcat
     9181 gtgggaacat cgagacaaac gcttgggttc tctatctggg ggacaaaagc agcgagcggt
     9241 gattgcgcgt atgtttgctt ctgaccctga tgtgtttatc ctagacgagc cgacaacggg
     9301 gatggatgca ggaagtaaaa atgaatttta cgaactcatg catcacagtg cccatcatca
     9361 tggcaaggct gttttgatga ttacccatga ccctgaagaa gttaaggatt atgcggatcg
     9421 caatattcat ctagtccgta accaagactc gccatggcgt tgtttcaatg ttcatgagaa
     9481 tggccaggag gtgggccatg cttagtttat tatcttacga ctttatacaa cgcgcctttt
     9541 tggcggttat tgctatgagt cttttctcac cggtattggg aaccttcctc atcttgcgtc
     9601 gtcagagttt gatgagtgat acccttagcc acgtctcact ttcaggtgta gcctttggtc
     9661 tggttttggg gatttctcca actgtttcta ctattgccat tgtcttgatt gcggcggtct
     9721 ttctggagta tctccgtacg gtttacaaga gctttatgga aatcgggaca gctatcctca
     9781 tgtcaacagg tctggctgtt tctctgattg tcatgagcaa gggtaaaagc tcgagttcaa
     9841 tgagtttgga ccaatatctc tttggttcga tcgtgactat cagtgaagaa caggtcattt
     9901 ccctctttgt cattgcggcg gttgttttga ttttgacctt tctctttctt cgtcctatgt
     9961 atatcttaac ttttgacgaa gatacggcct ttgtggatgg cttgccagtt cgtaccatgt
    10021 ccattctttt taacatggtg acaggggtgg ctattgccct tatgattcct gcagcaggag
    10081 ctcttctggt atcgaccatt atggtcttgc cagctagtat tgccctgcgt ctggggaaaa
    10141 actttaaatc ggttatgctg cttgccagtg cgattggctt tttgggaatg gtagcaggac
    10201 tttacatttc ctactatgca gaaacacctg caagtgcaag tattaccatt atttttgtaa
    10261 ctgtctttat actaatcagt ttagtaagac gttttatcaa ataggagacg aacgtgaaaa
    10321 aaattagctt attactagcc agtctatgtg ccttgttttt agtggcttgt tccaatcaaa
    10381 aacaggcaga tggtaaactc aatatcgtga caacctttta ccctgtctat gaatttacca
    10441 agcaagtcgc aggagatacg gctaatgtag aactcctaat cggtgctggg acagaacctc
    10501 atgaatacga accatctgcc aaggcagttg ccaaaatcca agatgcagat accttcgttt
    10561 atgaaaatga aaacatggaa acatgggtac ctaaattgct agataccttg gataagaaaa
    10621 aagtgaaaac catcaaggcg acaggcgata tgttgctctt gccaggtggc gaggaagaag
    10681 agggagacca tgaccatgga gaagaaggtc atcaccatga gtttgacccc catgtttggt
    10741 tatcaccagt tcgtgccatt aaactagtag agcacatccg cgacagcttg tcagcagatt
    10801 atcctgataa aaaagagacc tttgagaaga atgcagctgc ctatatcgaa aaattgcaag
    10861 ccttggataa ggcttacaca gaaggcttgt ctcaagcaaa acaaaagagc tttgtgactc
    10921 aacacgcagc ctttaactat cttgccttgg actatggact caaacaagtc gcaatctcag
    10981 gcctttctcc agatgcagag ccatcagctg ctcgcttggc agaattgaca gagtatgtca
    11041 agaaaaataa aatcgcctat atctattttg aagaaaatgc ctcacaagcc cttgctaaca
    11101 cactttcaaa agaagcaggt gtcaaaactg atgtcctcaa tcctttagaa agtctgacag
    11161 aagaggacac caaggctgga gaaaactaca tttccgtgat ggagaaaaac ctcaaggctt
    11221 tgaaacaaac aacagaccaa gaaggcccag caatcgaacc tgaaaaggca gaggatacca
    11281 agacagtcca aaatggttac ttcgaggatg cagctgtcaa ggaccgcacc ttgagtgact
    11341 atgcaggtaa ctggcaatca gtttatcctt tccttgaaga cggcacgttt gaccaagtct
    11401 ttgactacaa ggctaagttg actggtaaga tgacccaggc tgagtacaag gcttactata
    11461 caaaaggcta tcagacagat gtgactaaga ttaacattac tgataatact atggaatttg
    11521 ttcaaggtgg acaaagcaag aaatacactt acaagtatgt cggtaagaaa attttgactt
    11581 acaagaaagg caatcgtggc gtgcgtttcc tatttgaagc cacagatgct gacgctggac
    11641 aattcaagta tgttcagttt agtgaccaca atatcgcccc agttaaggca gaacatttcc
    11701 atatcttctt tggaggcaca agccaagaag ccctctttga agaaatggac aactggccaa
    11761 cctactaccc agataaccta tctggccaag aaatcgccca agaaatgttg gcgcattgat
    11821 gagaaatcga ctagttcata agagctagtc ggttttttga tactagatgg ctaacttcat
    11881 tatagacctt tcagaactaa gggaacctga aaaaataaat aaaactcttg aaatatctgg
    11941 gcttatatgc tagaatgtag ttagtgtata aggttcatta gaacaccaaa gcccctaact
    12001 agtgccatag ttaagggctt ttttgacgta tcttagcgat ttaacgggtg tttataggct
    12061 agtcagtcgg tctacttctt accatctagc catttgcaga cgaaatacaa gataattcca
    12121 gctataacat ctgctataat agtaagagca agctctggta taaggctcat tagtttcacc
    12181 tcctctcacg aacccatagg aacgtaatcg gtaaccgatg acaaaagtat tataccacac
    12241 taaatttaga tcatcaacct cacttaatgc ttgaactatt gtagattata tgctaaaatg
    12301 tagttaattg ataaggttca ttagaacacc aaagccccta actatggccg tagttaaggg
    12361 cttttttgac gtatcttagc gatttaacgg gtgtttatag gctagtcagt cggtctactc
    12421 cttactatct agccatctgc agacgaaata caagataatt ccagctataa catccgctat
    12481 aatagtaaga gcaagctcta tgataaggct cattagtttc acctcctctc acgaacccat
    12541 aggaacgtaa tcggtaaccg atgacaaaaa tagtatacca caatacattt agatcatcaa
    12601 ggtcgcttaa ttcttgaaat atagggtcta ggcgacaaag tctttaaaat cagaaaaacg
    12661 cataatatca ggtgtgcaaa aacttgatac tatgcgtttt attgtgggaa ggtttactcc
    12721 attttctcct gaaattgagt ttttgtccag tctctgtttt tagggttgct aagaaaataa
    12781 tgtcatgtgg tgaatatttg taaatcagtc agcagacaga acgaatactc ttcgaaaatc
    12841 ttttcacatc atgtcagctt cgtctttccg tatatatgtg actgacttca tcagttctat
    12901 ctacaacctc aaaacagtgt ttcgagctga cttcatcaat tttcaaatct gtactttgag
    12961 caagctgaga ctagcttcct atttgatttt cattgaatat cagaaaccca ttctccatca
    13021 aataattcga ctgcgtctaa taatttttgg tctggcaagg tgtcagaaat aaaggttgtg
    13081 tatttggata ggggattaat tttaaaaaat ccagtcttgt aaaatttaga actatcaatc
    13141 agtaagatgg tttcatgggc tttgtcaata atattctttt ttgaaatagc ttggctgaga
    13201 gaagcttcat aaacatattg gtcatcaata cctcttgctg aacaaaatgc taaatcgata
    13261 ttaaaatgat ctaataaaga attttcctta tcatagttga ccacggaaca ggattgatgt
    13321 ttgacctcgc cagatgtgat aaagattttg gagctatctt taacagtttc agatagggtt
    13381 tgtgcagtat gtaaaccatt tgtaaaaata atcaaattat caagttcaga aagataggga
    13441 caaagttcgt agacagtagt actagaatct agatagatac acataccaga ccgaataaag
    13501 tctttagcga gactagcgat tagtcttttt tgcctagtac tttctccttc acgtatttga
    13561 tgagaaagtt caattgtgtt catagaggac agggtcacgt atccgtgctt tcttttgata
    13621 agaccttgat tttctaagaa aattaaatca cgacgtaagg tacttgtgct ggagaaagtg
    13681 atttctgcca gctcttttac ggcaattctt tttttctttt tgataatttc aatcaattca
    13741 agtacacgtt catcttttat cataagctcc tcctaattta tcatttcaac tatattatag
    13801 cacaaattgg aggaatttga attattttta tgaatattgg gttaacattt gaacattatt
    13861 caagtaagcg ttcacatatt gaaaaaataa aacgtgggga ttataataaa cttaatcaag
    13921 gacgaagaga gaagaaaaat ggaagcggtt ttagcaatag atttaggtgc gacttctgga
    13981 agagcaatcg ttggttacct ttctgaaaat aaactggtaa tggaagaaat aaatcgcttt
    14041 tctaatctac ctattagagt aaaagggcat ttatcttggg atattgactt tctactagct
    14101 aaaattcttg aaagtatccg cttggctaat actagttaca agattttatc tatcggtatt
    14161 gacacatggg gagttgattt tggactgatt gataatgaag gtaagctgtt attacaacct
    14221 gttcattatc gtgatgaaag aacaaaggga gtgttaaagg aaatatctga aatgactgaa
    14281 ttagaaaaac tgtattcaga gacaggaaat cagattatgg agataaatac cttgtttcaa
    14341 ctctttaagg cacgtcaaga atctcctgac tctttctata agaccaataa gattctttta
    14401 atgccagatt tgtttaatta tctcttgaca ggtaagtttg ctacagaaaa aagcattgct
    14461 tcaacaactc aattatttga tcctaggagt caaaattgga atcagaatat cttaaaacta
    14521 tttgaattgg attcatcttt acttcctgaa attgtttcag agggaaatgt tcttggaagg
    14581 ataaaaaagg agtatggttt aggcgatatt cctgttgtga atgtttgtag tcatgataca
    14641 gcaagtgcga ttgtctcagt acctaagaca gaaggtagtt tatttatttc atcaggtact
    14701 tggtctttgg ttggagtgga acttacttca ccgattctta ctaccgaatc cttcagttat
    14761 ggatttacaa atgaagtcgg taaagatgga gtgattacat ttctgaagaa ttgtacaggg
    14821 ttgtggatca tagaggaact aagacgttca tttgaacgaa gagggaaagc ctattctttt
    14881 gatgatatta ggacaatggt ggagaaagaa aaagaaaatc ttcctctgat tgatactgaa
    14941 tcaactgaat ttgcaacaga atctgatatg cacaagactt tgacagaata tctagcttat
    15001 catcatgaaa ctagagagtg gacagatgga caactattta agattgttta tgaaagccta
    15061 gctgaaacgt ataggaaagc gatagagtta ctagaagaac taactcataa ggtttataag
    15121 aggatatatg tgattggagg aggtgctaga gccagttact ttaaccaaat gattgctgat
    15181 agaactggta aagaggttct tacaggttcg actgagggta cagctgtggg gaatattgtt
    15241 gtgcagctca tagctatggg acaattaaaa gggatggaag aagctcacca tgttattgag
    15301 gagttcctac aattagagag ttattactcc caaaagaatt aaaaagattg agagtttgta
    15361 aatttgcctc cctccccctt cttaagtttt gtacaagaag gggggataat tggtgaattg
    15421 aaaaatattt agtgttttga tatgaggagg acaagaatgt cagatgtaaa acaagaatta
    15481 attaagtatg gcaagaagct agtagaaaca gatttgacga aaggaacagg tgggaatctc
    15541 agtgttttcg atcgtgaaaa acaattgatg gcaattaccc cgtcgggtat tgatttcttt
    15601 gaaatcaaag aatccgatat tgtagtgatg gatattaatg gaaatgttgt agagggagaa
    15661 cgcttgccat ctagcgaatg gtatatgcat ttgattcaat accaaactcg tgatgatatc
    15721 gatgcaatta tccatgctca tacaacttat gcaacagtat tagcttgtct cagagaacca
    15781 cttccggcta gtcattatat gattgcagtg gcagggaaag atgttcgggt agctgagtat
    15841 gcaacatatg gtacgaaaga attggctgtg aatgcagcta aagcaatgga aggtcgtaga
    15901 gcagttttac tagcgaatca tggaatttta gcaggtgcac aaaatttatt gaatgcattt
    15961 aatattgttg aagaagttga atattgtgca aaaatttatt gtttagctaa gaattttgga
    16021 gagccagtag ttcttcctga tgaggagatg gatttaatgg cagaaaaatt taaaacatac
    16081 ggtcagagaa aatagggagg atattaatgt taaaacatat accgaaaaat atttctccag
    16141 atttattgaa gactttaatg gaaatgggac atggagatga aatagtatta gctgacgcga
    16201 attatccttc tgcctcatgt gcaaataagc taattcgttg tgatggtgta aatattccag
    16261 aattattaga ttccattctg tatttaatgc cattagatag ttacgtcgat agttcaattc
    16321 agtttatgaa cgttgtttcg ggtgatgata ttcctaagat atggggtacc tatagacaga
    16381 tgattgaagg tcatggtaca gatcttaaaa cgattactta tcttagaaga gaagactttt
    16441 atgaacgtag taagaaagct tatgctattg ttgctacagg agaaacttca ctttatgcta
    16501 atattatcct taagaaagga gtagttgttg aaagagaaaa tgtttaatag aggaatttta
    16561 gttgccagtc atggtaattt tgctagcgga gctctcatga ccgcagaaat gtttgttggt
    16621 gagacaacaa atgatagagt taggacatta ggtttgatgc ctggagagaa tattgtagag
    16681 tttgaacatt attttaaaaa tcaagtaaat gaactgttag actcaaatca agaggttatc
    16741 gttttgactg acttgattgg aggaagtcct aataatgtgg ctttgtcacg gtttttaaat
    16801 ttggattcag ttgatattgt aacagggttt aatatccctc tcctagtgga attaatatca
    16861 agttatgatt caaaaatcaa tttagaagaa attgttcaaa atgctcaaaa tagtttgttt
    16921 aatgttaaac aacaacttaa cgtagaggag gaagaggatt tatgtctata gagtttgttc
    16981 gtattgatga ccgtctggta catggtcaag ttgtcactac gtggctaaaa aagtatgata
    17041 ttgagcaagt tatcattgtt aatgatcgca tctcagaaga taaaacacga caatctattt
    17101 taaagatttc tgcaccggta ggtttaaaaa ttgttttctt tagtgtaaaa cggtttgtgg
    17161 aagttttaaa ctctgtgcca ataaaaaaga gaacaatgct gatatataca aatccaaaag
    17221 atgtgtatga ttctattgaa ggaaatttaa aattggagta cctcaatgta ggacagatga
    17281 gtaaaacgga ggaaaatgaa aaggtaacgg gaggtgtagc tctaggtgaa gaagacaaat
    17341 attattttaa gaaaatagtt gataagggaa cgagagttga aattcaaatg gttcctaatg
    17401 ataaagttac aatgttggaa aaatttttat aaaaataatt taaggaggta cagtatatgc
    17461 tattcacaca agcattactg gtgacattag ttgggattat tgccactatt gactataatg
    17521 gaccgttatt tatgattcac cgtccgttag ttacaagtgc aatggttggc ttagtcttag
    17581 gagatttcac ccaaggtgtt cttattggtt cagctcttga attaacttgg ctcggtgtaa
    17641 caggtattgg aggttacact ccaccagata ctatttcagg tgcgattatt ggtactgcat
    17701 ttggtatttt gtctggtcaa ggagaaactg ctggtatcgc tatagcagtt ccaattgcag
    17761 ttgctaccca acagttggat gttcttgcaa aaactttaga tgtttatttt gtgaaaaaag
    17821 ctgataatga tgctaaaaac ggagattatt caaagatcgg tttttatcat tattcaagtt
    17881 tggttttaat cactttattt aaaattgtac caattttcct agctattatg cttggagggg
    17941 aatatgtggc agacttgttt gctaaggttc caccaatcgt tatgcaggga cttaactctg
    18001 caggtgcttt actaccttca attggttttg gtatgctttt aaatatgatg ctcaagaaaa
    18061 atatgtgggt attcttgttg attggattca tttgttctgt gtatggagga atgtcaacca
    18121 ttgggatctc actagttggt attgcggtag catacttcta cgatatgatt ggaagtaaac
    18181 cacaagaaac aacttcaagt agtgatgttg aggaggatct tgatctatga tgaataataa
    18241 agtaactaaa gttgaactta aaaaagtttt caaacgaagt tttatgtatg gttcttcatg
    18301 gaactatgag agaatgcaga acctaggttt tctatataca attcttccag tattgaaaaa
    18361 actataccca gacaaagatt cagcttctcc tgcaatgaaa cgtcaccttg agtttttcaa
    18421 tactcatcaa acagcggcac catttattct tggagttact tccgctatgg aagaacaaga
    18481 aggaaatgaa ggtgcagctt caattactgg tattaaagtt ggcttgatgg ggccgctggc
    18541 tggtctagga gatagtttgt tctggctgac actagttcct atctgtttta gtattggtgc
    18601 gtcttattct aaagacggcg gtgctttagg tatctttatc gccttaatat tgtttaatat
    18661 tattaatatt cctgttaaat atttcggttt gaaatatggg tatactaagg gttctagtct
    18721 tatccaagaa aataatacaa aaggaacatt gaatcgcgtt acgagtatgg cgacagcatt
    18781 agggctagta ctagtgggtg gtttgattcc atcaatggtt ggtattaatt ttggattaga
    18841 atttaaacag ggggaacttg ttatttctgt tcaagaaatg attacaaaat taattccagg
    18901 atttatccct atggctttga ctttattaat gtgtaaatta attagaaaag gaaagaatcc
    18961 ggttgtacta atctttagtg ttatggctat tggagttatc ctagttgttt taggaatttt
    19021 gaagtagtag aaagtgtgga ggtggtattt gggatatcac ctccattttg gaagagaggt
    19081 aaagagtgaa attatggtat aagaaagctg cctcaaattg gaatgaagcc ttgccgattg
    19141 ggaacggtca tttaggtggt atgatttatg gttcagctac aaaagaatgt attcaactaa
    19201 acgatgagac tatttggtat agaggaaagt cagatagaaa taatccagac tcactattgc
    19261 atcttaaaaa aattcgggaa tatcttttag atggagaaat tcagaaagcc gaagaattga
    19321 taaagttaac aatgtttgct accccaagag atcaaagcca ctatgaatta cttggggaac
    19381 tttacattga gcatatagat attcagtctt gtgctctttc attgtatgaa agagagctag
    19441 atttagatac agctatttct aatgttgtgt ttgatcctaa tagttgtaat ttacaaataa
    19501 aaagagaata ttttacgagt tttaataaga atattttatg ttgccgtata gtgtcatcag
    19561 ttcaaaacac attaaattta aacattaatt tgggtagaaa taaacggttt aatgacgaag
    19621 tatctaaact ggattcaagt acaattttaa tgtcggcctc tgctggaggt agaaaaggtg
    19681 ttcagtttaa agtagtatgt cattctaaag ttacggatgg tgaagtaagt gtattgggag
    19741 agacaatagt tattcggaat gctacagagg tatttcttta tctcaaatca atgacgaatt
    19801 attggggaaa tatagatatt tcttctcttc agggagaatt tagtagtatt gattacttta
    19861 cagaaaaaga tgaacatgta aaaaaatatc aggagcaatt taatagagtt gattttaaac
    19921 tagactatag taaagattgt cttagcattc caacgaatct acttcttgaa aacactaaaa
    19981 agtatagtaa ctacttgact aacttgttat ttcattatgg aagatatctg ttaatatcgt
    20041 ctagtcaacc gaatggttta cctgccaatc ttcaaggaat atggtgtgat gaattaaatc
    20101 caatttgggg ttctaaatat acgattaata ttaatactca aatgaattat tggatggtag
    20161 gtccatgtga tttaccagaa gtagaatatc cattatttga tatgctcgaa agaatgagag
    20221 aaccgggaag actaaccgct aagaaaatgt atggagctag aggttttaca gcacatcata
    20281 atacggatgg ttttggcgat acggctcccc aatctcatgc catgggggct gcaatttggg
    20341 tattaactat tccatggtta tgtactcata tttgggaaca ctatttatat ttccaagatg
    20401 agcgtattct tacggaacat tttgaaatga taaaagaagc atttcttttc tttgaagatt
    20461 atttatttga ggtggatggc tacttgatga caggtccaag tgtctcacca gaaaataaat
    20521 atcgcttaaa aaatggtatt gaaggaaatg cttgtctatc atctacaatt gataatcaaa
    20581 ttctaagata tttttgtgat tcatgcattg gcattgcaaa acaattagga gacaattcgg
    20641 attttattag tcgtgtgaag gagttaaaaa agaaactacc taaaacaaaa ataggtagta
    20701 atgggcaaat ccaagaatgg ttagaagatt atgaagaagt agagcctggg catagacaca
    20761 tttcacctct atttgggctt tatccttata atgagattga tattcataaa actccggaat
    20821 tagcagaagc agctaaaatc actatcaata ggagattatc aaacgctaac tttttatctt
    20881 cacaggagag ggagcaagcg attaataatt ggttagtaag tggtttgcat gctagtacac
    20941 aaacaggttg gagtgctgca tggctgattc atttttttgc gagactatat caaggtgaac
    21001 ctgcttataa ccagattaat ggtttgttaa ataatgcgac tcttggcaat ttatttcttg
    21061 accatccacc atttcaaatt gatggtaatt taggtttggt gagtggaatt tgtgaattat
    21121 tagtacagag ccatcataat tggttatcac taattccagc tttaccttct gcttggtcag
    21181 aaggagaagt gaaaggtttc agagtaagag gaggatataa ggtatcgttt gcttggaaaa
    21241 acggggatat aacattccta aaattggaag gaggaaacaa agatcaaaaa gtaagagtaa
    21301 gaatatatgg caaaaatact gatgtacaaa atattgaatt ggtatttaat tcagaaaaaa
    21361 ttattgagtt aaatttttag gtataagtca tgaataaaga aaaaataaaa agaaaattaa
    21421 tcacaatact gtttgtatgt attgggatgt tatgttttgg attgttagca ggagttaagg
    21481 ctgataatcg tgttcaaatg agaacgacga ttaataatga atcgccattg ttgctttctc
    21541 cgttgtatgg caatgataat ggtaacggat tatggtgggg gaacacattg aagggagcat
    21601 gggaagctat tcctgaagat gtaaaaccat atgcagcgat tgaacttcat cctgcaaaag
    21661 tctgtaaacc aacaagttgt attccacgag atacgaaaga attgagagaa tggtatgtca
    21721 agatgttgga ggaagctcaa agtctaaaca ttccagtttt cttggttatt atgtcggctg
    21781 gagagcgtaa tacagttcct ccagagtggt tagatgaaca attccaaaag tatagtgtgt
    21841 taaaaggtgt tttaaatatt gagaattatt ggatttacaa taaccagtta gctccgcata
    21901 gtgctaaata tttggaagtt tgtgccaaat atggagcgca ttttatctgg catgatcatg
    21961 aaaaatggtt ctgggaaact attatgaatg atccgacatt ctttgaagcg agtcaaaaat
    22021 atcataaaaa tttggtgttg gcaactaaaa atacgccaat aagagatgat gcgggtacag
    22081 attctatcgt tagtggattt tggttgagtg gcttatgtga taactggggc tcatcaacag
    22141 atacatggaa atggtgggaa aaacattata caaacacatt tgaaactgga agagctaggg
    22201 atatgagatc ctatgcatcg gaaccagaat caatgattgc tatggaaatg atgaatgtat
    22261 atactggggg aggcacagtt tataatttcg aatgtgccgc gtatacattt atgacaaatg
    22321 atgtaccaac tccagcattt actaaaggta ttattccttt ctttagacat gctatacaaa
    22381 atccagctcc aagtaaggaa gaagttgtaa atagaacaaa agctgtattt tggaatggag
    22441 aaggtaggat tagttcatta aacggatttt atcaaggact ttattcgaat gatgaaacaa
    22501 tgcctttata taataatggg agatatcata ttcttcctgt aatacatgag aaaattgata
    22561 aggaaaagat ttcatctata ttccctaatg caaaaatttt gactaaaaat agtgaggaat
    22621 tgtctagtaa agtcaactat ttaaactcgc tttatccaaa actttatgaa ggagatgggt
    22681 atgctcagcg tgtaggtaat tcctggtata tttataatag taatgctaat atcaataaaa
    22741 atcagcaagt aatgttgcct atgtatacta ataatacaaa gtcgttatcg ttagatttga
    22801 cgccacatac ttacgctgtt gttaaagaaa atccaaataa tttacatatt ttattgaaca
    22861 attacaggac agataagaca gctatgtggg cattatcagg aaattttgat gcatcaaaaa
    22921 gttggaagaa agaagaatta gagttagcga actggataag caaaaattat tccatcaatc
    22981 ctgtagataa tgactttagg acaacaacac ttacattaaa agggcatact ggtcataaac
    23041 ctcagataaa tataagtggc gataaaaatc attatactta tacagaaaat tgggatgaga
    23101 atacccatgt ttataccatt acggttaatc ataatggaat ggtagagatg tctataaata
    23161 ctgaagggac aggcccagtc cctttcccaa caccagataa atttaatgat ggtaatttga
    23221 atatagcata tgcaaaacca acaacacaaa gttctgtaga ttacaatgga gaccctaata
    23281 gagctgtgga tggtaacaga aatggtaatt ttaactctgg ttcggtaaca cacactaggg
    23341 cagataatcc ctcttggtgg gaagtcgatt tgaaaaaaat ggataaagtt gggcttgtta
    23401 aaatttataa tcgcacagat gctgagactc aacgtctatc taattttgat gtgattctat
    23461 atgacaataa tagaaacgaa gttgctaaga aacatgttaa taatttgtcg ggtgaatctg
    23521 ttagtctaga tttcaaagaa aaaggagcaa ggtatattaa agttaaatta ctaacgagtg
    23581 gagtgccttt gagtttagca gaagtagagg tttttagaga atcagatggt aagcaatctg
    23641 aagaggatat agataaaata acagaagata aagtagtctc tacaaataag gtagctactc
    23701 aaagttcaac caattatgag ggtgtagctg ctttagcagt tgatggtaat aaagatggag
    23761 attacggaca tcattcggtg actcatacta aggcagattc taacgcttgg tggcaggtcg
    23821 atctgggaga agagtttacg gtttctaaag ttgatattta taatagaaca gatgccgaac
    23881 ctcagcgttt atctaatttt gatgttattt ttctatcttc atcaggagaa gaagttttta
    23941 gaagacattt tgataaagta gttgatggtt tgttatcttt aaaagtacct tctgtagggg
    24001 ctaagctagt caaaatagaa ttaaaatcag cagctattcc gttaagttta gcggaagttg
    24061 aagtctatgg ttcaaagaga actccgaaga aactttctaa tattgcatta accaaagaaa
    24121 ctcgacagag ttcaacggat tacaatggtt tttctcgtct agcagttgat ggaaataaaa
    24181 acggagatta tggtcatcat tcagtgactc ataccaaagg agattctcct tcatggtggg
    24241 agatagattt agcacaaacc gaagaattag aaaagttaat tatttataat agaacagatg
    24301 ctgaaattca gagattatca aattttgata ttattatata tgattcaaat aatcatgaag
    24361 tttttaaaca acatattgac agtttagaaa gcaataatct atccatagac ttaaaagggc
    24421 tgaagggaaa aaaggttaga atttctttga gaaacgcagg aattccttta agtttggcag
    24481 aggtagaggt ttatacttat aagtaatttt aaaaattatc atcggtagta tgaaagaaac
    24541 agaaaaataa gaggaaaata gtatgattca acatccacgt attgggattc gtccgactat
    24601 tgatggtcgt cgtcaaggtg tacgcgaatc acttgaagtg caaacaatga acatggctaa
    24661 aagtgtggca gatttgattt caagcacatt gaaatatcca gatggggaac ctgtggaatg
    24721 cgtgatttct ccatctacta ttggccgtgt accagaggct gcagcttccc atgagttgtt
    24781 taaaaaatca aatgtttgcg caacaattac agttacacca tgctggtgtt atggtagtga
    24841 aactatggat atgtctccag atattcctca tgctatttgg ggatttaatg ggacagaacg
    24901 cccaggagct gtctatcttg cagctgtact agcttcacat gctcaaaaag ggattccagc
    24961 ctttgggatt tatggtagag acgtccagga agctagtgat acagctattc cagaagatgt
    25021 caaagaaaaa cttttacgtt atgcgcgtgc agctcttgca actggcttga tgagagacac
    25081 tgcttaccta tcaatgggta gtgtttcgat ggggattggc ggttctattg taaatccgga
    25141 tttcttccaa gaatacttag gaatgcgaaa tgaatcggta gatatgacgg agttcacgcg
    25201 ccgtatggac cgtggtattt acgaccctga agagtttgaa cgtgctatgg tttgggtaaa
    25261 agaacatatc aaagaaggag ttgaccgaaa tcgtgaggat ttgattcttt ctaaagaaga
    25321 gaaagaaaaa caatgggaat ttgttattaa gatgttcatg attggacgtg acttaatggt
    25381 tggtaaccca agacttgctg aacttggttt tgaggaagaa gcagttggtc accatgcttt
    25441 agtagctggt ttccaaggtc aacgtcagtg gacagaccat ttcccaaatg gggactttat
    25501 ggaaactttc ctcaatactc agtttgactg gaatggtatt cgaaaaccat ttgtatttgc
    25561 gacagagaat gattcactaa atggtgtgtc tatgctcttt aattatctat taacaaatac
    25621 tccacaaatc tttgctgatg tgcgcactta ttggagtcca gaggctgtta aacgtgtaac
    25681 gggacatact ttagagggtt gtgctgcagc tggcttctta catctaatca actctggttc
    25741 ttgtacattg gatggtacag ggcaagctac tcgagatggc aaacctgtta tgaaaccctt
    25801 ctgggagttg gatgaaagtg aagtgcaggc tatgcttgaa aatacagact tcccaccagc
    25861 aaaccgcgaa tacttccgtg gaggaggatt ctcaactcgt ttcttgacga agggggatat
    25921 gccagtaaca atggtacgtc tcaatcttct aaaaggggtt ggtccagtgc tacaaattgc
    25981 agaaggttat acacttgaac ttcctgaaga tgttcaccat actttagata atcgtacaga
    26041 tccaggatgg ccaactactt ggtttgctcc acgtttgaca ggaaaaggtg ctttcaagtc
    26101 tgtctatgac gtcatgaata attggggagc taatcacgga gccataacat atggccacat
    26161 tggagcagac ttgattacct tggcttctat gttgagaatt cctgtcaata tgcataatgt
    26221 acccgaggaa gatatcttta gacctaaaaa ttggtcctta tttggaacag aagatctaga
    26281 atcagcagac tatcgtgcat gtcagttgtt gggaccgcta cataaataaa aattgtgtat
    26341 ataggaggtg aacttatgtc cctcctatcc ttttaaaaag atttgttaaa caattcacaa
    26401 ataattgaaa acgaatacaa aaactaatat aatgatgtta aatagatagc gcggaggcgc
    26461 aggaggaaaa ttatatggct acattttatg ttccggcagt caaccttatt ggtaaaggtg
    26521 ttgtaaatga agtgggtcct tatatcaagg aacttggcta taaaaaggca cttttggtga
    26581 cagataagta catcgaaggc agtgacattt tacctaaggt tttaaaacca ctggatacag
    26641 aaggaatcga atatgtcatc tttagcgatg tagagccaaa ccctacttgt aagaatgtca
    26701 cagatggggt agctgctttg caagaacatg gatgtgattt tatcatcagt cttggtgggg
    26761 gttctccaca ggatgcagct agttgtattt ctatcatggc tacaaatggt ggaaaaccac
    26821 aggattatga agggcttcat aagtctgcta aaaaaggctt gccagttgtg gctatcaata
    26881 caacggcagg aacttctgca gaaatcacta ttaactatgt gattactgat gaagaacgca
    26941 aggttaagat ggtaatggtt gacaagaata gccttgctct tatctctgtt aatgacccgg
    27001 aactcatgct ttccaaacct aaaggcctga ctgctgctac tggtatggat gctctgactc
    27061 acgctgttga agctttggta acacctggtg cttatgatgt aaccaagaaa ctgtctattg
    27121 gtgctattga gcttatcaag gaatatcttc ctcgtgctgt agaaaatgga tacgatattg
    27181 aagcgcgtga aggtatggtc aatgccatct tccttggtgg tatgagcttt aataatgctg
    27241 gtcttggtta tgttcactca atggctcacc aactcggtgc agtatataat ttgccacatg
    27301 gtgtttgctg tgccatgttg ctaccagtta tagaacgtga aaatgctaaa cgtgtaccag
    27361 aagctttccg caatgttgcc aaagccttgg gccttcatgt ggaaggtaaa tcagatcaag
    27421 agtgtgccga ttatgcgatt gctgagattg agaagctttc tgagacagta ggtattccta
    27481 agaaattgac tgaacttggt attgaagaaa aagatttcga ctttgaatac ctttctaaga
    27541 atgccttgat tgatgcctgc gcaccaggaa atccatttat gccaacctta gaagaaacga
    27601 ttgcctttta taaagagtta ttttagcaag agattagacg acaataggac aattcacctc
    27661 taattattga catttcagga aaaatcgcag taaaaacggc acagccttct ttaaatgtgc
    27721 tataatacta gaaaaatact tgtggaggtt ccattatggc aatatttttc atgatttttc
    27781 tgattgtttg tgtgctccta ttggtgatag tcacactgag tacagtttat gtggttcgtc
    27841 agcagtcggt ggcgattatt gaacgctttg ggaaatacca aaaggttgct aatagcggta
    27901 ttcatattcg cttgcctttt gggattgact cgattgcagc acggattcag ttgcgcttgt
    27961 tgcaaagtga tattgtggtt gagactaaga ccaaggacaa tgtgttcgtt atgatgaatg
    28021 tagcgactca gtaccgtgtc aacgagcaga gcgtgacaga tgcttactat aaactcatac
    28081 gtccagaatc tcagattaaa tcttatatcg aagatgctct tcgctcttct gttccaaaat
    28141 taaccttgga tgaattgttt gagaaaaaag atgagattgc ccttgaggtt caacaccaag
    28201 tagcagaaga aatgaccact tacggctaca ttatcgtgaa aaccttgatt accaaggtcg
    28261 aaccagatgc agaagttaag caatctatga atgaaatcaa tgcggcgcaa cgtaagcggg
    28321 tcgcagcaca agaattggcg gaagctgaca agattaaaat tgtcactgca gctgaagcag
    28381 aagcagaaaa agaccgcctt catggtgtgg ggattgctca acaacgtaag gcgattgtgg
    28441 atggattggc agagtctatc accgaactca aggaagccaa tgttggcatg acagaagaac
    28501 aaatcatgtc tatcctcttg accaaccagt atttggatac cttgaatacc tttgcctcta
    28561 aaggaaatca aaccatcttt ttaccaaata cgccaaatgg tgtggatgat atccgaacac
    28621 aaatcttgtc agcccttcgc gctgagaaga aataatagac taatactctt cgaaaatctc
    28681 ttcaaactac gtcagcgtcg ccttgccgta tatttgagct gacttcgtca gttctatctg
    28741 caacctcaaa acagtgtttt gagctgactt cgtcagtctt atctactacc tcaaaacggt
    28801 gttttgagca acctgtggct agtttcctag tttgctcttt gattttcatt gagtataaag
    28861 agcttggcaa caggctcttt ttgtattgcg tttattaaga aaaacaaaaa acatcgatat
    28921 acatttaact aaaaattatt gtatgttatc tcccttaatt aggaatgata agggaataac
    28981 tagaaagatt tgtgaataca aactatttct gatatacaaa atatacagta ataatgaatg
    29041 atgggagatg ggatgaaaga atttcaattt gagagaaagc agcgtttttc tttgaggaaa
    29101 tatgtaatag gagcttgttc ggtcttgcta ggaacgagtt tattttttgc tggtatgggt
    29161 gctcagcctg tacaggatac agaaacgagt tcagcactaa tttcaagtca ttatttggat
    29221 gagcaggatt tatctgaaaa gctgaaatct gagttgcaat ggtttgaatt agaaaacaag
    29281 cttttgaact tatgggagta ttaggttact atgaaggatt tgttccttat gtttcaaatc
    29341 aatacaaaaa ccaagctgaa gaagaaggca aaccgctatc tgataaatat attttcgaaa
    29401 aaatcttagg aaaaacatat gcagccttca aaaaagatca aattaatgag cgtgtcgaga
    29461 aattaggtaa gttaaaacct attacaataa attacaacgg aaaataagaa gtaattgata
    29521 gtaaagaaaa attacaagag cttatgaata aagccgttaa agacgaagtg gctcaaatat
    29581 agtaaaatga aataagaaca ggataaatcg atcaggacag tcaaatcgat ttctaaaaat
    29641 gttttagaag tagaggtgta ctattctagt ttcaatatac tataaaatca ggcaatacca
    29701 cggctaaaaa gtttgagttt atcgaaacac cagtgcaaaa actgaaaaaa tcgatttata
    29761 aagctcatct caaagattca gat
//
LOCUS       DAVHSY010000024        25214 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.024, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000024 DAVHSY010000000
VERSION     DAVHSY010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25214
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.024"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            11..1147
                     /gene="dnaN"
                     /locus_tag="VVR43_001283"
     CDS             11..1147
                     /gene="dnaN"
                     /locus_tag="VVR43_001283"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU6149644.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            1212..1406
                     /locus_tag="VVR43_001284"
     CDS             1212..1406
                     /locus_tag="VVR43_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU6149645.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(1730..2149)
                     /locus_tag="VVR43_001285"
     CDS             complement(1730..2149)
                     /locus_tag="VVR43_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEU6149646.1"
                     /translation="MTPEQVKETLEGVKWINKEIEGLYLELATLESGIIKKQELSNTR
                     VQTSRVNTAENNLISVLKLKEDTLQRIERLTEERMEISRLIDKLANPLERSVLRLFYL
                     NVLEAWQVAEEIDRSKTTVYLIRQKAIEHLAGLVHAD"
     gene            complement(2768..3019)
                     /locus_tag="VVR43_001286"
     CDS             complement(2768..3019)
                     /locus_tag="VVR43_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149647.1"
                     /translation="MKAIKNRLNKLNKLAVVDEVDTVFLTQIDTGHFEVRYRIGGKNP
                     KDIIEVYPTKEEAEKAISEIKNTKGLRIFWDNLALLEDN"
     gene            complement(3006..3347)
                     /locus_tag="VVR43_001287"
     CDS             complement(3006..3347)
                     /locus_tag="VVR43_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000035041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEU6149648.1"
                     /translation="MANYLMTGNVKKASELSEITRKTAYNYLNDATFKRIYRERRSEQ
                     LKESTTLLQNASVEAVNVLREIMLDKTVSPYARQQSAQSILNMAYKAVEMVEVVEQLE
                     ILEAKILDEGD"
     gene            complement(3398..3664)
                     /locus_tag="VVR43_001288"
     CDS             complement(3398..3664)
                     /locus_tag="VVR43_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149649.1"
                     /translation="MVRSLKARLEKLEEYAGKTEYATTDECISLYVDCLRFAFQQDEI
                     KIDMDDFIKTPFKDIKLADYKKSKKRMDELREMTGISEFSELEQ"
     gene            complement(3727..4251)
                     /locus_tag="VVR43_001289"
     CDS             complement(3727..4251)
                     /locus_tag="VVR43_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149650.1"
                     /translation="MTLKTFSDKAKTFNFTYEFKDQDTAQVAGSALMGYMIGTYVVPS
                     ISITYKNKGTLVAEYVEDHKLNKTFKRIRDGFKDYYKQPVNDEAFEERYKRERVLQLK
                     ESEDFESLLNKVTDYELKLLDYAERLLSDKPILMDSMTAFGTLEMLGNESINLFQKLD
                     VEGEYKGLADYSGQ"
     gene            complement(4344..4541)
                     /locus_tag="VVR43_001290"
     CDS             complement(4344..4541)
                     /locus_tag="VVR43_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149651.1"
                     /translation="MAMNICQRVIRLEETVERISEALDGFIENANHNAIVSNKNIERI
                     QESFEIVFKELDELKAVPDKH"
     gene            complement(4861..6315)
                     /locus_tag="VVR43_001291"
     CDS             complement(4861..6315)
                     /locus_tag="VVR43_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HEU6149652.1"
                     /translation="MWELYSRIWELGDQWRKENSYIVNEGKKNERVEIPRPSVAIVAK
                     ALQEICHFTFIGEGVISDISKLYLYHLDLGHYVSSNDIFRKLLLKYDSRLTSNKFFLE
                     LISYIRTETKMKPPLDDYRYIPVANGVYNIKTHKLEEFSPNFVITSKIQTEYNPCARK
                     PILDGWFDFDRWLEALAVNDKEVVALLWQVINEAINPNRTRKKMVLMVGDGNNGKGTF
                     QALLENLIGRSNISNLKPDQFGKEFYLGALEGKVCNIGDDISNKYLDEVSDLMSVISG
                     DPVQVNKKSLQPVEARFRLLCIFSGNDLPRARNKTMGWYRRLCIIPFRADFNGQKERH
                     EIKDRFIKNKELLEWVLFKVLNMPDFDSFIEPEAVQKMLSKYKNDNDYIKVWVENFYI
                     PNGWHEINHVPMFIARNKLKEFAEDIGIDKPKLGQFSNAVMAELEKTTSYKYSAKNGT
                     VSSKFYDVLDPQGFQRKRFVKGIWGIHLEDEDLG"
     gene            complement(6395..7255)
                     /locus_tag="VVR43_001292"
     CDS             complement(6395..7255)
                     /locus_tag="VVR43_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEU6149653.1"
                     /translation="MTIYEARGFQSNLVYPFDKIEPFQYIERFKPLVVPESADPEEYK
                     RTQAPYCLSGKVMPEKNGSYKRNNTSLIYRDLIFLDYDDIQGTTEDFIEAVSSALFGY
                     SYILYPTIKHSIEKPRFRLVVKSNNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPATYQKIVEHGLDYPVPKVEPRAKQGTTERYKPRVSGQRSMTMRIIDTLF
                     NGFGDEGGRNVALTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTFSS
                     IARAEYRKRG"
     gene            complement(7252..7524)
                     /locus_tag="VVR43_001293"
     CDS             complement(7252..7524)
                     /locus_tag="VVR43_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149654.1"
                     /translation="MFSLSRESEQDLAHGILEVVERYLEAREKVPPRLTKLINRVELK
                     EELKISDNTLNKWESQGLRRYQPPDDGSRMIYYLVTDIWKFLGVDE"
     gene            complement(7517..7858)
                     /locus_tag="VVR43_001294"
     CDS             complement(7517..7858)
                     /locus_tag="VVR43_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU6149655.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGSEISLTTKLTERTVRDIIKR
                     LVVKHNIPIVGVRCGVFSGYFIPANKGELLDGAKAFYNQVQEESKRLAVLMNSDLESY
                     KETLKEVGGYV"
     gene            complement(7839..8132)
                     /locus_tag="VVR43_001295"
     CDS             complement(7839..8132)
                     /locus_tag="VVR43_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149656.1"
                     /translation="MSYIVKIYLDSEKIPDEPYFTKEIFLATCMGNATKLAVTMGLLT
                     KQALDLETKTAILKALDTIIETQKAILQGVASGQITFVNKSKGEEGLDESIRE"
     gene            complement(8129..8344)
                     /locus_tag="VVR43_001296"
     CDS             complement(8129..8344)
                     /locus_tag="VVR43_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149657.1"
                     /translation="MNELDISNTQAAVLIVILIGLLLYLNHRDRKKSAQIERENQQTI
                     KTPSEDLNPEYGRYIQLAGVNVWGGME"
     gene            complement(8337..8603)
                     /locus_tag="VVR43_001297"
     CDS             complement(8337..8603)
                     /locus_tag="VVR43_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149658.1"
                     /translation="MTKEEIRNILDELDDLTLGLNTAENAFDATFHFFSKNISTKEKT
                     MLLTLEYDTQSAIFNLAYDCLINAKENLVNTIRMYRKELEEKHE"
     gene            complement(8621..8761)
                     /locus_tag="VVR43_001298"
     CDS             complement(8621..8761)
                     /locus_tag="VVR43_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149659.1"
                     /translation="MILDLGKMTQAEFDEVMADIKARNPNLLQLITDFLDRKVTPEEV
                     DD"
     gene            complement(8773..9273)
                     /locus_tag="VVR43_001299"
     CDS             complement(8773..9273)
                     /locus_tag="VVR43_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149660.1"
                     /translation="MISDKLEAISTNLEEIQKSLVGAETALAKREISRVLNDLDDVYS
                     ELTSTEYHEQQQTIKEQTERMKQRVIAEVIGELEEREESYYRNFWGDTQFIKLLSNFD
                     GFLFLNTYLAEITKENTYPMEQSQLLNYVWELIAVDIAKKKRGKKNVLDSWTDSSLYT
                     RGMMID"
     gene            complement(9270..9410)
                     /locus_tag="VVR43_001300"
     CDS             complement(9270..9410)
                     /locus_tag="VVR43_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149661.1"
                     /translation="MEETTYDIIAKSLDRISMELHQADENNDFSRIWVLSGQLKGQWR
                     KT"
     gene            complement(9675..9824)
                     /locus_tag="VVR43_001301"
     CDS             complement(9675..9824)
                     /locus_tag="VVR43_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149662.1"
                     /translation="MTNYDRAKRFYSRATYVLSDFLHGRIDEQEFRKQWQRLADKAVN
                     ETKKN"
     gene            complement(9811..9957)
                     /locus_tag="VVR43_001302"
     CDS             complement(9811..9957)
                     /locus_tag="VVR43_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149663.1"
                     /translation="MEQYTKRASALIITFNRGVISQDEFIEEFTKLREKVVKAVSEAK
                     NDKL"
     gene            complement(9961..10389)
                     /locus_tag="VVR43_001303"
     CDS             complement(9961..10389)
                     /locus_tag="VVR43_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149664.1"
                     /translation="MRKKHQVVKFKDIAEKLPELEGKRLEEITKVLGYRNLESCRTNL
                     CKLKQNNRLDFTLEKGVYSKFALLDGTVKEELEDKELSERGRYLKSVDRYKAMLNAFS
                     IAFDSTVKAETRQKAEHDGLKALDRIPDKHYALLYDMMEG"
     gene            complement(10543..10716)
                     /locus_tag="VVR43_001304"
     CDS             complement(10543..10716)
                     /locus_tag="VVR43_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000130088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU6149665.1"
                     /translation="MTDKIKKVGRPKGENSNTVKLTVRVSEQLNSKLEEYGKKNGLTK
                     PETLRKAFENLTK"
     gene            complement(10955..11203)
                     /locus_tag="VVR43_001305"
     CDS             complement(10955..11203)
                     /locus_tag="VVR43_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149666.1"
                     /translation="MENEFKTVTNAKGVEIPKYFKDFKKLVEMDRQLAEYLCMNYELL
                     DSEDLGAFLETVEQGFSWILELIESKDLLYSPQTGKKA"
     gene            complement(11215..11820)
                     /locus_tag="VVR43_001306"
     CDS             complement(11215..11820)
                     /locus_tag="VVR43_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEU6149667.1"
                     /translation="MELVYMDGKKEPYTTSEIIAECAGVTHHTIQELLRKHKADFESY
                     GIIAFEMRKLDGRGRPMKIYRLNEQQATLLITYLRNTEPVRKFKMNLVKAFFEMRDEL
                     SKRYLQRELEKPKRKTLTEAIKSWEKAPQHAYSTLTNLLLKGATGKNKAQLMQERESE
                     NGIDSLTSAELTNYQRLEDMAIAMINLNMRYSEIKELIFKV"
     gene            complement(11842..12219)
                     /locus_tag="VVR43_001307"
     CDS             complement(11842..12219)
                     /locus_tag="VVR43_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149668.1"
                     /translation="MLYHWGLTFSEEISDLEHKGENNMNNKQVYQAQTTDHGIARALG
                     EEIRMITDVEETTYNGHGEIIVEYTSDVALTKLFDRIKALYEKGESYETKTFLHFKVL
                     EDDIEPSPNGVFTAKEVAEFLGI"
     gene            complement(12294..12485)
                     /locus_tag="VVR43_001308"
     CDS             complement(12294..12485)
                     /locus_tag="VVR43_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001241280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6149669.1"
                     /translation="MRLTLKALRANSNMKQSEVAQKLGISTTTWSKWENGKSFPDVAQ
                     VKEIEKLFGVAYDDIIFLS"
     gene            12689..13405
                     /locus_tag="VVR43_001309"
     CDS             12689..13405
                     /locus_tag="VVR43_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6149670.1"
                     /translation="MADNIKRLLSAKGLNPRQLAIALDFKYTTVNDWVNAKTYPRIDK
                     IEMLANFFNVSKSDLVENKNAETPTTSLIQSIYDQLTPPRQAKALTYLKKQLLEQKNE
                     NIVSENIISLDDYRESKTLPVIGVVTAGNGITQDDNLNIEKCFYTDEIPDDYDAIAYV
                     VGNSMEPKIKNGDYLFIKNTPQVDYNTIGIFQVDGANYVKKLRQGYLESLNPDCADIQ
                     LDESNDIRTIGEVVGIYREK"
     gene            13424..14092
                     /locus_tag="VVR43_001310"
     CDS             13424..14092
                     /locus_tag="VVR43_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000666925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HEU6149671.1"
                     /translation="MKFCPECGNSVVGCKFCPNCGYSINASLKTTPQKVATPSSRPST
                     VRSKRTDKVGPLEIDKNHRTYRIHGARKAKGSSGLIGGTAKVVGKTTLALGTGGLSLI
                     PSLIKKDKNDTDWYSFDDLVSYELVINDQSVVSGGVGQALVAGAVFGVIGAVAGGIVA
                     KRKATTKILNMTIRITSNDFTKPVVFIDLIKKPVKNTSKEYKEAIENAQKIIGALDVI
                     THNS"
     gene            14231..14899
                     /locus_tag="VVR43_001311"
     CDS             14231..14899
                     /locus_tag="VVR43_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009659321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HEU6149672.1"
                     /translation="MTYSQNYLDDILVRMAYHSSGIEGNTISLPETVSIILESTLPRN
                     GKSIREFYEIENHKQAFSYLLDSLANHQALTVGLVQDFHALLVDRLQHDRGQFKQVQN
                     AIIGAEFQTASPAETPYLMTQWADNTAYRLEHAQNEKEVLEILADTHIQIERIHPFSD
                     GNGRTGRLILMYLAMKYLNAPIIIPKDSRAHYMELLANQNVTGLADLFKKSLDYERIR
                     KKQF"
     gene            complement(15363..15821)
                     /locus_tag="VVR43_001312"
     CDS             complement(15363..15821)
                     /locus_tag="VVR43_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149673.1"
                     /translation="MVTDIEQARKNYMADYTPVDLTDAHKLLELAEKLQNEDISINTY
                     ELYKHPEAREKLFWQIAEATYMLLEDTGELQGATPTDEHLKTFVDYLEEKFNNIIKKL
                     IAGTDVAKLQGFLEAVEKDNPHLTKQQKGQLLKDTVVTELFKLWIKRRSK"
     gene            17244..17549
                     /locus_tag="VVR43_001313"
     CDS             17244..17549
                     /locus_tag="VVR43_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HEU6149674.1"
                     /translation="MEKWENQDKILLDKNKRGKDRNWRGRKLLSLKLADIFKELGYRE
                     TLIERVETCGDTLRFIRREDGSLRLYQAYFCKNKLCPMCNWRRSMKYSYQTILVRLN"
     gene            17654..18214
                     /locus_tag="VVR43_001314"
     CDS             17654..18214
                     /locus_tag="VVR43_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug DMT transporter"
                     /protein_id="HEU6149675.1"
                     /translation="MELQQYDELTFENIKHIDENGVEFWYARDLQKTLEYTEWRNFLL
                     VIDKAKIACDTAKNPIVEHFVDVNKSIPNGYNTTRDIKDFKLTRYACYLIVQNGDPRK
                     EVIALGQTYFALKTRQQELQENFDNLTEEQKRLAIRDEIKHHNKSLSESAESAENATY
                     SLPRATMFNNPEARAFSGFSKSSDLV"
     gene            18650..19816
                     /locus_tag="VVR43_001315"
     CDS             18650..19816
                     /locus_tag="VVR43_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU6149676.1"
                     /translation="MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELK
                     AKALQAQIDFEKDGSTVYKAVEIKTYAELVENWLETYCHTVKKSTLMGTKFKIDKYLL
                     PAFGNYRLDKLTPPIIQKQVNQWAKDYNQLGKGFQEYPLLHSLNKRILKYAVSLQAIP
                     FNPARDVIVPRRKEKEGQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLYKTLLATG
                     LRIRECLALKWSDIDLKNGTLDVNKTLNIIKEITGPKTKSSIRVIDLDNKTVLMLRLY
                     KARQSQIGKEMGLTYEKVFSNSFDKHIDARMLSFRLVKHLERAGCPRFTFHAFRHTHA
                     SILLNAGLPYKEIQTRLGHAKLSMTMDIYSHLSKDNQKNATSFYEKAIEKLKSS"
     gene            19936..21051
                     /gene="ychF"
                     /locus_tag="VVR43_001316"
     CDS             19936..21051
                     /gene="ychF"
                     /locus_tag="VVR43_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU6149677.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            21122..21691
                     /locus_tag="VVR43_001317"
     CDS             21122..21691
                     /locus_tag="VVR43_001317"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU6149678.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDEYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            21692..25201
                     /gene="mfd"
                     /locus_tag="VVR43_001318"
     CDS             21692..25201
                     /gene="mfd"
                     /locus_tag="VVR43_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU6149679.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLMSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKELMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
BASE COUNT         7596 a         4787 c         4557 g         8274 t
ORIGIN      
        1 aggagaatcc atgattcatt tttcaattaa taaaaattta tttctacaag cattaaatac
       61 tactaagaga gctattagtt ctaaaaatgc cattcctatt ttatcaacag taaaaattga
      121 cgtgaccaat gaaggtatta ctttaattgg ttcaaatggt caaatttcaa ttgaaaattt
      181 tatttctcaa aaaaatgaag atgctggttt gttaattact tctttaggtt cgatccttct
      241 tgaagcttct ttctttatca atgtagtatc tagtttacct gatgtgactc ttgattttaa
      301 agaaattgaa caaaatcaaa ttgttttaac cagtggcaaa tcagaaatta ccctaaaagg
      361 aaaagatagc gaacaatatc cacgaatcca agaaatttca gcaagcactc ctttaatact
      421 tgaaacaaaa ttactcaaga aaattattaa tgaaacagcc tttgctgcaa gtacacaaga
      481 gagtcgtccg attttaacag gtgtccactt cgtattgagt caacacaaag agttaaaaac
      541 agttgcaaca gactctcatc gcctaagcca gaaaaaattg actcttgaaa aaaatagtga
      601 tgattttgat gtcgtaattc ctagccgttc tctacgcgaa ttttcagcgg tatttacaga
      661 tgatatcgaa actgtagaga ttttctttgc caataaccaa atcctcttta gaagcgaaaa
      721 tattagcttc tatactcgtc tcctagaagg aaactatcct gatacagatc gcttgattcc
      781 aacagacttt aacactacta ttacttttaa tgtggtaaac ttacgccagt caatggagcg
      841 tgcccgtctt ttatcaagtg cgactcaaaa tggtactgtg aaacttgaaa ttaaggatgg
      901 ggttgttagc gcccatgttc actctccaga agttggtaaa gtaaacgaag aaatcgatac
      961 tgatcaggtt actggtgaag atttgaccat tagtttcaac ccaacttact tgattgattc
     1021 tcttaaagct ttaaatagcg aaaaggtgac cattagcttt atctcagctg ttcgtccatt
     1081 tactcttgtg ccagcagata ctgacgaaga cttcatgcag ctcattacac cagttcgtac
     1141 aaattaagtg aaagaggttg agcctggctc gcctctttta tgatataatc gaaaaagaaa
     1201 aggagagtag tatgtatcaa gttggaaatt ttgttgagat gaaaaaatca cacgcttgta
     1261 caatcaagtc gactggtaaa aaggctaatc gttgggaaat tacacgtgta ggagcagata
     1321 tcaaaataaa atgcagtaat tgtgagcatg ttgtcatgat ggggcgatat gattttgagc
     1381 gaaaaatgaa taaaattatt gactgagaac ccttagttag agggttagca ctttatccct
     1441 ttttgtgtta gattgtaatc tacacgcttt taaacttgtt tatagcgcct aaacccttga
     1501 tattactgac tttttgaaaa atctcatttg attagaaatc attaaaagtt cttaaaaatt
     1561 ctcaaaaagt ccacaaaaaa agcctcacaa aagtccccct gattcgtttc taagggcttc
     1621 tagtttatcc atggtgtttt aatcgtccgg tacaaaacca agcaaaatag ggaggcgaat
     1681 atgaagccta gggcacccta tacacattag tctctgtggt aaggttaaat caatctgcat
     1741 gtaccagacc agctaagtgt tctatggctt tttgccttat aaggtatact gtagtctttg
     1801 acctatctat ttcttcagca acctgccaag cttcgagaac attcaagtag aacagcctga
     1861 gaacagaacg ctcaagcgga ttggccagct tatcgatcag cctagatatt tccattctct
     1921 cctcagtaag tcgctcaatc ctctgaagcg tatcctcttt tagcttcaga acacttataa
     1981 gattattctc tgccgtattt accctgcttg tttgtactct ggtattgctt agttcttgct
     2041 ttttgataat accactttct aaagttgcaa gctctaaata taagccttct atctctttgt
     2101 ttatccactt aacgccctct agtgtttctt ttacctgctc tggtgtcatg tctcggcctc
     2161 ctgtatgata taatagtctt tgtgagaact attagctgag acagagagtg tcttggcttt
     2221 tttcgttttc tctatgttcg ctctagcttc aaatgcttcc ccgtgagaaa aaatgtacaa
     2281 tgacggtgta aagctcatag aagtgcgtgg ggagggagat agcccccgta tctccttgtg
     2341 gtttgataag caattaaggg atgtttttat ctctcttatt tccttgtcat tctgcaagga
     2401 attaaggcaa gttatttctt tgcttatctg cttatcattt ggtaagcaac aaatccaaaa
     2461 ataacagact tttaaattgc tcttatctcc ttatcatttg gtaggaaaat aaggggagtt
     2521 attttagttc ttatttcctt atcgtttgac aaggagaaaa acgaaaataa ggagctttta
     2581 aattcgtctt aaccccctat cgttttgtaa gcaattaaga aggcttattg tcgtccttat
     2641 ctgcttgtca ttctgcaagg agtagaaccg aaataagagg gctaaaaact tcgcttatct
     2701 gcttgtcgtt tctcaaggag ttaaggaggg ttattatttc tcttatctgc ttgataaatg
     2761 ataagctcta attatcctcc aataaagcca aattgtccca gaatatccgc aatccttttg
     2821 tatttttaat ttctgaaata gctttttctg cttcttcttt tgtcggatag acttctataa
     2881 tatctttggg attttttcca cctatcctat atcttacctc aaaatgtcca gtatcaatct
     2941 gcgtcaaaaa cacggtatca acttcatcaa ccaccgctaa cttattcaac ttatttaaac
     3001 ggtttttaat cgccttcatc tagtatcttc gcctctaata tttctaattg ctccactacc
     3061 tcaaccattt caaccgcctt ataagccatg tttagaatgc tttgggcgct ttgttgtctc
     3121 gcatacgggc tcactgtctt atcaagcatg atttccctta atacattgac tgcctcaacg
     3181 cttgcattct gtaacagcgt agtagactcc ttaagttgtt cgctacgtct ttcacggtaa
     3241 attctcttaa aggttgcatc gttcaagtaa ttgtaagccg tctttctggt gatctcactt
     3301 aattcactag ctttttttac attcccagtc atgagataat tggccataaa tatttctttt
     3361 tttctgctta attctgtcaa atactgttca cctcgcttta ttgctctaat tctgaaaact
     3421 cacttatccc agtcatttcc ctaagttcat ccatacgttt ttttgatttc ttatagtctg
     3481 ctagcttaat atctttaaat ggtgttttaa taaaatcatc catatctatc tttatttcat
     3541 cttgctgaaa agcaaatctt aaacaatcca catataaaga tatacattca tcagttgttg
     3601 catattccgt ctttccagca tactcttcta acttttctag tcttgctttt aaacttctaa
     3661 ccatccccct acctcgtgtg taattctgtc tgatttatgt aaaaaaaggg gattgctccc
     3721 ctgtgtttat tgaccagaat aatcagcaag gcctttatat tcgccctcta cgtccaattt
     3781 ttggaatagg ttaatacttt cattacccag catttccaac gtaccaaaag cagtcataga
     3841 gtccataagg ataggcttat cagaaagcaa gcgttcagca tagtctaata gtttcagctc
     3901 gtagtctgtg accttattca gcaagctctc aaagtcctct gactctttga gttgaagcac
     3961 gcgctcccgt ttataacgtt cttcaaatgc ttcatcgttc actggttgct tgtaatagtc
     4021 tttgaaaccg tcacggatac gtttgaaggt cttgtttagc ttgtgatcct ccacgtactc
     4081 agctactagc gtccctttat tcttgtaagt gattgaaata gacggtacta cataagttcc
     4141 aatcatgtag cccatcaatg cactccctgc cacttgggcg gtgtcttggt ctttaaattc
     4201 gtaagtgaaa ttaaatgttt ttgctttatc tgaaaatgtt tttaatgtca tgttgttttt
     4261 cctctttctg tttttagggt gtcactagta gttacaccat tgcaaggggg tcggtactat
     4321 ctaccccatt ttgtttaaat gttttagtgt ttgtcaggta ctgcttttag ttcatcaagc
     4381 tctttaaaga ctatttcaaa actttcctga atccgttcga tgtttttatt gcttactata
     4441 gcgttatggt tcgcattctc aataaagcca tccagcgcct cactgatccg ctcaacggtt
     4501 tcttctagtc taatcactct ttgacaaatg ttcatcgcca tctggtttgc tccttttttc
     4561 tcttagatta ggttttgatt aggtttaaaa aataaccctt caaaagccta ctatatcaac
     4621 gtttcaaggg tgttagatta gggttagttt tactttttaa gttcgcgcct atataacacg
     4681 tatatatatt attttttata tagagatatt agaaataaaa actaacctac taacctaaat
     4741 actcgcaaag acttttatat caacgtttac aaaggttagt gtttaggtta tgtttctatt
     4801 ttttgcataa cctaaattgc tataaccctt ggtgtaattg gttttttagt attaaatttc
     4861 ctaacctaaa tcttcatctt ctaagtgtat tccccatata cctttaacaa atcttttacg
     4921 ttgaaaacct tgtgggtcaa gtacgtcata aaacttagag ctaaccgttc cgtttttggc
     4981 tgagtactta tatgacgttg ttttttccaa ttcggccatt actgcattgc taaattgtcc
     5041 aagtttaggt ttatctatac ctatatcctc agcaaactct tttaatttat ttcttgcaat
     5101 aaacattgga acatggttta tttcatgcca cccgtttggt atgtagaaat tctctaccca
     5161 aactttgata taatcgttat cgtttttgta cttgctaagc attttttgta ccgcttcagg
     5221 ttctataaag ctatcaaaat ctggcatatt taaaacttta aacaaaaccc actctagcag
     5281 ctctttgttc tttataaatc ggtctttgat ttcatgacgt tctttctgac cgttaaaatc
     5341 tgcacggaaa ggaatgatac aaagccgtct ataccacccc atggtcttat ttctagctct
     5401 aggcaaatca ttgcccgaaa agatacacaa tagtctgaaa cgtgcttcca cgggttgtaa
     5461 gcttttttta ttgacctgca ctggatctcc actaattaca ctcataaggt cagaaacttc
     5521 atccaggtac ttgttagaaa tatcatctcc aatattacaa acctttcctt ccaaagcgcc
     5581 taaatagaac tctttcccaa actggtcagg tttcaaatta ctaatatttg accgtcctat
     5641 taaattctcc agcaaggctt gaaaagtacc ttttccatta ttaccatctc caaccattag
     5701 caccattttc ttacgtgttc ggttgggatt gatagcctca tttatgactt gccacaataa
     5761 agctacaact tctttatcgt taactgctaa agcctctaac catctatcaa aatcaaacca
     5821 accatctaaa ataggctttc tggcgcatgg attgtattcc gtttgtatct tactggtaat
     5881 gacaaaatta ggactaaatt cctctagttt atgagtttta atattataaa ctccattcgc
     5941 tactggaata tatcgataat cgtccagcgg tggtttcatc ttagtttctg tacggatata
     6001 ggagataagt tctaaaaaga acttgttaga agtcaaacgt gagtcatatt ttaaaagcaa
     6061 ttttcggaaa atgtcgttac ttgatacata atggcctaaa tccaaatggt aaagatataa
     6121 cttactaata tcacttataa ccccctcacc tataaaggta aaatggcaaa tttcctgtaa
     6181 cgctttggct acgattgcaa cacttggtcg tgggatttct accctttcgt ttttctttcc
     6241 ttcattgacg atataggagt tttccttacg ccattgatcc ccaagctccc aaatcctact
     6301 ataaagttcc cacatcgttc taggaggttg ttcttgctct ctgacctcca agatttcact
     6361 ttttaggttt gctaattctt ctagttctat ggttctaacc tctctttcta tactcagccc
     6421 gtgcaatact gctaaaagta cggtctagct cctcaatagg caatggttca accgtcacgc
     6481 tattggctat ctttgtcagt tcataagctg tctctaggtc acaatcaacc cacttattaa
     6541 agagtaagcc tacaaatcgt gtcagtgcta cgttgcgccc tccttcgtct ccaaatccgt
     6601 tgaaaagcgt gtcaataatc ctcatagtca ttgacctctg gccacttact ctaggtttat
     6661 aacgctcagt agttccttgc ttcgctcttg gttcaacctt ggggactgga taatcaagtc
     6721 catgctctac aatcttttga taagttgctg ggtcgcctgt tgttactggt agcccttgga
     6781 gttgtgacca ggttaaactg gccatgtcaa agggtagccc aatcttgtca gcaatctctt
     6841 ttactacctg cttataggtt gcctcgttca tcacgttgtt agatttcacc acaaggcgaa
     6901 aacggggctt ttctatgcta tgtttgatag tcgggtataa gatataagag tagccaaaca
     6961 aagcgctaga aacggcttct atgaagtcct cagtcgtccc ctgtatatcg tcataatcaa
     7021 ggaaaatcaa atcccgatag attagactgg tgttgtttcg tttgtaactc ccgtttttct
     7081 ccggcataac cttaccactt aaacaatatg gcgcctgggt tcttttgtat tcctccggat
     7141 cagcactttc agggactacc aaaggcttaa agcgttcaat gtactggaac ggctcaatct
     7201 tatcaaatgg atagacaaga ttactctgga aacctctagc ctcgtaaatt gtcattcatc
     7261 cacccccaga aacttccaga tgtcagttac taaatagtaa atcattcttg aaccatcgtc
     7321 cggcggttga tagcgtctta aaccctgact ttcccactta ttcagcgtgt tgtcactaat
     7381 tttcaattcc tctttgagtt caactctatt tattaacttg gtcaatcttg gcggtacttt
     7441 ctcacgcgct tccaggtatc tttccactac ctccagaatg ccatgcgcta ggtcttgctc
     7501 gctttctcgg cttaggctaa acatatccgc ccacctcctt caaggtttct ttgtagcttt
     7561 ctaggtcgct attcatcaac accgctaggc gcttgctctc ctcctgtact tggttgtaaa
     7621 aagccttagc gccatctagt aactcgcctt tattcgctgg aataaagtac ccactaaaaa
     7681 cgccacatct aacccctaca atagggatgt tgtgcttaac tactagacgc ttgataatgt
     7741 cacgtacagt tctttctgtt agcttggttg tcaggctaat ttctgaccct gttatggagt
     7801 tctcagcccc taccttgatt agtcttaaaa ctcgcttgtc attctctgat agactcatcc
     7861 aacccctcct ctcctttgct tttatttaca aaggttattt gtccgctcgc taccccttgc
     7921 aaaatagctt tttgagtctc tatgattgta tcaagggctt tcaagatagc tgtcttagtt
     7981 tctaaatcca acgcttgttt tgtcaacaag cccatagtta cagctaactt tgttgcattg
     8041 cccatacacg tagctagaaa aatctcttta gtaaaataag gttcatctgg tattttttca
     8101 ctatcaaggt atatcttcac tatgtaactc attccatccc tccccatacg ttgactcctg
     8161 caagctggat atatcgccca tattcagggt ttaaatcctc gctaggtgtt tttatcgtct
     8221 gttggttttc tcgctcaatt tgggcgcttt ttttgcggtc tcggtggttt aaataaagca
     8281 gtaagccaat caaaatcacg attaagacag cagcctgtgt gttacttata tctagttcat
     8341 tcatgttttt cctccaattc tttgcggtac attctgatag tattaactag attttccttt
     8401 gcattgataa gacaatcata agcaaggtta aaaatagcgc tctgtgtgtc gtattccaag
     8461 gttaaaagca tggtcttttc tttggtgctt atgtttttgc tgaaaaagtg aaaagtagcg
     8521 tcaaaagcgt tttcagcggt gttaagtcct aaggttaaat catctagttc gtctaaaata
     8581 tttctaattt cttcttttgt catggttgtt tccttttcaa ctagtcgtcc acctcttcgg
     8641 gtgttacctt tctatctaaa aaatcagtga tgagctgtaa taggtttgga tttcttgcct
     8701 tgatgtcagc cattacttca tcaaattctg cttgtgtcat tttgcctagg tctagtatca
     8761 ttgcattgcc tcctaatcaa tcatcattcc acgagtatat aaggatgaat ctgtccatga
     8821 atccaaaacg ttcttttttc ctcgtttttt ctttgcgata tcaaccgcta tgagttccca
     8881 tacataattc aataattgac tttgttccat tgggtaggta ttttctttag ttatttcagc
     8941 taggtaagtg tttaagaaaa gaaatccatc aaagttggaa agtagcttta taaactgagt
     9001 atcaccccaa aaatttctgt aataagactc ttctcgttct tctagttcac ctattacctc
     9061 agcaatcacc ctctgtttca tcctttctgt ttgttccttt atcgtttgct gttgttcatg
     9121 gtattctgtg ctagttagtt cactgtaaac atcatccaag tcgttcaaca ctctactgat
     9181 ttctctttta gctaatgcag tttcagcccc tacaaggctt ttttgtattt cttctaaatt
     9241 tgttgaaata gcttctaatt tatctgatat catgttttcc tccattggcc ttttaattgt
     9301 cctgataaaa cccatattct agaaaaatcg ttattttcgt cagcttggtg taattccata
     9361 ctaattctat ccaagctttt agcgataata tcgtatgttg tttcttccat acttttacct
     9421 ctgtttctat gtttgtgtaa tcgccttgat ggctttttaa tgcttttttc ctgtcacatg
     9481 cctcatgctc tcggtcgcca aacttctgag cgtggggctt ttttgagttg tttcttatac
     9541 agtttttttc ttgtaagtac tagcctcacg ctcggagtcg ccaaattgaa agcgtgagaa
     9601 agtaccagtt taaagagttg gcgctctatg cttttcaaaa ccttttctaa ttgcttgcct
     9661 gcacttcggt tttcttagtt tttcttcgtt tcgtttacgg ctttatctgc tagccgttgc
     9721 cattgttttc taaattcttg ttcatctatc cgcccatgca gaaagtcgct caggacgtaa
     9781 gttgcacggc tgtaaaatcg cttggctcta tcataatttg tcattctttg cctcacttac
     9841 tgcttttact accttttctc ttagttttgt aaattcttca ataaactcat cttgagatat
     9901 aaccccacga ttaaaagtta taatcaaggc gcttgctctt tttgtgtatt gttccatctg
     9961 ttacccctcc atcatgtcat aaagtagggc gtaatgttta tctgggattc tgtccaaggc
    10021 tttcaagccg tcgtgttctg ctttttgtct ggtttccgcc ttgaccgtac tatcaaaggc
    10081 gatagaaaaa gcattcagca ttgccttgta gcggtctacg ctcttcaaat agcgcccacg
    10141 ttctgacaat tctttatctt ccaattcctc ttttaccgta ccgtccaaga gtgcgaactt
    10201 gctataaact cctttttcta gtgtaaaatc taggcgattg ttttgtttca gcttgcagag
    10261 gttggttctg caactctcta ggttacggta acctaatact ttagtaattt cttctagacg
    10321 cttaccctct aattctggca atttttcagc tatatcttta aattttacta cttgatgttt
    10381 ctttctcatt ctttacctca tttttgggta cgcaaaaagc gcactctatt tctatgtttg
    10441 acaaataaga gtacgcatga taagatattt acgtacctca ttcgtgggga cggatacttt
    10501 gcaacttctc ggattggcgt ttgacaagtt gcaaggtatt ttttatttag taagattttc
    10561 aaaggctttt ctcaaggttt caggttttgt caaaccattc tttttaccgt actcttccag
    10621 cttactattt agctgttcgc taactctgac tgttaatttt acggtattag agttttctcc
    10681 cttcggacgt cctactttct ttattttgtc agtcatcgga ttgcctcctt tcttgacgac
    10741 ataaattatt ataattattg tcgtcttaaa tgtcaacccc taaaccgaaa aaaatttaaa
    10801 atcttcccag cgtaccttat tttattttca atgtactagc ggaaaccgct gtattatgct
    10861 ataatctagg tatagaaaaa tatctatacc cttgatccag tcgcttgctt cagtcgccaa
    10921 acgttcagca agtgactttt ttttattgtc tttttcatgc tttcttccct gtctgggggc
    10981 tataaagcaa atctttactt tcgataagtt ccagaatcca gctgaatccc tgctccaccg
    11041 tttcaagaaa tgcacctagg tcttcactgt ccaataactc gtagttcata caaagatatt
    11101 cggctagttg tctgtccatc tcaactagct ttttaaaatc cttgaaatac ttaggaattt
    11161 ctactccctt ggcatttgta actgtcttaa attcattttc cattttctat actcctatac
    11221 tttaaaaatt agttctttaa tttctgaata tctcatattc aagttgatca tcgctattgc
    11281 catatcttcc aagcgctgat agtttgtcag ttccgcactt gttaaactgt caataccgtt
    11341 ttcactttct cgctcttgca tgagttgggc tttgtttttc ccagtcgctc cctttagcag
    11401 taggtttgta agagtgctat aggcatgctg aggtgctttc tcccatgatt tgatagcttc
    11461 ggttaaggtc ttgcgctttg gcttttccag ttcccgttga agatagcgtt tagaaagttc
    11521 atcacgcatt tcaaaaaagg ctttaaccag gttcattttg aatttacgaa ctggttctgt
    11581 atttcgtaag taagtgatta acaaagtagc ttgttgctcg ttcaagcgat agattttcat
    11641 tggtcgccct cggccgtcta atttacgcat ttcaaatgcg ataattccgt agctttcaaa
    11701 atcagcttta tgcttcctta aaagttcttg tattgtgtga tgagtgactc cagcacattc
    11761 agcgatgatc tcactcgtag tatacggctc tttcttgccg tccatgtaaa ccagttccat
    11821 gtttttgctc cttattgtta atcaaattcc taaaaactcc gccacctctt tagcagtaaa
    11881 aactccattt gggcttggtt caatatcatc ttccaatact ttaaaatgta agaatgtttt
    11941 tgtctcgtag ctttcgcctt tttcgtaaag tgctttaata cggtcaaata gttttgtcaa
    12001 tgcaacgtca ctggtgtact caacaatgat ttcaccgtgt ccattgtaag ttgtttcttc
    12061 aacgtctgtg atcatacgaa tttcttcgcc taatgctcta gcgataccgt ggtcagttgt
    12121 ttgtgcttga tatacttgtt tattgttcat gttgttttct cctttatgtt ctaggtcgga
    12181 tatttcttcc gagaaggtca atccccagtg gtaaagcacc agtggagtat cttgtagatg
    12241 taatatagta ttgcgattgg gttactcctt tctatatccg tttaaatcgg atattagctt
    12301 aaaaaaataa tgtcgtcata agcaacaccg aaaagttttt caatctcttt tacttgggca
    12361 acatcaggaa aactttttcc attttcccac ttactccaag tagttgtaga aattcctaat
    12421 ttttgtgcta cctctgattg tttcatgttg ctattagccc gcaacgcttt caatgtaaga
    12481 cgcaaatagc cctcactcct ttcttttgga tatccgttta aatcggatac aatgacagta
    12541 tacggtaaaa ccgataactt gtcaacactt tttttgattt tattttcttt ttttttgttt
    12601 cccttgcttt ttctacgttt taaccgtata attaaattat gaattataga aaggcggttg
    12661 cactatgtca ttaggaaata agcaaataat ggcggacaat atcaaaagac ttttaagtgc
    12721 aaaaggttta aaccctcgtc aattagctat tgcattagat tttaagtata caaccgtcaa
    12781 cgattgggta aatgctaaaa cttacccacg tatagataaa atcgaaatgc tggctaattt
    12841 tttcaacgtt tcaaagtctg acttagtaga aaataaaaac gcagaaacac ctaccacttc
    12901 cctcatccaa tccatctatg accaactcac tccaccaaga caagccaaag ccttgactta
    12961 tcttaaaaag cagctgctgg agcagaaaaa cgaaaacata gtatcagaaa acattatcag
    13021 tctggacgac tatagggaaa gcaagacgct ccctgttatc ggagttgtaa ccgccggaaa
    13081 cgggataacc caagacgata acctaaacat agaaaaatgc ttttatactg atgaaatacc
    13141 agacgactat gacgctatcg cttatgtcgt cggcaactcc atggagccaa agataaagaa
    13201 tggcgactac ctatttatca agaatacacc tcaagttgac tataacacta tcggtatctt
    13261 ccaagtagac ggcgctaact acgtcaagaa actgcgtcaa gggtatttag aaagccttaa
    13321 ccctgattgt gctgatattc aactagacga aagcaacgat atacgcacca tcggcgaagt
    13381 cgtgggcatt tatagagaaa agtaaaaaag gagtaaaaaa attatgaaat tttgtcctga
    13441 atgcggaaat tctgttgtcg gttgcaagtt ttgtccgaat tgcggatact caatcaatgc
    13501 ctcgcttaaa acaactcccc aaaaagtagc aactccatcg tctagacctt ctactgtaag
    13561 aagtaaacgt actgataaag tcggacctct tgaaatagac aaaaatcatc gtacatatag
    13621 aatacacgga gcaagaaaag caaaaggttc atcaggtctg attggcggaa ctgctaaagt
    13681 tgttggaaaa actaccttag cgcttgggac aggcggtttg tctttgattc catctttaat
    13741 taaaaaagat aaaaatgata ccgactggta ctccttcgat gatttagtat cttacgaatt
    13801 agttataaac gatcagtctg ttgtttccgg cggtgttgga caagctttag tagctggggc
    13861 ggtatttggt gtaataggag ccgtagctgg cggaatcgtc gctaaaagaa aagcaactac
    13921 caagattttg aatatgacaa tccgaataac atctaacgat tttactaaac cagttgtttt
    13981 tatagattta attaaaaaac ctgttaaaaa cacatctaaa gaatacaaag aagctattga
    14041 aaatgctcaa aagattattg gagctttaga tgttattacc cataattcat aaacaaaaat
    14101 ataccacctc atcgaatacc cccttttttc atggtctatt gtgcaaaaac ggggaaaatt
    14161 gaagaataga aagccgattt acagactaaa gcgtaaaatt gggcaaaagt gacaaataga
    14221 aaggagaatt atgacctact cacaaaacta tctggacgat atactagtac gcatggccta
    14281 ccattctagc ggtattgaag ggaatactat ctctctaccc gaaaccgtca gcattatctt
    14341 agaaagcacc ctgccacgca acggcaaaag tattcgtgag ttttatgaga ttgaaaacca
    14401 taaacaggcc ttttcttatc tcttggactc attggcaaac catcaagctc ttactgtggg
    14461 gcttgttcaa gattttcacg ccttattagt ggataggctg caacatgatc gcggacaatt
    14521 taagcaagtt caaaatgcca ttatcggggc ggaatttcaa acggctagcc cagcagaaac
    14581 gccctacttg atgacacaat gggcggataa tactgcttat cgtttggagc atgctcagaa
    14641 tgaaaaagaa gtattagaga ttttagcaga cacccatatc cagattgaac ggattcaccc
    14701 atttagcgat ggtaacggtc gtactggtcg cctgatactt atgtacttgg ctatgaagta
    14761 tctaaacgct cctatcatca tcccaaaaga ctcaagggcg cattatatgg aactcctcgc
    14821 aaaccaaaat gtaacgggac tagctgacct cttcaaaaag tcactggact acgaaagaat
    14881 acgaaaaaaa cagttttaaa acaacaaaaa aaaaagacaa gctagctgct gctgacttgt
    14941 ctaatatcgc ctgaactgaa ataacgggaa agattcaggc gattagtagc atcttgagag
    15001 attggaagca gaaaggtctg gttactgttg agttgggact ctttcaaacc tcttagtcta
    15061 cgctattatt ataccactct tgcatttaaa aagtgactga cggcatttct cacgctcatc
    15121 agtctataat tctctaatga agtataatgc ggtataattt agacgatttt caacacttcg
    15181 gcattttaga aacgcttaaa gcgctctaaa caatatcaaa aaaaataaaa ctcttgaaat
    15241 attggggctt gtatgctaga atgaaagcat aaagggaaaa acagtgcttc tagcatatgt
    15301 aactaaaaag ccccaccgtt acagcgatgg ggttttttgc tgccctctta aagggttaaa
    15361 tgctacttgc tacgtctctt tatccatagc ttgaaaagct cagttactac cgtatctttt
    15421 agtagttgcc ctttctgttg ttttgttaga tgcgggttgt ctttctctac agcctctaaa
    15481 aagccttgta gttttgctac gtccgtgcct gctatcaatt tctttatgat gttgttaaac
    15541 ttctcttcta ggtagtccac aaatgttttt agatgttcat ctgtcggcgt tgcgccttga
    15601 agttctcctg tatcttctaa tagcatgtaa gtagcttcag caatctgcca aaataatttc
    15661 tctcttgctt ctggatgttt gtataactcg taagtgttga tacttatatc ctcgttttgt
    15721 agcttttcag ctagttctag tagtttgtgt gcgtctgtaa ggtctactgg cgtatagtct
    15781 gccatgtagt tctttcttgc ttgttcaatg tctgttacca tgcttacctc tcttgagtgc
    15841 ctctaaagaa aaagtgatgc ccgtttccgc cttttctttt tactggtttt attatagcat
    15901 acccccactt tttaaaagag tgggggggtg ctctttaata gtcttaatag ttttaatagt
    15961 tttaatagta ttgaaaattt tgacccctta gaaaagcagt aatatcaagg gtttacaagt
    16021 tcgctacctc gacgattacc cccctttttt gtaccttttt agtataaatt tgtagtaatt
    16081 ctttttaaaa aatcggacta aaattaaagg aacttaatat ttcttgtaag gttgttggaa
    16141 taaatagtat aaaagatatg aacgagtata aagagattat ggaaaatgtt aatcaagcaa
    16201 aagaggaatt aaagagaata gatgaattaa tagccgtcag gagctccaga attgattttt
    16261 tagaggataa aacccttaga attacaggaa accaaagatg agcttaaaaa cgaaatggag
    16321 agcctaaaaa gagatttatc tttttttaga aacgaaaata ctcgactgaa aaatgtagtt
    16381 tcagattgta tcaaggtagt atttttgggg tatttttagt agaaagtata ttgtaatttc
    16441 tgagcgattt atgccgtgaa agctacttga ccgtaagcta gatcaaagta cgctagtcag
    16501 ggacgagccg aaaggctgta gcgtttcgga gcggcacgga caaagtacgt cgacctaggt
    16561 tacttgcggt caagtagacc atggaataaa acaagcgggt atgatataaa aaagttatcg
    16621 gcaaaccgaa atatagactt gtttttttgt ttataaaaat gtattattat attgagaata
    16681 agattgttta atttatttag agaggagtgt aagttgatca gtaaatgatt ttaattctgc
    16741 ctttaaataa caaggagttt gttatgaata aagcttggtt attttggagt gtcatagtct
    16801 tatatttttt tataaagttt tttgataaag ttttagatat aaagcttttt ggttctattc
    16861 aaatatggct agataatctc cctattccga tgaaaatact gttaacaata gcattagttt
    16921 tgtttttatt cattgtattt ccatatagag gaaaacggta aaaacggtaa ttagatatat
    16981 aaaaggagct gaaagctccg taaaaaacct actcgaagag taggtttttt cttatcttga
    17041 tactagtagg aaataactct catgctattt ttagggtttc gacagggtct aaacccttga
    17101 tactactgac tttttaggta aaaaaatgcc cttgactttt ttcaacggat cttttataat
    17161 ttagttgttc agaaaaaatt ataaaaagag aaaaaaggca aaggtatttt tgtatttctt
    17221 tgtaattaca ggtaaattat aacatggaga agtgggaaaa tcaagataaa attcttttag
    17281 ataaaaataa aagaggcaag gatagaaact ggcgaggacg aaaattatta agtttgaaat
    17341 tggcagatat ttttaaagag ttaggttata gggaaacctt gatagaacgc gttgagactt
    17401 gtggagatac tcttcgattt attcgtcgag aagatgggag tttgcgttta tatcaagcct
    17461 atttttgtaa gaataaattg tgtcctatgt gtaattggag acggtcaatg aaatattctt
    17521 atcaaacaat cttagtcaga ttgaactaga aatcacccat cacaaacaag cccatataag
    17581 tcccatatct actagttttg ttgatgtcaa caaatgtcaa ccacttacaa tattttagaa
    17641 aggatacttt attatggaac tccaacagta cgatgaatta acttttgaaa atatcaaaca
    17701 catagacgaa aatggagtag aattttggta cgctcgggac ttacaaaaga cccttgagta
    17761 tacagaatgg agaaactttc ttctagtaat tgataaggca aagatagctt gcgataccgc
    17821 taaaaacccc attgtagagc attttgttga cgtcaacaag tcaattccaa acggttataa
    17881 cacaacaaga gatatcaaag attttaaact tacccgttac gcttgttacc ttattgtcca
    17941 aaatggtgac ccacgaaaag aagttatagc acttggccaa acctatttcg cgttgaaaac
    18001 tcgtcaacaa gagctacaag aaaactttga caatcttacc gaagaacaga aacgccttgc
    18061 tatccgtgac gaaattaaac atcacaataa atcattatct gagtctgccg aaagtgccga
    18121 aaatgcgacc tatagcctac cacgcgccac aatgttcaac aatcctgaag cgcgtgcttt
    18181 ctcgggcttc agcaagtcct ctgaccttgt ctaaaccctt ctccttttta gggtgttaga
    18241 aatgttagtt ttccaaccat taagaactaa tagaaacggg attggaattg tttaccccat
    18301 cgctttttag ggactcagaa aatgaagaaa attgtttttt tccagtattc ttgaaaatcc
    18361 gactttttcc aacatttatg tgaagactcc gaaaaaagcg tggttgccaa gacctaaaaa
    18421 acaaacaaaa gaaacttaaa aagcaaccgg ataataacca actttcactc tttgatgata
    18481 tgtaaaaacg ctcatacaaa ccccatatcc gccttatttc ctattctggt attatttacc
    18541 gcctggctaa ttaaaatcga aaataggggt attctcgtag cccctcgcat ggtataaact
    18601 caaaaccttt tctaattgct tgcctgctga tggaaaaagg agtaaaacca tgaaaataac
    18661 agaatacacc aaaaaagacg ggtctacagt ctatcgctct agcgtctacc ttggtatcga
    18721 taccgtaaca ggtaagaaag tcaagacgac tatatcaggg cgaaccaaga gagaactcaa
    18781 agccaaagcg ctacaggctc aaatcgactt tgaaaaagac gggtctacag tatataaagc
    18841 agttgagata aagacttacg ccgaactggt ggagaattgg ctagaaacgt actgccatac
    18901 ggttaaaaaa tcgaccttaa tgggtaccaa attcaaaata gataaatatc tacttccagc
    18961 tttcggaaat tataggctgg ataaactgac gcccccaatc attcaaaagc aagtcaatca
    19021 atgggcaaaa gactataatc aactaggcaa agggtttcaa gagtatcctc tccttcactc
    19081 gctaaacaaa cgcatactta aatatgccgt atctttgcaa gctatcccct ttaaccctgc
    19141 ccgtgatgtt atcgtgccac gtcgtaagga aaaagaaggg caaaaactga aatatctgga
    19201 tgatgataac ttaaaaaaat tcttgactta cctggagcag ctgccaaaca cttacaaaaa
    19261 tttctacgat acggtgctat ataagacgct tttagcgact ggtttgcgta ttcgtgagtg
    19321 tttagccctc aaatggtctg atattgacct aaaaaacggc acactagacg taaataaaac
    19381 gttaaatatt atcaaagaaa tcactggccc taagactaaa tcaagtatta gggtaattga
    19441 cttggataat aagacggtgc tcatgctacg gctctataaa gcaagacaat cccaaatagg
    19501 gaaagaaatg gggttgacct atgagaaagt attctctaat agctttgata agcatataga
    19561 cgctagaatg cttagtttca ggttagtaaa acatttggaa cgtgctggat gccctcgttt
    19621 tacgttccac gccttccgcc acactcatgc tagtatcttg ctcaatgctg gactacctta
    19681 caaagagata caaacacggc tcggtcatgc aaaactttct atgaccatgg atatttatag
    19741 ccacctatcc aaagacaatc agaaaaatgc tacttcattt tatgaaaaag ctattgaaaa
    19801 attaaaaagt tcctaaaaaa gtccataaaa ttattatttc agttatggga aatagctata
    19861 tcaaggaatt ttagcaagtt tacccttttt gtgttataat attagggatt gaaatgaaaa
    19921 cggagaatga gaaatatggc tttgacagca ggtatcgttg gtttgccaaa cgttggtaaa
    19981 tcaacactat ttaatgcaat tacaaaagca ggagcagagg cagcaaacta cccatttgcg
    20041 actattgatc caaatgttgg aatggtggaa gttccagatg aacgcctaca aaaactaact
    20101 gaaatgataa ctcctaaaaa gacagttccc acaacatttg aatttacgga tattgcaggg
    20161 attgtaaaag gagcttcaaa aggagaaggg ctagggaata aattcttggc caatattcgt
    20221 gaagtagatg cgattgttca cgtagttcgt gcttttgatg atgaaaatgt gatgcgcgag
    20281 caaggacgtg aagacgcctt tgtagatcca cttgcagata ttgatacaat taatctggaa
    20341 ttaattcttg ctgacttaga atcagtgaac aaacgatatg cgcgtgtaga aaagatggca
    20401 cgtacgcaaa aagataaaga atcagtagca gaattcaatg ttcttcaaaa gattaaacca
    20461 gtcctagaag acgggaaatc agctcgtacc attgaattta cagatgagga acaaaaggtt
    20521 gtcaaaggtc ttttcctttt gacgactaaa ccagttcttt atgtagctaa tgtggacgag
    20581 gatgtggttt cagaacctga ctctatcgac tatgtcaaac aaattcgtga atttgcagcg
    20641 acagaaaatg ctgaagtagt cgttatttct gcgcgtgctg aggaagaaat ttctgaattg
    20701 gatgatgaag ataaaaaaga gtttcttgaa gccattggtt tgacagaatc aggtgtagat
    20761 aagttgacgc gtgcagctta ccacttgctt ggattgggaa cttacttcac agctggtgaa
    20821 aaagaagttc gcgcttggac tttcaaacgt ggtatgaagg ctcctcaagc agctggtatt
    20881 atccactcag actttgaaaa aggctttatt cgtgcagtaa ccatgtcata tgaagatcta
    20941 gtgaaatacg gatctgaaaa ggccgtaaaa gaagctggac gcttgcgtga agaaggaaaa
    21001 gaatatatcg ttcaagatgg cgatatcatg gaattccgct ttaatgtcta aaaattaata
    21061 aatggtgtca attaggttgg aaaaaaattc caaccctttt ggcttttgaa aggaaaaata
    21121 aatgaccaaa ttacttgtag gcttgggaaa tccaggggat aaatattttg aaacaaaaca
    21181 caatgttggt tttatgttga ttgatcaact agcgaagaaa cagaatgtca cttttacaca
    21241 cgataagata tttcaagctg acctagcatc ctttttccta aatggagaaa aaatttatct
    21301 ggttaaacca acgaccttta tgaatgaaag tggaaaagca gttcatgctt tattaactta
    21361 ctatggtttg gatattgacg atttacttat catttacgat gatcttgaca tggaagttgg
    21421 gaaaattcgt ttaagagcaa aaggctcagc aggtggtcat aatggtatca agtctattat
    21481 tcaacatata ggaactcagg tctttaaccg tgttaagatt ggaattggaa gacctaaaaa
    21541 tggtatgtca gttgttcatc atgttttgag taagtttgac agggatgagt atatcggtat
    21601 tttacagtct gttgacaaag ttgacgattc tgtaaactac tatttacaag agaaaaattt
    21661 tgagaaaaca atgcagaggt ataacggata aatggtgacc ttattagatt tattctcaga
    21721 aaatgatcag attaaaaaat ggcatcaaaa tttaacagat aagaaaagac aactaatact
    21781 tggtttatca acatctacta aggctcttgc aattgcaagc agtttagaaa aagaagatag
    21841 gattgtgtta ttgatgtcaa cttatggaga agcagaagga cttgttagtg atcttatatc
    21901 tatcttgggt gaggaactcg tctatccatt tttggtagat gatgctccta tggtggagtt
    21961 tttgatgtct tcacaggaaa aaattatttc acgggttgaa gccttgcgtt ttttgactga
    22021 ttcatctaag aaagggattt tagtttgtaa tatcgcagca agtcgattga ttttaccgtc
    22081 tcccaatgca ttcaaagata gtattgtaaa aatctcagtt ggtgaagaat atgatcaaca
    22141 cgcgtttatc catcagttaa aggaaaatgg ctatcgaaaa gttactcaag tacaaactca
    22201 gggcgaattt agtcttcgag gagatatttt agatattttt gaaatatccc agttagaacc
    22261 ttgtcgaatt gagttttttg gtgatgaaat tgatggtatc aggtcatttg aagtagaaac
    22321 acaattatcg aaagaaaata agacagaact cactatcttt ccagctagtg atatgctttt
    22381 gagagaaaag gattatcaac gaggacagtc agctttagaa aaacaaattt caaaaacttt
    22441 atcacctatt ttgaaatcat acctagaaga aattctttca agttttcacc aaaaacaaag
    22501 tcatgcagac tctcggaagt ttttatcttt gtgctatgat aagacatgga ctgtctttga
    22561 ttatattgaa aaagatactc caatattctt tgatgattat caaaaattga tgaatcagta
    22621 tgaagtcttt gaaagagaat tagcgcagta ctttacagaa gaattacaga atagtaaagc
    22681 attttctgat atgcagtatt tttctgatat tgaacaaatc tataaaaaac aaagtccagt
    22741 gacctttttt tctaatcttc aaaagggttt aggaaatctc aaatttgaca aaatttatca
    22801 attcaatcaa tatcctatgc aggaattttt caatcagttt tcttttctaa aagaagaaat
    22861 tgaacgatat aaaaaaatgg attacaccat tattctgcag tctagcaatt caatgggaag
    22921 taaaacattg gaggatatgt tagaggaata tcagattaaa ttggattcta gagataagac
    22981 aaatatctgt aaagaatctg taaacttaat agagggtaat ctcagacatg gttttcattt
    23041 tgtagatgaa aagattttat tgataactga acatgagatt tttcaaaaga aattaaagcg
    23101 tcgttttcga agacaacatg tttcaaatgc agagagatta aaagattaca atgaacttga
    23161 aaaaggggac tatgttgtcc atcatatcca tgggattggt caatatctag gaattgaaac
    23221 cattgaaatc aagggaattc atcgtgatta tgtcagtgtc caataccaaa atggtgatca
    23281 aatttctatt cccgtggaac agattcatct actgtccaaa tatatttcaa gtgatggtaa
    23341 agctccaaaa ctcaataaat taaatgacgg tcattttaaa aaggccaagc aaaaggttaa
    23401 gaaccaggta gaggatatag ctgatgattt aatcaaactc tactctgaac gtagtcagtt
    23461 gaagggtttt gctttctcag ctgatgatga tgatcaagat gcctttgatg atgctttccc
    23521 ttatgttgaa acggatgatc aacttcgtag tattgaggaa atcaagaggg atatgcaggc
    23581 ttctcagcca atggatcgac ttttagttgg ggatgttggt tttggaaaga ctgaagttgc
    23641 tatgcgtgca gcctttaaag cagtcaatga tcacaaacag gttgtcattc tagttccgac
    23701 gacggtttta gcgcaacagc actatacgaa ttttaaggaa cgattccaaa attttgcagt
    23761 taatattgat gtgttgagtc gctttagaag taaaaaagag cagactgcaa cacttgaaaa
    23821 attgaaaaac ggtcaagtcg atattttgat tggaacacat cgtgttttgt caaaagatgt
    23881 tgtgtttgct gatttgggct tgatgattat tgatgaggaa cagcgatttg gtgtcaagca
    23941 taaggaaact ttgaaagaac tgaagaaaca agtggatgtc ctaaccttga ccgctacgcc
    24001 aatccctcgt accctccata tgtctatgct gggaatcaga gatttatctg ttattgaaac
    24061 tccgccgact aatcgctatc ctgttcagac ctatgttttg gaaaagaatg atagtgtcat
    24121 tcgtgatgct gtcttgcgtg aaatggagcg tggaggtcaa gtttattatc tttacaacaa
    24181 agttgacaca attgttcaga aggtttcaga attacaggag ttgattccgg aggcttcgat
    24241 tggatatgtt catggtcgaa tgagtgaagt ccagttggaa aatactctat tagactttat
    24301 tgagggacaa tacgatatct tggtgacgac tactattatt gagacagggg tggacattcc
    24361 aaatgctaat actttattta ttgaaaatgc ggaccatatg ggcttgtcaa ccttatatca
    24421 gttaagagga agagtcggtc gtagtaatcg tattgcttat gcttatctca tgtatcgtcc
    24481 agaaaaatca atcagtgaag tctctgaaaa gagattagaa gcgattaaag gatttacaga
    24541 attgggctct ggctttaaga ttgcaatgcg agatctttcg attcgtggag caggaaatct
    24601 tttaggaaaa tcccagtctg gtttcattga ttctgttggt tttgaattgt attcgcagtt
    24661 attagaggaa gctattgcta aacgaaacgg taatgctaac gctaacacaa gaaccaaagg
    24721 gaatgctgag ttgattttgc aaattgatgc ctatcttcct gatacttata tttctgatca
    24781 acgacataag attgaaattt acaagaaaat tcgtcaaatt gacaaccgtg tcaattatga
    24841 agagttacaa gaggagttga tagaccgttt tggagaatac ccagatgtag tagcctatct
    24901 tttagagatt ggtttggtca aatcatactt ggacaaggtc tttgttcaac gtgtggaaag
    24961 aaaagataat aaaattacaa ttcaatttga aaaagtcact caacgactgt ttttagctca
    25021 agattatttt aaagctttat ccgtaacgaa cttaaaagca ggcatcgctg agaataagga
    25081 attaatggag cttgtatttg atgttcaaaa taagaaagat tatgaaattt tagaaggtct
    25141 gctgattttt ggagaaagtt tattagagat aaaagagtct aaggaagaaa attccatttg
    25201 atatttttct tcta
//
LOCUS       DAVHSY010000025        24957 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.025, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000025 DAVHSY010000000
VERSION     DAVHSY010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24957
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.025"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            1..697
                     /locus_tag="VVR43_001319"
                     /pseudo
     CDS             1..697
                     /locus_tag="VVR43_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(899..3157)
                     /locus_tag="VVR43_001320"
     CDS             complement(899..3157)
                     /locus_tag="VVR43_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU6149680.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(3386..3616)
                     /locus_tag="VVR43_001321"
     CDS             complement(3386..3616)
                     /locus_tag="VVR43_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU6149681.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3806..4489
                     /locus_tag="VVR43_001322"
     CDS             3806..4489
                     /locus_tag="VVR43_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6149682.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRLKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4489..5223
                     /locus_tag="VVR43_001323"
     CDS             4489..5223
                     /locus_tag="VVR43_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6149683.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKVDAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            5377..6234
                     /locus_tag="VVR43_001324"
     CDS             5377..6234
                     /locus_tag="VVR43_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU6149684.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIELEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            6376..7248
                     /locus_tag="VVR43_001325"
     CDS             6376..7248
                     /locus_tag="VVR43_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU6149685.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENILALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERARKDKLV"
     gene            7530..8213
                     /gene="rpiA"
                     /locus_tag="VVR43_001326"
     CDS             7530..8213
                     /gene="rpiA"
                     /locus_tag="VVR43_001326"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU6149686.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            8227..9438
                     /locus_tag="VVR43_001327"
     CDS             8227..9438
                     /locus_tag="VVR43_001327"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU6149687.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9440..9982
                     /locus_tag="VVR43_001328"
     CDS             9440..9982
                     /locus_tag="VVR43_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEU6149688.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLGTFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9998..10807
                     /locus_tag="VVR43_001329"
     CDS             9998..10807
                     /locus_tag="VVR43_001329"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU6149689.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIRFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            11283..11678
                     /locus_tag="VVR43_001330"
     CDS             11283..11678
                     /locus_tag="VVR43_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEU6149690.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            11688..12262
                     /locus_tag="VVR43_001331"
                     /pseudo
     CDS             11688..12262
                     /locus_tag="VVR43_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            12287..12799
                     /locus_tag="VVR43_001332"
     CDS             12287..12799
                     /locus_tag="VVR43_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU6149691.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            13453..14163
                     /gene="deoD"
                     /locus_tag="VVR43_001333"
     CDS             13453..14163
                     /gene="deoD"
                     /locus_tag="VVR43_001333"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU6149692.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(14186..14710)
                     /locus_tag="VVR43_001334"
     CDS             complement(14186..14710)
                     /locus_tag="VVR43_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEU6149693.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14763..14999)
                     /locus_tag="VVR43_001335"
     CDS             complement(14763..14999)
                     /locus_tag="VVR43_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU6149694.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSTKLAK"
     gene            complement(15067..15987)
                     /locus_tag="VVR43_001336"
     CDS             complement(15067..15987)
                     /locus_tag="VVR43_001336"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU6149695.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            16177..16580
                     /locus_tag="VVR43_001337"
                     /pseudo
     CDS             16177..16580
                     /locus_tag="VVR43_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16796..17377
                     /locus_tag="VVR43_001338"
     CDS             16796..17377
                     /locus_tag="VVR43_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6149696.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            17374..18651
                     /locus_tag="VVR43_001339"
     CDS             17374..18651
                     /locus_tag="VVR43_001339"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU6149697.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18669..19331
                     /gene="deoC"
                     /locus_tag="VVR43_001340"
     CDS             18669..19331
                     /gene="deoC"
                     /locus_tag="VVR43_001340"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU6149698.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            19318..19707
                     /locus_tag="VVR43_001341"
     CDS             19318..19707
                     /locus_tag="VVR43_001341"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU6149699.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPILPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19798..20850
                     /locus_tag="VVR43_001342"
     CDS             19798..20850
                     /locus_tag="VVR43_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU6149700.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQDWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20994..22529
                     /locus_tag="VVR43_001343"
     CDS             20994..22529
                     /locus_tag="VVR43_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149701.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            22522..23580
                     /locus_tag="VVR43_001344"
     CDS             22522..23580
                     /locus_tag="VVR43_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6149702.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMDPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            23583..24539
                     /locus_tag="VVR43_001345"
     CDS             23583..24539
                     /locus_tag="VVR43_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6149703.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            24624..24957
                     /locus_tag="VVR43_001346"
                     /pseudo
     CDS             24624..24957
                     /locus_tag="VVR43_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         7319 a         4488 c         5630 g         7520 t
ORIGIN      
        1 gttgatagag atagacttaa aaactatctt actgacaatc cagatgctta tttgactgaa
       61 atagcttctg actttggctg tcatccaact accatccact atgcgctcaa agctatgggc
      121 tacactcgaa aaaaagaacc acacctacta tgaacaagac ccagaaaaag tagccttatt
      181 tcttaagaat tttaatagtt taaagcacct agcacctgtt tagattgacg aaacaggatt
      241 cgatacttat ttttatcgag aatatggtcg ctcattaaaa ggtcagttaa taagaggcaa
      301 agtatctgga agaagatatc agaggatttc tttggttgca ggtctaacca atggtgagtt
      361 aatcgctcca atgacttacg aagagacgat gacgagcgac ttttttgaag cttagtttca
      421 gaagtttttc ttaccaacat taaccacacc atcggttatt attatggata atgtaagatt
      481 ccatagaatg gggaagaatg taagattcca tagaatgggg aagctagaac ttttatgcga
      541 agagtttggg cataaacttt tacctcttcc tccctactcg cctgagtaca atcctattga
      601 gaaaacatgg gctcatatca aaaagcacct caaaaaggta ttaccaagtt gcaatacctt
      661 ttacgaggct cttttgtcct gttcttgttt caattgacta tagcagattg aaatgagaac
      721 aaatcgattg ggaaagtaaa attaatttct ataaatgttt tagcaattgt ttcgtactat
      781 ttcagattca gtctactata tatcataatg gacaaagggc aagctgtcaa gaaattacag
      841 ttattttagt aaaaaaagaa gcagaaaaat ttcattttct actccttttc tataggattt
      901 atttttcttt ttcagaactt ttaacttcag cttttttggc agatttaatc tgaatgtttc
      961 ccttgctagt cataactgct ttgagatctt tttcgcttgg attttcaagg tagtagtcag
     1021 tgattgtgtc ctcaatatag tcttgaatag tccgacgaag tgggcgtgct cccatttttg
     1081 gatcataacc taggtcaacc aacttttcct tgaccttatc agttacatcc aaacgaatgt
     1141 tgttgctaga gaggcgcttg ttaacatctg ctagcatgag ctcgacaatc tgaaggaggt
     1201 tatccttgct gagagcctta aattcgataa tgccatcaaa acggttcata aactctgggc
     1261 taaagaagtt accgagttca ccgaggacag aattggtacg tccttctcta gcagcaccaa
     1321 atccaacgct agcttcggtc tttcctgtac ctgcatttga ggtcatgata atgatggcat
     1381 ccttgaagct aacggtgcgt ccttgcccgt ctgtcaaacg accatcgtcc aagacttgaa
     1441 gaaacatgtg cataacatct gggtgagctt tttccacttc atcgagaagg atgagagaat
     1501 atggattgtg gcgaactttt tcagttaatt gaccagcctc atcatagcca acataacctg
     1561 gaggggcgcc gaccaactta gccacactat gtttttccat gtattcactc atatcaaagc
     1621 gaatcatact atcagcagaa ccaaaaagtt cgatagccag ttgtttggaa agttctgtct
     1681 taccgacacc agttggccca acgaagagga agcttccgat tgggcggtta ggggtaccaa
     1741 gtccgacacg attacggcga atagccttgg caatcttatc gactgcatca tcttggccaa
     1801 taacatgaga cttgagatct tcggctagat ggatgagttg agattgttct ttctctttca
     1861 aatcaccaac agggatattg gttttctgct cgataatgtg ctcaatagtt ttctcgctga
     1921 tgataggagt atcctggtct gtgatctttt tcttttgcat ttccttatac ttggcaatct
     1981 ggtcgcggaa gtaggccgcc ttctcaaaat cttcttctcg tgtagcttga gacttgagat
     2041 tttcagcctc aatcaagcgc tgatcaatta ctttaggatc cacaaaattc aaggtcaagt
     2101 tcatcttaga accagcttca tctaggaggt caatggcctt gtcaggcaag aagcgatctt
     2161 ggatgtagcg attggaaaga gttgcagctg cttcaatcgc agcatctgta tattgaacgt
     2221 ggtggtaatc ttcgtatttc ttttgaatcc ctttgagaat agtgattgtt tcgtccaccg
     2281 ttggttcatc gactttaaca ggctgcatac gacgctcgag ggcagcatcc ttttcaatga
     2341 tacggtattc attgagggta gtagcaccga ctagttgcag ttctccacga gcaagggctg
     2401 gcttgaggat atttcctgcg tccatattac catcactcgc agaaccagca ccaacaattt
     2461 catggatttc atcgataaag aggatgatgt cttcacgttt gcgaatttct tccatgagtt
     2521 tttgcatgcg ttcttcaaat tgtcctcgaa tccccgttcc ttgaactaag ctaaccacat
     2581 ccagacggat gacttgttta ccttggagtt tatgtggcac atcgccatcg acaattttct
     2641 gagctagacc ttcgacaacg gccgtttttc ctacaccagg ttcaccgata aggacaggat
     2701 tattcttggt tctacgattg agaatctcga tgacacggat aatctcatcg tcgcgcccaa
     2761 taacggggtc aatgtctcca cgacgggcaa tttcagttac attaatacca aattcttcca
     2821 gcaggccttt ttcttggcta ggtggcggag tttgagcaga tccacgattt tgggaaccat
     2881 aaccgccgtt tccaccgtaa cctccacctg attgggttgg gggaataggc ggagtattgc
     2941 tagaaggtct gaaattgttt agatcattga agaaatcacc aaagggatcg aagtcacgat
     3001 tgttcagatc cgtcatacct ttgaagaggc tattgttagg atctgttttg ataatcttat
     3061 agcagttttg acagaggtca atttgttttt gttttccatt gagattggtg taaagatgaa
     3121 ttgttgagtc gttaatttta cagttttgac aaagcataca tctacctcat ttctttcttt
     3181 agcctgactt gtttaaaggt caaaaatagt caaattctat actctcatta taacaggatt
     3241 ggggtgtaaa gcaagtaaaa agattgaagc tttgagaagt tgttacaatg aaaatttttg
     3301 tgaatttgga ctataaaaaa atcctatttg tgagacaaaa aggattttac ttagacatgc
     3361 agggacaatc ccaacttgtt ttagattagt agagaagttc gtaaatttcc attgcgatta
     3421 agtcaatgct atcaaacgta tacgtttcgc gatcttctac gtcacgaagg gtaaagattg
     3481 ggccgttttc ttcgtcgtgg ctgtacgcaa cttctgcaac aacaactcct tcgcgttcaa
     3541 aattacgttt taaatttccg ccatcgtttg ccattgcttc aaggcggttg atgattctaa
     3601 ccaaatgtga ttccattttg attctccttc atttcttatc gttactattt taccataaag
     3661 gagggcaact tgactagaaa aaactaagat ttctcgctaa ttctgctagt ttaaagattt
     3721 ttaaataaat tggataaaaa atttaaattt taattcaaaa catgttataa tcatacagta
     3781 ttctatttta gaaagcagtg tgactatgaa tttttctttt ttacctaagt atttacctta
     3841 ttttaactat ggggctgttg tgacgattct tatttctatc tgtgttatct ttttgggaac
     3901 tattttgggt gttgtcttgg cttttgggca acgttcaaag tttaaaccgc ttgtttggtt
     3961 ggccaacttg tacgtttgga ttttccgtgg gacaccgatg atggttcaaa ttatgattgc
     4021 ctttgctctt atgcatatca atgctccgac tattcagatt ggaattttag gtgttgattt
     4081 ttcgcgtctg attccaggga ttttgattat ctctatgaat agtggtgctt atgtttcgga
     4141 gactgttcgt gccggaatca atgcggttcc aaaaggtcag ctagaggcgg cttattcgct
     4201 agggattcgt cttaaaaatg cgatgcgtta tgtgattttg ccacaagcag tcaaaaatat
     4261 cttgccagca ttggggaacg aatttatcac cattatcaag gacagctccc tcttatcagc
     4321 tattggggtc atggagttgt ggaatggggc tacaacagtt tctacaacaa cctatctacc
     4381 tttaacacca cttttatttg cagcatttta ctacttgatt atgacctcta ttctgacagt
     4441 agccttgaaa gcttttgaaa aacatatggg acaaggagat aagaaataat gacagaaacc
     4501 ttgataaaaa ttgaaaattt acataaatct tttggaaaga atgaagtatt gaagggcatc
     4561 aacctcgaga ttaaaagagg agaagttgtc gttatcatcg gtccttcagg gagtgggaaa
     4621 tctaccttgc ttcgctctat gaatttgttg gaggaagcaa ccaaggggaa gcttatcttt
     4681 gagggagtcg atattacgga caagaagaat gacctgtttg ccatgcgtga gaagatgggc
     4741 atggttttcc aacaatttaa cctctttcct aatatgactg tgatggaaaa tattaccttg
     4801 tcacctatca agactaaagg tgaaagcagg gaagttgctg agaagagagc ccaagagctt
     4861 ttggaaaaag ttggtttgcc agataaggta gacgcttatc cacagagtct gtcgggtggg
     4921 cagcaacaac ggattgccat cgcgcgtggg ttggctatgg aaccagatgt tttgctcttt
     4981 gacgaaccaa cttcagcctt ggatcctgaa atggtaggtg aggtattggc tgttatgcaa
     5041 gaccttgcca agtcagggat gactatggtt atcgtaacac atgagatggg atttgcccgt
     5101 gaggtggcag atcgtgttat ctttatggca gacggtgtgg ttgttgaaga tgggacacct
     5161 gagcagattt ttgaacaaac ccaagaacaa cggactaaag atttcttgag taaggtttta
     5221 taatctattt taaaatttca agacaagatt agtgaaaagt tcaaccagag ctttttctta
     5281 tagtttgaaa ctataggata acctaggaaa gaagtgttag agggcactag cagtttttgg
     5341 tataatggaa gatatttgaa agaaaagaga agtgatatga cacagattat tgatgggaaa
     5401 gctttagcgg ccaaattgca ggggcagttg gctgaaaaga ctgcaaaatt aaaggaagaa
     5461 acagctctag tgcctggttt ggtagtgatt ttggttgggg ataatccagc cagccaagtc
     5521 tacgttcgca acaaggagag gtcagctctt gcggctggtt cccgtagcga agtagtgcga
     5581 gttccagaga ccattactca agaggaattg ttagacctga ttgctaaata caatcaggat
     5641 ccagcttggc atgggatttt ggttcagttg ccattaccaa aacacattga tgaagaggcg
     5701 gttctattgg ctattgaccc agaaaaggat gtggatggtt tccatcctct aaatatggga
     5761 cgcctttggt ctggacatcc agtcatgatt ccatcaacac ctgcaggaat tatggaaatg
     5821 tttcatgaat atgggattga attagaaggt aaaaatgcgg ttgtcatcgg tcgttctaat
     5881 atcgttggaa aacccatggc tcagcttctt ttggccaaga atgcaacagt gactttgacc
     5941 cactcacgca cccataatct tgctaaggtg gctgctaaag cagatattct ggtggtcgca
     6001 atcggtcgtg ccaagtttgt gactgctgac tttgtcaaac caggtgcggt agtcattgac
     6061 gttgggatga atcgtgatga aaatggtaag ctctgtgggg atgtggatta tgaggcagtt
     6121 gccccacttg ctagctatat tacgccagtc cctggaggtg tcggccctat gaccattact
     6181 atgctgatgg agcaaactta tcaagcagca cttcggacat tggatagaaa ataagagaaa
     6241 cattcgatta atagagtgta ttttctatag ctatatctaa aatggtagaa atgaatatta
     6301 aattttagat ataagattac aaaaggaggt ctgcgtctcc tttttattgt ataataaaag
     6361 tgagaggaaa aaaggatgaa agtgattaat caaaccttat tagaaaaagt tattattgaa
     6421 cgttctcgtt caagtcataa aggagattat ggtcgtctgc tgctgcttgg tggtacttat
     6481 ccttatggag gtgccatcat catggctgct ttagcagctg taaaaagcgg tgcaggattg
     6541 gtgaccgttg gaacggacag ggaaaatatc ctggctctgc acagccattt acctgagcct
     6601 atggcctttt ctcttcaaga ccagcaattg ttaaaagagc aattggagaa ggcagaagtt
     6661 gtcttgctgg ggcctggttt acgagacgat gcttctggag aaaatctagt aaaacaggtc
     6721 tttgttaatt taagccaaaa tcagattttg attgtagacg gaggtgcctt gaccattctt
     6781 gctaggacaa gtttgtcatt tccctcaagc cagcttatcc taactcctca ccaaaaagaa
     6841 tgggaaaaat tatctggaat tacgattgaa aagcaaaagg aagatgcaac ggctagtgtt
     6901 ctgacttcct tccctcaagg aacaattttg gtggagaaag gcccagctac tcgtatttgg
     6961 gaagttggcc aatctgatta ttaccagtta caggttggtg gtccttatca ggcgactggg
     7021 ggaatgggag atactctggc tgggatgatc gcaggatttg taggccaatt ccgacaggcc
     7081 agtctctacg agcgtgtggc agtagcgacc catcttcatt cagccatagc ccaagaacta
     7141 tctcaagaaa attatgtggt cttaccgacg gaaatcagca ggtatcttcc caaaataatg
     7201 aaaattattt gtcaacaaga gagggcaaga aaagataaac ttgtttaaaa tagacagata
     7261 aatctacttc cttctcttaa tttatgattc ttgaaatgcg cctgctttaa ggctaaacta
     7321 gacgtatcaa agttaagagt ttgtttttgt aactggaaag agatgaacaa atcaaataca
     7381 taaaagataa actcattttt atttgtttgg taaaaataaa atgcatattt ttaaagaaag
     7441 attgatgaaa aatgtagatt tgatgttttt acttgaataa aaagcggttt catagtaaaa
     7501 taagaactga gaatgatgga ggtaaatcgg tggaaaatct gaagaaaatg gcaggtatca
     7561 aggctgctga gttcgtgagc gatggaatgg tcgttggact tggaacaggc tcgactgcct
     7621 attattttgt cgaagaaatc ggtcgtcgta tcaaggaaga aggattgcag attacagctg
     7681 taacaacttc tagtgtgacc actaaacagg cagaaggcct taatatcccg ctcaagtcta
     7741 ttgaccaagt agactttgtc gatgtgacgg ttgatggcgc ggatgaagtg gatagtcagt
     7801 ttaatggaat caaaggcggt ggtggtgccc ttctcatgga aaaggtggtc gcaacaccat
     7861 caaaagaata catttgggtg gtggatgaaa gcaagctggt cgaaaaacta ggtgctttta
     7921 aattgccagt agaagtggtt cagtatggtg cagagcaggt ctttcgtcat tttgaacgag
     7981 ctggctacaa accaagtttc cgtgaaaaag acggccaacg ttttgtgacg gatatgcaga
     8041 attttatcat tgacctcgcc ttggatgtca ttgaaaatcc aattgctttt ggacaagaat
     8101 tggatcatgt cgttggtgtt gtggagcatg gtttattcaa ccaaatggtg gataaggtaa
     8161 tcgttgctgg acgggatgga gttcagattt caacttcaaa aaaaggaaaa tagaaggggg
     8221 cataagatgt ctaaatttaa tcgtattcat ttggtggtac tggattctgt aggaatcggt
     8281 gcagcaccag atgctaataa ctttgtcaat gcaggggttc cagatggagc ttctgacaca
     8341 ctgggacata tttcaaaaac agttggtttg aatgtcccaa acatggctaa aataggtctt
     8401 ggaaatattc ctcgtgaaac tcctcttaag actgtagcag ctgaaagcaa tccaactgga
     8461 tatgcaacaa aattagagga agtatctctt ggtaaggata ctatgactgg acactgggaa
     8521 atcatgggac tcaacattac tgagcctttc gatactttct ggaacggatt cccagaagaa
     8581 atcctgacaa aaatcgaaga attctcagga cgcaaggtta ttcgtgaagc caacaaacct
     8641 tattcaggaa cggctgttat cgatgatttt ggaccacgtc agatggaaac tggagagttg
     8701 attatctata cttcagctga ccctgttttg cagattgctg cccacgaaga cattattcct
     8761 ttggatgaat tgtaccgtat ctgtgaatac gctcgttcga ttacccttga gcgtcctgcc
     8821 cttcttggtc gcatcattgc tcgcccttat gtaggtgaac caggtaactt cactcgtacg
     8881 gcaaaccgtc gtgacttggc tgtatctcca ttttccccaa ctgttttgga taaattgaat
     8941 gaggctggta tcgatactta tgctgtgggt aaaatcaacg atatctttaa cggtgctggt
     9001 atcaaccatg acatgggtca caacaagtca aatagtcatg gaattgatac actattgaag
     9061 actatgggac ttgctgagtt tgaaaaagga ttctcattca caaacctagt tgactttgat
     9121 gccctttacg gccatcgtcg taatgctcac ggttaccgtg attgcttgca tgagtttgat
     9181 gaacgcttac ctgaaattat cgcagctatg agagagaatg accttctctt gattactgcg
     9241 gaccatggaa atgacccaac gtatgcagga acggatcaca ctcgggaata tattccattg
     9301 ttggcatata gccctgcctt taaaggaaat ggtctcattc cagtaggaca ttttgcagat
     9361 atttcagcga ctgttgccga taactttggt gtggaaactg ctatgattgg ggaaagtttc
     9421 ttagataaat tggtataata tgacgcgcta tgctttgctg gtgagaggta tcaatgttgg
     9481 tggtaagaat aaggtcgtca tggcggagct tcgtcaagaa ttgacaaact tgggactgga
     9541 aaaggttgag agctacatca acagtggcaa tattttcttt acttcgatag attccaaagc
     9601 ccaattggtt gaaaagctag ggactttctt tgcagtccat tatccattta ttcagagctt
     9661 ttctttactg agtctagagg actttgaggc ggaacttgaa aatctaccag cttggtggag
     9721 cagagacttg gcacgaaaag attttctctt ttacactgag ggtttggatg tggaccaagt
     9781 catcgcgaca gttgaaagtt tagagctgaa agatgaagtg ctttattttg gaaaacttgg
     9841 gattttctgg gggaaatttt ctgaagaatc ctattctaag actgcctatc agaagtactt
     9901 gctgaaggtg cctttctacc gccacattac tattcgtaat gctaaaacct ttgacaaaat
     9961 tggtcaaatg ctaaaaaaat aataaaggag acacacaatg acatttttaa acaaaatcca
    10021 tgaaactgct actttcctga aagaaaaggg aattgcagcc cctgagttcg gtctaatcct
    10081 tggatcagga cttggagaat tggcagaaga aatcgaaaat ccagttgtag tagactatgc
    10141 tgagattcca aactggggcc gttcaacagt agtcggtcat gctggtaaat tggtatatgg
    10201 tgaactggca ggtcgcaagg tcttggctct tcaaggtcgt ttccatttct atgaagggaa
    10261 tcctctggaa gtggtgactt tcccagttcg tgtgatgaaa gttcttggat gtgaaggtgt
    10321 tattgtaacc aatgcagctg gcggtatcag atttggtcct ggtaccttga tggctatctc
    10381 agaccatatc aacatgacgg ggcaaaatcc attgatgggt gaaaacttgg atgactttgg
    10441 cccacgtttc ccagatatgt ctagggccta cacaccagaa taccgtgcca ctgcccatga
    10501 agtggctaaa aaacttaata tcaagcttga tgaaggtgtc tatatcggag ttactggtcc
    10561 gacttatgaa acaccagcag aaattcgttc ctataagaca ctgggagcag atgcagttgg
    10621 tatgtctacg gttcctgaag ttatcgtggc agcccactct ggcttgaaag ttctgggaat
    10681 ttcatgtatc actaactttg cggctggttt ccaagaagaa ctcaatcacg aagaagttgt
    10741 agaagtgact gaacgtgtta aaggtgattt caaaggcttg cttaaagcga ttcttgctga
    10801 attgtaagaa aaaagattta aaaggggtag tgtctctgtc ttttcaggat tgactgccta
    10861 tccgtattaa agaagaaaca gaggaatact atgagcttct tcctgctctt ataactgaaa
    10921 gaagcggaag aataggtgtg tctgatctga tagccagcat tgtgaaagac aagattctag
    10981 gatactagca ttagcttcct agccaagcag actagtatga taaggagaga tgagaatgaa
    11041 ttgactttct gaatttctca gtcttatcat atatagcaca atgagatttc gcttgagtct
    11101 gcttgtaaat aaacgaaaag aaagataaga aataatgaaa attggtcaac gaattatgcg
    11161 ctttggcata aaaaattaag tatcggagtt gtatctgttg tagtcggctt tgatttctag
    11221 ctccagctgg aatttcagcc aatgaagtaa agcaagatgt aacatctgaa gtggtaatag
    11281 gtgtgctaga ttctaaggag gaattgaaag agtcagaaaa tgatgctcca aaactagaaa
    11341 ctcctcttag agaggagcca agactagctc ctcaaacgct tccggaagca agtgaagttc
    11401 ttgaaaacaa aagggaagag tcaaaagtag agataacaga gccagctcaa gcggatgata
    11461 tccgcaaggt tgttggggaa ttagccaagg atataagtat tactaagttg tatatgacag
    11521 gtcattctct tggaggctac ctagctcaga ttgcagcggt tgaagattac caaaaatatc
    11581 ctgattttta taaccatgta ttgaggaaag tgacaacttt cagtgctcct aaagtgatta
    11641 cttccagaac tgtttgggat gctaagaatg gtttctgaga tgttggtttg gaaagtcgta
    11701 aattagctgt tagtggaaaa attaagcatt atgtggttga taatgacaat gttgtgactc
    11761 ccttgattca taataatcgt gatattgtta catttacagg taattcacgc tttaaacacc
    11821 gttctcgtgg ctattttgaa agtccaatga atgatattcc taactttaat attggtaaac
    11881 aagctacctt ggataaacat ggttatcgtg atccgaaatt ggataaagcg cgattcttta
    11941 agaaacaggc tctacctcaa tcttctagtc aaccaagcgc tgaaccaatg gaaaatattg
    12001 ccttaggaaa acaggttact caaagttcga cagctttcgg aggaatgcta gaagagctgt
    12061 ggatggcaaa gtcgatggta actatggtca caattctgtc actcatacaa acttccaatc
    12121 taagccttgg tggcaagtag atttggctaa agaagaaacc attcgccaaa tcaatattta
    12181 caaccgaaca gacactgccc aggatagatt ggcaaacttt gatgtcattc ttttagacgg
    12241 ttctggtaaa gaaattgagt gaaaacgtat aatatctcct aaagatgtgt cagcacaaat
    12301 tacgattaac cataaaaaag cgcgctatgt tcggattgag ctagaaggct ataatgccct
    12361 cagtcttgca gaagttgaag ttttccgctt tatagctacg aatggtgaaa cggcgataca
    12421 agtttctaag tcagttcaac caatcagtca gactcctgtg aaagataaaa cattgacaat
    12481 tcaacacagt ggagcttaca ttgcccgcta ctccataact tgggaagaag ttacagtaga
    12541 taaagatgga aaccaagttg ttcgtagtca ttcttgggaa ggaaacggtc gcaaccagac
    12601 tgcaggtttt gtcctcaacc tcccaatcaa agaaaatatg agaaatctgc gagttaagat
    12661 tgagaaaaag acgggcctac tatggaatag atggcaaaca atctatgaaa acagaccaat
    12721 tttagctcaa ccccaccgta aaattaccca ttggggtacg acattgaatt ccaaggtgag
    12781 tgacgatgat gtcttgtaat ctgatggtac aatgacagtt agtttgtcta gtttataaga
    12841 aagtactacc tgagcttgaa tagaactcag gtagctctct gtgaaagaac aaaattaata
    12901 ctcaatgaaa atcaaagagc aaactaagaa actagccgca ggttgctcaa agcactgctt
    12961 tgaggttgta gataagactg acgaagtcag tcacatatat aatccaaggc gacgttgacg
    13021 tggtttgaag agattttcga agagtataaa cagaaaggta gagcgcgtgt tctaatttga
    13081 acacgagtag aaaacttttc taaaaacaaa aacgaaagga tgggtaaact gtattcgctg
    13141 aactgaatac gggcgactct cctctaaatc aaaattaaga aaggaattga ccccacccta
    13201 aaagtagtgg gaaaaagata gttggtctag cgagcatcgc tcactgcgcc caactcctat
    13261 tttcccttcg ctttttgatg ggtttggtat ctttctcaat ataaaatata aaataaagaa
    13321 aggtagagcg tgtgttttga tttgaacacg agcggaaaac tcggaaaata gataatctga
    13381 ctgaaaaatc aggatttctc gtcaggttcc taattttcag tcgttttctt ctcgctcttt
    13441 gtatcataaa ttatgtctat ccatattgct gctcagcagg gtgaaattgc tgataaaatt
    13501 cttcttcctg gggatcctct tcgtgctaag tttattgcgg agaatttcct tggtgatgct
    13561 gtttgtttta acgaagtgcg taacatgttt ggttacactg gtacttacaa gggtcaccgt
    13621 gtatctgtca tgggaactgg gatgggaatg ccatctattt cgatttatgc gcgtgagtta
    13681 atcgtagact acggtgtgaa gaaattgatt cgtgtgggaa ctgcaggttc tttgaatgaa
    13741 gaggttcatg ttcgtgaatt agttttggcg caggcggctg caaccaactc aaacatcgtt
    13801 cgtaatgact ggccacagta cgattttcca caaattgcta gctttgattt gcttgataaa
    13861 gcctaccata tcgccaaaga acttggtatg actactcacg ttgggaacgt tttgtcatct
    13921 gatgtctttt actcaaatta ctttgaaaag aatatcgagc ttggtaaatg gggagtcaag
    13981 gctgtggaaa tggaagcagc agctctttac tatcttgctg cccaatacca tgttgatgcg
    14041 ctagctatca tgaccatctc tgatagcttg gtcaatccag acgaagacac aactgcagaa
    14101 gaacgtcaaa ataccttcac tgatatgatg aaggttggtt tggaaacctt gattgcagaa
    14161 taattatagc caaaaaggaa gccctttatg aattgtagga cttccttttc ttatccagaa
    14221 attgatctag ctctctctga tttcgaagaa tagtgacttt atgtgaatat tcttggcaaa
    14281 gtttttggta attttctttt tgagttttgc tacgcccatc ccaaagaatc catctgataa
    14341 actcccagtc aaagcgttca gggcaatctg ccgccatact ttctctgact tttccacggt
    14401 atttaagata acgcttaaag gctctaaaga gacaggtcaa tggcaaaaaa ttgagaaaga
    14461 tgatttggtc agcttcttgc attcgttctt ggtagtagca ccaagaataa ttaccatcga
    14521 tgacccaagc tttatgcttg gtgagaaagt tttttatctc ggttaacatc cattcgcagt
    14581 cactgtcttg ccaaccaggt tgaaattgga gtgtgtccat gtgcagtttt ggaatggagt
    14641 agtagttaga taacttttct gctagagttg acttaccaga accagaatat ccgataattg
    14701 tgattttcat tttctacctt ttcctatttg gagacaaaaa aacagcctct atggactgtt
    14761 tcttatttag caagtttagt tgaaagacga gctttatcgc ggcttgcttt gtttttgtga
    14821 atcaaacctt tagtttctgc tttatcgata gctgagctag cagcacggaa aagttcttca
    14881 gatgggtttg cttcgaaagc ttttatagca gtacgcatag ctgatttttg agctgagttc
    14941 ttttcgtttt gtttaacgtt caattcagcg cgtttgatag ctgatttaat gtttgccaat
    15001 gttcttacct ccatatttac taactatacc attatatatg aaaacttacg ttttgacaag
    15061 ggaaaattac ttttttaagt aaatttcatc gatttcatgg ttcttgcttt tatgaagaat
    15121 cacttctgca cgatttctgg ttggttcaat ataattttgc agatttgtga gattgatact
    15181 gatccagacc tgatgggcaa aggactccac ttccccaatc ggcatctgag taaaacgata
    15241 atagtagcta tcagggtcgt tttgggctag gctcagcatt ttcaagaaac ggtccagata
    15301 ccaactttca atatcatcca ctccagcatc tacatagatg gaaaagtcaa agaagtcagt
    15361 gatatagaga cgatcgtttt gtggattttg aaagacatta attccctcaa caattacaaa
    15421 atcagcagct ttgacacttt gtttcttttc gggtacgatg tcgtaaactt catgagaata
    15481 gacaggaata tctacatctt gtccattttt gatgcggtcc aagaagttga gaagagcttc
    15541 catatcatag ctttcaggaa atcctttacg atttaaaatc ccctgctcaa tcaaggtttg
    15601 attgggatat agaaaaccat cagttgtaac caactcaacc gtagcatctg taaacgtacg
    15661 ggacagtagg atttgaagta ggcgactggt tgtggatttt ccaacggcaa cactcccaga
    15721 aaccccaata ataaaaggtt gagatttact ttcacgttgg aggaaaattc cttttgaaaa
    15781 ggctaaatct tccttagttc gcttgtaaat ctgaatcaga tgagccaagg ggagatagat
    15841 atctgtaacg tcttggagac tgatttggtc attaaaactc ttgatagatt ccaattcttc
    15901 ttctgtcaaa ggaggtgttg tctttcgatg taaagattgc caagtctggc ggctgatttt
    15961 ttcaaaatgt aaaaattcgt tggtcatttg ttttccccta gatattttgt ctatcatacc
    16021 ataaaaagct aaaaaaataa agcggtttct tgaatgtggt aagtcaatgg tatatagtat
    16081 aagtgatcaa tttattgatg aaataggaga tagattctac tgatttataa gcttataaag
    16141 ggggcttttt agttcacaac ttataggagg tgtactatga aaatcttaaa acgttacata
    16201 ttggaactct gttttatttt aagttttgct ttacctttta taaaaggaac caatgcagat
    16261 aatggtagat gctttgtgga aacctattac ggttttactt ttttgatgga acatgctatt
    16321 gtaacagctg tctttatctg ttcgttctta attgctttct tactaaaaaa cgatggacga
    16381 aatggattgc tgcgggtagt tattgctttt tagtcctacg gattgcgaca gagggttatt
    16441 tcttccacat gtcactagaa gatttgatac gactttggac aagtttggaa atcctgacac
    16501 aaacgtatca gttgggcttt tatctaaaca ttttgttagg aattttgttg ataataaagt
    16561 attttaaggt taagcaatag aaataataat ctgcctgatt atagatgata aactttttgt
    16621 ttttatctgg actgtgatat ttatagttct aaatggttta ttatttataa gtgttgaaag
    16681 agattgaaga aaatggcttc gtgacttgct ttcttcggtc tttttcgttt tattatcaat
    16741 ttgtaaacga tttacaattt gagtcaaatt atggtaaaat agtgtcatga gtaaaatgta
    16801 ctatgcagaa aatcctgacg ctgctcacga cattcatgag ttgagagtgg acttgttggg
    16861 agaaaaaatg acttttttga cagatgcggg tgtttttagc aagaaaatgg ttgactttgg
    16921 aagtcaactc ttgctcaagt gtctggatgt caaccaagga gagacagtcc tagatgtagg
    16981 ctgtggctat ggtccattag gtttgtcctt ggtcaaggtt tacggagttc aggcgaccat
    17041 ggttgatatt aacactcgtg ccctggattt agctcagaga aatgctgaaa aaaataatgc
    17101 aaaagcgacg atatttcaat ctaatattta tgcaagagtt caagggcgat ttgaccatgt
    17161 catttccaat cctcctatcc gtgcgggcaa gcaagtcgtt catgaaatca tcgagaaaag
    17221 taaagatttc ttggaaattg gtggagattt gaccatcgtc atccagaaaa aacaaggagc
    17281 tccaagtgcc aagtctaaga tggaagatgt gtttggcaat tgtgaaatcc ttaaaaaaga
    17341 caagggatac tatatcctta gaagtgtgaa agaatgagag cagttgattt aatccaaaaa
    17401 aaacgagacg gtcaagaact gacttcaagt gaaattgaat ggctgataga aggctatgta
    17461 tcaggaactg ttcctgatta tcagatgtct gcctttgcta tggctgttta ttttaaagga
    17521 atgacgactc gagaaatctc tgatttaacg atgaatatgg ttaagactgg gcaagagttt
    17581 gacctgtcag ccattgatgg tgtgaaagtt gacaagcatt ctactggtgg tgtcggcgat
    17641 aaggtaacct tgattttagc tcctcttgtt gctagcttcg gtgtgcctgt agcaaaaatg
    17701 agtggtcgtg gtcttggcca tacaggcgga acaattgata aattggagtc cattaagggc
    17761 tatcaagtag aacgtagtca agaggatttt attcgtcagg ttcaggatat tggagtatct
    17821 gtcattgggc aatcagacca gctggtcaaa gcagataagc ttctctatgc ccttcgtgat
    17881 gtgaccgcaa ctgtcgacac aattcctttg attgcgagtt cggtgatgag caagaaaatt
    17941 gcggcagggg cggatgctat tttgctagac gtgactgtcg gtgagggtgc cttcatgaag
    18001 acggttgatg aggcgcgtga gttggctcaa actatggtag atcttggtaa ggttgttgga
    18061 cggaagacag tagcagtgat tacggatatg agccagcctt tgggacgagc gattggaaat
    18121 cgtctggaaa tccttgaagc attggagatt ttgcaaggtc aaggacgtca ggatattacc
    18181 cactttattt gtgaattggc tcaaattatg cttggtttgg caaatgttaa caaaactgtt
    18241 gaagaagttc gccaacatct tgaaaatggt caagcactgg ctaagtttga ggaaatggtg
    18301 caagcccaag gtggagactt ggaagacctc tatcgtcctg taaatgtagc tcatgtggtg
    18361 gaaatccctg ctcaggaaac gggtgtcatt tcagctcttc cagctatgga ctttggtctt
    18421 tatgccatga ggctgggtgc tggtcgtgca gttaagtctg atgtcttgga ctatgaaaca
    18481 ggaattgttt ttgaaaagaa gattggagac tccgttcaaa agggtgaaat tgttgcaaaa
    18541 gtatacacaa atgaaaaaat tccacctcaa ctagttacag atttccaaaa atgtgttaaa
    18601 ataagtgatg aagtgaaaaa aatccgtgaa attgtagaaa tcatctccta aatggaggga
    18661 aaaccgaaat gaaattaaat aaatatatag atcatacgct tttaaaacaa gatgcaaaga
    18721 aaaaacaaat tgatagtttg ttgtctgagg ctagagagta tgactttgcc agtgtttgcg
    18781 ttaatccgac ctgggttgaa catgctaaaa aaggacttga aggcacagat gttaaggttt
    18841 gcacagtagt aggtttccct ttgggagcaa caacttcagc cgtgaaagca tttgagacaa
    18901 aagaagctat ccaaaatggt gcagatgaga ttgatatggt gatcaatgtt ggagctctca
    18961 aatcaggtaa tttagccttg gttgagtcag atattcgcgc agtagtggaa gcaagtggtg
    19021 ataagttagt gaaagtcatt attgaagctt gccttctgac agaccaagaa aaaattgttg
    19081 tttgccaatt ggcccaaaaa gctggggctg actttgttaa aacatctact ggcttttcaa
    19141 ctggtggtgc tacgatagca gatgttagat taatgcgtga aacagttgga tctgatatgg
    19201 gagtcaaggc tgctggtgga gctcgttctt atgcagatgc tcttgccttt gtcgaagcag
    19261 gtgcgacccg tatcggaacg tcagctgggg tagctatttt aaaaggagaa ttggcagatg
    19321 gcgactactg agttgattga actggcaatt gaaaccagca aacatgccta tgtcccctat
    19381 tctcactttc ctatcggagc agttttagta gccaaagacg gaagtgttta cacgggagtg
    19441 aatatcgaaa atgctagcta tcctttgacc aattgcggtg agagaacagc tgtttttaag
    19501 gctatatctg aaggccaaag agaattttca gaattgattg tctatggtca aactgaaaaa
    19561 ccgattttac catgtggtgc ttgtcgccaa gtaatggtcg aattttttga acaagattta
    19621 aaagtgacct tagtcgcaaa agataaatcg acggtcgaga tgacggtcgg ggagttactt
    19681 ccatactctt ttacagactt aaattagtct gagtcgctct ttgagtggca agggtctttg
    19741 tgaccaatca atccatactt gcaacatcgt tgcacatctt atttaggagg ttcagtaatg
    19801 aacaagaaac aatggctagg tcttggccta gttgcagtgg cagcagttgg acttgctgca
    19861 tgtggtaacc gctcttctcg taacgcagct tcatcttctg atgtgaagac aaaagcagca
    19921 atcgtcactg atactggtgg tgttgatgac aaatcattca accaatcagc ttgggaaggt
    19981 ttgcaagact ggggtaaaga acacaatctt tcaaaagata acggtttcac ttacttccaa
    20041 tcaacaagtg aagctgacta cgctaacaac ttgcaacaag cggctggaag ttacaaccta
    20101 atctttggtg ttggttttgc ccttcacaat gcagttgaag aagcagctaa agaacacact
    20161 gacttgaact atgtcttgat tgatgatgtg attaaagacc aaaaaaatgt tgctagcgta
    20221 actttcgctg ataatgagtc aggttacctt gcaggtgtgg ctgcagcaaa aacaactaag
    20281 acaaaacaag ttggttttgt aggtggtatc gaatctgaag ttatctctcg ttttgaagca
    20341 ggattcaagg ctggtgttgc gtcagtagac ccatctatca aagtccaagt tgactacgct
    20401 ggttcatttg gtgatgcggc taaaggtaaa acaattgcag ccgcacaata cgcagccggt
    20461 gcagatattg tttaccaagt agctggtggt acaggtgcag gtgtctttgc agaggcaaaa
    20521 tctctcaacg aaagccgtcc tgaaaatgaa aaagtttggg ttatcggtgt tgatcgtgac
    20581 caagaagcag aaggtaaata cacttctaaa gatggcaaag aatcaaactt tgttcttgta
    20641 tctactttga aacaagttgg tacaactgta aaagatattt ctaacaaggc agaaaaagga
    20701 gaattccctg gcggtcaagt gatcgtttac tcattgaagg ataaaggggt tgacttggca
    20761 gtaacaaacc tttcagaaga aggtaaaaaa gctgtcgaag atgcaaaagc taaaatcctt
    20821 gatggaagcg taaaagttcc tgaaaaataa tggatggaag tcatttctta ggaagcggcc
    20881 aagggccgct tttttaagag ttgagacaaa gtcattttgt ctcagtaaag cttgctacta
    20941 gacaaactag caagttttat tgaaataaaa taagactctg aaaggaagag cacatggcac
    21001 acgaaaatgt cattgagatg cgtgatatta ccaaggtgtt tggtggattt gttgccaacg
    21061 acaaaatcaa cttgcaccta cgaaaaggtg aaattcatgc acttttagga gaaaatgggg
    21121 ctggtaagtc cacgctaatg aacatgttag caggccttct tgaaccaact agtggtgaaa
    21181 tcgcggtcaa cggtcaagtt gtcaatctcg actccccatc taaagcagct agcttgggaa
    21241 tcgggatggt tcaccagcac tttatgttgg ttgaagcctt cacagtggct gaaaacatca
    21301 ttttaggtag tgaattgact aaaaatggtg tgctagatat cgctggagct agcaaagaaa
    21361 tcaaggctct ttctgaacgt tatggcttag ctgttgaccc ttctgccaag gtagcagata
    21421 tctcagttgg agcccaacaa cgtgtagaaa ttttaaaaac actttatcgg ggggctgata
    21481 tccttatctt tgacgaacca acggctgttt tgactccatc agaaattgat gagttgatgg
    21541 ctattatgaa aaatcttgtc aaagaaggaa aatcaattat cttgattacc cacaaattgg
    21601 atgaaattcg agcagtttct gaccgtgtta cagttatccg tcgtgggaaa tcaattgaaa
    21661 ccgttgaaat tgcaggggct accaatgctg atttggcgga aatgatggta ggacgttctg
    21721 tttcctttaa aacagagaag caagcctcta aaccaaaaga agtggttttg tctatcaaag
    21781 atttggtggt caatgaaaac cgtggtgttc cagctgttaa aaatctgtcc ttggatgttc
    21841 gtgctggaga gattgttggt attgcgggga ttgatggaaa tggtcagtct gaactgattc
    21901 aagccattac aggtcttcgc aaggttgaat ctggtagcat tgagctaaaa ggagattcaa
    21961 ttgtaggctt gcacccacgt cagattacag aactaagtgt tgggcacgtt ccagaagacc
    22021 gtcaccgtga tggcttgatt ttggaaatga tgatatctga aaatattgcc cttcaaacct
    22081 actataaaga accacatagt aaaaatggaa ttttgaatta ttcaaatatt acttcttatg
    22141 ctaaaaagct gatggaagag tttgatgttc gcgctgccag tgaattagtt cctgcagctg
    22201 cactctcagg aggaaatcaa caaaaagcaa ttattgctcg tgaaattgat cgagatcctg
    22261 atctccttat cgttagccag ccaactcgtg ggttggatgt cggtgccatt gagtatatcc
    22321 acaaacgctt gattgaagag cgtgataatg gcaaggctgt ccttgttgtc agctttgaat
    22381 tggatgagat tttaaacgtc tcagaccgta ttgccgttat ccacgatggt aagattcaag
    22441 gtattgtatc accagaaaca accaataaac aagaacttgg tgtcttgatg gctggtggaa
    22501 acttgggaaa ggagaagagt gatgtctaaa aaattacaac aaatttcggt tcccttgatt
    22561 tctgtattcc taggaatttt actcggagcc attgtcatgt ggatcttcgg ttatgatgct
    22621 atttggggct acgaagaatt gttctataca gcctttggca gtctgcgtgg gattggagaa
    22681 atcttccgtg ctatggatcc tctggtcttg attggtcttg gttttgccgt tgccagtcga
    22741 gctggtttct ttaacgtcgg acttcctggt caggctttgg caggttggat tctcagtggt
    22801 tggtttgccc tgtcgcatcc agatatgccc cgtcccttga tgattctagc aaccatcgtg
    22861 attgccttga ttgctggtgg gattgtcgga gcgattccag gtattcttag ggcctatcta
    22921 gggacgtcag aggttattgt aaccatcatg atgaactaca ttgtcttgta tgtagggaat
    22981 gcctttatcc atgctttccc taaagacttc atgcaaagta cagattcgac cattcgtgtt
    23041 ggggctaatg caacctatca gacaccttgg ttggctgagt tgactggtaa ctcacggatg
    23101 aatattggta ttttctttgc catcattgcc gttgcagtta tttggttcat gctcaagaaa
    23161 acaactcttg gttttgaaat ccgtgcagtt ggtcttaatc cacatgcttc agaatatgct
    23221 ggtatttctg ccaagcggac tattatccta tctatgatta tttcaggtgc cttggcaggt
    23281 cttggtggag ctgttgaagg tttgggaacc ttccagaacg tctatgttca aggttcgtca
    23341 ttagctatcg gatttaacgg aatggcggtt agtttgcttg cggccaactc accaattggt
    23401 atactttttg cagccttcct atttggcgtt ctccaagttg gggctcctgg tatgaatgcg
    23461 gcgcaggtac catctgagct tgtcagcatt gtaacagcgt ctattatctt ctttgtcagt
    23521 gttcattacc ttatcgaacg ctttgtcaaa ccgaaaaaac aagttaaagg aggtaagtaa
    23581 agatgtctat tataaccttg ctccccctct tggtgtcttc tatgctgatt tactcagcac
    23641 ctctcatctt tacaagtatc ggtggtgttt tctctgaacg tggtggtgtg gtaaacgttg
    23701 gccttgaagg aattatggtt atgggtgcct tttctggagt tgtctttaac cttgaatttg
    23761 cagaacaatt tggagcagca actccatggc tatccttgct tgtagcagga ttggttggta
    23821 gtgttttctc tatcatccac gcagcagcga cggttcattt ccgtgcagac catgttgtca
    23881 gcggtacggt attgaacttg atggcgcctg ccttggctgt tttcttagtt aaagttcttt
    23941 ataacaaagg acaaaccgac aacctaagtc aaacttttgg acgctttgat ttcccagtct
    24001 tggcaaatat cccagtgatt ggtgatatct tcttcaagtc aactagtcta cttggttatc
    24061 tggcgattgc cttctcattc cttgcttggt ttattctctt taagactcaa tttggtcttc
    24121 gtctccgctc tgtcggtgaa catcctcaag cagcggatac cttgggaatc aacgtctaca
    24181 agatgagata tttagggatt attatttcag gttttctagg tggaattggc ggagcgattt
    24241 atgcgcaatc aatctcagtt aacttctcag tgacaactat tgttggacct ggatttatcg
    24301 cccttgctgc gatgatcttt gggaaatgga atccaatcgg tgctatgctt tctagtctct
    24361 tctttggact ttcacaaagt ttggctgtta tcggttctca attgccgttc ctacaaggag
    24421 tgccagcggt ttatcttcaa attgcacctt atgttttgac aattcttgtc ttagcagcct
    24481 tctttggaaa agcagtcgca ccaaaagcag atggtatcaa ctacatcaaa tcaaaataag
    24541 catacaaaaa aacgtcagtc caatgactga actgcccccc aaaagttaga cagaaaaaat
    24601 ctaacttttg gggtgttttt attatgaaat taacttatga tgataaagtt cagatctatg
    24661 aacttagaaa acaaggatat agcttagaga agctttcaaa taaatttggg ataaacaatt
    24721 ctaatcttag gtatatgatt aaattgattg atcgttacgg aatagagttc gtcaaaaaag
    24781 gaaaaaatcg ttactattct cctgatttaa aacaagaaat gattcataaa gtctgacatg
    24841 aaggctggac taaagataga gtttctcttg aatacggcct cccaagtcgt acgatacttc
    24901 ttaactggct agcacaatac aggaaaaacg ggtatactat tgttgagaaa acaaaag
//
LOCUS       DAVHSY010000026        23490 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.027, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000026 DAVHSY010000000
VERSION     DAVHSY010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23490
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.027"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(287..520)
                     /locus_tag="VVR43_001347"
     CDS             complement(287..520)
                     /locus_tag="VVR43_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HEU6149704.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCN"
     gene            complement(734..2365)
                     /gene="rlmD"
                     /locus_tag="VVR43_001348"
     CDS             complement(734..2365)
                     /gene="rlmD"
                     /locus_tag="VVR43_001348"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU6149705.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHDLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2439..3413)
                     /locus_tag="VVR43_001349"
     CDS             complement(2439..3413)
                     /locus_tag="VVR43_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU6149706.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3487..4101)
                     /gene="pmp23"
                     /locus_tag="VVR43_001350"
     CDS             complement(3487..4101)
                     /gene="pmp23"
                     /locus_tag="VVR43_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU6149707.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4101..5075)
                     /locus_tag="VVR43_001351"
     CDS             complement(4101..5075)
                     /locus_tag="VVR43_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU6149708.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(5083..6339)
                     /locus_tag="VVR43_001352"
     CDS             complement(5083..6339)
                     /locus_tag="VVR43_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU6149709.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(6401..6832)
                     /locus_tag="VVR43_001353"
     CDS             complement(6401..6832)
                     /locus_tag="VVR43_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6149710.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6834..7436)
                     /locus_tag="VVR43_001354"
     CDS             complement(6834..7436)
                     /locus_tag="VVR43_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU6149711.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7420..8259)
                     /gene="prmC"
                     /locus_tag="VVR43_001355"
     CDS             complement(7420..8259)
                     /gene="prmC"
                     /locus_tag="VVR43_001355"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU6149712.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(8259..9338)
                     /gene="prfA"
                     /locus_tag="VVR43_001356"
     CDS             complement(8259..9338)
                     /gene="prfA"
                     /locus_tag="VVR43_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU6149713.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMLEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9335..9925)
                     /locus_tag="VVR43_001357"
     CDS             complement(9335..9925)
                     /locus_tag="VVR43_001357"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU6149714.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            10049..10231
                     /locus_tag="VVR43_001358"
     CDS             10049..10231
                     /locus_tag="VVR43_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU6149715.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10367..11740
                     /gene="mnmE"
                     /locus_tag="VVR43_001359"
     CDS             10367..11740
                     /gene="mnmE"
                     /locus_tag="VVR43_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU6149716.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11787..12722)
                     /gene="dapA"
                     /locus_tag="VVR43_001360"
     CDS             complement(11787..12722)
                     /gene="dapA"
                     /locus_tag="VVR43_001360"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU6149717.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     YPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     IPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12778..13854)
                     /locus_tag="VVR43_001361"
     CDS             complement(12778..13854)
                     /locus_tag="VVR43_001361"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU6149718.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14197..14269)
                     /locus_tag="VVR43_001362"
     tRNA            complement(14197..14269)
                     /locus_tag="VVR43_001362"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14234..14236),aa:Thr,seq:ggt)
     gene            complement(14369..14878)
                     /locus_tag="VVR43_001363"
     CDS             complement(14369..14878)
                     /locus_tag="VVR43_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU6149719.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(14876..14972)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15001..15432
                     /locus_tag="VVR43_001364"
     CDS             15001..15432
                     /locus_tag="VVR43_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU6149720.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15514..15891
                     /gene="mscL"
                     /locus_tag="VVR43_001365"
     CDS             15514..15891
                     /gene="mscL"
                     /locus_tag="VVR43_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU6149721.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKTAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(15933..17027)
                     /gene="hemH"
                     /locus_tag="VVR43_001366"
     CDS             complement(15933..17027)
                     /gene="hemH"
                     /locus_tag="VVR43_001366"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU6149722.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECI
                     CLILEPHYSFYSVMGYEKFLESQQIRFLVIKDWYQQQSLLDFWTDEIRKILRNEVGEE
                     SFKVIFSAHSVPIFALDYGDPYIDQIFDNSRLIAEQLGLMTDQYTNTWQSESDIGIPW
                     IKPDVLEYLREQKQHPEHYIFVPISFISEHIEVLFDNDVECYDLCQELGVTYHRPPMP
                     NTDSRLIDALVATVRANEDKEFKTFLPEEETFDELAPSATTKDIMKETDDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(17105..17891)
                     /gene="srtB"
                     /locus_tag="VVR43_001367"
                     /pseudo
     CDS             complement(17105..17891)
                     /gene="srtB"
                     /locus_tag="VVR43_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856390.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
     gene            complement(18006..19004)
                     /gene="srtG1"
                     /locus_tag="VVR43_001368"
     CDS             complement(18006..19004)
                     /gene="srtG1"
                     /locus_tag="VVR43_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HEU6149723.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(19022..20218)
                     /gene="pitB"
                     /locus_tag="VVR43_001369"
     CDS             complement(19022..20218)
                     /gene="pitB"
                     /locus_tag="VVR43_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
                     /protein_id="HEU6149724.1"
                     /translation="MKKTFFKKLFTASIAAITALSVFRGVPTFADDNSAITKANGENN
                     AVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHP
                     TADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMH
                     VIVKNKVNGGVYISSVYFKENNKSNAPKVEPSEQGVYNLFDNTYTKDASKEPNPDDPS
                     QVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEV
                     LAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTS
                     QGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTGLLIDNLPFILMIGLGLAGFVVLS
                     KKRREA"
     gene            complement(20263..20814)
                     /gene="sipA"
                     /locus_tag="VVR43_001370"
     CDS             complement(20263..20814)
                     /gene="sipA"
                     /locus_tag="VVR43_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HEU6149725.1"
                     /translation="MLLKKKHKKPVTQVNRDKSPPSVWGDILYLVSKLLMVGFVLATL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFSMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(20814..23411)
                     /gene="pitA"
                     /locus_tag="VVR43_001371"
                     /pseudo
     CDS             complement(20814..23411)
                     /gene="pitA"
                     /locus_tag="VVR43_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516426.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus tip adhesin PitA"
BASE COUNT         6710 a         4936 c         4429 g         7415 t
ORIGIN      
        1 tccctctttt tttcttcatt aaatttattt aattatagca taaatattga tttcattcaa
       61 tcttacattg atttagtgat ttgttttaga gaatttgttg tgttattccg tccttatttt
      121 gccataaatt gttttaagtg ggacctctta tccttaccat ttttacctcc taattttgag
      181 tataaaaaag acgatagagt ttttaatttc tatcgtctga gatttacata ttaaattttc
      241 atcacaaaat aagactcttt aaagaatctt taaattcatt ggtatgctaa ttacaatatc
      301 cattattaaa atggatacta taagcagcac accaactatt tattttttga gttttaaact
      361 ttggtagaag tcttgaactc cttatattta cataactatt tgcctctata actattatga
      421 cacgaaacca acaagcaagt tcaagcacct ccatatcttt attcaaatga ggactaagat
      481 attcacaaac tttatcataa acctctttat cttttttcat aaaaggggca tacaacttag
      541 caaatttatc ctaaaatttt ttgttgcctt tatcaatcat ttcaacactc ctttaaatat
      601 aaaaatgatc ctatcaatct ttatattgag cctattttct aattgatacc ttgcaagaaa
      661 ggaataatag ctgttcctat accaagtagg aatgtaataa atgcagaaag tcatatactg
      721 tcattctttt ctattaaatc attttgaagt gtctcaaagc atccatgatg gcttcttctt
      781 tttcaggtgt acactgtgga ataatttgtt tatccttttt agacttgttg taatgttctc
      841 gtaattctat tccacatttc ttttttatct gtgcaatata taatgtcgaa acttttaatt
      901 caaatttatt ccaaacatat tctttgattt gagcatatgt tgctttgctc tccgcacttg
      961 tcaaattcat ctcatccagc tcaatttcaa cacttatgtg cttatcgaca tcgagtttgg
     1021 acaaaagtgc taccgtctcg acgtgatgcg tttgaggaaa tagatccacc ggctggactt
     1081 tcttcaattc atatcccaat tcttggtaga gtttgatatc acgcgccatg gttgcgacat
     1141 tgcaggagat ataggcgatg cgatcggctc ctgtttgggc gcttgctttg ataaagcttt
     1201 ctgtcaagcc cttgcgtgga ggatcaacca agataacggt tggttgaatc ccatctttaa
     1261 gccaattctt catagcattt tcagctgtgt cacagacata gtgggcgttt gaaatattgt
     1321 tcagctgagc atttttttta ctattctcaa ccgcttctgg aatcagttca acaccgtaga
     1381 cttctttgac atgcttggcg actgataaac caatggttcc aataccagaa taagcatcaa
     1441 taaccacgtc atcttttttt aactctgcaa agtcaatggc tgtttgatag agtttctccg
     1501 ccatttcagt attgacttgg taaaaggctg ggccagcgat ttggaagtca tttcccaaca
     1561 tctggtccgt aatatagtct tgaccataaa gagtgcgcca ctccttacca aaaatcgcat
     1621 tggtattctg gtcgttgata ttttgcatga cagacacaat ctctgggaac tgcttgataa
     1681 cttgttcaat caattggtca acacgaaaaa cttttggacg agttgtcacc aaaacgacca
     1741 tgatttgtcc tgaatagtga ccacgacgca ccacaagatt ccgaatcaat ccagactgtt
     1801 ccttttcgtc ataaggtttt aaatcaaaac gacggagcag gtctcgaaga gctactacga
     1861 cttggtcaat gacaggatcc tggataaaga aatcttcaag gggcatgagg tcgtgcgaat
     1921 tcttacggaa aaatcctgtt tccaagacac cattcactcg acgaacgggc acctgcgcct
     1981 tattgcgata cttgactgga tgttccatac caagcgtttc agcaacttct acatctgcaa
     2041 ttccagcaat cttgtagaga ctgtccttga cttgcttggt tttaaacttg agctgttctg
     2101 gataagaaag gtgtcctaaa tccgcgattc ctgaacgcag gtaagccaaa tctagatctt
     2161 gattacggtg tggtgactgg acaaggtatt tttcaacttt tccaaagcca atctttttat
     2221 tgaccttgag gacacgcatg agaatttttt cactcggtaa agcattctct acaaaaaaga
     2281 ccaaaccatc taccttggca actcctgccc cttcatgggt caagtcaaca atttcaactt
     2341 ctacaatatc atttttcttt aacattcttt tctctttcta ttggccgaca aaaaagacgg
     2401 caacgttacg gttaccatcc attataccat gaaatttctt aagaaccaaa actcttgaag
     2461 aagttgacaa gggcttgcca gagggagctt aagaagttac caccgtcctc tagcgcctta
     2521 tccgcatcaa agttaaggtt gatattttta aaactgtcgc cagcttgtga tacgatgctt
     2581 tgtttaaggt catttagggt tttagtgaaa tctgcattgc tgaggatatc actctttgag
     2641 agattcaagg caaaattgat gatgatattg atctggtttc ctgttatgac ctgatcaagt
     2701 ttgtaatttt ttaaggtatc ttcaacaatc ttgcggatat cttcttctgt cagatttccc
     2761 ttgctttctt tagctttggc gagtcctgac ttgatatcag ctagggcaac gtttaattta
     2821 ttagcatcat agcctgattt gtccttgttt tcagcattga tatctgacaa agcttttagc
     2881 tcttcttgag ccaaatcttt attagcttgt ggcaccttgg ctccattagc ctctagcgaa
     2941 tagtaaatcc ctgctaaagc actttctcct gtaactggaa taggggctgc tacagtgatt
     3001 ttggcatgtt ccatacccag cgttactgct gcgtttcggt acatatcctg agtcacctta
     3061 gtgatatttt ctggtgtttc aatcttgacc tcaagtggcg atttgtcacc tagcttttga
     3121 atcttggctg atgaatacaa ctgtaagcta gagtcattgg ccacattcat gattttagaa
     3181 taaacatcag gtgtcatggt cttgagttct ttggtatctg ttgaggcatt gtagcccagt
     3241 tttttaagag tttgattttt ttggtcttca gatagggagg aacctaggac atattcaggt
     3301 tggacatagg tttcatcgat aactttttga acatctgttg ctgcatggac gctattcata
     3361 gctgttactg cccacaagac cgcagcacta gtcagaaaga gtttctttct catagggaat
     3421 ttcctccttt acttctttat agtaatatat ctatcttaaa gaaaacttat aacaaaaaca
     3481 cctggtctag ccagatgttg aaaagagagt gaaacatttg atgatgtaaa ggttaagtcg
     3541 tacctgtcta gaataataat agtttcctcc atttacatag agttcagcac cgtgaaaaat
     3601 ggaaatgggg tgaatataac tataagtctt tccagtcgta ttaccaagca agggggcaac
     3661 agtctcacga gagtactgtt tggctagagc caaggtattt tccttgccat tttgggcgat
     3721 aaaatcgata taggcaggtc caaaattata ggcttgaaca gctgtccaga tatctacacc
     3781 cttcttctgc gccagataga gattgcctgt cagagtttga atgccttgcc gaatgctaga
     3841 ggcattatca ttgatggtgt tggtggaacc acttgcagac tcactagact gcataacatc
     3901 gccttctttt ccttttgttt cagtataaat catagcaagc acaagctctt cgtttgctgg
     3961 ggtgtctttt tcactcaata tttctcgcac catgggttga taggtcatga cttgtttgac
     4021 atcttgatga acgcggtaag ctttatagcc agcaaaaagg aagactgcta gtacaagcac
     4081 tcttcgaatt cgtttaaaca ttatttactt tggatatcct cgatattttt gattaagata
     4141 gagtaggttc cattttcgtt ttggataaac tcaacagact cggcgtcttg atagacgtta
     4201 ttgggaacga tgagctcaat tccatttgat aaggagagtt tttggttttc aaatttcttt
     4261 aattggcgac tggcatcaat ttcatcaaat tgaacaggtt ctggtacggc ttctttgact
     4321 tggtcaataa agctcaaacg agccgtcaga ttgttgtcaa aaaggtcatt agccaatttc
     4381 tcaggtgaca attcattgct ttcttctagg ttgttgaaaa tagctgattt gaccttggat
     4441 tgaaattgaa aatcatctgt gttaaaagat tcagcaattc tctgggctgt tttttccagt
     4501 tccttgatag attttttagg agaaatctta ggagcgacag caagaagatt atctgaaaaa
     4561 tagttcaaaa aagtcccgtt gtacttgatt cgtttttcaa tcaggtgata cttgctactc
     4621 tgaagattga ccaccaaggc ctcatcagct cctgttccaa atccaggcag gttattctga
     4681 gttagcttga ttggattatc aacttctcct ccgaggtggg tcaaggtctc ccgcagggca
     4741 attcgcaaga aagcgaaatg ttctacacct tctttagaaa attgaacaaa aatcaagtca
     4801 ttggtcttga gattttcaga aatgctaaac tcctctttcc agagattagc cagcgttact
     4861 gatgtctcca acaaatcgtc tgtaatatga ttgaagaagg gattttcttc ttcgaaaatc
     4921 ccagtcttgg cttcatctga atacacatgt tcaatttttt tacgtaggta ttcttcgatt
     4981 tttggagtaa tattgagaaa cttatctgct aagaacagct cggtatcatc cggactgaac
     5041 tggtgaataa tggctttctt aatataaata tccataaaag ttttagtcct cgtataatgg
     5101 gaaggcatct gtcaattctt tgactgcact tctcacttct tctaatacag cctcattttc
     5161 tgaattctta agggttttaa tgatgagttc agccactttg cgactttctt cttcaccaaa
     5221 tccacgtgca gtaatagctg ctgctccgat acgaatccca cttgtcttga atggcgacaa
     5281 ggtttcgtaa gggattgaat ttttatttag ggtaatattg acttcatcca gcaagttttg
     5341 agcaactttt ccgttttcta caaccttagt cacatcaaca aggaagagat ggttttcagt
     5401 tccacctgaa ataatacgga aatcagggtc ttgcaagaag acatctgcca tagccttgct
     5461 gttcttaatt acattggcag catattcctt gaaggctgga tccaaaactt ctttgaagga
     5521 aactgcctta gccgccacaa catgctctaa aggaccgccc tgaatacctg ggaaaatagc
     5581 tgaattgatt tttttagcaa gttcttcgtc attggtcaaa atcaaaccac cacgaggtcc
     5641 acgaagggtt ttgtgggtcg ttgttgttgt gatatgagcg tatggaactg ggcttggatg
     5701 aaggccagcc gcaaccaaac cagcgatatg ggccatgtcc accatgagct tcgcaccgac
     5761 agcatctgcg atttcacgga attttgaaaa atcgataatt tgagaatatg ctgaagcacc
     5821 agctacaatc agttttggtt ttacttcttg ggcttgtttc aagatagcat caaagtctaa
     5881 gagttccgtt tcaggatcaa cactataaga aacaaagttg taggtttgac cagagaagct
     5941 aacaggagcc ccatgagtca aatgaccacc tgatgccaaa tccattccca taaccgtatc
     6001 acctggctca atcaaggaca tgtaagccgc acagttagct tggcttcctg aatgtggttg
     6061 gacattggca aatttagcac cgaaaatttc ttttgcgcgt tcaatagcaa gagtctctac
     6121 aacgtctact acatcagttc caccataata acggcgtcct gggtaaccct cggcatattt
     6181 atttgtcaag atagaccctt gagctgccat aacagccttg gaaactacgt tttccgaagc
     6241 aattaactcg atattatttt gttggcgttc ttcttctttg gcaatagcat tccagagatc
     6301 agcatcatat gctttaaaat catctttgtc aaaaatcata ggtcttctcc tttattgtgt
     6361 gactagtcca ttagtttgat tttacaataa gaaaatcaaa ctaaaagatg cgaataaacc
     6421 gtttctgcat tttatcacaa gtatagccaa ctttttcata aaatgcatga gcacccagac
     6481 gatgattggc agaatttaag cggataaacc cataaccaca tctttttgct tcttcttcca
     6541 acccttgtag taaactttta ccaatacctt gaccttgcgc ttgaggtgaa actgctaaag
     6601 ctaagatatt aaatcctgct ttggaataga gtgattcgta aacttcagcg tggacatatc
     6661 caagtaagac atgattagct gcatcctcat agccaagtag gaaatgatgg gaatcctgag
     6721 acagtctagc tagttggcta gccgtttcct ctggactaaa agtataaccc aaagcctctt
     6781 ggttgatgtc acatatcgct ttcacatctg tttcttgcaa atctcttagc atttcaagcc
     6841 tcctcaaaag aaatctctgg caaccgagca agaatatctt ctcgtttaat tgcgccttgg
     6901 cgtaagattt tcaccttgtc tccagacaaa tccacaatag ttgaatcctg tccagttaga
     6961 aaagcatcgt cttccagacc cagaacctct tggtcaaaat ccttcagaat ttgttcaaag
     7021 gttacaccac ttgcctgacc tgagatattg gcagacggcc caatcaaggg acctgtctct
     7081 cgaattaaat ccagtgtgat agggtgactg ggcatccgaa atccaatagt tgcaaggtca
     7141 gaatttaccc aatagggaac tcggtcattg gcttcgagaa taatggtcaa gggacctggc
     7201 aaaaaggtct ctacaagttt ttgtagataa gttggctgat tcttagaaaa gtgcaagata
     7261 tcctcgaaag aggcgatatt gagattgagt gccttatctc taggacgacg tttgagttgg
     7321 taaacatggt caactgcttt ttcatctaag gccttggcaa aaagaccata aacagtctct
     7381 gtaggtagaa cgacagctcc accattttcc aactcttgtc taatcctgtc catcatcaac
     7441 cacaaccatc ctattttgac caaattggtc tttgagtgtt cgaacttttt tttcaggaag
     7501 atgttttcta aaaagttcgg gaacactttg accttgcttg tatccaattt caaggtaaat
     7561 cttaccacca tccttgagat agtcttttgc atcttccgca attctacagt aaatagctag
     7621 gccatcctcg tctgcaaaga gagctagatg aggctccgaa tgcaaaacat tcaagcctac
     7681 ctctgactca tcttcacgag agatataggg tggattggat acaattatat catatttttc
     7741 agaaatttct gcaaaacaat cagatttttt aaaaaatata ttaagatttt gatcgctagc
     7801 attctctgat gcaagctcta aggcctcttg agaaacatct gctgctgtca ctgaccaatc
     7861 tggtctattt tttgctagag cgagagcaat agctccacta cctgttccaa tatccagaac
     7921 tgagagattc gtctcaagat tttcagttag aataagctcc actaactcct ctgtttctgg
     7981 acgaggaatc aaaacccgtt catccacctt taaatgcatt ccataaaaat ctgcctgtcc
     8041 aatgatgtac tgagctggct tgtgagctgc tagttgctgg taaatatctt ctacaaattg
     8101 tttttcttcc tctgttgtca cctcctgctg gagggcaaaa ataaagtctg taaaagatag
     8161 atttttcaga ctacgataga caaaagagag gctttccgct tcctctcctt gtcttatcaa
     8221 ctcttcttca aaatttgaaa ataattgagc taatttcatt atttgtttaa ttcttctagt
     8281 ttttgtgttt ggtcataaag caccaaggca tccacaactt cgtccaattt accagacaaa
     8341 atcgtatcta gtttttggag ggtcaagccg atacggtggt ctgtgacacg gttttgtggg
     8401 aagttataag ttcggatccg ttctgaacgg tcaccagtac cgattgtcga cttacgctca
     8461 gcgtcttgtt catcctgagc aatctgagca aagtggtcag cgacgcgtgc acggataatc
     8521 ttcatagcct tctcgcggtt cttctgctgg gtacgttctt cctgcatctc aaccttgata
     8581 ttggttggca agtgaacgat acgaacggca gtcgcaacct tattgacgtt ctgtccacca
     8641 gcaccagagg cgtgatagat gtcgacacga aggtcttttg gatcaatgtc gtattcaacc
     8701 tcttcaactt ctagcataac aagaactgtc gctgtcgaag tatgaacacg gccttggctt
     8761 tctgtcacag gaacacgttg cacacggtgg gcacctgatt catacttaag cttagagtat
     8821 acagactgac ctgaaaccat agcaaccact tctttaaaac caccgacacc attcatagag
     8881 gcttccatga cttcaaagcg ccaaccttgg gcttccgcat acttttggta catagttagc
     8941 aaatctccag cgaaaagtgc cgcttcgtct ccaccagctg ctccacggat ttcaaggatg
     9001 atattcttgt catcgtttgg atcctttgga aggagcaaaa ttttcagttt ttcttcatat
     9061 tcttcttttt cagccttggc atctttgagt tcttgcttgg ccatttcttc caagtccgca
     9121 tctccgcctg attccttaat catctcttcg gcatcgacga tattttgaag gacttgttta
     9181 tactcacggt aggctattac ggtgtcacga ttggaagctt cttcttttga aagctccata
     9241 aaacgcttgg tgtctgaaac gacatcaggg tcactcagca attctcctag ttcttcataa
     9301 cggtcttcta cagcttgtag ttgatcatag atgttcattt ttcttcattc tccttattga
     9361 tttcaggggc aaaataatgt ttacggcaaa ccgagatata ggtttcatta ccaccaatct
     9421 ggatctgttc tccatcgtaa acgggcagtc catcctgtgt tcgcaacacc atggtcgcct
     9481 ttttcttgca atactgacat atggtcttga tttcgtcaat cttgtctgct aaaagcaaga
     9541 gatatttgga accttcgaac aattcattgc gaaagtcatt tttcaagcca aaagccatga
     9601 cgggtatgtc taactcgtcc acaacacgag ctaggtcgta aacatggtgg cgtttgagaa
     9661 actgggcttc atcgaccaaa acacagtaag gtttttctgg taggtctcgg atatagccaa
     9721 agatatccgt tgtttcctca atcgcaaggg cagggcgttt catgccaatt cgactcgaca
     9781 catagccaac accgtcacgc gtatccagag ccgaagtcat aatgacaaca ccttttcctt
     9841 gctcctcgta gttataggcc actttgagaa tctcaatcgt tttaccagag ttcatggtcc
     9901 cataacgata atacaactgt gccatgtttc ttgcttcacg tccatttcta aatttttgct
     9961 acattctagt atatcataat tttcttaagc tttaaacggc aaaatgtggt aaaatagaag
    10021 aaatcaaaaa ctagtggagg aagctattat gccatttgta cgcatcgatt tatttgaagg
    10081 acgcacgctc gagcaaaaga aagctcttgc taaggaagta acggaagcgg ttgttcgcaa
    10141 cactggagcc cctcaatctg ctgttcatgt catcatcaac gacatgccag aaggaactta
    10201 tttcccacag ggggaaatgc gcaccaaata agctagctta agcagaattg cttaggcttt
    10261 ttcaatctcc aagtagcacc cattgaagaa atagtctaaa tttgttacaa tttgaaaaga
    10321 gacttggaaa attccaagaa aagagcaatt aattaaagga aatattatga ttacacgtga
    10381 atttgatacc atcgctgcta tctctactcc actaggtgaa ggagctattg gtattgtccg
    10441 cctgagcgga acagacagtt ttgctattgc gcaaaagatt tttaaaggaa aagacttgaa
    10501 caaggttgcc agccacactc tcaactacgg tcacattatt gatcctctga ctggtaaagt
    10561 catggacgag gttatggttg gggctatgaa gtctccaaag accttcactc gtgaggatat
    10621 tatcgagatt aacacccacg gtggtattgc ggtgaccaat gagattctcc agctagctat
    10681 ccgtgaagga gctcggttgg cagaacctgg tgaatttacc aaacgtgcct ttttaaacgg
    10741 tcgcgtagat ttgacacagg ccgaggcggt gatggatatc atccgagcca agacagacaa
    10801 ggccatgaac atcgcggtca aacaacttga tggttccctt tctgatctta tcaataatat
    10861 ccgtcaagaa atccttaaca cacttgccca agttgaggtc aatatcgact atcctgagta
    10921 tgacgatgtt gaggaagcca ctactgctgt tgtccgagag aagacaatgg agtttgagca
    10981 attactaacc aagctcctta ggacagcacg tcgtggtaaa atccttcgtg aaggaatttc
    11041 aacggctatc attggacgtc ccaacgttgg gaaatcaagc cttctcaaca acctcttgcg
    11101 tgaggacaag gctatcgtaa cagatatcgc tgggacaaca cgagatgtca tcgaagagta
    11161 cgtcaacatc aatggtgtac ctctcaaatt gattgataca gccggtattc gtgaaacaga
    11221 tgacatagtg gaacaaatcg gtgttgagcg ttcgaaaaaa gccctcaagg aagccgactt
    11281 ggttctacta gtgctaaatg ccagtgaacc actgactgcg caagacagac aacttcttga
    11341 aattagccaa gataccaatc gcattattct acttaataaa accgacctgc cagaaacgat
    11401 tgaaacttcg aaactacctg aagacgttat ccgtatttca gtccttaaaa accaaaacat
    11461 cgataagatt gaagagcgaa tcaacaacct cttctttgaa aatgctggtt tggttgagca
    11521 agatgctacc tacttgtcaa acgcccgtca catttccttg attgagaagg ccgttgaaag
    11581 cctacaagct gttaaccaag gtcttgaact agggatgcca gttgacttgc ttcaagttga
    11641 cttgacccgt acttgggaaa ttctaggaga aatcactgga gatgctgctc cagatgaact
    11701 catcacccaa ctctttagcc aattctgttt aggaaaataa gaaaaatcca tgatccttca
    11761 ttcggtcatg gattttattg tctttattag taatctggtc ttaagacccc tgttacagtt
    11821 gccttagttg cttcgtagtc gccatctacg acaaccttga taatgcgttt ggcatcttct
    11881 tctggtgctg gaataagagg tagacgagtg ggtccagctt caaatcccat atagttaaga
    11941 actgccttaa ctggagcagg acttggataa gagaagagag cattaacctt aggaatgaat
    12001 ttacgctgaa ttgctgcggc tttcttcata tcgctttctg caatggcagt aaacatctcg
    12061 tgcatttcat ccccatttgt atgagaggca acagaaataa ccccatccgc cccaaggttc
    12121 atggcatgga aagcatctcc atcctcacct gtataaatca agaactcttc aggcttgtgc
    12181 tcaatcaagt aagccatatt agccaagcta gtacattctt tgacaccgat aatatttgga
    12241 tagtcagcca agcgaagcat ggtttctgga gtcaattcga caactacacg ccctggaatg
    12301 ttatagataa taattggtag gtcagaagca tctgcaatag ccttaaagtg ctgatacatc
    12361 ccttcttgag aaggtttgtt gtagtaagga acaatagcaa gcccagctgc gaaaccacca
    12421 aattccgcta cttctttgac aaactcaata gagtcacgcg tatcattagt acctacaccc
    12481 gcaatcaaag gaacgcgtcc attgacaacc ttttgtacag ccgcaaacaa ctccaactcc
    12541 tcatcgtggg tcaaagttgg actctcagca gtcgttcctg cgagaagaat tccatccgta
    12601 tgatgggcca ataaatgctc aatcaaggct ggaatagcat caaagttaat ggaaccatcc
    12661 tcatggaagg gggtaataaa ggctgtaatg attttacatt cttttaaatc ttgataagac
    12721 acgaaaacac ctctctattt caaagaagga gttcatctga actcctaaac gatatgacta
    12781 ttttaattca aatttcaatt cggctgttgg acgaaccaat ccacgttcat gaagagtttc
    12841 agcaatctga actgagttcc aagcagcacc tttgagaagg ttatctgaaa caacccacat
    12901 gtgaattcct ttttctgcat ccaagtcttt acggatacga ccaacaaagg tatcacgcga
    12961 accaactgca ttgatggctt gaggatagat ttgatgagct acatcatctt caagaacagc
    13021 acctgggaag gctgcgatag ctgcttttac ttcttcgatt ggagccactt cttttgtttc
    13081 gatataaaca gactcagagt gagctgacaa gactggaata cgcacacatg ttgcagatac
    13141 tgcaatgcta tcatcttcca taattttctt agtttccttg gtcatcttca tctcttcgta
    13201 agtgtaatca ttgtcagtga agacatcgat ttgtggaaga gcattgaagg cgataggata
    13261 atgtttcttg tcaccgcctg aaggtaagat ttccgcatgc aaatcacgtg gtttcactcc
    13321 atcattcaag acctcacgaa gttcacgttg tgtctcaaga attgctccca taccagcacc
    13381 tgaaacggct tgataagttg aaacaatgat acggtccaag ccccattttt ggcgaaccgg
    13441 ctcaagagcc accatcattt ggattgttga acagttaggg caggcaatga ttccgttgtg
    13501 ggcatcaagt gcatgagcat tgacctctgg aacaaccaaa ggaacatctg gattttgacg
    13561 gaaataagat gtattatcca ctactaccac gccagctttt actgcgtatg gtgcatactt
    13621 agctgatgtc gaaccacctg ctgaaaagag agcaatatca actccttcaa aagctgtttc
    13681 agtcgtttct tcaatcgtaa tatcttgatc tttaaatttc aatgacttac ctgctgaacg
    13741 tgcagaagca aggtaacgga ttttatcgat tggaagtgtt gattcttcca acatttttat
    13801 catctgagca ccgacagcac ctgtcgcgcc gactacagca actgtatatc ccataaataa
    13861 cctctttcgg aattttctaa aaatttctat aatagaagta ttatactact ttttccatga
    13921 attgcaaagc tttttcatca ttttttggaa aataaaaatc cccaatcgct agactaggga
    13981 ttaagaggca tcttcatgtg atgagcaggt tcacacaact catcaaggtc cgctcctgcg
    14041 ttatgacctc cttatgctca atagtagtcc gaagactacc tatcgactca tcgcatattc
    14101 tatattacta gagatacttg attttgtcaa taagaaattt tttcgatcga gtataacaaa
    14161 aaactctcgt attcaagagt ttccctatac atatcatgct aattgccggg attgaaccgg
    14221 cgacctcatc cttaccatgg atgcgctctg ccaactgagc taaatcagct tacttaagaa
    14281 gtatactata ttcagaaaaa cttgtcaagt ttccttagaa attttccata ggaaaaagcc
    14341 aggtaagaac tacctagctt atcttcttct atttacttaa atcaattcga cgaccaattt
    14401 taccaataat aatcgctcca ataatcaatg aagcaaattc accgattcct gttgtaaacc
    14461 aagtaaggaa gaatggtaat tctgctacaa tatttaactc tgcagcgata gtaaacatgg
    14521 aaattgaaaa gaggattgaa aagaagaaat gatcttttcg aatcaatccg ttaaagaggt
    14581 aatccttgct atattttgca aaaagccaaa cacctaaact gaggaatact aaggttgaac
    14641 caccaccaac aaagacatct agcagtccga agctaaagaa attagcaatc atacaaccga
    14701 tggtaactcc gatgatgtac ttaggattgt aaaaagccat aaagttcatc atttctgaaa
    14761 tacgaaactg ataagcacca tagctgatgg catttagggg cggtgtgaca gtcaaaacga
    14821 cgtagatagc agcgacgatt gcaatatctg caacatcacg aatagttaat tttttcatct
    14881 tttctccttt ggcggttatc cgcgtgtaat atgcttggtg aaagaagcta agcaccaagg
    14941 gttgattcat tcaaccttac tagtatagca caatagcctg ctttatgcta tacttaaagc
    15001 atgaaaaaac ctattcaaaa attttttaac aatgaaatct tagcctatct cttttttggc
    15061 cttgcgacaa ctctagtttc gattctctca cgactagtca tttatcaact aagtcatcag
    15121 gaactccttg ctacggcctt ggcaaatatt atcggtatct tatttgcctt tatcacaaat
    15181 gatacgattg tatttaagca aaaaaagaaa aatagactta tccgtttagt gaaattttct
    15241 cttgctcgcc tttctacttt tctgttagac ttgtttttaa cttttctctt tgtaacccaa
    15301 tttcctcaca ttatagggca attcgtaact gaaaacattg ataagataaa tgctattgaa
    15361 acaataattg cacaaatatt cattattatc atcaattata tcttgagcaa ggtctatatt
    15421 tttagaaaat aatgctccat ttatgagcct tttaattgcc ttctataatg atttaggata
    15481 caatgaaaca cgaaacattg aaaggaaaac agtatgttaa aaaatctaaa atcgttcttg
    15541 cttcgaggaa atgttattga ccttgctgtc ggtgttgtca ttgcctctgc ttttggtgct
    15601 atcgttactt cacttgtaaa cgacattatc actcctctta ttttaaatcc cgctttgaaa
    15661 actgctaaag tcgaacgtat cgctcaactt tcttggcatg gagtcggcta tggtaacttt
    15721 ttaagtgcta ttatcaattt tatctttgtg ggtaccgccc tcttctttat tatcaagggc
    15781 attgaaaaag cacagaaact gactggcata aaggaagaaa aaactgccga aaaaaaacca
    15841 accgaattgg aagtccttca agaaataaaa gctctccttg agaaaaaata atcgattaaa
    15901 aggatctagc gcaaagctaa atcctttttt ctttactctt tgggtaactt gcctgctttt
    15961 tcaagcattt tcttgatcag ataaggcatc ttaacatttt cacgaccttt tttctcaatg
    16021 agttttttga caaattctgg catctgaagg tcgtctgtct ctttcatgat gtccttggta
    16081 gttgccgaag gcgctaactc atcaaaggtt tcttcttctg ggagaaaagt tttaaattct
    16141 ttgtcttcgt tggctcttac agtagcaact aaagcgtcaa ttaaacggct atccgtattg
    16201 ggcatcggtg gacgatggta agtgacacct aattcttgac acaaatcata acattccaca
    16261 tcattatcga acaagacttc gatgtgctca ctgataaagc taatcggaac aaaaatataa
    16321 tgttctggat gttgcttttg ttctcgtaaa tattctaaga catctggctt gatccaaggg
    16381 attccaatat cgctttcgct ctgccaagta ttggtatact ggtctgtcat taggcctagt
    16441 tgttcagcaa tgagcctgct attatcgaaa atctgatcga tataaggatc tccatagtcc
    16501 aaggcaaaaa tgggaacgct atgggctgaa aagattacct tgaaggattc ttctcccacc
    16561 tcatttcgta aaatttttct aatctcatct gtccagaagt ccagcaaaga ctgttgttga
    16621 taccagtcct taataactaa aaatcggatc tgctggcttt ccagaaactt ttcatacccc
    16681 atgactgagt aaaaagaata atgaggttcc aaaatcaagc agatacattc ttcaacacca
    16741 tcagtttcca tctgcttgat cacgtctgga ataaagggac gagaaaattt gttggcaaag
    16801 tagataccgt actcctcccc taaacgttct ttgactaaat tgacctcctc acgtgtaatc
    16861 cgctgcaaag gcgtcccacc gatacgaata tagttgtcat agagagtctg gatttcgtgg
    16921 tcttggggtc taactccacg acgaatgttt gtaaagaatt ctgctactcc ttcaaaacta
    16981 atctcctctg gagatccaaa ggtcatcatt aatatggctt ttttcatgtt atcatcctta
    17041 tgatattatt ttctctatcc attctatcat gaaagaaaaa aatagtaaac gtttcctacg
    17101 tctactattt cttttgctct tttgtttttt tatctcgtct tataattagg atgataagga
    17161 caagaagtgg gaattccgtg atcgaaatac cgtgttccta ctgcttcccc actttcatcc
    17221 tgtgctactt tcaccggtgc atccgttatt ttagctaaaa ggatatgtcg tccattagtt
    17281 atgttaagga aacaggtgct taataaaaca atcttgtccg ttgaggtcaa ggaaacatct
    17341 cgcttgtact tggctttact tagcagatat tgatagtaag cctggtgttc ctcatccttg
    17401 gaactcaagg ttcgataaat ctccgtgtca taggcatcca cttctaaaat cccaaaaatt
    17461 tcaagaccac gttctcgacc attgtagtag atagaaccgt agcgatgctg gtcgaagaat
    17521 tccttatcag caaatttctt aatctcaccg aacatagccc ctgaagccat agagtgtccg
    17581 tagatgatcg tattaaaatc agtaaagttg ggattaaagc gatagtcgag aaaaattgat
    17641 cccgttatcg tataatcgcc aaaggcattg cggtcaaggt atttgacatt atcctgactt
    17701 tgtagaagcg gatagtctac cttggtccca tcaaggctaa tccaaccgca aacatctttg
    17761 ttcaagtgct gtagggtttc aaaacctgtg ctcgaagcat ccttttcaat aggattatag
    17821 tgatcatagt cacttgcttc tactactctc tgccaactaa aaagagctac aaaaacacag
    17881 aagaatacca gaaatacgtt tttaaatcgc gctcttttga accgtcatca gcactccttt
    17941 ctatgcgaga tttcttaaaa ggaaaggagg cgggacaaaa ccgcctcttt tctattcacc
    18001 cttagtcagt aaaagggtct gcttcttgca ttttttttac tctctcttct acgacgtagg
    18061 atcaagtaga ggacaaggag taagaaaatc aagagcaaga acaatacaaa caagataagg
    18121 taccaaatcc atagtgggat tgatgagagg aaacgtccaa gagacgagtc atcaaagaca
    18181 ctgtatggaa atggttttga tttttttgta tggaaagtat ttttagggac agtgtctgta
    18241 atctttgcga ctacgatatg acgaccattg gtcacatcga gaaaacaggt actgagtagg
    18301 atgatacgat cactcggtga gagtgagata tcccgcttgt gcatggcgac tgagagcagg
    18361 tggtctagat aggcctgctg gcggtcctca ccctgtattc ctggatcata gatgttaaag
    18421 tcataggcat caacctccaa catctcaaag atctcgagcc ctttttccac accattgtag
    18481 tatatactac cgtaacgatg ctggtcaaaa aattcctgat cagcaaactt agccacatca
    18541 ccaaacatga ccccattttc tacgtggtgc ccgtagataa tggtattaaa gtcttcgaac
    18601 ttaggattat ttcgtgcatc gagaaagata gcgcctgtcg ctgcaaactc acctttggag
    18661 tccttgttga gatacttttc attgtccttg gcttggacta agggatagtc gatattggtg
    18721 ccgtagacat tgatccaacc gaggacttcg ggattgagtt cttggagttt gctgaagcct
    18781 gaaaaactgg ccagctcatc ctgttgcgtc gtgacaggtc gataagcttc gtactcactt
    18841 gacgaagcta aggagtagac ttggttggaa tcccaaaggg cgtagaaacc aaagagaaag
    18901 atcaaagctg caaaaatgag cagcaagtga ttgatcaccc catccacagc aagaacgaga
    18961 cgcctagaca gactcttttt tggtttctca cgcttggttt tcatcatctg cccccagccg
    19021 tttaggcttc tctacgtttt ttagacaaga caacaaatcc agccaaacca agaccaatca
    19081 tcaaaatgaa tggaaggtta tcaatcaaga gaccagtagg agtaacgtcg tcgattttgt
    19141 tagtaacttt gttgtcgttt ttcttttcac ctatgaggat atctgttaat gtaaaatcta
    19201 catttttttg tccttgagat gtttgttctg caccatttgt agtataaatt gatgaatctg
    19261 tataacctgc tactccagtt tcagttactg tatatttaga acctgctggt agttgttcaa
    19321 ctgtaaatgt ttcaccatct ttaagagtaa aattgtactc aactgtatct gctggggtca
    19381 ctactgccaa cacctctgac ttagatccat gttttactat aatattcgta acaggggttt
    19441 ctgctgtttt atttgtactt ggaagttgaa tcttgatatg gaattggaaa tctcttgttt
    19501 tatcccctga agctccatca acttttttag taattgttaa tgctttcgca ttggggtcta
    19561 cttgactcgg atcatcagga ttaggctcct tacttgcgtc tttggtatat gtgttatcaa
    19621 ataaattata aacgccttgt tcacttggtt ctactttagg ggcgttagat ttattatttt
    19681 ccttaaagta tactgatgaa atatagacac caccatttac tttattctta acaataacgt
    19741 gcatttcata tgtacgtttg tcgtatctca tggcatcaat tgttttacca tttttggtaa
    19801 tcgcctgcca tccagttttt gcttccgcta catcataaac gtattcacca gcatggccat
    19861 aagcaactcc cgaaaaaatg tcttctgttg ctttttgaat cttatcagca gttgggtgat
    19921 catttttatt gtattctaca tttctatctg gaattgcaac tccggtttga tatggcgcac
    19981 cgttagaaga ttgtcctgtt ttttctgtaa acttaaatgt aaatgtcgct gttggtgttg
    20041 ttattccctc tgcaatattc aacgttttat taatcttcac aacagcatta ttttcaccat
    20101 ttgctttggt tattgctgaa ttatcatccg caaaagtcgg gacacctctg aatacggaca
    20161 aagcggttat agctgcaatg cttgcagtga atagcttttt aaagaatgtt tttttcatga
    20221 ttatttcttt tgttttttta ttttcttttt tcattatgat catcaaaagc ctcgtcttct
    20281 aattactgtt acaacttttc cttgagtatc ctgtataggg atggttccaa aagcacgact
    20341 gtctacagcc gttgttcgat tgtccccgag gacaaaaagt tgtcctgctg ggactttcat
    20401 cgagaaggtt gccccttcct tatagagcag cgtttctttg tagatatctt gctcttgttg
    20461 aggagaaccg ttgatgatga gaccattttc gtttatatcg attgtacttc cttcggttgc
    20521 tatgacacgc gccactcttt ccttaccttt ataactatag actagcaaat caccaatcga
    20581 atagcgttta tccaacctat aatagacgac caagtcgcca tcttttaagg cgggcttcat
    20641 gccatcgtca ttgtatctta ataatccaaa gacgaaaaag taaagggtgg ctagtacaaa
    20701 tccaaccatc agaagtttac tgactaagta aaggatatct ccccagacac tcggcggaga
    20761 cttatcccga ttgacttgtg ttactggttt cttatgtttc tttttaagca gcatcacttc
    20821 ctcctattca ccacaaggtg accaagtaag atgataaaga agatccctcc tagaggaaga
    20881 acgactccaa gcacgagagt gctactcaag aagtcaattc ccgtttcagg tacgctgttt
    20941 ttattattcg tgactgtcgc agacttattt gcatcaagag ttccttcttt tttatcatag
    21001 gacacctgat acccacgaga cgaacttgct tcttcttcga tactataacg agcatttaga
    21061 ggaaggtcga gaatcttgat ggttttatct ttctttagat caactgtcgc cttaccattg
    21121 gtgaattgta gcgttgtttt ttgattattt actattgcac tatacgatcc attcaatggt
    21181 ttattttgcg catcctttac gttaatggta atcttaaagg attgcagaag attagcaaaa
    21241 gcacctgtaa ctttttttgt gactgaaagt gtcggaagtc tgtggttggt gacgattgtt
    21301 tgaacatcct ctgacaaagt cccctcttgt ttttcatagg tgacatgata tcccgttcta
    21361 gagttctcta cttcttccac cttatagtgg gtatcacgag gcagataact gagggcagtt
    21421 tcctgactat ttttgagaga aatctgtgct ttcccgttag tcactgttgt attcccaaac
    21481 ttgccgttaa tcggcttgcc atccttatct gaaagggtaa cattaattgt gaaagattta
    21541 ttaggtgatt gttcaccttc taggattttc tttacggtga gacttggaag ctgtcggtaa
    21601 ataactttga aggatggttt ctctttcgta cctgtctttt gaacttcgac tgtgtatccc
    21661 ggagcgtctg gtgctttcag ttcgtagtca tatcccttag ctacctttgc aaaactagta
    21721 ttttcagtaa aactattcgt ttgaactgga ctagtgacct ttcgatagga atcctttata
    21781 cttccatctt tcttttggtt taagtttaat tcgacactag gtggacgatt tgctgatgga
    21841 tttgattttc catccacacc tttccactca atctctacag gaaccgtcaa tggatctgac
    21901 ggcttgaaag tgggcttctc agaatagtct tttattttgg tacgtgaggt cccaatacca
    21961 taggaatagg caacttttgc ccccttgttg gagtagagtt tagtagcatc ggcttcttcg
    22021 gcatcatcac tagtaagtgt cttatcaccc gcaatcgcat caaatgcctc ttggctagag
    22081 gtgacagtaa acttgagaac gtacttggcg tcatcctcca aagtgtaact cggattaaac
    22141 ttggctgtta cttccactaa tccctgttcg ttcttcttag tttcaatcgt aacttgattg
    22201 tcattcagtt cttgctcgtt accatccttg attttgacga cacgaaggtg tgaagcatca
    22261 ccaggtaaca gctgcacgta cttggacaag acatctgata tagttacatg gtgtacgcct
    22321 agaggtagaa ttttatctgt gatttctttg aatttttgtt gcaagtcatt ttcattattg
    22381 gcagaaaata tttcgttggg gattccagaa ttataaccac tgatatatcc tttaagagat
    22441 gtgatactat cgtttgaacc tatatatctg aatttgattg aataaaagcc atctattttt
    22501 ggagctatta aactagatat attcagcatt cctctctcta aaccagaggt aaaccaatat
    22561 ggagtatcaa tcatacgtcc cacatttgga ttagaataat agttatatat tgttctccca
    22621 ctattagact cgtaatacat attagcttcg ccatctgaca gcagaataac tacttttttt
    22681 gccccagccc ttgcactttg caacaatctt tgagcttcag ttaacccagc atttatattt
    22741 gtcccagtgc caatgcccgc gtccatacca taagaatgac tagagtcagc aattgttaac
    22801 gaactaacaa tattttttga gctattagaa tccgtgctcc aagatactaa agttttagca
    22861 tcatcatatg aagagatatt tgaataccaa ccagctcaat ttggccaagt tccatattga
    22921 taactcagat aatattcatt ataataacgg ccattatact gattatcaat ctttccggca
    22981 aaaccaacta tagacagacg gttttgggaa ttagaaagaa ttgtatcaat gagcccctga
    23041 cgaccattca cacctttcag tgtatgtttt agtgcttcaa tcctactaat gtatcgtcta
    23101 ctagagtaag accacacatc tcgctcttcc atactccctg aaaaatcggc aaccaagact
    23161 acatccaagg gttctgactg ggtctccgtc tgggtctccg ttcccagttt agatgtgata
    23221 tccagtgaca actcatactg gtcttcttgc cctgatatcg gagtaatcgt tttgtgcaga
    23281 gttgtctgag gttcagttgt tgaatctgca cgtaaagaat taattggtgc acacaaaaaa
    23341 agaatagcga gaaagataac taaactactg gtaaaatatt gaatcttctt aaaatcatat
    23401 tgaacgttca tgctatctcc cttgctagaa tatgttttaa tctgatacta tataaatctg
    23461 agacttccat aagataattg tataataata
//
LOCUS       DAVHSY010000027        23472 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.028, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000027 DAVHSY010000000
VERSION     DAVHSY010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23472
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.028"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(<1..334)
                     /locus_tag="VVR43_001372"
     CDS             complement(<1..334)
                     /locus_tag="VVR43_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6149726.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKVLLEGCSQRSVSLDYALPNQGMLSFWLAQYKKN
                     GYTIVEKTR"
     gene            complement(707..2677)
                     /gene="tkt"
                     /locus_tag="VVR43_001373"
     CDS             complement(707..2677)
                     /gene="tkt"
                     /locus_tag="VVR43_001373"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU6149727.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYNDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKFP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            complement(2714..3409)
                     /locus_tag="VVR43_001374"
     CDS             complement(2714..3409)
                     /locus_tag="VVR43_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU6149728.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLESTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            complement(3420..4505)
                     /locus_tag="VVR43_001375"
     CDS             complement(3420..4505)
                     /locus_tag="VVR43_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEU6149729.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            complement(4531..4842)
                     /locus_tag="VVR43_001376"
     CDS             complement(4531..4842)
                     /locus_tag="VVR43_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEU6149730.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            complement(4870..5319)
                     /locus_tag="VVR43_001377"
     CDS             complement(4870..5319)
                     /locus_tag="VVR43_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6149731.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            complement(5297..5725)
                     /locus_tag="VVR43_001378"
     CDS             complement(5297..5725)
                     /locus_tag="VVR43_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6149732.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            complement(5718..7181)
                     /locus_tag="VVR43_001379"
     CDS             complement(5718..7181)
                     /locus_tag="VVR43_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU6149733.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKV
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFTELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            complement(7710..10046)
                     /locus_tag="VVR43_001380"
     CDS             complement(7710..10046)
                     /locus_tag="VVR43_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEU6149734.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQAKK"
     gene            10179..10928
                     /locus_tag="VVR43_001381"
     CDS             10179..10928
                     /locus_tag="VVR43_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU6149735.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            complement(11221..11835)
                     /locus_tag="VVR43_001382"
     CDS             complement(11221..11835)
                     /locus_tag="VVR43_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU6149736.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(12651..12920)
                     /gene="rpsO"
                     /locus_tag="VVR43_001383"
     CDS             complement(12651..12920)
                     /gene="rpsO"
                     /locus_tag="VVR43_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU6149737.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            complement(13061..13690)
                     /locus_tag="VVR43_001384"
     CDS             complement(13061..13690)
                     /locus_tag="VVR43_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU6149738.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     FYIDETKTTRLLDTSDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKECISLLEK"
     gene            13928..14128
                     /locus_tag="VVR43_001385"
     CDS             13928..14128
                     /locus_tag="VVR43_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149739.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKELYINNLL
                     FFTPLVILIVSLLYSYRFRFSL"
     gene            14558..14698
                     /locus_tag="VVR43_001386"
     CDS             14558..14698
                     /locus_tag="VVR43_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU6149740.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            14705..14881
                     /locus_tag="VVR43_001387"
     CDS             14705..14881
                     /locus_tag="VVR43_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU6149741.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            14939..16882
                     /gene="thrS"
                     /locus_tag="VVR43_001388"
     CDS             14939..16882
                     /gene="thrS"
                     /locus_tag="VVR43_001388"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU6149742.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(16931..17905)
                     /locus_tag="VVR43_001389"
     CDS             complement(16931..17905)
                     /locus_tag="VVR43_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU6149743.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(17898..18575)
                     /locus_tag="VVR43_001390"
     CDS             complement(17898..18575)
                     /locus_tag="VVR43_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6149744.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            18731..19804
                     /locus_tag="VVR43_001391"
     CDS             18731..19804
                     /locus_tag="VVR43_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU6149745.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            complement(19895..20197)
                     /locus_tag="VVR43_001392"
     CDS             complement(19895..20197)
                     /locus_tag="VVR43_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149746.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPNYLSMLFDFY"
     gene            complement(20265..20702)
                     /locus_tag="VVR43_001393"
     CDS             complement(20265..20702)
                     /locus_tag="VVR43_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU6149747.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQISLEKVVADAESQMKD"
     gene            complement(20778..21620)
                     /locus_tag="VVR43_001394"
     CDS             complement(20778..21620)
                     /locus_tag="VVR43_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU6149748.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHIGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            21732..22382
                     /locus_tag="VVR43_001395"
     CDS             21732..22382
                     /locus_tag="VVR43_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU6149749.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            22363..22554
                     /locus_tag="VVR43_001396"
     CDS             22363..22554
                     /locus_tag="VVR43_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149750.1"
                     /translation="MSRKSTNFSSPLPTLKVLFSGFYFYHFILLSFGGRIFEKNGRVF
                     EKKKGSLTYEKITKNFCYI"
     gene            22580..23226
                     /locus_tag="VVR43_001397"
                     /pseudo
     CDS             22580..23226
                     /locus_tag="VVR43_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            23357..>23472
                     /locus_tag="VVR43_001398"
     CDS             23357..>23472
                     /locus_tag="VVR43_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter permease"
                     /protein_id="HEU6149751.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFIPNHSYLSQLDVTYKT"
BASE COUNT         7204 a         5248 c         4214 g         6806 t
ORIGIN      
        1 ctcttgtttt ctcaacaata gtatacccgt ttttcttgta ttgtgccagc caaaatgaaa
       61 gcattccttg gtttgggagg gcataatcaa gactaacact tctttgtgaa caaccttcca
      121 gtaagacttt atccatcatt tcttgtttca atttagaaga atagtgacga ttcttcccct
      181 ttttaacgat ttctatgcca taacggtcaa ttaatttcac catgtacttt agaccagaaa
      241 catccacacc aaatcttttt gaaagctgtt tgaagctttg tccttgcttt cttagttcat
      301 agatctgaac tttatcttca taactcaatt tcataataaa acaccccaaa agttagattt
      361 attctgtcta acttttgggg tgcagttcat catttcaaca tcctatacta tgcgtttttt
      421 aattttagag accttctctc tagctttcaa aaaacttaca atatcctaag tcaatctgtg
      481 gatgctgtgt ttattgatta aagaaactat ctagatcagt agcaaagtga ttagcgtact
      541 tcgcaaccgt ttcagagtat actctattct gtatactatc tactataact ttcgtagata
      601 aattattaca ttctcattat agtttttaaa taaccaatca tctgattagt gtctatcact
      661 acatctgcta gtctgacaac agctgtatct tcattgtaat tggtttctat agggacttaa
      721 cttgagcaac gatattctct accgtaaatc cataattatc aatcacagtc tgagctgggg
      781 cagacgcacc gaagatgtca ataccgatga ccgcgccatc caaaccaaca tacttgtacc
      841 aactttgggt cgctgccatt tcaatggcca cacgacgacg agtcttagat ggtaaaatgt
      901 cttccttgta ggtagcatct tgagcatcaa atagttcggt tgagggcata gataccacac
      961 gtactttacc accttgtaaa accaattcct tagcagcttt gatagctaga ttgacctcag
     1021 atcctgtagc aatgataata gtatcaaatc ccggggtatc atacacgacg taggctcctt
     1081 tagcgacctt accaaagtct gtcccttctt caactaccaa gttttgacgg gttaagacaa
     1141 tgacagttgg agtggtggta ctggtcaagg catgatgcca agccgcttga gtttcacggg
     1201 catccgctgg acggataaca gtcaagtttg gcattgagcg taaacctgcc aaatgttcaa
     1261 ctggttcatg agttggacca tcttcaccaa cggcaattga atcatgggta aagacataag
     1321 ttacaggcaa ctcctgaatg gctgatagcc gaatagcagc tttgacgtag tcagagaaaa
     1381 caaagaaggt tccgccataa actcgtaaac caccatgaag agccattcca ttgaggattg
     1441 ttcccatggc aaattcacgt accccaaact gaatattgcg gtttaatgga ttatatttat
     1501 cttgtaagcc atctgccttg atgtaggtca tgttggagtg agctaagtct gccgatccac
     1561 ctaagaaggt tggtaaaact gctgctgctg tattaatagc atcttgggac gaattacgag
     1621 ttgcttgaga gaagccattc tcatagacag ggaagtcttt ttcagtaatg gttacaggga
     1681 attttccagc tacaatagcg tcaatctcac tagcaacttc gggataagca accttgtaat
     1741 cagacaccaa actagcccaa gcatcgtatg cctcctgacc acgatccgct acatttgtct
     1801 tgaaatcaga atatacttcc tctggtactt caaatggatc gtaatcccat cccaaaaact
     1861 tacgagttgc tcctgtttct tctgctccta gtggtgcacc atgaacagca tttgtaccac
     1921 ttttattggg tgagccgtaa ccaattaccg ttttcacttc aatcaaactc ggcttaccag
     1981 aaaacttggc cgtctcaatt gctgtagaaa ttgctgctaa atctgttcca tcttctacca
     2041 gaactgtatg ccaaccataa gcatcgtaac gggcgcgaac attttcagag aaagtatctt
     2101 tggtctcacc atccaagcag atgtcgttgg agtcgtagag gacgataagc ttatctaaag
     2161 cttgatgacc tgcataagaa gccgcctccg cagacactcc ttccatgaag tcaccgtctc
     2221 cagcaataac ataagtataa tggtcaaaaa tagggaaacc atctttgttg tacttagcag
     2281 ctaaaaaacg ctctgcttgg gcgaaaccaa cggcagtaga aattccctga ccaagcggac
     2341 cagatgtcgc atccacacca gacgtatgcg tcacttcagg atgaccaggt gtcttagatc
     2401 cccattgccg gaaattttta atctcgtcca tggatacatc gttataccct gttaaatgca
     2461 agagagcata cagtagcatt gatccatgac ccgcagacaa gataaagcga tctcggttaa
     2521 tccagtttgg ctgctcaggt gtaattctaa ggtgctttgt aaataggcta taagccattg
     2581 gcgcagcacc catgacgatt cccgggtgac cagaattaga tttgttaata gcatctacgc
     2641 caagaaaacg aatggcgtta actgattgta gtgacatata ttcctcctaa ctaataaatt
     2701 tcttctcaaa ccattatttg attggcattg tttttccggt catttcttcg taatctctag
     2761 aacagatatc ccaggctttg gcaatatcgt catccaaacc aaataatcca ctacgaccta
     2821 taacataaat atctggtcct gccacatcaa tttgtttgaa agtcttacga ctcgaagaac
     2881 catccatctc aatgatgtag tgataaccat tctgaactct aagctgacgg agttcttgga
     2941 ttttatacaa ggtagactcc aaaaagcgtt gtcctgcaaa acctggatct acagtcataa
     3001 tagttacttt gtcaagtaaa tcaatgtagg gaaagattgt agaaacaggt gtttcaggat
     3061 taaggacaac accagccttt agacctgcat catgaatttt atcaatcaaa cgaaaagcaa
     3121 gaccattcag aacttcagca tgaatacaaa tatactcaca ttgtaaatcg agaacttgat
     3181 ctacccaaaa ggttgggtct gtgaccatca gatgaactga taaaggtgtg tcactaattt
     3241 tttgaacttc ttgaatgaac caaggagaca aggtaatatt gggaacaaaa tggccatcca
     3301 taatatcgat atgataagat gctactttat cattcaaaaa agtaatctgc tctttgaatt
     3361 tgtccaaatc catggtcatc aaagatggtg aaaattcaat tcttgacatc gttaccctct
     3421 tacaaaattt caatatctga caaatcaatc tcttcttcaa cagtcataac tggttctgta
     3481 tgttttattg gttttttcaa aatcgcgtag acaagtcctg tgactacaat gttggctaac
     3541 aaagcacaaa taccagctac tggacgagtc atggttggta acataagcac tccaccaaat
     3601 ggcacggcag aatcagcacc cattgtcaaa gaaacagcac caccaacagc accaccgata
     3661 cctgttgcaa tgagacctgg aaccaagtta ttcataacaa tcggaattac accttcaaca
     3721 atattgacaa tccccatagg aacagccgat ttcaatgttt cgatttcctc ttgagtatag
     3781 atattttttt tgagtaattt cgcgataaaa taggccaatc caaatccaac tggtgtagca
     3841 gtattcacca attgcaaagc agtcaatggt tctttcacac cttcagcctg taaagtcaac
     3901 acaaacgcat agactgtttt attaagtggg ccaccaaagt caacagcact gagaactcca
     3961 ataactgccc ccatcaaacc atttgaagca cttcccaagc tttgtaataa gctcgtcaac
     4021 cagttggtaa aggctgcgat aggcgctcca ataatataaa tcataatcaa actacttacc
     4081 aaagaggcta caaaaggaat aatcaaggtt ggcattaaac ctttaatcca gtttggtact
     4141 ttgacctttt taataatcgc ttgaaccaag aaaccagcta tataacctcc caagatacca
     4201 ccgataaacc ctgaaccaac agaattggca attagaccaa caacaaaacc tggtgcaatc
     4261 cctggtttac cagcaatcga gtaagacaaa cctgtagcaa taacaactgg caagagacca
     4321 agggctttac cacccatagt tgctaaagca tcccagatag tgaattttcc tgctacaaga
     4381 gcgtcaggaa caccaccccc cattgctaaa ccaatggcaa ctaagaatcc tgcaccacaa
     4441 acaattggaa tcatatagga aatggctgtc aataagtgac cttttaagtt taagtgtttc
     4501 aacatatatt ttctccttaa atattttcag ttatttcgta acaatctcaa cagctttagc
     4561 aatcagttta ttgggagatt tgactgccac ttctgttgga accttgataa tctttttacc
     4621 ctcaaagcgt tccataccag aaatcttaac atcaactgct aaaataacta catccgctgc
     4681 atcaatctgc tcttgactca attcattttc tacccctatt gtcccctgag tctcaacatg
     4741 aatcacatgt ccagctacct ttgcggcatt ctctaatttt tcctgtgcaa tataagtgtg
     4801 ggcaattccc acagtacaag ctgcaacacc aacaattttc atacggatac cctccaaaat
     4861 tttttcttat taacaaaaag ctgcaatcac atcatcagat gtctgagccc gaactaattt
     4921 ggcaacaact tcgtcattac caagttttcg agcaaagagt gataaggtct tcaaatgctc
     4981 cctagcagct tctgtatcat caccaactgc aaagagtaca attactttga cccctttccc
     5041 atcaatggtc tcccaaggaa tctcattgtg atttatagct atgactaccc ccgccttctc
     5101 cacagcagaa ctcttgctat ggggaatagc aatataattc ccaataccgg tctgtccttc
     5161 tgcctctctc tgataaagac cttcgataaa ttggtctcta tcagacacat aacccgtctc
     5221 aaccaatagt tgagctaatg cctcaaaaac ctcttctttg ctctgcatct gtaaatccgt
     5281 ctggatcaga ctcacattaa gaatatcttt gatttccata tattatctcc cgtaattctt
     5341 cttttgttaa ctgttttaat tgatttatga atgattcatc tgctagtctt ctcatcaatg
     5401 ttttaataca tgacttgtcc tgtgatactg caatggccaa accgataata aggtcaacac
     5461 actggatatc cttcgaccat tctctgatag gtgattttaa tctagtaatc actaagacat
     5521 gatgttgaaa gtttccttca caatgtggta gaagaacacc tttagcaacc tctatacttc
     5581 cctgtctctc acggtaatat agaagctctt ctattttttc tgtatcttca gaaacaagaa
     5641 ggctgatttg atttgctaat tctttgtagg cttcttgacg attttgaaca gatatatcca
     5701 taaggacaag cgaaagatta ttcatagttt atctcctgaa tttttgcttg aagacgttgt
     5761 ttatcaccct cggttagaaa aacactaact aggacaaacg ggacacttgc tggttcctgc
     5821 aaagctaccg tcgtcacaat gaaatctaaa tctggatata gatttatcag ctcatctaat
     5881 tgatgataag caactacatc aataatatcc aattcagtaa attgcttttc taatcgtgct
     5941 cgtaaaagct ctgaagttcc gacacctgat gtacacatca ctactgtttt tagaggacgt
     6001 gctcgctttt cttgaaaccg tgcaaaatat aagactagaa aaccaatctc gtccagactc
     6061 aaggacgcaa aaccaaatac tagactcact tctttagaaa tagttgttaa ctctttaacc
     6121 agattaggat aggttaaaag aatttgtgat aaaagactat tcttaatctg tactctatta
     6181 tctaatctcc tcagtaaggg actgatatga ctcgccaagt caacaaagtc aggatctgtc
     6241 gtttcaatct ctctattgtc catacacata cggctaaaat agtaatgagt gacatctaaa
     6301 actcgctgag aaaaaggaag cttcccggaa gaaaatggtt tttgcaatct cgaagataca
     6361 acgtattgat aaagatagtc aatctcaact gcatcaacct tcatcttaaa atattgttca
     6421 atttcttgaa taattttttg acagacactg taaattttct catcaacaat agtaggtttt
     6481 gaaggtgcta caacatgaat actagtacta cgacgattcc tactgataaa aatatacagg
     6541 tgagagaaaa tatttatatt atatggatag ggaatgttta cccccaattc tctctcaagt
     6601 gtaatcagta atcccaaaca aaagtgagca agttctccgt caagaggctg aaccttattc
     6661 tgtgtaattt gctctaaatc caactgatta aacattggca gtagatttag aatggctgaa
     6721 cgaatttgag cctcatcccc atcaataaaa agctttcgtt gtctcatttt taaatctaac
     6781 ccataaattg ctagactctc ttgtaatatc tgacgatctt ttagtactac tgactcgctt
     6841 acgtagaatt cctctcctaa atcataaata gaatgtggct taggagcagt caacaagaga
     6901 cgttctagta atttttcacg ccttacttca ggatcaaaag cctctgtaaa attcccatca
     6961 acgtccacga gggaacttct tggatttaat ttgaagcctc tgcctttttc agataaaatg
     7021 aatgcttcta ccggacaatc tttgttgatt accttgacaa ggcgataaac cgttttatca
     7081 gagcaattta atttttctcc caatacttta gcagatatat aatccttact atctcgcaaa
     7141 aggagcaaca acgtttccat ttgttcttgt tttctagaca cgatacacct cctttatgat
     7201 tccattatat cgctttcaaa aaataatata cttcgcattt tgtcctttgc aatggacatt
     7261 tttgttttta tcaaaaatat gatatcaaat agaacagaac ctcactatgc caaaatcatt
     7321 ttaccttttc ttcataacat ctattttagt tgaaatattt aagttgcttt tcgtatttga
     7381 taagaaataa accaaacgat tttctaataa ataacactat gttccattta acaatagata
     7441 gcatcttcat tttcaaacta ccaacctatc cgaccatttg ttctagcaat agaagagagt
     7501 taaaattact tcaatctgtc gctttctctt tcttacatca aacttcaaat agtctaacta
     7561 cagatatttg aatctattac ctcaatccaa gcaggcttga gaatcactct tgggttcacc
     7621 gatagataat agacatgtag gccttgcaca tcagatctac gatagatcca tcgtataaaa
     7681 aactgcaatc cacagattgc agtctttctt tattttttcg cttggtaacg actggtcagg
     7741 atgaaaatca cggtaaagac caacatcatg acaccataaa caggtaatgt ttgtcctgtt
     7801 aaggttgaaa tttcaagcag tttttggatt cttgggaaga gagctgtggc taggaagcct
     7861 cctactgacc agacaatcaa gaggacacgc catagggtga atggcatgca ggctctaaat
     7921 acggataaga aaccaattga ccccaagaga taatagagga gagttgagat ttctaactca
     7981 gaccaacctt ggctactccc aaatattttc acaaacagga cgctgaagac gaccatgaga
     8041 gcgcttggta gggcacgaag catggatttt ctgaggaaat ttggctcaac aggtttgata
     8101 tttcgctcaa aagtcagaac gaatggtggg aaaccttcca caaactggtc aatcatggta
     8161 atctggattg gaatgaaggg gaaaatcaag atccattcag accgacctag taaagcactg
     8221 gcgatacaga taactgcgag caagaatgag tagatggtct ttatcaagaa aatcggggcg
     8281 atgtgggcaa tgttattgac cacgcgacga ccctcgaaga gaatctcagg aacatcatta
     8341 aagtctgagt tcaagagaac cagattggca atctgacggg ttgctggatc tccctccgcc
     8401 atcacgatag aacaatccgc ctcacgaagg gccaagatat cattaacccc gtcccctgtc
     8461 atagccgttg tatgacccgc ttttttcaac gtttggatga tgagtttctt ttgatgaggg
     8521 gaaacacgtc cgaaaatagc tgtctcctcc gccatggcca tcaattcctc atcggtgatt
     8581 tttgagcaat ctacatagct gtgatagtcc gcaaaaccag ccttctgggc aatgctggac
     8641 accgtaactg gattgtcacc agagataatc ttgagtccca cctcttgaga acggagatag
     8701 tccagcgtct ctgctgctcc ctctcgaatg gggtccaaga tttccagcaa ggctagagcc
     8761 tgaatatcag atggtttctg tggtttgtga tggtctaatt tctcctgact gagagctaag
     8821 accaagacac gtgaacctct ctccaaggcc tctctggctt ctgggacctc agaatccagc
     8881 aacatctcag gtgcccctaa gaaaactgtc cccaagcctt ctaactccat agccccccac
     8941 ttgcggtcgc tcgagaaggg aagattggaa atcataggat aagcaacatc tcccacaaaa
     9001 cgctggcgaa tggcttgggc agttggattc ttatcctcac tatgggccat gtagctggtc
     9061 aagatgctgg caatagcctc ttcaccatac gtttccgtca acggaagaac agcctccacc
     9121 tgcatctttc cttgggtgat ggtacccgtc ttgtccagac agagcatatc cacgcgcgcc
     9181 aaggtctcaa cagagtacat ctcctgcacc aagacctttt tcaagcccaa cttaatcact
     9241 gcagtcaaga gcgaagtaat ggtcaaaagg gcaattccct taggcaacat tcccaaaaga
     9301 gctgtcgacg agtttacaac ggatgacttg agaggcaggc cttttaaaag caaggcttcc
     9361 agcaagagag ccagaccaaa gggaatgata atcttcccag taaaaccagc caacttgtcc
     9421 agcgatttca tgatacggga gttgatgggt ttaacggtct tggcttccag cataagtttg
     9481 gcagcatagt tgtctgcacc gacatggtga acttgagata aaactgaccc actggctagg
     9541 aaacttcctg acaaaagtaa gccgtcaact tccttttgca ccaaatcact ttctcccgtt
     9601 aacatggctt cattgacttc cgcaaagcct tccaaaacca aggcatcact aggaatctgc
     9661 tctcctgcag acaaacgaat gacatctcct agcactaatt cttcaggatt aagagcaact
     9721 tcctgaccat cacggatggt tttgaccttt tccttggtca tgagattgag cttgtccacc
     9781 atgtgtttgg ctcgtagctc ggtcacaatc ccagaaaaag cgttaaagca gataacagca
     9841 aagaagacca gattgctcca agcctgcaca aaggcaaggg ccaaagcaat ggcaaagttc
     9901 aaagcgttaa aaagggtaaa gacatttcgt ttaacgattt gccaagtgct ggtactggct
     9961 gatgcggtaa agtcattgac caaaccctca gcctgtcttt ccttgacttc tctttgggtt
    10021 aatcccataa tcttattttt atccataaat tctattatat catttttttt aacagaattc
    10081 taatttcatc ccaaatatgc atctagtcaa gggaaaagtt tgccagccct cctttgataa
    10141 ggtataataa taacaagaaa acaatcgaag gagatcgcat gttttatact tatttgcgtg
    10201 gattagttgt attgctctta tggtccatca atggcaatgc tcactatcat aatactgata
    10261 aaattcctaa tcaagatgaa aattatattt tagttgcgcc tcaccgtacc tggtgggatc
    10321 ctgtttatat ggcctttgcg accaagccaa aacagttcat ctttatggca aaaaaagaac
    10381 tctttaccaa ccgtatcttt ggttggtgga ttcgtatgtg tggcgccttt cccatcgacc
    10441 gtgaaaatcc cagcgcctca gccatcaaat atcctatcaa cgttctcaaa aaaagtgacc
    10501 gctctctcat catgtttcca agtggtagcc gccactcaaa cgatgtcaag gggggcgcag
    10561 cactgattgc caaaatggcc aaggtccgta tcatgccggt tacctacacc ggtcccatga
    10621 ctttgaaggg cttgattagc cgtgaacgtg tcgatatgaa ctttggaaat ccaatcgata
    10681 tctcagatat caagaaaatg aatgatgaag gcattgaaac agtcgccaat cgtattcaaa
    10741 cagaattcca acgtctggac gaagaaacga aacaatggca caatgataaa aaaccaaatc
    10801 cactctggtg gtttatccgc atccctgccc tcatccttgc tattatcctc gctatcctaa
    10861 ccatcatctt tagctttatc gcaagcttca tctggaaccc agataagaaa agagaagaac
    10921 ttgcatagaa gaaatgaacc ttggccaaac agctaaggtt ttcatttata tatcaaattg
    10981 aaactagaat agtacacctc tacttcttaa aacattttta gaaatcgatt tgactgtcct
    11041 gatcgatttg tcctgttttt gtttcatttt actatattta taagaatctc ctaatcaaat
    11101 caaaagccac tctacaatag agtaacttta agattgtcca tttatactca atgaaaaagc
    11161 cctctgaaaa tcagagagct gatttgagct cgggctaaaa tcctagtgaa acaaaaaaat
    11221 ctacacgatc agaaaagtct ctatcgtgcc attttcatac atgatgtata gtccaagtag
    11281 aatgaatact aagggcacaa tgattcgctc gtatttttca attgtctcga atattaacgg
    11341 aatagaggat aacacccgac taatctcgca aaagataatt atgccgatta caaacacaag
    11401 caaggccacg agggtctgtg accaatctaa cgaagcaaaa taaggtatat agatacctaa
    11461 attatctccg ccagacgcaa ttgtcagcaa tgtaactgtc caaaacagtt gatttgcctt
    11521 gctttgttct aatctttcaa taatttcttc ctcttcttct tccgcatctt ctccaacaat
    11581 tgcaaagcga atccctaaat agatagggat taaaccaagc aatccaacca tccattcttc
    11641 aggcacgaaa ttaacgacat aagcagcaac taaactcgcc cctacaagta agcctgtgcc
    11701 tagatattgc cccgcataaa tatgccattt ctgtttattc tgtgatagct gtgcaaataa
    11761 aataattaaa ataattaaat aatcgatact ggtggaaata taaacaccaa tagcagatat
    11821 gattgtctgt cccataaaaa aaacctcctg tattagtcag taataaatca gcagatttta
    11881 ggagagcaca gacacattaa tttagctatc gctagtgggt aatgtcgaac gtaggaaagc
    11941 attttactcc tcctcaaaac gtagttacaa agtaatttct aactggaatt cagtgactac
    12001 ttccatgtaa agtataacat actatacttt actttgtaaa gagtgggctc ttctaggggg
    12061 cttgcataca gctactcggc ttgaaaagcc gagtaactgc gcacctttat ggtgtaatta
    12121 gctgatacca tttgaggttt ttgtagtctc caaaattgtt accgataaaa cctcaataaa
    12181 aaagccctct gaagtcagag agctgatttt agcccgggct aaaatcctaa tgaaaaagat
    12241 gaaactcctt gtgctcatcg aacactgtgt catttcccta ttttcatacg gatttttgac
    12301 gcccttagca tcatgattct tgctagataa atcgtttata gactaggcga cgaggcgaag
    12361 atcgtacgaa actttcagtg aaacaaaaaa aatctccccg aagggagaaa agctagttta
    12421 ttttacctta cagtgctagg aaccgtaacc gaagattata cttgagtata gcgaggtaag
    12481 gtgacaacgc aaaaaagcta cccaatttag agtagcttta ttatcaagat atgctcaatt
    12541 gaacacggcc taagcacttg gcaaaaaaga taaaatctcc tagaaactga agtttcttcg
    12601 tcaattttcc tatttttgct ttgtgctttt gacagccttt gtatcttgaa ttagcgacga
    12661 agtcctagag agttgatcaa ctcacggtaa cggttaacgt cgtttttacg caagtatgca
    12721 agcaagttac gacggcgacc gatttttttc atcaatccac ggtaagtagc gtggtctttt
    12781 ttgtgttgtt tgatgtgttc attaaggtgg ttgatttccc aagtaaggac agcaacttga
    12841 acctctactg aacctgtatc accttcgtga cgtgcatatt gtgcaatgat ttcatttttt
    12901 ttctcttttg agattgccat gatgtttctc ctttttattt ggcttcatcc gagtgacagg
    12961 ttggcatgcc tgtaaccaag aagaagttat ttgtctttac gacaatccct attttaccaa
    13021 gatttaaatt ttctgtcaaa cattaatact ctcatagtta ttatttttca agtaaagaga
    13081 tacattcttt tatatgatga cctttttcaa gttcatctac caatccaata gcataatctg
    13141 cataactaat ctggcttatt cctttttcat tagtagtaaa aatttctcct gctagaatgt
    13201 agtttcctgt tttttcacca tcgggaataa aatctacagc aggactgaca aaagtccagt
    13261 tgagattatt ttttgtacga agaagatcca attcatccgc ttgagctttt gctagtggct
    13321 taaattcttc aggaaaatca gacgtatcta aaagtcgtgt cgtttttgtt tcatctatat
    13381 aaaagcttcc tgatccccct acaactagaa aacgtgtctg tgttccagca agaagctgat
    13441 taaatagttc gattgatttg ctgtggagcg gtagcgtatc tggtgtataa gcaccaaacg
    13501 ctgaaataac agcatcaaat ccagtaagat catcttttgt caactcaaat aaatcttttt
    13561 taataataga ctcagcttga cttttgtttt cagaacgaac aatagccgtt acttcatgtc
    13621 ctcgtttgac tgcttcttca acaattgcct tccccgcttg tccatttgct gcaataactg
    13681 ctagtttcat tttttatacc tctcttgttg taattatttt agttacaaca attgtgacac
    13741 tcttaataat caatgtcaat agtcttgctt aattattatc aaaatatttc taccaagaaa
    13801 actaactatg attctagtga aaagaaaaat cttctttgtc aacaaattta ctttcttgtt
    13861 ttaaacatgc tataataatc atagcaagag atctaagttg tctgtttttt aaaacgaggt
    13921 gattatcatg cgtagattct attcccatct cccctactat ctggtcatat tattctttta
    13981 ttggccactt tatgagttgt tcttactagt tgtttctgac ccccttacac tcaaggaact
    14041 ctatataaac aatcttctct tctttacacc tctggtaatc ttgattgtat cgttactcta
    14101 tagctaccgt ttccgtttct cactttgatg gttagttggt aacggactgc tcttttactt
    14161 tactatcata acctttggtg agtttatact aatttacttg ctaatctatg aaacagttgc
    14221 tctggtcggc atggattctg gtattagcat caagcatatt ctacaaaaaa tgaaaaacaa
    14281 aaactttcac aaaatccttg aaaaatctca caatcatgct ataataatcc atagagacaa
    14341 gtcacttagt ccctttctac tagagagtgc gtggttgctg gaaacgcata ggaagtctaa
    14401 actgatacta ctcttgagtt ttttatgaaa acataaaacg gtggccacgt tagagccgat
    14461 cagaggtgtc cctctctttt gaggtacata aatgaaggtg gaaccacgtt gcgacgtcct
    14521 ttcgaggatg tcgcattttt ttattaggat actaattatg gagttgcaag aattagtgga
    14581 gcgcagttgg gcaatccgac aagcttatca cgaactggaa gttaagcatc atgatttcaa
    14641 gtggacggta gaagaagacc tcttggcttt atctaatgat attggaaatt tccaatgact
    14701 ggtgatgaca aagcaaggac gctactatga tgaaacaccc tacacactgg aacaaaaact
    14761 ttcagaaaat atctggtggc tattagaact ttctcaacgt ttggatatag acattctgac
    14821 ggaaatggaa aacttcctct ctgataaaga aaagcaattg aacgttagga ctcggaagta
    14881 gtctgctgat aaaaaatcaa tgcttagaaa ctatgaaata ataaaaaagg agaacatcat
    14941 gattaacatt actttcccag atggcgctgt tcgtgaattc gaatctggcg taacaacttt
    15001 tgaaattgcc caatctatca gcaattccct agctaaaaaa gccttggctg gtaaattcaa
    15061 cggcaaactc atcgacacta ctcgcgctat cactgaagat ggaagcatcg aaattgtgac
    15121 acctgatcac gaagatgccc ttccaatctt gcgtcactca gcagctcact tgttcgccca
    15181 agcagctcgt cgtcttttcc cagacattca cttgggagtt ggtccagcca tcgaagatgg
    15241 tttctactac gatactgaca acacagctgg tcaaatctct aacgaagacc ttcctcgtat
    15301 cgaagaagaa atgcaaaaaa tcgtcaaaga aaacttccca tctattcgtg aagaagtgac
    15361 taaagacgag gcacgtgaaa tcttcaaaaa tgacccttac aagttggaat tgattgaaga
    15421 acactcagaa gacgaaggcg gtttgactat ctatcgtcag ggtgaatatg tagacctctg
    15481 ccgtggacct cacgttccat caacaggtcg tatccaaatc ttccaccttc tccatgtagc
    15541 tggtgcgtac tggcgtggaa acagcgacaa cgctatgatg caacgtatct acggtacagc
    15601 ttggtttgac aagaaagact tgaaaaacta ccttcaaatg cgtgaagaag ctaaggaacg
    15661 tgaccaccgt aaacttggta aagagcttga cctctttatg atttcacaag aagtgggaca
    15721 aggtttgcca ttctggttgc caaatggtgc gactatccgt cgtgaattgg aacgctacat
    15781 cgtaaacaaa gagttggctt ctggctacca acacgtctac actccaccac ttgcttctgt
    15841 tgagctttac aagacttctg gtcactggga tcattaccaa gaagacatgt tcccaaccat
    15901 ggacatgggt gacggggaag aatttgtcct tcgtccaatg aactgtccgc accacatcca
    15961 agtttttaaa caccatgttc actcttaccg tgaattgcca atccgtatcg ctgaaatcgg
    16021 tatgatgcac cgttacgaaa aatctggtgc cctcactggc cttcaacgtg tacgtgaaat
    16081 gtcactcaac gacggtcacc tattcgttac tccagaacaa atccaagaag aattccaacg
    16141 tgcccttcag ttgattatcg atgtttatga agacttcaac ttgactgact accgcttccg
    16201 cctctctctt cgtgaccctc aagatactca taagtacttt gataacgatg agatgtggga
    16261 aaatgcccaa accatgcttc gtgcagctct tgatgaaatg ggcgtggact actttgaagc
    16321 cgaaggtgaa gcagccttct acggaccaaa attggatatc cagattaaaa ctgcccttgg
    16381 aaaagaagaa accctttcta ctatccaact tgatttcttg ttgccagaac gcttcgacct
    16441 caaatacatc ggagctgatg gcgaagatca ccgtccagtc atgatccacc gtggggttat
    16501 ctcaactatg gaacgcttca cagctatctt gattgagaac tacaagggag ccttcccaac
    16561 atggctggca ccacaccaag taaccctcat cccagtatct aacgaaaaac acgtggacta
    16621 cgcttgggaa gtggccaaga aactccgtga ccgcggtgtc cgtgcagacg tagatgagcg
    16681 caatgaaaaa atgcagttca agatccgtgc ttcacaaacc agcaagattc cttaccaatt
    16741 aattgttgga gacaaagaaa tggaagacga aacagtcaac gttcgtcgct acggccaaaa
    16801 agaaacacaa actgtctcag ttgataattt tgttcaagct atcctagctg atatcgccaa
    16861 caaatcacgc gttgagaaat aagagtctag cataaaagcc tccaatctgg aggctttttc
    16921 tcatctattt ttactcaagg actaagttca cttgagcaaa ctgaatccgc actgtcgttc
    16981 cttttccgac ctcagactcg atacgaatct ggtgccccag ttcttcagaa attttcttag
    17041 atagataaag gccaagtcca gaggactgct gggtcaaacg gccattgtat cctgaaaagc
    17101 cacgttcaaa tactcggagg acatcactgt tttttatccc gattcccgta tctttgatac
    17161 aaagctcttg gtcatccata taaatctcca gaccaccttc cttggtgtac ttgagactgt
    17221 ttgagatgat ttgctcaata accactagca gccacttttt atccgtcacg atttctttat
    17281 caaggtcatg tagattgaca tttaagcctt tttgaataaa gaaaagagca tatttacgaa
    17341 ttatttcctt gaccaagtcc tcaatttgaa cctgctttaa gagcaaatca tcatggaaac
    17401 tttctaaacg caggtactgt aaaactaggt tggtatagga gtcgattttg aaaatttcct
    17461 gttctagctg ctgcttcagt tggcggtcga ccacttctgc aactaagagt tgactggctg
    17521 caatgggggt ctttatctga tggacccaca aggtatagta atccagcaaa tccgtcagtt
    17581 ttctttctgc ttttgacctc tgctgataga gttccatctc acgcgcttct aatttttctg
    17641 ctaaagctat ttccaaagga gacttggctt ccctctctcc atagagaagt tcctggcgat
    17701 agacctgcgt ttccaccaat atgtcccaag tgaaaaataa tatggttaca aagcaacaca
    17761 agaagaaaaa gtagaggaag taaattccta gactggcaaa taaaaactga aagagtaaga
    17821 caagaaatgc caaagaaagc agatagataa aaagacgact acgggagcgc agataggcta
    17881 gaaaaaattg tttccaatca agcatgcttc aatccgtacc ctattccttt cttggtctcg
    17941 ataaatccta ccaatccctg ctcctccaac tttttacgca aacgagccac attgacagag
    18001 agggtattat catcaatgaa aaagtcactg ttccaaagtt cccgcatcag gtcgtcacgt
    18061 gctacgatgt tgcctgcatg ctcaaataac acgcgtaaaa tctggaattc attcttggtc
    18121 aaattcaaga cttgcccttg ataatgtaaa tccatggatt tggtattgag gataacacca
    18181 gcatattcca gcaaactctc atcacgccca aactcatagg aacgacgcaa caagccctga
    18241 accttagcta aaagaacctg ctggtcaaaa ggcttggtca caaagtcatc cgcccccata
    18301 ttgattgcca tgacaatatc catagcctgg tctctcgaag aaagaaacat gataggtacc
    18361 ttggaaatct tgcggatttc ctgacaccag tgataaccat taaacaaggg caaaccaata
    18421 tccatgagga ccagatgagg ttccgactga acaaatagac tcaaaacttc cataaagtct
    18481 tctaccagga ccacttcaaa tccccattca gagagcattt tcccaatctg ttgacgaatg
    18541 acctgatcat cttctattaa taaaatcttg tgcatgcgct tctccttttc tattattata
    18601 acagattttt ccatgctaga tggtctgaaa ctgaatttga aatagcctgt ttttagccag
    18661 tacaaacagg ctatgctact agctaatttg agggaaattt gctaagataa ataaaaagaa
    18721 aggagctctt atggccaata tttttgacta tctgaaagat gtcgcatatg attcttatta
    18781 cgaccttccc ttgaatgagt tagacattct aaccttaata gaaatcacct acctctcctt
    18841 tgataatctg gtctccacac ttcctcaacg tcttttagat ctagcacctc aggttccaag
    18901 agagcccacc atgcttacta gcaaaaatcg ccttcaatta ttagatgaat tggctcaaca
    18961 caagcgcttc aaaaattgca aactctccca ttttatcaac gacatcgacc ctgaactgca
    19021 aaagcaattt gcggctatga cttatcgtgt cagcctcgat acctatctga ttgtctttcg
    19081 tgggacagat gacagtatca ttggctggaa ggaagatttc cacctgacct atatgaagga
    19141 aattcctgct caaaagcacg cccttcgcta tttaaagaac ttttttgctc atcatcctaa
    19201 gcaaaaggtt attctggccg ggcattccaa gggaggaaat ctcgctatct atgctgctag
    19261 ccaaattgag caaagtttgc aaaatcagat cacagcagtt tatacatttg atgcacctgg
    19321 tctccatcaa gaattgacac agactgcggg ttatcaaagg ataatggata gaagcaagat
    19381 attcattcca caaggttcca ttatcggtat gatgctggaa attcctgctc accaaatcat
    19441 cgttcagagt actgccctgg gtggcatcgc ccagcacgat acctttagtt ggcagattga
    19501 ggacaagcac ttcgtccaac tggataagac caacagtgat agccagcaag tagacacaac
    19561 ctttaaagaa tgggtggcca cagtccctga cgaagaactt cagctctact tcgacctctt
    19621 ctttggcact attcttgagg ctggtattag ctctatcaat gacttggctt ccttaaaggc
    19681 gcttgaatac attcatcatc tctttgtcca agctcaatcc ctcactccag aagaaagaga
    19741 aaccttgggt cgccttaccc agttattgat tgatactcgt taccaggcat ggaaaaatag
    19801 ataatactct tgaaaattaa atgtatacaa aacaaaagac ctagaataca tactttcatg
    19861 tgcattctaa gtctttttaa atagaatcta atagtcaata aaaatcaaat agcattgaaa
    19921 gataattggg cttggaacgt ccctctcgct tcaacaaaat gaccccatta tagattaaaa
    19981 agatgccact tagaaaaagc aaaaaaggaa gtaagacaaa ggcaaataca taaaaagcta
    20041 actgaacatt ctcgtatcca tttttataaa aaaggtagga tagataaaaa taacttgaaa
    20101 tgagggataa taaaaataat actggattcc acaaacttct attatccttc caaaatgaca
    20161 ctataaaggc taatacaatt cctataacga gatacatttc ttactccttt aatagctaca
    20221 ttttatcata attatccaaa gaaaaaagag ggcatttatc cctcttaatc cttcatctga
    20281 ctctctgcat cggccacgac tttttctaga ctgatttgac caagttctgc ctccatagtc
    20341 aactgaattc tctccaattt ttgatccaaa acatcatgaa tatgagctcc tacagggcaa
    20401 tttggattcg gattgtcatg gaaactgaag agttgacctg tcttaccaag acattcgacc
    20461 gcctgataaa catctaaaag actaatatcc ttaaggtcct tgacaatctc tgttccgccc
    20521 gttccacgcg ctactgaaat cagctctgcc ttcttcaact gggacaagat ctttctgata
    20581 atgacaggat tgaccccgac actagcagcc agaaaatcac tggtcacctt gctttccttc
    20641 ccctcgaggg caatgattat cagcatatga gtcgcaatgg taaatctact tggaatttgc
    20701 atcctcttct cctttttacg aggctaccct gcctctactc ttctttttct attattatac
    20761 cctttttagt tgtaatgtca atcgttacca cttttcaacc agtcgtctaa ctcccgatcg
    20821 cagccctctt tctgagccaa ttctctcaaa aattcctgat gatgagtatg gtggatccca
    20881 ttgaccagac tttcatagta aacctcaaaa taaggaagtc tcaggtcttt agccagctgc
    20941 aattcagctg ccacatcgta gtctacccgt cggaagtcca tatctaccag gcccttgtca
    21001 tcaaactcca aaatcatata ctgggcccgc aagtccttcc gtagctgagc gtccaaaaag
    21061 aaaggttggc caatcgaacc cggattgaca atcaattgcc caccagtccc gtaacgaagc
    21121 aactgctggt gaatatgtcc ataaacagca atatcacagg gaggatgagt caccaagcgg
    21181 tcaaactcct cttgtttgcc aatatgaatc aactctcgcc cccagttctt atcaggcaga
    21241 tgatggctaa ttcccaccgt caaatcccca aactgacgat gaatttgaag aggttgattg
    21301 tggagcactt caatttcttc tagggaaatt tcctctaaaa catactggca ctggcgcaag
    21361 agatagcgtt gactggggcg agtactatcc aattccttac ggacaccatg ccaaagactg
    21421 tcttcccagt ttcccaaaac tctagccgta atcggtagtt gatccaacaa gtccaaaatc
    21481 cttctacgcc ctgtccctgg catgagaata tctcccaaaa gccagtattc atccactcct
    21541 atctgccgag catctgccaa aacagcctcc aaggcggtgg tatttccatg aatatctgaa
    21601 agaagagcta ttttcgtcat atccatctcc tcgttttttc tcttgcaata agtataacat
    21661 aaaaagtcac agctagagaa atctagcttt ttttgatata ctagataaag atattagaca
    21721 agaggaaacg aatgacccca aacaaagaag actatctaaa atgtatttat gaaattggca
    21781 tagacctgca taagattacc aacaaggaaa ttgcggctcg catgcaagtc tctccccctg
    21841 ccgtaactga aatgatcaaa cgaatgaaaa gtgaaaatct catcctaaag gacaaggaat
    21901 gtggctatct actgactgac ctcggtctca aactggtctc tgagctctat cgtaagcacc
    21961 gcttgattga agtttttcta gttcatcatt tagactatac aagtgaccag attcacgagg
    22021 aagctgaggt cttggaacac actgtctctg acctgttcgt ggaaagacta gataaactgc
    22081 taggtttccc taaaacctgc ccccacggag gaactattcc tgccaaggga gaactcctcg
    22141 ttgaaatcaa taacctccca ctagctgata tcaaggaagc tggcgcctac cgcctgactc
    22201 gggtgcacga tagttttgac attctccatt atctggacaa gcactcactt cacatcggtg
    22261 accagctcca agtcaagcag tttgatggct tcagcaatac cttcactatc ctcagtaacg
    22321 acgaggattt acaagtgaat atggacattg caaaacaact ctatgtcgag aaaatcaact
    22381 aatttctcaa gtcccctacc aaccctgaaa gttttatttt cagggtttta tttctatcat
    22441 tttattttac tttcatttgg tggtagaata tttgaaaaaa atgggagagt atttgaaaaa
    22501 aagaaaggta gtttaaccta tgaaaaaatc actaaaaatt tttgctacat ctaaatgatt
    22561 tgacctcttc ggggttgctt tggtcgttgg gattgcgatt gcatctggtt atctcaactc
    22621 acgcctcgat aaatttgtag actggggact atggacagct cttgtaccct ttggattgat
    22681 ttccgtaacc aacgttggga tttccatgtt gtccactcgt ttcacgggga aattaagcaa
    22741 atggggaaat tactttggta ttgttaatac cattttgtcc ggtgctattg attatatcct
    22801 tagaaataag gcggccatca ttacctatcc cgtcacctta ctcatttata cctttgctat
    22861 aaagaaatgg aaagcttcgc aagaaggcag acccaaccaa atgagccaaa aacaggtaaa
    22921 attggcggcc atcatcattt ccatcatcgc cttcctcttt gcctttgtga ccaactatat
    22981 cggatatggg ggcaagatga atctccttgc ctacgtaaca actattgcct ttgcactgtc
    23041 cctcattgcc aatgctttga atgcattggc aatgagcgac agtggggctt ttggttgatt
    23101 tacaatttcg ttcagctgac aaaagctggt attcaaggaa acttcgccaa tatcggtaaa
    23161 tacatctttt atatcctcaa tgcaatcgga gctttatttg tctggaatga tgaagaagtt
    23221 agataataga aggaaactca aataaagaat actagccaac ttaagagaat ctcccctctg
    23281 ctatttttat cattttagtt gtaactccca ttcttttaga gtagaatgaa gttagataaa
    23341 agagggaggt cttgtcatga aaaaactcta tagaatccat tttatagcaa ttgcagttat
    23401 tgatttgcta ctatttgcat tttttatccc aaatcattca tacctctctc aactagatgt
    23461 aacttacaaa ac
//
LOCUS       DAVHSY010000028        23247 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.029, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000028 DAVHSY010000000
VERSION     DAVHSY010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23247
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.029"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..672
                     /locus_tag="VVR43_001399"
     CDS             <1..672
                     /locus_tag="VVR43_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU6149752.1"
                     /translation="RIYLELRNRAYLVNHKRVQGLMKVLNLQAKMRQKRKYSSHKGDV
                     GKKAENLIQGQFEGSKTMEKCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIAFNLSCS
                     PNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSQD
                     NGMMESFFGILKSEMFYGYEKTFKSLNQLEQAIVDYIDYYNNKRIKVKLKGLSLVQYR
                     TKSFG"
     gene            complement(788..1591)
                     /locus_tag="VVR43_001400"
     CDS             complement(788..1591)
                     /locus_tag="VVR43_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEU6149753.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLFSEKMYLDLDLDFS"
     gene            complement(2194..3573)
                     /locus_tag="VVR43_001401"
     CDS             complement(2194..3573)
                     /locus_tag="VVR43_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6149754.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNVKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFPRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWLDGDQNTNVSESNNLMNYLEN
                     GVVISDKIPESDNKNLDDIIKLITGCPIKFNVSGNKGQKNNIELIAKQRSFIDYWAKY
                     VSYLPFPTP"
     gene            complement(3624..3788)
                     /locus_tag="VVR43_001402"
     CDS             complement(3624..3788)
                     /locus_tag="VVR43_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEU6149755.1"
                     /translation="MGKIVAIDLFSGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDME"
     gene            complement(3869..6520)
                     /locus_tag="VVR43_001403"
     CDS             complement(3869..6520)
                     /locus_tag="VVR43_001403"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU6149756.1"
                     /translation="MSKELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVVHDNVTKVATGEAGNVTDRWILHNLNETIGKA
                     TANFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ECDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(6513..7091)
                     /locus_tag="VVR43_001404"
     CDS             complement(6513..7091)
                     /locus_tag="VVR43_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU6149757.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAETLQLNSQHQPNELNH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(7091..7651)
                     /locus_tag="VVR43_001405"
     CDS             complement(7091..7651)
                     /locus_tag="VVR43_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6149758.1"
                     /translation="MARTELPDKIETECLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYAFLKSEWEVI"
     gene            complement(7638..8087)
                     /locus_tag="VVR43_001406"
     CDS             complement(7638..8087)
                     /locus_tag="VVR43_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEU6149759.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVVPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(8500..8895)
                     /locus_tag="VVR43_001407"
     CDS             complement(8500..8895)
                     /locus_tag="VVR43_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU6149760.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(8991..9245)
                     /locus_tag="VVR43_001408"
     CDS             complement(8991..9245)
                     /locus_tag="VVR43_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU6149761.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(9255..10589)
                     /locus_tag="VVR43_001409"
     CDS             complement(9255..10589)
                     /locus_tag="VVR43_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU6149762.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(10589..10822)
                     /locus_tag="VVR43_001410"
     CDS             complement(10589..10822)
                     /locus_tag="VVR43_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU6149763.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            10853..10927
                     /locus_tag="VVR43_001411"
                     /pseudo
     CDS             10853..10927
                     /locus_tag="VVR43_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(11135..11287)
                     /locus_tag="VVR43_001412"
     CDS             complement(11135..11287)
                     /locus_tag="VVR43_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149764.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKIVFKILD
                     WLFKLI"
     gene            complement(11284..11466)
                     /locus_tag="VVR43_001413"
     CDS             complement(11284..11466)
                     /locus_tag="VVR43_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149765.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            complement(11468..12247)
                     /locus_tag="VVR43_001414"
     CDS             complement(11468..12247)
                     /locus_tag="VVR43_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149766.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGPTTLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEALWTSREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            complement(12526..12876)
                     /gene="rbfA"
                     /locus_tag="VVR43_001415"
     CDS             complement(12526..12876)
                     /gene="rbfA"
                     /locus_tag="VVR43_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU6149767.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(13127..15919)
                     /gene="infB"
                     /locus_tag="VVR43_001416"
     CDS             complement(13127..15919)
                     /gene="infB"
                     /locus_tag="VVR43_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU6149768.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            complement(15936..16235)
                     /locus_tag="VVR43_001417"
     CDS             complement(15936..16235)
                     /locus_tag="VVR43_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU6149769.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(16228..16521)
                     /locus_tag="VVR43_001418"
     CDS             complement(16228..16521)
                     /locus_tag="VVR43_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU6149770.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(16543..17679)
                     /gene="nusA"
                     /locus_tag="VVR43_001419"
     CDS             complement(16543..17679)
                     /gene="nusA"
                     /locus_tag="VVR43_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU6149771.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(17723..18202)
                     /gene="rimP"
                     /locus_tag="VVR43_001420"
     CDS             complement(17723..18202)
                     /gene="rimP"
                     /locus_tag="VVR43_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU6149772.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            complement(18328..18963)
                     /gene="trmB"
                     /locus_tag="VVR43_001421"
     CDS             complement(18328..18963)
                     /gene="trmB"
                     /locus_tag="VVR43_001421"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU6149773.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(18960..19754)
                     /locus_tag="VVR43_001422"
     CDS             complement(18960..19754)
                     /locus_tag="VVR43_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU6149774.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(19915..20526)
                     /locus_tag="VVR43_001423"
     CDS             complement(19915..20526)
                     /locus_tag="VVR43_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6149775.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            complement(20677..20910)
                     /locus_tag="VVR43_001424"
     CDS             complement(20677..20910)
                     /locus_tag="VVR43_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149776.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(20952..21641)
                     /locus_tag="VVR43_001425"
     CDS             complement(20952..21641)
                     /locus_tag="VVR43_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6149777.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYVTLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFLSLPSLLDIFVFATFGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            complement(21673..21906)
                     /locus_tag="VVR43_001426"
     CDS             complement(21673..21906)
                     /locus_tag="VVR43_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEU6149778.1"
                     /translation="MDTKMMSQFAVMDNEMLARIEGGDVSDIYRGYANQVSPFGSYPP
                     ILKNSGPFPVSGYCPRGYHDRGYIGAGFHLCGI"
     gene            complement(22150..22383)
                     /locus_tag="VVR43_001427"
     CDS             complement(22150..22383)
                     /locus_tag="VVR43_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEU6149779.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGCAAG
                     GVKYGRLLGPWGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(22533..23247)
                     /locus_tag="VVR43_001428"
                     /pseudo
     CDS             complement(22533..23247)
                     /locus_tag="VVR43_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS5 family transposase"
BASE COUNT         6700 a         5104 c         4236 g         7207 t
ORIGIN      
        1 cggatttatt tagaactaag aaatcgtgct tatctggtaa atcataaaag agttcaaggc
       61 ttgatgaaag tactcaattt acaagctaaa atgcgacaga aacgaaaata ttcttctcat
      121 aaaggagacg ttggcaagaa ggcagagaat ctcattcaag gccaatttga aggctctaaa
      181 acaatggaaa agtgctatac agatgtgaca gaatttgcca ttccagcaag tactcaaaag
      241 ctttacttat caccagtttt agatggcttt aacagcgaaa ttattgcttt taatctttct
      301 tgttcgccta atttagaaca agtacaaaca atgttggaac aggcattcac agagaagcac
      361 tacgaaaata cgattctcca tagtgaccaa ggctggcaat accaacacga ttcttatcat
      421 cagtttcttg agggtaaggg aattcaagca tccatgtcac gtaagggaaa cagccaagac
      481 aacggtatga tggagtcctt ctttgggatt ctgaaatcgg aaatgtttta tggctatgag
      541 aaaacattta aatcacttaa tcaattggaa caagctattg tagactatat tgattactac
      601 aacaataaac gaattaaggt aaaactaaaa ggacttagcc ttgtgcaata cagaactaaa
      661 tccttcggat aaattatttg tctaactttt tggggtcagt acacctaaaa ctttgatgat
      721 atacgttttc ttgtgagaat atttacttca tttttgccta aaattcaatg tttactcagt
      781 atttggatta tgaaaaatcg aggtctaaat ctagatacat tttttctgaa aacaaatcat
      841 tttgaccacc gagcaagaga ttttcaaaaa aagctgttaa aaactcagaa cgtcgctgta
      901 aaatctttgc attatctaat accaaggcat cacgaaaata tttggaatgt tgctgaaatg
      961 gtgtattatc aatatcaaaa ccaaactcac gaagatactg aatcaaaaag accgttactg
     1021 tccgagtgtt tccttcgcga aatggatgaa tctgccagat tcctgaaata aaatgctgga
     1081 tttgtttaac cacatccgcc tgagttagtg tcgcatatgc aacttgtttt tcctgattaa
     1141 aatcataatc taaggtcatt tgaatcatgg agtaatcaga gtacacaaca ctttcaccat
     1201 tcaaaacagg ttcattcttt gtgatattgg tctgacgaaa ttgccccacc ggaatagagg
     1261 gttcaaatat atcttgaaac aactccttat gaatagcaag taaggtcgca ggactaaagc
     1321 taaagcctct tcgagacaat agttctacaa tgcgtagaga aaccaagtct gcctcttccg
     1381 tacttgcatc aatagtatgg tgataagccg ttgcatcctc ataaacctgc tcataagtca
     1441 gttctccccg ggactgtttc tcagccaaag attccatata cgctgatggc actagattgt
     1501 caactttctg cagaccaaaa cctatccgcc ataaatcacg cttcgcttca taagacaagt
     1561 ttggattgtc aatgttgtaa gttgattgca tagaaatatc ctttcaattg tttttctgtg
     1621 tcatcggtaa attgtgaaat aggtatggaa ttggcgaaaa ttataaaaat ccttcacaat
     1681 aggttctatg aaatatatat acttcatctt aatagtgagc aagctaaact tagcatttca
     1741 tgccctcata tgggatgttc tttaactaaa taatatgatt atcgagatat atctggataa
     1801 atgaactaat aagtctgacg cgtagactta tcaaagtcat tggcatacac cactatgaac
     1861 tcgttgatct gttcaaatcc caacacatta cctgagaaga aagttgcaat gttgtttttg
     1921 gtgcgggttt gaatttaaaa atttgttatg tagtacctaa tctaaggaat tagaacaatg
     1981 cctctaattt ttctttaata cactgaaaca ttgatgattc tggctgtatt tttgaaacag
     2041 ctcttctttg ctcctggaaa atatcttcag aagttatatt ctctattcct aacgctactt
     2101 gaattttttt ctaaaatatt cttttccgtt gccatcttta gaaaaatcat aaccttccct
     2161 atctacgctg ttacataaat tagctaaaaa aaactatggg gttgggaaag gaagataaga
     2221 aacgtattta gcccaataat ctataaagct tctttgtttc gcaattaatt caatattatt
     2281 tttttgccct ttattacctg aaacattaaa tttaattgga catcccgtta tcaattttat
     2341 aatatcatca agatttttat tatctgattc aggaatttta tctgatataa caacaccatt
     2401 ttcaagatag ttcattaaat tatttgattc actaacatta gtgttttgat ctccatcaag
     2461 ccaaaaataa tggttatcgg aatctaaata cgatgagttt aaaatattat tacaaattat
     2521 ttgatttgct ccaccaggga tatatctcac tactaaattc tgtttaagat tctcactacc
     2581 tgaatgagtg ataacaaact ctagaatata tttagctagt ctatcttcaa cataaatcat
     2641 cttcctagaa tgatacacat cacctaattc aaaaaatgca tcctgataat caatattttc
     2701 aataacatct accttttctc cgtttttcac taaaagtttc acggcttctc taggaaaatc
     2761 ttttataagt tgtgtagaat gtgtagtgat aataatttga tgttttttat ttaaacactc
     2821 ttgaagtaaa aactctttaa atttatagat tgcactcgga tgaagtgaga tttcaggttc
     2881 atctattaat attaatgaat ttgattgcgc atttactata tcatttacta acaaaataat
     2941 tctagcctca cctgttcctg caaaagcctc agaatattct tttccagatt ttttcatcca
     3001 aatagttttg gaagctttta tatcatcacc ttttgaatac aacttatgtg ttaaaatttg
     3061 aatgtctgta taagattcat ccattatttc actaataatt tcacaaactt tatcatcaac
     3121 tttaacatta tctataacca tttccttttt ataacgcgta tagctacttg tattattctt
     3181 taaaatatca gcaactggtt tagatcgtaa tcttataaaa tcttgtttac tacgttgagt
     3241 agaaattttt ttaaaattat agtgatagaa aaataaatca aaagcagaaa catattcttt
     3301 acaatcacaa aagacaacat ttttttcaat gccatcccat ctgtctgtcg aagaacttcc
     3361 aatatattta tttttgggta atctttccat ctcatattgt ttttgaggag catatggttc
     3421 ccaataatct aatccttttt ttgttccaga acggccttta agaacttcta catttctaga
     3481 agctttaacg ttataatatg aatagattaa acattgtttc ccatccactt catctatttg
     3541 atcaacattt gtactaaacc aatattcaga cacactttta ttggctggag aaccatataa
     3601 agcttgtaaa attgaagttt tatttactcc atatctatta cagacacctc aggattattt
     3661 aacttataag ttttaacagc tacggaatca atttcaacag caacttgaac atctatgcct
     3721 gattttttaa ggccacttgt agtgccacct gcaccgctaa ataaatcaat agcaacaatt
     3781 ttccccatag tattctccta aagtttctcc tttttattat aacattatca aatgtaaaac
     3841 ccaacccgag agggttaggt ttttaacatc atttcaccaa cttcttcatc tcatcaatac
     3901 gtgcgacggt cgcgtcatat ttagcttggt agtcagcttg tttgtcgcat tctttttgga
     3961 cgacttctgg tttggcgttg gctacgaagc gttcgttaga gagtttctta ccaaccatgt
     4021 ccagttcttt ttgccattta gcaagttcct tgtcgagacg ggccagttct tcttcaacat
     4081 tgaggagatc ggccagtggc aggtagattt ctgctcctgt gatgacactt gacatagcca
     4141 gttcaggtgc agggatggtt gatgcgattt ccaaatgttc tggatttgta aagcgtttga
     4201 tgtagttgac attgctgtta aagaaggctt ccaagtcgct atcgcttgtc ttaacaagga
     4261 tggtgatagg tttgcttggt gctacattta cttccgcacg cgcattacga acggcacgga
     4321 tcaagtcttt gagactttcc acaccagtgt gggcagcaag gtcctcaaag gctgggttga
     4381 cagttgggta tgctgctgtc acgatagagc cttcagcgta ctgaccaaag atttcttctg
     4441 tcacgaatgg catgattggg tgaagaagac ggaggatttt atccagcgta tagaggagaa
     4501 cagatcgagt aatgacctta tcgtcttcat tgtcgctgta aagaacttcc ttggtcaact
     4561 caacatacca gttggcaaat tcttcccaaa tgaagttgta gaggatgtgg ccagcaacac
     4621 caaactcaaa cttatcaaag ttagcagttg cttttccaat cgtttcattg aggttgtgga
     4681 gaatccagcg gtccgtcaca ttaccagcct cacctgttgc aacttttgtg acattgtcat
     4741 gcaccacatc cagcgtcaaa ccttcattgt tcataaggat gtagcgagag atgttccaga
     4801 tcttgttaat gaagttccat gaagcatcca ttttctcata agagaaacgc acgtcttgtc
     4861 ctggcgcaga accgtttgaa aggaaccatc gaagggcatc ggcaccgtat ttctcgataa
     4921 catccattgg gtcaatcccg ttaccgagag acttagacat cttgcgtcct tgctcgtcac
     4981 gaataagacc gtggataagg acgttttgga atggttgacg gcctgtgaat tccaatgact
     5041 ggaagatcat acgagacacc cagaagaaga tgatgtcgta acctgttacc aaggttgaag
     5101 ttgggaaata acgtttaaag tcttctgagt cgacttcagg ccagcccatg gttgaaaatg
     5161 gccagagggc agaactgaac caagtatcca agacgtcttc gtcctgagtc catccgtcac
     5221 cttctggagc ttcttcgccg acatacattt caccatcagc attgtaccag gcagggattt
     5281 ggtgacccca ccaaagctga cgagagataa cccagtcgtg gacattttcc atccattgaa
     5341 ggaaggtatc gttgaaacga ggtgggtaga attcgacctt gtcctctgtg tcttggttgg
     5401 caatggcgtt cttagccaat tggtccatct tgacgaacca ttgagtagac aagcgtggct
     5461 caactacgac acctgtccgt tctgagtgac cgactgaatg gacacgtttt tcgattttga
     5521 caagggcacc gatttcttcc aacttagcaa cgactgcctt acgagcttca aaacgatcca
     5581 tgcctgaaaa ttcaaaggca agctcattca tagttccgtc gtcgttcatg acgttgactt
     5641 gtggcaagtt atgacgttgg ccaaccaaga agtcatttgg atcgtgggca ggtgtgattt
     5701 tcacgacacc agtaccaaac tcaggatctg cgtgctcatc tccaacgatt gggatgagtt
     5761 tattagcgat tggaaggatg acgtttttac caatcaagtc cttgtagcgc gggtcttctg
     5821 gattaaccgc aaccgcaacg tccccaaaca tagtctcagg acgagttgta gcaacttcaa
     5881 gggcgcgtga accatcttcc agcatgtaat tcatgtggta gaaggcacct tccacatcct
     5941 tgtgaatcac ctcaatatca gaaagggctg tgcgagctgc tgggtcccag ttgatgataa
     6001 actcaccacg gtagatccag cctttcttgt aaaggtccac aaagacctta cgaacagctt
     6061 ttgacaaacc ttcgtcaaga gtgaaacgct cacgagaata gtctacagag agccccatct
     6121 tgccccattg ttccttgatg gtagtggcat attcgtcttt ccattcccag actttcgtca
     6181 agaaagactc acgaccaagg tcatagcggg aaatgccctc accacgcaag cgctcctcaa
     6241 ccttagcctg agtcgcaata ccagcgtggt ccattcctgg aagccaaagg gtatcaaaac
     6301 cttgcatgcg tttttgacgg atgataatat cttgcaaagt tgtatcccaa gcgtgaccaa
     6361 ggtgaagttt acctgtaacg tttggtggtg gaataacgat tgaataaggc ttagcctttt
     6421 gatcgcctga aggcttgaaa acatcagcat caagccattt ttgataacga ccagcctcaa
     6481 cctcggctgg attgtattta ggtgaaagtt ctttagacat gtgtgtgtcc tttctctatt
     6541 ttgtttattt tattttgaat ttgcttagca gcttcttctg cagacaaatt cgtattattt
     6601 attttaaagt agtggttcaa ctcattcggt tgatgttggg aatttaattg aagtgtttca
     6661 gcggtctcta taatttctct ttcagatacc tcaatatgtc gttttaaggg tttgtacttt
     6721 aatcgattct ccgttcgatt tcgacgtatg cactcttcaa gacttgtttc caactcaaca
     6781 aaaagaatct cttgatgata atcatccaac aaactctgaa tttgctttaa atatatcaga
     6841 tgatactgat ttgaaaaatc aattacatct gttaaaatta ctgatcgctg atttcttgca
     6901 ctcgctccaa ggaatgaaaa agtgattcca cgaacaaatt cccacatttc ctctgtatag
     6961 tcctgataga tttctagtgc aaaatcaatg gcttgatggt tataaaagag ggtagcatcc
     7021 gtcagtcgag ataattcttg accaatggtc atttttcctg atgctggagc accaatgatg
     7081 aaaagatgca tcaaatcacc tcccactcac tcttcagaaa ggcatatctc aaatcatcac
     7141 agcagttgcc ttgagcatct ttgcggtctc ttatgcgagc ttcgagggta aagccaagtt
     7201 tttccgcgac tcgttgactt tgaaggttat atccaaagca agttagttca atcttgtgaa
     7261 gacccaaatc tttaaaggct aagtcaatca aggcacgcgc agcttctggc acataacctc
     7321 gcccccaata gtctgggtgt aaggtatagc cgatttccag cacatcatct tcatggcgat
     7381 ggttgaaatc gacagagcca acgatcttat ccgttccttt gacgacaatc ccgtagcctg
     7441 ctgggagatt ttccttttga ttacgctccg gaagaatgtg ctccagataa taaatctcat
     7501 cttccaaggt cttgactgga ggaaaacctg ctggataggc gacctctggc aaactagcat
     7561 agtcaaagat atcctcagca tccgccacag tacggactcg taaaacgaga cattctgttt
     7621 cgattttatc tggtagctca gttcttgcca tccttcttcc tcgctttttt gatgaaactg
     7681 cccttcatat ctacacgctt gtccagatag cgataaacgc gctgatatcc atctcccatg
     7741 aaataggttg gggcaaacag ttgattttta aaatgtccct tttcatccag gagttctgga
     7801 acaacaagtc gctcaagaat cttggcaaag atgtggcaaa taccgtcttc ctcaacaatc
     7861 ctatctaccc gacaatctaa aacaagtgga caggcgtcta aaataggagt ctgagttcgt
     7921 tcagaaattt cataatgcac tcccaaacgt tccaatttct cctgatgact gataaaacca
     7981 gcctgctcca tcgcaagcat agaagtttca tcagaaatat tcacagtaaa tttttgatac
     8041 tgtttgatct gctctgcggc attctctctc gcaacgactc caatcacaac ccaatctcct
     8101 agactataag aggaactaca ggtcgtgatg ttatagccaa aattctaatc ttgatatcct
     8161 aaaataaaaa caggaaaacc ataatatagt ttacttgtgt taaaagattg cttcataaca
     8221 accccctttg actaagacgt aaaagaaaag ccctgccatc tacatgacag ggacgaatgt
     8281 gtttatccgc ggtaccaccc aatttcgggc agttgcccgc aactctcgtc tttaaagcaa
     8341 aaagacactt ttatttcaat ttttcatcca ttagcaacca gttttgacac atttgtggac
     8401 ttctcagcgc cgccactttc tgtaaaatgt gggattcaaa acacctctaa tggctctatt
     8461 gtagcaagat tttttcggaa atgcaaggct caagaaaaat tacttgaact tgatgccatt
     8521 ttctttcaat ttcttgatgg tagctgggcc gattcctttc aaggcaagga gttctttttc
     8581 agtccagttt ttgaaatctg aagcagactt gattccttca tcatagaaag tcttggcacg
     8641 atcaagtgga agtccaccca aatttgctgc aaaatcttct acagaattag ctactttttg
     8701 agcttgctct ttggtagctt ctactgcttg ttcaactttt ttagaaacag ccttaccagc
     8761 tgcgcttgct gactgttctg cacgcttcac gacttttttt gtctcatcta caaccttagt
     8821 cacagtactt gaaaaggcac ctgcgcgacg gaggccattt cgtaattgtt ttttacgatt
     8881 gagtttcttt gacatgataa aatcctttca ataaaaaatc cctgctctga caaggattta
     8941 acataaacat tctatcaaga ttttagtgaa aaatcaagaa tctttctcgt ttaataattt
     9001 cgctcaccaa acaagccttc tggcaaatca tggaatccct tgcctgcttt gaagttttca
     9061 aacttaccaa gcaagaactg ataagcatcc aagcgactct cgtagcgaat catggcatct
     9121 ttggcacgct cgtcctggtc ttcttcgtaa actttttgac tttccttgtg cgccatatcg
     9181 ttaatcatga tttgggtatt gacccaagct tcaaattcct tcataaattc ttgttcgtaa
     9241 ctcatttttt ctccttattc taatccacga aaatagtccg tatcaatctc acggtagggc
     9301 tggatatcct gaacatactc caacactcct tggaattctc cgtcttcatc gtgtactgca
     9361 gcataggtga tgtggacaaa cttacctcgc gactcagact tgaaccacat ttcatacttg
     9421 tctttgcttc cctcacgaag ccccttcatg atagttttga ccttgtccaa gtacttaggc
     9481 ggatggcaga gttcgacatt gcgcccgact tgggacggcg tccgtttgaa aatcatctca
     9541 tcagctggcg tattgtcatt gtaatactgg aaaatatctt ctttattgac aaaggtaatc
     9601 tccataggga gatgattgag gatgagattg gcctgctcga ctgaaagata gccattacca
     9661 aaagcctgtt gactatggcg gtccagcaca gcttcctttt ccttaggggt aaaggtaatg
     9721 gtaaaatggc cttctggcgt atctatgact tgttgaactt gaccttctgc cgtatctagc
     9781 tgtacaggtt cctctgcaat cttttcctca ataaagctct gtcgttctgg cacccatttc
     9841 tctgacggac ggatgatggc atagccatag gcatcgctct cctccgcaat ctgaagccag
     9901 tcatcctgag taaaagactc aaggagaatc atgaggagga tggactcttc cttgaaaatc
     9961 atactttcaa actctgtcgc aaaagcttca aaagcttcct ttacactgct aattgacact
    10021 tctggtagtg acttggctgt cgttagagct gtttgaaaga gttccctaat ctgatcatcc
    10081 actccccaca taactttggg aggtgaatcg tgtccatagc gctccatgat aggaaagaag
    10141 agttcttcct tacgttggta atggatgtca aattgcccca caagccccat ctgacgcacc
    10201 aagcccttgc gcatctccgc aagcatttcc tcgtcttcca tcaactcata ggtatctaac
    10261 aatctacgaa tgcgaatcaa agctgcacgg agagccagat tttcttcttt gaagacacga
    10321 actgggtgac ctggatgctc agtatctgaa acttcgacac ctttgatagc atttttaaaa
    10381 agattggcat ggacatcaca gagttccata acatcttcaa aagtgacgcc cgaatccgag
    10441 ttcatcagct cgtgctccat aagggaaatc tcgatggctg acacgcccgt aaaggtcgca
    10501 tcaaagcgat cttgaaccga ctcaggagag gcgccattgt gcaattctaa caaaatatcc
    10561 cgtaggacat gaatccgttc atctgccatt agtctaatcc aatcacttcg tagccattcg
    10621 cttccagtgt gcgtacaatc ttgtccatag gagttcctgc tagcttagaa ccctgtttaa
    10681 gtgatacttt acgaccaact gtattgcgca ttaagggatt ggcaaggggt ttaaaaccca
    10741 actccactag aatttccaag acttctggat gcttgtccac cacttctgca acaggaattg
    10801 acacatcgat gatattgtcc atgacgacct ccattgtatg ttctaatact caatgaaaat
    10861 caaagagcaa actaggaagc tagccgcagg ttgctcaaaa cagtgctttg aggttgtaga
    10921 tagaactgac gaagtcagct caaaacaccg ttttgaggtt gtggatagaa ctgacgaagt
    10981 cagtaacata tatactgcaa ggtgaagctg acgtggtttg aagagatttt cgaagagtat
    11041 aaaatgattt tactgcttat attataccat atggaaagag aataaaaaac tagcagtgga
    11101 gttcctgcta gttctctgcg acttggatta ccatctagat aagtttaaag agccaatcca
    11161 atatcttaaa cactatcttg taaaacagca attggactgc aaaagagatg atcatccaaa
    11221 agaatttcac aatcccaata atcggtttga taaaaataat ggcaagaagt ccccagaaaa
    11281 atttcatttt ttatcctctg gcttaatgag ccaccgagcc gtatccatta gcttatctgc
    11341 aataaagagt tttcccagac caacaacgac atggtcatct ttctttatcg ttttcattac
    11401 ttttacacct tgcacggtca aaaagtaatt accataaatt ttagctagag tttttatgag
    11461 tcccatatta ctctccttcg atgatttcag cctcttttcg gattgtttca acatcttctt
    11521 gatattgaac ttcactatag ttaactagct tggacaattc tttctgcaag ctttcaccca
    11581 tcggtttcat agttgcaaag gttaaaccac ctgaaatgat accacccaag ataggaataa
    11641 atttccccat tcctttggcc agccctccct tggtaagatt cacaccaaat attcttaaga
    11701 cttttttcaa aataggatac caaagcgtct ttgttaaagc tttattaggt actgttttca
    11761 ttacctgttt ggcaattgtt ataccaccag cacgtagcaa agcagcagtt ccattcaccc
    11821 ccaacatgac gcctagataa agcaagaggg tattttgagc atcttcactt aactcctcac
    11881 gtgaagtcca aagagcctca taaccataaa tataacctaa ttcttgagcc aatttcagag
    11941 agaaagcata aaattgagcc acatcagctg gaatggtaat tgccatagca agccctccag
    12001 gtaatcctgc caaaacagaa gtcccactcg ctaataatac attgtcccga atacaagcat
    12061 tagctacacg atctaatatt tcttgagata gaagagtcgt tggaccttgt tccaataagg
    12121 taggaatatc ttttggatcc aattctttgg aaaacttatc cactaaaaat ttcgaacgat
    12181 caaccttaac aacaggtagt ttcaccactt gttgcaatac ttgcatagct aagtcttgtt
    12241 cagccatata caaactcctt atttcttttt tgcaccttat catattatat ttcctacaaa
    12301 aaaagcattt tctaattaga taacattaaa aaatacagaa cccctttttt atattaaaat
    12361 gaaacaagaa caggacaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    12421 agtagaggtg tactattcta gtttcaatct attataaaag aatatttttc catttcaaat
    12481 tcaacctatt ttcctccacc aaaaaagagg ggcaacccct cttctttagt tcttatccag
    12541 attgcgtagc atctcgtcaa tcttgtttcc atactcgatg gactcgtctt tgacgaaggt
    12601 caaatctggg attttgtaca atttcaaatt gcgaccaagt tcacgtttga tggtaccagt
    12661 tgctttttca agcccgattt gggctttttg gttatccgaa gcaaggttac tcaaaatggt
    12721 gtaataaacc ttggcaacag acaagtcacc cagcatctga acatctgtga tggtcacacc
    12781 ttggacacgt ggatcacgga ctttcttttg caaaatctca ttgacttcac gcttgatttc
    12841 catgcccaca cgatctgtac ggaaatgatt tgccatgata ttcctttctc tactttgaac
    12901 caaaagctag gccagcagac ctagctattt taaacttctt gattttcagt ttaaattgaa
    12961 acgaagttca atttgaagtc atctgcttct ttcgccgtgg tgaaagtgat ggaactgatt
    13021 tatcagtccc atcacagggg atttttgaga ccctaggctc aaaaataagc aatgaaacca
    13081 tcggtttgct tgcgtccctc accacctaag aaaggagcaa aaaatcttat ctcttgattt
    13141 cttccatgac atacgcctca atcacatcat ccatcttaat atcattgtag ccgtcgatca
    13201 tcaatccacc ttcacgaccg tttgtcactt ctttcacgtc gtctttatag tgtttcaagc
    13261 ttgcgagttc accatcatag ataacgacac catcacggat aacacggact ttagagtcac
    13321 gggcaacctt accgttgata accataaatc caccgatagt tcccacttta gacaccttga
    13381 aggtttcacg gataaccgct tcaccaataa ctttttcttc aaattctgga tcaagcatcc
    13441 ctttcatagc ttcttccatc tcttcgataa ccttgtagat aatgctgtga agacggattt
    13501 ccacatcgtc agcttctgct tgttgacgag cttgtggtgt agggcgtacg ttgaaaccaa
    13561 cgataaaggc atttgaagct tcggcaaggg tcacgtctga ttcgttgata gcaccgaccg
    13621 ctgagtggac gatagtcact ttgacacctt ccacgtcaat cttttgaagt gaggcagaaa
    13681 gggcttcaac agaaccttgt acatcagcct tgatgataac attaacagat ttgagttccc
    13741 cagctttaag ggtatcaaag aggttttcaa ggctaacacg ttgggtagct tgacgttgtt
    13801 tcatgagggc acgtttggca cgctcttcac ctgctgcacg cgcagatttt tcatcctcgt
    13861 aaacggcaaa gtggtcaccc gccatcggtg cttcgttcaa acctgtgata gagactggtg
    13921 ttgatggtcc agcaacttta acacgacgac caaggtcgtt ggtcatagca cggacacgac
    13981 cgaaggtatt tccgacaacg attgggtctt gaacattcaa ggtaccttgt tgtacaagaa
    14041 gggttgcgac cgcacctttt cctttatcca agcgcgcttc gataaccgta ccgattgcac
    14101 gcactgttgg gtctgccttg agttcttgga tttcagctac aagaaggact gtttccaaca
    14161 attcttcgat attttggttg aatttagctg agatttcaac aaattcagaa tctccacccc
    14221 aagcggttga cataactcca tgctctgcca attcaccgat aacgcgttct gggttagcac
    14281 ctggtttatc aatcttgtta atggctacga tgattggaac gttggccgct tttgagtggt
    14341 taatggcttc gatagtctga ggcataaccc cgtcatctgc cgctacgacc aagatcgtaa
    14401 tatcggtaac agaagcacca cgcgcacgca ttgatgtaaa ggccgcgtgt cctggtgtat
    14461 caaggaaggt aatcttctta ccattttcca cgatttggta ggcaccgata tgctgagtaa
    14521 taccacctgc ttcacctgtc gcaacacgtg agttacgaag agtatccaaa agggttgttt
    14581 taccgtggtc aacgtgtccc atgatagtaa caactggtgg acgctcaacc aattcatctt
    14641 cattgagata accatcttcg acaaagaaac gttcgatgtc agcattatcc acttcaacct
    14701 tttgtttggc ttcgataccg taatccacca tgaggagttc aattgtttcc ccatctaagg
    14761 attggttttg tgtggccatg acacccatca tgaaaagttt cttaacgatt tcagctggtt
    14821 cacgtttgat acgttttgcg atttccgcaa cggtcatacc atctgtatat tcaaattctg
    14881 ttggcaattc atggaattta cgctccgtaa caggttttgg agtctgatta cggttgttct
    14941 tgttattgcc ttttttgttc tttttgttgt tattccagtt actattcttt tgatttctca
    15001 cttgattttg actacttcga ttcttttgtt gttttctagg accatcttct tcatgatcat
    15061 aatcgtcacg atttttgtct ggtcgagctt gttttttacg acgtgtatcc actgcaggtt
    15121 cttttttctc agggacgact tcaaccactg cttgaacttg ctgtgcttgt tcagctaact
    15181 tagccgcttc ttcaaagatt tcctctggtt ccttgcgttt gttagcttga gccaaggctt
    15241 ctttagcagc ctgatactgc ttgaagcgtt cctcacttga acgagcgtac tctgcatttt
    15301 gctctgcttt tagggctgct gcacgggctt taaagtcaat acgtggagcc gcttgatttg
    15361 aacgtttatc ctcttgctga cggcgctcat ttctacgttt ttgctgacct tgctgcttct
    15421 tagcttggtc attaaagcga cgattgtcgc ggttgctttg accttgtttt ccaccattac
    15481 ggccgtcgtt tttctgacgg tttccgtttt gttgttggtc acggttattg cccttatttt
    15541 gcttgcgtcg ttctgcctgc tctttagcac gggcttcacg ctcagccttg aaattacggc
    15601 tttgcggttt cgctgctact ttttctgttt tcggagcaac tggctcagcc ggttttgcct
    15661 cttccttagc tacagctggt ttagctggct cagatttttc ggctttcttt tctgcactta
    15721 cttttggtgc tgcaggtttt gcttctactt tcggagcagc tgcaggctta aagctggcag
    15781 caatttttgc agcgacagct tcttccacac ttgatgagtg gcttttcaca tccaagccca
    15841 actcttttgc acgcgctaca acttctttac tttcttttcc aagttctttt gcgatttcgt
    15901 acaatctttt cttagacaaa tcatgtcctc ctcttctatt ccataagaga cctcattttc
    15961 tttgtaaatc cagcatctgt tacagccaaa acctttctcg atttcccgac tgctatgctt
    16021 aattccagtg ttgaaaacac ggttacaatt tctacttgat aataatgact tttatcttga
    16081 atcttcttgg tcagattggg tccagcatca tgagctagaa agaccaactt ggccttgccg
    16141 tcttgaatgg ccttgaccac caattcttca cccgatatga tgcgccctgc tcgctgagca
    16201 agccccaaga gattacttat cttttgctta ttcaagtccc aactctcttc ttttcacttt
    16261 gtgatccaca taagcgatca actcgtcata aaagctttct tccacttcca tgctaaagct
    16321 gcggttaaag accttcttct ttttcgcctc tagggcttct gcattgtcta gtttgatata
    16381 agcgccgcgg ccattggcct tgcccgtagg atcaataaag acttgtcctt ccttgttctt
    16441 gacaatgcgg agcaaatcac gcttatcaat cacttcgtta gacacaacag acttgcgcaa
    16501 agggattttt cttgttttca tctttccctc ctctagcagc ttttattctt ctacagtatc
    16561 gttttctact tccaactcta ctgaagcagc gtcttccatg gcttcaaatt cgctagcaga
    16621 cttgatatcg atacggtaac cagtcaagtg agccgccaag cgcacgtttt gtccacgacg
    16681 accaatggca agagaaagct tgttatctgg aacaaccacc aaggcacgtt tgctgtcgtt
    16741 ttcatcaaag ataacttggt caacctcagc aggagcgatg gcattgtaga taaattcagc
    16801 tggatctgct acccactcga taacatcgat attttcttcg attggtacca tgcggtcatt
    16861 tttagcatcg taacgagctg ggtggaattt gctagtaatc ttcttgatat tagcaccacc
    16921 acgtccaacg attgtaccga tagcatccac gtttggattg tggctacgaa cagcaacctt
    16981 cgtacggtca cctgcttcac gagccacgct catgatttca acagttccat cataaacttc
    17041 tggaatttct tgctccatca aacgtttgat catttctgga tggctacggc taacaaagac
    17101 gttcacacca cgagggttgt cttcaacctt gtaaacataa acttcgatac gatcatgaga
    17161 agcaaaaact tctccaggaa tttggtcttg ttttgacaat tgggcttcga tgctaccaag
    17221 gttgacatag ataaagcgat tgtcaaagcg ttctactgta ccagacatga tttcttgctc
    17281 atgttctttg taagtattgt aagtgatggc acgtgtttgc ttgcgcattt tttccatgat
    17341 ggtttgtttg gcagattggg ctgctacacg accaaactca gctggtgctt cttcaaactt
    17401 gattttgtct ccaagttcat aagctgaatt aatggcaaga gcatctttca agctgatttc
    17461 caaacggcta tcaaatactt catcaacaac ttcacggaca gtataaactg taaagtcacc
    17521 tgttttttcg ttgaagtcaa tagctacgct gtctgactga ccatagcgtc tgcgataagc
    17581 ggaacgaagc gactctacta ctgcgtcgat gatatcttct tttttgattc ccttgtcttc
    17641 ttccaaaatg cggaaggcct ctagcatttc tttactcatg ttttcttcac ttttgaatcc
    17701 tcaaaagcta tcctttcttt ttctataatt taactgctaa acgtgctttt gatactaaac
    17761 tgtatggaat ttggacggtt ttcttacgcg tcttgtccat atattccata gtcaactcgt
    17821 cctcttcgaa ggccaacaag gttccttcaa agaccttttg cttatcgatg gcttggtaga
    17881 gcccgacatg gatgtatttt ccaaccgctc cagcgacggc atccttggtt ttcaaaggac
    17941 gttccaaacc tggactggta atttctagga aatattgttc tgggaaggga tctggcttga
    18001 tggtgtctag gacaggactg atcatttctg tcaagtctgc cgtgtcgttc aaggtaattc
    18061 cttcgggttt atctacaaaa atactgagaa tcatgtcact gccaatcttt ccatactcga
    18121 tatccacgag ttcaaaagga gcttctatga caggttctac aacttctctg actaattcta
    18181 cgattgttgc gattgcgtcc acctcctcat aagcaagagg cgaagatatt tccccgcctc
    18241 acttttcata ttcttactat cagtatagca cgtttgccaa cttatgtaaa gcaaaagcac
    18301 ttgtacagcc taattttagg ttatctctta aaattctgcc tcaactcggt agataacttg
    18361 ccccttgttt gagaattttt gctcgtattc tgtcatgaca ttgccttcaa aatcactggc
    18421 atgcaaatct aaccagacac cattgagttt catgccatat tgagaaaagc tcactaaact
    18481 gtactcaaac aagccacggt tatccgtctt gaaatgaatt tctccatttt caggcaagat
    18541 acgtttgaag gtatccaaga aggtcttgta ggtcaaacga cgcttttcat ggcgtttttt
    18601 cggccatgga tctgaaaagt tcagatacaa gcgatcaatc tcaccgtctt caaagtagtc
    18661 agtcaagtca gaaccatcta cccacaagag cttgatgtta gacactccag cttcaagcac
    18721 cttgtccaaa gcgtagctca aaacagactt ttgaatatca atcccgatat agttgatgtc
    18781 agggttttgc ttggccatac ctgaaacaaa ggcacccttt ccacttccaa cttccacatg
    18841 aatgggatta tcattgccaa acaagtcccg ccattttgcc ttggcttcca agggattgag
    18901 gaccacatac tggggatttg cctctagtaa ttctgttgcc cctttacgat ttctaactct
    18961 catcttctct ttccatactt gtctcggaaa tgacgcaaac catgaatctc ccgattgaca
    19021 ttttctaaat cttggttcat ataatacttg gaaatctgac tcaaataaga caattgacca
    19081 taccaataca atttacttaa taccgtttga ttgtacttgt aaccgtagta ggtcaaccat
    19141 tccttccact gatgttctga aatataatgg cagagcatat gggccacatc aaacatgcga
    19201 tcggtcaagc gaaccgaatc ccaatctact aaataaatca agccactatc tgtctcaatc
    19261 caattactat gtcgtacatc tccatggaca atggtcgcat ggtcctctct aaatcctgga
    19321 atagtctgac gtaaatcagc catcacttca ctgataaaat gatttttacg caaagcatct
    19381 ggagccgttt cttgccaaga ctgtagtaaa tctacaggtg tttccatggc atagcccaaa
    19441 cgactcaatt gtgtcatcaa cggacgtgag cgatgaagac gggttaaaat attgacgatt
    19501 tgcttacgat tcatatcata gggggtcaat atcttgcctg tcaaccattc ttgagcacac
    19561 atatcacgcc catctgccaa acgacgactc cataataatt gtggagcaat ttgttctcta
    19621 gctagaccag gtaggattgg agaggtgttc atttttacaa agatgcgctt cccatcagga
    19681 tagctaccca tataagcctt gccacttttc ccaggtatgg gagtcagtgt tagctcatta
    19741 tcacccaaat ccatttcttt cctccgtata aagtttcctt actattctac tagtttttgg
    19801 cctattcgtc aaccactcta acccgattct caaagaaaag cctctggatt ggcttgggta
    19861 tcattatagc ttgaaaaagg taagcaccgt cttctgctta ccttttcata atttttataa
    19921 ataatatagg agtggccaac tgttgtaaaa catgtggact agagtagaaa cccataagtt
    19981 ttggctcttt ttataagcaa ggcccagcaa caagccccca agtagataaa aaataaacga
    20041 agggacatta gaaggtccat gcatgaaaga aaagagagag gaagttagca caagtcctaa
    20101 ccaagaattg tcaaaaaccg caccttgaag aagtcctctg aaaatgagtt cctcctggat
    20161 ggggccaaaa actgaggtag tcaaaatcaa agacagggaa attcctctgc tgacttccgc
    20221 caagtgttgg acccctgagc cagaagaaac agcgaagaaa tgaatataaa ccagcgtctc
    20281 aagtacactt agaagaaaga ttgcaatgaa aagcaaaagt tgtttcttgc ttaacatccc
    20341 aaaagaaatc atttcaaact ttctagcata agcaacactc agcgaggtta caagaagact
    20401 tacaataatc aatgcagatt cattttgaaa aaaatcccca tggttaatcg tataaggaac
    20461 tgtaatgaca attattagta ctaaaaatcc aaaacacaag gcatgaaatt tatcaaaaaa
    20521 ctccataaaa ttatcctcct caacaaacag acttcctaca cgtcattctt tagttctagc
    20581 ctttccaaaa caaaccattt tatactcttc gaaaatcaaa ttcaaaccac gtcaacgtcg
    20641 ccttgccgta ctcaagtaca gcctgcggct agtttcctag tttgctcttt gattttcatt
    20701 gagtattagt aaccaaaatc cgaccacata gccagcccct atgaatatag ccattaaagc
    20761 tagcatggaa tttaggaaat taaaaaccac cgcagataca aaggttagca caaaaacatt
    20821 aaaagcaatg gtgtcagaag ccaagactag aatatagggt gtcaaccgat ctaaagtttt
    20881 ggaatctagg aaaaataagt gtttatacat gatgacctcc tctatggctg aaaagcaagc
    20941 cttttgtttt tttaccccaa gaccctatgt agaaaagtga gcaaaaacgg gaaggtcgct
    21001 acaatattat tgatcacatg caccgcatag gatggataaa tactcttggt atagcgggtc
    21061 aaaccggcaa agatgattcc aaatgttgca aagacgaaga tatctaacag actaggcaga
    21121 ctcaaaaaat gaggaagagc aaacaaaatg gaaggaagaa gcaaatcaag gccaaatcgc
    21181 gaatgcttaa agaaggcgtg ttgaagtaat cccctataaa tcaactcttc cattagtgga
    21241 gtcaggaaaa acagggttac atagatacct agctcagcaa agttggtccc actataacct
    21301 atcaatacag cccaaccttc agcagttgac tgaacatgtt tagctgtctg aacgttaaaa
    21361 gagatctgga gcactaccac taatactgtc aaaatcgaat accaaagcca tttttttctt
    21421 ggaatgtgaa agagataacc atgacctgtc ttaaccagaa tccaaatcat gactccgcta
    21481 aatagcaaac tcaagaaatt ttgaatccag acgaaattgc caatctggga agaaaattgc
    21541 caataatttt gaataataag cgtcatctga gaaagaccaa atacgaaaaa taagtaagag
    21601 aaaactgcac ttattttgaa tagaagttga tactttttca tagaaattct tcctcatttc
    21661 ttgtatttca gcctatattc cacataaatg aaaacctgct cctatataac cacggtcatg
    21721 ataaccgcgc gggcagtaac cacttactgg aaaaggacct gaatttttta atataggagg
    21781 gtaagaaccg aatggactta cctgattagc gtaccctcta taaatatcag atacatcccc
    21841 accctctata cgagcaagca tttcattatc cataactgca aattgtgaca tcatttttgt
    21901 atccatatag tatatcactt ttcagttacg gaacaagttt aatataaaaa ttatcaaaaa
    21961 aacataggca ataaagagaa aaattaattt atcatagatt agaaataata tgacaaaaca
    22021 attcaatgat gttaattcaa tagtcttttg ttttttatcg gagatactta tggatagata
    22081 aataagatag gtttgaaaag cgaagagaat aataaagaat atagccttca taaaatttag
    22141 ctttcatttt tatgatgtag cggtataggc taaatatcca caaaccactg ctcctccaat
    22201 tcctcctatt gcagcgcccc atggtcctag aagtctccca tatttcactc cacccgctgc
    22261 acaaccaaaa gcagcaccac caccttctaa gacattagtt tgccaattat tcttgcctcc
    22321 ttcaatacta gataacatag ttatatccat ttcatgaaat tgttccataa tttttgtatc
    22381 catgacaaat actctttttt atttttaatt tttgtcttgt tgtaactttg acaagtttag
    22441 tatatcatcg ttttttaaaa tttttcatcc agatcttgaa tagtcatcga aacgtcttga
    22501 attgcaaaaa ttacattaga cttcctgcaa aactagaatc ctagttcatg attgataatg
    22561 ccagcaatca aattcattcg taatccgaag cgtttacgat gatttcgata ggttgttgaa
    22621 aacattttaa acgtttttac tttggcaagg atgctctcaa ccttgcttct ctccttagat
    22681 aacgcatggt tataggcttt atctttaact gttagcggtt tgagtttgct ggatttacgt
    22741 ggagtttgtg cttgaggata tatcttcatg agcccttgat aattactgtc agccaaggtt
    22801 ttaccagttt gtccgatatt tctgcgactc attttgaaca acttcatatc gtggcaatag
    22861 ttcacagtga tatccaaaga aacaattctc ccttgacttg tgacaatcgc ttgagccttc
    22921 atagcgtgaa atttcttttt accagaataa ttggctagtt gattttttta ggacgattta
    22981 tttttacctc tgttgcatcc acaatcaccg tatcctcagc actaagatga gtttttgaaa
    23041 tcgtaacacc actttgaaca agagttactt caacccattg gctccgacgg attaagttgc
    23101 tttcgtgaat accaagatca gccgcaattt cttcataagt gcggttctca cacatattga
    23161 agagtggcca taagaaggtc ttctaggctt aatttaggtt ttcgtccacc ttttgcgtgt
    23221 ttaagttgat aagctgtttt taataca
//
LOCUS       DAVHSY010000029        23206 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.030, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000029 DAVHSY010000000
VERSION     DAVHSY010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23206
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.030"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            117..251
                     /locus_tag="VVR43_001429"
     CDS             117..251
                     /locus_tag="VVR43_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU6149780.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLK
                     "
     gene            309..674
                     /locus_tag="VVR43_001430"
     CDS             309..674
                     /locus_tag="VVR43_001430"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU6149781.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            671..1861
                     /locus_tag="VVR43_001431"
     CDS             671..1861
                     /locus_tag="VVR43_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU6149782.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            2039..2465
                     /locus_tag="VVR43_001432"
                     /pseudo
     CDS             2039..2465
                     /locus_tag="VVR43_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2536..2694
                     /locus_tag="VVR43_001433"
     CDS             2536..2694
                     /locus_tag="VVR43_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEU6149783.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(3062..4789)
                     /gene="ezrA"
                     /locus_tag="VVR43_001434"
     CDS             complement(3062..4789)
                     /gene="ezrA"
                     /locus_tag="VVR43_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU6149784.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(4871..6817)
                     /gene="gyrB"
                     /locus_tag="VVR43_001435"
     CDS             complement(4871..6817)
                     /gene="gyrB"
                     /locus_tag="VVR43_001435"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU6149785.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTSLTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(6832..7395)
                     /locus_tag="VVR43_001436"
     CDS             complement(6832..7395)
                     /locus_tag="VVR43_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU6149786.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(7480..8034)
                     /locus_tag="VVR43_001437"
     CDS             complement(7480..8034)
                     /locus_tag="VVR43_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU6149787.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(8045..9268)
                     /locus_tag="VVR43_001438"
     CDS             complement(8045..9268)
                     /locus_tag="VVR43_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU6149788.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(9305..11755)
                     /locus_tag="VVR43_001439"
     CDS             complement(9305..11755)
                     /locus_tag="VVR43_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU6149789.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQKNDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSCRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(11955..12884)
                     /locus_tag="VVR43_001440"
     CDS             complement(11955..12884)
                     /locus_tag="VVR43_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU6149790.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            13024..13311
                     /locus_tag="VVR43_001441"
     CDS             13024..13311
                     /locus_tag="VVR43_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU6149791.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFSAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(13345..14679)
                     /gene="ciaH"
                     /locus_tag="VVR43_001442"
     CDS             complement(13345..14679)
                     /gene="ciaH"
                     /locus_tag="VVR43_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU6149792.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(14669..15343)
                     /gene="ciaR"
                     /locus_tag="VVR43_001443"
     CDS             complement(14669..15343)
                     /gene="ciaR"
                     /locus_tag="VVR43_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU6149793.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(15452..17998)
                     /locus_tag="VVR43_001444"
     CDS             complement(15452..17998)
                     /locus_tag="VVR43_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU6149794.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVCSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(18121..18561)
                     /locus_tag="VVR43_001445"
     CDS             complement(18121..18561)
                     /locus_tag="VVR43_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU6149795.1"
                     /translation="MTPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(18536..19405)
                     /locus_tag="VVR43_001446"
     CDS             complement(18536..19405)
                     /locus_tag="VVR43_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU6149796.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLDTICSFYLDKEVWYRFSELTNTEANCLAGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(19383..19883)
                     /locus_tag="VVR43_001447"
     CDS             complement(19383..19883)
                     /locus_tag="VVR43_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6149797.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(19894..20592)
                     /locus_tag="VVR43_001448"
     CDS             complement(19894..20592)
                     /locus_tag="VVR43_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU6149798.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(20585..20851)
                     /locus_tag="VVR43_001449"
     CDS             complement(20585..20851)
                     /locus_tag="VVR43_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU6149799.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(20917..21843)
                     /locus_tag="VVR43_001450"
     CDS             complement(20917..21843)
                     /locus_tag="VVR43_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU6149800.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(21918..22733)
                     /locus_tag="VVR43_001451"
     CDS             complement(21918..22733)
                     /locus_tag="VVR43_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149801.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSIFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(22737..23057)
                     /locus_tag="VVR43_001452"
     CDS             complement(22737..23057)
                     /locus_tag="VVR43_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU6149802.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         7205 a         4875 c         4130 g         6996 t
ORIGIN      
        1 taattttatt tataacaaga ggatagaaat gaccgaatta gaaagaaaaa atcgaaaaat
       61 tagctaagaa atattctgat aacttaaaca tcaaagttca agagagagtt cgtgaaatgg
      121 caaatgataa taagagccat tatttgatat acagagtttt aggtatttca tttgaagaag
      181 gagaaaatat cgatttgtat caaaataaag gtcgtttttt atacaaatat gctggttcat
      241 ttttaaaata agctgcagta ctatgcttta acgaaaaatt tggtacagaa aatacttaaa
      301 aagttaacat tcctaattct gaaagtacaa aacctaagac ttttgaaatt gattgtttag
      361 tcggagaaaa acacgcatac gaaataaaat ggtgggatgc aactacagat ggagaccata
      421 taactaaaga acacactaga ataaaagtta ttcataacaa aggatatata ccaattcggt
      481 taatgttcta ctatccaaat agaactcaag ctataaaaat tcagcaaact ttagaaacat
      541 tgtataacgg tattggaggg aaatattatt atggagattc tgcctgggaa catttaagag
      601 cagtgaccgg tattgattta cttagtattc taacagatat tgcaaataaa aaaacagggg
      661 taaaatcaaa atgacagtat taaaaggaga taacttagaa atattaaaaa ctattgaatc
      721 ctcaagtatt gatttaatct atatggaccc tcctttcttt acacagaaaa cccaaaaatt
      781 atctaataac aaaaatatta tgtattcatt cgaagatacg tggacttcga ttgaggatta
      841 caaagaattt ttgtctgtaa gattagaaga atgcaaaaga gtgctaaaaa atagtggcag
      901 tattttcgtt cattgtgata aaattgcaaa tcatcatatt agattaattt tagataatat
      961 ctttggagca gatatgtttc aaagcgaaat tatatggaac tataaacggt ggtctaattc
     1021 aaaaaaggga ttattgaaca atcatcaaaa catttacttt tattcaaagt caaaagattt
     1081 taaatttaat acaattttta cagagtattc ttctactaca aatatcgacc aaatactagt
     1141 ggaacgaaaa cgagatggaa actctaaaac tatatataaa gttgataata atggtaacta
     1201 tattctagca aaagagaaaa atggagttcc cctttcagat gtttggaata taccatttct
     1261 taatccaaaa gctaaagaaa gagtaggtta tcctacacaa aaacctattc tgttattaga
     1321 acaaattata aagattgcta ctgataaaaa tgatatagtt ttagacccgt tctgtggaag
     1381 tggaactact ttagtagcct ccaagatttt gaatagaaat tatatgggga ttgatttatc
     1441 tgaggaagct atcaatataa ctcagcaacg tctggaaaat gttataaaaa caagttcaaa
     1501 tttattgaat aaaggaatcg aagcatatag aaccaaaact gaggaagaag aaaacattct
     1561 taaattatta caggcaaaaa ttgttcaaag aaataaagga attgatggtt ttttacctaa
     1621 acattttcaa aaaaaaccga tacctataaa aattcaaaaa aataatgaat gtctgaatga
     1681 gagtatctct ttattacaga atgctataaa ctccaaaaaa cttgattttg gagtagttat
     1741 aaaaactcat tcagataatt tattatttga ttttgatacg attcctgaaa atataatagt
     1801 agttgaccat tttgaactta caatcgaaaa atggttaagt aaaagtcaac agttactata
     1861 gtttgcaaat tatttacaga aagaacaaaa attcctagga gattattctg gctatgtgca
     1921 ttgtgatatg ttgcggcagt aacttaggac tttagtcctc tagttctgcc tatgcgatag
     1981 cagtccaagg tttaggagca aggcgacgct aagcttggta aactacgaac cgctagaagc
     2041 ttatcgtcaa ctggaagaag ctgcacttgt tggatgttgg gcgcatgtga gaaggaagtt
     2101 ttttgaagcg ccccccaagc aagcggataa atcatcgtta ggagctaaag gtttagctta
     2161 ttgtgatcag ttatttgcct tggaaagaga ctgggaggac attgtcagct gatgaacgac
     2221 tacagaaacg tcaagaagag ctccaacccc taatggaaga cttctttgct tggtgccgtc
     2281 gtcagtcagt tttagcaggt tcaaaactag gaagggcaat tgaatacagc ctcaagtata
     2341 aagaaacctt taagactatt ttgaaagacg gacatctggt cctttccaat aatctagctg
     2401 aatgcgccat taaatcattg gttatgggac ggagtaaaag agtccagtgg actcttttag
     2461 cctaagctca gtttaaaaaa gcgagggtgg ttgttttctc aaagttttga aggagctaaa
     2521 gcaagagcta ttattatgag cttattggaa acagctaaac gtcatcaact aaatagtgag
     2581 aaatatctat cctatcttct agaatgtctt ccaaacgagg aaactctcgt aaacaaagag
     2641 gttttagagg cctatttacc gtggactaaa gttgtacaag aaaagtgcaa ataagaaatc
     2701 tccagattag gaactatccg tgagttctct agtctggaga tttttcaata gacttcgtta
     2761 ttggacagtt accaagttac tcaaagtaca gatttgaagc tgcagataag actgacgaaa
     2821 tcactttaat actaaatgaa aatcaaaaag caaactaaga gcctcaggct gtacttgagt
     2881 acggtaaggc gacgctgacg tgatttgaag agattttcga agagtataaa acactgtttt
     2941 gaggtggtgg ataaatcggc tgggcaaaaa ctcaatctca ggagaaaatg aagtaaatct
     3001 ccccacaact atagaaaaag atttgattct gctcctcaca caataaaatc tttttctttt
     3061 attaaaaacg aatcgtttca cgtgttttct catatgaggt aacaaagcga ttggttacac
     3121 caggctctgc cacttccaat gcttgagaaa tcttgtcaaa tgaagcgtga taatcaaatt
     3181 ctttttcaaa aatatctaaa gcttcgttaa atgcttcttg aatgcgttca tcaaatgagc
     3241 gatagcggtt agaatattgc aagagttgct ctgtcaaagt tgcatattgt acaatattat
     3301 aagtttccgt ttctaaagct tccatatcat tcgttgcaat ttcaagaact cgggtaacag
     3361 attcaatgtt aatcattttt tgttctaact caaccattaa atcctcggta ttattgcttg
     3421 ccgtaaagaa taacttcaag aaagtttgtg gaatacctgg cagattgcgt ttttccatgt
     3481 atcgcttgat agtatggaga cgattgacat aaacattggc cttttgacgt gcattaatat
     3541 catctttctc aatttgtgtc aggcgctcac taactgaaat ttgctcatct tcaatatctt
     3601 ttagttgagt ttgtaaatcc tcaagatttt cttcaagaac tgaataagct tgggttggtt
     3661 cttcttgatt tgaagttacc tcaacaatag ctgcctcaaa actctctaat tctgtctgaa
     3721 tacgacgaac atggcttgca gctgtctcag gaagtaaata ggtcttgttc aaacgtgcaa
     3781 tatcttctcc caataaagta ttattctctt tcatatgttg aaggtaagtt ggaagagttg
     3841 caagtagatt ttccactact ttctgagcag caatttctcg agtaaaaata tcatacaagg
     3901 cattgatttc ctcttgtgcc tgtccattct catattcggc attatccaat tccaactgac
     3961 gaatattctc ttggtttttc ttgaatgctt cataaagcaa gtggaaacgc gcttcaatat
     4021 ccgtttcaac aaaatgataa ttagcatcaa ttagtttacg ataaccggct tccaaatcct
     4081 gtaattgatc tggcaattct gtagaaagcg tcgtaaccaa ggctggaaca cgatccacaa
     4141 tatgacttaa ggccaaaatg tgattttctg tattatccaa aatcactgcg gcttccacag
     4201 ggtcacccga tgaattcaag gttacaaatt gtgaaaattc agattggata ttttctaatt
     4261 gtttttcaat ttcatccaag gcttgaccat actgttctga attttcagca actctatgct
     4321 gaagttcctc aaataaatcc aaagcatgaa gaacacgacc actattttta gattcttgct
     4381 tctctaagtc tgccaaagca ttgcgaattg ccgcaatatc ttcttcaatc aaagtaattt
     4441 gactctcaat ttggtcaatt tgatgactgg ccttgagaaa acgaaatgaa tggttatagc
     4501 cttctgcttc aaagagatta ttttcaatat cggcaaaaga gttgagagat aaatcgaccc
     4561 atttttgatt ccattcacgg aaagccactt gactttgtcc aatcaagtgc atatttttta
     4621 cagcttctac ttcatcattt actggaagat tgtatagttc ttcttttctt tcttctagcg
     4681 cctctaatct cccctcgttt cgcttacgta gaaagattgc cactacataa gccagaacta
     4741 aaatgactgc aattgcaacc attaaataaa ttagttgtcc attagacata tcaaactcct
     4801 tttttacttg aaacaatcgt aacgattata tcatattttt tagaccaagg gaactacttc
     4861 tccctatttt ttagacatca agtgtactat agacagcatt ttcttcgata aactcacgac
     4921 gaggctctac tcgatccccc atcaacatat caaagatttt atctgcttct gcagcatcat
     4981 ctacagaaac tctagccatc aagcgatgtt cgggatccat ggttgtttcc cacagctgat
     5041 gatcgtccat ttcacctagc cccttataac gctgaatagt cggtttggta cgaccttcac
     5101 tataacgggc taaagcttct tggagtttga tttcttgatc tgcacccggc tggatatatt
     5161 ctttaatctc gcttccaacc ttgacaccat agattggtgg ttgggcaata taaacataac
     5221 cagcttctag gattggtttc atataacgat aaatcaaggt taaaagaagg gtacgaatat
     5281 gggctccatc gacatcggca tcggtcatca aaacgagttt ttggtaacgg gctttcgaaa
     5341 catcaaattc tgcgccaaat cctgttccca tggctgtgaa aagactacga atttcttcgt
     5401 tagctagaat cttatccata cttgcttttt caacgttcaa aatcttaccg cgaattggaa
     5461 ggatagcctg aaactcacgg ttacgaccag atttggctga tccaccagct gagtctcctt
     5521 cgacgatgaa gagttctgtt tcagcagggt tattagaaga acagtctgct agtttccctg
     5581 gaaggttgga aatttccaaa ccagattttt tacgtgtgac ttcacgcgca cgcttggcag
     5641 ccacacgagc cttggcagct aaaatccctt tttccacgat acgtttggca atctgtggat
     5701 tttccatgag gaaatcggag aaggcttcac tgaagaggcg attggtaatc ttgaccactt
     5761 cgctatttcc caatttggtc ttggtttgtc cttcaaactg tggatttggg tgtttaactg
     5821 agataactgc agttaagcct tcgcgaacat cttcccctgt taaattatct tcattgtctt
     5881 tcagtaactt attcttacga gcataatcat tgataacacg agtcagtgac gtacggaaac
     5941 cttgttcatg cgttccacct tcatgggtat gaatattatt ggcgaaactc atgacatttt
     6001 catggtaacc tgttgtgtac tgcatggcta cctcaactgt gatatcatcc atctcaccgt
     6061 ctgtatagat tggtgtatca aagattacat ccttgttctc gttgatatat tcaacgtaac
     6121 tagcaatccc accttcataa tgataatgct tggtttgttc caaaccttgg cgcttatcag
     6181 tgatagaaat ttgaagaccg cgatttagaa aggccaactc ttgaatccgt ttatttaatt
     6241 tatcaaaatc aaaggttgtt gtttcagtaa agatttttgg gtccggtatg aagtgaaccg
     6301 ttgttccagt tctatctgta tccccaacca cctcaaggtc tgcaacaaca tgaccacgac
     6361 ggtattcttg gtaatgaatc ttaccgtttt tatggacatg aacgtctaat tgagtggaaa
     6421 gggcattaac tactgacgac cccaccccgt gaagaccacc tgaaaccttg tatccaccac
     6481 cgccgaactt tcctccagcg tgaaggactg taaagacggt ctcaacagca ggacggcctg
     6541 ttttttcctg aatatcgact gggataccac gcccatcatc cacaacagta atcgaatcat
     6601 ctggctcaat aaaaacttga atatggctgg caaatcctgc caaggcctcg tcaattgagt
     6661 tatcaacaat ttcccagact agatggtgaa gaccttcttt tgaggttgat ccaatgtaca
     6721 tccctggacg catacgaaca gcctctaagc cctctaaaac ttgaatttga ctggcatcat
     6781 aatcctgtgc ctgcagattt ttgatttctt ctgtcatctt attccttttt cttatatgtc
     6841 taatacttgt cttaaattca cgatactggt aaacaagtgg gtatcaagtc ctgcagcttg
     6901 acctgcttcg atatcaatcg gccgatcacc aatgacaaga ccagagctaa tctgatactt
     6961 ttctcttaaa taaagcatgg attcgggatt tggctttctc ttaaagcctg agctagaagt
     7021 caccacttct gtaaaataag ctgctataga ggttttttct aaaatttcca aaacctgatc
     7081 atttcgatga gagaccaaaa aatgacggcc accttgattt gaaatgtctt ccaataggtc
     7141 agaaactcct tcaaataaaa tcgggtgttc aagctctctg gcttcatttt ccttgtactt
     7201 ttctaaaaaa ttctctaaat tgggagcgaa tgtctcaatc gcaaaaggag tagaaacctt
     7261 taaagcttga tagacactgt catggtcttg tgtgatacca tacagtgcca atgtttcaac
     7321 aaatgcagct gttgaagttt cataattatc cagtaaagtt ccacctaaat cccagatgta
     7381 atcgtgatat ttcataccct tcattatagc atttttttat gaaaaaagcg atgatttccc
     7441 tgagttttcc acataaaaaa cgagagaata actcccgttt tactgatttt taccaaagac
     7501 atcttgatag agcattcctg ttcgtaaact ctctgcgtcc cctcctagtt gctccaccaa
     7561 ctcgtaggca aaggcaaggg ctgttgaagg accccgactg gttgtcaact gaccatctac
     7621 cactactgtt tccttgacgt agtgaccatc aaggatttgc tcttgaacgc cgtcataaca
     7681 agtgtatcgc ttatttttca atatctctgc ttgattgagg gcaattggtg ccgcacaaat
     7741 ggctgctagt ttcttccctt cttgctcgaa gctttgcaat tcttgaatca aggtctgatt
     7801 atcacgtaaa tgtgcagaac caggcatacc tccaggaaga acaatcatat catagtctga
     7861 taaatctcca tcaaagacat gatctgctct tacttggatt gcatgcgaac ccgttacttg
     7921 ctcttcaaaa ccaaccatat cacatgtgat attggctcga cgcaagacat ctacaactgt
     7981 caaggcttca atttcttcaa agccctgagc taacataact gctactttta ccatgatttt
     8041 ctccttattt aatttgtttt aatacaacct ttttccgttt gaatgggact tttccgctct
     8101 tttcttcagc tagattagtc tggtaactca tcgataaaag caaaccaaca ccaatcagat
     8161 tactgataat agctgatccc ccttgcgaaa tgaaaggcaa gggaatcccc gtcaaaggaa
     8221 gtagtccagt cacagcaccg atattctcaa agatgtggaa gagcaacatc ataatcaaac
     8281 ctgtggaaat ataagtgtag aactggttat ttgatttaag agtaatcttc aacatacggt
     8341 aaatcaacat gagatagagg gcaataacca ggacagagcc aataaagcca aaatcttctg
     8401 caataaccgt aaaaatcata tctgactctc gaactgggat aagcagattc gaagcattaa
     8461 atccctgacc aaataagcca ccactcccaa tggcaatctg cccttgagcc tgctggtaag
     8521 tcgttgtttg ggcaaactca aagggattga gccaagccaa aatccgattg atttggtagg
     8581 tcggcattcc aatctggtga agaaaagctc gtccgtcctt gctaataaag atagctaaga
     8641 aaccagcaac tcctgttaca gcagtcacaa atactgggat aataattttc caagaaaccc
     8701 ctgataataa aacgattcct gagaaaatgg ctacaaaaac caaagccgtc cccaagtcac
     8761 tttgaagtgc taaaagaact aggactggaa tggtaaagag aatcatccag aaaattaaca
     8821 aaaagtccag cggaaccgtg cgtctccatt ccttatgttt ctttgtaaat tggacaatga
     8881 cacgagccaa catgaggata taggatatct tcataaattc tgacggttga aatagggtaa
     8941 ttccatttat tgatacccag tttttggcac ccgttgatgc aactaagctt ggattataaa
     9001 atacaatcgg caagatcata agtcccaagc ctaaaatata tagaaagggg gtcaccttcc
     9061 aaagaaattc tgtattaaag agcatgacca caaaaccaat cacaagcccc aaggcaatcc
     9121 aggcgacctg ctgccctaaa atgggcagaa tattattggg ataatcatga ctaacggcta
     9181 tatagatagc caccacaccg atgaccagta gaaaaaatac tggcaagagc aaactataat
     9241 cgactctaga gtcgagagaa cgtttcatat atactaacct tatactttca tacaatacta
     9301 tttatcaaag ttcattaaaa aatctatcaa tagcctcgtc aacttcggat cgagagatgg
     9361 ttttaacagt tgcttcttct gctagagatg ctactatttg tttgccgtat cgttttccga
     9421 tgattctcct atccaaaata agagttaagg aacgttggta ttcacgtctc atacttcttc
     9481 ccaaagcctg ttttaaacga ataatggcca ttggcaattg ataatcataa aaggcatttt
     9541 tcccttcttg attcagttct tgattaatct ttttcgtcaa gggttcttga ggattttgga
     9601 aaggaagcct cggtacaact tgaatcacaa aaggatggct tgaaaaatca actccctccc
     9661 agaaacttgc tgcaccaagc aagatttgtt gttcaccttt ttcaaagcgt ttctttagct
     9721 gatgaacatc cccattttta tactgggcca agtggctaac tgtaagtaaa tccgatactg
     9781 ctagaagcat gtctttagcg gtaaagagaa ccaaaatcgg ttgctggaaa gcttgaattt
     9841 ccactagtaa agcagctacc tctctggcat agacttctaa ggaggtttct gttaccagag
     9901 ggaaatcttt gaccataacc acttcttgtt cctgttttcc ccgagattca atcttgacaa
     9961 atttggcttc aggatagcct aaaaggtctg ccaaagaaac cctctgacta atctcaagag
    10021 tagccgatac tcccaagact tggcaactct caggaagtaa agaggacaga agagtacggc
    10081 atgattttgt agaagaaatc tgaattttct tttgactcgt ttcagttact tcaagccagt
    10141 aatcaccttc agctgtaaaa tagcgaacca gctcatcaaa gccttctact tctaattctg
    10201 aaaaatactg atggagattg tccagagaat ctaagatatt tttcctagat ttaccagact
    10261 gaaattgttc tatcaagtag agacactcaa agcgaatact ttctagtatc cgttgttgaa
    10321 ccctgttttc ttctcctact aaagccttat caattaaatc gataatagat tgtatatcgt
    10381 aggtctcttg aagcagattt tctagagcta acaaaatctt ttggacttca tcaataatca
    10441 gtaaacggtc actgacaaat tcaggattat cttcaagtct ggtcacgaga taggcatgat
    10501 tagtcactaa aagcttgcaa gtctctgccc tttcttgact acgtttccaa aaatcttccg
    10561 tcacaaataa gctctgggat gataaattcc catcatgacg aaggtctgct agaaaatgtt
    10621 ggtaacggta gagttgcccg atttcatcca aatctcctgt ctctgtctca gtaagccaga
    10681 ccaagacttg cattttaaag cgtctaaata agcgattttc atcatttttc tgcaaggaat
    10741 gataaaaggc atccaacttc agataatttt gtggtccctt taagctatga atatctgtat
    10801 ggaacacttc cttgaggcgt ttaccttctt cttccatgat ttgattttga agaatctttg
    10861 tcggaacact aagaacaatt tgtcgctctt tggattgaga taaagcgggt aagagatagc
    10921 cataggtttt cccaatccct gtcggcgctt gaatcagaga gacaggttca tctttcaata
    10981 gcaagccaac ctctttagca aaactttctt gttcctccct cacttcaagg ttcaacagag
    11041 aaatattttt agaaaagtct tgagatagtt ttcgtggctc cagagaagct gccgttttct
    11101 taaaatacag accttgaact tggaccaagt ctggagaact caggatagat tggttgcgat
    11161 aagtttcctc aataaccagg taggactcat ataggagagc gtcagccatt tccagcaagc
    11221 gttccaagag acctttagga agctgggtca tcttttcccg taaaaaaaga agtaattctg
    11281 ctgtagcttg ggcatctgaa agggctgtgt gtgcgtgttt aagaggaatt cctaattctc
    11341 gacacaaaat cggcaagcta tatttttcca gttcagggaa aaagacctgg gccaattcga
    11401 ccgtatcaac acgagggttt cttagctcat agccttcaaa aaataaattt tccgccaaga
    11461 gattagcatc aaactgaaca ttatgggcta caaaaatccc atcctccacc aagtcaaata
    11521 tttttctggc aacttgcgaa aaatcaggtg cttgcgccag acgttggtct gtcaatcctg
    11581 tcagttcttt gatatgagca tccaagggtt catgtggatt gacatccgtc gtatagtgat
    11641 cgacgatttc tccgtcctca atcacgacaa ttcccacttg gataatttta gccttactac
    11701 ctgtgctagt tgcctctaaa tccaccacaa catagcgatt accaatcgtt ttcattataa
    11761 aaaattatac caaaaaaagg gccatttggc acctgcaaac ataggataat tttcaaactc
    11821 aagaacacta cttttcttaa aaatcccatc gaatagagca ttctagcctg ctgatttttg
    11881 taaaatagtg aagaaatacg aaaaattgag agaagaaatg tttgcatctt ccttctctca
    11941 acgaatcatg tattttatct aaccatgtca ggatcgtagt cataaaatcc tgtatcaagg
    12001 aaacggtttt tagggtgaag tttacgaact tcttcatcca gcaagaaggc ttgatcatgg
    12061 ctaaagttgc cctcttgaat caagttacgc gcttggataa agagttttgc aatctcaaca
    12121 aagttctgac caggagtgta gagcccttct agtttccagc gagtaaagcc atgctccacc
    12181 aattctgtta atttgatcat caaatcaagg tcattgttgg caaagatatg ggtcccatga
    12241 ttatcttcaa aaatggaata gtggctctct ggatcacttg gctcagccaa gaagaggtca
    12301 cgtttatgcg tcttttcatc atcgatatgt gtaaagttat agtagttttg caagagtgga
    12361 cgtttagaat gatggatgac gctagcaccg taaaccaaaa cttcagcagg aatttccaaa
    12421 atctctggca ttttgaaaag ttcagctgat ggaatttcac gcgccaaaac agcctcagat
    12481 gcgccagcct tttgtcccca gaagttaatc tgacgactgc tagttaccat ggttgaagca
    12541 tcgtagatgg tcttaaatga ataaccatcg cggttaacta cgtaaaagac gcctgcatcc
    12601 ccaatcgtaa tatagtctgt cttgatttct tccaagaagt ctaagaaagg cttgatacgg
    12661 tccatcatat cttggtgcat gagagcattg accgcaacga tcaattcctt accagcatca
    12721 tgaaccaact tagcgatttc acgtaattgg tcataactaa aggtcgttgg cagacgaagg
    12781 ccaaaatctt tctcaccgac atagatacgg tctacgccag cttcgagtag ttgttcaact
    12841 tgttcaatac tttcagcagt tgctgtaatg acaatctttt ccataagaaa aattatacca
    12901 catttctcca aaatcatcca tgctttgaaa atgaaaaggg actttattct ttttgtaacc
    12961 tttctgtaat aattctctgc cgaaaaaatg ataaaatagg tatgtactgt taaggagaga
    13021 attatgcccg taagaaaatt acaatcctat gaggtagact atcaagaaga attaaaccag
    13081 cagcttcctc attaccaagc ttatacacct gaagcgcaat ctgatgccaa tctcaaggaa
    13141 atcctatttt ttattaatat cgctgttttt tgtatctgta ttgctatctt tagttttatc
    13201 tttttagcat taaaattatc aactgctctt gccttttccg cagcaatcgg attcagctta
    13261 cttgttttaa aagttcaacg gtctattatc aaacgaaaac gtagaagata aatccaaaat
    13321 atcgccccag ttggagcgat atttttattt tttcttttta gatggtgtct gaatggcaat
    13381 cttcacttca aagattgttc ccttgggttt attatctttg acagtaacag ttccttttag
    13441 agcatctaca atttgcttgg ctagggataa tcctaaacca aaaccacctt tttgccgggt
    13501 tctagctttg tctactcgat aaaaacggtc aaaaattttc tttttatctt ctgtcgaaat
    13561 accgattcca ttatcagaaa caagtaaata aagattgcga tcggtcgccg agataagaaa
    13621 atcaatttca ccatcctcct cagtatactt gacggcatta tcgaaaagaa tggtcatcag
    13681 ttgtttcaga agaagctgat ctgtgacaat tgttcgatgg atacgatttt caaaacggaa
    13741 gacacgatta ttttccgaag caatcatctc gtagtttgtg aaagttgtat taaaaaagct
    13801 agttggaact tctgcaagct ccggcttaat cccatcatct ctccgagcta agttcagcaa
    13861 gcttgtcgtt aaaaaacgca tatttcggac ttcttccaaa ctcgatgcaa tgctttcgct
    13921 cacatccata atggtagctt ctggcttacg aaaaagggtc tctaagcgat tttgcaaaac
    13981 tgcgagtgga gttcgtaact catgactggc attttccaca aaagactgtt gcttctgcat
    14041 actctcaagc aggggcctaa cactgaccct agctagatag agactggcaa gtaaagacaa
    14101 aatccagaaa ctagccatca cgaccacaat caattgctca tgcttttgac tagcctgctc
    14161 caactgactg gtattaatca agacagcagc atacttgata ttggttgaaa ccgaactaat
    14221 attggtctcc atcaaaatca cacgatagat ttcttcctgc ccatagctat taaaaacctg
    14281 aatctggtag atatgtccta gttctttctt ttctaactta atcttatcca agcccaaaaa
    14341 tcgatttcca gaaagaagtt gagtaaagtc tttatcaaag agaatgactt ccgtattgga
    14401 actgacatta ggttttattt ctactttact agcgtccgcc ctagcatttt ctaaatcttt
    14461 aatctcttct gttgccctat ttatagccag ctgaataact gcttgaggat tttcactcag
    14521 tccatgaagc ttatcgtcca ccgaagtata aagactcgaa tgcatgactt gtaaaataat
    14581 cagagtcatt gtagaaaaaa tcagggtgaa gacaccgaag ttgcggataa aataactaaa
    14641 gtcatccgca taccatgttt ttttaagttt actgaacatc ttttaaaaga tacccaacac
    14701 tacgcaaggt ttgcaaattc tctgcaaaag tggttccctt taatttctta cggacttttg
    14761 aaacatagac ttcgacaacc gaaatcgttg tatcactatc aaatccccat agacggtcaa
    14821 aaatctgcgt cttaggcaaa atcacatttt gattttgaag gaaataaact agtaaatcga
    14881 actctttccc cagcaattcg acaggagtat cttcaacttt aacggtattg gttgataaat
    14941 taaccacgat attcccataa gtcaaggtgt tttcattaaa cttccctgaa cgtttgagaa
    15001 gggcctgaat ccgcatttta agttcttcta ggtagaaagg tttggtcaga taatcatccg
    15061 ctcccagttc aaatccatgt cccttgtcat ccaaactttc cttggcagtc ataatcagaa
    15121 ctggtgtcgt aattcccttt tcacgcaatt cttttaagac ttggaaacca tttttttctg
    15181 gcaacatcaa atccagcaaa atcaagtcat agacaccact ctcagcttcg tagagacctt
    15241 cttctccatc aaatacctgc ataacatccg caaaatcgtc taaaaagtca aatactgaat
    15301 ttgacagacc taggtcatcc tcaaccaata agatttttat catgagaaac tcctccttat
    15361 taaaactatt ataccaaatt tgccttaaaa aaaactcaac tctctgcatt ttacatgaga
    15421 tagctgagtt ttctttttat tttaggctta tttatgcatt tccgtattga agaacaactg
    15481 cttcgactgc agctttttca cggctaatca agtcaacacg cgctgcaatt tccttgattc
    15541 ccataccgat gttacggcta agagcaaggt cagaaagttg cggttcaaag aactccttgt
    15601 attccgccaa gcgttgctga gtcttaaata catgagcagg aaggataaca aagctatcaa
    15661 agctcatatc tcctccaagg gctgccttaa tccaagccca gttttcacgc gcccaagacc
    15721 aagctgtttt ctgagttgct tgatgagcta ggaattggta ataccaagca gacaagtcct
    15781 gtggtttgac cacaaatttg tccttccaag aagtaatcaa gttttggata ttatccgcat
    15841 ctgtactgta tgcaagagct gctgccaact ggcgtttaaa gacagcatct gttgcgtgag
    15901 tataagtatc aagataaagt gctaacaagt ctttagtctc atgatgtttc atctcattaa
    15961 tcagaacttg tgaacgaata gctgctggga gtcctgcaag attctccttg tgtgttgcga
    16021 agatttggct agcgacttga ctagcttctg catcatttga gcgaatcatc atcgaaacag
    16081 ccagctgacg aaccaattca tcctcatctg attctccgtc tttagcttca aaaccaagac
    16141 ggtcatagtt atgacgagcc aatttagcaa ccagtccttt gaaggctgtt tcagcatccg
    16201 ttccttcatc aataaagcgc tcaagggctg aaatcacttg agaaacagct gaaaccacca
    16261 gataagactc ttccttagca agtttatcaa gaactggaag caagtctgca taagaaatgt
    16321 gccctgcctc agccaacaaa cgacgttctt gaacaatttg cagtttgctt gtgttatcaa
    16381 gtgtctctag ctcagcaaga acagcttcta acaagtctcc ttgatagtcg gtaatatagt
    16441 gggcagtatt ttcagtgttg agacgaagag ctccttcatt ttcagcaaga agagctgcgt
    16501 agccagggat ttcgatactt tcagtttcga gtgtatcagg caagcctttc cagttgctat
    16561 tgaggggcac cacccagaga cggttcttgt cttcgttctc accgatgaag aattgttttt
    16621 gtgaaatctt caagacatca ttttcaactt tgacagtaag aactgggtaa ccaggctgtt
    16681 ccaaccaaga atccatgaag gctgcgacat cacgtcctga cgcttgacca agggcatccc
    16741 aaaggtcact accaatggta ttgctgtatt ggtgtttttc aaagtaggcg tgcaaacctt
    16801 tagcaaaatc agcatctcct agccaacggc gaagcatgtg catgagacgg cttcctttgg
    16861 catagacgat agcgccgtca aagagtgtat tgatttcatc tggatgttta acttcgacgt
    16921 ggacagactg aacgccatca gtagcgtcac gttcaagagc aagaggtact ccacctgttt
    16981 ggaaatcttc aaagatattc cagcttggtt cgatggtatc cacacagacg tattccatca
    17041 tattagcgaa actttcattg agccaaaggt catcccacca tttcatagtc acgaggttcc
    17101 caaaccattg gtgagccaat tcatgggcca caacaagggc aacttgttga cggctagcaa
    17161 atgtagagtt ctcatcgaca accaagtaaa cttcacggta ggtcacaaga ccccagtttt
    17221 ccatagcacc agctgagaag tcaggaagag cgatgtggag agattgagga attgggtact
    17281 taactccata gtaatcttcg taaaactcga tagagcaaac agcgatatcc agtgagaaat
    17341 caagatttga aagtggatgt gctttggttg agtagacacc taccagggta ccatttttag
    17401 ttttagcggt caccccttgc aaatcaccag caacaaaggc caacaagtaa gaagacatgc
    17461 gaggtgttgt ctcaaacttc cagatacctg tttccttacg gttttcaaca tcgatttctg
    17521 gcatgtttga caaggccaat tcaccttctg cttggtcaaa gcgaagagag aggtcaaaag
    17581 ttgctttggc ttcaggctca tccacacatg ggaaagcttc gcgcgcaaaa tggctctcga
    17641 actgagtaga caagacctcc ttcttgactc catcaactgt ataataagaa gggtaaatcc
    17701 ctgtcatgtt gtctgtaatt ttaccagaaa aggcaagaac caattcaact tgaccagcct
    17761 cagccaattc gatatgaagg gcttcattgt catggtcaac tgtaaatgga cgagcttgac
    17821 ctgcaacttc tacagaggtg atttccaagt ctttttggtg gagggagatg cggtcactct
    17881 gtgcttgacc agtgatggtc actttcccag aaaaagtctt ggtctcacga ctcaaatcta
    17941 aaaataaatc ataatgttca ggaacaaatt gcttaataaa atgttcaact gcttgcatag
    18001 ttttctccta ttctaagttt aagagctgct gctcttcttc aaacaaactt attatatcat
    18061 attttgcttg agaaaaaagg attggacagc gatttccaaa actttcttcc ttctaatagt
    18121 ctacagtggg tagaccttgc gaaattcttc taaaacaacc ttgctttcag gtgtaaaagt
    18181 cagccctact tcacccaaac agtctgtgaa aaagtcctca tgaacctggc gccaataggc
    18241 aagtgatttg tctccctcac cttccttaaa ggcatgttgc gcagaaactt gattgaagag
    18301 ttcaacagaa acctttgtaa tttcgacaat gcagacagac tgattttgac tatctaaaat
    18361 gacatcgaag gtccctactt ggggaagtgg ttcgtcttct agtacataga ggtcataggc
    18421 tgatgctgtt gctgtctttt ctcctttaaa caccaaatcc gctaaaaggt ctggttcaac
    18481 tccaaaagcc caagcatcga tttcatctcc gatcaaagga ttgatttgtt tgtatttatt
    18541 ccacatttct tgcggtgtca tgggtgctcc tttgtaattt tttactttct tcttttatgt
    18601 gtttaagatg atctggatgg tcaatctcta aatcaaaaat ctctggaata gaactgtagt
    18661 ggataatgca cttgataccc aactgattca ttttttgtat gaaagaagta ttcagatagc
    18721 ctgctacagc aaaattaatc ttgttctttc ttgctttatc ctgcatatct cttagcatat
    18781 ctaacattat tggactttcc atatcatgcc attgactgtt tctcatagtc gcaaaaacaa
    18841 aggaagtcaa atcattcatt ccaactacaa tctttgaaat gcccgtttcc agtatactag
    18901 ataagtcaaa atacgctgac ggtaattcaa tcatcgttcc gactttccca gtaaagccat
    18961 actgacgcaa tactgtaata gcttgtttta attggtcggc atcattgaca aaaggaaaaa
    19021 taagagacag attgggattg gtttgataaa cttctgtaac gacatgtgct tcagcctgaa
    19081 attcatccaa acacgccagt aaacgcctgg ttcctctata gccaaacaag ggatgccctt
    19141 cgtcaaaaaa ctctctagtc cccgctaaac aattggcttc tgtattcgtt aattcagaaa
    19201 aacgatacca aacttcctta tctaagtaaa aggagcaaat agtatcaaga taatctttta
    19261 caaattgctg acaacttgct aatatgatgt tttgattaag ctctctcaac aaatattccc
    19321 cacgaatcat gccgacgtgg tgaaatagtt gaggataaat tttttcaaga attttttcgc
    19381 cactaagggc aagttgattt ctcatcattc accttccaat tcatgtaaga agtcttgtcc
    19441 agttctggaa atcctaataa ttcagactta accttcaaga ctaatggcga tgcattttct
    19501 tctgtaatct cttgaatatc catccaaata tatccaagtg aatcattcgc accatcagac
    19561 acagcttccg aagtcgtaac ttgaggtgca ctctcattca tttcaacatc atacaaggcc
    19621 atgacatggt gaaccataaa atttgttaac tcttctctga cgaaaacatc gtagattcga
    19681 ggattagagt agcttctaac agtaaatccc gtctcttcca taacttctct agtcagcgtt
    19741 tccgtcagtc cttcaccaag ttgctgactg cctccaggta gatcataccg atgttgataa
    19801 gggcctctcg ttttttcaat gcagagtaac ttcccatttt ctaagcaaac agcgtagact
    19861 ccaaagtgtt ttttgatttc catccaactc ctcctacttc aaagaccagc caccatctat
    19921 tgtcaagatt tgtccttgca tggcgctcgc ttttccactt gctaaaaaaa gactaagctc
    19981 tgctatttcc tctggctcaa tccagcgctt gattggggtt tcactagcca cccagtcagc
    20041 caaaccacct ggttcaaaat ccgcagcggt catagctgtc ttgactgctc ctggagcgat
    20101 accaaagacc tgaatcccag cttcagcata gtctagagcc aactgcttgg tgaagccagc
    20161 caaggcatgc ttggatgaag tataggcgtg accacctcca cctgctaggc tagaagcaat
    20221 ggaacacata ttgatgatga ttcccttttt attttccagc atttgtgtca aataataccg
    20281 agtcaactct actggaataa tgtagttgat ttcaaaaatc tcttgaatgt cctgcgccgt
    20341 ttgttccaac agtggtttgt aatcatccaa aactccagca gtattacaca aaacatccac
    20401 ctgagggcac cagtcaaaaa taggttccaa gtccaaggtc aaatctctct gtaaaaagtg
    20461 aaaatcaccc tctaagagtg gcttttcacc ttggtcaact ccataaactt gatagccctt
    20521 ctctaaaaag aggcgagctt gagccaatcc gatccctgaa ctcactcctg taatgagtac
    20581 acgtttagtc atgcacttct acccaatccg ttgccaaaac atcacaaact gtcgggctcc
    20641 acatggaaaa accttctcct tcgccagaaa cgttgattag gaaataaggt gtcatttcaa
    20701 gtgcaagccc attttgctcg atggtatcaa agagttggac atagttttcc gcacctcccc
    20761 aaccagttcg tacatatttt ctcttagcct ttaacccagg caggatctct tcaaatgtca
    20821 tgtttttctc ctttaattct acattcttca tttaattata gcaaaaaacc gctttatacg
    20881 gctttttgaa tgtgagttat tcaaacctgc tactacttac ggcaaattat tccctgcagc
    20941 aagataaatt tcataccatt cttttcttgt taagctaaag tttgccgctc ggctaacttc
    21001 tctcaagtgc ttaggatttg ttgtacctac gactgcctgc atttttgctg gataacgcaa
    21061 tatccaagaa atggcaatag ttgaagaggt tactccatat ttaatagcta aacgatcaag
    21121 tacttgattt aaagcttgaa atttctcatt tccaacaaaa tttcctttaa aatacccgaa
    21181 ttgtaagaca gaccatgctt gaatgaccac atcgtgtaat tggcaatatt caaaaatgct
    21241 gccatctcgc atagctgctt gactatcttc catattaaca tgaaaagctg attcaaatcc
    21301 tggagtaaaa gccgcactca attgtagctg attaacagct aacggctgct tgacatcttt
    21361 tttaagcaac tccatcatca taggattttg attagaaact ccaaaatctc gaactttacc
    21421 ttgtttataa aggagatcaa aggcttctgc tacttggtca gattccatca aagcatctgg
    21481 tcgatgaagg agcaagctat ctagatgatc aatcttcaat ctttgcaaaa taccgtctac
    21541 tgattttata atatagtcct tagaaaaatc aaaataggta aattcttcaa tgcgaatgcc
    21601 acatttggac tgaatccaca tcttttctct taaatctgga cgatttttta ggacaagacc
    21661 taacagttct tcacaacgac cacgaccata aatatcagcc aagtcgaagg cattgattcc
    21721 aacagaaagt gctgtttcta caagctcttc aacttctttt acagatttat cttttattct
    21781 catcattccg agaacaattt ctgataattc tttgtcatct tgaccaagag ttatgtatct
    21841 catcaaattt ttctccttta atttctaaca ttcttccctt cattataaca aaaaaccgct
    21901 ttgcaacgac tttttgacta tacttcactc cattttatct tcttaaaccc acggaacaag
    21961 acaaagattc caataaagag gacagctaaa ggaataactt ttgtaaggaa aacatttgaa
    22021 attcccatcc actcataata acggagcaga gaacccacca caagatgggc aataatcata
    22081 ctgacaaatg gacgaaagac cgcttctttc caattccaaa taccgataac tagcgaaatc
    22141 gtaaagatag acaaactatc ccagggagcc ggaatataaa aggctccttc ttgtatgaag
    22201 cttgccattc ctacatatcc taaaacaact agaagaacta tagtcccaac aacaatgtaa
    22261 gtgccaattt tcattttagg agaatcttgg actaaacttc ttcgtaaaat tgtggccaca
    22321 agtccaaatc caatcagaaa aataagaagt tgccctaaaa atgtgagcaa attgactgtt
    22381 aagagaggac ctttagaaaa atcacttagt agttgataat aacgtaatac cgccaggaca
    22441 agaattggcg tcaaaaggga ctctttgata gaactgcgag gtgctccctt gagaatctct
    22501 ttcattattt ttttaggatt cttacctaga taatcctctg cactcatgcc atctcgttct
    22561 gcttctgaga aatctagcat catcaaatag atctgctctc tgagatagtc ttcatcatag
    22621 agaaatccag caagattaaa actttcccac aactcctcaa aatacttttg attctcctca
    22681 gaaaactcat gtagcaaagc gcttgtttct tcgtaatact tcattttctt catggtttaa
    22741 cccccattct taatcccttc tactttttga ctcaaatcgt cccattgttg ccaaaagact
    22801 gagacacgct cttctccttc tttcattaat gaaaaatact tccgatctgg accatctggc
    22861 gacgggcgca tgtcgcctct tatccattga tttttttcta acttttgcaa caaaggataa
    22921 atagttcctg gaacgatagt atcaaatcca gcctctcgca aagtctgaac caactcataa
    22981 ccataccgct ctttttgacc aatcatatcc aagacacaac cttcaagaac accttttaat
    23041 agctgagttt ctttcatcac ttctcccttc taatctattt tgtaatacct actagtaact
    23101 tcacctatag tatattactt ctacactagt ttgtaaagca taatagttaa tactcttcga
    23161 aaatctcttc aaaccacgtc agcgtcgccc taccgtatgt atggtt
//
LOCUS       DAVHSY010000030        21591 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.031, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000030 DAVHSY010000000
VERSION     DAVHSY010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21591
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.031"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(267..1463)
                     /gene="tuf"
                     /locus_tag="VVR43_001453"
     CDS             complement(267..1463)
                     /gene="tuf"
                     /locus_tag="VVR43_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU6149803.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2374..3243)
                     /locus_tag="VVR43_001454"
     CDS             complement(2374..3243)
                     /locus_tag="VVR43_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU6149804.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3466..3987)
                     /locus_tag="VVR43_001455"
     CDS             complement(3466..3987)
                     /locus_tag="VVR43_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6149805.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKEDKK"
     gene            complement(3959..5050)
                     /locus_tag="VVR43_001456"
     CDS             complement(3959..5050)
                     /locus_tag="VVR43_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU6149806.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTIITVRMLRKSGSQNSNLY"
     gene            complement(5161..5415)
                     /locus_tag="VVR43_001457"
     CDS             complement(5161..5415)
                     /locus_tag="VVR43_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149807.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5755..6288)
                     /locus_tag="VVR43_001458"
     CDS             complement(5755..6288)
                     /locus_tag="VVR43_001458"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU6149808.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLERFFKTR"
     gene            complement(6275..6490)
                     /locus_tag="VVR43_001459"
     CDS             complement(6275..6490)
                     /locus_tag="VVR43_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6149809.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            complement(6457..6600)
                     /locus_tag="VVR43_001460"
     CDS             complement(6457..6600)
                     /locus_tag="VVR43_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEU6149810.1"
                     /translation="MAYSTDFKQRALDYIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            6834..8552
                     /locus_tag="VVR43_001461"
     CDS             6834..8552
                     /locus_tag="VVR43_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU6149811.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            8663..9010
                     /locus_tag="VVR43_001462"
     CDS             8663..9010
                     /locus_tag="VVR43_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU6149812.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9289..10125)
                     /locus_tag="VVR43_001463"
     CDS             complement(9289..10125)
                     /locus_tag="VVR43_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6149813.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGSRKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10138..10767)
                     /locus_tag="VVR43_001464"
     CDS             complement(10138..10767)
                     /locus_tag="VVR43_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6149814.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(10777..11418)
                     /locus_tag="VVR43_001465"
     CDS             complement(10777..11418)
                     /locus_tag="VVR43_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6149815.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11564..12793)
                     /locus_tag="VVR43_001466"
     CDS             complement(11564..12793)
                     /locus_tag="VVR43_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU6149816.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALHIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(12783..13949)
                     /locus_tag="VVR43_001467"
     CDS             complement(12783..13949)
                     /locus_tag="VVR43_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU6149817.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14093..15106
                     /locus_tag="VVR43_001468"
     CDS             14093..15106
                     /locus_tag="VVR43_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU6149818.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15151..15570)
                     /locus_tag="VVR43_001469"
     CDS             complement(15151..15570)
                     /locus_tag="VVR43_001469"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU6149819.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(15581..16987)
                     /gene="atpD"
                     /locus_tag="VVR43_001470"
     CDS             complement(15581..16987)
                     /gene="atpD"
                     /locus_tag="VVR43_001470"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU6149820.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTISMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17073..17951)
                     /locus_tag="VVR43_001471"
     CDS             complement(17073..17951)
                     /locus_tag="VVR43_001471"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU6149821.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(17967..19472)
                     /locus_tag="VVR43_001472"
     CDS             complement(17967..19472)
                     /locus_tag="VVR43_001472"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU6149822.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19487..20023)
                     /locus_tag="VVR43_001473"
     CDS             complement(19487..20023)
                     /locus_tag="VVR43_001473"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU6149823.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20023..20517)
                     /gene="atpF"
                     /locus_tag="VVR43_001474"
     CDS             complement(20023..20517)
                     /gene="atpF"
                     /locus_tag="VVR43_001474"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU6149824.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(20531..21247)
                     /gene="atpB"
                     /locus_tag="VVR43_001475"
     CDS             complement(20531..21247)
                     /gene="atpB"
                     /locus_tag="VVR43_001475"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU6149825.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21282..21482)
                     /locus_tag="VVR43_001476"
     CDS             complement(21282..21482)
                     /locus_tag="VVR43_001476"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU6149826.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         6464 a         4660 c         3920 g         6547 t
ORIGIN      
        1 tacaacctaa aaacagtgtt ttgagcagtc tgcagctaac tttctataac aaaatgaaat
       61 aagaacaaga caaatcaatc aagataatca aatcgatttc taacaatgtt ttagaagtag
      121 atgtgtacta ttctagtttc aatatattat agtttgctct ttgattttca ttgagtatta
      181 gttcaatatc taaaaaaaga accttgccaa gcaagattct tttagtgtct gacttaaata
      241 attgttcttc tgggaactaa atcgaattaa gcttcgattt ctgtaaccat acctgaacca
      301 acagtacgtc caccctcacg gatagagaat gtagtacctt gttctacggc gattgggtga
      361 atcaactcaa cgtcgattgt cacgttatca ccaggcatta ccatttcagt acctgctgga
      421 agttcgattg aacctgtaac gtcagtagta cggaagtaga attgtggacg gtagttgttg
      481 aagaatggag tgtgacgtcc accttcttct ttagtaagga tgtagacttc acctttgaat
      541 ttagtgtgtg ggttgattga acctggttta gcgataactt gtccacgttc gatttcatca
      601 cgttgaacac cacgaagaag gacacctacg ttatctccag caagaccttc gtcaagttgt
      661 ttacggaaca tttcaacacc agtaacaact gctttttgag tttcttcttt gataccaaca
      721 atttcgattt cgtcgttgac tttaacgata ccacggtcga tacgtcctga agcaactgta
      781 ccacgtccag tgattgagaa tacgtcctcg actggaagaa gcaatggttt gtcagtgtca
      841 cgttctggtt ctgggatata ctcatcaact gtgttcatca attccataac gatgtcttcg
      901 tatttagagt caccttcaag agctttaagt gctgaacctt ggataactgg aagatcgtca
      961 cctgggaagt cgtattctga caataggtca cggatttcca tttcaaccaa ttcaagcaat
     1021 tcttcgtcgt caaccaagtc aactttgttc atgaagacga taaggtgttt aacaccaacc
     1081 tgacgtgaaa gaaggatgtg ctcacgagtt tgtggcattg gtccgtcagt tgaagctact
     1141 acaaggatag ctccgtccat ttgagcagca ccagtgatca tgtttttaac gtagtccgcg
     1201 tgtcctggag cgtcgatgtg agcgtagtga cgtttttcag tttcgtactc aacgtgcgca
     1261 gtgttgatag tgataccgcg ttcgcgttct tctggagcag catcgataga cgcatagtct
     1321 ttaggttggt taactgatga aggcaagcga cgtgccaaaa cagttgtgat agctgcagtt
     1381 agggtagttt taccgtggtc aacgtgtccg atagtaccaa tgttaacgtg tggtttacta
     1441 cgatcgtatt tttcttttgc catttgagta aaagcctcca ataaaatata ttttatagat
     1501 agacagtagg caatacagtc taactttcct tactatttta tcaaatttca gctaaattgc
     1561 aagtgtttta caacgttttt gtgaattatt cttggtaaaa atttaactaa ttaatagaaa
     1621 gtactaaata gacttatcct tcaaggagtt ttcagcatta tccatccact cacttgctga
     1681 aaatgtaaac agtctctggt ttatatagta aaatgaaaca agaatagggc aaatcgatca
     1741 ggacagtcaa atcgatttct aacaatgttt tagaagtaga tgtgtactat tctagtttca
     1801 atctactata caacctcaaa actgtgtttt gaacaacctg cggctagctt cttagtttgc
     1861 cctttgattt tcattgagta taaaattgca gataaaacga taacaatcat aggactcagc
     1921 agagtcaatg taggtcgaag aatagccccc ctaatcgctt attttatagc aaaatgaaat
     1981 agaaactgaa cattttgttg aggaaggtaa atcaattcct cacaatgttt gagaaagaag
     2041 gggggactat tccaacttca acccactata aagcagactt acaagatagg gaacccatct
     2101 ccgataatat atagtagaat gaaaactgca caatttgatt ggagaattca aaccaatttc
     2161 taacaatgtt ttagaaacaa gggtctatta tttcaactgc aacctactat agcccattga
     2221 agctggaata gcccactgag acttctaaac cactgctgga gaggagtttg tttagagttt
     2281 ctttcatttc cctaaaaaat caaaaagaga gaaccagtct gatcctctct tacttataga
     2341 tggtgctcac tcaaatgtta aaggagctat ttcttagaga taaaggaatt tgaatacagc
     2401 tactgccgca attgctgctg cgataggtgc tactactggt acccaagaat accaccattt
     2461 tgaatcgcct ttatgctcac caagaactga ttttggaagg aaagcatgaa ggagacgtgg
     2521 tcccaagtca cgggctgggt tcaaggcagg tcctgtaggt cctccaagtg atgttaccaa
     2581 agccataacg aggaatccaa gtgccaagtg agccacagaa agtcctgaag cagtgtgtgg
     2641 agccacctgt gctttaatag ccaagtcaga aaaatcaact gtttgtcctg cttctattgc
     2701 cttttgtttc atgaattgaa gcacttcagc accaaagaag tttttagtca aaccaagagc
     2761 tgcaaagaac aaaacaaatg aaccaacaaa ctcattaatc aaaccattga cagttgctgc
     2821 atagcgactt tcttttgtac catggtcaat acttgaaata gttgagaaag ttcccaagat
     2881 gttatttggt ttttcagttt tcaagtagaa tggacggtat gttgccacaa ctaaggcttg
     2941 gccaaagata gcccccaaga cttgcgcgat aatgtaaggt accacttgtg cccaagggaa
     3001 aagaccgcta actgcaagcc ctagagtgaa agcagggttg atgtgattcc cagatacgtt
     3061 accaaacatc aaggctggga tcataacccc cataccataa ccaacagcga tgacgatcca
     3121 gccactttgg tgacctttcg tacctttaag ttcaacgttg gcaactgcac cattcccaag
     3181 aatgatcaaa atggcagttc ccaaaaattc agtggcatac ttcagtgccc atgtgaaatc
     3241 catttgctag attctcctta aaatttttta gatattcctt attttatcaa tttttaccct
     3301 atttagcaac tgatttctgg aaatattttt aaaaaaatag gattcatagt ttcccagttc
     3361 aacgtacttg taagcgtttt tattcttcac gaaagacctc attctcaaaa ccaggaaaaa
     3421 gcccacatct gtgatctttt ccttgttcct agattctaaa atctattatt ttttatcttc
     3481 ttttttcttg aagaatccta atcctagacc agctaacaag gtcatgatac cagcactagc
     3541 caaggtagca ttagcttctg tacctgtgtt tggcaattcc tctctcttac ctgtctcata
     3601 agtcggaact tctgggtctg gattcactgg agtttcagtt tttggagtac ctggttctgg
     3661 agttggttta tctggtgttg ataaacggtc ataccttacc gttatttctt tatcactaga
     3721 gtctgacgta acttcttgtg attcaactgt tggaatatct ggatctttgt acttgtcaat
     3781 cttaccagat ataacctcgt cccagtttcc tgttgtccat tcaccgtagg ttacaactcc
     3841 cgtgaccttg ttctcagttt ttgtacggct taaggttaca ggttgaacaa catcttcttt
     3901 tacattttgg ttcgtaactt tatcaacgta atgaatgata cgcgttatag tcttcgtctc
     3961 agtagaggtt gctgttttgg gaaccacttt tcctcaacat tctcacggta ataatagtca
     4021 actgttgcac cgtcttctgg tacgcatttg caggagttgc taccaaggtg tatgttgttt
     4081 tccttgtgat aactcggtct tctttgtcct cagttgttgt tttcccttca atagtttttg
     4141 attctgtggt atactcagaa cctatcgcta aatcagcttt tataacagac tctgccaact
     4201 tctcttggct accttcttta tagtaattgg ctgttactgt agcagtggtt ggcgcttcgc
     4261 tttctctata aactaaggtc actgttctac cttcgcttac aatattccca gttaaacttg
     4321 cagaatttgt atctgcttct ttaaaagtat aatattttcc gtcagtagta gtcatgctac
     4381 tgagtttttt atctgtgaca ttgtagctgg taccaatcag ttgtttttta ttggtaatgt
     4441 aggttccgtc actttctttt tctccaattc cagtatcatt tttcaatgat agcaaacgcc
     4501 cttgttcatc aacatagcga actttcacat tttctgagat tagttctgcc aattctgagg
     4561 tttttttctt tttcttgatt tcttcggtta ttttcccttt ctcttcttcg ggaatattta
     4621 gttttggaat gattttttca acaacggttc gtgatggttc cacagtatct tggatgactg
     4681 aaaagtcagc tagaattggg agattatact gaacacggtg actttgagtg tttactccta
     4741 ctctttcatt attctctgaa aatacttgta cggtataaga aacaacatct tttcctaata
     4801 gaacatcccc agtagagaaa tagccgcctt ttcctagttt gctatctcca gagcccactt
     4861 ctttcctaat cttatcagat agttttttac cagtcagtac attcgttcgc acaatccctt
     4921 tgtctacccc tacaaagtgg gagaactttt tgaactcttc agaaccagat ctagcccaac
     4981 cattattaag ggcatttgct tttgtatttg tattctctct caaaagtttg gcgattagaa
     5041 ttatattcat cggcacttag agttgctgct atatctgact cttgaatacc aacttcctta
     5101 ctaccatttc tagcggcagt atatgtgtat ttatttgttt ctacttctag ctgattatcc
     5161 ttaacatgat aggtaatttt ctcctggtat aagagtcttc agtagtttat atgctctgtc
     5221 atcatcttta gctttagaag cagctgagtt tagccaagtt ggggtattag gagtatcttt
     5281 atcagcctgt ttcaagacat tattcaagtc atttgctagc ctattggttg tcctcactgt
     5341 gaaagttttc ttccagtctg aaccactttt attagactta gatatgctca tgaaatcctg
     5401 gtcaacattc aacacaatat cgccttgttt tttagcatct tccgttgctt ctgcttcaaa
     5461 ttgatcatgg aatttttgtt gctctggtgt atagtttttt tatttacacg atttaatgta
     5521 ctatttttta ttttagtatt aagaactcca ttaatacgat ttttaaactc tgcttcaaaa
     5581 aatcccttaa tttgttggtg cgcaagttca acattcaaac ctttcttata caagtcttca
     5641 ttctgaacga tttcggctac acggtgaatg gtttgatcgt ataccgtctt ctcttaacca
     5701 gcagtatcct tagttttaat gactactcga taagttcctt tagaaccgtt atagtcatct
     5761 agttttaaaa aagcgttcca aacattcaaa aatagttgga acttccctta ataaatccgt
     5821 cactttcttt ttcaagatag cccaagcttg ctcaatagga ttcaaatccg gtgaataagg
     5881 tggtagaggt aagaaaaagt gtttatcttg gatgcagagt tcatccaaaa tgttcttggg
     5941 atgaaaacta gcattgccca tgacaataac atgaggtgtc ttcaaagcag gtaggagttg
     6001 cgttttgaac cactccacaa agaaatcgct tgtcatgctt ttcttgtaaa tcatgggagc
     6061 tataaactct ccgtctactt gtcctgcaac aattgaagtt cgctcaaaac gacgtccgct
     6121 aatcttttca tagactttct cccctctagg agcccctgca taaggacgat agaggtagcg
     6181 gtcgattcct gtttcgtcaa tatatacgat tggtaaatct tttaggttat ccaaaatatc
     6241 aagaaactca gcgactttct ctggctcttg ttccttaaag ctcgtcatct ttttttaaag
     6301 tgaccttaat ctgctttaaa gctgcccata ctgaaggaac agcacaatca aaatgtgccg
     6361 caatttcccg taaaaaagca tctggatgag cctctacaaa ggctttcaat tcctctaaag
     6421 gaatctttcg gtttttgacg actcgctttt tcctctctat gtgtccttgt tcacatcttt
     6481 cttttcccac gtgaagagag ttctgacgcc aacaccaaaa aacttggctg cctcgacatg
     6541 gctgtgcccc tctttgatgt aatctaatgc tcgctgttta aaatcagtac tatatgccat
     6601 agctttatta taatatgctt gtttaaaact aagcaactat atcaatgttt tgttattaga
     6661 agacttactt tttttactga aatcgaattt ttcctaacct caacatcata taaccccaaa
     6721 attcaatctg acctggtttg aagagatgtt cgaagcagat aaggttttac taaaactaaa
     6781 aaaaatgata taatcaaact gattaaatgt tttaaaaata aaggagaatt tgaatgtctt
     6841 accaagaaaa ttaccagaaa tgggttgatt ttgtggagct tcctgactac cttcgtcaag
     6901 atttggaaaa tatggacgaa aaaactaagg aagatgcctt ctatacaaat cttgaatttg
     6961 gtactgcagg tatgcgtggc ttggttggtg ctggtacaaa ccgtatcaac atctacgttg
     7021 ttcgccaagc tactgaagga ttggctcgtt tgattgagtc aaaaggtgga aacgagaaag
     7081 aacgcggtgt agcaattgcc tacgatagcc gtcacttctc acctgagttt gcctttgaat
     7141 ctgcggcagt tcttgctaaa cacggcatca aatcttacgt atttgaaagc cttcgtccga
     7201 ctccagaact atcatttgca gttcgtcatc tcaactgttt cgcaggtatc atggtcacag
     7261 ccagccacaa ccctgctcca tttaacggtt acaaggttta cggtgaagac ggtggacaaa
     7321 tgcctccaca cgatgcggac gctttgacta cttatatccg tgcaatcgaa aacccatttg
     7381 cagttgaagt tgctgatgtg gaaactgaaa aagcttctgg cttgattgaa gttatcggcg
     7441 aagctgttga cgtagaatac cttaaagagg ttaaggacgt aaacatcaac ccagccttga
     7501 ttgaagaatt tggtaaagac atgaagattg tctacacacc acttcatggt actggtgaaa
     7561 tgttggctcg tcgtgctctt gcccaagcag gatttgactc tgttcaagtt gttgaagcgc
     7621 aagcaactgc tgacccagac ttctcaactg taacatctcc aaacccagaa agccaagcag
     7681 cctttgccct tgctgaagaa cttggtcgtc aagttggtgc agatgttctt gtcgcaactg
     7741 acccagacgc tgaccgtgtt ggtgttgaag ttcttcaaaa agatggtagc tacctcaacc
     7801 tttcaggtaa ccaaatcggt gctatcatgg ctaaatacat cttggaagct cacaaaaacg
     7861 ctggaactct tcctgaaaat gccgctctct gcaaatctat cgtttcaact gacttggtaa
     7921 cgaagattgc tgaaagctac ggcgcaacta tgttcaacgt cttgacaggt ttcaaattta
     7981 tcgctgaaaa aatccaagaa ttcgaagaaa aacacaacca cacttacatg atgggatttg
     8041 aagaaagctt cggttacttg attaaaccat ttgtacgtga taaagatgcc atccaagccg
     8101 ttcttgtcgt tgctgaactt gctgcctact accgttctcg tggtttgaca cttgctgacg
     8161 gtatcgaaga aatctataaa gaatatggct actacgcaga aaaaacaatc tctgttactc
     8221 tttcaggtgt cgatggtgct gaacaaatca aagcgattat ggctaaattc cgcaacaatg
     8281 ctccaacaga atggaacgca acagctatca ctgtcgtaga agacttcaag gcacaaactg
     8341 ctactgttgc tgacggtact gttacaaact tgacaactcc tccaagtgat gtgttgaaat
     8401 acacacttgc tgacggttca tggattgccg ttcgcccttc aggtacagaa ccaaaaatca
     8461 agttctacat tgcagttgta ggggaaacca acgaagaatc acaagctaag attactaaca
     8521 tcgaagcaga aatcaatgca tttgtaaaat aaagacctat aaaagatgag accaaccaac
     8581 ctcatctttt ttcgtatcaa atctaagcaa ttttagaaac tttatggcat actagactta
     8641 tcaatgaaag cgaggtaatc tcatggaaca atttttagat aacatcaaag accttgaagt
     8701 cactacagtt gtgcgtgcgc aagaagctct tgataaaaaa gaaactgcaa ccttctttat
     8761 cggtcgcaaa acttgccctt actgccgtaa atttgcaggt acattgtcag gtgtcgtagc
     8821 tgaaaccaaa gctcacattt acttcatcaa tagtgaagaa ccaagccaac tcaatgattt
     8881 gcaagcattc cgctcacgtt atggaatccc aactgtacca ggttttattc atattacaga
     8941 tggacaaatc aacgtccgtt gcgactcttc aatgtcagca caagaaatca aagatttcgc
     9001 aggattgtaa aaaatcagct aacaagtctt aaaatcacaa aaacgcataa tgtaaggtgc
     9061 aaaaaccttg atattatgcg ttttattgtt cctaaaacag ttacatcagc atttcattac
     9121 agaacatttt aattttggaa gtcaaatcaa tttttaacaa tgttttagaa atcacagtgg
     9181 gctattccat attcaattat ccagattcaa tcgctattat cgttttccta gattacaaaa
     9241 aaaactacgt tttgctaatc aaaacgtagt ctcagccact attttatctt actgtccttc
     9301 ttttacttct ttggttgcta catcttctcc aaaccatttt tggctgattt cttggaactt
     9361 gccgtccttg taaagactag aaaaagcttc atttatcttc ttaaccaagg ttgtatcttc
     9421 cttacgggat ccaaccgcaa aagcttctgt ttctagtcca actgtaaaga cattataatc
     9481 gtttaaaaca ccttctgctt ctaaataata gtttgcatag acacggtcaa tcaatagacc
     9541 atcaattcga tcgtttttca aatcaatcaa ggcttcatta aaggtttggt attgattcgc
     9601 ttccttatta gcgacaatat tcttcaaaat ttctggattt gcttcaaagt ccgcataacc
     9661 agatgaacca gcttgagctc ctaatgtctt tccagtcata tcctttgcag tcgtgatacc
     9721 agatgatttc ttcgtaacca atacctgctc attcttcata tatgagttac tgaaagccac
     9781 cttttcacgg cgttcgtctg tagcggaata gccattccaa atcagatcaa tcgttccttt
     9841 tgtcaattca gcttctttca aatcccaatc aatcggttgc caatttaccg tgattccgta
     9901 tttttcaaaa acagctgtag ctaaatcaat atcaaatcct gcataagaac catctttctg
     9961 agcaaatccc attggaacaa aagtactatc aaatccaata gtaatagact tgttagactg
    10021 gtactttgac caattatctc cactagtttc gctagaattt ttcccacaag ctactaagaa
    10081 caaagcagtc atcagactga ctaatacaag catccatttt ttcatccatt tttcctccta
    10141 tttaggttct actttcaata atacatctgc gatattttca gcaaactgca aatcatgggt
    10201 aaccacaatc tgggtcatcc caagttccct attttgcaag attagcttct ccacttccaa
    10261 acgtaattct ggatccaggg cagaagttgg ttcatcgtag ccaatgattt ctgggtcaat
    10321 catcatagca cgcgccaaag ccacccgctg cttttgccca ccagatagtg agaaaggata
    10381 ggcctctgcg tgtcctccta gtcctaactg ttccaagagc ccactcgcct tcttctcagc
    10441 ctcttcctgc ttcattccca tggtcttcac aggcgataaa gtcaaatttt ccagaactga
    10501 tagatgagga aatagttgaa aatcttggaa gacaaatccc agtaggttgc gcttctgcaa
    10561 ttcatccagc tctaaaggtt gtccattata aaagatttgc cctgaatcaa tggtttcaag
    10621 acctgcaagc atacgtaaaa gagttgtctt acctccacca gaaggtccaa cgatagccag
    10681 gatttgcttt tcaggaatac ttagactgaa atcagacagg atttgtttgt ctccaaagac
    10741 tttattgata tttcgtaatt ctaacatagc tgccccctat ctataataac tatacttctt
    10801 ctcaactttt ttggaaataa ttgtcacaat cccaattaaa atcaagtaaa tggctcctgc
    10861 caagaacata ggaaccagac tagcatcgcg gttagcagct gttcgactag ccaagataag
    10921 gtctgaaatt ccgagagcat agaccaaaga agtatccttg accaaactca taacttcatt
    10981 aaagacacta ggaagaacga tcttggtcac ttggggcaag ataatatagc gcactctgtc
    11041 aaaagggcta aacttcaaga ccttggcagc ctcatactgt cctcttggaa tagtgtcaat
    11101 tcccccacgg aaaatttctg caaagtaagc tgcatagttg agaacaaagg caataatagc
    11161 tgcaggaagg cggtctaaac gaatcccaat acttgggagc acataataga taaaaatcag
    11221 ttgcaagagt aagggggttc ctcgcataac ccagatgtaa atgttaatca gataatggag
    11281 gggcttccaa tggacttgca aggcaaaggc aatcaaaacg cccaacggaa tcgaaaatag
    11341 caagaccagt gcaaagacct gtacagtcgt gctcgcacca ttcagtaaac tcggtaatat
    11401 ctcaaataaa taagacatac tgcacctcct aaaagtaatt gttcctatta tagcatgaat
    11461 aaacaagatt accaagtatt tttgtaaaaa gattctacca tatacaaata aaaaccgtag
    11521 ctatcaaaag agataaacta cagttctata tgtttaaaca ttcttacaat ctctcaaaca
    11581 gttcttgcat ttgcacatca tctggaacca gttttaagta agtgtgagca tggacttttg
    11641 cttcttcaaa atgtcccaat tcacgcaaga gatagatata gtgttccaga aattctggat
    11701 tgtccttcaa atctcctgtc aactcttgat aatgctcata agcagtatcc aaatcgtcca
    11761 tttcttgata agaacgagca atcatccact tggtcaaaag attttctggc tcctcactct
    11821 gcaagtctag aatatcctca taacgctcct gctccagata aatagtggct aaacgaagca
    11881 agatttcttc tgtatcctca gcgtcttctt ttgcagtaag gagataattt tctgcaccac
    11941 tagcatcatg caattcataa gaaaattgtg aagcagctag caagaggcga gtttcaaagg
    12001 gatttttctc taatccttgc ttagcgatat gcagggcttc ttgaacttga tgttccttat
    12061 gtaaagcctg actgtaccca tactcatagc cttcaaagtc aggagaaatg gtatcaagct
    12121 gcttaaagta gagggtggct ttttgatatt cttcttgatc aaaataaaga ctggccaact
    12181 caaaagctgt taagtcatcg tattctaact ccagggcttt ttctaaaaac tcagtagccg
    12241 tttcaaattt ccctaactga gcataggcaa agccaattcg ttgataggtg gaaatgcccg
    12301 tttgctcata aatcgagcga ttatctaact gggcataggc ttgaatagcc gcttggtaat
    12361 tttccaactc actatccaac tctgccaaac ccaatatcaa gagagaatcc tctgagtagg
    12421 tcaaggcctc caataatttc tcacgtgcca catctgtcaa accttccagc tggtaaaggt
    12481 ctgccttcaa aaccaaagac gagacatacc agtcactgtc agcttggatt tcctcaagat
    12541 aggtaaaggc ttcttctatt tgaccatcct cgctagcaat tgcagctaga ttaagatgaa
    12601 cctctggaaa atcctctaca attttcaggt aaatttcctt ggcctgagga tagaaaccaa
    12661 tcccttcaag ataagttgcc aactcataca gaagatcact tgaatcattt tctaaagctt
    12721 tggcgaaata atgctcagcc ttagttaaat cttgctcctc caaagcctgt aacatctgtt
    12781 gactattgtt cactcttgac ttcctcaccc tctaattcat atagaccact gactacctta
    12841 taccattcga aaatggctga aatgacaacc ttagcagagg cataaactgg aataccaagt
    12901 aaaactcccc agataccaaa catagatcct gaagttaaca aaacaaagag aacattaata
    12961 gggtggatgt ttaattgact tcccaaaatc aatggagaga caaaacggcc ttcaatagtt
    13021 tgttctacaa taaagacaat cactactttc aaaagcatga ctggaccagc aatcaaaccc
    13081 aatactaggg caggaagcat ggctagaaag ctaccaagat aagggaccag atttaaaata
    13141 ccagcagtaa cccccagcgt aaccgcatag cgtagaccaa taatcttgaa gaagatgata
    13201 aacattactg ctacaataat agccactgtc acttgccctc gaacatagtt ggacaactgt
    13261 tgattcacat ctgatagaac ttgtccaaca ggttccttca attttcttgg aatgaattgg
    13321 gtcaaatagt tacgcaagcc tttcccatca cgcaagagat aaaagagcat gaaaggaacg
    13381 ataatcaagg caacaatcac ttgagaagcc ccgctaataa aggcactcac ccagttgact
    13441 gcctgagatg aaaccttact tgccaaaact gtagcctggc tagaaaaatt ggtcaaaact
    13501 tgctctaatt gaggtctgaa atcatctggc agatgctggg ctaccaatcc attaacaatc
    13561 ctatctatat cttctaagta aacaggaacg tttcttgcaa aggtcaaaac ctgacgttgc
    13621 agatttggaa tggcgactgc caagccccaa atgataaaga gagcgatgat aacaaagaca
    13681 atagtgatag ctataacacg attaacctta tgcttctcca tccaatcaac aataggattc
    13741 aacaaataat ataacaaacc agacaaaatg actggcaaca tcacaactgc taaaaagtct
    13801 aaaacaggtg aaaatagaaa actaatctta cttaaaataa aaagattcaa tcccaataat
    13861 aaggttacta aaaataccgt aattgccttg ttatctaaaa accacttgaa aaaccaagat
    13921 aggctaaaat gtttctcttt ttgctccata aatacttcct ttctattgtt ctctcattat
    13981 accatttttg aaacaaaata actctttttt aaagtgctta catctaattg gatgtcttta
    14041 atttgcttgt ttttgtgata taatagtctt atctttacat agaggtatag taatgaaaga
    14101 aactgtttat tttggaactt atacacgtcg tacttctcaa gggatttaca aggcagactt
    14161 tgatacagaa actggtcagc tttcaaatct agaacttttt gcagctgagc caagtccaac
    14221 ctaccttgcc tttgaccagc accaacattt atacactgtt ggtagccaag acgataaggg
    14281 gggaattgca gcctatcaaa ctgacgggac tgtgttaaat catgttgttg aagaaggagc
    14341 tccccactgt tatgttgctg tcgatgaaaa gcgtgatttg gtttacgcag ccaactatca
    14401 caagggacaa gtccttgttt ataaacgcca ggaagatggt agtcttctac ttagtgatat
    14461 ggatcaacac agtggccaag gtccacatga aaatcaagct tccccccatg ttcactatac
    14521 agatttaaca cctgaccact atctagtgac ctgcgacttg ggaactgacc aagtcatcac
    14581 ctatgatctc gatcaagaag gaaaattatc taagctctat acctatcaca gcaagccagg
    14641 agcaggctca cgccatatca ttttccataa ccactataaa atcgcttatc tcatttgtga
    14701 actcaatagt actatcgaag ttttaatcta cgatggcgtt ggcgaatttg tacgtatgca
    14761 ggttatttca actttaccag aagcttacga aggctttaat ggaaccgctg ctattcatct
    14821 ctctaaagac ggtaaatacc tctacgcttc taaccgtggc catgattcta tcgcagtata
    14881 taccatcctt gcggacggta gcttagagtt attagaaatc gttccaacgc atggtcagac
    14941 tccacgtgat tttgatttga cacccgacca aaaatttctc attgttgtcc atcaagactc
    15001 tgacaatgca actgtcttta aacgtaattg tgacaatggt cgtctagcag aactctccaa
    15061 cgacttccat gttcccgaag cagtctgcat ccgttttgct ccttaaaaca ccataaaaaa
    15121 tgaacttggt attttcaagt tcattttttc ttatagtcta tttccgacat taatacggtt
    15181 aatggcacgt tgcaaagcaa tcttagcacg acgttcttgg tcaatcaaat gtttgtcttg
    15241 tgcttcttca attgcacgtt ctgcacgaag tttggcacgt tctgcacgac tgatatcgat
    15301 atcacgagca cgttctgcag agtcagcgac gattgtaatc atatcattgg caatttcaat
    15361 aacgccaccg tttactgcaa tccagttcac gtgatcttta tcatcgatac gttttacctt
    15421 tacttcatca actgctaaaa ccgcaatcat attttcatgt cgtggcaaga tccccatctc
    15481 accatccaga gttcgaaccg atacatagct ggcatggtga tcatagacga gaccatctgg
    15541 tgtcacgatc tggacagtta actgagccat aggtcacctc ttaaaatccc attttttcag
    15601 cttttgcaat cacatcttcg atagaaccta caccacggaa ggcatcttct ggcaagtggt
    15661 cgtatttacc atcaaggatt tccttaaagc cacgtacagt ttcagcaact ggaacataag
    15721 aacctggctg accagtaaat tgttccgcaa cgttgaagtt ttgtgacaag aagaactgga
    15781 tacgacgggc gcgagcaacc aaggtctttt cttcatcaga aagctcatcc ataccaagga
    15841 tagcaatgat atcttgcaat tcatggtaac gttgaaggac acgttttact tcagcagcaa
    15901 ctgcatagtg ctcttctcca acgatttcag gtgccaaggc acgtgagctt gaagcaagtg
    15961 ggtcaacggc tgggtagata cccaattgta ccaatttacg ttccaagttt gttgttgaat
    16021 ccaagtgagc gaaggctgtt gctggcgctg ggtcagtata gtcatccgct ggcacataga
    16081 tagcctggat agaggttaca gaacccttct tggttgatgt gatacgttct tgcaattgac
    16141 ccatttccgt agcaagtgtt ggttggtaac caacggctga tggcatacga cccaaaaggg
    16201 cagatacttc tgaaccagcc tgagtgaaac ggaagatatt atcgataaag agaagcacgt
    16261 cttggccttc cacatcacgg aagtattcag cgattgtcaa accagtaagg gcaacacgca
    16321 tacgtgctcc tggtggctca ttcatctgac caaagaccat ggctgttttc tcgataacgc
    16381 ctgattcttt catttcccag taaaggtcat tcccctcacg agtacgttcc ccaacaccag
    16441 taaatactga aataccaccg tgctcttggg caatgttgtg aatcaattct tggattaaga
    16501 cggttttacc aactccggca ccaccgaaaa gtccaacttt accaccttta aggtaagggg
    16561 caagaaggtc aataaccttg atccctgttt caaggatttc agaagaggta gacaactcat
    16621 caaaagttgg agctttttta tgaattggct gacgctctgc gtcttctgta aaaggagctt
    16681 ccaaatcaat ggtatctccc aaaacgttga agacacgtcc caaagtttct ttacctactg
    16741 gtacagagat tggacgacct gtgtccaata cttccattcc acgagtcaac ccatctgttg
    16801 attccatgga gatagtacga accataccat ctcctaactc caaggctact tcaaggacga
    16861 tttttgtttt tctttcgtca tttttgtaga cgacaagtgc attgttaatc tcaggaagtt
    16921 tttcccctgc tgcaaacaaa acgtctacaa cgggaccgat aacctgagca attttacctg
    16981 aactcatctc cttctcctat tctatataag atactgtcgg ttcctagctc aactaggtcc
    17041 taagttcatt ttcatacgag ctggactaga gcctattcta aggcactagc acctgctacg
    17101 atttctgtaa tttcttgtgt aatcgccgcc tgtctggcac ggttatactg aattgtcaaa
    17161 tcattgatga ctttcttagc attatctgtc gctgtttgca tggctgtcat acccgcagca
    17221 ttctcagctg tcttggcatc gataatggca ccgtaaatca tactttctgc aaactgaggc
    17281 aacaactgct ccagaatttc ttctcggctg gtttccaatt caaaagtcaa gctgtactct
    17341 tcatccgcct catttggatc caagtcaaca atcggaagca tttgttccac acgcatttga
    17401 ctggttagcg tattgacatg gtggttgtag caaacataaa gctcatcaaa gagttcattt
    17461 tggtacattt caacagtttt tgaaataatc ttacgaactt gatcaaagct aggttggtct
    17521 gccaagccac gtaattcata aagtggttga ataccgcgag ccttaaagaa atcagctccc
    17581 atcccaccga tacagatcat ttcaaaacct ttaccgtctg ggtggtattc ttctttcaac
    17641 tccataacag ctttcaaaat agaggaatta taacctccaa ccaaaccgcg gtctgaagtg
    17701 ataacgatat agcctgtctt cttcacagaa cggctaatca acatcggatt agttgaagca
    17761 ccagctccat taccatgaag gatatctgtc aaaagtttac gcactttctg agcgtaaact
    17821 tggaagttgc gagcagcttc ttcagagcga cctaacttag cagccgatac catttgcata
    17881 gcattagtga tttgactcgt attttttgtt gaggcgattt ttgttttaat atcatttaga
    17941 gacactgcca tctgacacct ctattcttat tggaagctag attgattgag aaactctgta
    18001 atcgcagcat ccaagactgc ttcttctggc aagtcttttg tatcacgaat ggtttccaaa
    18061 atctctggat gttgagcatc aaagaaggca tggaactctt cctcgaaacg aacaatatca
    18121 tctactggaa cagtatccaa gaaaccatgt gtcaaagcat aaagaatggt tacttgtttc
    18181 tcaacaggta atggtttgtg aacaggttgt ttcaagacct caacggtacg acgtccacgg
    18241 ttcaacttag cctgtgttgc tgcgtccaag tcagaaccaa acttagtaaa ggcttccaac
    18301 tcacggtatg aagcaaggtc gatacgaagt gtaccagcaa ccttcttcat ggctttgatt
    18361 tgtgcagaac cacctacacg agatacagat gaacccgcat cgatggctgg acgaatacct
    18421 gcattgaaga ggccatcgcc aaggaagatt tgtccatcag tgatagaaat cacgttggtt
    18481 gcgatatagg ctgagatatc tcctgcttgt gtctcgataa atggtagggc tgtaattgat
    18541 ccaccaccaa gttcatcaga aactttagct gagcgctcaa gcaaacggct gtggagatag
    18601 aaaacatccc ctgggaaggc ttcacgacct ggaggacgac gaagcaagag cgacagttca
    18661 cgataagcta ccgcttgttt tgatagatca tcgtatacaa tcaaaacatg cttaccttga
    18721 tacataaatt cttccgccat agcaacccca gcataaggag ctaggaagag caatggagat
    18781 ggttgtgaag cagaggctgt cacaacgatt gtgtagtcca aggcaccgta ctgacgaagt
    18841 gtttctactt gcgtacgaac tgttgattct ttttgtccaa tcgcgacgta gatacagatc
    18901 atatcttgat ctttttggtt caagattgta tcaatcgcaa tggttgtttt ccctgtctga
    18961 cggtcaccga taatcaactc acgttgacca cgaccaatcg gtacaagggc gtcaatagct
    19021 ttcaaaccag tttgcaatgg ttctgaaaca gacttacgtt gcataacacc aggagctggt
    19081 gcttctactg gacgagtttt atcagtgtgg atttctccaa gaccgtcaac tggacgacca
    19141 agcggatcca caacacgacc aatcagactt tcacctacag ggacttccat gattttccct
    19201 gtacggcgga ttgtatcgcc ttcacggata tctgtaaagt cacctaggat gataatacca
    19261 acgtctgttg actccaagtt ttgagccata ccataagagc cgttttcaaa attcaacaac
    19321 tctccactca tgacattttc aaggccatga gcacgcgcga taccgtcccc gatataggtt
    19381 acaacacctg tttcagtcac atcaaaattg ggtttgaaat tttcaatttg ttgcttaatt
    19441 aaagcgctga tttcttgtgc gttaattgcc aaaagaacac cactttctat ttcaaatttt
    19501 ctttaacaac tttaagttgt tgtttaatac tcacatcaat tgtcttgtga ttggcaaaaa
    19561 tgacaaaacc accaatgaga ctttcatcga tttgttcttt tacactcctt actttcagag
    19621 acattttttt ctcaatcaaa gggagcaaac gagtcttctg ttcatcagtt agaggatgag
    19681 cagacgtaat cgtcacttca aatcgatttg tttctttttc aagtcggttc aagcaatcta
    19741 caagcacatc ataaaaaaga tttgctctgt gattgtaggc cagaacctgg ataaagtttt
    19801 gtaataaagg tgacacagaa tcttggaaaa aagcaattgt tttttcctta tccgactcgt
    19861 ctactgccac ttgttttaaa aaagaaggca gacctgtttt ttcaacaact tgcttgattt
    19921 gagtcaagtc tgaaaagata cggtcttctt ctcctttttc aagtaccaat tggacaaaag
    19981 gcatgctgta tttttcaatt acctttactg ttttcttgtc cattaagctt ctcctagctg
    20041 atcgatatac tgatcaatga gtgctttatg ggcatgactg tcaaggtttt gtgagatgat
    20101 tttaccagct aagctgatgg tcaaatctgc gacctcaccc ttaacactct gtaaagcttc
    20161 tactttattt tgagcaattt cttgattggc tttttctttt aagtgtcctg cttctagttt
    20221 agcatctgct aagatattag ccttactttg ctcagctgtt tcctttgcat tttcaatgat
    20281 tgtcttagct tctttacggc taccagccaa ttcatcttcg cgtttttgag ccaatacttc
    20341 tgctttttga cgggcttctt cagctctgtc aatatctgaa gcaatttttt cagctctttc
    20401 ttcgaaaatg cctgtaatat tagaccatgc aaatttttta atcaagacta gcaaaagaat
    20461 aaaagagcca gtgattaaaa taaaattacc aattaattca cctactgtta cgtgcatcag
    20521 ttactccttt ctattcctct tcaatattaa tcttattccc taaatacaca gatgtcaaaa
    20581 gagtaaaaac ataagcttgg atgcaggaaa taaagacaga aaatgcagtc caagccaaat
    20641 tagctccaaa ggctactgga taccaataaa tagcttggtg ggaaagaaga agtaacaaac
    20701 tcgtcatgac ctctcctgca aagatattcc caaaaatccg caaagccaaa gataagaagt
    20761 ttgtaaattc ttccaagata ttcatcggta tgacaaaaac aggactcata aaagatttta
    20821 tacttttttt aaatccacga cgacgaacgc tttctatatg tgtcaacaaa atgacaagaa
    20881 aagataaggt taagtcatac tgtaaattag cggttggcga actccaccag ttagtcccat
    20941 cgatcgtttg aagctttgtc attaagccaa ggttattggc aatcaccatg aaaaggaata
    21001 aacaaaggaa aaagagtgag taatctttca tgtagcgcga accaatgtta ggttctgtaa
    21061 atccaataac aaagtcatag acatactcaa gtacattttg ctttcctttg ggtttcaagg
    21121 tcatattgcg gcttgcccaa taaataaaga caaaaataac tcccacaatc aacaaagtca
    21181 tggctaacat agtcagattg aagataacag gaccaataga gatgattgga ttaatacttt
    21241 cttccatcta aaatcctccc ttttcttctc gttccatgta tttatttgat aataaatgag
    21301 aagacaagag ttacaaagaa agttccttca ataaaggcaa cacctaaaaa catcaaacta
    21361 cgaaactcag aaagcatatc tggttggcgt gctactgatt taaacagtcc attcatcaat
    21421 aaaccttcac cgacagatac gcccatacag gcaatacata agcctaaaaa tgttaaattc
    21481 ataacaaatt ctcctttaaa ataaaattta cttacttagt gtagtcctaa aatttaaatt
    21541 tgtcaacttt taaccgctat tggaagcgtt taataaaaat tatttccatt t
//
LOCUS       DAVHSY010000031        20863 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.032, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000031 DAVHSY010000000
VERSION     DAVHSY010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.032"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            84..542
                     /locus_tag="VVR43_001477"
     CDS             84..542
                     /locus_tag="VVR43_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU6149827.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            555..1163
                     /locus_tag="VVR43_001478"
     CDS             555..1163
                     /locus_tag="VVR43_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149828.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            1234..1566
                     /locus_tag="VVR43_001479"
     CDS             1234..1566
                     /locus_tag="VVR43_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149829.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQSRLISLNKSEF
                     MQLNPGTY"
     gene            1577..2992
                     /gene="ply"
                     /locus_tag="VVR43_001480"
     CDS             1577..2992
                     /gene="ply"
                     /locus_tag="VVR43_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU6149830.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            3873..4589
                     /locus_tag="VVR43_001481"
     CDS             3873..4589
                     /locus_tag="VVR43_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6149831.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            4713..5162
                     /locus_tag="VVR43_001482"
     CDS             4713..5162
                     /locus_tag="VVR43_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU6149832.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            5201..6022
                     /locus_tag="VVR43_001483"
     CDS             5201..6022
                     /locus_tag="VVR43_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149833.1"
                     /translation="MILLAILFTCFLVYLELEVPTYISKITDLLGSQETNLDELWQPA
                     SMMMGMSFLAFLSVVAVGFFASRVAASYISRLRSDIFNRVLDYSQTEIKKFSIPSLLT
                     RTTNDITQVQMLITMGLQVVTRGPIMAIWAIGKILGHSEYWLWAVLVVVIVNVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIIFMSYAM"
     gene            6029..7060
                     /locus_tag="VVR43_001484"
     CDS             6029..7060
                     /locus_tag="VVR43_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6149834.1"
                     /translation="MGFLLMGALFIVFPRTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSVTAHAGQRVAIVGPTGAGKTTIVNLLMKFYEIDKRSIRI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIACALLKDASLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSIIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            7126..7488
                     /locus_tag="VVR43_001485"
     CDS             7126..7488
                     /locus_tag="VVR43_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HEU6149835.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFLQAPYYVPERIAITGKICGVHIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            7485..7988
                     /locus_tag="VVR43_001486"
     CDS             7485..7988
                     /locus_tag="VVR43_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU6149836.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            8102..8548
                     /locus_tag="VVR43_001487"
     CDS             8102..8548
                     /locus_tag="VVR43_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6149837.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            8553..9227
                     /locus_tag="VVR43_001488"
     CDS             8553..9227
                     /locus_tag="VVR43_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149838.1"
                     /translation="MKKKAFGIVFLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWCVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            9479..9667
                     /locus_tag="VVR43_001489"
                     /pseudo
     CDS             9479..9667
                     /locus_tag="VVR43_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647592.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
     gene            9917..10216
                     /locus_tag="VVR43_001490"
     CDS             9917..10216
                     /locus_tag="VVR43_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU6149839.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            10213..10530
                     /locus_tag="VVR43_001491"
     CDS             10213..10530
                     /locus_tag="VVR43_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU6149840.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            10546..11172
                     /locus_tag="VVR43_001492"
     CDS             10546..11172
                     /locus_tag="VVR43_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU6149841.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            11205..11966
                     /locus_tag="VVR43_001493"
     CDS             11205..11966
                     /locus_tag="VVR43_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU6149842.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIETLQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            12044..12439
                     /locus_tag="VVR43_001494"
     CDS             12044..12439
                     /locus_tag="VVR43_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU6149843.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            12595..12879
                     /gene="groES"
                     /locus_tag="VVR43_001495"
     CDS             12595..12879
                     /gene="groES"
                     /locus_tag="VVR43_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU6149844.1"
                     /translation="MLKPLGDRVVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            12895..14517
                     /gene="groL"
                     /locus_tag="VVR43_001496"
     CDS             12895..14517
                     /gene="groL"
                     /locus_tag="VVR43_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU6149845.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            14655..15410
                     /locus_tag="VVR43_001497"
                     /pseudo
     CDS             14655..15410
                     /locus_tag="VVR43_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            15858..16631
                     /locus_tag="VVR43_001498"
     CDS             15858..16631
                     /locus_tag="VVR43_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6149846.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGIGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            16644..16976
                     /locus_tag="VVR43_001499"
     CDS             16644..16976
                     /locus_tag="VVR43_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6149847.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADSISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEHYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKNS"
     gene            17014..17499
                     /locus_tag="VVR43_001500"
                     /pseudo
     CDS             17014..17499
                     /locus_tag="VVR43_001500"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(17854..18387)
                     /locus_tag="VVR43_001501"
     CDS             complement(17854..18387)
                     /locus_tag="VVR43_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU6149848.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(18476..19252)
                     /gene="recX"
                     /locus_tag="VVR43_001502"
     CDS             complement(18476..19252)
                     /gene="recX"
                     /locus_tag="VVR43_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU6149849.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            19290..20645
                     /gene="rlmD"
                     /locus_tag="VVR43_001503"
     CDS             19290..20645
                     /gene="rlmD"
                     /locus_tag="VVR43_001503"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU6149850.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIIDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            20707..20778
                     /locus_tag="VVR43_001504"
     tRNA            20707..20778
                     /locus_tag="VVR43_001504"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20740..20742,aa:Glu,seq:ttc)
BASE COUNT         6477 a         3605 c         4544 g         6237 t
ORIGIN      
        1 agttatagtc cagtttttac tatactttga tattcaaata tgttatacta tggttatcaa
       61 agtaaatgaa aggagttacg aatatgacgc cagaagaaat gtacctgaca gagcgattag
      121 acgtacagat agctcatttt ttaaagaaaa gcgttcaaca tcgtaggcgc tataaggtat
      181 taaaaataac agaaatcgtg gcaggtttcc tcatagctgt cttttgtgct attcctatgc
      241 caggtgatcg ctaccgtttg atttcggttg ccttatccag tctcggcttg ctgtgtgagg
      301 ggattatcaa tttgtataat gcaaaggaaa attggatttc ttaccaaaaa actgcgcaac
      361 tcctggagaa agaaaaattc ctctatcaat gccaaacgga gaaatatgca ggaaagacca
      421 aggcttttgc cctatttgtc aagacatgcg aaggtcttat ctcagaggag attaaccagt
      481 gggaaagtat ccagtcaaaa gaagtggcag ctagtgcaga tgctccagtt aaaaaagagt
      541 aggaggtaga ggaaatgtct caatccagct acctgtcgcc cttgctctgg ttaaaaaaag
      601 aagccgataa ggaaaagatg agcgcgaccc agtgccagat atttttcttt tactatcaaa
      661 tgtttgagct cttatttgct agagaaagcg acatgaaaga cttatgtctg ggaacgaaag
      721 gtttttattt ctcgcagtta gagaaaaatt tgctttctgg agtttcccga tttctaaaaa
      781 acttggaggg gaaagtaact ctcaaggcta accaagaagt atcagctcgc aaagcccttt
      841 ttctagcctt gacaactagc caatcagatt ggcaggagtt agctcctgtt tttgattttt
      901 atcagactat cgggaggctt gaaaatcctt ctctcttgag ttctcaggac agacaacatc
      961 tgatgtggat ttaccagtca gctttggaga aggattatat tgtcaaggtt attggtgaca
     1021 agcattttgt attgaagaga caagatgcta ctaaattgac agcgcgccaa actcaaactt
     1081 tggaaattct gagtcaatca gaagacttgg tcaatcctgt ctatgttaca ttaggagaaa
     1141 agggggtgct cttgcttgat taagagagga gatgttgtag ttctttattt gccttttccg
     1201 actattagta gcgatttggc tgtgaagaat catatgtata tctgtattga caacagcatg
     1261 actaaaaaca aagagttggt taaaaatcag accttcaaac cagctctctt gaccagacgt
     1321 ttggtcaaga actttatgat agaagagccg gatctagctc gtaatccttt tacaagacca
     1381 accttgattg acttagataa ggtatttatg ttggataata cggttattcc gacttcttat
     1441 ctagccagac ggcgacgcaa tgtctcagaa gaattgtacg aggaaatttt ggatcactta
     1501 gtccaatcac ggctgatttc gctgaacaag tctgagttta tgcaactcaa tccaggaact
     1561 tattaggagg tagaagatgg caaataaagc agtaaatgac tttatactag ctatgaatta
     1621 cgataaaaag aaactcttga cccatcaggg agaaagtatt gaaaatcgtt tcatcaaaga
     1681 gggtaatcag ctacccgatg agtttgttgt tatcgaaaga aagaagcgga gcttgtcgac
     1741 aaatacaagt gatatttctg taacagctac caacgacagt cgcctctatc ctggagcact
     1801 tctcgtagtg gatgagacct tgttagagaa taatcccact cttcttgcgg tcgatcgtgc
     1861 tccgatgact tatagtattg atttgcctgg tttggcaagt agcgatagct ttctccaagt
     1921 ggaagacccc agcaattcaa gtgttcgcgg agcggtaaac gatttgttgg ctaagtggca
     1981 tcaagattat ggtcaggtca ataatgtccc agctagaatg cagtatgaaa aaatcacggc
     2041 tcacagcatg gaacaactca aggtcaagtt tggttctgac tttgaaaaga cagggaattc
     2101 tcttgatatt gattttaact ctgtccattc aggcgaaaag cagattcaga ttgttaattt
     2161 taagcagatt tattatacag tcagcgtaga cgctgttaaa aatccaggag atgtgtttca
     2221 agatactgta acggtagagg atttaaaaca gagaggaatt tctgcagagc gtcctttggt
     2281 ctatatttcg agtgttgctt atgggcgcca agtctatctc aagttggaaa ccacgagtaa
     2341 gagtgatgaa gtagaggctg cttttgaagc tttgataaaa ggagtcaagg tagctcctca
     2401 gacagagtgg aagcagattt tggacaatac agaagtgaag gcggttattt tagggggcga
     2461 cccaagttcg ggtgcccgag ttgtaacagg caaggtggat atggtagagg acttgattca
     2521 agaaggcagt cgctttacag cagatcatcc aggcttgccg atttcctata caacttcttt
     2581 tttacgtgac aatgtagttg cgacctttca aaatagtaca gactatgttg agactaaggt
     2641 tacagcttac agaaacggag atttactgct ggatcatagt ggtgcctatg ttgcccaata
     2701 ttatattact tggaatgaat tatcctatga tcatcaaggt aaggaagtct tgactcctaa
     2761 ggcttgggac agaaatgggc aggatttaac ggctcacttt accactagta ttcctttaaa
     2821 agggaatgtt cgtaatctct ctgtcaaaat tagagagtgt accgggcttg cctgggaatg
     2881 gtggcgtacg gtttatgaaa aaaccgattt gccactagtg cgtaagcgga cgatttctat
     2941 ttggggaaca actctctatc ctcaggtaga agataaggta gaaaatgact aggagaggag
     3001 aatgcttgcg acaaaaagag gcgatgatct ctctgcagat atctgaaagt ttatctcttg
     3061 cctagcgatt tccattggag tatgctcgtg atgttaaaat gaatctatca aacagaatgt
     3121 gtaaaaaagt aaaaagggta gccaattctt tgatatacag gggattgatt atcctttact
     3181 tgttttagat gattggaaat tcaagaacga cacgtatcgg aaatattttg ctgtttatat
     3241 ctaataccca tttatggaaa aaatgaaatt aaatatgaac aaatcaattg ctagcaatgg
     3301 tttagaagtg ccagtgtact agtctaactt ctccatcttg ggaacacgta aattatactc
     3361 ttcgaaaatc tcttcaaacc atgtcagccc catccgcaac ctcaaaacag tgttttgagc
     3421 aacctgaggc tagctttcta gtttgctctt tgatttttat tgagtattag aggtttgctt
     3481 agaaactctt ctattgattt cttagaatac aatagcgcct ataagaactg ttgaatttca
     3541 aagtatttac ttgaactatg atatgtctgg agtagactgt caacaaaagg tgcagtatga
     3601 ttgtttttgt cgcttatatc tacaaacttc aaacagtaat ttgagctgac tttgtcaaac
     3661 ttggctgaaa ctttctattt gcagataatg gtctagtttg ttttttgaat gtggatgagt
     3721 gtctgttgat aaagatagaa aggcaagacc atcttagcag gtaaagtgct atcctagctt
     3781 gatttgctaa taaaatccat ttcctctagt gaaaatcaaa aaaacttgtg ttataataag
     3841 aaagattaaa atgtgaaaaa aggagattcc taatgggacg taaatgggcc aatatcgtag
     3901 ccaagaaaac ggctaaagat ggagctaact ctaaagtata tgcaaaattt ggtgtagaaa
     3961 tctatgtagc agctaaaaaa ggtgatccag atccagaatc aaactcagct ttgaaattcg
     4021 ttatcgaccg tgctaaacaa gcccaagtgc caaaacacat tatcgataaa gcgattgata
     4081 aagccaaagg aaacacagac gaaaccttta cagaaggacg ttacgaaggt tttgggccaa
     4141 atggctctat gctaattgtg gatactttga cttctaacgt taaccgtaca gcagccaatg
     4201 tccgtgcagc ctttggtaaa aacggcggaa acatgggcgc ttcaggttct gtttcttacc
     4261 tctttgacaa caaaggtgtt attgtatttg gaggtgaaga tgcagacgca gtctttgagc
     4321 aattgctcga agcggatgta gatgtggatg acgtagaagc acaagaaggt acaatcacag
     4381 tttacacagc gccaactgac cttcacaagg ctatcgttgc cctccgtgag tctggtattg
     4441 aagagttcca agtgactgaa ttggaaatga ttcctcagtc agaagtggaa ttgtcaggcg
     4501 aagaccttga aacctttgaa aaactttaca gcgttcttga agacgacgaa gacgtccaaa
     4561 agatttatac gaacgtagat gggttttaat ttaacctata gaacatgatc ctaagtgaga
     4621 aaatcacttg ggattttttt aatcaagaaa atagttctca tagaaattta attattctcc
     4681 agagaactat ttttatttag aagggggaga ttatggataa accgatgtta gtctttaagc
     4741 gttttggtca tcaaattcac ctgatggtgc aaaaggaagc caaacgttgc ggcattgaat
     4801 ttatgggtgg gccgcaaggt caggttgtgc attttttgga taatcgcgag aaaaaccaag
     4861 acttggtctt gattaaagat atcgagcagg aactcaatat taccaagtct gttgctagta
     4921 atctggttaa gcgtatagtg caaaatggtt tggtggaatt ggaggcgagt cctgttgata
     4981 agcgggctaa gtttgttcgt ctgacggaca aagcacgttc tcagatgcaa caggttaagg
     5041 ctttttttga acgcatagac aagcagttga tggaagacat tgatgaagat gaattactga
     5101 tttttgagaa ggttctcggt caactacagg caaaatatca agggaatagg aggagagaat
     5161 aaagaaatta gccaaaagaa ttagtagaaa agaatggggg atgattttac tagccattct
     5221 ctttacttgc tttttggtct atctagagtt ggaagtgccg acctatatct cgaaaattac
     5281 ggatttgcta ggtagtcaag aaactaattt agatgagttg tggcagccgg caagcatgat
     5341 gatgggaatg tcctttcttg ccttcttgtc cgtagttgca gttggatttt ttgcatcccg
     5401 agtggcggct tcttatatta gtaggctgag aagtgatatt tttaaccgag ttttggatta
     5461 ctcgcagaca gagattaaga aattttcaat tcctagcctc ttgacgcgta ctaccaatga
     5521 cattactcaa gttcaaatgt tgattactat gggcttgcaa gtggtaacgc gtggtccaat
     5581 tatggctatc tgggctattg ggaagatttt aggtcattca gaatactggc tctgggccgt
     5641 acttgtggta gtgattgtca acgtcctgat gacgaccgtt ttgatgacgc tagcctttcc
     5701 aaaacagtcc ttgattcagg ggttgacaga taaactgaac agtatcactc gtgagagttt
     5761 aacaggtatt cgtgtcgttc gtgcctacaa tgcagaggat tatcaaaatg aaaaatttgc
     5821 agcagtaaat gatgaattga cccgtttgaa tttgtttgtc aaccgtctta tggctatttt
     5881 gaatcctatc atgatgggga tttcaagtgg tttgagtgta gcgatttact ggattggggc
     5941 ctatgtgatt aacgacgctg ctccgatagc gcgtctgcct ctctttagtg acatgattat
     6001 tttcatgtct tatgccatgt aggttgtcat gggcttcctt ctcatgggag cactcttcat
     6061 cgtttttccc cgaactatgg tctctgctaa gcggattaat caagttttag atttgcattc
     6121 ttctatccaa aaccctgttc aagtgcagct gactgatgaa aacttcaaag gtcaggtcga
     6181 gtttaaggat gtgaccttcc gctatgcggc aaattcggag gcagttattg aacatgttag
     6241 ctttaaagca gaaactggtc aaacagtggc ctttattggg tcaacaggtt ctggtaaatc
     6301 aactctggtc aatctgattc cacgtttcta cgacgtgtca gcaggagaaa ttctggtgga
     6361 cggtgtcaat gttcaagact atgacttctc tgtgacagct catgctggtc aaagggttgc
     6421 cattgttggg ccgactgggg ctggtaagac aaccattgtc aatcttttga tgaaattcta
     6481 tgagattgat aagagaagta ttcgcattga tggtgtggat accaaggcta tgacgcgttc
     6541 agaagtgcat gatgcctttt caatggtctt gcaggatacc tggctctttg aaggaactat
     6601 tcgagacaat ctcatctata atcaaatagg gattagtgat gaacgaatga tggaagctag
     6661 taaggctgtg ggaattcacc actttattat gaccttgcca gatggctatg ataccatctt
     6721 ggatgacacc gtgaccttgt ctgtaggaca aaaacaacta ttgactattg cttgtgccct
     6781 tcttaaggat gcatcgcttt tgattttgga tgaggcgact tcttctgttg acacacggac
     6841 agaggaattg atccaaaaag ccatggaccg tttgatggaa ggacgcacat cctttgtcat
     6901 tgcccaccgc ttgtcaatca tccgaaatgc agacttgatc ttggtcatga aagatggaaa
     6961 tatcatcgag caaggcaact atgaggaact gatggcgcaa ggtggcttct acgctgactt
     7021 gtacaatagt caatttacag aagatgaagc agaagaataa atcaaaaaaa ggcttgacgg
     7081 ccttcttttt cttatttata ctagtacaca tagaaagaga gaagtatgag tcagaaatta
     7141 tacaatatga aatttgctgc tgtctactta gccttgattg caaaagttga gcgaaagggt
     7201 ggaaaggcag agtcagttca ccaagtgacc agttggttga cagggtatga agtgagtgac
     7261 gttcttgctt gtctggatag ggatgttact tacggagatt tttttctaca agcaccatat
     7321 tatgtccctg aacgaattgc aattacaggg aagatttgcg gtgtccatat tgaggaaatt
     7381 gatgatcctc tgatgcagga aatacgtcgt ttggacaagc tagtggattg gcttgccaag
     7441 gggaaaacat ctcaacaagt tctagaaaag tatgagaagc ataaatgaaa aattatcaag
     7501 aatggtatcg aaatatcagc tccagactaa ctagtcgtcc aattctttta ttcctattac
     7561 gcagtttcaa tcgtttgatg acagtcgcca tgcccctggt ctatctgatc ttgctagtca
     7621 ccacttacct gcaactagga cttggtcagc aagttggggt ttatgtgctt attcctgcat
     7681 caggttttgt ggccttgtcc ctgtttcgta agaaaatcaa tcacccgaga ccttatgaaa
     7741 cttgggatat ctgtcccctt cttgataagg atagttcggg acggtcgatg cccagtcgcc
     7801 atgtcttttc tgcaactatc atctccatgg cctgtctgca tgctagtcta cctattggct
     7861 tagtatgctt gatcttttca gctttgctgg ggttggtgag ggttttaggg ggtgttcatt
     7921 atcccaagga tgtcttggtt ggctatgctt gtggtctggt gtggggattc cttttcttcc
     7981 tattctgaca tgtaagttaa gctagtccta caaccactta ctgcttcaaa ttgaccactt
     8041 gcttttttgc ccttgtattc ctaacttagc tttgatatag tagagtcaga aaggagatgt
     8101 gatgaagtta cgaattgaga ttgacggcaa tttagaggag actgaaattg tcatcaagac
     8161 ccccactttg acagatgaaa ttgcagactt gcaacggctc ttgcaagagt caaaggctcc
     8221 gaggttgact ttttacaagg ggacaggtga atattatcta gacctgtcag aaattctctt
     8281 ctttgaaaca gaagggagca agatctacgc tcataaccag aaggaagctt atgaggttcg
     8341 cctcaagctc tatgagttgg agtctatctt gcctcgctat tttaatcgag tttccaagtc
     8401 aacgatcgca aacatccgtc agatttactc agtggacaag tccttttcag gaacgggcac
     8461 catttccttt tatcagacgc acaaggaggt tcatgtctca cggcattacc aatccctcct
     8521 aaaagaaaat ctaagaaaca tgaggtaata agatgaaaaa gaaagcattt ggtattgtgt
     8581 tccttgtact agcagcttta atattagtac aaggaaattt tggaatccct tctctaggag
     8641 ggcacatttg gcccttgatt ggtattgctt tttttgccta ccaatcagtt ggagctttgt
     8701 tgcgtcgcca cttaacttca gcctctttta cagctctagt agccttaatg attgctaacc
     8761 acttttatgg cattttaccg attccaaacc agacactaat ctgggcagga gttctaatcg
     8821 ttctcggagt aaatatgttg actcattcta acagaacttg gaatgggaaa aaatggtggt
     8881 atgatggtga aaaaaacatt cttatagata aggaagttgc ttttgggaca gggactttct
     8941 acaagcaaga ccaagaattg gtagaagacc aagtagaagt tggttttggc aatgcaaaaa
     9001 tctactatga caatgcagag atgttaggtg attttgcaac tttaaatatt gaagtagctt
     9061 ttggtaatgc aactgtctat gttccgcaac actggtgtgt cgatttgaaa gtagaaacat
     9121 cctttggtgc agccaaggcg gacgctcctg tagcgccaac aagcaaaacc ttgattattc
     9181 gtggagacgt ggcctttggg aagttggagc ttgtctacgt taaataaaaa aatcttcact
     9241 taaaccatca aaatagacgt actaagagta ggaaattgat gccttgctct gatttcagtt
     9301 ctatggttgt tagactttaa aaaatgaaat gttgccttta aaagttgtat atttttcgat
     9361 attttggctc ttacgtttga tgtatctatg tcctacagcg tggatgatgt agtgtaaaat
     9421 gctttaaaaa aatgaatgat attggacagt tttttgaacc tttaattgct caggagccat
     9481 gaaagcaagc acttgagttt atgacaaggg agaatggtat tatgtaagtt cttctggagc
     9541 catgctagcg aatgattggg tcaaagataa tggcaagtgg tattatctag cttcatcagg
     9601 taagatgctt cgcaatacct acacacctga tggttactac gttggtaact caggcgcctg
     9661 gcaataagaa taatactctt cgaaaatctc ttcaaaccac gtcagcttca tccacaacct
     9721 caaaacagtg ttttgagctg acttcgtcag ttctatctac aacctcaaag cagtgctttg
     9781 agcagcctgc ggctagcttc ctagtttggt ctttgatttt cattgagtat aagaagccct
     9841 tttccttaaa ggaagaggct ttttacttgc ttttttgctg tttcctcatt tgtcctaaag
     9901 ccttttttgt gttaaaatga atggtatgaa agctaaaaaa atgtggatgg caggtctggc
     9961 tctgcttggt attgggagcc ttgcccttgc tacgaaaaaa gttgcagatg atcataagct
    10021 catgaagact caggaagagt tgacagcgat tgtacgagac catttttccg acatggggga
    10081 aattgcgacc ctttatgttc aagtttacga aagcagtctg gagagcttgg ttggtggcgt
    10141 catttttgag gatggccgtc attatacctt tgtctatgaa aatgaagacc tagtctatga
    10201 ggaggaagtc ttatgataca gccagcaagt ttagaagaat tagcatcttt agtggaaaaa
    10261 gcgggcaaga aggtcttcct ttttgtggca gactggtgtg gcgattgtcg ttatatttat
    10321 cctgccttac cagagattga agagaccaat ccagagttca cctttattcg aatggaccga
    10381 gatcagtata tggatttggc caaactctgg gatgtttacg gaattcctag ccttgttgtt
    10441 ctagaaaagg acaaggaaat cggtcgtttt gtcaatcgcg accgtaaaag taaggagcaa
    10501 attaacgatt ttttagcagg attgaaatag gagaaaaagg aaacaatgat ttttacgtat
    10561 aacaaagaac atgtcggtga tgtccttatg gtcatcgtga aaaatagcgg agatgccaaa
    10621 ctgaatgtgg aacgcaaagg caaggtagcc cgtgttttcc tcaaagaaaa tggggaaaca
    10681 gtagcttgga acatttttga ggtttcgagc ttgtttgaaa ttgcagagcg cggtcaagtc
    10741 tttttatcag atgagcaagt cgctcgtttg aaccaagaat tacaggcgga aggttttaca
    10801 gaagaaattg ttaatgataa ggaacctaag tttgttgttg gtgaaattgt cgagatggta
    10861 gctcatccag acagtgacca cctcaacatc tgccaagttg cagtcgcaag tgacaagata
    10921 gtgcaaatcg ttgcaggagc acctaatgcg cgtgttgggt tgaaaaccat tgtggctctt
    10981 cctggtgcca tgatgccaaa agggaatttc attttcccag gcgaacttcg tggtgaaaag
    11041 agttttggga tgatgtgtag tcctcgtgaa ttgcatttgc caaatgctcc gcaaaaacgt
    11101 ggggtgcttg aattatcaga agaccaagtt gtcggaacac cgttcgaccc agcgaaacac
    11161 tggactgcct aggaacttgt cagcatctga tagaaggaaa taagatggca aaaaatgtag
    11221 tgattacggg agcaacctca ggaatcggtg aagcgattgc gcgtgcttat ctggagcagg
    11281 gtgaggatgt cgttctaaca ggacgacgga tagacagatt agaaatcctc aagtcggagt
    11341 ttgcagtaag ctttccaaat caaaccgtct ggacttttcc actagatgtg acggatatgg
    11401 tcatggtgaa gactgtttgc tctgatattc tagaaacgat agggaggatt gatatcttgg
    11461 tcaacaacgc cggactggct cttgacttgg ctccctatca agactatgag gagttggata
    11521 tgttgaccat gttggatacc aatgttaaag gtctgatggc ggttactcgc tgtttcttgc
    11581 cagcaatgat aaaagtcaat caaggtcata ttatcaatat ggggtcaacc gcaggaatct
    11641 acgcctatgc tggtgccgct gtttactcag ctaccaaggc agcggttaag accttttcgg
    11701 atggactgcg aattgatacc atcgcaacgg atatcaaggt gacgaccatt cagcctggaa
    11761 ttgtcgaaac agatttttct acagtgcgtt ttcatggtga taaagaacga gctgcgtccg
    11821 tttaccaagg aatagaaact ttgcaagctc aggatattgc agatacagta gtctatgtga
    11881 ctagtcaacc tcgtcgtgtt cagattacag atatgaccat tatggccaat caacaggcga
    11941 caggtttcat ggttcataaa aaataaaaaa ttttctcgaa aagttacaaa tttctgtaac
    12001 tttttttgat ttcctacgaa tagataagta ggaggaagaa aatatgtata ataaagttat
    12061 cttgattgga cgtttaacgt ctacaccaga attgcacaaa accaacaatg acaagtcagt
    12121 agcgcgagca actatcgctg tcaaccgtcg ttacaaagac caaaacggtg aacgtgaagc
    12181 tgattttgtc aatatggttc tatggggcag actagcagaa actttggcaa gctacgcaac
    12241 caaaggtagt ctcatttccg ttgatggaga attgcgtacc cgtcgctttg agaaaaatgg
    12301 tcagatgaat tatgtaaccg aagtccttgt gacaggattc caactcttgg aaagtcgtgc
    12361 ccaacgtgct atgcgtgaaa ataatgcagg ccaagatttg gcagatttgg tcttggaaga
    12421 ggaagaattg ccattttaag aattaaaaag tctgagttgg tctcaggctt tttatcttga
    12481 gaaagtcaga cttttttctt gattatttct gactaagtga tacaatagaa ctatgaatta
    12541 gcactcaggt ataaagagtg ctaataatat ctatctcatt atggaggaaa tcagatgttg
    12601 aaaccattag gggaccgtgt ggtcttaaaa gtagaagaaa aagaacaaac tgttggaggc
    12661 tttgttctcg caggttcagc ccaagaaaaa accaaaacag cccaagttgt ggctactgga
    12721 caaggtgttc gtaccttgaa cggtgacttg gttgctccaa gtgttaaaac tggagatcgt
    12781 gtcttagttg aagcccacgc aggtcttgat gtcaaagatg gcgatgaaaa gtacatcatc
    12841 gtaggcgaag ctaacatttt ggcaatcatt gaggaataga aggagaaagt aagtatgtca
    12901 aaagaaatta aattttcatc agatgcccgt tcagccatgg ttcgtggtgt cgatatcctt
    12961 gcagacactg ttaaagtaac cttgggacca aaaggtcgca atgtcgttct tgaaaagtca
    13021 ttcggttcac ccttgattac caatgacggt gtgaccattg ccaaagaaat cgaattggaa
    13081 gaccattttg aaaatatggg tgctaagtta gtatcagaag tagcttctaa aaccaatgat
    13141 atcgcaggtg acggaactac gactgcaaca gtcttgaccc aagctatcgt ccgtgaagga
    13201 atcaaaaacg tcacagcagg tgcaaatcca atcggtattc gtcgtgggat tgaaacagca
    13261 gttgccgcag cagttgaagc tttgaaaaac aacgccatcc ctgttgccaa taaagaagct
    13321 atcgctcaag ttgcagccgt atcttctcgt tctgaaaaag ttggtgagta catctctgaa
    13381 gcaatggaaa aagttggcaa agacggtgtc atcaccatcg aagagtcacg tggtatggaa
    13441 acagagcttg aagtcgtaga aggaatgcag tttgaccgtg gttacctttc acagtacatg
    13501 gtgacagata gcgaaaaaat ggtggctgac cttgaaaatc cgtacatttt gattacagac
    13561 aagaaaattt ccaatatcca agaaatcttg ccacttttgg aaagcattct ccaaagcaat
    13621 cgtccactct tgattattgc ggatgatgtg gatggtgagg ctcttccaac tcttgttttg
    13681 aacaagattc gtggaacctt caacgtagta gcagtcaagg cacctggttt tggtgaccgt
    13741 cgcaaagcca tgcttgaaga tatcgccatc ttaacaggcg gaacagttat cacagaagac
    13801 cttggtcttg agttgaaaga tgcgacaatt gaagctcttg gtcaagcagc gagagtgacc
    13861 gtggacaaag atagcacggt tattgtagaa ggtgcaggaa atcctgaagc gatttctcac
    13921 cgtgttgcgg ttatcaagtc tcaaatcgaa actacaactt ctgaatttga ccgtgaaaaa
    13981 ttgcaagaac gcttggccaa attgtcaggt ggtgtagcgg ttattaaggt cggagccgca
    14041 actgaaactg agttgaaaga aatgaaactc cgcattgaag atgccctcaa cgctactcgt
    14101 gcagctgttg aagaaggtat tgttgcaggt ggtggaacag ctcttgccaa tgtgattcca
    14161 gctgttgcta ccttggaatt gacaggagat gaagcaacag gacgtaatat tgttctccgt
    14221 gctttggaag aacccgttcg tcaaattgct cacaatgcag gatttgaagg atctatcgtt
    14281 atcgatcgtt tgaaaaatgc tgagcttggt ataggattta acgcagcaac tggcgagtgg
    14341 gttaacatga ttgatcaagg tatcattgat ccagttaaag tgagtcgttc agccctacaa
    14401 aatgcagcat ctgtagccag cttgattttg acaacagaag cagtcgtagc caataaacca
    14461 gaaccagtag ccccagctcc agcaatggat ccaagcatga tgggcgggat gatgtaagca
    14521 ttctatagaa aacaacttat aaaaaacaca aaaggaggga atgactaacc cttcttttta
    14581 taatattcac ttctaaattg atttgagctc tcctaactta tatgataaaa taagactaga
    14641 aaaaggagaa gaacctgatc gatgtagaag aaattctgtg caagatgccc cccaatcaga
    14701 agattaatta tgaccgtgtc atgcagaaaa tggtagaagt atggtagaaa aatgagcaac
    14761 ggccaaccat tctcgtgcat gtttgctgtg ccccttgtag tacctataca ctagaatatt
    14821 tgaccaagta tgcagatgtg accatctatt ttgccaattc taatatccat cccaaggtag
    14881 aataccataa gcgggtctat gtcaccaaga aatttgttag tgattttaat gagcggacag
    14941 gaaatacggt tcagtaccta gaagctccct acgaacccaa ttaataccga aaactagtta
    15001 ggggactaga ggaggagccc gaaggtggcg accgttgcaa ggtttgtttt gactaccgac
    15061 tggataaaac agcgcaagtg gctatggact tgggctttga ctactttggt tcagccttga
    15121 ccatcagtcc tcataagaat tctcaaacca tcaacagcat cggaatcgat gtgcaaaaaa
    15181 tttacacgac ccactatctt cccaacgatt tcaagaaaaa tcaaggctac aaacgttcag
    15241 tagagatgtg tgaggagtat gatatctatc gtcaatgtta ttgtggctgc gtctatgcag
    15301 cccaagccca gaatattgac ctggttcaag ttaagaagga cgctacagca ttcttgttgg
    15361 gtaaggatgt tgagaaagac tattctcata tcaaatttat agtagattga aactagaata
    15421 gtacaccttt acttctaaaa cattgttaga aatcgatttg actgtcctta tttcatttta
    15481 ctatactatt acgaaattag atatataaat gaaaacttgc ctcaaggtag gtttttttgc
    15541 tagtagaaaa gcgatagaca gaaattgttg gactcttaaa aaaatgaagt tttgctcaaa
    15601 agagcttctt aaattaaaac gagcaattat cagttcaaat ctgtttcaaa agaagaacgg
    15661 ataaattaat cgatgctttg tttttgagtt aggaagttaa gcatgccaaa ctgagtcgta
    15721 ggaataaatc tctttctagt aatgtgttgt aactctgcta taatggattt attccttttt
    15781 tgcatttata caacttattt aacactatct ttattcttgt gatataatgc caaattatag
    15841 agtggaggtc atttaaaatg attgataaag taattgaaca atataaaagt catgataatc
    15901 ttgatattcg agtagaattg cataagaagt attcaaaaaa taaattggga tttaataatt
    15961 ggatattttc taactaccaa atcactgatg aagtaaaggt tctagaattg ggatgtggta
    16021 taggagaatt gtggaaaagt aatagtgatt ctatagataa aatgaagcag ttgattgtta
    16081 cagatttttc taaagatatg gtaaaatcaa cgaagtcagt gattggaaat agaaacaatg
    16141 tcaattatga gataatggat attcaaaaga tttcttttga gaatgaaact tttgatattg
    16201 ttattgctaa tatgcttcta catcatgtga atgatattcc taaagctctc tctgaggtga
    16261 atagggtctt aaaaaccgga ggaatttttt actgtgctac atttggtgaa aatggagttg
    16321 taaattattt ggcaagttta tttaaagatg aggttaatca agatttagaa aatagaacgt
    16381 ttactttaca aaatggtaaa aggtacctga gtaggtattt taactctgtc gatacattac
    16441 tctatgatga tgagttacag gtaactagta tagatgacct agttaaatac atccaatcgt
    16501 ttaaaggaat ttcagaaata ggttcactag aagaggaaat aatacgtaaa agattggaaa
    16561 gtgagtttaa taatggtatg ttgatcattc ctaaagaata tggtatgttt atcgctcgaa
    16621 aagaaagtta agggaatgaa agtgtgaaaa attacggaga agcttttcga tattttagaa
    16681 aattaaacgg atattcttta gagtatgctg cagctgattc tatatcaaaa tctcaacttt
    16741 ctagatttga aaggggagaa aatgaaattt ctctttcaac attttttgaa ttattatcaa
    16801 atatcaatgt ttcgatagag aatttttgta atcacttaga acattataaa agatcggagc
    16861 gtgatgattt tttggttaat ttatctccaa atttttatag tttgaatatt aaaggattgg
    16921 aggtaataaa aaataagcaa caaaaacttt ttgagaagag tgggaaaaac tcataaaata
    16981 aatacaatta tggttcaggg attatgaaat cagctagatt gtaatcatgt agttagtaga
    17041 gatgatctaa atttagtata tgactattta ttccagaagg aacgatggga gtcctatgag
    17101 ataacgctga ttggtaattt atatcatctt tttgaaatag attatattta catggtcgga
    17161 aaagaaatac tagagcgtac acattattac gaaaaaatcg gcaagaatag aaatttagtt
    17221 gtgtcagctt gtttaaattt ttggttctgt tgccttgaaa attcacatct aatatatgca
    17281 gactactttg aaatgaaatt acaaaaatta ttaaaagatg acacaaaagt ttttgaaaaa
    17341 tctacattca aatttgtaga aggatataaa atatacctga cagaatctaa agaatctgga
    17401 attaaacaaa tggacaatgt cataaaatat tttgagttta ttgaatctaa aagtattgct
    17461 ttatattttc aaaaacgatt aaatgagctg atagattaaa tagcattttc tctgttgaga
    17521 tattgttttt aaaatattgt actaaatgat tgatgctatg tggaaataca aaaaaatgtt
    17581 tttgatacga agttgacctg tattttttat actaatcatt ttcgtatttt ttgtattaaa
    17641 cgatataagt ttgttgtaaa cttacaagga ataaagacat taaaaaataa cagtatatct
    17701 atttgtttta tatattttac gaattctgca taaatctctt tctagtaatg tgttgtaact
    17761 ctgctataat ggatttattc ctttttgtgt ttacacaatt tattttatac taccaaaaaa
    17821 aggtcaggat tttgttcctg acctttgaca actttaccga ttctttagtt ctacatagcg
    17881 cttgtaccaa atgtttacat aggcttctga gaaaggacca cgtccattgt taatccaatc
    17941 aacaagaatt ttgacatgtt cttttaaaat atagtccaag tcatcagaat aattcatttt
    18001 gcgtttgtga cgctcgtact cttcaacgtc caagagacgt ttttccccat ctgtaaaaat
    18061 tttaacatcc aaatcgtaat caatatactt cagtgcttct tcatccagat agtaggggct
    18121 agccatattg caatagtaag aagttccatt atcacgaatc atggcaatga tattaaacca
    18181 atatttcttg tgaaagtaaa caatagccgg ttctcgagtg acccaacgac gaccatcact
    18241 ttcggtaaca agtgtatgat cgttgacacc aataatggcg ttttctgttg tttttagtac
    18301 catggtgtcc cgccaagttc ggtggagact cccatcatgc ttataacttt gaattgtaat
    18361 aaagtcgcct tcttttggaa gcttcataac taaccaactt tctacaattt ataagtttat
    18421 catttactat tgtaccataa aattacctaa aatctgtgaa tttcacttgg aaatattaaa
    18481 gatattctct aagagcgctt gctatatccg aaaaatcgta gccctttcgt gctaaaactt
    18541 gagttaaacg ctgcttcagt tcgtatcctt catactttcg agcatactta gtatattgct
    18601 tatcaagttc cttgaagatg agttcttgag tcgtttcttg gtcaacttgg ctatctaagt
    18661 cgtcaaaggc aattttagca tcagaataag agaagccctt gttagtcaag ttctggataa
    18721 tcttatcttg caaggcacga gctggaagtt ttccctcata ttttttcaat agtttattag
    18781 ctacacgttg agcaacttca gaaaaatcaa attctttcaa gttctcttct atagtagatt
    18841 ttgaaatccc tttttgagct agtttctgag tcagcacata aggacccttg tctcctgaaa
    18901 gttgattggt attgatgata gcataagcgt actgaccatc attaatccac ttatcttctt
    18961 taagattagc aataacttga gaaacgatgt ttttatcaat atcgtatttt ttcagatatt
    19021 ctctgacttc tttttcagtg cgtgctttaa aggataagtg gtagagggcc agattcttac
    19081 cataagaaaa ttgagcaaag tcttgaatct ctttcaattc ctcttcgctt atcaccttat
    19141 ctctcgataa cataaaacga acaattgtat cttcggtgat atagcatttg tcgccattat
    19201 caagctccat cagatagagt ctttttttct tttcaagttt tgtgattttc atagctctat
    19261 tataactcaa aatgtgataa gataggggta tgaatctgaa agtgaaacaa aaaataccat
    19321 taaaaatcaa gcgcatggga attaacggtg agggaatcgg cttttaccaa aaaacattag
    19381 tctttgtacc aggagctctc aaaggcgaag atatctattg tcagattact tctattagac
    19441 gcaactttgt tgaagcaaaa ttactgaagg tcaacaagaa gtctaaattt cgaattgtgc
    19501 catcttgtac tatttataat gaatgcggag gctgccaaat catgcacctg cattatgata
    19561 agcagctgga gttcaagacg gacttacttc atcaagcgct gaaaaaattt gctcctgcag
    19621 gatatgaaaa ttatgaaatt cgtccaacta ttggaatgca ggaaccaaaa tattacagag
    19681 ctaagttaca atttcagact cgaaaattta aaaatcaggt caaggcgggc ttatatgcac
    19741 aaaactctca ctatttagta gagttgaaag actgcctggt acaagataag gaaacccaag
    19801 tgattgctaa tcgcttagca gaattactta cttatcacca gattccaatc acggatgaga
    19861 gaaaagttct aggtgtccgt actattatgg tccgacgcgc gagaaagacc ggacaggttc
    19921 agattattat tgttacaaac cgccagctta atttaactca attggtaaaa gagttggtta
    19981 aagatttccc agaagttgtg acagtagctg ttaatacaaa tacagctaaa accagtgaga
    20041 tatatggtga aaagacagag attatctggg ggcaagagag tattcaagaa ggtgtactca
    20101 attatgaatt ttcactatcc cctcgagctt tttatcaact aaatcctgag caaacagaag
    20161 tcctctatag cgaagcagta aaagcgctgg atgttgataa agaagaccat ttgattgacg
    20221 cttattgtgg agttggaacg attggatttg cctttgcaaa gaaagtaaaa acactcagag
    20281 gtatggatat tattccagaa gctattgaag atgccaagcg aaatgctaaa agaatgggat
    20341 ttgacaatac tcattatgaa gctggaacgg cagaagagat tattcctcgt tggtacaagg
    20401 aaggctaccg agcagatgct ttgattattg acccaccacg tacaggtctg gatgataagt
    20461 tattagatac tattcttact tatgtaccag aaaaaatggt ttatatttct tgtaatgttt
    20521 cgaccttggc tcgtgatttg gtacgcttag tagaagtcta tgatcttcat tatatccagt
    20581 cggtcgatat gttcccacat acagctcgaa ctgaagctgt tgtaaaatta ataaaaaaag
    20641 tttaaaaaag gtgttgacaa agtttgaaaa gactgtataa tagtaagagt tgaaaataac
    20701 aactcaggtc cgttggtcaa ggggttaaga caccgccttt tcacggcggt aacacgggtt
    20761 cgaatcccgt acggactatg gtatgttgcg tcaggaccac ttgatgaaaa aaagtttaaa
    20821 aaaacttaaa aatcttcaaa aaagtgttga caagcgaaag cag
//
LOCUS       DAVHSY010000032        19413 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.033, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000032 DAVHSY010000000
VERSION     DAVHSY010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19413
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.033"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(<1..951)
                     /locus_tag="VVR43_001505"
     CDS             complement(<1..951)
                     /locus_tag="VVR43_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HEU6149851.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNKLECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLKVVELKTILSKHN
                     LPTSGKKAELITRIINNINVDKLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDITMED
                     YCKEKNNISFKATFGDIKWSILNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHS
                     LIYYIESLIITSSGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPCSTAEEINNYLKKY"
     gene            complement(994..1800)
                     /gene="yidA"
                     /locus_tag="VVR43_001506"
     CDS             complement(994..1800)
                     /gene="yidA"
                     /locus_tag="VVR43_001506"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU6149852.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKSNDESGVAHAIRTWVL"
     gene            complement(1813..3117)
                     /locus_tag="VVR43_001507"
     CDS             complement(1813..3117)
                     /locus_tag="VVR43_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU6149853.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMIAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQSPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPKDKDFFARTSPHLLPFFEKNVTLSD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLYLIENDHFTPNKN"
     gene            3189..3566
                     /locus_tag="VVR43_001508"
     CDS             3189..3566
                     /locus_tag="VVR43_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU6149854.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKNSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            3657..3989
                     /locus_tag="VVR43_001509"
     CDS             3657..3989
                     /locus_tag="VVR43_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU6149855.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            4001..5572
                     /gene="ffh"
                     /locus_tag="VVR43_001510"
     CDS             4001..5572
                     /gene="ffh"
                     /locus_tag="VVR43_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU6149856.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPNRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPNLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(5767..7050)
                     /locus_tag="VVR43_001511"
     CDS             complement(5767..7050)
                     /locus_tag="VVR43_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU6149857.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(7304..8017)
                     /gene="rsmG"
                     /locus_tag="VVR43_001512"
     CDS             complement(7304..8017)
                     /gene="rsmG"
                     /locus_tag="VVR43_001512"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU6149858.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            8111..8671
                     /locus_tag="VVR43_001513"
     CDS             8111..8671
                     /locus_tag="VVR43_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU6149859.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            8673..9572
                     /gene="htpX"
                     /locus_tag="VVR43_001514"
     CDS             8673..9572
                     /gene="htpX"
                     /locus_tag="VVR43_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU6149860.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRIFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(9616..11142)
                     /locus_tag="VVR43_001515"
     CDS             complement(9616..11142)
                     /locus_tag="VVR43_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6149861.1"
                     /translation="MIKINHLTITQNKDLRDLVSDLSMTIQDGEKVAIIGEEGNGKST
                     LLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKLPEELKKKTLHDYFFLDSIDLDYSIL
                     YRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLDEPSNDLDLETV
                     DWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHLDYESYSEQ
                     RKAKFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLS
                     QEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLSIDDRVLVQKLQ
                     LTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHKKLQLDLSPIAY
                     LSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDLVLRKPNFLLLD
                     EPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSSIYRLTEHGLELVNLEDV
                     "
     gene            11901..12443
                     /locus_tag="VVR43_001516"
     CDS             11901..12443
                     /locus_tag="VVR43_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU6149862.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            12443..13072
                     /gene="nth"
                     /locus_tag="VVR43_001517"
     CDS             12443..13072
                     /gene="nth"
                     /locus_tag="VVR43_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU6149863.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            13283..13804
                     /gene="pyrR"
                     /locus_tag="VVR43_001518"
     CDS             13283..13804
                     /gene="pyrR"
                     /locus_tag="VVR43_001518"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU6149864.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            13823..14746
                     /locus_tag="VVR43_001519"
     CDS             13823..14746
                     /locus_tag="VVR43_001519"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU6149865.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            14796..15875
                     /gene="carA"
                     /locus_tag="VVR43_001520"
     CDS             14796..15875
                     /gene="carA"
                     /locus_tag="VVR43_001520"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU6149866.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            16188..19364
                     /gene="carB"
                     /locus_tag="VVR43_001521"
     CDS             16188..19364
                     /gene="carB"
                     /locus_tag="VVR43_001521"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU6149867.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         5687 a         3696 c         4281 g         5749 t
ORIGIN      
        1 atatttcttt aagtaattgt ttatttcttc agcagtagaa caaggtaaat taactcttaa
       61 atagtcaata tcttctttag ataaaaaatg atttgcattc aaaattgaga agcgaaataa
      121 tgcttcatca aaagcaaaat cataatcgtc atcagataat gattccatta atgtttgaat
      181 atgttttagt gagtagtcag gtatcgaatc gggataatat actggataat cagtggctga
      241 aaaattgttt tctaatcctg aactagtaat tatcaaagat tctatgtaat atattaaaga
      301 atgtttaata ttaccttctt gttccaaatg tcttccttga gcctttcgtg tgttagataa
      361 acatccaaaa tctcctgata cagtattcct atgagcttgt ttatttaaaa tactccattt
      421 tatatcacca aaagttgctt taaaagagat attatttttt tctttacaat aatcttccat
      481 agttatgtct ttatcatagt atgctttgat atagtcacta tgttcgataa taagattttg
      541 tgcttctttt gttagtttaa attcgaacgg aatatctaat ttgtcaacgt tgatattatt
      601 aattattctt gtaattaatt ctgctttttt tccagaagta ggtaaattat gtttagataa
      661 tatagttttt aattctacta ctttaagata tgataaagtc ttatttttag tgaagtatcc
      721 taatttgtat aattgattgt gtgtagattc agggtcaatt tgaagagagt atttaaaata
      781 tcttgggaaa ttataatttc tccctgtttt ttgagtccaa tctatgagta tgagttgccc
      841 aggagtaagg ccgcactcta atttgtttag gtaaaaattg ttacaatcag aatttgtgtc
      901 tctattatga ttattttgtt ttaaattaaa tagtttgcta aaaaaattca ttggatttta
      961 ttgctaatca attcttattg aaaaatgata cttttacagt acccatgtac ggatggcatg
     1021 ggcaacgcca gattcatcat tagatttagt gatgtatttg gcgatttttt tgatttctgg
     1081 atttccattt tccatgacaa cagggttgcc aacgacttcc agcatggcac ggtcattttc
     1141 ttcgtctccg atagccatgg tttcatcttt ggttaatcct agtttttcag ctaagtgagt
     1201 aatagctgaa cccttgtcta cattcttttt aaggagttcg aggtagaaag gagcagattt
     1261 gttgatagag tagtgctcgt aaaattcggc tggtattttt tcaatcgcag catcgagaat
     1321 ttctggttca tcgataaaca tacatttaac aatttctttg ccagccattt cttcaggggt
     1381 acggtagaag ataggcatgc tgacgagggt tgattcgtgt acagtgtatg ttccgatatt
     1441 gcgatttgca gtatagatac cgtccttggt aatggcatgc atgtggacac cgagcttgcg
     1501 actgaggaat tccatatcca gataatcctc ataggtcaag gattcgctga taatctcatg
     1561 gccagtagca gtttcttgga caagggcacc attgaaggtc accacatagt caccttggtc
     1621 tctcaactgc aagtcgtcta gaagtttggc aacacctgcg atggggcggc cagttgcaat
     1681 cacgactttg acaccagctt ctttggcatc ttggatggca gaaaagactt caggagtgat
     1741 ttccttttgg ctgttgacaa gggttccgtc gatatcaacg gcaattagtt taatactcat
     1801 aaatttcctc ttctagtttt tatttggggt aaaatgatcg ttctcaatca agtataaaaa
     1861 ttgctgggta atgctagcaa agatactgtt ttgatctaac atttctttcg gaaaatagaa
     1921 acgattatct ccgtgacgac taccagcaag ggattggacg ataggagaca ggctagagag
     1981 ttcggccagt tctccattct tttgtaaaat ctcaatctgt gtccgtggat tttcagattc
     2041 gggacgatag atatcataag ggaggtcaaa gttcttatga atggcagtat agtagtcggg
     2101 atcaaagcca atgtcctcaa ccaattttct catgctagcg agttggtctt gatcttcttg
     2161 tgaaaaggta atggatttaa agaccttgcg gttgacaaag cgttgcgata aatctgcgag
     2221 aattttgtca ggactggtca tccagagctg gaagtaggta ttcatcacac catcatctag
     2281 agccagatag tcagacaagg tcacattttt ttcaaagaaa ggcaggaggt gtggggaagt
     2341 tcgtgcaaag aagtctttgt ccttagggta gagttcctta gcgcgcttga gaagattctg
     2401 taggagaact tccatagcgc gtgttgctgg gtggaaatag acctgcatat acatctggta
     2461 gcgactgagg acatagtctt cgatggcgtg catgccattg cgctgaaagg cgataccatt
     2521 ttcgatagga cgaatgactc ggaggattcg agtcaggtca aattccccat aggatgctcc
     2581 tgtaaaatag gagtcacgca agagatagtc catgcgatct gcgtcaatct gactagaaat
     2641 gagttgtacg acctgcttgt taggataggt atggtctatg acactggcaa ctttctctgg
     2701 aaaatcgggc gctacttgta gcaagacttg gtgaatctct gtctcaggac tttgaataat
     2761 ctcctgagta atagcttcat ggtctgtatc aaagagatgt tcaaaagtat gggagtaggc
     2821 gccatgccca aggtcatgta ggagagcagc gatcatggtc aagagagact cggcaggatt
     2881 ccattcctca ggatattttt cttcgaaaat ctctgtgatg cgtcgtgcaa tttcatagac
     2941 tcctagacag tgagagaagc gactgtgttc tccaccgtgg aaggtataac tggaagttcc
     3001 cagttgtttg atccggcgca aacgctgaaa ttcttttgta ttaatcaagt catagatgat
     3061 ttgattattg acatggatgt agttgtgaac tgggtcacgg aatacttttt cgttcatatg
     3121 accattatag caaaatcctg ctctttttgg taaaatagta ggacaagaga caagaaagag
     3181 ggcctgatgt gaagattcgg atgcgaaata caattcagtt tgatgagcag ttggaagtga
     3241 ttgaccagct ttatgatgtg gaagtgcatg aaaaaggaga ttatagctac ctgcttttct
     3301 ataatgagga aaaggaaaaa gtagtgatta aatttcatgg tcaagaactt gtgatgagcc
     3361 gattttctaa tcccaagacc attatgcgct ttctaaagaa tagcgatagt ttagcctata
     3421 ttcctacacc tatgggcatg caggagttta tcatccaaac gagccattat caagttgata
     3481 ggcaaaagat tgaactagat tatcaactac aaaatcaaga gggacatcct tttgccagct
     3541 atcaattgga aattacttgg ggctaggctc atgtcttttt caaatttagc tatctatctt
     3601 cttggatcgg cttcctagtg tggtagatta ggctaatttt tggtataata aaagttatgg
     3661 aaatcgaaaa aaccaatcgt atgaatgcgc tctttgaatt ttatgcggcg cttttgacag
     3721 ataagcaaat gaattatatc gagctctact acgctgatga ttacagcctt gctgaaattg
     3781 ccgaggagtt cggtgtcagt cgtcaggctg tctatgacaa tatcaagcga acagaaaaga
     3841 ttctggaaga ttatgagatg aaattgcaca tgtactcgga ctatattgtc cgcagtcaga
     3901 tttttgatca gattttggag cgctatccca aggataactt tctgcaggag cagatagaaa
     3961 ttttaacaag cattgataat agagaataag aggaagaaaa atggcatttg aaagtttaac
     4021 agaacgtttg cagaacgtct ttaaaaatct acgtaaaaaa ggaaaaatct ctgaatctga
     4081 tgtccaagag gcaaccaaag aaattcgctt ggccttgctc gaggccgacg ttgccttgcc
     4141 tgttgtaaag gactttatca agaaagttcg tgagcgtgca gtcgggcatg aggtcattga
     4201 tacacttaat cctgcgcaac agattattaa aatcgttgat gaggaactga cagccgtttt
     4261 aggttctgat acggcagaaa ttatcaagtc acctaagatt ccaaccatca tcatgatggt
     4321 tggtttacaa ggggctggta aaacaacctt tgctggtaaa ttggccaaca aactcaagaa
     4381 agaagaaaat gctcgtcctt tgatgattgc ggcggatatt tatcgtccag ctgccattga
     4441 ccagcttaag accttgggac aacagattga tgtgcctgtc tttgcacttg gaacagaagt
     4501 accagctgtt gagattgtac gtcaaggttt ggagcaagcc caaactaatc ataacgacta
     4561 tgtcttgatt gatactgcgg gtcgtttgca gattgatgag ctcctcatga atgagcttcg
     4621 tgatgtgaaa gcattggctc aaccaaatga aatcttgctt gtcgttgatg ctatgattgg
     4681 tcaggaagca gccaatgttg cgcgtgagtt taatgctcag ttggaagtga ctggggtcat
     4741 ccttaccaag attgatggcg atactcgtgg tggtgcggct ctatcggttc gtcacatcac
     4801 tggaaaacca atcaagttca ctggtacagg tgaaaaaatt acagatatcg aaaccttcca
     4861 cccagaccgt atgtctagcc gtatccttgg catgggggat atgctcactt tgattgagaa
     4921 agcttctcag gaatacgatg aacaaaaagc ccttgaaatg gctgagaaga tgcgcgaaaa
     4981 cacctttgat tttaatgatt tcatcgatca attagatcag gtgcaaaata tggggccgat
     5041 ggaagacttg ctcaagatga ttccaggtat ggccaacaat ccagcacttc aaaacatgaa
     5101 ggtggatgaa cgccagattg ctcgtaaacg tgccattgtg tcttcgatga cacctgaaga
     5161 acgtgaaaac ccagatttgt taaatccaaa ccgtcgccgt cgtattgctg ctggttctgg
     5221 aaatacattc gtcgaagtca ataaattcat caaggacttt aaccaggcta aacagctcat
     5281 gcagggtgtt atgtctgggg atatgaataa aatgatgaag caaatgggga ttaatccaaa
     5341 taaccttcct aaaaatatgc caaatatggg aggaatggat atgtctgccc ttgaaggaat
     5401 gatgggacaa ggcggtatgc ctaacttatc agctctcgga ggagcaggaa tgccagatat
     5461 gagccagatg tttggtggcg gtttgaaagg taaaattggt gaatttgcca tgaaacagtc
     5521 catgaaacgt atggctaaca aaatgaagaa agcgaagaag aaacgcaagt aagacaagag
     5581 attgatgcaa atctcatttg atgagaaaat aaagtaaaaa tttctatgat aaaacgcaca
     5641 gtatcaaggt tttagaatat ctgatattat acgttttttg attttaataa ttttgttaag
     5701 acacttttat tatggtatac gaaaaatcca ctcagctgtc tgagtggatt aggtgtattt
     5761 agactcttag tctttatttt cgtatggcaa gatcaagttc aagatgattc ctgtcatggc
     5821 tgaaagggca gtacctgaaa gtgtaactgg accaagttta aggatagctc ctccaagtcc
     5881 aagaaccaac atagcacttg cgatgatgag gtttcgcatt tgagcgaaat caacacgttc
     5941 tttaatcaag actttcaaac cattgctggc gataacccca tagagaagga ttgacatacc
     6001 accaagtaca gcgtttggaa tagttgaaat caaggcagtg aatttaccaa ggaagctgag
     6061 ggcaatcgcg atgaaggcag cgttacggat aactgagaca gaagcgatac gagtcatacc
     6121 gataacccct gtattttctc cgtaagttgt attggctggt ccaccaagga aggcagaaac
     6181 agaagttgcg ataccgtcac caataagagt acggtgaaga cctggttctt ttaagaattg
     6241 acggccacag atttgaccca aaacagtatg gtctccgata tgttcagaaa ttgttacgat
     6301 agcgattggc aagatagcga tggcttctgg accaaagtaa agattgtact ctttaaaggc
     6361 accacctgtg ctaaatggca agtagaaacc aggaatttca aaccagttag cttctaggac
     6421 aggcgtaaag tcaaccaaac caagagttag tgcgaagagg taaccaccga taatggcaaa
     6481 gaggaatgga atgattcgta ggaagccttt tccttttgta ttgataaagg cagcaattag
     6541 gaaagtaaca acggctacca gagcattttt ccaatttccg tctgctacaa gacctgcatt
     6601 ggtaacagct gaacctgcaa gtccaagacc gataacgatg atcataggac cgataatgat
     6661 tggtggcaag agtttatcaa tccattttgt tcctacaaat cggatgctgg tagcaacaag
     6721 gacatagacc aaaccagtca agataacccc tgtttgggca gcagatacat ccccccccat
     6781 ttctttcata gccagtgaca tagctgtgat aaaggcgaat gaagaaccta gataaactgg
     6841 aactttaaaa ccagtagcaa tcatgtagat gagtgttcca acacctgaag caaaaagggc
     6901 aacagataca ggcattccca aaatcaatgg taccaagatg gtcgcaccaa acatggcgaa
     6961 aacgtgttgg aaactaagga gaattccttt tccagccgaa ggacgttggt caacgtctag
     7021 taacaaatca acagttgatt cttgtttcat ataaacctca cttttgggca tcaaaaaaga
     7081 gcccattatt ttacagcaat aggccctcag agtaagactt ctttaaaatt tagattttaa
     7141 agagttttaa atatttctgc gtcttcgtca cctcacggga tgacattaaa aacctttgct
     7201 taggatagta tagcagaaaa aaatgatttt gtaaatcatt ttttcccgag cctagaaata
     7261 aaagagcgag gctgattttg taaacctttg tttactaaaa aatttaaagt gggcgtttat
     7321 ttggcatacc agccttacgt ggatatttat ttggtgtttc ttttttcttt tctaccactg
     7381 tgatatagcg cggatctcta ttcggtaggg cgtagctgag attgtcttcg accttactaa
     7441 aaaggagatt gagggcattc ttagcttcta ataattcctc aggcgcattg ctagccttga
     7501 gtgctaatag tttgccacca accttaaggt agggaatagt caattcagat aggacctgca
     7561 tacgggcaac cgcacgagct gttacaaaat catattgagc acggaagttc ttgtcttggg
     7621 caaaatcttc ggcacgtccg tggtagaaat gaactccgtt caaatccagt tcttgagcca
     7681 agagttgtag gaagttgatg cgcttattga gtgaatcaat aatggtcaca tctaactccg
     7741 gatagagaat tttcattggt agactcggaa atcctgcccc agccccgata tcaagaagtt
     7801 tgatagtttc attgggaatc aaaccttgaa gaatgggtgc aatcgaatcg taaaaatgtt
     7861 tgagataaac ttcttccttg tccgtaatcg ccgtcaaatt aatcttctca ttccactcga
     7921 ccaagagctc aaaataacgt tcaaattgtt ctttttgctg gtccgaaagt ggaagattct
     7981 gctcggcaag caagttgtaa aatgtttttg gtttcatagt tatttccttc tttagtatca
     8041 tcttatttta ccacaatcat agaaaatttg atatactggt actaatctaa aagcagaaag
     8101 gacttatatt atgacttgga ttattcttgg agttttagct cttgttgtta tttttgtgat
     8161 tgttagctat aacggtttgg ttaaaaatcg tatgcaaacc aaggaggctt ggagtcagat
     8221 tgatgttcag ttgaaacgtc gcaatgatct cttgccaaac ttgattgaga ctgtaaaagg
     8281 ttatgccaaa tatgaaggtt ctacccttga aaaggtggca gaactacgta accaagtggc
     8341 ggcagcgact tcaccagcag aagctatgaa agccagtgat gccctcactc gtcaggtttc
     8401 aggtattttt gcagttgcag aaagctatcc agatttgaaa gctagtgcta actttgttaa
     8461 attgcaagag gagttgacaa acacagaaaa taaaatttct tactctcgtc aactctataa
     8521 cagtgttgtc agcaactaca atgtaaaatt agaaactttc ccgagcaata ttatcgctgg
     8581 aatgtttgga tttaaagcgg cagatttcct tcaaacacct gaagaggaaa agtcggttcc
     8641 taaagttgat tttagcggtt taggtgacta agatgttgtt tgatcaaatt gcaagcaata
     8701 aacgaaaaac ctggattttg ttgctggtat ttttcctact cttagctctt gttggttatg
     8761 cggttggtta tctctttata agatctggac ttggtggttt ggttatcgca ctgattatcg
     8821 gctttatcta cgctttgtct atgatttttc aatcgacaga gattgtcatg tccatgaatg
     8881 gagcgcgtga ggtggatgag caaacggcac cagacctcta ccatgtagtg gaagatatgg
     8941 ctctggtcgc tcagattcct atgccccgta ttttcattat tgatgatcca gccttaaatg
     9001 cctttgcgac aggttctaat cctcaaaatg cggctgttgc tgcgacttca ggtctactag
     9061 ctatcatgaa tcgtgaagaa ctagaagctg ttatgggaca tgaagtcagt catattcgta
     9121 attatgatat ccgtatttcg actattgcag ttgcccttgc tagtgctatc accatgcttt
     9181 ctagtatggc aggtcgtatg atgtggtggg gtggagcagg tcgcagacga agtgatgatg
     9241 accgagatgg aaatggtctt gaaatcatta tgctagtggt ttccctacta gctattgtac
     9301 tggcacctct cgctgcaacc ttggttcagc tcgctatttc tcgtcagagg gaatttctgg
     9361 cagatgcatc tagtgtcgag ctgactcgca atccccaggg aatgattaat gccctagata
     9421 agttggacaa tagcaaacct atgagtcgcc acgtcgatga tgctagcagt gctctttata
     9481 tcaatgatcc caagaaaggt ggggggttcc aaaaactctt ttatacccac ccacctatct
     9541 cagaacggat tgaacgttta aaacagatgt aaaagaatcc agaggtcgtc tctggatttt
     9601 tgctatgttg caaatttata catcttctaa attaactaac tccaaaccgt gttctgtcaa
     9661 gcggtagatg cttgaacaga cctcttttaa gaaacgacgg tcatgcgaaa cagtgatgag
     9721 accgcctgga taggttgcaa agagttttct gatttggggt tgagaagtgg gagaaaagtt
     9781 tcgtgtgggt tcatccagca ggagaaagtt tggtttgcgc aggactaaat ccaaaagcag
     9841 gagttttccc tgttgtccgc cagataagga gcgaatttga tgctgcattt ctggataact
     9901 gaaattgaga ctagctaggt gagattggat tttctgtagt tcctcttttt ccccagtttt
     9961 gctgaggtag gctattggtg ataaatccaa ttgcagtttt ttgtggtaat cttgtggcat
    10021 aaaaccaagg gaaatctctc ttttatcatt cagaagttgc tttaatttgg ctaacagagt
    10081 tgatttccca acaccatttg gcccgataat accgattttt tcttgcccac ggacagttag
    10141 ttgtagtttt tgaaccaaaa ctcggtcgtc aatggacaaa ttttcttttt ccagttggac
    10201 taagacttta gaagctggta atggttggat gtctgaaaag aaaagttgga tttgttcctc
    10261 ttcaagtggc ttttgagtca tggactgagc tgccttttcg tagcgttttt cttgtgagag
    10321 gacagttttc atctttttag ccaataggcg accggcagta ctgtctttgg tagctcgaag
    10381 cgcagtttct acattttgtt tgactctccg atgtttttcc atggttttat cgtaggctct
    10441 ttggttgtta gcagcttgct gactttgttt ggcaaattta gcctttctct gctcactata
    10501 gctttcatag tctaaatgct ctactagcgt ttccgcttct ttacggtgtt tgaccagtcg
    10561 caagtgaaca atagtgtctg ccgtttcaga aagaaagtct tcatcatggg aaatgaaaat
    10621 aacggtttgc ctggtctttt gaatctggcc ttttaaccaa tcaactgtct caaggtctag
    10681 gtcatttgaa ggttcatcta aaaatagaat ctcaaagggt ttggctaact catggataag
    10741 ctgaattttc aaagcttctc cccctgatag attgccaatc tcttggtcac ttgcgaaacg
    10801 attgctatca aaatgcaatt cctccgccaa acgatagagg atactgtagt ctaaatcaat
    10861 agaatctaaa aagaagtagt cgtgtaaagt tttctttttc agctcctcgg gaagtttttg
    10921 aggaatgtag gccagtgact gataatcaga ctggatgtct cccttgatag tgaaatcaga
    10981 caaatcttcc cccattaaag ttttaagtaa ggttgattta ccatttcctt cttcgccaat
    11041 aatagctacc ttttccccgt cttgtatggt catgcttagg tcagagacaa ggtctcgtaa
    11101 atctttgttt tgtgtgatgg tcaggtgatt gatttttatc ataactattg ccctttctag
    11161 aatgttcata gtgcataaca aaaagctcta ctttacctag tagagcccaa agtctatgtc
    11221 aaaaaaactc tattaacatg ccagaaaaag ggcataaaag agcacacaaa aagagacaaa
    11281 aacaagatct actaaataaa ggttctttat ttgatagact tagttgttca tgtctccctt
    11341 acctcctagt attagtatct ttatactata cttttaagga aattttgtca acagaaaact
    11401 ggaaattcta tgctctaaaa tccaaaaaca ggtctataga gacttagtac gtgtttgaca
    11461 tgctcgtaat ggattttatc atagtttcgc caagcagtgc gttcttgatt gtttagtttt
    11521 aggctaccca gtccaatcat aggactggtg ggttggtaaa atttctcaag atcaattaag
    11581 atactgttgt tcaacttttc cgttttttga gttcttgcat agtagtgttt agcagctctt
    11641 gtagtcgaat atcatctgcc gtaccctgtt tacagttttg gtagctttta tttaacttgg
    11701 ataggagttg aatgagtttc ttgtcttccg tgtgagcatc ctccttgatc tgatgtactc
    11761 tttccctata gtatagcact aaaaaataaa accgtcatag tgaatatgtt aaaatttcga
    11821 attttaatta caaagtttgg tgtgctgatt tgtagccttt tcatggtata atcaagagag
    11881 taaatcttta tggaggaagt atgaaattaa atattcaaga aattcgtaag cagtctgaag
    11941 gtttgaactt tgaacaaacg ttagatttag ttgatgacct gcgtgcacgt aatcaagaaa
    12001 ttttagatgt aaaagatatc cttgcagttg ggaaagtaca atatgaagac cgtatgtatt
    12061 tcttagatta tcaactatct tataccattg ttcttgcttc gagtcgcagt atggagccag
    12121 ttgagttagt tgaatcttat ccagtcacgg aagttttcat ggaaggcgca actaaccagc
    12181 tagatcaaga agttttagat gatgacttgg tcttgcccat cgaaaatggg gagcttgacc
    12241 ttgctgagag tgtatcagac aatatcctgc taaacattcc tatcaaggtc ttgacggctg
    12301 aagaagaagc tggtcaagga tttgtctcag gaaatgactg gcaaatcatg acagaggaag
    12361 aataccaagc tcaacaagca gtaaagaaag aagaaaacag tccttttgct ggcttacaag
    12421 gactatttga cggagatgaa taatggtctt gtcaaaaaaa cgagcacgaa aggtgctaga
    12481 agaaatcatt gccctcttcc cagatgccaa gcctagtctt gattttacca atcattttga
    12541 actcctggtt gcggtcatgt tatcagccca gacgacagat gcagcggtaa ataaggccac
    12601 accaggtctc tttgttgcct ttccaacacc ccaagctatg tctgtagcga cagagagtga
    12661 gattgcttca catatttctc gcttgggatt gtatcggaat aaagctaaat tccttaaaaa
    12721 atgtgcccaa cagttactag acgattttga tggtcaagtc cctcagacac gtgaagaatt
    12781 ggagagtttg gcaggtgttg gtcgcaagac agccaatgtt gtcatgagtg taggatttgg
    12841 gattccagcc tttgcagtgg atactcatgt ggagcgtatt tgcaaacacc acgatattgt
    12901 caaaaaatca gcgacgccac ttgaggtgga aaagcgggtc atggatatct tgccgcctga
    12961 gcagtggtta gctgcccatc aggccatgat ttattttgga agagccattt gccatccaaa
    13021 aaatccagag tgtgaccagt acccacaatt atatgatttt agcaatttgt aagatgctac
    13081 attgaaactt tttgcttgat tttaagcatg ctttgtgcta tagtaaatga taactaaata
    13141 ttcctttaaa cctgtcccgt gaggcaggca aggagcgcga taaagtagaa gggtgaagtc
    13201 tatactgtgt gcagtagggc tcgcttggct ataaatttca agtctccttg tttaaggaga
    13261 cttttctttt tggaggtttg tcatgaaaac aaaagaagtt gtagacgaat tgaccgtcaa
    13321 acgagcgatt acgcgtatta cttatgagat tatcgaacgc aacaaagatt tgaataagat
    13381 tgtcttggct ggtattaaaa ctcgtggtgt ctttattgcc caccgaatcc aagaacgttt
    13441 gaagcagtta gaaaatcttt cagttcctgt tgtggaattg gatactaaac ctttccgtga
    13501 tgatgttaaa agtggagaag atacttcttt ggtttctgtc gatgtgacag accgcgaagt
    13561 tatcttggtg gatgatgtgc tctatacagg tcgtaccatc cgtgctgcta ttgataatat
    13621 tgtcggtcat ggtcgtcctg cgcgtgtgag tttagcagtt ctagtcgatc gtggacatag
    13681 agaattgcca atccgtccag attacgttgg aaaaaatatc ccaaccagtc gttctgaaga
    13741 aatcatcgta gagatgacag aacttgatga ccaagacaga gttctgatta ctgaagaagc
    13801 ttagaaagtt aaaggagtag ccatgtcaga aaatcaacaa gcattgaacc atgtggtgtc
    13861 catggaagac ctcactgtcg atcaagtaat gaaattgatc aagcgaggaa ttgagtttaa
    13921 aaatggagcc cagcttccct atgaagacca tccgattgtt tccaatctct tctttgagga
    13981 ttctacacgg acacataagt cctttgaagt cgcagagatt aaacttggat tggaacgact
    14041 tgactttgat gtgaagacta gttcggttaa taagggtgag acactttatg acaccatttt
    14101 gactctgtct gctttaggag tggatgtctg tgtgattcgc catccagagg tcgactacta
    14161 tagagaattg attgctagtc caacgattac gacttccatc atcaatggtg gagatggttc
    14221 gggccaacac cctagccaga gcttgcttga tttgatgacc atttatgagg aatttggcca
    14281 ctttgagggt cttaaagttg ctattgcagg tgacttggac cactcacgcg ttgccaaatc
    14341 caatatgcag attttgaaac gcttgggatc tgaactcttt ttcgctggac ctgaggaatg
    14401 gagaagtcaa gagtttgcag actatggaca gtttgtaacc attgatgaaa tcattgatca
    14461 ggttgatgtc atgatgtttc tccgtgtgca acacgaacgc catgatagtg gagctgtatt
    14521 ttcaaaagaa gactaccatg cccaacatgg cttgactcaa gaacgttacg atcgtttgaa
    14581 agaaacagca atcctcatgc acccagctcc aatcaatcgt gatgtagaaa tagcagacca
    14641 cttggttgaa gcaccaaaat cacggattgt ccaacaaatg accaatggtg tctttgttcg
    14701 aatggcaatc ttagaatccg tactagcgag tagaaacgcc aactaaaaca caagacgtta
    14761 aaagacgcca gtgagcgtcc acgagaggtg aaaatatgac aaaaagaatt ctagtattag
    14821 aagatggcac agtttttgaa ggcaaggcct tcggagcaga tattgatgta acaggcgaaa
    14881 tcgtctttaa tacagggatg accggctacc aagaatccat tacagaccag tcttataatg
    14941 gacaaatctt gacctttact tatcctttgg taggaaatta tggtattaat cgtgatgatt
    15001 atgaatccat tattccaact tgtaagggag tcgttgtttt tgaagaagcg cgtagagcta
    15061 gcaactggcg caaccaaatg accttggatg aatttttgaa agccaagaaa attccaggga
    15121 tttcaggaat tgatacgcgt gctcttacca agattatccg taagcatggt actatgcgtg
    15181 caaccttgac ccatgttggg gacagtatgg accatgtgac ggaccagctc caagcaacag
    15241 ttttaccgac agacaatatc aaacaggttt ctactaaaac gtcttatcca gctccaggag
    15301 ttggtttgag cgtggtgcta gtggactttg gtctcaagca ctcaatccta cgtgaacttt
    15361 ctaaacgcaa ctgtaacgtg acagttgttc cttattcgac aacggctgaa gaaattctcc
    15421 atctcaatcc tgacggagtt atgttgtcaa atggtccagg taacccagaa gacgttccac
    15481 aagcactcga catgattcgc ggtgtacaag gaaaaattcc aatctttggt atttgtatgg
    15541 gacaccaact ctttgcaatg gcaaacgggg ctaagaccta taagatgaag tttggccacc
    15601 gtggattcaa ccatgcggta cgtgaaatcg caacaggacg agtagacttc accagccaga
    15661 accatggtta tgcagtcagc cgcgaggatt tgccagagca cttgattatt acccacgaag
    15721 aaatcaatga caagtcagtg gaaggtgtgc gccacagata ccaacctgct ttctctgttc
    15781 aataccaccc agatgcagct cctgggccac acgacgctag ctacctattt gacgagttta
    15841 tcgagatgat ggaagttttt aaacaatcaa actaagaacg agtaaaagct cgtcggagaa
    15901 tttatgtaac tgaacacgga cggaaagctc agaatgtaga gaaaccaact tggattgtca
    15961 atccttcctt gatttcctaa aattcaatcg ctttctattc gtcctttgta tcttatttaa
    16021 tgtcgccctg agaggcgacg aatagaaagg agaagggtgc tccgtatttg ctgaactgaa
    16081 tacgggctac ggacggtgct aaaaagatag ttattcctag aactgacagt tcttcgtcat
    16141 aactcctatt ttagctttgt ccgcttgaca cccttaatat cttatatatg cctaaacgta
    16201 ctgatattca aaaaattatg gtgattggtt ctggtccgat tattattggt caggctgctg
    16261 agtttgacta cgctgggact caggcttgct tgtcgttgaa agaggaaggt tatgaggttg
    16321 ttttggttaa ctcaaatcct gcaaccatca tgacggacaa ggaaattgct gacaaggttt
    16381 acattgaacc gattacactt gagtttgtga cacgtattct tcgtaaggaa ggtccagatg
    16441 ccttgctacc aacactcggt ggtcagacag gtctcaacat ggccatggaa ttatctaaaa
    16501 atggtatcct agacgagctt ggcgttgaac ttctgggtac caaattatct gccattgacc
    16561 aagcggagga ccgtgacctc tttaaacaat tgatggaaga gcttgaacaa cccattccag
    16621 aatctgaaat tgttaacaca gtagaagaag cagttgcctt tgcagcgaca attggctacc
    16681 cagtcatcgt tcgtccagcc tttacccttg gtggtactgg tggtggtatg tgtgccaacg
    16741 agaaagaatt gcgtgaaatc actgaaaatg gtttgaaatt gtcacctgtt acccaatgtt
    16801 tgattgagcg ttcgattgcc ggtttcaagg aaattgaata cgaagtgatg cgtgactcag
    16861 ctgacaatgc cttggttgtt tgtaacatgg aaaactttga cccagttggg attcacacag
    16921 gggattccat tgtatttgcc cctgcgcaaa ccatgtcaga ctatgaaaac caaatgcttc
    16981 gtgatgcgag cttgagcatt attcgtgccc tcaagattga aggtggatgt aatgttcagc
    17041 tagctcttga tcctaacagc ttcaagtatt atgttatcga agtaaaccct cgtgtatcac
    17101 gttcgtcagc ccttgcttct aaagcgacag gatatccgat tgctaagttg gctgccaaga
    17161 ttgcagtagg tttgaccttg gatgaggtta taaacccagt tacaggttca acctatgcca
    17221 tgtttgaacc agcccttgac tacgtagttg ctaagattcc acgtttccca tttgacaagt
    17281 ttgaaaaggg tgaacgccgt ctcggtacac aaatgaaggc gactggagaa gtcatggcaa
    17341 tcggtcgtaa catcgaggaa tctcttctca aggcctgccg ctcccttgaa attggggtgc
    17401 accacaatga aatacctgaa cttgcagcag tttctgatga tgccttgatt gaaaaggttg
    17461 tcaaagccca agatgaccgt ctcttctacg tatcagaagc cattcgtcgt ggctacacac
    17521 ctgaagaaat tgcagagctt acaaaaattg atatcttcta tcttgataaa ctcttgcata
    17581 tctttgaaat tgagcaagaa ttgggtgctc atccacaaga tctagaagtt ttgaaaacag
    17641 ccaaacttaa tggtttttca gaccgtaaga ttgctgaact ctggggaacg actgatgata
    17701 aagttcgcca acttcgcttg gaaaacaaga ttgttccagt ttataagatg gtagacactt
    17761 gtgcggcaga gttcgactcc gaaacgccat atttctattc aacctatggt tgggaaaatg
    17821 aatctatcag atctgataaa gaatctgtac ttgtcctagg ttcaggtcca atccgtatcg
    17881 gtcaaggggt tgagtttgac tacgcaaccg ttcactctgt taaggctatc caggcagctg
    17941 gttatgaagc tatcatcatg aactcaaacc cagagaccgt ttcaacagac ttctctgtat
    18001 cagataagct ttactttgag ccattgacat tcgaagatgt tatgaacgtc attgacttgg
    18061 aacaaccaaa gggagttatc gttcagttcg gtggtcaaac agccatcaac cttgcggagc
    18121 cattggcaaa agcaggtgtg accatccttg gtacacaggt tgctgaccta gaccgtgccg
    18181 aagaccgtga cctcttcgag caagctctca aagaattgga tattccacag ccaccaggac
    18241 aaacggctac caatgaagaa gaagcagctc ttgcagctcg taagattggc ttcccagttc
    18301 ttgtccgccc atcttatgta cttggtggac gtgccatgga aatcgttgaa aacgaagaag
    18361 accttcgttc ttacatgcga actgctgtta aggctagtcc agaccatcca gttcttgtcg
    18421 actcttatat cgttgggcaa gagtgcgaag ttgatgccat ttcagatggt aaaaatgtac
    18481 tcattcctgg tatcatggag catatcgaac gtgctggtgt ccactcaggt gactcaatgg
    18541 ctgtttaccc accacaaacc ttgtcgcaaa aggttcagga gaccatcgca gactacacca
    18601 aacgcttagc aatcggtctt cactgccttg gaatgatgaa catccagttt gttatcaagg
    18661 atgaaaaagt ctacgttatt gaggtcaatc cacgtgccag ccgtaccgtt ccattcctat
    18721 ctaaggtaac caatattcct atggctcaag tagcgaccaa gctcattctt ggtcaaagtt
    18781 tatcagaact tggctaccaa aatggacttt accctgaaag cacccgtgtt catatcaagg
    18841 cacctgtctt ctcctttacc aaactagcta aggtagacag cttgctcggt cctgaaatga
    18901 agtcaacagg tgaagttatg ggttctgatg ctactttgga aaaagctctc tataaagcct
    18961 ttgaagcttc ttatctacac ttgccaactt ttggtaatgt cgtctttacc atcgctgatg
    19021 atgccaaaga agaagccttg aacttggctc gtcgtttcca aaacattggt tatggaatcc
    19081 ttgcgacaga agggacagca gccttctttg ctagtcatgg cttgcaagcc caacctgttg
    19141 gtaagattgg tgatgacgat aaggatatcc caagttttgt acgcaaagga agaattcaag
    19201 ctatcattaa cacagtagga acaaaacgaa ctgctgacga agatggtgag caaattcgtc
    19261 gttcagccat tgaacacggg gtgcccctct tcacagcgct agatacagct aatgccatgc
    19321 ttaaggtact tgaaagtcgt agctttgtta cagaagcgat ttaaatagaa aaataagata
    19381 tagcagactg aatttagaac agtacacagg aat
//
LOCUS       DAVHSY010000033        19109 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.034, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000033 DAVHSY010000000
VERSION     DAVHSY010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19109
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.034"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            1110..2369
                     /locus_tag="VVR43_001522"
     CDS             1110..2369
                     /locus_tag="VVR43_001522"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU6149868.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            2385..2936
                     /locus_tag="VVR43_001523"
     CDS             2385..2936
                     /locus_tag="VVR43_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6149869.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENKASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            2929..4206
                     /locus_tag="VVR43_001524"
     CDS             2929..4206
                     /locus_tag="VVR43_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU6149870.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            4222..5082
                     /locus_tag="VVR43_001525"
     CDS             4222..5082
                     /locus_tag="VVR43_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU6149871.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            5463..6267
                     /locus_tag="VVR43_001526"
     CDS             join(5463..5831,5833..6267)
                     /locus_tag="VVR43_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU6149872.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMSTLQYVREYRTYEQIAADFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKELANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     SHDMKLFKMSCRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTAEDKACNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            6459..8750
                     /gene="pcrA"
                     /locus_tag="VVR43_001527"
     CDS             6459..8750
                     /gene="pcrA"
                     /locus_tag="VVR43_001527"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU6149873.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            8793..9473
                     /gene="radC"
                     /locus_tag="VVR43_001528"
     CDS             8793..9473
                     /gene="radC"
                     /locus_tag="VVR43_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU6149874.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(9470..10159)
                     /locus_tag="VVR43_001529"
     CDS             complement(9470..10159)
                     /locus_tag="VVR43_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU6149875.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(10177..10818)
                     /locus_tag="VVR43_001530"
     CDS             complement(10177..10818)
                     /locus_tag="VVR43_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU6149876.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(10901..11116)
                     /locus_tag="VVR43_001531"
     CDS             complement(10901..11116)
                     /locus_tag="VVR43_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU6149877.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(11124..11471)
                     /locus_tag="VVR43_001532"
     CDS             complement(11124..11471)
                     /locus_tag="VVR43_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU6149878.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(11476..12591)
                     /locus_tag="VVR43_001533"
     CDS             complement(11476..12591)
                     /locus_tag="VVR43_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU6149879.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(12601..13560)
                     /locus_tag="VVR43_001534"
     CDS             complement(12601..13560)
                     /locus_tag="VVR43_001534"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU6149880.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(13673..14242)
                     /locus_tag="VVR43_001535"
     CDS             complement(13673..14242)
                     /locus_tag="VVR43_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU6149881.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            14370..15041
                     /locus_tag="VVR43_001536"
     CDS             14370..15041
                     /locus_tag="VVR43_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU6149882.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            15025..15843
                     /locus_tag="VVR43_001537"
     CDS             15025..15843
                     /locus_tag="VVR43_001537"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU6149883.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            15840..16736
                     /locus_tag="VVR43_001538"
     CDS             15840..16736
                     /locus_tag="VVR43_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU6149884.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     DIRLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLDDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            16780..17754
                     /gene="pta"
                     /locus_tag="VVR43_001539"
     CDS             16780..17754
                     /gene="pta"
                     /locus_tag="VVR43_001539"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU6149885.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(18069..19109)
                     /locus_tag="VVR43_001540"
                     /pseudo
     CDS             complement(18069..19109)
                     /locus_tag="VVR43_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5682 a         3474 c         4181 g         5772 t
ORIGIN      
        1 taaaataggc tccataatat ctatagggga tttacccact acaaatatta tagaaccgga
       61 ttttgtggta cgacaggcat gtatagcaaa ctgaatctgg aatagcacag catatcttct
      121 aaaatattgt tataaattga tttgaatttc aaaattaaat tgtttgattc ttatttcaat
      181 ttgttatagt atatctgatg tcaaagttct cggcgagtca aatagcgatt cccaagcctg
      241 actatcgtga ggtagcggat taaaatggtc tggggataga ccgttttaag tctgacgctg
      301 gaaataagaa ttgtcagaag aagggatagc gaaatcgtgg ctctacgaac aggaacgtga
      361 taataaggcg tatatagcgg ataagggggc ctcaaactct aaagtccaaa aaggtagtcg
      421 taacctatat gcgtaaatca cgagagtaat tgaattcgta ctaagatttt ctattttcac
      481 tgtaaccttt taacgtcctt atatcttgta tacacgagga aagatgtacg acttatcccg
      541 tgaggtctat cactataaag agaaaacgac agatagaagc gatcctgagt cacggttatc
      601 tttaaaatag attgtctgat aggatgctag cctgaaaacg tcttgttcat gaaatatagg
      661 gacggtatgt ataaaacgct tctgtgaact gagagaaggg ggagaagttc ttgataaaat
      721 ttagttgaac agccgtattc cgatacttag ataagagatc tagtcttagc tcctactcgg
      781 tttcagagga taaaaaaggg caatagcgat tcgagaaaga ttatactctt cgaaaatctc
      841 ttcaaatcac gtcaatatcg ccttgccgta cgtgtaggat actgactacg tcagttccat
      901 ctacaacctc aaaacagtgt tttgagcaac ctgcggctag tttcctagtt tgatctttga
      961 tttttattga gtattagtaa ttcagttact aactcgtcaa ctctgattta tccaataaaa
     1021 ttgaaaagga tggaaaaaag gataaattta tgatatactt tattttgaag accttattag
     1081 aaatcttgaa agagtattga aaacttagaa tgagaaaaat tgttatcaat ggtggattac
     1141 cactgcaagg tgaaattact attagtggtg ctaaaaatag tgttgtggcc ttaattccag
     1201 ctattatatt ggctgatgat gtggtgactt tggattgtgt tccagatatt tcggatgtag
     1261 ccagtcttgt cgaaatcatg gaattgatgg gagctactgt taagcgttat gacgatgtct
     1321 tggagattga tccaagaggt gttcaaaata ttccaatgcc ttatggtaaa attaacagtc
     1381 ttcgtgcatc ttactatttt tatgggagcc tcttaggccg ttttggtgaa gcgacagttg
     1441 gtctaccggg aggatgtgat cttggtcctc gtccgattga cttacacctt aaggcgtttg
     1501 aagctatggg tgccactgct agctacgagg gagataacat gaagttatct gctaaagata
     1561 caggacttca tggtgcaagt atttacatgg atacggttag tgtgggagca acgattaata
     1621 cgatgattgc tgcagttaaa gcaaatggtc gtactattat tgaaaatgca gcccgtgaac
     1681 ctgagattat tgatgtagct actctcttga ataatatggg tgcccatatc cgtggggcag
     1741 gaactaatat catcattatt gatggtgttg aaagattaca tgggacacgt catcaggtga
     1801 ttccagaccg cattgaagct ggaacatata tatctttagc tgctgcagtt ggtaaaggaa
     1861 ttcgtataaa taatgttctt tacgaacacc tggaagggtt tattgctaag ttggaagaaa
     1921 tgggagtgag aatgactgta tctgaagaca gcatttttgt cgaggaacag tctaatttga
     1981 aagcaatcaa tattaagaca gctccttacc caggctttgc aactgatttg caacaaccgc
     2041 ttacccctct tttactaaga gcgaatggtc gtggtacaat tgtcgatacg atttacgaaa
     2101 aacgtgtaaa tcatgttttt gaactagcaa agatggatgc ggatatttcg acaacaaatg
     2161 gtcatatttt gtacacgggt ggacgtgatt tacgtggggc cagtgttaaa gcgaccgact
     2221 taagagctgg ggctgcacta gtcattgctg ggcttatggc tgaaggtaaa actgaaatta
     2281 ccaatatcga gtttatctta cgtggttatt ctgatattat cgaaaaatta cgtaatttag
     2341 gagcggatat tagacttgtt gaggattaaa ccgtagaggt gtttatgaat atttggacca
     2401 aattagcaat gttttctttt tttgaaacgg atcgcttgta tttgcgtcct ttctttttta
     2461 gtgatagtca ggacttccgc gagatagctt caaatccaga aaatcttcaa tttattttcc
     2521 caacgcaggc aagtctggaa gaaagtcaat atgcactggc caattacttt atgaagtccc
     2581 ctttgggagt gtgggcaatt tgtgaccaga aaaatcaaca aatgattggt tctattaaat
     2641 ttgagaagtt agatgaaatc aaaaaagaag ctgagcttgg ctattttttg agaaaagatg
     2701 cttggtcgca aggatttatg acagaggttg ttagaaaaat ttgtcagctt tcttttgagg
     2761 aatttggctt aaaacaatta tctatcatta cccaccttga aaataaagct agccaaagag
     2821 ttgctcttaa gtctggattt agtttgttcc gtcagtttaa gggaagtgat cgttacacaa
     2881 gaaaaatgcg ggattatctt gaatttcggt atgtaaaagg agagttcaat gagtaagcat
     2941 caggaaattc taagctattt ggaggaatta ccagtaggta aaagggtcag tgttcgtagc
     3001 atttcgaatc atctaggagt tagtgatgga acagcctatc gggctattaa agaagctgaa
     3061 aaccgtggaa ttgtggagac ccgtcctaga agtggaacaa ttcgtgttaa atcccagaaa
     3121 gttgctatag agagattaac gtttgctgaa attgcagaag tgacttcttc tgaggttctg
     3181 gctgggcaag aaggtttaga gagagaattt agtaagtttt caattggtgc catgactgaa
     3241 caaaatatct tgtcttacct tcatgatggg gggctcttga ttgtcggaga ccgaacccgt
     3301 attcagttgc tagccttgga aaatgaaaat gcagttctgg ttacaggggg atttcaggtt
     3361 catgatgatg tgcttaaact ggccaatcaa aaagggattc ctgttctaag aagtaagcat
     3421 gataccttta ccgtcgcgac catgatcaat aaagccttgt caaatgtcca aatcaagact
     3481 gatattctga cagttgagaa actttatcgc cctagtcatg agtatggttt tctgagagag
     3541 acagatacag ttaaagatta tttggacttg gttcgtaaga atcgtagcag ccgtttccct
     3601 gttatcaatc aacatcaggt cgttgttggc gttgtaacca tgagagacgc tggtgataaa
     3661 tcaccaagca cgacaattga taaggttatg tctcgtagtc tatttttggt tggattatcg
     3721 acaaatattg ccaatgtgag tcaacggatg atcgcagaag actttgaaat ggtaccagtt
     3781 gttcgaagca atcaaacttt gcttggcgtt gtgacgcgac gagatgtcat ggagaagatg
     3841 agccgttccc aagtttcggc tctaccaact ttttctgagc agattggaca aaagctctct
     3901 tatcaccatg atgaagtagt cattacagtg gaacccttta tgctagaaaa aaatggagtt
     3961 ttggctaatg gtgtattggc agaaattctg acccacatga cccaagattt agttgttaat
     4021 agtggtcgca atctcattat cgagcagatg ctaatctact ttttgcaggc tgttcagata
     4081 gatgatatat tgcgcattca ggcacggatt attcatcata cgagacggtc agctataatt
     4141 gattacgata tttatcatgg tcaccagatt gtttcaaaag caaatgtgac tgttaaaatt
     4201 aattagaaac taggagaaaa gatgataaca ttaaaatcag ctcgtgaaat cgaagctatg
     4261 gacaaggctg gtgattttct agcaagtatt catataggct tacgtgattt gattaagcca
     4321 ggcgtagata tgtgggaagt tgaagaatat gtccgccgtc gttgtaaaga agaaaatttc
     4381 cttccacttc agattggggt tgacggtgcc atgatggact atccttatgc tacctgttgc
     4441 tctcttaacg atgaagtggc tcacgctttc cctcgtcatt atatcttgaa agatggtgat
     4501 ttgctcaaag ttgatatggt tttgggaggt cccattgcta aatctgacct aaatgtctca
     4561 aaattaaact tcaacaatgt tgaacaaatg aaaaaataca ctcagagcta ttctggtggt
     4621 ttagcagact catgttgggc ttatgctgtt ggtacaccgt ccgaagaagt caaaaacttg
     4681 atggatgtaa ccaaagaagc tatgtacaag ggtattgagc aagctgttgt tggaaatcgt
     4741 atcggtgata tcggtgcggc tattcaagaa tacgctgaaa gtcgtggtta cggtgtagtg
     4801 cgtgatttgg ttggtcatgg tgttggccca actatgcacg aagaaccaat ggttcctaac
     4861 tatggtattg caggtcgtgg actccgtctt cgtgaaggaa tggtcttaac cattgaacca
     4921 atgatcaata caggcgattg ggaaattgat acagatatga aaactggttg ggcgcataag
     4981 accattgacg gtggattgtc atgtcagtat gaacaccaat ttgtcattac gaaagatgga
     5041 cctgttatct tgactagcca aggtgaagaa ggaacttatt aataaaaagt gaaaagacta
     5101 ctggaagttt attttgataa aaaatccagt agatcttttc ataataaaac gcattgtatc
     5161 aagtgttagg ggctgatatc atgcgttttt ctgcttttaa gattttttcc aactctgttt
     5221 gtaagcgcat cataacaaag ggtctaggat tcagggctct cctcctatat actattagta
     5281 aagtaaaact aagagaggat attttagtgt cgcagtctat tgttcctgta gagattccac
     5341 aatattgtcg ttttgattct aaaaagagaa atggaattct gtttaacgtt cgtattgcca
     5401 atcttaaatt tacctttttt agattagact tcctgcgaaa taaaatatgg tatagtagtt
     5461 ctatgaatga tgaagcaagt aaacaactaa ctgatgcacg atttaagcgt cttgttggtg
     5521 ttcagcgcac gacttttgaa gagatattag ctgtattaaa aacagcttat caacttaaac
     5581 acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga ccttcttatg tccactcttc
     5641 aatatgtgcg agaatatcga acttatgaac aaattgcggc tgattttggt attcacgaaa
     5701 gcaacttaat ccgtcggagc caatgggttg aagtaactct tgttcaaagt ggtgttacga
     5761 tttcaagaac tcctctcagt tctgaggaca cggtaatgat tgatgcgacg gaagtacaaa
     5821 tcaatcgccc taaaaaaaga attagcgaat cattctggta aaaagaaatt tcacgctatg
     5881 aaggctcaag cgattgtcac aagtcaaggg agaattgttt ctttggatat cgctgtgaac
     5941 tatagtcatg atatgaagtt gttcaaaatg agttgcagaa atatcggaca agctggtaaa
     6001 atcttggctg acagtggtta tcaagggctc atgaagatat atcctcaagc acaaactcca
     6061 cgtaaatcca gcaaactcaa gccgctaaca gctgaagata aagcctgtaa ccatgcgcta
     6121 tccaaggaga gaagcaaggt tgagaacatc tttgccaaag taaaaacgtt taaaatgttt
     6181 tcaacaacct atcgaaatca tcgtaaacgc ttcggattac gaatgaattt gattgctggt
     6241 attatcaatc atgaactagg attctagttt tgcaggaagt ctattgaggt attgagctag
     6301 tttatgaaaa aattgggtga aaaagtcgag tgttttagaa acccacagtg tagtattcta
     6361 gtttcaatcc actatatttt gctactcccc gtaaagtttc tattttccct gatttctgat
     6421 ataatagaaa tattgacttc aagagtaagg aagagaagat gaacgcatta ttaaatggaa
     6481 tgaatgaccg tcaggctgag gcggtgcaaa cgacagaagg tcccttgcta atcatggcag
     6541 gggctggttc tggaaagact cgtgttttga cccaccgtat cgcttatttg attgatgaaa
     6601 agctggtcaa tccttggaat atcttggcca ttacctttac caacaaggct gcgcgtgaga
     6661 tgaaagagcg tgcttatagc ctcaatccag cgactcagga ctgtctgatt gcgaccttcc
     6721 actccatgtg tgtgcgtatt ttgcgtcgcg atgcggacca tattggctac aatcgtaatt
     6781 ttacaattgt ggatcctggt gaacagcgaa cgctcatgaa acgtattctc aaacagttga
     6841 acttggatcc taaaaaatgg aatgaacgaa ctattttggg gaccatttcc aatgctaaga
     6901 atgatttgat tgatgatgtt gcttatgctg cccaagctgg cgatatgtat acgcaaattg
     6961 tggcccagtg ttatacagcc tatcaaaaag aacttcgtca gtctgaatcc gttgactttg
     7021 atgatttgat tatgctgacc ttgcgtctct ttgatcaaaa tcctgatgtt ttgacctact
     7081 accagcaaaa attccaatac atccacgttg atgagtacca agataccaac cacgctcagt
     7141 accaattggt caaactcttg gcttcccgtt ttaaaaatat ctgtgtggtt ggggatgcgg
     7201 accagtctat ctacggttgg cgtggtgctg atatgcagaa tatcttggac tttgaaaagg
     7261 attaccccaa agccaaggtt gttttgttgg aggaaaatta ccgctcaacc aaaaccattc
     7321 tccaagcggc caacgaggtt attaaaaata ataaaaatcg ccgtcctaaa aatctctgga
     7381 ctcaaaacgc tgatggggag caaatcgttt actatcgtgc cgatgatgag ctggatgagg
     7441 ctgtatttgt agccagaacc atcgatgaac ttagtcgcag tcaaaacttc cttcataagg
     7501 attttgcagt tctctatcgg actaatgccc agtcccgtac aattgaggaa gccctgctca
     7561 agtctaacat tccttatacc atggttggcg gaaccaaatt ctacagccgt aaggaaattc
     7621 gcgatattat tgcttatctc aaccttattg ctaatttgag tgacaatatt agttttgagc
     7681 gtattatcaa cgagcctaaa cgtggaattg gtctaggtac agttgagaaa atccgtgatt
     7741 ttgcaaattt gcaaaatatg tctatgctgg atgcttctgc taatattatg ttgtctggta
     7801 tcaagggtaa ggcagcccaa tctatctggg attttgccaa tatgatgctt gatttgcggg
     7861 agcagctaga ccacttaagc attacagagt tggttgagtc cgtcctagaa aaaacaggtt
     7921 atgtcgatat tcttaacgcc caagcgactc tagaaagcaa ggcacgggtt gaaaatatcg
     7981 aagagtttct ttctgttacg aagaactttg atgacaccac ggatgtgaca gaagaggaaa
     8041 ctggtctgga caaactgagt cgtttcttaa atgacttggc tttgattgcc gacacagatt
     8101 caggtagtca ggagacatca gaagtgacct tgatgaccct gcatgctgcc aaaggtctcg
     8161 aatttccagt tgtctttttg attgggatgg aagaaaatgt ctttccactt agtcgtgcga
     8221 ctgaagatcc agatgaatta gaagaagagc gccgtctagc ctatgtaggt atcacgcgtg
     8281 cagagaaaat tctctatctg accaatgcca actcacgctt gctttttggt cgtaccaatt
     8341 ataaccgtcc gactcgtttt attaacgaaa tcagttcaga cttgcttgag tatcaaggtc
     8401 tggctcgtcc tgcaaataca agctttaagg catcatatag cagtggtagt atttcctttg
     8461 gtcaaggtat gagtttggct caggctcttc aagaccgtaa acgcggtgct gccccaaaat
     8521 caatccagtc aagcggtctt ccatttggtc aatttacagc tggcgcaaaa tcagcatcta
     8581 gcgaggcaaa ttggtccatt ggtgacattg ctctccacaa gaaatgggga gagggaactg
     8641 ttctggaagt ttcaggtagc ggtgctaggc aggaattgaa aatcaatttc ccagaagtag
     8701 gtttgaaaaa acttttagcc agtgtggctc caattgagaa aaaaatctaa ttttccatcc
     8761 ttctcacgaa taataaagtg aggaggattt ttatgtacag tatttcattc caagaagatt
     8821 cactattacc aagagaaagg ctggccaagg aaggagttga agcgcttagt aaccaagagt
     8881 tgctagctat tttactcagg acaggaacac gtcaagctag cgtttttgaa attgcccaaa
     8941 aagtcttgaa caatctttca agcctaacgg atttgaaaaa aatgaccctg caggaattgc
     9001 agagtttgtc tggtattggg cgtgttaagg ccatagaatt acaagctatg attgaactgg
     9061 ggcatcgtat tcacaaacac gagactcttg aaatggaaag tattctcagc agtcaaaagt
     9121 tggccaagaa gatgcagcag gaattagggg ataaaaaaca agagcacctg gtggcactct
     9181 atctcaatac tcaaaatcaa atcatccatc agcagaccat ttttatcggt tctgtaactc
     9241 gtagtatcgc tgaaccgcga gagattctgc actatgcaat caagcatatg gcgacttctc
     9301 ttatcttggt ccacaatcat ccttcaggag cggtagcgcc tagccaaaat gatgatcatg
     9361 tcactaaact tgttaaagaa gcctgcgaac tgatggggat tgttctcttg gaccatttga
     9421 ttgtctctca ttctaattac tttagttatc gtgaaaagac agatttaatc taaagttcat
     9481 taacgacata gtcaaagagt ttcttatctt tgggacgatt ttcaaaaaga agttctggat
     9541 gccattggac accgagaaag gcgacatcat ccgtactcat gacagcctca atgataccat
     9601 ctttaggatc atgagccaca acttttaaat ttggtgctaa gtccttgatg ctctggtggt
     9661 ggaaggagtt gatatgagag atttctccat agatttcttg gagaacggta tctggttctg
     9721 ttaccaagcg ttgagttgtg tactcaacag aagaatcctg ccaatggtct tcgatatctt
     9781 ggtacaaagt tccacccatg gcaacgttaa agagttgggt accacggcag acagagaaaa
     9841 tgggcttttt ctgtttaata gcttccttga tgagggccag ttcgaagata tctctttgaa
     9901 ggtgataatc atcgctatca atggttttgg gttcgccata gaattttgga tcgacatttt
     9961 gcccacctgt caagatgagc ttgtcaatca aactgatata gtggcaggcc atttcttgat
    10021 caccaatcgg taggatgatg ggaatccctc cagcatcttt aacgccttca acaaagcctt
    10081 ttgctgcgta gctcatcatg atgtcatcat ctggatgagt tttttcgttt cctgtaatcc
    10141 caataactgg ttttttcata aaatgatttt cgctttctaa tcctcttttc gcatgaagta
    10201 gaggagggtt tggagttcac ttgtcaaatc gacatactga acgaccacgt cttttggtaa
    10261 atgcagatgg actggtgaaa aactgagaat tcctttcaca ccagcatcaa ccaagagatt
    10321 agcaacctct tgtgacttga cgctgggaac agttaggata gcagtcttca catcagcatc
    10381 cttgatttta tccttgatct gagaaatccc gtaaatggga atcccgtcag gagtttgggt
    10441 accgacttca ggatggtcgt ctaggtcaaa ggccatgata atcttcatct tgttacgttc
    10501 gtggaagcgg tagtggagaa gggcatggcc catatttcca ataccaacca gcatgacatt
    10561 ggtaatagag ttgtcattga gcaaatcggc aaaaaatgtc attagttttt tgacatcata
    10621 gccaaaacca cgacgaccaa gttcaccaaa ataggaaaaa tcacgacgta cggtcgctga
    10681 atcaataccg atagcctctg caatttgctt agagttggca cgttcaatct tttctgcatg
    10741 aaatctctta aaaattcgat agtagagaga gagtcttttt gctgtagctt ttggaatagc
    10801 aaactgttta tctttcacaa aatcacaacc tttctattct tctattttat agaaacattg
    10861 tgaaaaaatc aacaaaaata agaaaaaact aagaaaaatc ttagttttga tgtaaaaaat
    10921 ctgcatgaga tagaaaacgg tagaggtctc cgaccagccc ctgataaact tttttgcccc
    10981 taaaagtcag agaagtcaca taaagtgtat ctggtaaggt tacacatcct gacaaagtca
    11041 acatgagagc ctcatgatcc tcatacttga gagtacgctc tacatgatag cagtccttat
    11101 aggtcagttc aaacattttg gctctatctt tccgattttg taaagacacc acgttctacc
    11161 aagctatcca tgaggaagta gaatttttcc tgatgaatat ggtggtcttc tgatttgaaa
    11221 atatcaacta gacgaaggcc aaacttgtca gtgatattga ttttagcccc tgtaagttcc
    11281 ttgttaatga tgattttgag ttggaagcct tcaccgctgt ttggcacttt ttccaaaagg
    11341 cgagtcagtt catagttacc aaccttagtt tcaaaaaagg tgttatcttt gagggtgaat
    11401 tttttaacag aagggctaag agtgtaatcg taacgacaat tttttaactg aatgattttt
    11461 tcaaatgcca tatggctaac ctccgataat ttcttttaag gtttttgcga gggtttgtag
    11521 gtcttcaacg gtattttgtg gcgacaaact gatgcgaagg gattccttca agcgttctga
    11581 atttgcgcca tacatggctt taagaacatg gctggattgg acaacgcctg cagtacaggc
    11641 tgagccagta gagattgaaa ttccagctaa atctagccga aggagtaaga ggtcattttt
    11701 ctgaccagga aatccaatat tgagaacata agggagatga tgttttcctc tattcaagta
    11761 atactgaatg ccctccagct ctgccagaaa ggcagtttct agattttgta catgttgaaa
    11821 atgttcttct tgtttttcta ggtcttcttt tagggctgca accatgccta cgatggcagg
    11881 cagattttca gttcctgcac gttttttctg ttcctgatct ccgccatgta gataggaatc
    11941 aaagtccatg ctagatgcgt agagaaaacc gattccctta ggaccatgga atttgtgggc
    12001 agaagcagtg agaaaatcaa tgcccaattc ttctgaatga attgggattt taccaatagc
    12061 ctgaactgca tcaacatgat aggcagcagg gtgttgcttg agtatttggc caatttcagc
    12121 gatgggaagt aggtttcctg tctcattatt ggcaaacata gtagaaacca aaatcgtatc
    12181 gtcacgtaaa gccttttgaa tttgctgggc tgtgatttct tgattttctg gctggataat
    12241 ggttgcttca aacccaaagt gttgaaccaa gtaatcaatt gtttcaagga cagcatggtg
    12301 ctcgatggca gttgtgatga tatgttttcc ttgttcttgg tgacgaagac agtagccaat
    12361 gatggtagta ttattgcctt cagtcccacc agaagtgaaa aagatatgtt gaggttttgt
    12421 ccttagtaac tgggctagtt cctgacgggc ttctcgcaag agtttgccag cttgacgacc
    12481 atgaccatga atactagaag gatttccgtg ggtttcttgc ataaccttgg tcatagctga
    12541 aatagcaact gctgacatag gagtcgttgc agcattgtcc aaataaatca aagaatcacc
    12601 ttatttcttt ttattgtagg caaagagtgg gctgactggt tttctttcgt gaatacggac
    12661 gatagcatca ccaattaact cactagcagt gatgtagcat acatttttag gagttttttc
    12721 ttttgttgct actgaatcag tcacaagaat ttctttaata ttagtattgt caagaagctc
    12781 agcagctccc tcgacgaaga gaccgtggct agaaacagca taaatttctg tagctccttc
    12841 acgttcaacg attttagaag cttcagagaa ggtacgtcct gtatttaaaa tatcatcaat
    12901 caagatagct ttcttacctt caacatcacc aataatataa ccttcgttac gagttgcatc
    12961 gtcttgaggg tagtcgataa tggcgatagg agcatcaaga tattcagcca ggctacgcgc
    13021 acgtttgaca cctgaatttt tagggctaac gacaacaaca tctgaaccaa gcaatccttt
    13081 atcgcagtaa tgttttgcga ataggggaac agtgaaaaga ttatccactg gaatatcaaa
    13141 gaaaccttga acctgaacgg catgcaaatc aagagtcagg atacgatcaa ctccagcctt
    13201 aaccagcata ttggcaacta gttttgctgt aagtggctca cgaggacaag caatgcggtc
    13261 ttgacgtgca tagccaaaat atggaaggac aacgttgata ctgtgggcac ttgcacgcac
    13321 acaagcatcg accatgatta acaattccat taggtggttg ttgacaggga aacttgttga
    13381 ttggatgatg taaacatcat aaccacggac actttcttcg atatttactt ggatttctcc
    13441 gtctgaaaat tgacgtgatg atagttttcc aagtgggaca ccaacagctt gggcaatttt
    13501 ttgtgcaatc tcttggttag agttgagtgc gaaaagtttc atgttttttc tatctgacat
    13561 tatagaccgt cctctgtaaa ctttataaat cctagttata tttaccttac atatatgaac
    13621 tgggatttgt gtatttttat cttttctatt ttaccaaaaa atggagatta tttcagctat
    13681 ttttcatact tttgacaaat cgaaccaatt ttgaaggagc tttttggtag gaaatctgat
    13741 ttttctctaa aaattgtcgg aaatcctgtt tgccttgctc atgattttcc acttcaagct
    13801 ccaattcgta atctgtcata tcaaagtatc ggctctgatc cagtgccatg agaccaatag
    13861 ctgttttcat ttcatagcga agcgttgtta gacaaccaag aacctgccag ttcttacttt
    13921 ggataccatg tttcgccaat tcatccagta ctagcccttg aggaagttct tccttactca
    13981 gatagttctc agcatctttt agttgcaatt tttggttgta ttccatgttt ccaacactct
    14041 gcgggacttt gagtgtcaac tcagcccagt cttcaaaggt tcgaatgcgc atagcgactt
    14101 tcttttctcg cagttcaaaa tcaggcgtgt cgatgtagta atttgtttga agaacaggag
    14161 tgacacctgt gaactggtct tttagacgat tgtattcatc ttttttcaat agtgttttca
    14221 attcaatttc taaatgtttc atttttctta ccttttttta tcgttgaaag cggatttatg
    14281 gtataataag cattgtattt attgtatatg aatctggaga aaaaatcaaa gatatttttg
    14341 acggataata tgagaacaag ggagaatata tgaccttaga atgggaagaa tttctagatc
    14401 cttacattca agctgttggt gagttaaaga ttaaacttcg tggtattcgt aagcaatatc
    14461 gtaagcaaaa taagcattct ccaattgagt ttgtgaccgg tcgagtcaag ccaattgaga
    14521 gcatcaaaga aaaaatggct cgtcgtggca ttacttatgc gaccttggaa cacgatttgc
    14581 aggatattgc tggcttacgt gtgatggttc agtttgtaga tgacgtcaag gaagtagtgg
    14641 atattttgca caagcgtcag gatatgcgaa tcatacagga gcgagattat attactcata
    14701 gaaaagcatc aggctatcgt tcctatcatg tggtagtaga atatacggtt gataccatca
    14761 atggagctaa gactattttg gcagaaattc aaattcgtac tttggccatg aatttctggg
    14821 caacgataga acattctctc aactacaagt accaagggga tttcccagat gagattaaga
    14881 agcgactgga aattacagct agaatcgccc atcagttgga tgaagaaatg ggtgaaattc
    14941 gtgatgatat ccaagaagcc caggcacttt ttgatccttt gagtagaaaa ttaaatgacg
    15001 gtgtaggaaa cagtgacgat acagatgaag aatacaggta aacgaattga tctgatagcc
    15061 aatagaaaac cgcagagtca aagggttttg tatgaattgc gagatcgttt gaagagaaat
    15121 cagtttatac tcaatgatac caatccggat attgtcattt ccattggcgg ggatggtatg
    15181 ctcttgtcgg cctttcataa gtacgaaaat cagcttgaca aggtccgctt tatcggtctt
    15241 catactggac atttgggctt ctatacagat tatcgtgatt ttgagttgga caagctagtg
    15301 actaatttgc agctagatac tggggcaagg gtttcttacc ctgttctgaa tgtgaaggtc
    15361 tttcttgaaa atggtgaagt taagattttc agagcactca acgaagccag catccgcagg
    15421 tctgatcgaa ccatggtggc agatattgta ataaatggtg ttccctttga acgttttcgt
    15481 ggagacgggc taacagtttc gacaccgact ggtagtactg cctataacaa gtctcttggc
    15541 ggtgctgttt tacaccctac cattgaagct ttgcaattaa cggaaattgc cagccttaat
    15601 aatcgtgttt atcgaacact gggctcttcc attattgtgc ctaagaagga taagattgaa
    15661 cttattccaa caagaaacga ttatcatact atttcggttg acaatagcgt ttattctttc
    15721 cgtaatattg agcgtattga gtatcaaatc gaccatcata agattcactt tgtcgcgact
    15781 cctagccata ccagtttctg gaaccgtgtt aaggatgcct ttatcggtga ggtggatgaa
    15841 tgaggtttga atttatcgca gatgaacatg tcaaggttaa gaccttttta aaaaagcacg
    15901 aggtttctaa gggattgctg gccaagatta agtttcgagg tggagctatt ctggtcaata
    15961 atcaaccgca aaatgcaacg tatctattgg acgttggaga ctacgttacc attgacattc
    16021 ccgctgagaa aggctttgaa accttggagg ctattgagct tccattagat attctctatg
    16081 aggatgacca ctttctagtc ttgaataaac cctatggagt ggcttctatt cctagtgtca
    16141 atcactctaa taccattgcc aattttatca agggttacta tgtcaagcaa aattatgaaa
    16201 atcagcaggt tcacattgtt accagactag atagggacac ttctggcttg atgctctttg
    16261 ccaagcacgg ttatgcccat gcacgattag acaagcagtt gcagaagaaa tctatcgaga
    16321 aacgctactt tgctttggtt aagggagatg gacatttgga gccagaaggg gaaattattg
    16381 ctccgattgc gcgtgatgaa gactccatta ttaccagacg ggtggctaaa ggtggaaaat
    16441 atgcccatac ttcctacaag attgtagctt cttatggaaa tatccacttg gtcgacattc
    16501 ggctgcacac tggtcgaacc caccaaattc gagtccactt ttctcatatt ggttttcctt
    16561 tgttgggcga tgatttgtac ggtggtagtc tggacgacgg catccaacgt caggccctgc
    16621 attgccatta cctatccttt tatcatccat ttttagagca agatttgcag ttagaaagtc
    16681 ccttgccgga tgatttcagc aaccttatta cccagttatc aactaatact ctataaaaac
    16741 tgtttcagag tataattatt atcttaaagg agaaaactca tggaagtttt tgaaagtctc
    16801 aaagccaacc ttgttggtaa aaatgctcgt atcgttctcc ctgaagggga agagccacgt
    16861 attcttcaag cgactaaacg tttggtaaaa gaaacagaag tgattcctgt tttgttagga
    16921 aatcctgaaa aaattaaaat ttatcttgaa attgaaggga tcatggatgg ttatgaggtc
    16981 atcgaccctc aacattatcc tcaatttgaa gaaatggttt ctgccttggt ggagcgtcgc
    17041 aagggcaaaa tgactgaaga agatgtacgc aaggttttgg ttgaagatgt caactacttt
    17101 ggtgtgatgt tggtttactt gggcttggtt gatggaatgg tgtcaggagc gattcactca
    17161 acagcttcaa cagttcgtcc agctctacaa atcatcaaaa ctcgtccaaa tgtaactcgt
    17221 acttcaggag ccttcctcat ggttcgtggt acggaacgtt acctatttgg agactgtgcc
    17281 attaacatca atccagatgc agaagccttg gctgaaattg ccatcaactc agcaatcaca
    17341 gctaagatgt ttggcatcga acctaaaatt gccatgttga gctattctac taaaggttca
    17401 gggtttggtg aaagcgttga taaggtcgtt gaagcaacta aaattgctca cgacttgcgt
    17461 cctgaccttg aaatcgatgg tgagttgcaa tttgatgcag cctttgttcc tgaaactgca
    17521 gctctgaaag ctcctggaag tacggtagct ggtcaagcaa atgtcttcat cttcccaggt
    17581 atcgaggcag gaaatatcgg ttacaagatg gctgaacgcc tgggtggctt tgcggctgta
    17641 ggacctgttt tgcaaggttt aaacaagcca gttaatgatc tttctcgtgg atgtaatgca
    17701 gatgatgttt acaagttgac cctcatcaca gcagctcaag cagttcatca atagtgaaaa
    17761 ctataaagcg atatactatg ctatactgta gttatgaaac tatgtacgaa aagcactgcc
    17821 attaattcct gagaactaaa ttactgattg gtgtcaaaaa ggaaaacttc caagcgatga
    17881 tatcctgtct atacacgacc tatagaaatc tgtaatatgt atgtccgtaa aacgataatt
    17941 tccctttttg attttaaatg agtatgaaaa gagaattttt tcatgagaaa acgcataata
    18001 ttaagtgtct tgacacctgc tattatgcgt tttctggctc tttgtcaact gtagtgggtt
    18061 gaagtcagct aagctcgaga aaggacaaat ttcgtccttt cttttttgat gttcagagcg
    18121 ataaaaatcc gttttttgaa gttttcaaag tttcgaaaac caaaggcatt gcgtttgata
    18181 agtttgatga gattattggt cgcttccaat ttggcgtttg aatagggtag ttgaagggcg
    18241 ttgacgattt tctctttgtc ctttagaaag gttttaaaga cagtctgaaa aagaggatga
    18301 acctgcttta gattgtcctc aataagcccg aaaaatttct ctggttcctt attctggaag
    18361 tgaaaaagca agagctgata gagttgatag tggtgtttca agtcttccga ataactcaaa
    18421 agcttgttta aaatctcttt attggttaag tgcatacgaa aagtaggacg ataaaatcgc
    18481 ttatcactca gtttacggct atcctgttga atgagtttcc agtagcgctt gatagccttg
    18541 tattcatggg attttcgatg aaactgattc atgatttgaa cacgcacacg actcatagca
    18601 cggctaagat gttgtacaat gtgaaagcga tcaagaacga ttttagcatt cgggagtgaa
    18661 acagtctggg agactgtttc agcctgagcc tagaaatttg aaagcgaagc tgtttagcca
    18721 agccatagta agggctaaac atatccatag taatgatttt gacgcgacat cggacggctc
    18781 tatcgtagcg aagaaagtga tttcgaatga tagcttgtgt tcttccctca agaacagtga
    18841 tgatattgag cttgtcaaaa tcttgcgcaa taaagctcat ctccatctcc cgattgaaac
    18901 agtcactacc cggactgttt caacgtccca agacataatc tcaggaagac aagaaaaatc
    18961 atgtttaaag tgaaaatcat tgagcttacg aataacagtt gaagttgaga tgaaaagctg
    19021 atgggcaata tcagtcatag aaatcttttc aattaacttt tgagcaatct tttggttgat
    19081 gatacgaggg atttggtgat ttttcttta
//
LOCUS       DAVHSY010000034        18863 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.035, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000034 DAVHSY010000000
VERSION     DAVHSY010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.035"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(110..472)
                     /locus_tag="VVR43_001541"
     CDS             complement(110..472)
                     /locus_tag="VVR43_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149886.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(763..2643)
                     /locus_tag="VVR43_001542"
     CDS             complement(763..2643)
                     /locus_tag="VVR43_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU6149887.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLATVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2637..3506)
                     /locus_tag="VVR43_001543"
     CDS             complement(2637..3506)
                     /locus_tag="VVR43_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6149888.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3590..6235)
                     /locus_tag="VVR43_001544"
     CDS             complement(3590..6235)
                     /locus_tag="VVR43_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU6149889.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGHPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNRPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDDTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEYALECHQAQERFSAYRSAKALQTPFTSLQLARQEGS
                     VAATGSLLSHSVLSIPQICPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLDPQEIRTEFIKKEEI"
     gene            complement(6326..7606)
                     /locus_tag="VVR43_001545"
     CDS             complement(6326..7606)
                     /locus_tag="VVR43_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU6149890.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDSLLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPFQLAYLLWKETGETGQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADTKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7777..9861
                     /locus_tag="VVR43_001546"
     CDS             7777..9861
                     /locus_tag="VVR43_001546"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU6149891.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALLNLPQEDFDSCKSSAQADWENLLHRFDIIEIGEADRTFFDHCLYRLFLFPQTF
                     YEINESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(9901..11580)
                     /locus_tag="VVR43_001547"
     CDS             complement(9901..11580)
                     /locus_tag="VVR43_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU6149892.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGACLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDDLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKT
                     PRLSQTVAVQGLAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12336..13565
                     /gene="arcA"
                     /locus_tag="VVR43_001548"
     CDS             12336..13565
                     /gene="arcA"
                     /locus_tag="VVR43_001548"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU6149893.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13623..14639
                     /gene="argF"
                     /locus_tag="VVR43_001549"
     CDS             13623..14639
                     /gene="argF"
                     /locus_tag="VVR43_001549"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU6149894.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14804..15751
                     /gene="arcC"
                     /locus_tag="VVR43_001550"
     CDS             14804..15751
                     /gene="arcC"
                     /locus_tag="VVR43_001550"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU6149895.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            15962..17473
                     /locus_tag="VVR43_001551"
     CDS             15962..17473
                     /locus_tag="VVR43_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU6149896.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17495..18826
                     /locus_tag="VVR43_001552"
     CDS             17495..18826
                     /locus_tag="VVR43_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU6149897.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQLKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHKRSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
BASE COUNT         5278 a         4288 c         3901 g         5396 t
ORIGIN      
        1 cttcggatta cgaatgaatt tgattgctgg tattatcaat catgaactag gattctagtt
       61 ttgcaggaag tctattgaaa tactaagcct acacagactg atttcaattt taccattctt
      121 catagtcaaa accatcataa tctggatatt gttctggcga cgttccaacc gaacgtacga
      181 gataagcttc ttcgtcctct gtctcgattt ctctcagcac ttggcattca aaacgccatt
      241 catcaccgaa gtcgaaaata aacttaaatt tttgtttgac acttaggcta tccagataga
      301 cattttctgt gtaacgttct tcaacatcgt cactaacaaa gctaagaaag taagaatctg
      361 catgactcca ctcaacatta tccatgaaaa atgcgtgagc atgatcattt gcaaaatcaa
      421 aactccataa aatcacatct gctagttccg ctaacgtttt tgtttttgga atctatatat
      481 gtcggtagca acctttttta aatttgacgg aaatgaccca agcttctaca gatgctggct
      541 tttcagcttc tatttcttgt tttactaatt ttaactgtag catttgaaac cagataattc
      601 ttctgtttca cgcgaaacac cctgcgccaa gcaaggtgtt cttgttttta tactcaatga
      661 aaatcaaaga gcaaactagg aagctagctg caggctgctc aaaacactgt tttgaggttg
      721 tagatggaag ctgacgtggt ttgaagagat tttcgaagag tattaagtcg tataaatcgt
      781 cgaagctgtc gcaatggtat gccactggtt agctgtagtt gctgcgaaat ccttgtctgc
      841 gtagaagtca gtaaatggta ggatttcaac ttccagctcg tcgatgcggt caagctggcc
      901 agccagataa acctcgatac ggctttctgc tcgtttgatg cgttgcaaga gtccgcccat
      961 acggatgtca actgtatcca aaccaaagac cttgttttct ttcagccatt ggtgactaaa
     1021 gagggcatgg aagtcttcaa tttggcttct aagttctggt aattcttgtc tggcgatttg
     1081 ttgtaaactt tctttatcat ccgcttggta ggcctgacga atgcgtcgtc ccacatctac
     1141 tttgctactt aaaatagcat tcaactgggc ctgagtttca aagagataag catagtttcc
     1201 agctttttct ttaatgtcag caatagttcc cgccgcctga gcgaagtgtg gcttgtcctg
     1261 ttcaggtgtc atgtgtcggt caagtatcgg acagagaaca tcctgataaa agacatatcg
     1321 gttgggattg atgccactga gattacctgg taggtctggt aagaggttgg caaggtcaat
     1381 ctgcataaaa tcttcaaccg ttagaccagt attggtcttg aagtgcgcag acaaactatc
     1441 taggtcattg cgatagctga gttctgccca gatttgcaag cttggtagga tagagaactg
     1501 ggcagtttca ccaccattgt ctccccaacc cgttacgatg acttctttaa tctgattggc
     1561 acggcaggct ttattagcct cgatagccac tagacggcta aaatggttgt gaggtgtaaa
     1621 gccaatccac ttccaagctc cccctgcaaa tgcaaggtca tggctaatct tgtgatgatt
     1681 gcggaaatta cggttgtatt tttcctcgct atcctgataa taatcccagt aaaccagagt
     1741 cacacggtct ttgagacggt ctaggtagac acgagtttcc tctggaattt ccacatcacg
     1801 atcgtactgg ccatccgctg acatgagttt gaagaacata tcactccaca tctggcagtg
     1861 gaaaccatat ttgtcagcaa tatccagcac gcgctccaag tgttggcaca tgaggagact
     1921 acgatccaca acaccgttca gaatcaggta gcgtcccaaa ccaaccaagt gggcttcgtc
     1981 catcccgata ttgaccttgc gagtcttcag tttagacaac gtggcaaaca tgccatcaat
     2041 caggtcataa accttttctt cgccaatgag aagaatgtcc tctacatcac ggagctcctg
     2101 cacttccttg acaccccatt tgacaaaggc cgacaagtgg gccaaggtct ggatgcatgg
     2161 tacaaaggtc atgtcaaact gttgagcata ggcttcgatt tcctgcaact cctctgctga
     2221 ataagctcca cggaaatagc caaagtaagg ctgtccttca atctggtaag tgtcttccat
     2281 gtaaagctca aaggttgagt agcccatgag agccaagacc tcaatcatct gcttggcaga
     2341 agcgacattc agcaccgcat ttcgagaaca gtcaaccatg taagccaaat cttcgtaagc
     2401 tgcttgttcc tcaatctcta ctttatcagc ttctgctaga actgttgcca acaaggacaa
     2461 ggcacgataa agttggtgag gtttgcggta ggtcaattga tagtgacctt cctcaccctc
     2521 gatagagata gaggcttggt cagactgagt gacagccact tccacatctg gtagagaaat
     2581 atgacctttt aaaacctcaa tagcttgcgt ttgtttggga ctaagtcctg taaatcttac
     2641 cattgctttt cctcctgtag ccagttgaca agagcaccgt agagattggc atctgcgtga
     2701 taggtgcagg cctggataac tggtgcgacc gtgtattctt cgtaggcatc gacaaagtct
     2761 tcaacagcct tcttgacacc ttggataaaa tctggatttt gactgataga gccacccaga
     2821 ctgatgacat ctggatcgat gagatactgg atattgagca agccttgcgc cagattgcgg
     2881 ttcattcgct caatggcttc ttgacaaaga gcattaccag ctgcggcctc ttggtaaatc
     2941 ttgcgaccgt cccaatcagt atgaccagat ttttcaatca cgtatcgtac catattccca
     3001 gttgatgcta gttgcgacca gttattaagt ttttcagcag gggcaagggt tgtcatgtag
     3061 ccaaattctc cacccagacc gtggcgacct cgatgaagtc taccattgat aatcatggct
     3121 ccgccaatcc ctgtcccaat cacgacacag gctgcatttt caagctctgg atgagctagt
     3181 agttcactga gtccaacgca gttggcatca ttttctaaat ggacaggtag ctgataagag
     3241 ctaagcgcct cataccaaga aaagccatgg atgtagggca ccgcactgaa gccatcaatc
     3301 acacctgtct cttgattgac cgcacccgga acgctcatag caatcccact gtaatcctgt
     3361 tctgacaagc gttgatctag ccacgctagt aaatcctcca agttttcagg cgttgaaata
     3421 cttgtcttat ccagtatttt cccatcagga gtcagactgg caaacttaat cccagtccct
     3481 ccgatatcaa tcgttgcaat ggtcattgtt tttaccataa aaaggggcga atcagcagtt
     3541 agttcttact ttttcgcccc tcctttcttt tgatgtttac tttttgaaat taaatttctt
     3601 cttttttgat gaattctgta cgaatctctt gtggatccaa tagtcctgaa tgaactggat
     3661 atggtcgctc aagtaagtca agaatggttt gttggtgttc tgatatgcgc acattttctt
     3721 gactcatatt gtagtaacgg agtacatatc cttcttcatt ttccgccact ttaaaggctg
     3781 ttggacagat ttgcggtatg ctgagaacag aatgactcaa gaggctacca gtcgcagcca
     3841 cgcttccttc ctgtctagca agctgaaggc tggtaaacgg tgtctgcaag gctttggcac
     3901 tacgataggc tgagaagcgt tcttgggctt ggtggcactc aagcgcatac tcgacttcaa
     3961 actcacgcaa gcattgggct tctggtgttg ggaagtagcc ccagtcacct agctcacctg
     4021 atgcacgcaa aatagtcact gcaatggtgt cgtctccaag gatttcgtat tcattcaatc
     4081 ccttgttgga tacagtcaca cctttttcat cgtcatacag actaacaaag gcttgttggt
     4141 gttgaggatt ttcaggattt tcccatgaag cagctggtct gtttggacgt gtcaccacct
     4201 cataaatgct ttcagaatca ttgcttggac gcgtgttatg agtcttgacc aagagacgga
     4261 tacggtgatc cttggcagtg ttagtaaagc gagtcttgaa gcggatttgt ggattgtcaa
     4321 cgaagacagt caactcagtt tccagaggaa tgtttgtcaa ttcttctgac cgtccagcct
     4381 cacgcttcat aaactcgatg ataccttgtt gctcttcttc tagcttttca tccgcgctga
     4441 caggcacggt caattcatgt ttgagcaaga ttttagcata gcaagctgtg ttttccaaga
     4501 cctcgtggcc cttaagctct gcaaagattg gctctgttcc ttttggttgg aaatagatat
     4561 actcgtttcc gatgtcccca cggtcttcaa agcggataaa gtcttcatag gcttcgtgag
     4621 ttgtcttgtc atagactgtg atgttgtcat ccacactcac cgttacgaat ggtgtatcaa
     4681 tcactccgtt ttggtaaata ccctcacggt gttcttgttt tccttccagc aattggaagg
     4741 ttgtccaaga aagcggcgct aggtgaactg gaatggtcac gcgcacttga cgagcaatac
     4801 gagcttggcg gaacttgtct tttggtaaat catactcaaa attagctccg aggtcttcga
     4861 ttgtagcctc tacaggatga ccatccaagt cctccacacg gtaacttggc aagataagag
     4921 cagccatctt tttgtagcct tctgttgggt gcaattcctt gaaatcacaa gtcgccacat
     4981 caatcactgt gctgacagta tcgaccttat catgcaagcc tgtgttaatg acagtaaaga
     5041 gatagtcact ttgagcctta tccgtagcaa ttttaccctt ccactcgttg agcaagttac
     5101 ttttaacaaa gtttcctact tggttgacct tggcaaaacg cgtttccatc tcgcggtgaa
     5161 cttcgtccac gctacagcca cagatactat catgtggcgc gttctgcaaa agtgttttcc
     5221 aagcataggt caactggtcc ttgtggttgt gtccaccagt gataatagtc aagggttcta
     5281 ccacttgctc taggaggttg ctattttctt ggaaggcttg ttttaggtaa atgcgggatg
     5341 aagaagtgtt ggcaagtgtg taccagccat ctgtttcctg actggtcaac tcacctgtaa
     5401 cagttgataa gtgttcagga agcgcacctt ctacagcttg aacatattca tcaaaagaac
     5461 tatgaacaaa gattacatct gggaagagtt catttgccac acgaatggct tcgctcagat
     5521 ttttctgtac aggctggtgg tcacagccgt tcatcatcaa ccattggttg gtcgaagcgt
     5581 aggcacgcac atctgacaat ttttgtttcc agaaggtcaa ggcctcatct ttgtcaactg
     5641 gaatttcatt cccgttactg taccagttgg caaagagaat acctaaaaca cgactaccat
     5701 ccacaccctg ccagtacatt tctgaaaact gggatgtaaa ctgctcatct tcaaggactt
     5761 ggttgtcaaa tccaatcggc ttcacaccac gaccaaaggc cgccacgtga atgcctgatt
     5821 tttgaagaat ttgaggcgct tgtcccatat ttccaaaggt atctggaaag tagccaatct
     5881 gggttgattt accccatttg gcagcttctt gttgaccaat caaggtattg cggacattgg
     5941 cttcactgga gatcaagtag tcatcctgca agatgtaaaa gggaccaatt ttaagtttgc
     6001 cctcgtcaat gtagcgttgg accttgtcac gattttcagg gcgaatttgt aagtagtcgt
     6061 caaggacaat agtttgtcca tccaagtgga aactcttgaa ctcagggtca ttttcaaaga
     6121 gatcaaagag attgtcaaac aattccacca actgcatacg atggctttca aaaggcaagt
     6181 accactcacg gtcccagtga ctatgtgaga taatatgtac aacaacattt tccatgaagt
     6241 aaaacctcat tctaaattta aattttaacg ttttaaatgt aaacttgtga ttctgataag
     6301 aatcggttga gctaaagcga gccccttagc gaatatccaa gtaatccaag accaactcac
     6361 agaacatcat gttagcccag gagaaccatt cacgagagta gagggtcgga tcatctacgt
     6421 ggaagctttc gtgcatgaca cctgtaccac catcgcaggc aaccagctga tccagcaaga
     6481 attttttctc tgccttatct cttgttgtca atccttggat agaaagggcg attggccaga
     6541 tatagcgata gaaggtatga gaacttccga gaccgctagc gtattctcct tggtagaagt
     6601 atggattttc agagctcaaa atggtacgac gagtagcttg atacacttca tcatcgaccg
     6661 aacagtagcc cagatagggc gcagctagta gacttggtac atttggatca tccatgatgc
     6721 tggcatttcc taggccatcc acttcaaaag cgtaaatctt ttcgcccttg ctgttggtgg
     6781 tgtaagcgta gttttcgatt ccttcttgga tttcatcctg aagacgcttg gtatcagcaa
     6841 taacactctg gctatcagct aggtttaatg ctgcgaagat ttcttgcaca taacccaaga
     6901 ctactacagc aaacatattt gacggaatca agtaactata ctggcaacag tcatcactcg
     6961 gacgaaaggc tgaccaagtc atacctgtca ctgcaaagtc aggtccaaag ccatcattta
     7021 ccaaggtgtc ttccttacgg tccgtatctc ggacaaaacg ataaggagag ttcttgtggt
     7081 cttgttcaac tgtccataga tggagaattt ccttagtcgc tgcgacaaaa gtctcatcaa
     7141 actgaccagt ctcgccagtc tctttccaga gaagataagc caactgaaaa ggatagcaaa
     7201 gcgagtccac ctcatacttg cgttcccaaa tccagccatt aaggtcggtg tggtcggtct
     7261 cgtggtgccc cttccagttt tcctctatgt tgaaggaatt ggcataagga tccttgagta
     7321 ccaaggtcat ctgacgtttg accaaacctg caatggtctg acgcaggagg gaatctcttt
     7381 tagccacatg caggtagggt ctgagttggg ctgtcgaatc ccgaagccac atagcaggaa
     7441 tatccccagt caagacaaaa gttgaaccat cttctaagat ttcaaccgta ttgtccaagg
     7501 tatcggtgta gcaacgctca aagacatcaa cccactctgg atggtccttg gcccgctctg
     7561 ctacttcatc cagccactct ctgacgattt ctttcgaata aatcatcgtg caattccctc
     7621 tttcaaacaa gtttcatgtt cagtatatag cttttgagac agaaaataca tacacaaatg
     7681 atagtcattt ttctacaaaa tagttatttt tgaaactcct tttctaaagg ccctcttttt
     7741 ctgatataat gtagaaaaac agctaaagga aagactatga aaccactact tgaaaccatc
     7801 gatacccgct ttggaactac caacaagcat gccttttctc ggggaaatac cctgccatac
     7861 acaggcgtgc cttttgggat gaattacttt gtgccccaga ccagtgacca ggatggatct
     7921 tggttttttg atccgcatct gcctatcttt caggggattc gattaactca ccagcccagt
     7981 ccttggattg gggactactc ttggctcctt ctgacacctg tcaccagtca actgggggga
     8041 gacagcctct ttcaccgcca gtcttcttat gatatagata aagcttgctt ccagcctcac
     8101 tatttgaagc tcttttctct gcgttatcag attgaaaccc agctcacacc gacttgctat
     8161 ggtgcttcta ttcgtttgaa tcaaaagcaa ggcaaagccc tctccctcta tcttcacgca
     8221 gcagatgaac tgacagtaga gcaagtagat aagcggactc ttgccctgcg acaagaaggt
     8281 aaaactgaaa ctaacaaaaa ttcgctaacg atgttcactg ccctgcaaat gaacacggat
     8341 attcttgcca tcagccaaga agctggagac tggcgaattg acttagcaag tagtcaaacc
     8401 gagatgcaac tagccacttc tttcatctct ccttctcaag cactgcttaa tctacctcaa
     8461 gaagattttg atagctgtaa atcaagtgcc caagcggatt gggaaaatct cctccatcgt
     8521 tttgacatta tagagatagg agaggctgac cgaaccttct ttgaccactg cctctacaga
     8581 ctcttcctct tcccacagac tttttatgag attaatgaat cagggcaagc catccacatg
     8641 gatctggcta ctggtactgt caagcctggt gtcctcttta gcaacaatgg tttctgggat
     8701 accttccgca ccaccttccc cctctttgcc cttatcatac cggagcacta tcaacgcttt
     8761 ttagaaggtt tcctcaatag ctaccgcgat actggtttcc ttccaaaatg gctggctcca
     8821 gatgaacggg gtatgatgcc aggtacactt ttagacggta ttatcgcaga tagcgcctgc
     8881 aaggacatgg cccctgacct agaaggagaa ctcttccaag ccatgctcga aacagccagc
     8941 aaagccgacc ctctcggaat caatggccgc cacggactag cccaatacca agaactaggt
     9001 tacctctcta ccgaccacca cgaaagtgtt agccatactc tagactatgc ctatagtgac
     9061 ttttgtatcg ccagctgtgc caaaaaacta gagaacatag aaatcgctga aacctacaag
     9121 gctgcttcac aaaattaccg ccagctattt gacgctgaga caggttacat gcgagcacga
     9181 gacaatcaag gaaactttca ccctgacttc tctccttata gttgggggcg agactacgct
     9241 gaatgctctg ccattcaagc tactttaggc gttctccacg acatccctgg cttaatccaa
     9301 ctgatgggtg gaaaagaaac ctttagcaac tatcttttga aagcctgtca agatgctccc
     9361 ctctttgaaa caacaggcta tggttacgaa attcacgaaa tgagcgagat ggctactgct
     9421 ccttttggac aaatagccat ttccaaccag cctagtttcc acattcctta tctcttccgc
     9481 tacagcgatt accctgacta cactgccctt cttatcaaga cgctccgtca gaaagctttt
     9541 cacccaagtt gggaagccta tcctggagat gaagacaatg gtagtctctc tgcttggtac
     9601 atctggtcag ctctcggatt ttatccaacc tgtccaggaa aaccaagcta tgacctcgga
     9661 atccctctct ttgaccatct acgagtctac ctcgctaaag aagataaatg gctggatatc
     9721 catactaaac aaaaccacaa ccattttaac tttgtcaaag aatgccgact ggacaaaaca
     9781 ctcgtatcaa ctattcaaca ccaagacctc ttaaaagctg aacaactaac tttcaccctc
     9841 agctggttac caagtcacta ataaccaaaa gaacctttgc atcgcgcaaa ggttcttctt
     9901 ttatgaaact tggacttgaa gttgatccac aagctgacca tccaccgtta ggttcagata
     9961 gaaatccaag gttttatctc ctgcgaaata cagggttggt agatgcaaat cttttttgct
    10021 ttcccctgct tggaattgaa ggacttgaat ctcatcctga taggcgacac catggacacc
    10081 tgtccccggt tgaatcgaaa tcttagcctc taaagaggag ctactttcac tacgttcaat
    10141 cctaaaatga agagtctctc cctttgccac agctaggctt ttttctgcaa atgctagccc
    10201 ctgaacagct actgtttgtg ataacctcgg agttttatag agtgaaatct tggtcaacaa
    10261 aggcaaagcc tgtgattctg taatgactac acgtatcttc tgtgcttcaa caactgctcc
    10321 tcgtaagaga cgtttgtaac caacagtatg acccgaacca aactcctgcc agacaccatc
    10381 cacctctact tgcacatgaa aagcagcgat tcgttgccct agcttcaaat cttctcttaa
    10441 ctcaattaca tcaaaagttt taggagaacc taagtcgagt tctaactgga tgggcaagtc
    10501 tgcatcgttt gcccaagagc tggtctcaag gtcgtctgtc aaatggcgac aagcaaagtc
    10561 tgcggaaaga gctggaccag atacctcagc tcccagagcc aaatcttctt tatagagctc
    10621 attgcgatag gtcgcaaatt cataaagtcg ttcaatatcc tttgcatcaa agagcccagc
    10681 ttgattcggc ggaatattaa gcaagagtgg agttcctcgc cctactgagt gaaagtagat
    10741 ttcgaccaac tcctcgagag acttaggatc ctgatcctca tggtagaacc agcctggacg
    10801 gatggaaaca tctgcctctc cgattgaaaa aatcgtgccc gagggatccc cgtgctgaag
    10861 atagttcagc tctgcttctg ttcctagttt atcaggattc accttttgcc acagtggatc
    10921 acctgcatac cctcgttcat tgccaatcca gcggatactg gtgccttctg ttgaaaaaat
    10981 caagcaagcg ccctgcaggt cacgaatggt ttcaaaccat ttttcaaatt cataattaac
    11041 cttttgcgcg ccctctcctc tggcaccatc catccaaacc tcagcaaatt tccctccatt
    11101 tccataggca ggatttgata agatttcctt cagctgagcc agataatagg cattgtagtc
    11161 cgcttctcgg tccacatgat agaggggact atgggcatcc cacggtgaca ggtagacccc
    11221 catatccata tcaaactctg tggcagcttg ggatacttca aggagcaagt cgccctttcc
    11281 tctcctccaa ggactgacct taaccgaata atctgtgtga gctgtcggat aaaggacaaa
    11341 gccatcgtgg tgcttgacca ccaaaatcaa ctttttgaag cccgtttcct tgagcacacg
    11401 aacccactca cgcgcatcca actgactcgg gttaaagcgc tcaggatcct cctgtccagt
    11461 cccccattct tggtcataaa aggtattagg accgaagtgg ataaaagctg ctagttcatc
    11521 tcccagataa gctagctgag tctgacttgg taacggtcca tgcggtttga ttttcttcat
    11581 cgttatatat ctccttcttt agcaacttct cttgttcaca aggttatcca caggttgtgg
    11641 ataataaacc atgatctaac agccagctct ttccaactcc aactggtagg ctcaggattt
    11701 tgctcctcaa tattccctct tcaaacagct ctgtcatatg gttctgctaa cacctctcag
    11761 aatgctactc tccataatta ttctcaggct tctttcaggt cattgtgtga agaccattca
    11821 ctctccagac ttttccacag attgtgaata agtgattatt ctaaactatc acctcgtcga
    11881 ctataacaaa aaataaaaag agggtcaata agataattat ctcttcctaa atactcagaa
    11941 aagattctat aatttgtaca attgaacaag aaatgcttct ccaaaatcta tcttcaaaag
    12001 aatgttgcat ctttttatcc tttcacacaa acatttctct ttatacagat ccaagtgata
    12061 accagatgat aattggacac tttttggtta tttgtgtatt ttttgaaaaa ttttttaaaa
    12121 aaattttata tcctctttaa tagaagttta tgcatttgta tatatgtatt ccatcctatg
    12181 ttgtgtataa taacataaaa ttgtgctaaa tatcataatt tatattattt tccgagaaat
    12241 tatagccatt gacattacct aggaattgcg ttataacata catgtaagcg gtacccaaaa
    12301 tggtgccaag tcaaaatttt taaggaggaa aatacatgtc ttcacatcca attcaggtct
    12361 tctcagaaat tgggaaactg aaaaaagtta tgttgcaccg tccaggcaag gagttagaaa
    12421 acttgttgcc ggactatctt gaaaggcttc tttttgatga tattcctttc ttggaagatg
    12481 ctcaaaaaga acatgatgca tttgcccaag ctcttcgcga tgaaggaatt gaggttctct
    12541 acctagaaca actcgctgct gaatcattga cctctccaga aatccgcgat caatttatcg
    12601 aggaatactt agacgaagcc aacatccgtg atcgtcaaac caaggttgct attcgtgaat
    12661 tgcttcacgg catcaaggac aaccaagaat tggttgaaaa aacaatggct gggattcaaa
    12721 aagttgaatt gccagaaatt cctgacgaag ctaaagatct aactgactta gttgaatcag
    12781 attatccatt tgcaattgac ccgatgccaa acctctattt cactcgcgac ccatttgcaa
    12841 caattggaaa cgccgtatcg cttaaccaca tgtttgcaga cactcgtaac cgtgaaacac
    12901 tctacggtaa gtatatcttc aaataccacc caatctatgg cggaaaagtg gatttggtct
    12961 acaaccgtga agaagatacg cgtatcgaag gtggagacga gctagttctt tctaaagacg
    13021 tccttgcagt aggtatctct caacgtacag acgcagcttc tatcgaaaaa cttttggtca
    13081 acatcttcaa gaaaaatgtt ggcttcaaga aagttttggc ctttgaattt gctaacaacc
    13141 gtaaattcat gcacttggat actgtcttca ctatggtaga ctatgacaag ttcactattc
    13201 acccagaaat cgaaggcgac cttcacgttt actcagttac ttacgaaaac gaaaaactta
    13261 aaatcgttga agagaaaggt gacttagctg aacttcttgc tcaaaacctt ggtgtagaaa
    13321 aagttcattt gattcgttgc ggtggtggca atatcgtagc agctgcgcgt gaacaatgga
    13381 acgacggttc taacactttg accatcgcac ctggtgtggt agttgtttat gaccgcaata
    13441 ccgtgaccaa taagattttg gaagaatacg ggcttcgctt gattaagatt cgcggaagtg
    13501 aattggttcg gggccgtggt ggacctcgtt gtatgtctat gccatttgaa cgtgaagaag
    13561 tgtaatcgct gttcggtatt cgtcaataga aaatgtaaaa aatagaaaga ggaaataata
    13621 aaatgacaaa ttcagtattc caaggacgca gcttcttagc agaaaaagac tttacccgtg
    13681 cagagttaga ataccttatt ggtctttcag ctcacttgaa agatttgaaa aaacgcaata
    13741 ttcaacacca ctaccttgct ggcaagaata tcgctctcct atttgaaaaa acatctactc
    13801 gtactcgtgc agcctttaca actgcggcta tcgaccttgg tgctcaccca gaatacctcg
    13861 gagcaaatga tattcagttg ggtaaaaaag aatctactga agatactgct aaagtattgg
    13921 gacgtatgtt tgacgggatt gaattccgcg gattcagcca acgtatggtt gaagaattgg
    13981 cagaattctc aggcgttcca gtatggaacg gtctaactga cgaatggcac ccaactcaaa
    14041 tgctcgctga ctacttgact gttcaagaaa acttcggtcg cttggaaggc ttgacattgg
    14101 tatactgtgg tgatggacgt aacaacgttg ccaacagctt gctcgtaaca ggtgctatcc
    14161 ttggtgtcaa tgttcacatc ttctcaccaa aagaactctt cccagaaaaa gaaatcgttg
    14221 aattggcaga aggatttgct aaagaaagtg gcgcacatgt tctcatcact gaagatgctg
    14281 atgaagcagt taaagatgca gatgttcttt acacagacgt ttgggtatca atgggtgaag
    14341 aagacaaatt cgcagaacgt gtagctcttc ttaaacctta ccaagtcaat atggacttag
    14401 ttaaaaaagc aggcaatgaa aacttgatct tcctacactg cttgccagca ttccacgata
    14461 ctcacactgt ttatggtaaa gacgttgctg aaaaatttgg tgtagaagaa atggaagtaa
    14521 cagacgaagt cttccgcagc aagtacgctc gccacttcga tcaagcagaa aaccgtatgc
    14581 acactatcaa agctgttatg gctgcgacac ttggtaacct ttatattcct aaagtataat
    14641 tttagataat aaaccgtcta ccaacagcta tgagggctgc gactaatagc tttagtccgg
    14701 tcctctttta tgtaatggta atctattatt tcttataaaa tatgtgaaaa atcattaaat
    14761 tgaaatctaa acgcattcta ttgagtgtga taaaggagaa tttatggcaa atcgtaaaat
    14821 tgtagtagct ttgggaggaa atgcgattct ttcttctgac ccatcagcaa aggctcaaca
    14881 agaagcttta gttgaaacag ctaagcatct tgtaaaattg attaaaaatg gagatgatct
    14941 gattatcact cacggtaatg gacctcaagt tgggaatctc ttgctccaac atttggcatc
    15001 agactctgaa aagaaccctg ccttcccact cgactcactt gtcgctatga cagaaggtag
    15061 catcggtttc tggttgaaaa atgctttgca aaatgctctc ttggatgaag gcatcgaaaa
    15121 aaatgttgcc tctgttgtaa cgcaagttgt cgtagataaa aatgatccag cttttgttaa
    15181 cttgagtaaa ccaatcggtc ctttctattc agaagaagaa gcaaaagcag aagccgaaaa
    15241 aagcggagcg actttcaagg aagatgctgg ccgtggctgg cgtaaggtcg ttgcctcacc
    15301 aaaacctgtt gacatcaaag aaattgaaac catccgtact cttttaaata atggtcaagt
    15361 cgtcgtagct gcaggtggtg gcggtattcc cgtcgtcaaa gaaaacaatg gacatttgac
    15421 tggtgtcgaa gcggttattg ataaagactt cgcttcccaa cgtttggcag aattggttga
    15481 tgcagacctc ttcatcgttt tgacaggtgt agattatgta tttgttaact acaacaagcc
    15541 aaaccaggaa aaattggaac atgtgaatgt tgcccagctg gaagaatata tcaaacaaga
    15601 tcagtttgca ccaggtagca tgcttccaaa agtagaagca gctatcgctt ttgtcaatgg
    15661 tcgtccagaa ggaaaagcag ttattacttc ccttgaaaat ctaggcgcct tgattgaatc
    15721 tgaaagcgga acaattattg aaaaaggata agttgtttta ctaataagat gtattctatt
    15781 tctagtatct ttatatcaaa ttagaaatta ttcttgaaaa catgtacaat atttcaaaag
    15841 atattagttt tttagacttt aatatggtaa aacaaatata aatagaaagc gttttcttaa
    15901 atgtttattt aagaaagtag ttggtttttt acactttgtt agacatcagg aggaaaaaca
    15961 aatgagtgaa aaagctaaaa aagggtttaa gatgccttca tcttacaccg tattattgat
    16021 aatcattgct attatggcag tgctaacttg gtttatccct gcgggggcct ttatagaagg
    16081 tatttacgag actcagcctc aaaatccaca agggatttgg gatgtcctca tggcaccgat
    16141 tcgggctatg ctaggtactc atccagagga aggttcgctc attaaagaaa cgagcgcagc
    16201 gattgatgta gccttcttca tccttatggt tggggggttc cttggcattg tcaacaaaac
    16261 tggtgctctt gacgtaggga ttgcctctat cgtgaagaag tataagggcc gcgaaaaaat
    16321 gttaattttg gtactgatgc ctttgtttgc cctcggtggt acaacttatg gtatgggtga
    16381 agaaacaatg gccttctatc cactccttgt gccagttatg atggccgttg gttttgatag
    16441 cctgactggt gttgcaatta ttttgctcgg ttctcaaatc ggctgtttgg catctactct
    16501 gaatccattt gcgacaggta ttgcttcagc gactgcggga gttggtacag gggacggtat
    16561 cgtacttcgt ctgatcttct gggttacctt gactgctctt agtacttggt ttgtttaccg
    16621 ttatgcggat aagattcaaa aagatccgac taagtcactg gtttatagta ctcgcaaaga
    16681 agatttgaaa cactttaacg tagaagaatc ttcatctgta gaatctacac ttagcagcaa
    16741 acaaaaatca gttctcttct tatttgtgtt gacattcatc ttgatggtat tgagcttcat
    16801 tccatggaca gaccttggcg ttaccatttt tgatgacttt aatgcttggt tgactggtct
    16861 tccagttatt ggtaatattg tcggttcatc tacttctgca ctaggtactt ggtacttccc
    16921 agaaggcgca atgctctttg cctttatggg tatcctgatt ggtgttattt atggtcttaa
    16981 agaagataag attatctctt ccttcatgaa tggtgctgct gacttgctca gtgttgcctt
    17041 gatcgtagcg attgctcgtg gtattcaagt tatcatgaac gacggtatga ttaccgatac
    17101 aatcctcaac tggggtaaag aaggcttgag cggtctatct tcacaagtct ttatcgttgt
    17161 aacttatatc ttctatctac ctatgtcatt cttgatccca tcttcatctg gtcttgccag
    17221 cgcaactatg ggtatcatgg ctccacttgg agaatttgta aatgtccgtc ctagcttgat
    17281 tatcactgct taccaatctg cttcaggtgt cttgaacttg attgcaccaa catctggtat
    17341 tgtgatggga gctcttgcac ttggacgtat caacattggt acttggtgga aattcatggg
    17401 caaactcgta gtcgctatta ttgtagtgac catcgccctt cttctccttg gaaccttcct
    17461 tccattccta taaaatagtg agtgaggtga ttccatgaaa atagatataa caaatcaagt
    17521 taaagatgaa tttcttatat cattaaaaac cttgatttcc tatccttcag tactcaatga
    17581 aggagaaaat ggaacacctt ttggacaagc aatccaagat gtcctagaaa aaactttaga
    17641 gatttgtcga gacataggtt tcactaccta tcttgaccct aaaggttatt acggatatgc
    17701 agaaatcggt cagggagcag agcttctggc cattctctgt catttggatg ttgttccatc
    17761 aggtgatgaa gcagattggc agacaccgcc atttgaagca actatcaaag acggctgggt
    17821 attcggacgt ggtgtccaag atgataaagg cccttcgctc gcagctctct atgcagtaaa
    17881 aagcttgctg gaccaaggta ttcagttgaa aaagcgcgta cgctttatct ttggtaccga
    17941 tgaggaaacc ctctggcgct gcatggcacg ctacaatacc atcgaagaac aggccagtat
    18001 gggctttgca cctgactcat cttttcctct gacctatgct gaaaaagggc ttctacaggt
    18061 caaacttcat ggccctggat cggatcaact agagcttgaa gtaggaggcg cctttaacgt
    18121 tgtaccagac aaggccaact accaaggtcc cctctatgaa caggtttgta acgatctcaa
    18181 agaagctggt tatgattacc aatccactga acaaaccgta acggttctcg gagtgccaaa
    18241 gcatgctaag gatgctagtc aaggtatcaa tgctgtcatc cgactagcta ccattcttgc
    18301 tcctctccaa gaacaccctg ctctcagctt tcttgcaaca caagcaggtc aagacggcac
    18361 aggaagacaa atctttggtg atatagcaga tgaaccttct ggtcacctat cctttaatgt
    18421 cgcaggtctc atgatcaatc ataaacgttc tgaaatccgt attgacattc ggactcctgt
    18481 cttagctgac aaggaagaac tagtagagtt gcttacaaga tgtgcacaaa actaccaact
    18541 ccgctacgaa gagtttgact atctagcgcc tctatacgtc gcaaaagaca gtaaactcgt
    18601 tagcacactg atgcaaatct accaagaaaa gactggcgat aacagtcctg ctatttcatc
    18661 cggtggtgcc acttttgctc gcaccatgcc aaattgtgta gccttcggcg ccttattccc
    18721 aggagcgaag cagacagaac atcaggcaaa tgaatgtgcc gttctagaag atttgtaccg
    18781 tgctatggat atttatgccg aagccgtcta tcgacttgca acttaatcag gcaactgttt
    18841 ctacaaaaaa aaatcgaccg att
//
LOCUS       DAVHSY010000035        18137 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.036, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000035 DAVHSY010000000
VERSION     DAVHSY010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18137
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.036"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            357..1403
                     /gene="pheS"
                     /locus_tag="VVR43_001553"
     CDS             357..1403
                     /gene="pheS"
                     /locus_tag="VVR43_001553"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU6149898.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1403..1912
                     /locus_tag="VVR43_001554"
     CDS             1403..1912
                     /locus_tag="VVR43_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6149899.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GIGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1989..4394
                     /locus_tag="VVR43_001555"
     CDS             1989..4394
                     /locus_tag="VVR43_001555"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU6149900.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVESVESPAADLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENTVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIGTDK
                     APYYAARILDNVIIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPREELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQVSLEEKVNA
                     EVR"
     gene            complement(4462..5463)
                     /locus_tag="VVR43_001556"
     CDS             complement(4462..5463)
                     /locus_tag="VVR43_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU6149901.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVRDLDIVSFQNSDHRCIFTEITF"
     gene            5610..6016
                     /locus_tag="VVR43_001557"
                     /pseudo
     CDS             5610..6016
                     /locus_tag="VVR43_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6139..6405
                     /locus_tag="VVR43_001558"
     CDS             6139..6405
                     /locus_tag="VVR43_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6149902.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            6666..8915
                     /gene="metE"
                     /locus_tag="VVR43_001559"
     CDS             6666..8915
                     /gene="metE"
                     /locus_tag="VVR43_001559"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU6149903.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            8979..9845
                     /gene="metF"
                     /locus_tag="VVR43_001560"
     CDS             8979..9845
                     /gene="metF"
                     /locus_tag="VVR43_001560"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU6149904.1"
                     /translation="MSCQTPSLSFEVFPPNPAVGNDNIILALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIELIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNEHFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10530..12743
                     /gene="pnp"
                     /locus_tag="VVR43_001561"
     CDS             10530..12743
                     /gene="pnp"
                     /locus_tag="VVR43_001561"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU6149905.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12759..13376
                     /gene="cysE"
                     /locus_tag="VVR43_001562"
     CDS             12759..13376
                     /gene="cysE"
                     /locus_tag="VVR43_001562"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU6149906.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHSFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHAVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13388..14272
                     /locus_tag="VVR43_001563"
     CDS             13388..14272
                     /locus_tag="VVR43_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6149907.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14359..15702
                     /locus_tag="VVR43_001564"
     CDS             14359..15702
                     /locus_tag="VVR43_001564"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU6149908.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15695..16081
                     /locus_tag="VVR43_001565"
     CDS             15695..16081
                     /locus_tag="VVR43_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU6149909.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16085..16969
                     /locus_tag="VVR43_001566"
     CDS             16085..16969
                     /locus_tag="VVR43_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU6149910.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            17106..17705
                     /locus_tag="VVR43_001567"
     CDS             17106..17705
                     /locus_tag="VVR43_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149911.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGYNFSSVSSS
                     SQTAKYEGTGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEVTVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            17848..18018
                     /locus_tag="VVR43_001568"
                     /pseudo
     CDS             17848..18018
                     /locus_tag="VVR43_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         5459 a         3486 c         4102 g         5090 t
ORIGIN      
        1 attttacttt cccaatagat ttgttttcat cttatttcaa tccgctataa agttagataa
       61 gaataagcta acaagcagaa gtaagatagg tcttgcaaga atggtaaaaa tctgataaac
      121 taagtagtaa ttgaatagga atctgaaaga ctagtagccc aagggaagta tatcagggag
      181 gagagccgtg actgcaagct ctctatatga aagctgggtg aattcacttg cgcatggatt
      241 tagaaatgaa ggtctgactt gtcagatgaa aacggatggt accgcgtgtc aacgctccga
      301 gtggagtttt tggcatgtgg ttttcttttt atctacgaga gactgatgga ggaaatatgt
      361 caactattga agaacaatta aaagcgcttc gcgaagaaac gctggctagc ttgaagcaga
      421 ttactgctgg aaatgaaaaa gagatgcaag atttgcgtgt ctctgtcctt ggtaaaaagg
      481 gttcgctcac tgaaatcctc aaagggatga aagatgtttc tgctgagatg cgtccaatca
      541 tcgggaaaca cgtcaatgaa gctcgtgatg tcttgactgc tgcttttgaa gaaacagcta
      601 agctcttgga agaaaagaaa gtcgcggctc aactggctag cgagagtatc gatgtgacgc
      661 ttccaggtcg tccagttgcg actggtcacc gtcacgtttt gacacaaacc agtgaagaaa
      721 tcgaagatat cttcatcggt atgggttatc aagtcgtgga tggttttgaa gtagagcaag
      781 actactataa ctttgaacgt atgaaccttc caaaagacca cccagctcgt gatatgcagg
      841 atactttcta tatcactgaa gaaatcttgc tccgtaccca cacgtctcca gttcaggcgc
      901 gtgctatgga tgcccatgat ttttctaaag gtcctttgaa gatgatctcg ccagggcgtg
      961 tcttccgtcg cgatacggac gatgcgaccc acagtcacca attccaccaa atcgaaggct
     1021 tggtagttgg gaaaaatatc tctatggctg atcttcaagg aacgcttcag ttgattgtcc
     1081 aaaaaatgtt tggtgaagag cgtcaaattc gtttgcgtcc atcttacttc ccattcacag
     1141 agccatctgt tgaggtggat gtttcttgct tcaagtgtgg tggagaaggc tgtaacgtat
     1201 gtaagaaaac aggttggatc gaaattatgg gagccggtat ggttcaccca cgtgtccttg
     1261 aaatgagtgg tatcgatgcg actgtatact ctggttttgc ctttggtctt ggacaagagc
     1321 gtgtagctat gctccgttat ggaatcaacg atatccgtgg attctaccaa ggagatgtcc
     1381 gcttctcaga acagtttaaa taatgattag aaaagtagaa atggcagatg ttgaggtgtt
     1441 ggctaaaatt gccaaacaag cctttcgtga aacctttgcg tatgataata cggaagagca
     1501 gttacaggaa tactttgaag aggcttatag tctgaaaact ttgtcaactg agttgggaaa
     1561 tcctgactct gaaacctatt tcattatgca tgaggaggag atagctggtt ttctcaaagt
     1621 caactgggga agtgctcaaa ctgagagaga attagaggac gcttttgaaa ttcaacgcct
     1681 ctatgtgcta caaaaattcc aaggatttgg aataggtaag caactgtttg aattcgcact
     1741 tgaacttgct acaaaaaata gtttttcttg ggcttggcta ggtgtttggg agcataatac
     1801 aaaagctcaa gcgttttata atcgatatgg ttttgaaaaa tttagccaac atcattttat
     1861 ggttggtcaa aaagtagata cggattggtt actgagaaag aaattaaggt aagaagagga
     1921 ttcttctatt gaaatgatag gaaaggaaaa gaaccagtgt ggcaatggtc attctggaga
     1981 actaaattat gcttgtatct tataaatggt taaaagaatt ggtggacatt gatgtgccat
     2041 cacaggagtt ggctgaaaaa atgtcaacca cagggatcga ggtagagagt gtcgaatcac
     2101 cagctgctga tctctcaaaa attgttgtcg gtgaggtctt gtcttgcgaa gatgtgccag
     2161 agactcacct ccatgtttgt caggttaacg ttggcgaaga agaagcccgt cagatcgttt
     2221 gtggtgcccc aaatgtgcgt gctgggatca aggtcatggt ggctcttcca ggagctcgta
     2281 tcgctgataa ctacaaaatc aaaaaaggaa aaatccgtgg tttggagtca cttggaatga
     2341 tctgttcact tggtgaattg ggaatttctg actcagttgt gcctaaggaa ttcgcagatg
     2401 gcatccaaat cttgccagaa aataccgtgc caggtgagga agtcttttct tacctagact
     2461 tggatgatga aatcatcgaa ctttccatca caccaaaccg tgcagatgcc ctttctatgt
     2521 gtggagtggc tcacgaagtg gcagccatct atgacaaggc agtcaacttt aaagaattta
     2581 ctctaacaga aactaatgaa gctgcggcag atgccctttc tgtcagcatt gggacagaca
     2641 aggcgcctta ctatgcagct cgtatcttgg acaatgtgat tatcgcacca agtccacaat
     2701 ggttgcaaaa ccttctcatg aacgaaggca tccgtcccat caataacgtt gtagacgtga
     2761 caaactacat cctgctctac tttggtcaac ctatgcatgc ttttgacttg gacacatttg
     2821 aagggactga catccgtgtg cgtgaagcgc gtgctggtga aaaattggtg accttggacg
     2881 gtgaagaacg tgacttggac gtgaatgacc tagtcatcac tgttgcagac aagccagtag
     2941 cccttgcagg tgtcatgggt ggtcaagcaa cagaaatctc tgaaaaatct agtcgtgttg
     3001 tccttgaagc tgctgttttc aatggtaaat ctatccgtaa gacaagtggt cgcctgaacc
     3061 ttcgttcaga atcgtcttct cgctttgaaa aaggcatcaa tgtggcaaca gtcaatgaag
     3121 cccttgatgc ggcagctagc atgattgcag aacttgcagg tgcgacggtg cgtaagggta
     3181 tcgtttcagc gggtgagctt gatacctctg atgtggaagt ttcttcaacc cttgctgatg
     3241 ttaaccgtgt cctcggaact gagctgtctt atgctgatgt cgaagacgtc ttccgtcgtc
     3301 ttggttttgg tctttctgga aatgcagaca gctttacagt cagcgtacca cgtcgtcgtt
     3361 gggatatcac aatcgaagct gacctctttg aagaaatcgc tcgtatctat ggatatgacc
     3421 gcttgccaac tagtctacca aaagacgatg gtacagctgg tgaattgact gtgacacaaa
     3481 aactccgccg tcaagttcgt accattgctg aaggagcagg tttgacagaa atcatcacct
     3541 atgctctaac aactcctgaa aaagcagttg agtttacggc tcaaccaagt aaccttacgg
     3601 aactcatgtg gccaatgact gtggatcgtt cagtcctccg tcaaaatatg atttcaggta
     3661 tccttgatac cgttgcctac aacgtggctc gtaagaataa aaacttggcc ctttacgaga
     3721 ttggaaaagt ctttgaacaa acaggtaatc caagagaaga acttccaaat gaaattaaca
     3781 gttttgcctt tgccttgaca ggcttggttg ctgaaaaaga tttccaaaca gcagcagttc
     3841 cagttgattt cttctatgct aagggaatcc ttgaagccct atttactcgc ttgggactcc
     3901 aagtaaccta tacagcaaca tctgaaatcg ctagccttca tccaggtcgt acagcagtca
     3961 tttcactcgg tgaccaagtt cttggtttcc ttggccaagt gcatccagtc actgctaagg
     4021 cttatgatat tccagaaacg tatgtagctg agcttaacct ttcagctatc gaagctgcgc
     4081 ttcagccagc gactccattt gtagaaatca ccaaattccc ggcagtcagc cgtgacgttg
     4141 cccttctcct caaggcagaa gtgactcatc aagaagttgt agatgctatc caagctgccg
     4201 gcgtgaaacg tttgacagat atcaaactct ttgacgtctt ctcaggtgag aaattgggac
     4261 ttggtatgaa gtcaatggct tatagcttga ccttccaaaa tccagaagat agcttaacgg
     4321 acgaagaagt cgcacgctat atggaaaaaa tccaagtatc gctcgaagaa aaagtgaatg
     4381 cagaagtgcg ttaaacgata gtatgataca aattccccct ctagtttatg aacactagag
     4441 gggtgatttt atataaaata attaaaatgt gatttctgta aaaatacatc tatgatcaga
     4501 gttttgaaaa cttacaatgt ctaaatctct aacatagtag tggtttttag gcaataagat
     4561 atgatctatc gttgcattaa aaagttttgg actttggcta ttccaagttc ctctttcaaa
     4621 aggtggaagt gcattcaatg cgtccctatg agagcttatt tttgcaagtg ctccatgacg
     4681 catagttgca ttaaaatcac ctgcaataat agcctttgga tattttgaag ccaattgatt
     4741 atgaatgatg tttaagtctt gcttccagat ttccattaaa cctggcagag gaggagcagt
     4801 atgcaaggca atgatatctg gtatattttg ttttctcgaa tgtaatacaa ttgtcccgaa
     4861 ccgtgttgta tgaaaagttt tagcttctgt atagaaacca taacttttct tgacaatcac
     4921 agtcacagga gctattccac tattggtagg tggagaagtg aaaatatcat agttggccat
     4981 agaaagtcca acttgatgaa acaatagttt gattctctgg ttttcttgct cacctctgat
     5041 attggtagct agttcaggga atatagccat atcggcatca aaatggctaa aaattcgctc
     5101 aatatgttgt gcttctattt gattagcgac gttccaagtt actaatttta aggttttagt
     5161 cttatttgat gcagaagaaa gggttttatc tgttccgaat aatagtaata tgagcgatag
     5221 taagagcaaa atgccagagt aaaaccgtat ttgtttattt ttcttgtaaa aagataggga
     5281 aaaaaatacg aaacttaaaa tagaagccat agttgcagta gctaagggga aggcataaat
     5341 ctgtgccaag ataggtctgg tagatagcca aatattaaga ttagaagatg gaaaaaaaga
     5401 ataagctatg atagggataa caaagagaat gaccgaaagg gcagagagaa atgttttaat
     5461 cattgtgtga gtacctcaat ttgcaatggt tgctcggagc taatgtgact ttacttgatt
     5521 gatattcttt ttcttgtctt cctcatagat taagtacaac ccaagtaaaa aagttcaatt
     5581 taagattgaa atgattaaaa ggcacagaaa tgcaagacaa ttatactaca aaaggcaaac
     5641 atttgacaat cgatagccgt cgcttaatcg aacgatggaa aaaagaagga aaatcaaata
     5701 gagaaattgc ctctctactt ggaaaagctc ctcaaactat ccacactgaa atcaagcgtg
     5761 ggacagtccg acaatgtctt ggaaaagggc gcttcaaaga gatttattct gccgactacg
     5821 ctcaacagtc ttaagaaact aaaggaaaag attctccact atacataacc aaaaattttc
     5881 gcctgaaatg atggtgatgg ctaaaggggt taacgtggga atttcaacca tttactattg
     5941 aattcatcgt ggaaaattgg ggttaagcaa gcaggatctg ctttatccta gaaaaggaaa
     6001 atcgcttaag aaataggcta gcaccaactt taaacccgct ggtcaatcta tcgaatcata
     6061 attcgctcat ttttttaaaa atacatagac gtaaaaaaaa gagggttaag tgatgaagaa
     6121 tagtgctatt gggagtaatt ggaaggatgt ccatctgagc tctttagcaa ggaggaaatc
     6181 cttgaaagtg atatgcgagt ggctatcatg agcgagttga ttgaggctag gtatgaacaa
     6241 ggaatcagtc agaaaaagct ggaagaagtc agtggaataa gccagcctgt catagctagg
     6301 atggagacag gagagagcag tcttcagttg gatacggtct taaaagttct aaccagtcta
     6361 ggaaagacac tagcagtcgt tccacttgaa caggggaaaa gttgactaga atcagttata
     6421 gtcttttcta ataacaggtc atagtcactt ataagaatta ctaataacat gttttagtat
     6481 tctaattgga atatagctgt aaagtaagaa ttacaaagga tttgagatgt ttgcttcaag
     6541 tctttttctt ttgtccgaaa cagatatata gtttcaaact atatcaaacc ctaatttttt
     6601 acaattatac agacgctttc ttttctgtta agatagtttc aacaacaaat tttggaggac
     6661 acatcatgtc aactacaatc atcggtttcc ctcgtttggg cgaattccgt gaattaaaat
     6721 ttacaactga aaaatacttt agaaaagaaa tctcagaaga agaactttta gcagcagcaa
     6781 aagacttgcg tgctaaacac tggaacattg tcaaagaaaa aggcatcact gaaattccat
     6841 caaatgactt ttctcactat gataacttcc tagatgcggc tttccttttc aacgtggtgc
     6901 ctgcatccgt tcaaaacttg gacttgtctg accttgagcg ctacttcgct ttgggacgtg
     6961 gttaccaggg agaaaaaggg gacgttcgcg cccttccaat gaagaaatgg ttcaacacta
     7021 actaccacta catcgttcct aaatttgaaa aagacactca agtaaaattg gctggtcaca
     7081 agattttcga tgagttccaa gaagcaaaag aacttggatt gaacactcgt cctgttcttg
     7141 taggtccctt cactttcctt caattgtcag actttgaaga aggcgtgaaa gcagacgact
     7201 tcgtagatag cttagtagtt gcttaccaag aagtttttgc taaattggct gaacttggtg
     7261 cgactcgcat ccaattggat gaagcggctc ttgtaaaaga cttgacagct gaagaaaaag
     7321 ctctcttctt gaacctttac aacaaactct tggctgacaa aaaaggtctt gaagtcttgc
     7381 ttcaaactta tttcggtgat gttcgtgacg tatacgctga ccttgtaaac ttaccagtag
     7441 atgctatcgg tcttgacttt gttgaaggta agaaaactct tgaactcgtt aaaggtggct
     7501 tcccagctga caagactctc tatgcaggta ttgtcaatgg taaaaacatc tggcgtaaca
     7561 actacgaaaa gagcttggct gttcttgagc aaatcccagc tgaaaacatc gttttgacaa
     7621 gctcttgctc acttcttcat gtgccattta caactgctaa tgaagaattt gaaccagcac
     7681 tcttgaacca ctttgccttt gcagttgaaa aattggatga aatccgtgac ttggatgcta
     7741 tccgcaatgg tcaaggttca gaagctcttg cagccaacaa agaactcttt gcgactgagc
     7801 gtgttggtga aaatgctgaa cttcgtgcgc gtatcgctgg cttgacagac gcagactaca
     7861 ctcgtttgcc agcctttgca gaacgtgaag ctatccaaga agaagctttt aaacttccag
     7921 ctcttccaac aacaacgatt ggttcattcc ctcaaacaaa agaagttcgt gccaaacgtt
     7981 tggcttaccg taaaggtgaa ttgtctcaaa aagagtacga cgctttcctt gctgaaacga
     8041 ttgacgaatg gatcaagtgg caagaagata ttgactttga tgtccttgtt cacggtgaat
     8101 ttgagcgtaa tgacatggtt gagtacttcg gtcaaaactt gtcaggatac ctcttctcta
     8161 aaaatggatg ggtacaatca tacggtatgc gtggggtaaa accaccaatc atctggggtg
     8221 atgtcactcg tcttaaccct atcactgtta aatggtctag ctatgcacaa agtcgtacaa
     8281 acaaacctgt taaaggtatg ttgactggac ctgttaccat cctcaactgg tcattcccac
     8341 gtgaagacat ctctatcaag gattctactc ttcaaatcgc ccttgctatc aaggatgaag
     8401 tgcttgacct tgaagctgct ggtgtgaaaa tcatccaaat tgatgaggct gctcttcgtg
     8461 aaaaattgcc actccgtcgt agtgactggt acgaagatta ccttgactgg gcaattcctg
     8521 ccttccgctt ggtacactca acagtagcgt cagacacaca aatccacact cacatgtgtt
     8581 actcagaatt tacagatatc atcccagcta tcgataacat ggatgcagac gttatttcct
     8641 ttgaagccag ccgttcaaac cttgaaatct tggacgaact caaagcgaaa aacttccaaa
     8701 cagaagtggg acctggggtt tacgatatcc actcacctcg tgtaccaaat gaaggcgaaa
     8761 tcgacaacac aatcgaagcc atccttgcta aagtgccaag caagaaagtt tggatcaacc
     8821 ctgactgtgg tttgaaaaca cgtggtatcc cagaaacaaa agaaagcttg atccgccttg
     8881 ttgaagcagc taaagctgcg cgtgagaaat tgtaagattg gatttctctc catacagtgg
     8941 ttgttcaaaa agaaatcaac tagaaaaggt tattacatat gtcatgccaa acaccgtcac
     9001 tctcatttga agtgttccct ccaaacccag ccgtgggtaa tgataacatt attttagcct
     9061 tgcaggatat gcaggagttg gctccccatt ttatcagtgt aactgccagc aataataaat
     9121 ttaatatcaa ggaaacgacg gttcgtttgg ctgactttat ccaaaatgac ttggcgattc
     9181 cgaccattgc ccacttgcca gctatttatc taactaagga caaggttgct gaaactattg
     9241 ctgacttgga caaagttggg gtgcagaaaa tcttggctct tcgtggggat attattccag
     9301 acgtggaacc acaaaaggat ttccgctatg caaccgactt gattgagctt atcaaggaac
     9361 aagcccctca ctttgatatt attggagctt gctatccaga agggcatcca gattcgccaa
     9421 atcagatttc agatattcaa aatcttaaga agaaagtgga tgcaggctgt tcgagcctcg
     9481 taactcagct cttctttgac aatgagcact tctatgattt tcaggacaag tgcatcttgg
     9541 ctgggattga tgttcccatt catgcaggaa ttatgccaat tctgaatcga aatcaggctc
     9601 tccgactctt gaagacttgt gagaatatcc atcttccacg caaatttaaa gccatcttag
     9661 acaagtatga gcatgaccct gagtcgctca gagcagcagg acttgcctat gcagtggacc
     9721 aaatcgtaga cttggtaact caggatgttg ccggtgtgca tctctatacg atgaataatg
     9781 ctgatacagc aaaatacatc catcaagcaa cccatgcctt gtttaatcac cagtctctag
     9841 gataataaaa gcaaaccatt cttctcaggt gaggggaatg gttccttttt aatggtaaag
     9901 acctcacttt ttaagaaaaa tatgataaaa taaattctgt acgtacttga tacaaagatg
     9961 aaggtattaa ataatacaat gcatttaaac tgtaagattt aacgacacga gtgagtcaaa
    10021 tcgatgttat ttgacgagag agttagtaaa gcatttagct aatcgcccga tagcgattag
    10081 cgtgaaagct ttagatactt tagtattaaa cctttctaat gatgtatctt gaaaactgaa
    10141 cttgcctaca actctgtgga aaaagataaa tctccctagg agcagtcgct ccgtcgttcg
    10201 atttcctatc ttcctttgag ttgcttgacg gcttggtatc ttgatgactt gaattttggt
    10261 ctcatttctt aggaaaaaag ataagcttcc tagcactcgt cgagtgcgaa gtcaccttcc
    10321 tatttttcta cagaaatgtt cggcaagccg aaccgtccaa aatatcttgt gtaattgaac
    10381 acggccgaaa agctgtgtaa aaaagataaa ctgtcttgtc ttcatcgaag acttcgtcag
    10441 tttcctattt ttactttgct tttgacgtcc ttggtatctt gatctttgta ggcaaggcgt
    10501 ataatttcat caatccaaag gggattaaaa tggcaaaaca agtgtttcaa acgacttttg
    10561 cgggtcgtga gttaattgta gagactggtc aggttgctaa gcaagcaaat ggatctgttg
    10621 tcgtacgtta cggtgagtca actgtcttga ctgctgccgt tatgtctaag aaaatggcaa
    10681 ctggggattt cttcccactc caagtcaact acgaagaaaa aatgtatgcg gctgggaagt
    10741 ttcctggtgg ctttatgaaa cgtgaaggac gtccttcaac agatgcgacc ttgacagcgc
    10801 gtttgattga ccgtccgatt cgtcctatgt ttgcggaagg tttccgtaat gaagtccaag
    10861 tcatcaatac agtgctttct tatgatgaaa atgcatctgc accaatggct gctatgtttg
    10921 gttcatcttt ggcactgtct atttcagata ttccatttga cggaccaatt gctggggtac
    10981 aagtgggata tgtagatggc caaatcatca tcaacccaag tcaagaacaa gcagagcaat
    11041 ctcttcttga attgacagta gctggaacca agcacgctat caacatggta gagtctggtg
    11101 ccaaagaatt gtcagaagaa atcatgttgg aagcgcttct taaagggcac gaagctgtca
    11161 aagaattgat tgccttccaa gaagaaatcg ttgctgctgt cggtaaagaa aaagcagaag
    11221 tggaattgct tcacgtggat gctgaattgc aagctgaaat cattgcagcc tacaacagtg
    11281 acctccaaaa ggcagttcaa gtagaagaga aattggcccg tgaagctgca actcaagcag
    11341 tgaaagacca agtgactgcc gtttacgaag aaaaatatgc ggaccacgaa gaatttgacc
    11401 gtattatgcg tgatgtggct gaaatcttgg aacaaatgga acacgcagaa gtgcgacgtt
    11461 taattacaga agacaaggtg cgtcctgatg gtcgtaaggt cgatgaaatc cgtcctttgg
    11521 atgcggttgt tgacttcctt cctcgtgtac atggttcagg tctctttact cgtgggcaaa
    11581 ctcaagctct ttcagtcttg accttggctc cgatgggaga aactcaaatc attgatggtt
    11641 tggatccaga gtacaagaaa cgctttatgc accactataa cttccctcaa tattctgtag
    11701 gggaaacagg tcgttacggt gcgccaggtc gtcgtgaaat cggtcacggt gctcttggtg
    11761 agcgtgctct tgctcaagtc ttgccaagct tggaagaatt cccatacgct atccgtctag
    11821 tagcagaagt tttggaatca aacggttctt catctcaagc ttctatctgt gcgggaactc
    11881 ttgcccttat ggctggtggt gtgccaatca aggcgccagt agctggtatt gctatgggac
    11941 ttatctcaga tggaaataac tacacagtat tgacagatat ccaaggtttg gaagatcact
    12001 ttggagatat ggacttcaag gttgcaggta ctcgtgatgg gattacagcc cttcaaatgg
    12061 atatcaagat tcaagggatt actgcagaaa tcttgacgga ggctcttgct caagccaaga
    12121 aagcgcgttt tgaaatcctt gatgtcattg aagcaaccat tccagaagtt cgtccagaat
    12181 tggctccaac tgctccgaaa attgatacga tcaagattga tgtggacaag attaagattg
    12241 tcatcggtaa gggtggagaa accatcgaca agattattgc tgaaacaggt gttaagattg
    12301 atatagacga agaaggaaat gtgtctatct actctagtga ccaagatgct attaaccgtg
    12361 ccaaagaaat tattgctggt ttggttcgtg aagccaaagt ggatgaagtt taccgtgcta
    12421 aagtcgttcg tatcgagaaa tttggtgcct ttgttaacct ctttgataag acagatgccc
    12481 ttgttcatat ctctgagatg gcttggactc gtaccaatcg tgtagaggat ttggtagaaa
    12541 tcggggatga agttgatgtt aaggttatca agattgatga aaaaggccgt atcgatgctt
    12601 ctatgaaggc tcttctacct cgtccgccaa aacctgagca tgatgaaaaa ggtgaaaagt
    12661 ctgagcgccc tcaccgccca cgtcatcaca aggatcacaa acctaagaaa gaatttacag
    12721 aaacaccaaa agattcagaa taagaaaagg agaaatgtat ggggtggtgg cgcgaaacca
    12781 ttgatatcgt aaaagaaaat gatccagcgg cccgcaccac tttggaggtt ttgctgactt
    12841 atccaggtgt caaggccttg gcggcccacc gtctctcgca ttttctctgg aagcacagct
    12901 tcaaactctt agctcgtatg cacagtcagt tttggcgctt ttggactcag attgagattc
    12961 atccaggagc ccagattgat tcaggtgtct ttattgacca tggttctggt ctggtgattg
    13021 gagagacagc gattgttgaa aaaggcgttc ttctctatca cggagtgact cttgggggaa
    13081 cagggaaaga ctgtggcaaa cgccatccga ctgtacgaaa gggagccctc atatcagccc
    13141 atgcccaagt tatcggacct gtggaaattg gtgaaaatgc caaggtcggt gctgcagcag
    13201 ttgtcgtagc agatgtacct agtgatgtga cggttgtcgg tattccggcc aagattgtcc
    13261 gtcttcatgg taagaaagat gagcctgtta ttcacgcagt cgaagaaaaa cgagagtatt
    13321 atgtcaataa actcgagcag gctaaagatg ccagtcacag atcgtctggt ttgtagagga
    13381 tacctatatg attcaagcaa gaaacaagtt aagccaagag gagctatctg aggcgaaaaa
    13441 agtaattaac tgttgccaaa actatgacgg tacctatcgc gatccctatc tctctaacat
    13501 gcttaatttt gacccaaaca tgcccgcctt tttcctttat tatgaaaaag gcaaacttgt
    13561 tggtttatta actgtctatg cagatgacca agatgtagaa gtgacgatac tggttcatcc
    13621 aggtcatcgc cgtcagggga ttgcgcgtgc attgtttact agttttgaga gagaaacagc
    13681 ttctttccct attcggtcag tcacttttca gacagaacgt atttttttag agaatcatcc
    13741 tgactttgcc agtaactggg gactaatcga ggatgaagag acagaaactt ggttaggtaa
    13801 ggatagaaga ccttatccgt tagcaaatgt ttcccatctt gaaattttgt tagcagatag
    13861 ttcgtatcag gatcaaatta gtcaattaaa atttcaggca ttttcagagg aacatgaatc
    13921 gagagaagtt gtggatagat atgtcgctga agctctgaaa gatccagaaa gccgactata
    13981 tattttatta aaagctggtc aggttattgg gacttgcacg gttgatttat cgagcgatac
    14041 gaattacttc tacggtttag caatatcaga acctgaacgt gggaaaggct atggaagcta
    14101 cttagcaaaa tcccttgtca accaactaat tgagcaaaat gataaggaat ttcagattgc
    14161 agtggaagat agcaatgtag gtgccaaacg tttgtatgaa aaaattggct ttgtcaaaca
    14221 gacacaggtg gtttatctga atgagaaagg agcaagggat tccgaagtgt agagacattc
    14281 ggactgaaat ttacttgagc tcttagttta gtgatgaaac taacagttct tggattttag
    14341 ctttcctgat tatgatttat gattaaaatc tatgacacca tgtctcgtga tttgcgagaa
    14401 tttgtcccga ttgaggacgg caagatcaag atgtatgttt gtgggccaac ggtgtacaac
    14461 tatatccacg tgggaaacgc ccgttcgacg gtagcttttg atacgattcg tcgctatttt
    14521 gagtaccgtg ggtataaggt tgcctatatt tccaatttta cagatgtgga tgataagatt
    14581 atcaaccgtg ccagggaaga aggcatcacg cctcaggagg ttgcggataa gtacatcgct
    14641 gcctttcgtg aggatgtgac ggccttgggc gtgaaacctg cgactcgcca tccgcgtgta
    14701 gtggagttta tggcagacat catccgtttt gtggaagact tgatcgagaa aggctttgcc
    14761 tatgagagtc aaggggatgt ctatttccgt gtagaaaaat cccacaacta tgctaaattg
    14821 gctaataaaa ccttggaaga tttggagcta ggtgcttcag gtcgtaccga tgaagaaacg
    14881 gctcgtaagg aaaatcctgt agactttgct ctatggaaat cttccaaacc aggtgagatt
    14941 tcttgggata gtccttgggg acctggacgt ccgggttggc atattgagtg ttcagtcatg
    15001 tcgacagaga ttttaggtga taccattgat atccacggtg gtggagctga cctagagttt
    15061 ccacaccaca ccaatgaaat tgcccaatct gaagctaaaa caggcaaggc ttttgctaac
    15121 tactggatgc acaatggctt tgtcaatatc gacaatgtca aaatgtctaa gtccttgggt
    15181 aacttcatta cggtacacga tgcccttaaa actcttgatg ggcaagtact tcgtttcttc
    15241 tttgcgaccc agcactaccg taagcctatc aacttcacgg aaaaggcagt tcgcgatgcc
    15301 gagaccaatc tcaagtatct gaagaatact tacgaacaac catttacagg aaacgtggat
    15361 gcccaagagt tacaaaactt taaagataag tttgtagcag ctatggatga agattttaat
    15421 gctgccaacg gtatcacagt tgtctttgaa atggccaaat ggatcaactc agggaactat
    15481 gatgcaagtg tcaagcaagc tcttgcagat atgttagaaa tttttggaat tgtctttgtt
    15541 gaggaagttt tggatgcaga gattgaagac ttgattcaaa aacgccaaga ggcgcgtgcc
    15601 aatcgtgact ttgcgacagc agaccaaatc cgtgaccaat tggttactca aggaattaag
    15661 ctccttgata ccaaggatgg agtgaggtgg acacgtgatt gatgtcaatc tcattaacgg
    15721 gattgcgcta gcctttgagg gggatgcggt gtattctatg tatattcgcc gtcacctcat
    15781 cctcaaaggt atgaccaaac ccaataaact ccatcaagaa gcaaccaagt atgtgtcagc
    15841 caaggctcag gctcgcctga ttgctctcat gttggaggag caggtcctaa cggaaaaaga
    15901 agaagaaatc tacaaacgtg gccgcaatac caatagccac acaaaggcta aaaatgcaga
    15961 tgtcgtgact tatcgtatgt ccacgggatt tgaagcggtt atgggctatc tccatatgac
    16021 tgagaatctg gaacgtcttg agagtttggt ttcatggtgc atccaaaaag tggagggcta
    16081 gaacatgagg gaaaaagaac tacaagactg gtttcctgag gctcggattt cagaccaacc
    16141 agtagagaaa gagggctatc tcacgctccc tttagcttct cagcagtgga ttttgctgga
    16201 ggaagctggg ctcagcgagc gtgaaaagca gttggttgcc cttttgaccc agcaggagca
    16261 ggctcgttcg ctaaaccctt ggtattccta tctggttgaa ggcaagggac aggcaccgca
    16321 agtttttaaa aagattcagt tggtttattg ccatctttct tattttcagc aggaaaatct
    16381 gacttcttgg ctagatatga tgcggactct ttttccgaat tgtcagacag tgctacaggt
    16441 cggagctcag gattatgttt tcgtgcttca acaagacaaa tacacttctg taagagatat
    16501 tttaagtgat acgattgaag cggttgagta tgattttgga cttcgtcttt ctatcatgtt
    16561 gggtcaggtt tggtctcaga caggacatca agccctatca gacttaatca aagctgagcg
    16621 ggatttgttc aagacatggt ggcgtcaggg tcaccaaggt gttcatactt tttctcagct
    16681 ctatctttgg agtatgggag aaagactcgt ggacttgaag ccaattaaag aatgtctaca
    16741 ccagatgatt ttggatcaag atcagattca ggaaatcatt ctctctcttt gggaaaatag
    16801 tgctgttctc actaaaacag cccagcaact ctatctgcac cgcaattctc tccaatacaa
    16861 gattgataaa tgggaagagt tgacagggct tcagttgaaa gagttgaccg acctgacctt
    16921 gtgttatcaa ttgattttag gttctttgtc aactatagtt ggtttgtaaa gaagttaata
    16981 tttggagaag aggattgcca tcttctccat ttttatgtgc agagttatag tggcttgatg
    17041 ctgggaaagt acactgtgac tgctaaaaca ttcctagaag ctgctttgat ttccctaatc
    17101 tatttatgca aattttatgt tattttacta taacagttgt tgctaagcca aataatagtg
    17161 gggaagttca tttagacgta agcattgaag ataatcaggg aggtagtggg tataatttca
    17221 gttctgtttc aagtagctca caaacagcta aatatgaagg aactggttat aataacaatt
    17281 catcattata tataacgatt gataaaacgt ctgatgcaac agctcttttg aaattaaagt
    17341 tgaataatgt tgataatcaa cctgctactg aagttcctag ttcaggaatt actgtaaaat
    17401 taaatgctaa agataatgct ggaaactgga caagtgcttc gaataaaaaa gaagtaacag
    17461 taaaaattgt ttctgctaaa ccgacatatc cagacaaaat cttagtgaaa aatcctgata
    17521 atataaaaga tacagaaaaa aatgccatta ttgaaaaatt gaaagaggca aataaaaatc
    17581 atccagcagg agctccaacc tttgctaaag gtgaaggaga gcatgcaaat gatattgtag
    17641 caacttattc agatggtaca acttattatg taccgttaaa tgatgtgaca aaatatgcga
    17701 ggtagtggct gtaccactca cttattcacc tccccgtgat ttgtagtagt gataggcttt
    17761 ctcactatta ttataaaaca aaataaagat cacaacactt tttcattctg tgttgtgcct
    17821 tgagtgaaac gaaaggaatg aattataaat atgaaaagta tagtcactag catagatgag
    17881 cgcttgcgta ctcgcctacg agtgattatc tggaagcaat ggaagaagaa atcgagacga
    17941 ttatggggat tgcttaagtt aggggttcct aaatggatag cagataaggt atctggctgg
    18001 ggcgaccact atcaattata ttaaaatgaa ataagaatag gacgaatcaa tcagggaagt
    18061 caaatcgatt tctaacaata ttttagaagt agaggtgtac tattctagtt tcaatctact
    18121 atagtagctc agaagtc
//
LOCUS       DAVHSY010000036        18112 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.037, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000036 DAVHSY010000000
VERSION     DAVHSY010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18112
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.037"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            16..86
                     /locus_tag="VVR43_001569"
     tRNA            16..86
                     /locus_tag="VVR43_001569"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48..50,aa:Gly,seq:tcc)
     gene            122..195
                     /locus_tag="VVR43_001570"
     tRNA            122..195
                     /locus_tag="VVR43_001570"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:156..158,aa:Ile,seq:gat)
     gene            202..289
                     /locus_tag="VVR43_001571"
     tRNA            202..289
                     /locus_tag="VVR43_001571"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:236..238,aa:Ser,seq:gct)
     gene            complement(415..1350)
                     /locus_tag="VVR43_001572"
     CDS             complement(415..1350)
                     /locus_tag="VVR43_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU6149912.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLIQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1347..2207)
                     /locus_tag="VVR43_001573"
     CDS             complement(1347..2207)
                     /locus_tag="VVR43_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU6149913.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKKGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2315..4477
                     /locus_tag="VVR43_001574"
     CDS             2315..4477
                     /locus_tag="VVR43_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU6149914.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4569..5828
                     /locus_tag="VVR43_001575"
     CDS             4569..5828
                     /locus_tag="VVR43_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU6149915.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5842..6708
                     /locus_tag="VVR43_001576"
     CDS             5842..6708
                     /locus_tag="VVR43_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6149916.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6722..7555
                     /locus_tag="VVR43_001577"
     CDS             6722..7555
                     /locus_tag="VVR43_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6149917.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7556..7636
                     /locus_tag="VVR43_001578"
                     /pseudo
     CDS             7556..7636
                     /locus_tag="VVR43_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7913..9355
                     /gene="gtfA"
                     /locus_tag="VVR43_001579"
     CDS             7913..9355
                     /gene="gtfA"
                     /locus_tag="VVR43_001579"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEU6149918.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSVFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNHSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            9493..10686
                     /locus_tag="VVR43_001580"
     CDS             9493..10686
                     /locus_tag="VVR43_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU6149919.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11372..13351
                     /locus_tag="VVR43_001581"
     CDS             11372..13351
                     /locus_tag="VVR43_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6149920.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13418..14914
                     /locus_tag="VVR43_001582"
     CDS             13418..14914
                     /locus_tag="VVR43_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6149921.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14914..15840
                     /locus_tag="VVR43_001583"
     CDS             14914..15840
                     /locus_tag="VVR43_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6149922.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINVVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15849..16916
                     /locus_tag="VVR43_001584"
     CDS             15849..16916
                     /locus_tag="VVR43_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149923.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16927..17853
                     /locus_tag="VVR43_001585"
     CDS             16927..17853
                     /locus_tag="VVR43_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149924.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(17928..>18112)
                     /locus_tag="VVR43_001586"
     CDS             complement(17928..>18112)
                     /locus_tag="VVR43_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6149925.1"
                     /translation="KIINALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFI
                     ALNIKKERTKFVLSRA"
BASE COUNT         5304 a         3222 c         3824 g         5762 t
ORIGIN      
        1 attgatagta tttatgcggg tgtagtttag tggtaaaact acagccttcc aagctgttgt
       61 cgcgagttcg attctcgtca cccgctttga actttgttca aattaccaag ttttttaact
      121 tgggcgcgta gctcaggtgg ttagagcgca cgcctgataa gcgtgaggtc ggtggttcga
      181 gtccactcgt gcccattaat tggagaatta ctcaagaggc tgaagaggac ggtttgctaa
      241 atcgttaggt cgggtaactg gcgcaagggt tcgaatccct tattctccgt tttaatgaga
      301 gtttgtaact ctcttttttg tttttagaga caataaaact tcagatccgt aaaacttaat
      361 tgaattacta atctgaagtt atttttatat cgtttatatt ataattgtgt tattttactt
      421 ccaactattg agagaaattt cgccactatt tagccagatt tcttttccgt tatcacattg
      481 aattaaaagt tttccatttt ctgagatgtc tttagcaagt cccttgtagt ctttttgctc
      541 tagtgtgaaa gtgacttctt ttcctagaat gaatgactgt tttttgtata ggtataatag
      601 ctcttctgct ggtgtttcga agaaagcacg ccagatttct atgatcaatt cattccttgt
      661 tataggagct gtagctttaa ataagctggc agctttttct tttaattcct gagggaagtc
      721 tttaatagtg aaattgatac ctactccaat aatgatatct gtgactaagc cagtttctac
      781 agaggtcatt gcttcagtaa ggattcctcc aattttatga ttgtttagat agatatcatt
      841 gacccatttt atgtcgacat ctattaaagt taggttctta atagctttgt agacagctcc
      901 agctacaagt agtgtgtagg atggtaattt gtcatagggg agatttggtt taagatggag
      961 tgtcatataa ataccacctt gtggtgagta gaaggaacgt tgaaaacggc ctcggcctgc
     1021 tgtttgatag gaagctagat agagggtatt tgcttcatgg cctaaatcaa ttgcttcttt
     1081 tgcatctagt tgtgttgatt ttgtttcggg tttaaagctg actttaattg gaagattttc
     1141 ttctagaatc tctggaagaa taaggtcacc attcatcagt ttatatcctc tatttttgat
     1201 actatcaatt tcaatgcctt cttgttctag tcgcttgatg gctttccaaa ttgctgttcg
     1261 gcttagggat agtttttctg cgattttttc tccgctgata tagtcggttt ctttagatag
     1321 gatttggtag acagcttggt aggatttcat aatgttgcct ttcttactag ttggtattga
     1381 gagtattctt ttcttgtatg acttggagtc tgattaaagt attgtttata agctttcgaa
     1441 aaatggagtg gatctgaaaa acctaccgag tatgcaatta ccttgatgga ctcttgggta
     1501 ttttcgagaa gttgtctagc tcggtgcatt cgaacgtaga gtaggtattc tttgggtgat
     1561 aaggtattaa attctttgaa tacgcttgat aagtagcttc tgtgaacgga tagttctttt
     1621 gctaaatctt gaattgtaag tgattgagga tagtggctat caattaatcg tttgcattca
     1681 agatagagtt ggtgggttga tgaaatattc ttttttttct gattgggagc aatagttccc
     1741 agatgaaaca tcagttcatg aagttgtccc atgatatgga gttgagctaa ttcacttgat
     1801 tttgtaatct gagcgaagcg gacaatgtct gagatgagtt ttgcagtagt ctgggtatga
     1861 caagtttcag attggatgag ataggattga tcagaaattt gagaaagagc aaaataatca
     1921 ggggatttcc ctccagtgat tcctaaccag tagtaggccc aaggttcttt actatctgct
     1981 tgataaaagg ttagttcctc tggttttaat agaaagaaat ctcctttttt taaatcaaca
     2041 attttaccct tgtaataaaa ttttccttgt cctttagtaa tgtaatgtag aacgtatgta
     2101 tcacgaatgg ctggaccaaa agagtaatta ggtgtgcatt cctcatatcc ataaaagctt
     2161 agggcaaggt cgattgttcc agtctggtat tctgaaaaaa ctaacatgtg ctacctccta
     2221 cctaacattt taccatattc ttgagacatt tttctatttc ggaaagcgat ttcaggtgat
     2281 aaaatataat caataaagtg atgaggtgaa gtaaatggga gttaggatag agaataatct
     2341 attttatgtt gagagtaaaa atctaagttt gattattgaa aatcgaaatg gctacttact
     2401 tttgaaacat ttaggaaaga ctattaagaa ctataaaggt tccaatagtg tttatgaacg
     2461 agaccatgcc ttttcaggaa atccaacggc tactaatcga acctttagtt tagatactca
     2521 gcgacagatt tttggacaac atggcttagg agattttagg aaaccaacca tacaggttca
     2581 gcatagtgta actgaagtaa cagactttcg atttgtagaa gcaaagattt taaaaggtca
     2641 gaatggtcca cagggcttac cttctccaca tagcatggac gatacagaga ctcttgtctt
     2701 aatgttagaa gattctaagg ctcaacttag tctgactttg tattatacta cttttaataa
     2761 tgatgcgact attgctagct acagtaaatt agataataat agtaatcagg aagttgtcat
     2821 ccataaagat ttttctttta tggctgattt tccagctgca gattacgaaa tagtaactct
     2881 gcagggtgct tatgctcgtg aaaagactgt tagacgtcaa caggtagaac aaggaatctt
     2941 ttcgattagc tcaaaccgag gtgcttctgg tcatgctcaa acaccagctc ttctactatg
     3001 cgaacaagga gtcacagagg atgctgggaa tgtgtttgct attcaactaa tgtatagtgg
     3061 caactttgaa gcttttgttc aaaaaaatca attgaatgaa gttcgggtgg ctattggcat
     3121 taatccagaa aacttttctt ggaagttagc ccctgaggaa tactttgaaa caccggtagc
     3181 tttagtgact cattcagatc agggattaac tggtattagt catgaaagtc agaattttgt
     3241 actgaagcac attatgctaa gtgaattttc taaaaaagaa cgtccaattc taatcaataa
     3301 ctgggaagct acttactttg actttcagag agaaaaactg ttagagttag cagatgaagc
     3361 taagaaagtt ggcattgaac tttttgtatt agatgatggt tggtttggca atcgttttga
     3421 tgataatcgt gctttaggtg attgggttgt taatgaggaa aaactgggtg gaagtctaga
     3481 aagtctgatt tcagctatcc atgaaagagg tttgcagttt ggactttggt tagaacccga
     3541 aatgatttct gtagatagtg atttgtatcg tcaacatcct gactgggcta ttcaggttcc
     3601 tgattatgag catacttatt ctcggaatca attagtactt aatcttgcca atcctcaggt
     3661 agtagaatac ttgaaaagtg tcttagatca actcctatct tatcatgaga ttgattacat
     3721 taaatgggat atgaaccgca atatcactaa gctagggaat ggattaactt atctagagac
     3781 acagatgcaa tctcatcagt acatgctggg gctttacgaa ctcgtttctt atctgacaga
     3841 gaagcacagc catattctct ttgagtcctg ctctggtggt ggtggacgaa atgatcttgg
     3901 tatgatacgc tatttcccac aagtctgggc tagtgataat actgatgcca ttgcacgttt
     3961 accaattcaa tacggttcat cctatctcta tccaaccatt tctatggggg ctcatgtgtc
     4021 agcagtaccg aatcatcaga tgggacgaat gacaccatta gaaacacgtg gccatgtagc
     4081 aatgatggga aatttgggct atgagcttga tttgacaaat ttatcagatg aagagaaagc
     4141 tacgattgct aatcaggtga acttgtataa agaattacga ccagtagttc agttaggaca
     4201 gcagtataga ctaattaatc ctgatactgt atccaatgaa gcagctgtac aatttaatta
     4261 cggaaatcaa acgattgtaa cctacgttcg cgttttatct gttgtagaga ccatggaaac
     4321 aactttaaaa ttaaaagatt tggatgaaga gggactatat aaattacagg aaaatggcga
     4381 agtttactca ggtgcagaac taatgtatgc gggcttaact gttatcttat cccaaggaga
     4441 ttttttgagt agacagtata tttttagaaa actatgatat gtactgaccc caaaagttag
     4501 atttattctg tctaactttt ggggtgcagt tcaataaggg tgtataaatt tataaaggag
     4561 gctttctaat ggaatggtat aaaaaaatcg gacttcttgc aactacaggt ttagctttgt
     4621 ttgggctcgg cgcttgctcc aactatggta aatctgcgga tggcacagtg accatcgagt
     4681 atttcaacca gaaaaaagaa atgaccaaaa ccttggaaga aatcactcgt gattttgaga
     4741 aggaaaaccc taagatcaag gtcaaagtcg tcaatgtacc aaatgctggt gaagtattga
     4801 agacacgcgt tctcgcagga gatgtgcctg atgtggtcaa tatttaccca cagtccatcg
     4861 aactgcaaga atgggcaaaa gcaggtgttt ttgaagattt gagcaacaaa gactacctga
     4921 aacgcgtgaa aaatggctac gctgaaaaat atgctgtaaa cgaaaaagtt tacaacgttc
     4981 cttttacagc taatgcttat ggaatttact acaacaaaga taaattcgaa gaactgggct
     5041 tgaaggttcc tgaaacctgg gatgaatttg aacagctagt caaagatatc gttgctaaag
     5101 gacaaacacc atttggaatt gcaggtgcag atgcttggac actcaatggt tacaatcaat
     5161 tagcctttgc gacagcaaca ggtggaggaa aagaagcaaa tcaatacctt cgttattctc
     5221 aaccaaatgc cattaaattg tcggatccga ttatgaaaga tgatatcaag gtcatggaca
     5281 tccttcgcat caatggctct aagcaaaaga actgggaagg tgctggctat accgatgtta
     5341 tcggagcctt cgcacgtggg gatgtcctca tgacaccaaa tgggtcttgg gcgatcacag
     5401 cgattaatga acaaaaaccg aactttaaga ttgggacctt catgattcca ggaaaagaaa
     5461 aaggacaaag cttaaccgtt ggtgcgggag acttggcatg gtctatctca gccaccacca
     5521 aacatccaaa agaagccaat gcctttgtgg aatatatgac ccgtccagaa gtcatgcaaa
     5581 aatactacga tgtggacgga tctccaacag cgatcgaagg agtcaaacaa gcaggagaag
     5641 attcaccgct tgctggtatg accgaatatg cctttacgga tcgtcacttg gtctggttgc
     5701 aacaatactg gaccagtgaa gcagacttcc ataccttgac catgaactat gtcttgaccg
     5761 gtgataaaca aggcatggtc aatgatttga atgccttctt taacccgatg aaagcggatg
     5821 tggattagga gtagagagac tatgaaaaaa gtattacaaa aatattgggc atgggctttt
     5881 gtggtcatcc ccctcttgtt acaagcaatt ttcttctatg tgccgatgtt tcaaggagcc
     5941 ttttacagtt ttaccaactg gacaggattg acttataact acaaatttgt cggcttaaac
     6001 aactttaagc tcctcttcat ggatccaaaa ttcatgaatg cgattggctt taccgcaatc
     6061 attacgattg ccatggtggt tggtgagatt gcactcggga tcttcattgc gcgtgtcttg
     6121 aattctaaaa tcaaaggcca aaccttcttc cgtgcttggt tcttcttccc agctgtttta
     6181 tctggtttga cagtggcttt gatcttcaag caagtcttca actacggtct tccagcgatt
     6241 gggaatgccc ttcatattga atttctccaa accagtcttt tagggactaa gtggggagca
     6301 atctttgcgg ctgtctttgt ccttctttgg caaggggtgg ctatgcccat catcatcttc
     6361 ctagctggtt tgcaatctat tccaactgag attacagagg cagcaaggat tgatggtgcg
     6421 acgagcaagc aagttttctg gaacattgaa ttgccttact tgctaccaag tgtctctatg
     6481 gtctttatcc tagccctaaa aggtgggctg actgcctttg accaagtctt tgccatgacc
     6541 ggtggtggtc caaacaatgc cacaacctca cttgggctct tggtttataa ctatgccttt
     6601 aaaaacaacc aattcggtta tgccaatgcc attgccgtaa tcttgttctt cttaattgta
     6661 gtgatttcga tcatccaatt gagagtatct aagaaatttg aaatttaaga ggagaagcat
     6721 gatgaaacaa gatgaaagaa aagccctgat tggcaaatac attctattga ttctaggatc
     6781 ggttctgatt ttagtgccgc tccttgctac cctctttagt tccttcaaac ccactaagga
     6841 tattgtagat aatttctttg gctttccaac caacttcaca tgggacaact ttagccgtct
     6901 cttagctgat gggattggag gctattattg gaactctgtc gtcatcactg tcttgtcttt
     6961 acttgcagta atgatcttta tacctatggc agcctactcc atcgctcgca atatgagtaa
     7021 aagaaaagcc tttaccatca tgtataccct cttaatcctc ggaatcttcg tacctttcca
     7081 agtcatcatg attccgatta cggttatgat gagtaaactc ggtttggcta atacctttgg
     7141 tttgatctta ctctacttga cctatgcgat tccacagacc ctctttctct atgttggcta
     7201 tatcaaaatc tcgattccag aaagtctgga tgaagcagca gagatcgatg gggctaatca
     7261 atttacaacc tatttccgca tcatcttccc aatgatgaaa ccgatgcatg cgacaaccat
     7321 gatcatcaat gccctttggt tctggaatga cttcatgttg ccactccttg tcttgaaccg
     7381 ggattccaaa atgtggactc tgcctttgtt ccaatacaac tacgcaggcc aatatttcaa
     7441 cgactacgga ccaagctttg cctcttacgt ggtcggcatt atcagtatca ccattgtcta
     7501 tctcttcttc caacgccata tcatttcagg aatgagcaac ggggcagtga agtaatactc
     7561 aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt tgctcaaaac actgttttga
     7621 ggttgtggat gaaactgacg aagtcagtaa ccatacctac ggtaaggtga agctgacgtg
     7681 gtttgaagag attttcgaag agtataagaa gagctcatgg aatctatagt ctttgacaca
     7741 gaggaagagt tcagcttgtt gataattcta tgtagaaaac aagaaagtag tactttgttt
     7801 atcacagtct atattagtac gagtttgatg ataaatagag atttaaaatg aatttgattt
     7861 acgaagccag atcatatgag acttggcttc aattagaaaa aggagagtaa tgatgccgat
     7921 tcaaaataaa accatgttga ttacctattc tgatagcctt ggaaataatc ttaaagactt
     7981 atatgataat ttggaagagc attttggaga tgctattgga ggagttcacc ttttaccatt
     8041 tttcccatca acaggtgatc gtggatttgc gccagttgac tacgacgaag tggactcagt
     8101 ttttggtgat tgggaggatg ttaagcgttt aggtgagaaa tattatctta tgtttgattt
     8161 tatgattaat catatttctc gtcaatccaa gtattataag gactatcaag aaaaacatga
     8221 agccagtgaa tttaaagctc tctttttaaa ctgggataag ttttggccag aaaaccgtcc
     8281 gacacagtct gatgtagatt taatttacaa gcgtaaggat cgtgcaccaa agcaagagat
     8341 tgtgtttgaa gatggttcag tggaacattt gtggaatacc tttggtgagg agcagattga
     8401 tcttgatgtg accaaagaag taactatgga atttatccgt aagaccattc agcacttggc
     8461 aagtaatggg tgtgatttga ttcgtctaga tgcctttgct tatgcagtga agaaattgga
     8521 tactaatgat ttctttgtgg aaccagatat ttgggattta ttggacaaag ttcgagatat
     8581 cgctgctgag tatgggacag agcttttacc tgagattcat gaacactatt cgattcagtt
     8641 taaaatagca gaccatgatt actatgttta tgattttgct cttccaatgg tgacacttta
     8701 tactctttac agttccagaa cagagcgttt ggctaagtgg ttaaagatga gcccgatgaa
     8761 gcaatttacg acgctagata cccatgatgg gattggagta gtagatgtca aggatatcct
     8821 gaccgatgag gagattgact atgcttcaaa tgaactctat aaggttggag ccaatgtcaa
     8881 acgtaagtac tctagtgccg agtataacaa cttagatatc taccaaatca attcaaccta
     8941 ctattcagcg cttggagatg atgatgtcaa gtattttctc gctcgtctaa ttcaagcttt
     9001 tgccccaggt attcctcagg tttactatgt gggtctatta gcaggcaaga atgacttgaa
     9061 attattagaa gaaactaaag aaggtcgaaa tattaatcgt cattactata gcaacgagga
     9121 aatagcaaaa gaagtgcaac gacctgttgt gaaggccctt ctcaatctat tttctttccg
     9181 taaccattca gaagcctttg atctagaagg gactactgag atagagacac caacagctca
     9241 cagcattgta atcaaacgtc aaaataaaga taagtccgta acagcagtag tagaaattga
     9301 tttgcaaaat cagacttatc gggtaattga gaatggagtt gaagtatcat tttgaagcct
     9361 tgatatggtg gataaaatag ggtttttatt ttggaaaacg tttcctttgt tttcaaattg
     9421 ctaaaaaagt ggtacaatat aggatagctt actattatct gaatcagctg atttggagag
     9481 aaaggattca ttttgaaatc aataggcttt attgaaaagc tgaaggggtt gtctagtaaa
     9541 gagctgattt tattgggaat tatcctaagt atctttttac ccttttatct ttttgtagtt
     9601 gtactctgtt tatatattat cagtttgatt tttacaggag acatgaaaag tattcttcag
     9661 aaaatggggg agcatccgat gctgcttctt tttcttagct atagtactgt tatatccatt
     9721 cttgcacaaa attggatggg tcttgtggct tcagtaggaa tgtttctatt tactattttc
     9781 tttttgcact atcagtcgat tttatcccat aaattctttc gattgatttt gcagttcgtc
     9841 ttgtttggta gtgtcttgtc agctgctttt gccagtttag aacatttcca aattgtgaag
     9901 aaatttaact atgcttttct ttcacccaat atgcaggtgt ggcatcagaa ccgggcagaa
     9961 gtgaccttct ttaatcctaa ttattatgga attatttgtt gtttctgtat tatgattgct
    10021 ttctatctgt ttacaacgac caagttgaat tggttgaaag tattctgtgt gattgcaggc
    10081 tttgttaatc tctttggttt gaactttact caaaatcgaa ctgcctttcc tgctattatc
    10141 gctggagcaa ttatctatct ctttacgact attaaaaact ggaaggcctt ttggcttagt
    10201 attggggtct tcgcgattgg tttgagtttc ctcttttcta gtgatttggg agttcgaatg
    10261 ggtactttag actcttctat ggaagaacgc atttctatct gggatgctgg gatggccttg
    10321 tttaagcaaa atcctttttg gggtgaaggg ccattgacct atatgcactc ttatcctcgg
    10381 atacatgctc cttatcatga acatgcccac agtctttata ttgatacgat tctgagttac
    10441 ggaattgtgg gtaccatttt attagttttg tcttctgttg ctcctgttcg cttgatgatg
    10501 gatatgagtc aggagtcggg gaaacgtccg attatcggcc tttatctatc tttccttaca
    10561 gtggttgctg tgcacggaat ttttgacttg gctctcttct ggattcagtc aggctttatt
    10621 ttcttgctag ttatgtgcag tattccattg gagcatcgaa tgttggtatc ggacatgacg
    10681 gattaagttt tataagtttg aaatcttcta ccttgggtag gagatttttt tatacgatgg
    10741 gcatgtcgtg catctgaggt gtaagtcctc tgtagggatc cactaccggt gaatacaata
    10801 gcgctcccca agcctgacta tcgtgaggta gcggattaaa atggtctggg gatagatcgt
    10861 tttaagtctg acgcaggaaa taagaattgt cagagaaagc aatagtgaaa tcgtaggcta
    10921 tgaatagaaa cgtgatagcg aggagcatat agtggataag gtagcgagaa attttaaagt
    10981 ataaaagata gtcttaatct atatatgtaa atcacaaaag taattgaatt cggaataagg
    11041 ttggtgtgaa aagacatagt aaactgaatc ttgaatacta gaatgatact tctacaatat
    11101 tgttataatt taatttgaat tccaaaatca cattgttccg tccgtatttc attttactgt
    11161 atgtcttcct aaactccaaa gtttctgcgt caaatttcct attttcactg tagtctttga
    11221 cacttcgaac gacaatttga atcatatatt caaaaaaaat gaaaaatttg tgccaacaag
    11281 cctaaatatt ctgaaaattt gtttgatttt taatggataa tgtgatataa tggttgtcaa
    11341 tctataattc acataaacag aggagtagaa aatgaaaaaa aatcgtgtat ttgctacagc
    11401 aggtcttgtt ttattagcag caggtgtact tgcagcatgc agttcttcaa aatcatctga
    11461 ttcatcagcc cctaaagctt atggctatgt ttatacagca gacccagaaa ccttggacta
    11521 cctgatttca agtaaaaata gtacaacagt agtgacttca aatgggattg atggtttatt
    11581 cactaacgat aattacggta atcttgctcc tgcagttgca gaggattggg aagtctctaa
    11641 ggatggtttg acctacactt ataagattcg taaaggggtt aaatggttta cctctgatgg
    11701 agaagaatat gcagaggtga cggctaaaga tttcgtgaac ggtttaaaac acgcagcaga
    11761 taaaaaatca gaagctatgt atttagctga aaattcggtt aaaggcttgg cagattatct
    11821 atcaggaact tcaacagatt tttcaacagt tggtgtcaag gcggttgatg attatacgtt
    11881 acaatacact ttgaaccagc ctgaaccgtt ctggaactct aagttgacct attctatttt
    11941 ctggcctctg aatgaagaat tcgaaacatc aaaaggaagc gattttgcta aaccaacaga
    12001 tccgacatcc ttgctttata atggtccatt cttgttgaaa gggttgactg caaaatcttc
    12061 tgtagagttt gtaaaaaatg agcaatattg ggataaagaa aatgtccacc tagatactat
    12121 taatctagct tactatgatg gatcagatca ggagtcgcta gagcgtaact tcactagtgg
    12181 agcttatagt tatgcccgtc tttaccctac cagctccaac tattctaagg ttgcagaaga
    12241 atacaaggac aatatctatt acacacaatc aggctctggg attgctggtc tgggtgtgaa
    12301 tattgatcgc caaagttaca actatacttc taaaactaca gattcagaga aagtagctac
    12361 taagaaggca ttgcttaaca aagatttccg tcaagccttg aattttgctc ttgatcgctc
    12421 agcttactca gctcaaatca atggtaaaga tggagcagct ttagcagttc gtaatttatt
    12481 tgtaaaacca gactttgttt cagctggtga gaagaccttt ggtgatttag tcgctgctca
    12541 acttcctgct tatggtgatg agtggaaagg tgtgaattta gctgatgggc aggatggttt
    12601 attcaatgct gacaaggcca aggcagagtt tgcgaaagct aagaaagctt tagaagcaga
    12661 cggcgttcag tttcctattc atctggacgt tccagtagac caagcatcaa aaaactacat
    12721 atctcgtatt cagtccttta aacaatctgt agaaacagtt cttggtgttg aaaatgtcgt
    12781 tgttgatatt caacaaatga caagtgatga attccttaat attacttact atgctgccaa
    12841 tgcttcatct gaggattggg atgtatcagg aggagtttca tgggggccag actatcaaga
    12901 cccatctact tacctggata ttttaaaaac aactagcagt gaaactacaa aaacatattt
    12961 aggatttgat aatccaaata gcccttcagt agttcaagtt ggtttgaaag aatacgataa
    13021 attagttgat gaagctgcca gagagacaag cgacttgaat gtccgttatg aaaaatatgc
    13081 agcggctcaa gcatggttga cagatagttc actctttatt cctgctatgg cttcttctgg
    13141 tgcagcacca gtgctttcac gaattgttcc atttactgga gcttctgcgc aaacaggctc
    13201 taaggggtca gatgtttact tcaaatattt gaaattacaa gataaagtgg tgactaagga
    13261 agagtatgaa aaagctcgtg aaaaatggtt gaaagaaaaa gctgaatcaa atgagaaagc
    13321 tcaaaaagaa ttggcaagtc atgtgaagta aataatttct aatagaactt tctctccatg
    13381 aggagaaggt tcttttggga tttttaaagg aaataatatg aaaaaatata tttttatgcg
    13441 tgttttgcgg tcattggttt cgattttctt agtaacgact ttgacctaca cgattatcta
    13501 taccttggtt cctcgaaaat tgattttcaa gcaggatcct aactataata aaattgcgac
    13561 aacggctgat aaacgtgata actatgaaaa tactgtgttt gagcgtatgg gctacattga
    13621 gtattacgat actaaagagt tgcaagaaaa ggcaagtagc atggattctt ctgtaacagt
    13681 agaagcaaat gcgaccaata aagctattta tgaaaagtac atcaatcaat taggtcatgg
    13741 ttggactttg ggagaattta ctgaaagtgg tcaattctat gctactcgtg aaattccaat
    13801 ttttgaacgt gtttttcact tctatgctaa cttgattgac attgatcata caaataaaat
    13861 ccaagaccct gaaaatccag acttgaaacg ctaccttcgt tttgaaaatg atccagctat
    13921 cggatggtca ttggtcggtt caggaactaa acataaatat ctcttgtact ttaacagtca
    13981 gttcccattt gttcatcaaa actttgtgaa cttgaattta ggtgactctt acccaaccta
    14041 tgctaataca ccagttcttc aggttattac tcaaggtcaa ggacaaacca aaactgccca
    14101 agttcagttc ccaacaggta agaaaacgtc ttctgtaaat atttactcaa gaacctacaa
    14161 gtcacctagt caggctgact ctcgtgaagt agctagctat gggaaagatg atccttatac
    14221 agcgactgaa agtaattacc aatatccatc tatgattgtc agctctgcta ttactggttt
    14281 gattggtttg gttcttgcct atgctcttgc cgtgccactt ggttcagcca tggctcgttt
    14341 caagaacact tggattgata gcctctcaac agggactttg accttcttgc ttgctcttcc
    14401 aacgattgcc ttggtttaca tcgttcgatt gattggatca tctattgccc ttccagattc
    14461 attccctatc ttgggagctg gagattggcg ttcttacgtt ttaccagcag tcatccttgg
    14521 tttgttgggt gctcctgtta cagccatttg gattcgtcgt tacatgattg acttgcaatc
    14581 tcaagacttt gttcgtttcg ctcgtgcaaa aggtttgtct gaaaaagaaa tttcaaacaa
    14641 acacatcttt aaaaatgcca tggttccgct ggtttcagga attcctggtg ccattattgg
    14701 ggttatcggt ggtgcaaccc ttactgaaac agtcttcgcc ttcccaggta tgggtaaaat
    14761 gttgattgac tctgtaaaag catctaataa ctctatggtc gttggtcttg tcttcatctt
    14821 tacatgtatt tctatcttct cacgtctttt gggagatatt tggatgacta ttattgaccc
    14881 acgtattaaa ttgactgaga aaggaggcaa ataatgtcta caatcgataa agaaaaattt
    14941 cagtttgtaa aacgtgacga ttttgcctct gaaactattg atgcgccagc atattcttac
    15001 tggaaatcag tgtttaaaca atttatgaag aaaaaatcaa ctgtagtcat gttgggaatc
    15061 ttggtagcca tcattttgat aagtttcatc tacccaatgt tttctaagtt tgatttcaat
    15121 gatgtcagca aggtaaacga ctttagtgtt cgttatatca agccaaatgc ggagcattgg
    15181 ttcggtactg acagtaacgg taaatcgctc tttgacggtg tctggttcgg agctcgtaac
    15241 tccatcctca tttctgtgat tgcgacagtg attaacgtgg ttatcggtgt ttttgtcggt
    15301 ggtatttggg gtatttcaaa atcagttgac cgtgtcatga tggaagttta caacgtcatc
    15361 tcaaacatcc cacctctttt gattgttatt gtcttgactt actcaatcgg agctggattc
    15421 tggaatctga tttttgccat gagcgtaaca acatggattg gtattgcctt catgatccgt
    15481 gtgcaaatct tgcgctatcg tgacttggaa tacaacttgg cgtcacgtac tttgggaaca
    15541 ccaaccttga agattgttgc caaaaatatc atgcctcaat tggtatctgt tattgtgaca
    15601 accatgactc aaatgcttcc aagctttatc tcatacgaag ccttcttgtc tttcttcggt
    15661 cttggattac cgattacagt gccaagtttg ggtcgtttga tttcggatta ttcacaaaac
    15721 gtaacaacca atgcttactt gttctggatt ccattgacaa cccttgtctt ggtatccttg
    15781 tcccttttcg tagttggtca aaacttagcg gatgctagtg atccacgtac acatagatag
    15841 gagtagaaat gacaaaagaa aaaaatgtaa ttttgactgc tcgcgatatt gtcgtggaat
    15901 ttgacgttcg tgacaaagta ttgacagcca ttcgcggcgt ttcccttgaa ctagtcgaag
    15961 gagaagtatt agccttggta ggtgagtcag gatcaggtaa atctgttttg acaaagacct
    16021 tcacaggtat gctcgaagaa aatggtcgta ttgcccaagg tagtattgac taccgtggtc
    16081 aggacttgac agctttatct tctcacaagg attgggaaca aattcgtggt gctaagattg
    16141 cgactatctt ccaggaccca atgactagtt tggaccccat taaaacaatt ggtagtcaga
    16201 ttacagaagt tattgtaaaa caccaaggaa aaacagctaa agaagcgaaa gaattggcca
    16261 ttgactacat gaataaggtt ggcattccag acgcagatag acgttttaat gaatacccat
    16321 tccaatattc tggaggaatg cgtcaacgta tcgttattgc gattgccctt gcctgccgac
    16381 ctgatgtctt gatctgtgat gagccaacaa ctgccttgga tgtaactatt caagctcaga
    16441 ttattgattt gctaaaatct ttacaaaacg agtatcattt cacaacaatc tttattaccc
    16501 acgaccttgg tgtggtggca agtattgcgg ataaggtagc ggttatgtat gcaggagaaa
    16561 tcgttgagta tggaacggtt gaggaagtct tctatgaccc ttgccatcca tatacatgga
    16621 gtctcttgtc tagcttgcct cagcttgctg atgataaagg ggatctttac tcaatcccag
    16681 gaacacctcc gtcactttat actgacctga aaggggatgc ttttgccttg cgttctgact
    16741 acgcaatgca gattgacttc gaacaaaaag ctcctcaatt ctcagtatca gagacacatt
    16801 gggctaaaac ttggcttctt catgaggatg ctccaaaagt agaaaaacca gctgtgattg
    16861 caaatctcca tgataagatc cgtgaaaaaa tgggatttgc ccatctggct gactaggagg
    16921 aaggaaatgt ctgaaaaatt agtagaaatt aaagatttag aaatttcctt cggtgaagga
    16981 agtaagaagt ttgtcgcggt taaaaatgct aacttcttta tcaacaaggg agaaactttc
    17041 tcgcttgtag gtgagtccgg tagtgggaaa acaactattg gtcgtgctat catcggtcta
    17101 aatgatacaa gtaatggaga tatcattttt gatggtcaaa agattaatgg taagaaatcg
    17161 cgtgaacaag ctgcggaatt gattcgtcga atccagatga ttttccaaga ccctgccgca
    17221 agtttgaatg aacgtgcgac tgttgattat attatttctg aaggtcttta caatcaccgt
    17281 ttatttaagg atgaagaaga acgtaaagag aaagttcaaa atattatccg tgaagtaggt
    17341 cttcttgctg agcacttgac tcgttaccct catgaattct caggcggtca acgtcaacgt
    17401 atcggtattg cccgtgcctt ggtcatgcaa ccagactttg ttattgcaga tgagccaatt
    17461 tcagccttgg acgtttctgt acgtgcccaa gtcttgaact tgctcaaaaa attccaaaaa
    17521 gagctcggcc tgacctatct cttcatcgcc catgacttgt cggttgttcg ctttatttca
    17581 gatcgtatcg cagttattta caagggtgtt attgtagagg ttgcagaaac agaagaattg
    17641 tttaacaatc caattcaccc atatactcaa gccttgcttt cagcggtacc aatcccagat
    17701 ccaatcttgg aacgtaagaa ggtcttgaag gtttacgatc caagtcaaca cgactatgag
    17761 actgataagc catctatggt agaaatccgt ccaggtcact atgtttgggc gaaccaagcc
    17821 gaattggcac gttatcaaaa aggactaaac tagtaatggt tttataattt ccatgtcaat
    17881 ttttatggaa attaggctct ttgtcaactg tagtgggttg aagtcagcta agctcgagaa
    17941 aggacaaatt tcgtcctttc ttttttgatg ttcaaagcga taaaaatccg ttttttgaag
    18001 ttttcaaagt ttcgaaaacc aaaggcattg cgcttgataa gtttgatgag attattggtc
    18061 gcttccagtt tggcattaga atagtgtagt tgaagggcgt tgataatctt tt
//
LOCUS       DAVHSY010000037        17993 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.038, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000037 DAVHSY010000000
VERSION     DAVHSY010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17993
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.038"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..71
                     /locus_tag="VVR43_001587"
     CDS             <1..71
                     /locus_tag="VVR43_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEU6149926.1"
                     /translation="IPAMSAPVFDNIEAAIKEHGLS"
     gene            119..1594
                     /locus_tag="VVR43_001588"
     CDS             119..1594
                     /locus_tag="VVR43_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU6149927.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLRGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            1989..8690
                     /locus_tag="VVR43_001589"
     CDS             1989..8690
                     /locus_tag="VVR43_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU6149928.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWHF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNNFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTANVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIEAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(8938..9795)
                     /locus_tag="VVR43_001590"
                     /pseudo
     CDS             complement(8938..9795)
                     /locus_tag="VVR43_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10006..10365)
                     /locus_tag="VVR43_001591"
     CDS             complement(10006..10365)
                     /locus_tag="VVR43_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU6149929.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLIMYIEMVVELFLMK"
     gene            10457..11414
                     /locus_tag="VVR43_001592"
                     /pseudo
     CDS             10457..11414
                     /locus_tag="VVR43_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; frameshifted;
                     internal stop; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11398..11955
                     /locus_tag="VVR43_001593"
     CDS             11398..11955
                     /locus_tag="VVR43_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6149930.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            11948..12202
                     /locus_tag="VVR43_001594"
     CDS             11948..12202
                     /locus_tag="VVR43_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149931.1"
                     /translation="MDKQYLREKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12214..14268
                     /locus_tag="VVR43_001595"
     CDS             12214..14268
                     /locus_tag="VVR43_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU6149932.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHSFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14447..15307
                     /locus_tag="VVR43_001596"
     CDS             14447..15307
                     /locus_tag="VVR43_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU6149933.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLRDPVFKKD"
     gene            15518..16228
                     /gene="ccdA2"
                     /locus_tag="VVR43_001597"
     CDS             15518..16228
                     /gene="ccdA2"
                     /locus_tag="VVR43_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU6149934.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16248..16814
                     /locus_tag="VVR43_001598"
     CDS             16248..16814
                     /locus_tag="VVR43_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU6149935.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            16825..17937
                     /gene="msrB"
                     /locus_tag="VVR43_001599"
     CDS             16825..17937
                     /gene="msrB"
                     /locus_tag="VVR43_001599"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU6149936.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISEDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         5415 a         3417 c         3972 g         5189 t
ORIGIN      
        1 gtatcccagc aatgagcgct ccagtatttg acaatattga agcagctatt aaagaacatg
       61 gattaagcta attctaattt gttaacattc atataacata aaaaagggag gaactgttat
      121 ggatgcaatc tttgacctaa tcggaaaggt tttcaatccc atcttagaaa tgggtggacc
      181 tgtcatcatg ttgatcattt tgacagtatt ggctttactt tttggagtga aattctccaa
      241 agcgcttgaa ggtggtatca aacttgccat cgctcttaca ggtatcggtg ctatcatcgg
      301 tatgctaaat ggtgctttct cagcatcact tgcaaaattc gttgaaaaca ctggtatcca
      361 attgagtatt acagacgttg gttgggcacc actcgcaaca atcacttggg gttctgcttg
      421 gacactatac ttcttgctca tcatgttgat tgtcaacgta gtgatgcttg ctatgaagaa
      481 aaccgataca cttgatgtcg atatctttga tatctggcac ttgtctatca caggtctctt
      541 gattaaatgg tatgctgata acaatggtgt gagtcaaggg gtttcactct ttattgctac
      601 agcagctatc gtccttgtcg gtgtgttgaa aattatcaac tctgacttga tgaaacctac
      661 atttgatgac cttcttaacg ccccaagttc atcaccaatg acatcaactc acatgaacta
      721 catgatgaac ccagttatca tggttttgga taagattttt gaaaaattct tcccaggcct
      781 tgataaatat gactttgatg ctgctaaatt gaacaagaaa atcggtttct ggggatctaa
      841 attcttcatc ggtttcatcc ttggtatcgt tatcggtatt atgggaactc cacatccaat
      901 tgcaggtgtt gcagatgcag ataaatggcg tcttgttatc aaaggatggt tgtctcttgg
      961 tttgactgcc ggtgtatctt tggaactctt ctcacttatc ggttcatggt tcatcgcagc
     1021 cgtagaacca ctatcacaag gtattacaaa cgttgctact aaacgtcttc gaggacgtaa
     1081 attcaatatc ggtcttgact ggccattcat cgctggtcgt gctgaaatct gggcttgtgc
     1141 caacgtactt gcaccaatca tgttgattga agcagtgctt ctttcaaaag ttggaaatgg
     1201 tatcttgcca cttgcaggta tcatcgctat gggtgttact ccagctctct tggttgtaac
     1261 tcgtggtaaa ttgctccgta tgattatctt cggaacactc ttgttgccac tcttccttct
     1321 ttcaggtaca cttattgcac catttgcaac agaacttgct aaaggtgtag gtgccttccc
     1381 agaaggtgtg agccaaactc aattgattac tcactctact cttgaaggac caatcgaaaa
     1441 acttcttggt tggacaattg gtaacactac aactggtgat atcaaagcaa tccttggtgc
     1501 agtagtcttc cttgtattct atatcggtat ctttgcttgg tacagaaaac aaatgatcaa
     1561 acgtaacgaa gagtacgcag caaaagcaaa ataatgcgct cctataaaat ataaactcaa
     1621 tgaaaatcaa agagcaaact aggaaactag ccgcaggttg ctaaaaacac agttttgagg
     1681 ttgtagataa gactgacgaa gtcagctcaa aacatggttt tgaggttgta gatgaaactg
     1741 acgaagtcag ctcaaaacat ggttttgagg ttgtagatga aactgacgaa gtcagctcaa
     1801 aacatggttt tgaggttgta gatgaaactg acgaagtcag taatcatatc tacggcaagg
     1861 cgacgctgac gaagtttgaa ttggattttc gcagagtgta aattgttgaa actaggttgt
     1921 cataccatgt ataccacttg ggctttggta gtagctaact gcactaaata taatataagg
     1981 agggttttat ggggaaaggc cattggaatc ggaaaagagt ttatagcatt cgtaagtttg
     2041 ctgtgggagc ttgctcagta atgattggga cttgtgcagt tctattagga ggaaatatag
     2101 ctggagaatc tgtagtttat gcggatgaaa cacttattac tcatactgct gagaaaccta
     2161 aagaggaaaa aatgatagta gaagaaaagg ctgataaagc tttggaaact aaaaatgtag
     2221 ttgaaaggac agaacaaagt gaacctagtt caactgaggc tattgcatct gagaagaaag
     2281 aagatgaagc cgtaactcca aaagaggaaa aagtgtctgc taaaccggaa gaaaaagctc
     2341 caaggataga atcacaagct tcaagtcaag aaaaaccgct caaggaagat gctaaagctg
     2401 taacaaatga agaaatgaat caaatgattg aagacaggaa agtggatttt aatcaaaatt
     2461 ggcactttaa actcaatgca aattctaagg aagccattaa acctgatgca gacgtatcta
     2521 cgtggaaaaa attagattta ccgtatgact ggagtatctt taacaatttc gatcatgaat
     2581 ctcctgcaca aaatgaaggt ggacaactca acggtgggga agcttggtat cgcaagactt
     2641 tcaaactaga tgaaaaagac ctcaagaaaa atgttcgcct tacttttgat ggcgtctaca
     2701 tggattctca agtttatgtc aatggtcagt tagtggggca ttatccaaat ggttataacc
     2761 agttctcata tgatatcacc aaataccttc acaaagatgg tcgtgagaat gtgattgctg
     2821 tccatgcagt caacaaacag ccaagtagcc gttggtattc aggaagtggt atctatcgtg
     2881 atgtgacttt acaagtgaca gataaggtgc atgttgagaa aaatgggaca actattttaa
     2941 caccaaaact tgaagaacaa caacatggca aggttgaaac tcatgtgacc agcaaaatcg
     3001 tcaatacgga cgacaaagac catgaacttg tagccgaata tcaaatcgtt gaacgaggtg
     3061 gtcatgctgt aacaggctta gttcgtacag cgagtcgtac cttaaaagca catgaatcaa
     3121 caagcctaga tgcgatttta gaagttgaaa gaccaaaact ctggaccgtt ttaaatgaca
     3181 aacctgcctt gtacgaattg attacgcgtg tttaccgtga cggtcaattg gttgatgcta
     3241 agaaggattt gtttggttac cgttactatc actggactcc aaatgaaggt ttctctttga
     3301 atggtgaacg tattaaattc catggagtat ccttgcacca cgaccatggg gcgcttggag
     3361 cagaagaaaa ctataaagca gaatatcgcc gtctcaaaca aatgaaggag atgggagtta
     3421 actctatccg tacaacccac aaccctgcta gtgagcaaac cttgcaaatc gcagcagaac
     3481 taggtttact cgttcaggaa gaggcctttg atacgtggta tggtggcaag aaaccttatg
     3541 actatggacg tttctttgaa aaagatgcca ctcacccaga agctcgaaaa ggtgaaaaat
     3601 ggtctgattt tgacctacgt accatggtcg aaagaggcaa aaacaaccct gctatcttca
     3661 tgtggtcaat tggtaatgaa ataggtgaag ctaatggtga tgcccactct ttagcaactg
     3721 ttaaacgttt ggtcaaggtt atcaaggatg ttgataagac tcgctatgtt accatgggag
     3781 cagataaatt ccgtttcggc aatggtagcg gagggcatga gaaaattgct gatgaactcg
     3841 atgctgttgg atttaactat tctgaagata attacaaagc ccttagagct aagcatccaa
     3901 aatggttgat ttacggttca gaaacatcat cagcaacccg tacacgagga agttactatc
     3961 gccctgaacg tgaattgaaa catagcaatg gacctgagcg taattatgaa cagtcagatt
     4021 atggaaatga tcgtgtgggt tgggggaaaa cagcaaccgc ttcatggact tttgaccgtg
     4081 acaacgctgg ctatgctgga cagtttatct ggacaggtac ggactatatt ggtgaaccta
     4141 caccatggca caaccaaaat caaactcctg ttaagagctc ttactttggt atcgtagata
     4201 cagccggcat tccaaaacat gacttctatc tctaccaaag ccaatgggtt tctgttaaga
     4261 agaaaccgat ggtacacctt cttcctcact ggaactggga aaacaaagaa ttagcatcca
     4321 aagtagctga ctcagaaggt aagattccag ttcgtgctta ttcgaatgct tctagtgtag
     4381 aattgttctt gaatggaaaa tctcttggtc ttaagacttt caataaaaaa caaaccagcg
     4441 atgggcggac ttaccaagaa ggtgcaaatg ctaatgaact ttatcttgaa tggaaagttg
     4501 cctatcaacc aggtaccttg gaagcaattg ctcgtgatga atctggcaag gaaattgctc
     4561 gagataagat tacgactgct ggtaagccag cggcagttcg tcttattaag gaagaccatg
     4621 cgattgcagc agatggaaaa gacttgactt acatctacta tgaaattgtt gacagccagg
     4681 ggaatgtggt tccaactgct aataatctgg ttcgcttcca attgcatggc caaggtcaac
     4741 tggtcggtgt agataacgga gaacaagcca gccgtgaacg ctataaggcg caagcagatg
     4801 gttcttggat tcgtaaagca tttaatggta aaggtgttgc cattgtcaaa tcaactgaac
     4861 aagcagggaa attcacactg acagcccact ctgatctctt gaaatcgaac caagtcactg
     4921 tctttactgg taagaaagaa ggacaagaga agactgtttt ggggacagaa gtgccaaaag
     4981 tacagaccat tattggagag gcacctgaaa tgcctaccac tgttccgttt gtatacagtg
     5041 atggtagccg tgcagaacgt cctgtaacct ggtcttcagt agatgtgagc aagcctggta
     5101 ttgtaacggt gaaaggtatg gctgacggac gagaagtaga agctcgtgta gaagtgattg
     5161 ctcttaaatc agagctacca gttgtgaaac gtattgctcc aaatactgac ttgaattctg
     5221 tagacaaatc tgtttcctat gttttgactg atggaagtgt acaagagtat gaagtagata
     5281 gctgggagat tgccgaagaa gataaagcta agttagcaat tccaggttct cgtattcaag
     5341 cgaccggtta tttagaaggt caaccaattc atgcaaccct tgtggtagaa gaaggcaatc
     5401 ctgcagcacc tgtagtgcca actgttactg ttggaggtga agcagtaaca ggtcttacta
     5461 gtcgacaacc aatgcaatat cgtactctat cttatggtgc ccaattgcca gaagtcacag
     5521 caagtgctga aaatgctgat gtgacagttc ttcaagcaag cgcagcaaac ggcatgcgtg
     5581 cgagcatctt tattcagcct aaagatggtg gccctcttca aacctatgca attcaattcc
     5641 ttgaagaagc gccaaaaatt gctcacttga gtttgcaagt ggaaaaagct gacagtctca
     5701 aagaagacca aactgtcaaa ttgtcggttc gagctcacta tcaagatgga acgcaagctg
     5761 tattaccagc tgataaagta accttctcta caagtggtga aggggaagtc gcaattcgta
     5821 aaggaatgct tgagttgcat aagccaggag cagtcactct gaacgctgaa tatgagggag
     5881 ctaaaggcca agttgaactc actatccaag ccaatactga gaagaagatt gcgcaatcta
     5941 tccgtcctgt aaatgtagtc acagatttgc atcaaaaacc tactcttcca acaacagtaa
     6001 cggttgagta tgacaaaggt ttccctaaag ctcacaaagt cacttggcaa gctattccga
     6061 aagaaaaact agactcctat caaacatttg aagtactagg taaagttgaa ggaattgacc
     6121 ttgaagcgcg tgcaaaagtc tctgtagaag gtatcgtttc agttgaagaa gtcagtgtga
     6181 caactccaat cgcagaagca ccacaattac cagaaagcgt tcggacatat gattcaaatg
     6241 gtcacgtttc atcagctaag gttgcatggg atgcgattcg tatagagcaa tacgctaagg
     6301 aaggtgtctt tacagttaat ggtcgcttag aaggtactca attaacaact aaacttcatg
     6361 ttcgcgtatc tgctcaaact gagcaaggtg caaacatttc tgaccaatgg accggttcag
     6421 aattgccact tgcctttgct tcagattcaa atccaagcga cccagtttca aatgttaatg
     6481 acaagctcat ttcctacaat aaccaaccag ccaatcgttg gacaaactgg aatcgtagta
     6541 atccagaagc ttcagtcggt gttctgtttg gagattcagg tatcttgagc aaacgctccg
     6601 ttgataatct aagtgtcgga ttccacgaag accatggagt tggtgcaccg aagtcttatg
     6661 tgattgagta ttatgttggt aagactgtcc caacagctcc taaaaaccct agttttgttg
     6721 gtaatgagga ccatgtcttt aatgattctg ccaactggaa accagttact aatctaaaag
     6781 cccctgctca actcaaggct ggagaaatga accactttag ctttgataaa gttgaaacct
     6841 atgctgttcg tattcgcatg gttaaagcag ataacaagcg tggaacgtct atcacagagg
     6901 tacaaatctt tgcgaaacaa gttgcggcag ccaaacaagg acaaacaaga atccaagttg
     6961 acggcaaaga cttagcaaac ttcaaccctg atttgacaga ctactacctt gagtctgtag
     7021 atggaaaagt tccggcagtc acagcaaatg ttagcaacaa tggtctcgct accgtcgttc
     7081 caagcgttcg tgaaggtgag ccagttcgtg tcatcgcgaa agctgaaaat ggcgacatct
     7141 taggagaata ccgtctgcac ttcactaagg ataagaactt actttctcat aaaccagttg
     7201 ctgcggttaa acaagctcgc ttgctacaag taggtcaagc acttgaattg ccgactaagg
     7261 ttccagttta cttcacaggt aaagacggct acgaaacaaa agacctgaca gttgaatggg
     7321 aagaagttcc agcggaaaat ctgacaaaag caggtcaatt tactgttcga ggccgtgtcc
     7381 ttggtagtga ccttgttgct gaggtcactg tacgagtgac agacaaactt ggtgaggctc
     7441 tttcagataa ccctaactat gatgaaaaca gtaaccaggc ctttgcttca gcaaccaatg
     7501 atattgacaa aaactctcat gaccgcgttg actatctcaa tgacggagat cattcagaaa
     7561 atcgtcgttg gacaaactgg tcaccaacac catcttctaa tccagaagta tcagcgggtg
     7621 tgatcttccg tgaaaatggt aagattgtag aacggactgt tgcgcaagcc aaacttcact
     7681 tctttgcaga tagtggtacg gatgcaccaa ctaaactcgt tttagaacgc tatgtcggtc
     7741 cagagtttga agtgccaacc tactattcaa actaccaagc ctacgacgca gaccatccat
     7801 tcaacaatcc agaaaattgg gaagctgtgc cttatcgtgc ggataaagac attgaagccg
     7861 gtgatgaaat taacgttacc tttaaagctg tcaaagccaa agccatgaga tggcgtatgg
     7921 agcgtaaagc agataagagc ggtgttgcga tgattgagat gaccttcctt gcaccgagtg
     7981 aattgcctca agaaagcact caatcgaaga ttcttgtaga tggaaaagag cttgctgatt
     8041 tcgctgaaaa tcgtcaagac tatcaaatta cctataaagg tcaacggcca aaagtctcag
     8101 ttgaagaaaa taatcaagta gcttcaactg tggtagatag tggagaagat agccttccag
     8161 tacttgttcg cctcgtttca gaaagtggaa aacaagttaa ggaataccgt atccagttga
     8221 ctaaggaaaa accagtttct gagaagacag ttgctgctgt acaagaagat cttccaaaac
     8281 tcgaatttgt tgaaaaagat ttggcctaca agacagttga gaaaaaagat tcaacactgt
     8341 atctaggtga aactcgtgta gaacaagaag gaaaaactgg taaagaacgt atctttacag
     8401 cgattaatcc tgatggaagt aaggaagaaa aactccgtga agtggtagaa gctccgacag
     8461 accgcatcgt cttggttgga accaaaccag tagctcaaga agctaaaaaa ccacaagtgt
     8521 cagaaaaagc agatacaaaa ccaattgatt caagtgaagc tagtcaaact aataaagccc
     8581 agttaccaaa tacaggtagt gcggcaagcc aagcagcagt agcagcaggt ttagctcttc
     8641 taggtttgag tgcaggatta gtagttacta aaggtaaaaa agaagactag aaattttgat
     8701 accttcttta tcattaaaga ccaaagaaaa actcttgtcc taaatagaag ataaagagtc
     8761 tgggacaaaa tagttctcaa ccacaaaaaa gctagatatt tccaattgcg gaactctagc
     8821 tttttaattt tgagtcgttc tcttattgta tagtagattg aaactagagt agtacacttc
     8881 tacttctaaa acattgttag aaatcgattt gactgtcctt attgatttgt cctgttctta
     8941 tttcatttca ctatgtttta ggaggttatt ggccataagt accaatccca tgtcaattct
     9001 cacttgacgc ttgcctctca gattacatct cttgtaaccc aaacaagcct ttaactgccc
     9061 aaagacaggt tccacatcaa tcttgcgttg agcgaaaatc tgtctacctt ggggagataa
     9121 aagcgcctga cattctttag ctttcaagtt ttgatagcgt tcgttcatat atagccccct
     9181 tttgaggggc tgattcaggt tcgtcggcat agtaaacctt gatttcctgt tgaaagtctg
     9241 tctgtgtttt ctgatgtttg gtatggtgaa aacgataata ccagccatca ggatgtgtgt
     9301 agctatcctc cttgtcatta tagtgccaat tcgctaagtt tttagctgac tgtttatacc
     9361 ctctcttttg ttccttatca aacatggcat atttaatcag aaggggagtg atttcttctt
     9421 gaaaatagac ttgtatctgt tcttgaagtt tggcggagaa tttctctgtc gttttcttcc
     9481 acacaaaact atacttgttg gcattggatt caatcttagt tccgtcaata aacaaacaat
     9541 ctaaggtcac taactcttcc atttttcaat ttttcgacca gagaaaatcc cttgtgaata
     9601 gacaaataga agagtagata caagcatttt agggtgataa gacgggcgat caaaggcatg
     9661 atagaaggcg tagaagtgat gttcctccaa ggtattcacc actttttcaa tagtaaagac
     9721 gagatggtct tgtggtaaga aggaactgat ttctagtggt aaagttgttt gatttgtgtt
     9781 atagtgaata tgcatgggat agcctttcta aatggtttat tgtgcaattc tattttacca
     9841 agactatcgc aaccatgcaa aaaagcaacg gcaaatccgt tgcttttttt ggagataaga
     9901 gactattgtc ccagactctt ttctttgtat aaaattgtat agtgttattg tctatactat
     9961 tttgtagaga aagcaaaaat ccctagaaaa tgcttaggga ttcgactatt tcattaagaa
    10021 caattcaaca accatctcta tatacatgat aagggttaat aaaaatcctg tacgccagaa
    10081 gaatttgatg aatttaggat agtaaaagct gcgttttttc aaaaggaaga aaaagacgag
    10141 aataatggct aggatcgaga gggctagccc cagtctaggg aggaaattat gggtaaaggt
    10201 tttagctgta atcaggtaat attcaaatac caagaccgga aaagccaaat ccgcaaagtt
    10261 tcgtcctagt ttttttaatc taaaaagttt ggttaggata atgcagacga ctaaggtcag
    10321 tatcaataat aaaatagatg ctaatttcat taaaatcata cccatattgt atcataaaaa
    10381 aaggctaatg gaaacgagaa acagaggaat ttataggaaa gtcaggcttt tgagattgtg
    10441 ggtgattttt gttataatga aagttataaa atcttataat accttgaatg attattatcg
    10501 aaaactcttt ggagaaaaga cttttaaagt ccctattgat gcgggatttg actgtcccaa
    10561 tcgtgatgga actgtggctc atggaggctg tactttttgt acggtttcag gttctggaga
    10621 tactattgta gccccagatg cgcctatccg tgagcaattt tataaggaaa ttggctttat
    10681 gcaccgtaag tggccggatg ttcagaagta tctggtttat tttcaaaatt ttaccaacac
    10741 ccatgaaaag gtggaagtta ttcgagagcg ttatgaacag gctatcaatg agccaggtgt
    10801 ggtaggaatc aatattggaa cgcgcccaga ctgtttacca gacgaaacca tcgaatattt
    10861 ggctgagtta tcggagtgca tgcatgtgac ggttgaatta ggcttgcaga ccacttatga
    10921 agcaacctct gacctgatta accgtgtgca ttcttatgaa ttgtaggtgg aaacggtcaa
    10981 gcgtttgaga aagtatccaa aaattgagat tgtttcccca tttgatcaat ggtttgcctg
    11041 gtgaaaccca tgagatgatg gttgaaaatg tccgccgttg tgtcacggat aacgatattc
    11101 aagggattaa actgcatttg ctccatctta tgacaaatac tcgtatgcaa cgagattacc
    11161 atgagggacg tttacaattg atgagtcagg acgaatatgt cagggtcatc tgtgaccaaa
    11221 tggaaattat tcccaaacat atcgtcatcc atcgaattac aggagatgcg cctagggata
    11281 tgctgattgg gcttatgtgg agcctcaata aatgggaagc tctcaacagc attgagatgg
    11341 agatgcgacg tcgtggaagt gttcaaggat gcaaggctgt aaaacaggag tttgaaaatg
    11401 aaaagaccac ttgagatggc acatgatttt ttggctgagg tcgtgacaaa agaggatgtc
    11461 gtagtggatg cgactatggg aaatggtcat gacacgcttt ttttagccaa gctagccaag
    11521 caagtctatg cctttgatat tcagaagcaa gccttggaaa agacccaaga gcgtttgcat
    11581 caggctggct tgacaaatgc ccagttaatc ttgcaaggcc atgagacact ggaccagttt
    11641 gtgacaaaag ctaaggcagg gatttttaat ctgggctatt tgccgtcagc tgataagtct
    11701 gtcatcaccc gaccgcagac aacgattgag gcattagaaa agctatgtgg cttacttgtc
    11761 aaaggtggac gaattgctat tatgatttac tatggtcatg aaggaggcga cctcgagaga
    11821 gatgctgtct tggattttgt aatccagttg aaccaacaag agtacacagc tgccatttac
    11881 cgaactttaa atcaagtcaa caacccgccg tttttagtga tgattgaaaa attagagaga
    11941 tatagacatg gataaacaat acctacgtga aaagctggat gccatgcgcc agaattttgt
    12001 tgaatcaacc caccacgaac gagcggtggg cgtgctagac caagcgcata tgagcaaaaa
    12061 aatgcttaaa atcaagaaaa aattagttgc tcttgaaatg gaacggtgcc agagaaaaat
    12121 tgagcacaaa gactgttcca agattgacca aaaaatcaaa gagcagaagg agatatttga
    12181 atcctgttgt aaaaaagatt aaggaggacg tgcgtggaat tactgattta cctcatccta
    12241 tttttactgg tcttgattgt ctcaagtaca accaataagc tcctgccctt tttgcctctc
    12301 cctttggtgc agattctttt gggaattgtg attggtctct ttttacccaa tactgacttt
    12361 catcttaata cggagttgtt tttggccctg gttatcggac ccttgctttt ccgagaggct
    12421 gaagaagcag atgttacggc tattttaaaa cactggcgaa tcattgttta tctcatattt
    12481 ccagtgattt ttatctcgac cctgagtttg ggtggcttgg cccatcttct ttggttcagc
    12541 cttcccttgg cagcttgctt ggctgttggg gcagcccttg gtcctacgga cttggtggcc
    12601 tttgcctctc tttcggagcg ttttagcttt cctaagcgcg tgtccaatat tcttaagggc
    12661 gaaggactct tgaatgatgc ttctggtttg gtggcttttc aggtagcttt gacagcttgg
    12721 acaactggag ctttttctct ggggcaagct agcagttcgc tcatcttttc aatcctaggc
    12781 ggttttttaa ttggcttttt aacagccatg accaatcgtt tcctccatag cttcttgcta
    12841 agtgtgagag caacggatat tgctagtgag cttttattag aattgagttt gcctctagtg
    12901 accttctttc tggcagaaga agtccatgtt tcagggatta ttgccgtcgt agttgctgga
    12961 attttaaagg caagtcgctt caagaaaatc acgctcctcg aagcccaagt ggatacggtg
    13021 accgagacgg tctggcatac agtgaccttt atgctcaacg gttctgtctt tgtgatttta
    13081 gggatggagt tggaaatgat agcagaacct atcttgacca atccaatcta taatcctcta
    13141 cttttattgc tatctctcat cgcccttacc tttgtcctct ttgtcattcg ttttattatg
    13201 atctatggct attatgccta tagaacccga cgcctcaaga aaaagctaaa taagtatatg
    13261 aaggacatgt ttctcttgac cttttcaggt gttaagggaa cggtgtccat tgctacgatt
    13321 ctcttgatac caagtaatct agaacaggag tatcctctct tgcttttcct tgttgcaggt
    13381 gtgacgcttg tcagcttttt aacaggtctc ttggtcttgc ctcatctttc tgatgaagag
    13441 gaagaaagca aggattatct catgcatatc gccattttga atgaagtaac gctagagttg
    13501 gaaaaagagt tggaagacac tagaaataaa cttcccctct atgcggctat tgacaattat
    13561 catggacgta ttgaaaatct cattttaagc caagaaaacc aggatgatca agaagactgg
    13621 gctgctttga aactcttgat tcttagtatt gaaagtgatg gtttggaaca ggcctatgaa
    13681 gaggggaaca ttagcaatcg tgcttaccga gtttaccaac gttatctgaa aaatatagaa
    13741 caaggaatca atcgtaaact tgcctcaaga ctgacctatt attttcttgt ttccttgagg
    13801 attttacgtt ttctccttca tgaagttttt actctcggaa agaccttccg tagctggaag
    13861 aacaaggagc aaagccgtct ccgtgctctt gattatgacc aaattgcaga gctctatctt
    13921 gccaatacag agatgattat tgaaagtttg gaaaacctga agggagtcta cagacgctct
    13981 ttgattagtt ttatgcagga gtctcgtctt cgagaaacag ctattatcag cagtggtgcc
    14041 tttgtcgaac gggttatcaa tcgtgtcaaa cccaacaata tcgatgaaat gctgagaggc
    14101 tattatctgg agcgcaagtt gattttcgaa tacgaagaaa aacgattaat tacaactaag
    14161 tatgccaaga aattacgaca aaatgtaaat aacttagaga actattcctt gaaggaagct
    14221 gccaataccc tgccgtatga tatggtggaa ttggtaagaa gaaattagtt aatactcttc
    14281 gaaaatctct tcaaaccacg tcagcgtcgc cttggattat atatgtgact gacttcgtca
    14341 gtttcatcta caacctcaaa gcagggcttt gagcaacctg cggctagctt cctagtttgc
    14401 tctttgattt tcattgagta taagattata aatgaaggag tatgacatga aaaagtggtg
    14461 gaaagagctg atagacaaac ctttattaaa agcttttttg cattattatc aagcatcaga
    14521 tagtgagttg accagtgtcg cagtagccta ctattggttg atttcgattt tccccctgct
    14581 tttggtggtg gtcaatatcc tcccctattt tcagattcct gtgggagaat ttctgtgctt
    14641 tatgaaagac gttctgcccc caagcctcta tgaaggtgtg gaaaaaatag ccagagaagt
    14701 tttgacgcaa ccttcaacag gtttattgag tttttctgtt ttatcggcgt tatggagttt
    14761 ttcaaaatct atgaatttct tgcaaaaagc ttttaacaag gcttatggcg tcgaaaagag
    14821 tcgtggactt atttcccatc agatgctaag tctcctagtc agttttggct tgcagctcct
    14881 ctttgcgttt gccttgtttt tgatcttatt tggtcagatg attttggctt tacttgctca
    14941 ttattggaca aaagatggca ttatctatca ggctttacaa gggttggcag gtcctctgat
    15001 ttacgccctc ctctttgcta tcttggtcat gctttattat tttcttccca atatatctaa
    15061 caggaaaatt agctataccc taccaggcag tgcctttgtt ctcttagtga ttttaggttt
    15121 actaactctg ttctctagtt atctcaatta ctatgtccat catttggtgg atgtccgaat
    15181 tttaggttcc gttcttcttg ttgttatgat gttttggttt atcttgattg ctaaaattgt
    15241 tatcctaggc gcggttatca atgccagtat gcagagtttg agagatccgg tctttaaaaa
    15301 agactaacta tttatccatt acaaaagcgc atagtatcaa aactttatag aaccttgata
    15361 ctatgcgctt ttgtgctttg acagtttttt gtatagtttt tgtccaagat ttctaaatca
    15421 tctgattaaa ttcctatttt cccctatcat tgtccctgtt ttttcgaaaa tggaaggagt
    15481 ataataaatc tatcaataaa atgataggag gaactttatg ggtcatattt tcttttttct
    15541 aagtgtcttt ttggcaggga ttctatcctt cttttctcct tgtatcttac ctttgttacc
    15601 ggtctataca ggagtgttac tagatgataa ggatggtgct caggcttcta gcggcaaatt
    15661 ttcaatctca gttactagtt tattacgaac tctggccttt atagcaggaa tttcctttat
    15721 atttattttg ttgggctatg gagctggttt tttaggcgat ttgctttatg cttcttggtt
    15781 ccaatatctt actggggcaa ttattatcct tcttggtttg caccaaatgg agattctaca
    15841 ctttaagggg ctttataagg aaaagaggct acaactgcaa ggacaggggc aaaatggtaa
    15901 gggctatagt caggcatttt tattgggctt gacctttagt tttgcttgga cgccttgcgt
    15961 ggggccggtt ctggggtctg ttttggcctt ggcggcttca ggtggttcag gagcttggca
    16021 gggagctggt ctcatgttgg tgtatacgct gggcttggcg ctaccattct tgcttctagc
    16081 tctgacctct agttatgttt tgaaacattt ccgaaaactt catccctatc tcggaatcct
    16141 caaaaaagtg ggtggttttc tcattattgt gatgggactc ttggttctgt ttggaaatgc
    16201 ttcaatttta agtcaattat ttgaataaaa tggaaaggaa tatcaatatg aaaaaatggc
    16261 aaacatgtgt tcttggagca ggttcgctcc tttgtttgac ggcttgttca ggcaagtccg
    16321 tgactagtga acaccaaacg aaagatgaaa tgaagacgga gcagacagct agtaaaacaa
    16381 gcgcagctaa agggaaagag gtggctgatt ttgaattgat gggagtagat ggcaagacct
    16441 accgtttatc tgattacaag ggcaagaaag tctatctcaa attctgggct tcttggtgtt
    16501 ccatctgtct ggctagtctt ccagatacgg atgagattgc taaagaagct ggtgatgact
    16561 atgtggtctt gacagtagtg tcaccaggac ataagggaga gcaatctgaa gcggacttta
    16621 agaattggta taagggattg gattataaaa atctcccagt cctagttgac ccatcaggca
    16681 aacttttgga aacttatggt gtccgttctt acccaaccca agcctttata gacaaagaag
    16741 gcaagctggt caaaacacat ccaggattca tggaaaaaga tgcaattttg caaactttga
    16801 aggaattagc ctaggaggtg tcttatgaat gataagttaa aaatcttctt gttgctagga
    16861 gtattttttc tagccataac cggtttctat gttctattga tacgaaatgc agggcagaca
    16921 gatgcctcgc aaattgaaaa ggcggcagtt agccaaggag gaaaagcagt gaaaaaaaca
    16981 gaaattagtg aagacgcaga cttgcacgaa atttatctag ctggaggttg tttctgggga
    17041 gtggaggaat atttctcacg cgttcccggg gtgacggatg ccgtttcagg ctatgcaaat
    17101 ggtagaggag aaacaaccaa gtacgaatta attaaccaaa caggtcatgc agaaaccgtc
    17161 catgtcacct atgatgccaa gcaaatttct ctcaaggaaa tcctgcttca ctatttccgc
    17221 attatcaatc caaccagcaa aaataaacaa ggaaatgatg tggggaccca gtaccgtact
    17281 ggtgtttatt acacagatga caaggatttg gaagtgatta accaagtctt tgatgaggtg
    17341 gctaagaaat acgatcaacc tctagcagtt gaaaaggaaa acttgaagaa ttttgtggtg
    17401 gctgaggatt accatcaaga ctatctcaag aaaaatccaa atggctactg ccatatcaat
    17461 gttaatcagg cggcctatcc tgtcattgat gccagcaaat atccaaaacc aagtgatgag
    17521 gaattgaaaa agaccctgtc acctgaggag tatgcagtta cccaggaaaa tcaaacagaa
    17581 cgagctttct caaaccgtta ctgggataaa tttgaatccg gtatctatgt ggatatagca
    17641 actggggaac ctctcttttc atcaaaagac aaatttgagt ctggttgtgg ctggcctagt
    17701 tttacccaac ccatcagtcc agatgttgtc acctacaagg aagataagtc ctacaatatg
    17761 acgcgtatgg aagtgcggag ccgagtagga gattctcacc ttgggcatgt ctttacggat
    17821 ggtccacagg acaagggcgg cttacgttac tgtatcaata gcctctctat ccgctttatt
    17881 cccaaagacc aaatggaaga aaaaggctac gcttatttac tagattatgt tgattaatac
    17941 tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac cgtatgtagg gtt
//
LOCUS       DAVHSY010000038        17528 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.039, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000038 DAVHSY010000000
VERSION     DAVHSY010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17528
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.039"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..186
                     /locus_tag="VVR43_001600"
     CDS             <1..186
                     /locus_tag="VVR43_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU6149937.1"
                     /translation="EDAKNKKSYDRLAICYVRIGICRDNAKLIQKGFSLLELTEETSM
                     LSHLKKEVETHYQPKKL"
     gene            complement(476..946)
                     /locus_tag="VVR43_001601"
     CDS             complement(476..946)
                     /locus_tag="VVR43_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEU6149938.1"
                     /translation="MRMPLKRPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVAVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQTGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(912..1718)
                     /locus_tag="VVR43_001602"
     CDS             complement(912..1718)
                     /locus_tag="VVR43_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU6149939.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(1925..2566)
                     /locus_tag="VVR43_001603"
     CDS             complement(1925..2566)
                     /locus_tag="VVR43_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149940.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(2563..4671)
                     /locus_tag="VVR43_001604"
     CDS             complement(2563..4671)
                     /locus_tag="VVR43_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6149941.1"
                     /translation="MKKISHLCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(4726..5019)
                     /locus_tag="VVR43_001605"
     CDS             complement(4726..5019)
                     /locus_tag="VVR43_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU6149942.1"
                     /translation="MIGEINHEKIGVASLMVCSILASTSVLAVWVDGGQWNYGVGWSG
                     NFGYSDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            5426..5746
                     /locus_tag="VVR43_001606"
     CDS             5426..5746
                     /locus_tag="VVR43_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU6149943.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLVICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(5798..6385)
                     /locus_tag="VVR43_001607"
     CDS             complement(5798..6385)
                     /locus_tag="VVR43_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU6149944.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            6627..7298
                     /gene="sdaAB"
                     /locus_tag="VVR43_001608"
     CDS             6627..7298
                     /gene="sdaAB"
                     /locus_tag="VVR43_001608"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU6149945.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            7307..8179
                     /gene="sdaAA"
                     /locus_tag="VVR43_001609"
     CDS             7307..8179
                     /gene="sdaAA"
                     /locus_tag="VVR43_001609"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU6149946.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            8201..8833
                     /locus_tag="VVR43_001610"
     CDS             8201..8833
                     /locus_tag="VVR43_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU6149947.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIVELLQELSKNYPL
                     YITTTKNTPTAQDMTKNLGIHHFFDGIYGYSPEAPHKADVIHQALQIHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLEYFQ"
     gene            8883..9287
                     /locus_tag="VVR43_001611"
     CDS             8883..9287
                     /locus_tag="VVR43_001611"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149948.1"
                     /translation="MKIKEQTRKVTAGCSKHCFKVVDGTDEVSSKHCFEVADRTDEVS
                     SKHCFEVADRTDEVSNHIYGKATLTWFEEIFEEYKSLHNKTHSTKVNKLDTMRFSFLF
                     NVGCLISKGDNSLLQLISTESAELSNLLIDGF"
     gene            complement(9183..11033)
                     /locus_tag="VVR43_001612"
     CDS             complement(9183..11033)
                     /locus_tag="VVR43_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU6149949.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(11075..12232)
                     /locus_tag="VVR43_001613"
     CDS             complement(11075..12232)
                     /locus_tag="VVR43_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6149950.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            12290..13456
                     /locus_tag="VVR43_001614"
     CDS             12290..13456
                     /locus_tag="VVR43_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU6149951.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            13595..13921
                     /locus_tag="VVR43_001615"
     CDS             13595..13921
                     /locus_tag="VVR43_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU6149952.1"
                     /translation="MYFPTSSALIEFLILAVLEKGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            13908..14501
                     /locus_tag="VVR43_001616"
     CDS             13908..14501
                     /locus_tag="VVR43_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU6149953.1"
                     /translation="MTRTEYLTQLELYLKKLPEADQIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHVALLALLAAPIGIPLGIAILV
                     SLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGDQHA"
     gene            14494..15405
                     /locus_tag="VVR43_001617"
     CDS             14494..15405
                     /locus_tag="VVR43_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEU6149954.1"
                     /translation="MRKLTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLAMSKEPVY
                     DSRMEELTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSESPFISSGIDGILHIVSSSSNRFNDVIIGLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNGYILRIEGSRIKNSKLTTPNIVNIFDTDLTDSQLESTEHHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDVSSNYGSIFQFTREEPESRGTELSNPYK
                     TEKTDVKDQLIARSDDDIELISTPSRR"
     gene            15468..16532
                     /locus_tag="VVR43_001618"
     CDS             15468..16532
                     /locus_tag="VVR43_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149955.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEERIADLDTPIEK
                     NTQVEEEVSQAEVELESQQEEKMETPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEALK
                     SPTSKLETSSTHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIATINSHFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIYQEKDWTLEKILQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFSALLCVISIGIILLASLHIITRPSQASEADSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGNYLRILAFL"
     gene            complement(16769..16966)
                     /locus_tag="VVR43_001619"
     CDS             complement(16769..16966)
                     /locus_tag="VVR43_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide ABC transporter ATP-binding protein"
                     /protein_id="HEU6149956.1"
                     /translation="MRSLSQEKDIYSFDEPTGNLDRNSTELFLNEVEKLVNEEKIVIV
                     VTHDKDVIARASKVINMDEFH"
BASE COUNT         5373 a         3838 c         3045 g         5272 t
ORIGIN      
        1 gaggacgcca agaataagaa aagctacgat aggcttgcta tctgctatgt tcgtattggg
       61 atttgtaggg ataatgctaa acttatccaa aaaggtttct cactcctaga gctgaccgag
      121 gaaacttcta tgctgtctca tctcaaaaaa gaagtagaga cccattatca accaaagaaa
      181 ttataaaaaa agtcgaggga tttcctcgac tctttacata ttatttgttc gttagttctt
      241 aataccagcc attgttaaac cagaagtttt tagctctgcc aagccacata gtgtgtttac
      301 tactatgtgt ccatgtcacc atgaatcgcc gaacgattta acgagaaagt atgactttta
      361 cgtttatccc aactcaatta tgacattttt ttcaaaagtc aatatatctc actttttcaa
      421 cgacaagaaa gaggctgcca attgaccaac ctcttattct gaacccatca ctccatcact
      481 ttttagcttc attcgctttc ttagcgactg caatctggta ttcgacttgg tcattcccct
      541 tacctgtaca accatgagca attgtagtcg ctcctgtctg atgcgctatt tcaaccaatt
      601 ttttagaaat aagagggcgg ctcaaggcag ataccaaggg gtacttttgt tcatagtagg
      661 catgtgactg gagagctact agcacataat ctgtagcaaa ttcgtcctta acatcaatga
      721 cataagattc gactgcccca accttaagag ccttatcatg gatgaaatct aagtctttcc
      781 cttcacccac atccatacaa actgcaacaa catcatagtc tttcttcagc caggtaatag
      841 caactgatgt gtctaaaccg ccagaatagg ccaaaattac tttttcttta ctcatgttct
      901 tttccttctt tctatttttc aatggacgct ttaaaggcat cctcaatgag tttgtctaat
      961 tccccagact ccttcaactt ttgaatggtt ttatcgactg cctctttcaa ttccttgcta
     1021 tcttttttca tggctaccgc ataggaatca tcttgctctt tttcaaaatt gaggtctgcg
     1081 attgctaaat caggattatt ttccacaaat cccttggcaa cgggttcttc aaaaataacg
     1141 gcatccactt gccctgattt taaatctgtg attaaattcc catttttagg cagagatacg
     1201 agggaagaat tttgtagcaa atctttcgcc atcgtctctt gaatcgaacc tttctgcgct
     1261 ccgacctttt tctgcgccaa atcgttgaca gactgataag tggctaaatc agattttttg
     1321 acaatgagtt tattttttgc agtatagtag ggagttgaaa aatcaaacac cttgctccgt
     1381 tcatctgtct tagaaacacc tgatatggca aggtcagctt ttcctgattg aacgctagcc
     1441 agtacattgt caaaactcat aggagatagt tccaattcga cacctagttc tgttgcgata
     1501 gccttggcta attcgatatc tgaacccaca atctgatttt tcccatcaac cactttttga
     1561 tattcaaatg gagcaaaatc tggattgagg gctacaacca attttccttt ggacttgatg
     1621 gcttcaattc cagccgattg attgttacta caagcaaata gtagggggag catcactaaa
     1681 ccaaacatcg tcatcaacac cttcttcatc ttattcataa taaagcctcc tttatgttta
     1741 ttctttttta ttgtataaat aatactccta tactcatcct ttgtcaagcc taaattgaaa
     1801 aaattttcaa tttgaaacaa aaaaaaccta gaaatactac ataaaatgtc attcctaggc
     1861 gtatttatgc tatttttctc tggaaaacat gagtattcag ccagtcaaaa ggagctgaat
     1921 gaactcattt tccctcgccc aattcaatga cacgatgaca ttgttgggct acataagcat
     1981 cgtgggtcac aataatgact gttttccctt ctcgattcat ctctaagaga aacttcaaga
     2041 ccaaatctct attttcagga tccagcgaac ctgtaggttc atcggctaaa atcagctggc
     2101 tgggttttaa gatggctcta gcaactgcaa ttcgttgttg ttcgccccca gacaactcgg
     2161 agaccctttg atgcaaagta gctgacaaac ctactctctc taaaatctct tccacctttt
     2221 tgagcttgtc tttcttaggc aatttcacat atttcagcgc cagcatgaga ttgtactcga
     2281 ccgtttcatc atcaatcagg gcaaaatttt gaaacagata agagatatgt tcacggatta
     2341 ttgtttgcga cttagcagaa ttaaccgcta gatttgtctg accaaaaatc tcataccgtc
     2401 cgctataatc accatctatc aaacccaata aatttaacaa ggtcgacttc ccactaccac
     2461 tcttaccaac aatagctacc aaatccccct gatcaatcct gagagataag ttatccaaaa
     2521 tcacttttcc cccaatggtt ttggtaatat ttttcaactc aatcataaga tgcccccttt
     2581 caataactct actagacttc ttttctccat cctagaagct aagcctagca caaatagtat
     2641 atccagacat gtaaaacctg caaacagtag aagtggtaag aacgcatggg caaagaaaat
     2701 caagactaga agagggaaac tatagcccag caagagcaga acgaggagag gacggtagcg
     2761 atcgaccagt ttccacccca taaacttctt ggtaatgata tccctgcgct tcaataagaa
     2821 agttgttact agtaagaagt aggaaatcat catgctaagg agaccaaaca aagcaaagag
     2881 taggttaaaa ttccgaacag catctcgata agaatccact ttctcttgtt gaatggcttg
     2941 aatagatgaa aattttaaat aatttccatc tgacaatttc tcaactaact ctgtaatctc
     3001 tttttgatgt tgaaccgtat tttcaatttt aatcggatta tttaagccag ttgttgacag
     3061 ggaggctttc tcatcccaca tcatatcaga atcattgacc aagctaataa ttggattgga
     3121 gagattttcc tttcgcttat cactatatgg gaaaaatgac caatctcctt cataataggc
     3181 aatctcgaca tccatctcct ctatcgttcg tttttgctgc tcttcatact tcatcgaatg
     3241 aaaggcaatt aacttcccca agagctgatt tttatcttct tcacctttcg tacttgctgg
     3301 catcaaaata acttttttaa taccggtatc tggtagcttg aatcccttgc tctttagaaa
     3361 attgcgattg gcatagtaaa catccaccgt atctgttaac tgatattgct gaatctgttc
     3421 tgattggaca aaatttttta caggaagact gctactctgc acatagcccg cctgcgtttt
     3481 ttctaccaaa tcctgataaa atcgatagaa ataatccaat gccttccctg agcctgccaa
     3541 ctgctcttgc cacaagttat cattgagttg gaaagtttct aaggtcagat aatttccttg
     3601 gctgatccac tgtttctggt aatccaactc tttgttttct tgctccaaac tttttcctac
     3661 cccaactagc aagactgtca gtaaaatggt agttccaatt ttcatcaaat aattaaagag
     3721 tagaccaaat ttgaaagatg aaaaaccttt cagcagagag ctgattgtca ttttttggat
     3781 taagaggtaa gtcaaccaac tgataaagag ataaagctgc aacagcaaaa aatgagacaa
     3841 ccacagcata ggaaacaaat cttttggctt ataatcaagc aagaaaaaca cgcctagatt
     3901 gatcacaaga gccccaccta ggaggaggta aaggttgcct tttacaacat cagctaaaac
     3961 agccctatct tgaaaaccaa gtaatttttg taccccaact cgtttcatct ccatcatcgg
     4021 ttgatacact gtcactaaca caagaagcaa aatagccaag acaaaaacaa tggcagataa
     4081 aagcaaatct cgatttatga cttccactgc acttttgtag gtcggctcta gcaaggtagc
     4141 ctggtctatc ttgaaaaaat cgctccattt ctgtacaatc ctatccttgt ccatctcttg
     4201 tgtagaagtt atcgtatagc gaccatttaa actacgagat gtatccttga tataggtttg
     4261 aaaagtcata agctgaatag gtttggcttt tagaaaggtc ggaatcgtac caagtttatt
     4321 ggaaatttct ttattactat agactccttc accatctgtg gtaaaatcaa gagaagaaat
     4381 cccaaactct tggtagggga aggtatcttt atcaaaaaca ccagacttga ccacctcatc
     4441 accactgtct gttttgatga tggagacttt atactccttt gatacatcct caaaaaatcg
     4501 aagaacagac gctgcaggtt cgttaatatc tttcaaatac aaatccaaag aatctacagt
     4561 ctttcccatt tcttgaatcc gaaccacttc tcgtgtatag tttacattaa aaacaaaaaa
     4621 agtggtacac agaagcagga gtaacataca aagatgactg atttttttca tagagatacc
     4681 tcccgtgaag aaactccctc tccaaaaggg gagggagaat tttaattaaa atccatagaa
     4741 atattccatt cccgttggtg ggaatttgaa gattgaagcc cgagcccatg cctcagcttc
     4801 tgcacgatcc ttagagaatt tatttccatc tttaacagtt gctgtatgag agcgagtaga
     4861 atgtaaataa tcagaataac caaaatttcc tgaccatcct actccatagt tccattgacc
     4921 accatcaacc catactgcca aaacacttgt agaagcaagt atactacata ccattaaaga
     4981 tgcaacacca attttctcat gatttatttc tcctattatc gagagctatt ccgtagaaac
     5041 agctatagta atttgtcaac aagtatcgta gtccattgga ctcaccttcc ttctatctca
     5101 tttcattttt aaacaacgaa cttactctta actagaagaa tagttctctt ctgtatcagg
     5161 tctttgaaca accagagtag tattaatcac actctaacta ttactcaaga atcagcccaa
     5221 taaacaatat ggatagcgct ttcaaatttt taaactctta tcccatcctt ttatctatat
     5281 aataagtgaa aatataataa ctgtcaagta atcgaagtga attttataaa aaaaattaca
     5341 agccaaattt gcaaagttta caataagccg ctagggcaat cgtctatcag aatgtccgtt
     5401 tatttgtcaa taatccgaga aaatcttgca acgcttagaa gtctataaaa actatcaaca
     5461 tttatatgac ttgcgaatag caatcctgct caacctttcc acactctatc tatacaatca
     5521 agataaaaac atgtgtaagc aaatctgcta cactttacta gaggacgcca agaataagaa
     5581 aagctacgat aggctggtta tctgctatgt ccgtattggg atttgtacag acgattctaa
     5641 acttatccaa aaagggttct cccttctgga gctaaccgag gaaacttcta tgctgtctca
     5701 tctcaaaaaa gaagtagaga tctattacca agcgaaggaa agataaaaaa gccgagggat
     5761 ttcctcgact ctttacatat tatttgttcg ttagttctta ataccagcca ttgttaagcc
     5821 agaagttttt agcagcagtc catgaaccgt aacgtcctgc aacgtaggca tctgctacac
     5881 gttcttggtt ttcagctgag tagtcaccgt tcaggtatga atctgttaat tggtaacgtc
     5941 cgatataacg tccatttgta gctgtatagc taccacctga ttctttttga gcgatccatt
     6001 ctttggcttc tgcttcagat ccgcttacag ttgaaacaac tgtttcactt actactggag
     6061 tttctgctac tggagctgaa acagtttcat cttgagcggc tggtgccgca taagtagctg
     6121 gcgctggtgt tgcaacaggc gctacagggc catcgataac caactcttga ccaacataaa
     6181 tcaaatgaat gttatcaatg tggttgtttt ctgccaattt ttcaactgtt gtgttgtgag
     6241 tttcagcgat ttctgaaagt gtatcacctt ctttaacagt gtaagttgat gattcttgag
     6301 cagatacaaa tgatggagca aatactgcaa acaaggcagc tactcctgca agagttgctt
     6361 taatcttttt agttattgat ttcatattcg aaaattctcc ttctttctat agttctatca
     6421 taccctttaa atattaccgt ttcttgacac ttttatgtag aaatattaca aaattatttt
     6481 ttatttccct aaataaggtg ttttttgtca taaaagatac tatttttatg ctatttgagg
     6541 tattagaaag gttttcatcc acaattaaag ccaagcccct cattctttga tataatagag
     6601 ataagaattt ttataagggg aaactgatga aatcacttcg ttttcaatct gtctttgata
     6661 tcatcggacc agttatgatt ggcccatcta gtagccatac cgctggtgct gttcgtattg
     6721 ggaagattgt ctcttccatt tttgatgata ctccgacaga agttgaattc caacttttta
     6781 actcatttgc caagacctat cgtggtcacg gaacagacct agcccttgtt gcaggtattt
     6841 tgggaatgga tacagatgat cctgaaattc caaatagtct ggaaattgcc cacaagcgtg
     6901 gtatcaagat tgtctggacc attcagaaag acagcaatgc ccctcaccct aacaccacta
     6961 aaattactgt taaaaatgcc cacaagacca tcagcgtgac tggtatttct atcggtggag
     7021 gaaatattca ggtaaccgaa ctcaatggtt ttgccgtctc tctcaatatg aatacaccga
     7081 ctatcatcat cgttcatcaa gatattccag gtatgattgc ccttgttaca gaggcgcttt
     7141 cccgctatgg tatcaatatc gcccagatga atgtcactcg tgaaaaagct ggtgaaaaag
     7201 ccattatgat tatcgaagtt gacagtcgca actgtgatga ggctatcgaa gaaattcgaa
     7261 aaatccctca tctccacaat gtcaatttct ttaaatagga ggaagcatgt tttattctat
     7321 caaagaattg gtcgagcaag cagatctaga ctttcaagga aatgtcgcag aactcatgat
     7381 tacaacagag tttgaattga ccggtcgcga acgtgaagaa gtcttccttc tcatggaacg
     7441 caatctggaa gttatgaaag cctctgtcca acttggcctc aatgaaaata aatctcgtag
     7501 tggcctgaca ggtggagatg ctgccaaatt ggatcactac atcgaaaacg gaaaaactct
     7561 gtcagattat acgattctct cggctgcccg aaatgccatc gcagtcaatg aacacaatgc
     7621 caaaatgggc ttggtctgtg ccactccaac cgctggaagt gctggctgtc tgccatccgt
     7681 tctcactgct gctattgaaa aattagacct cagccacgag caacaattgg atttcctctt
     7741 tgctgctggt gcctttggac tagtcatcgc aaacaatgcc tccatctcag gtgctgaggg
     7801 tgggtgtcaa gctgaagttg gttcagcctc tgctatgagt gctgccgcct tgactctggc
     7861 tgcaggtgga acaccttatc aggccagtca agctattgcc tttgtcatta aaaatatgct
     7921 aggcctcatc tgtgaccctg ttgcaggttt ggtcgaagtt ccctgtgtca aacgtaatgc
     7981 catgggagct agctttgctt tcatcgcagc agacatggcc ttggcaggta tcgaatctaa
     8041 aatccctgtg gatgaagtga tcgatgccat gtaccaagta ggagcaagca tgccaactgc
     8101 ctttcgtgaa acagctgaag gtggactcgc taccacccct actggtcgtc gcctccaaaa
     8161 agaaattttc ggagaataag cttatcaaat aggagaaacc atgacctcta tcacagcgat
     8221 ttttttcgat ttggatggaa ccctcgttga tagttctatc gggattcaca atgcctttac
     8281 ctataccttt aaagagctgg gggtgcctag ccctgatgcc aaaactattc gtggttttat
     8341 gggaccacct ctcgaaagta gttttgcgac ctgcctgtcc aaagaccaaa tttctgaagc
     8401 cgtgcagata tatcgttctt actataaggc aaaaggcatc tatgaagctc aactctttcc
     8461 tcagattgta gaattacttc aagaactatc caagaattac cctctctaca tcaccactac
     8521 aaagaataca cctaccgctc aagacatgac aaaaaacttg ggaatccatc atttctttga
     8581 tggcatttat ggttacagcc ctgaagcacc ccataaggca gatgtcattc accaagcctt
     8641 gcagatacat caactagcac cagaacaagc catcatcatc ggagatacca agtttgatat
     8701 gctgggagct cgagaaacag gtattcagaa attggccatc acttggggat ttggagagca
     8761 agcagatcta ctaaactatc aacctgatta tatcgctcac aaacccttag aagttttgga
     8821 gtattttcaa taacatagac taggcaacaa ctccatttca gaagaaaatg aagtaatact
     8881 caatgaaaat caaagagcaa accaggaaag taaccgcagg ctgctcaaaa cactgtttta
     8941 aggttgtaga tggaactgac gaagtcagct caaaacactg ttttgaggtg gcagatagaa
     9001 ctgacgaagt cagctcaaaa cactgttttg aggtggcaga tagaactgac gaagtcagta
     9061 accatatcta cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtataagt
     9121 ctctacataa taaaacgcat agtaccaagg ttaacaaact tgatactatg cgtttttctt
     9181 ttttattcaa tgtgggttgt ttgattagca aaggcgataa tagcttgctt caactcatct
     9241 ccactgagag tgcggaactc tccaatcttt tgattgatgg attctaaagg catgacatta
     9301 accttaccaa cgaaaatctt atccataact tgattgtcaa cgagttcggt tgataccaag
     9361 agttcttcgt agagtttttc acctgggcgg attccaactt caacgattgg aatttcactt
     9421 tcagtgtggc cacttagaag caccatcttc ttggccaagt cataaatctt gactggtttg
     9481 cccatatcaa ggataaagac ttccccatct ttggcataag caccagcatg gataaccaga
     9541 cggctagctt ctggaatggt cataaagtaa cgggtcatgc ggaagtctgt caccgttaca
     9601 ggcccacctt cagcaatctg acgttcaaag actggaatga cactaccacg gctaccaaga
     9661 acattcccaa aacgaactgc acagtaggtt gattggctac gttggttaaa gccagtgaca
     9721 atcaactccg ccacgcgctt ggttgctccc ataacatttg gtggattgac tgccttatct
     9781 gtcgaaatca taaccatctt agacacttta gcttcatcaa cagccttagc aacattgtaa
     9841 gttccacgga tattgttttt gaaggcttct tttggattgc gctccatcat aggaacatgc
     9901 ttgtgggctg ccgcatgata aacaatagca ggtttgtact gctcaaagac ttgcaacaaa
     9961 cgatcatagt cttgaatgtc cgcaatcaca ggtacataat caatcccttg gaacttacga
    10021 atcaattcat gataaacaag gtagattgag ttttccccat gaccgagcaa gacaatgcgt
    10081 tcaggattga agcgactaac ttgacgacag atttcagaac cgattgaacc tccagctcct
    10141 gtgactaaga tggtcttacc tgtcagttct gcacccagac gcgattcgtc aagacggatt
    10201 tcctgacgac ccaaaaggtc cgtaatatca attttttgga agccagtacc tgcttggtga
    10261 aggccctgaa caacagtttc aaccttaggc atcttgtaac atttgacacc cagcttatta
    10321 cacatctgca agatacgctc atattctgac ggatccagcg acggaatcgc aacgatgaca
    10381 cgctcgattt gatggcgttt ggctaattca ggcagattgt cataagagcc caaaacagga
    10441 ataccaccaa gtttttgacc ctttttctta gaatccttat ccaaaatacc gaccagttct
    10501 aattcactgg ttggatgttg gtaactatcc ataaagagag ccccaccatc accggcacca
    10561 atcaagaagg tccgacggtg ttctccatca ccactacctt ttttgcgtct ggagtagatt
    10621 aactgccaag taatccgtgg caataaaatc aagaaggtac tcaacaagat aaagagaatg
    10681 ataaaacgga tggagaagag tggcaagaag gcataacaga tactatatga caagacactg
    10741 ctagcagtca caccaaaaaa gattttcatg aaatccgtaa tcttgctgta acgactaatg
    10801 ctcgcgttca acccccaaaa accaatcatc aattgataga acaggaaggc caaactcgta
    10861 tagataatgt agtcaacagg tgctggatta atcagcccat aaaataaaat ataagataca
    10921 atgatggaaa ccaccatact gaaaatatca aatattcccc agaaaacctg cttttgttgt
    10981 ttatttaaaa tttccaccag atcaatcaca taatctgtta gttttttatt catagaaatc
    11041 tactcctcct taaaagagtt ttactatatt gttattatag catattttta tttatttggc
    11101 ttattttatc caaataaatt attgttctct tgtactcctt cttccattta aatcctctaa
    11161 ttaaacctac aatcgtccca aagccataag caaagtgaat ggaaaataaa agaaagggca
    11221 tcacaattag aaatccattt ttatgtttta ataaagtcag caaagtgagt agtgacaaaa
    11281 gtagaaaata ggcacctaat agtaaagtta tgaatacgaa tgtgatcggt aacaatgcta
    11341 gactaaacac aagactcaaa acaaataaac aaggaacata gtgaaataat gataaacact
    11401 taaactgaac atgacttgtc aagccaatcc acaaaccatt taaatacttt tgatgcagca
    11461 ttttcttgaa tgttggtcga atatactgat aagatagaat acttgggcta tagcggattt
    11521 tataaccata ttctcgaatt ctataatgaa tatcattatc ttcagttcgg ccaagttgct
    11581 catttactaa accaaccttc tggaaaacct ctcgtttata cattccatga aaaatagaag
    11641 aaacatatct atcctcagaa ctatttcgat aattggcaat gctactgcca aacatatttt
    11701 cctcaacaag atgcaaggtc tctgcccatt ttccttttcc ttcgacaatc gtcggtctag
    11761 gccccccaca gacaaattca ccttgttgaa taatagccac attgttcatt acaaaagtct
    11821 cagtaacttt tgaatgagca tcaattttta aaataaggtc ccctacagaa tgtttaactc
    11881 ccaggttaaa accactagct tgatttttct taggattgtt atacaatcta attgagttaa
    11941 actctgtatc ttcctttata aattgctgaa tgatagctgt ggtcccatct gtggacatag
    12001 catttataaa tagaatttca atattctctt taggataggt ttgatttttt aagtcttcaa
    12061 ttagaccagg cagatatttt tcttcattgt atgcactgat tacaatggat acgagaagac
    12121 tttcaacatt ttgagtcact actactctcc tgaatttttc cttccaccat tctatcataa
    12181 ttttcaagac tttcccattt ttatcttgaa agccagaaac cttacttgac attatagtga
    12241 aaaagcctta aaataagctg ttattaaaat cagctagaag aggtattata tgaaaaagca
    12301 atcactcttt tttgttccag gtattatcct gattggtgtt tccttgcgaa ctccttttac
    12361 tgttttaccc attattttgg gaaatatttc gcaaggtctg gaggtagaag ttagttcgct
    12421 tggtgtcttg accagcctgc ctctccttat gtttaccctc ttttcaccat tttctaccca
    12481 actggctcag aaaatcggct tggagcatct cttcacctac agcctcttct tcttgaccat
    12541 cggctcactt attcgactaa tcaatctgcc cctgctctat ctaggaacct tgatggttgg
    12601 ggcaagtgtc gcagtcatca atgtcctgct tcctagtctt atccaagcca atcaaccaaa
    12661 gaaaattggt tttctgacca ccttatatgt aacgtctatg gggattgcaa cggctctggc
    12721 ttcctatcta gctgtgccca ttacacaagc cagttcttgg aaaggactta tcctcctcct
    12781 cacgttactc tgtctagcaa cttttttggt ctggctccca aatcaccgct ataatcatag
    12841 actagctcca caaaccaaac aaaaaagtca aataaaggtc atgcgtaata aacaggtttg
    12901 ggcaattatt atcttttcag gttttcaatc cttgatcttt tacaccgtca tgacctggtt
    12961 acctaccatg tctatccatg caggtctatc cagtcacgaa gctggcttgc tgacttctat
    13021 cttatctctg attagcattc ctttttcaat gaccatccca agcctgacaa ccagtttatc
    13081 tactcgcaac cgtcagctca tgctcactct ggtttcacta gctggtgtgg tcggcatttc
    13141 catgctcttt ttcccaatca ataatttcat ttactggctt gccatccatc tcctcatcgg
    13201 aaccgcaacc agcgccctct tcccttatct catggtcaac ttttcactca agacaagcgc
    13261 ccctgaaaag acagcccaat tgtccggcct atctcaaaca ggaggctata tcctagcagc
    13321 ctttgggcca accctctttg gttacagttt tgacctgttc cactcttggg taccatctgt
    13381 agctgccctc ttgctcatcg atatcctgat gactgtggcc ctctttacag tggacagagc
    13441 ggataagatc ctttaaactt ctagttttag ctagaagttt tttatatata aaaattttac
    13501 acatttctct tgacagggct ttcttttaga tgtacaatgt atgtgtagaa aaattatata
    13561 taaaaatcct acacattaga aaaggaggtt tcccatgtac tttccaacat cctctgcctt
    13621 gattgaattt ctcatcttgg ccgtactgga aaaaggggat tcttatggtt atgagattag
    13681 ccaaaccatt aagctgatcg ctaatatcaa agaatccaca ctctatccca ttctcaaaaa
    13741 attggaaggc aatagctttc tgacaaccta ttctagagag ttccaaggtc gcatgcgcaa
    13801 atactactcc ttgacaaatg gtggtataga acagctcttg accctaaaag atgaatgggc
    13861 actctataca gacaccatca atggcatcat agaagggagt atccgccatg acaagaactg
    13921 aatacctgac tcagctagaa ctctatctca aaaaactgcc tgaagctgac caaattgaag
    13981 ccatggacta tttcagggaa ctctttgatg atgctggagt cgaaggagag gaagaactca
    14041 tcgctagctt gggaactccc aaagaagcag cccacgaagt tctctctaat cttcttgata
    14101 aaaaaatcaa tgaagcacct gctcaaaaaa ataaccgaca aattttacat gtcgccttat
    14161 tagccctcct tgcagcaccc atcggtattc ctctgggaat cgccatcctc gtgtccctgt
    14221 tcgcaatcct tgtggcagcc ttgactgtca tcttggcttt ctttgcggtt tccatactgg
    14281 gtatcatcgg tggattccta tttttagttg aaagtttcac tgtcctagcc caagccaaat
    14341 cagcctttat cttgattttc ggttctggtt tactggctat cggtgcttct tcactagtct
    14401 tactaggtat ttcctatgta gcccgcttct tcggtctact cattgttcgc ttggtgcaat
    14461 ttgttcttaa aaaaggaaag agaggtgacc agcatgcgta aattgacaaa aggatttctc
    14521 atttttggtg tcgtgactac cgttatcggc tttatcctgc tctttgtagg tatccaatct
    14581 gacgggatta agagcctact tgccatgtcc aaggagcctg tctatgatag tcggatggaa
    14641 gagttaacct ttggcaagga agtcgaaaac ttagagatca ctcttcacca gcacgcgctg
    14701 accatcacag actctttcga tgatcaaatc cacatttctt accatccatc actttctgct
    14761 caccatgatc ttatcaccaa tcagaacgat agaactctga gtctcactga taagaaactg
    14821 tctgaaagtc catttatctc ttctggaatt gatgggattc tccatattgt aagtagttca
    14881 tctaatcgtt ttaatgatgt catcatcgga ctaccgaaag ggagaactct aaaagggatc
    14941 aacatctcag ccaatcgcgg acaaaccacc atcataaatg ctagccttga aaatgcgacc
    15001 ctcaatacaa acggctatat cctccgaatt gaaggaagtc gtatcaaaaa cagtaaactc
    15061 acaacgccca atatcgttaa tatctttgat acagatctta cagatagtca gctagagtca
    15121 acagaacatc acttccacgc tgaaaatatc caagtccatg gtaaggttga actgactgcc
    15181 aaagattatc tccgaatcat cctagaccag aaagagagcc aacgaattaa ttgggatgtc
    15241 tcaagtaact atgggtctat cttccaattc acaagagaag agcctgaatc aagaggtacg
    15301 gaattaagca acccttacaa aactgaaaaa accgatgtca aggatcaact cattgcgaga
    15361 tctgatgatg atattgagct aatatccaca ccaagcagac gttgacaaaa acgcttacat
    15421 ctgctactat ggaaacatat ttatctaact aaaaaggagg ttctaccatg aaacaagaat
    15481 ggtttgaaag taatgatttt gtaaaaacaa caagcaagaa caagcctgaa gagcaagctc
    15541 aagaggttgc agacaaggct gaagaaagga tagccgatct cgatacacca attgaaaaaa
    15601 atactcaagt agaggaggaa gtctctcagg ctgaagtcga actggaaagc cagcaagaag
    15661 agaaaatgga aactcctgaa gacagtgaag cgagaacaga aatagaagaa aagaaggcat
    15721 ctaattctac tgaagaagag ccagaccttt ctaaagaaac agaaaaagtc actatagctg
    15781 aagagagcca agaagctctt cctcagcaaa aagcaaccac gaaagagccc cttcttatca
    15841 gtaaatcttt agaaagtcct tatatccccg accaagctcc aaaatctagg gataaatgga
    15901 aagagcaagt gcttgatttt tggtcttggc tagtggaggc tctcaaatct cctacaagca
    15961 agcttgaaac aagtagcaca cacagctaca cagcctttct cttgctcatt ctgttttctg
    16021 catcttcctt tttctttagt atctaccaca tcaaacatgc ttactatgga catatagcaa
    16081 ctataaacag ccacttccct gagcaactag cacctttaac tctcttttct atcatctcta
    16141 tcctagtagc gacaacactc ttcttctttt cattcctctt gggtagtttc gtcgtgagac
    16201 gatttatcta ccaagaaaag gactggacgc tggaaaagat tctccaacaa tatagtcaac
    16261 tcttggcaat tccaatcttc ctcactgcca ttgctagttt ctttgctttc tttgacagcc
    16321 tacgattttc agccctttta tgtgtgatta gcattggaat cattctgctt gctagtctcc
    16381 atatcattac cagaccaagt caagcaagtg aagccgactc cttctatcag ttattcttgt
    16441 ctgtccttgt gaacggagtt attatcctcc tcttctttgt agctgaagtg gcactgattg
    16501 gaaattatct tcgtatcttg gcctttcttt aaacttcaat cctgtcatcc ttggcaggat
    16561 tttttctatg tcaaaaaagc aagtcgattg acctgcttct gctttacttt tcttgtgcta
    16621 atgttttaaa atcttgtcct aggatgggtt ttattcctag agttcaaagt atgatagcgt
    16681 tgctataaag ttcgttattc caaatattat gcaaactagt tatatgtaaa attaagatta
    16741 gaaaccacca atctccattt attaactttt aatgaaattc gtccatatta ataactttac
    16801 ttgctctagc aataacatcc ttgtcatgag tcacgacaat aacaatcttt tcctcgttca
    16861 ctaatttctc aacctcgttt agaaataatt cagttgagtt tctgtccaaa tttcctgtag
    16921 gctcatcgaa tgaatagata tccttttctt gcgataaact cctcatgaat agaatttttt
    16981 gtttctgacc ttacgaaata ttggtggctt tcccatcaat ctgatgactc agagctatat
    17041 tgagattcaa actatcaaga ttatttgatt catagttttc cttatcaaat agggtgaaat
    17101 taatattttt tgtcatgctt catcacctcc agatatagta ttaaaatttt agatcagttg
    17161 actatccgtg tcgaatcttt catagaaact cttgttatta tagaaataaa taacaaatta
    17221 ttagtacatg aataataaat ctgatacaat ggtgactata attgatttta tttccactaa
    17281 tctttctatc gtagagcaag ctcactgaaa gtaatattaa aaagattgat attaataatt
    17341 tcaaatagtt aattgaataa aataagttaa acaatgtcga agtacataaa cataagttta
    17401 taagtattga tacaacagat actccaagct tttttttata tccaaaataa gctgaaaaca
    17461 ttaaaataat agaataggca caaataatat aattcattta tttttcctcc aaagtcaaat
    17521 aataaatc
//
LOCUS       DAVHSY010000039        17355 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.040, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000039 DAVHSY010000000
VERSION     DAVHSY010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17355
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.040"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(44..1384)
                     /locus_tag="VVR43_001620"
     CDS             complement(44..1384)
                     /locus_tag="VVR43_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6149957.1"
                     /translation="MYIFWIILYTLITNGLEIVIFFKVDGIGLTFERIFKAFLLKILL
                     AFVFVMIGYMIGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQEQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLKDSSKKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(1397..2134)
                     /locus_tag="VVR43_001621"
     CDS             complement(1397..2134)
                     /locus_tag="VVR43_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6149958.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(2139..2477)
                     /locus_tag="VVR43_001622"
     CDS             complement(2139..2477)
                     /locus_tag="VVR43_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6149959.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVRYARRRYRE
                     IRQKWLKEGE"
     gene            2753..3082
                     /locus_tag="VVR43_001623"
     CDS             2753..3082
                     /locus_tag="VVR43_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU6149960.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKTETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(3250..4299)
                     /locus_tag="VVR43_001624"
     CDS             complement(3250..4299)
                     /locus_tag="VVR43_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6149961.1"
                     /translation="MKDLFLKRKQAFRKECLCYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWIFVQTLFLLLFAPLFLVMGYGLPVFLVYVLLLGVGKYFLFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKVVQKVSGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSLLAQVFIEQSWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLISFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(4296..5027)
                     /locus_tag="VVR43_001625"
     CDS             complement(4296..5027)
                     /locus_tag="VVR43_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149962.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            5095..5505
                     /locus_tag="VVR43_001626"
     CDS             5095..5505
                     /locus_tag="VVR43_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU6149963.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            5515..5802
                     /locus_tag="VVR43_001627"
     CDS             5515..5802
                     /locus_tag="VVR43_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149964.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            5964..6158
                     /locus_tag="VVR43_001628"
     CDS             5964..6158
                     /locus_tag="VVR43_001628"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149965.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSNHTHD
                     KPTLTWFEEIFEEYHSPFHN"
     gene            complement(6480..7616)
                     /gene="dnaJ"
                     /locus_tag="VVR43_001629"
     CDS             complement(6480..7616)
                     /gene="dnaJ"
                     /locus_tag="VVR43_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU6149966.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEVKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(7821..8174)
                     /locus_tag="VVR43_001630"
     CDS             complement(7821..8174)
                     /locus_tag="VVR43_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149967.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDYTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(8187..10010)
                     /gene="dnaK"
                     /locus_tag="VVR43_001631"
     CDS             complement(8187..10010)
                     /gene="dnaK"
                     /locus_tag="VVR43_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU6149968.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(10490..11014)
                     /gene="grpE"
                     /locus_tag="VVR43_001632"
     CDS             complement(10490..11014)
                     /gene="grpE"
                     /locus_tag="VVR43_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU6149969.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(11041..12075)
                     /gene="hrcA"
                     /locus_tag="VVR43_001633"
     CDS             complement(11041..12075)
                     /gene="hrcA"
                     /locus_tag="VVR43_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU6149970.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVHLLNFANLAAYQFFDQPQKVALEIREGLREEQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(12240..12749)
                     /locus_tag="VVR43_001634"
     CDS             complement(12240..12749)
                     /locus_tag="VVR43_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU6149971.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            13357..15690
                     /locus_tag="VVR43_001635"
     CDS             13357..15690
                     /locus_tag="VVR43_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU6149972.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQSNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            15703..17166
                     /locus_tag="VVR43_001636"
     CDS             15703..17166
                     /locus_tag="VVR43_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU6149973.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILDPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            17166..>17355
                     /locus_tag="VVR43_001637"
     CDS             17166..>17355
                     /locus_tag="VVR43_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HEU6149974.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         5455 a         3550 c         3311 g         5039 t
ORIGIN      
        1 aaataagacc gagtaacaag aactctcggt cttatttttt tcatcattct gtaggtatca
       61 tagtaagcac ctgacgaaag acttgatctt gacaggtagt atttaaactg gcattgggat
      121 aactttccac aatcttcata acggtataga gaccgacacc tctctcctcc cctttagaac
      181 taactccaaa ggagaagatt tcagaaatat ctatgccctc ttctttgatg gaattttcga
      241 tgatgaaggt ctcctgtgct ccacttttta aaaaggcaat tgaaacatga ggttgaccgg
      301 cctctgcact cgcttcaata gcattatcac aaaggataga cacaatggtt agaaaatcaa
      361 gcagtctcat cccctcaacc tgaatctctt caggaacttc gacattaaag acaatgtcct
      421 tttctctagc ttttataaat tttccagcta ggagactttt gagggcacga tcccgaacat
      481 tcaccaatcg gccaaggtca tatttattgt cctgcaattt tttactagaa tcctttaaga
      541 ccaagtcata gacctctttt atctgctcca tatcctcctc ttcaataccc agacgtaaac
      601 ttgtcaagag gttggtgtag tcatggcgaa aactccttac ttccttgtaa agttcctcta
      661 tatgccgact atagcgttcc atatctctat agcgcaagac ctgctcttgg tccagtctat
      721 catggagttt gtccttcaaa taggtatcca atttcttgat aacccccata aaaaatagga
      781 ggtaaaacac taggatgaga tggcgaacag tcgttgattg aataccttgc tcatattcaa
      841 agtaagacag actttgtatc accaaatagt aagcccccat tatccagtta atcttagtca
      901 gggacttttg aaaacctgta tctagaatct cccttctcaa actagtaaaa tcatagtcca
      961 accatttcaa aaaggctaga gaaatgaaga aattgaaaat tattatacat aacccagtaa
     1021 atgagtagcc atcatatact tgctcttgtc ccaaaaatgg aagcacaaaa taggagactc
     1081 ctctataaaa gagattcacc aatatcattg gaaagagacc ataaaagaaa aggagttttt
     1141 taggaagccc tcttaacaat aagaaagaca agcctatgcc atacaagggt tccataaaat
     1201 aagataggta aacatttcct atcatatagc caatcattac aaaaacaaag gccaacagta
     1261 tcttcaaaag aaaggcctta aaaatcctct caaaagtgag accaattcca tctaccttaa
     1321 agaaaatgac aatttctagc ccattagtaa taagtgtata caatataatc caaaaaatat
     1381 acataaattt cctagttcag tgtaagttat taatagcctc agacacttcc ctgaccttat
     1441 aacgcgcgat cagacagctt ccaccattgg gaaagaaaag gagtttttct ttcttatcca
     1501 aatgcaccac atttgcagga ttgatgagaa aagagcgatg gcactgcaag agacggggtt
     1561 cctgcttaaa aacctcctct aaactcgccg taaattctag cctgtccgtc ttggtataga
     1621 gaataacacg atggggtctt ggggatgttt cgagatagta aacctctttg aaaggatatt
     1681 ggaattgggc aaattttgat ttaaagtaaa agcaatcttc cgccagactt ttactatctt
     1741 gactattggc atagaggagg gctgtctcga tacgagattc aaactcctct gccgaaaggg
     1801 ccttatcaat gtagtccaaa gctgacactt ggtagcgaaa ggacagaggc ataaactccg
     1861 agtgagtcgt cacaaagacg attagggcat aagggtcttg ttcccgaatc tttctagcca
     1921 cttccagtcc cttcatctct tcatttcgaa tctcaatatc caaaaagaat agctgatggg
     1981 cccccttctc atgcacctct gccagcagtt ggtccggctt gccaaatacc tcaaaagagc
     2041 taggaatgat atgatgtgct ttcaaaagtt tctcaatcgt cgtttcaatt ctagtctgtt
     2101 gggaaaaatc atcttctaaa acaaatattc tcatcttctt actctccctc tttcaaccat
     2161 ttttgacgta tttctctata gcgacgtctg gcatacctga cagcatattg accttcttct
     2221 ccgagaaaaa ggattctttc ttgaaaatca atcgatttta atttatcaag attaaccaaa
     2281 caatttcgat gacatctcat caaagtttcc ccacattggt tctcaagatt acttaaattt
     2341 tgaagcatat taaaactagc tttttctgta acaatctgta cggtatgggc tttagttgga
     2401 tgtgtttgga tatagtagat atcgtcgatg tttactttat agactgtttt ctgtgtctga
     2461 ataatcatat gtttcattgg attctcctcc taagaaaaga ataacagaaa agatctagcc
     2521 caagcacacc caatcctaaa cagtctttga aaactcctaa aaggattatt ttctacaaca
     2581 tcatgatgag cttacaacta ttttatcata aaattcactc agcgcaattc aagacatttc
     2641 aatgacaatt aaagatttga ataaaaaaaa agaattaaaa gtgataaact aacagtatca
     2701 aaacacagtt gccagaagta agactggcac ccagattaaa ggaggcattc ccatgacaga
     2761 tacagacccc atcaaaagag ctcatacttt gattactgac ttaaacaaag cctaccaagc
     2821 atgcaaacag gcaagcgctg acgacgtccg ctttcaggag caattaaact ctattcttgg
     2881 ttttctagcc aagactgaaa cagtggataa tcgattcttg attgaactag aaaaatttta
     2941 ccagacttcc agtcttctca tgggactcag cgctcttgat ccagatgctc caactcgcgc
     3001 cgcttggcgg gcctatgacc gcttccactt tgaccaagtc aagaccaagt taatactcaa
     3061 tgagaatcaa agagcaaact aggaagctag ccgcaagctg tacttgagta cggtaaggcg
     3121 acgctgacgt ggtttgaaga gattttcgaa gagtataagt ctctacggac caaccattat
     3181 cctgtagtaa caaaaaagaa gctgagacaa actgaactca acttcttttt tagtgtcgta
     3241 tcagcaatgt tagtcctgca tctgacgttt tacctgataa ggcaaataca agactagtaa
     3301 aaccaaacca gctcctagta aggctagaag ggctagtttt tcttggaagg taatcaaccc
     3361 aacaactaat tccacaagta aaacaaaact gatcaatcct cgaactacct cctgtaagcc
     3421 tttttccttt tgccccttgt ccagcggaaa gagttgggtc aaatactggt agtcaaaggc
     3481 atgatagagg gccagcaact ggaaaagcaa gaggtagtta aagagaacta ccactgctgt
     3541 cgcaatccaa gattgctcga taaagacctg cgccagcaaa gaaagcaaga gcagacggag
     3601 actaagggca aaaaggtctc catttcgcaa ataagaacgc agatagagat tttgccaaat
     3661 cttcccagac accttctgaa caacctttag aataaagtcc agataggcac gacgcttgac
     3721 gctgtttgaa attcccttga cctgcgtaaa gagggcaaag aaacgaagca agacttgctt
     3781 acgcttgctt tcttgggaaa tgacatagtc ccaatccagt ccagtttcag tgaaaaattt
     3841 gctggccttt tgacgaaaga ggaaatattt tcctaccccc aataaaagca catagaccag
     3901 aaaaacaggc aagccataac ccatgactaa aaacaagggc gcaaataaca gcaagaagag
     3961 ggtctgaaca aaaatccaaa agactaggga aatgccggtt tgacgcttga gatggagctt
     4021 gatttcctct tctccaacta agagaaagag cttgtctgga gcctccatat aggtggcaat
     4081 tcctccccaa agtaaaagta aaacagacgt aattcctaca aacaaaagga taggccaatg
     4141 attttcagga aaatgttgta agagttgact gtactggtag gctagaaagc ccaacaggac
     4201 aagcaggaac aagacaaagt ggtcattgag cacatagcgc agataacaaa gacactcctt
     4261 acgaaaggcc tgctttctct ttaaaaacaa gtctttcata gatcctcctc tttggtcaga
     4321 gccaagtaaa tatcattcaa actagcctca ggcatatcaa aggcttcacg tagttgcagg
     4381 agattgcctt tggcacgcac ctctcccttg tgaagaatga caaaggcatc acacatcttt
     4441 tccgccgaat ccagcacgtg ggtactcatg agaatagact tgcccttttg cttctccact
     4501 tccaaaagct gaatcaaatc agaaatagcc agcggatcaa gaccaaggaa aggctcatcc
     4561 acgatgaaaa gacttggatc caccacaaaa gcacagataa tcatgacctt ctgcttcatc
     4621 ccttttgaaa aatgaacagg gaaccagtct aatttctgtt ccaaacggaa catttttaac
     4681 aagggctcta ctcgttcgaa agccactttt tgctcaatac cgtaagccat agcaaccgtt
     4741 tcgatatgct ctctgagggt caattcctca tacagactag gcgtctcagg aatgtagcca
     4801 atctgcttgc ggtagctagt cgcatctcct tgcagagtca ggccattgat attgatggag
     4861 ccactataag gtgccaacag accgataatc tcattgatcg tcgttgattt cccagcacca
     4921 ttgagaccaa tcaaaccgac caactgccca ctttcaacag taaaggacac atctttcaaa
     4981 acaggaacat gaacatagcc acctgtcagg tttttaattt ctaacatatt ttctccaaat
     5041 ctggtataat gtagctatat tatatcaaaa ttcagtacag tagaggtaga ttttatgtca
     5101 gattgcattt tttgtaaaat catcgcaggg gaaattcctg cttcaaaagt atatgaagat
     5161 gagcaggtcc ttgcctttct tgatatctct caagtaacac taggacacac cttggtcgtg
     5221 ccaaaagaac actatcgcaa tcttttggag atggatgcta cgagcgccag ccaactcttt
     5281 gcccaagtac caaaagtagc tcaaaaagtc atgaaagtca ctaaggctgc tggtatgaat
     5341 atcatttcca actgtgaaga agtcgctggt caaacagttt ttcatactca cgttcacctt
     5401 gtgcctcgct acagtgctga cgatgacctc aagattgatt ttatcgccca cgaaccagac
     5461 tttgacaaac ttgctcaagt cgctgaaacc atcaaaaacg cttaaggagt tgctatgaaa
     5521 ttatccaacc tactgctatt tgcaggagct gcagccggaa gttatctggt tacaaaaaat
     5581 cgccaaacca tcacagatga agtcttgaat accactgacc gcgttcaagc tatcaaggac
     5641 gatgtggata ttatccaaaa cagcctgcaa atcattaacc agcaaaaaga acttatcaag
     5701 gaataccaag aagacttgac ttacaagttt aaggtcttgg aaaaggatat ccagactaga
     5761 ctagctgtga taaaagaaat gcagggaact gaagataagt aaaaagagcc cgacggctct
     5821 tttttaaaac gtaaacaagt tatagtgaat tgaatttaga atagcacatc atagtttcta
     5881 aagcattgtt agagattact ttaaaatcct cttatcaatt tgttcatatt ctatttcaat
     5941 ctactatata tatcccatca actatgcatc ataatttagg taactcatac tcaataaaaa
     6001 tcaaaaagca aactagaaag ctaggcacag actgctcaaa acaccgtttt aaggttgtgg
     6061 atagaactga cgaagtcagt aaccataccc atgacaagcc gacgctgacg tggtttgaag
     6121 aaatttttga agagtatcat tcaccatttc acaactaaat cgaagacttt ctgccgtaat
     6181 gaaaacacct gaaacagctt ggtttcagct gtccggaaac tttaagactt aggttcaaag
     6241 tttaggtatg gaacttcgaa ggaggtcgct accgtccgtc attacttagg aaagtcttaa
     6301 aaaatctata aagtaaaaag agcccgacag ctctttttgt ttatactcaa tgaaaatcaa
     6361 aaagcaaact aggaaactag ccacgggctg ctcaaaacac tgttttgagg ttgtagatac
     6421 gactcacata tatacggcaa ggcaacgctg acgtggtttg aagagatttt cgaagagtat
     6481 tattctccat caaaggcatc ttttatatgg tcaaagaagc cttttttctt tggatttact
     6541 ttcaagtcac cagcagtcgc gaattctttc aaggctactt tttggcggtc gttcaagcct
     6601 gtcggtgtta cgacattaac agtaacgtat tggtcaccaa ctgcaccgcc acgaaggctc
     6661 ggtgccccct tactacgtag gcggaatttc ttaccagtct gagttccctc tggaataacc
     6721 aattcaacat caccgtgaac agttggaata tctactgtat caccaagagc cgcttggaca
     6781 aagttgaggt tgagattgta gaagatagtc gttccttcac gttcaaactt gtcgctagct
     6841 tctacagaaa ctactacata caagtcacca taaggtccac cgttaaagcc tgcttcacct
     6901 tgaccagcga ggcgaatttg ttgacctgtt tccacaccag cagggatttt cacatgtacg
     6961 ctatgagctt gtttctcatg acctgttcca tgacaggttg tacatggata tttgacttct
     7021 tttcctcgac cgtgacagac atcacaggtt acttggcgac gcatcatacc aagaggagtc
     7081 tgcgtatcga cgttaatgac accagcgcca tgacagcgtc cacaagtgac tggacttgtc
     7141 cctggcttag caccagagcc attacatgta cgacagccag cttcacgatg atacttaact
     7201 tccttctcag ttccgaagat agcttcttca aatgtcaaat tgacacgata ctggagatca
     7261 tctccttggc gaggagcgtt tggattgcgc gaagaaccgc ctccgccgaa gaaacttgag
     7321 aaaatatcct caaaaccacc gaagccacct gccccattga aaccaccgaa accaccagct
     7381 ccaccaaaac caccattggc gcctgcagca ccatactggt cataggcagc acgtttttgg
     7441 tcgtcactca aagtctcata ggcttcttga acttccttgt acttgtcctc agcaccaggc
     7501 tccttgttga tatctgggtg atattttttg gaaagcttac gataagcctt tttgatctcg
     7561 tctgccgaag cgttttttga cacccccaga cgatcataaa attcagtatt gttcatacaa
     7621 gataccaaga ccgtaaaatt cgactgaaaa ataggaaatc tgacgctgga gcgacgctcc
     7681 tagacagatt tctctttttt ccgagaattt aggtcgggtt caattccttt cttttatatt
     7741 gatgagataa tactccagcc actcggccct atcccttttt accgaaaaac agaggctggg
     7801 ttgcaacctc tgtggttaga ttattcattt gaaataaaaa tggttgtatt atctctagta
     7861 gtaatcttca aagacctttt agctaaatca aactcaaatt tattatagtg tgggtcttgt
     7921 gttttatata ggtgtaactc ctgacatata tgatccgaaa agtaaatcat aacatcttta
     7981 aacacagaag tgtagtcata tttactctta ccaacagcta cttctgtaaa ttctttataa
     8041 atgacatttc catttctttc cacagtcacc agcatttctg ttggattata atccaaatta
     8101 aataattctt caaaaaactt tatcttttca tgataatctg caatgtcaga aagattattt
     8161 ttattaacac tcataacact agccccttat ttttcagtaa actctccgtc tacgacgtca
     8221 tcgcctgcgt ttcctgttgc ttgtgcgcct tctgctcctt cttgagcttg ttgcgctgct
     8281 gcggcttgtt cgtagagttt cacagcaagg ccttgagctt tttcgttcaa cgcttcaagt
     8341 ttcgctttca tgtcgtccaa gttgttgtct tcttgagctt tcttaaggtc atcaagggca
     8401 gcttgggcag cgtcacgttc tgcgtcgaag cctttacctt cagtttcctt gattgtcttt
     8461 tcagtcgcaa agattgcttg gtctacttca ttacgaaggt ctacttcttc tttacgtttc
     8521 ttatcagctt cagcgtttgc ttcggcatct ttcatcatgc ggtcgatttc ttcgtcagtc
     8581 aaacctgagt tcgattggat gacaatagtt tgttcttttt gagttccaag gtctttggcc
     8641 ttaacagaca cgataccgtt cttgtcgatg tcaaatgtta cttcgatttg aggaattcca
     8701 cgaggtgcag ctgggatatc agtcaattgg aagcgtccaa gagtcttgtt atctgctgcc
     8761 attgggcgtt caccttgaag aacgtggata tcaacggctg gttggttgtc tgctgctgtt
     8821 gagaagactt gtgatttaga tgttgggatt gtagtgttgc gatcgataag ttttgtaaat
     8881 actccaccca ttgtttcgat accaagtgac aatggcgtta catcaagaag gacaacgtcc
     8941 ttgacatcac cagtaatcac accaccttgg atagccgcac ccatagcaac tacttcatca
     9001 gggtttactg atttgtttgg ttctttacca gtttcagctt taacagcttc aacaacggca
     9061 gggatacgag ttgaaccacc aacaaggata acttcgtcga tttctgacaa gctcaaacct
     9121 gcatctgaaa gggcttgacg aactggaact tttgtacgtt caacaaggtc acgagtcaaa
     9181 tcgtcaaatt tcgcacgagt caaagtcatt tccaagtgaa gaggtccagc ctcacctgca
     9241 gtgataaatg gcaagctgat ttgtgttgaa gttacaccag aaaggtcttt cttcgctttt
     9301 tcagccgcat ctttcaaacg ttgcattgcc atcttgtcag tagacaagtc gataccgttt
     9361 tctttcttga attctgctac caagtggtca atgatttttt ggtcaaagtc gtcaccacca
     9421 agtttgttgt cccctgcagt tgacaatacg tcgaagacac cgtcacccaa ttcaaggata
     9481 gagacgtcga atgtaccacc accaaggtca aataccaaga ttttttcttc tttgtcagtc
     9541 ttgtccaaac cataagcaag agctgctgca gttggttcgt taacaatacg ttctacttca
     9601 agaccagcaa ttttaccagc gtcttttgtt gcttgacgtt gagcgtcgtt gaagtaagcc
     9661 ggaactgtga taacagcttt ggttactttc tcaccaaggt agtcttcagc gtagcctttc
     9721 aagtattgaa ggatcatagc tgagatttct tgtggagtgt attcttttcc atttgcagaa
     9781 actttttcag aagttcccat cttagatttg atagagataa ctgtatctgg gtttgtgact
     9841 gcttgacgtt ttgcagcatc accaacgata atttctccgt ttttgaatga gactacagat
     9901 ggagttgtgc ggtttccttc tgggtttgcg atgattttgc tttcagttcc ttcaagaact
     9961 gcaactgctg agtttgttgt acctaagtca ataccgataa ttttagacat gtgtttttct
    10021 ccttgttagt taattttcta tttttctttt tgatactctt cttaagtggc gacgccgtca
    10081 gagcttgact ttgtcaatat ctttgactaa actttgagcc taaggtctca aaatttgcgc
    10141 aaatagcgcc acagcgaaga gtatcgtctt tggttcgctt cgctcactat tacaaagcca
    10201 aacatatttt atctttcttc atagtttatt gtcgtttcgg acaagttttc tattctgtaa
    10261 attgcgacac gaggagtcga aatcgatttt atttcgacga cgagttagta aggaagctag
    10321 acaaacgcca tagcgattgc cgttttctga cgagttgctt tagctaccgt cagaattgcc
    10381 gaatcgaaca cgccctaagc tctgagtaaa aaagatagat tttcttgtgt tcatcgaaca
    10441 cttcgtcaat ctcctatttt tactgcgagc tttttacggg ctttgtatct tagttataca
    10501 ccactaccat tgctgggcgt aggatgcggt catggagttt gtagcctttt tgaaagactt
    10561 gggcgatggt atctactggg tgttcatcgt ctgctgggag agtttggatg gccatatggt
    10621 agttatggtc aaattcgcca tctgctgcga tttcttcaat tccttcttct ttcaaagcgt
    10681 gaatcaagct ttcttgcacc atccccaagc ccttcttcac atcatctgtc aaaccttcaa
    10741 ctgcaagtgc acgctcaagg ttgtcaagag atggtaagat tgcttttgcc aagtcctggc
    10801 tacgataacg ttgcaagttt tgacgttctt cattggcacg gcgttggata ttttgcattt
    10861 ctgcatgagc gcgaagatat ttgttttcga actcatctgc acgttcattt gccaagtcca
    10921 actcagactt ttcaggagtt gtttcttcag ctgtttccac aacttcctct tcttgaactt
    10981 cttctacttc ttcatttttt atatcttggg ccatgttcgc ctcctttaat gatttcaatc
    11041 ttaatgtact tcataatgat tactgctgag gtagcggtaa aaatctgtca acttcatagt
    11101 caaaacacgg ttgaccacat tgacttgatt gattagctgt tggtaatcca gattaactgg
    11161 accgataatg gctagaattc caactccccg ataaggaatg aggaacttac tactaatcac
    11221 cgctaggtca gctaaacagg actcttgacc gtctgcaaca cgaacatttt gcatctgttc
    11281 ctcacgcaac ccctcacgaa tctccaaggc caccttttgc ggttggtcaa agaactgata
    11341 ggctgctaga ttggcaaaat tcaagagatg gaccttgccc gccatcacaa tgttttcgtt
    11401 gaacatttcc ttaaagatgt gttcaaagag atcgatgaca ttatccgttg ttgtaaagta
    11461 acgctggata atctgcggaa tctccgtccg aatcttgtag tgaatatcta aaacggtgtg
    11521 accgaggaaa cgttcctgaa tgatgctctt cagtttcagc aaatcctcct gcaagaagtt
    11581 ccttggaatc agaaactgac tagtaaccgt tcgcgactcg tctagggtaa ataccgccaa
    11641 ggctgtatgt tgccccaaaa caacgatatc aaaggctgtc aaacgttgcc tgctcggctc
    11701 aacatccagt gccactaccg tacagccact caggtctgtt agtaagttag cagcctcttg
    11761 cagaatatcc tccaatttga agaattcctg atcaaaggct ttgacaatct catatacctc
    11821 attttcagcc agccggtcaa aatccagtga gtgtttcaca tagtactgaa aaccagcaac
    11881 acttggcatc cgaccgcttg aagtatgagc cttctcaagc aacccttgtt tttctagttc
    11941 cgccatgtca ttacgaatgg ttgcactgct agagttaata gactcttgca aggcttttga
    12001 tccgacaggt tcgtgcgttt tggtaaagat gtcaataatc agatttaaaa tatcctgctg
    12061 acgctctgta accatctcat cactcctctc tgtctgatca attagcactc aatgcatcca
    12121 agtgctaact tatgattcta ttatacaccc ttagaagaga atgtcaagac aaaaactcaa
    12181 aaaaattagc actcttttat caagagtgct aaaaatcaat ctgaagacct agaaccttgc
    12241 tattcatcta ctcggtattt cctttttagt ctgaaataac catgaattag ataagaaatc
    12301 agaaaagcat ataaaacaaa aataagaaag aaagacatag aaagatcctc tctaaacaaa
    12361 ctcgtacaaa caacaagacc acctaagaaa gtagctgtac aggaacgaag tctagatcgc
    12421 ataacttccc atttgagccc cttactcata tagacttgat cctctggaag taaatcagaa
    12481 gacgatttac gaagaatcga acaagaacct gctcctatca attcccaacc tctatctcta
    12541 aaatcttgca gttcatgctt atatttttta agaaatctag aatcatagat acggtagatg
    12601 acatcgtctg gttgacattg gtcaaaatag aacaaaccaa aacgactcgt tctatacctc
    12661 caacctttca aatgcatctc atgtaaatat tcttcttcct tgtccaaatc aacaatggtg
    12721 aaaatccgaa attctactct gctattcatt gtcttacccc aaaattagaa aacatgcctg
    12781 gcgttattta ttagataatt ctttccactt ttgactcaat ctccaaaaaa tataagaaat
    12841 ctgaatcgca aaaactatca ataaaaccca atctattatg aaaatcaaaa acactttcca
    12901 actgaaagaa ctacctccag tgacaaactt tgagaaaaac ggcagtagag ctaaaaagag
    12961 aagtaaaata ggaagcatcc gcattgttaa aatccgtttg gcataaaaaa atctttattt
    13021 aaacgaaaat attatagcaa aatttacgcc agtttttgaa cggctgatgt agatatttta
    13081 tactttcaaa atgtttaaat gtgattattt atttttgaaa aatagctcac cagcccgact
    13141 gaaagtgctt atagaatgat aataagtcgc ctgccgaaaa cagcggaaaa tagcggtgtt
    13201 atgcggagat aatctgacgc gatgcgaaag tatattgcat acttattttc aacaatttag
    13261 cagagtattt ttataagtgt gatataatag aagtataatt tgttctgata gtttatttta
    13321 tggagaagta gatttttaga atgcggaggg ttcaatatgg ttgagtttat aaagtctaag
    13381 aaagaaatga gtgaggagga tattaaagca aatttcatca ctcctgctat tgtatccaaa
    13441 ggatggaaaa atggtgagca tatcgcttac gaagaatact tcactgatgg tcgaattgag
    13501 gttagaggag ataaggctcg tcgtaaagaa ggaaaaaaat cagactattc actgtattac
    13561 caatttggaa ctcgaattgc aattgttgag gcaaaggata ataaacacag cgttcgagca
    13621 ggattacaac aagctattga atatggagag attttagatg ttccatttgt ttattcttca
    13681 aatggtgatg gctttattga acacgaccgt atcacgagag aagaacgtga gctggagtta
    13741 gacgaattcc ctactcgtga agaattattt tctcgtatga cgaaggaaaa aggattgacg
    13801 tacgaaatta cagaagctat ctcaactcca tactatacag acgccttctc aatgaaaacg
    13861 ccacgctatt atcagcaaat agctatcaac cgtactattg aaacagttgc cagaggacaa
    13921 aaacgagtaa tgtttgtgat ggcaacagga acggggaaaa cgttcatggc ttttcaaatt
    13981 attcatcgcc ttcgaaaagc tggtttggct aaacgagttt tattcttagc ggatagaaac
    14041 atcttagtag accaaacgat ggctgaagac tttaagccat tcgaaaaggt aatgacgaaa
    14101 attacaccaa aacttttgac tgctcctgaa aaattaaatt cttttgaaat ttatctaggg
    14161 ctttatcagc aactaactgg tgaagatgga actgaaacac attatcaaaa atttgacaaa
    14221 gacttctttg atttaatcgt aattgatgaa gcgcaccgtg gttcagctaa ggaaaacagt
    14281 aactggcgta agataattga ttatttcagt tctgcgacac agattgggat gaccgctact
    14341 cctaaagaaa ccaagaatgc ttccaatacg gaatactttg gtgagccaat ctatacttat
    14401 agtttaaaac agggaatcga ggatggtttt ttggctccat atcgtgttat gagggttaat
    14461 ttagatgtgg atgtggatgg ttatcgtcca gaaactggaa aagttgatac taacggacaa
    14521 ttaatagaag ataggtacta cggcaggaaa gattttgata aaaccattgt cattgatgat
    14581 agaacgcaaa gagttgccaa gtttgtttct gattatatga agcaaagcaa tgcacgattt
    14641 gataaaacaa ttgttttttg tgttgatatt gaccatgccg agcgaatgcg tgctgcactt
    14701 gtaaaagaga atctagactt agtccaagaa gactatcgtt atgtcatgca agtaactggt
    14761 gacaacgctg aaggaaaagc tcaactggat aactttatgg atgtcaattc taattttccc
    14821 gctattgtaa caacgtctaa attattaacg acaggagtta atgctaaaac atgtcgtttg
    14881 attgttttag actctaatat ccaatccatg actgaattta aacaaattat tggtcgtggc
    14941 acacgtcttt atcctcaaaa ggggaaagaa ttttttacga ttattgattt tcgaaatgtt
    15001 accaatttgt ttgctgaccc tgattttgat ggtgatcctg tgaaggtgct ggaaacaggt
    15061 gcgaaaacag tcagtggttc tacgcccggt ttcgtagatg aggaaggtga cccagtagaa
    15121 aaatatatcg ttacagacaa gcaggttacc attcttaatt ctactgttca agtattagat
    15181 gaaaacggga aactgattac cgaaagcctg accgactaca ctcggaagaa tatcttaggt
    15241 agctacgcca ctttgaacga ttttatcaca gtttggcata cggcggataa aaagaagctt
    15301 atcttagacg aactttataa aaaaggagtt tatctagatg ctattcgaga gtcggaggga
    15361 atatcagaac aagaaatcga tgattttgat ttactcctaa aacttgccta tggtcaaaaa
    15421 gaattaacca aaacggaacg tatcaataaa ctcaaacaaa gcggatattt atataaatat
    15481 agtgaggaag cgcgtgctgt tttggaaatt ttactgaaca aatacatgga taaaggtatt
    15541 ggagaactcg aaagcattga aacattaaaa cttccagaat ttcagatata tggtggaacc
    15601 ttcaaaatca tcaatactta ttttggagat aaaaaacgat atttacaagc aattaaagaa
    15661 ttggagcaag agctatttac agtagcttaa tgaaaggaaa gtatgtcaat tacatcattt
    15721 gtaaaaagaa ttcaagatat cactcgaaac gatgctggtg ttaatggtga tgctcaacgt
    15781 attgagcaaa tgtcttggtt attattctta aaaatttatg atagccgtga aatggtttgg
    15841 gaattagaag aagacgagta tgagtcaatt atcccagagg aattaaaatg gcgaaattgg
    15901 gctcatgctc aaaatgggga acgggtattg acaggcgatg aattacttga ttttgtcaat
    15961 aacaagttat tcaaagagtt gaaagagctt gaaataactt caaatatgcc tattcgaaaa
    16021 acgattgtta aatcagcttt tgaagatgcg aacaactata tgaaaaatgg cgtcttgtta
    16081 cgccaagtca tcaatgttat tgatgaagtt gatttcaata gccctgaaga tcgtcattcg
    16141 tttaatgata tttacgaaaa aattcttaaa gatattcaaa atgctgggaa ctcaggagaa
    16201 ttttatacgc cacgtgcagc gactgatttt attgccgaag ttcttaaccc aaaacttgga
    16261 gaatcaatgg cagaccttgc ttgcggaaca ggaggcttct tgacttcgac tctgaaccgt
    16321 ttaagtagtc aacgtaaaac tagtgaagat accaaaaaat ataatacagc tgtttttggt
    16381 attgaaaaga aagcatttcc tcatctttta gcagttacaa atctgtttct tcacgaaatt
    16441 gatgacccta aaattgttca tggaaatact ttggagaaaa atgttcgtga atatacggat
    16501 gatgaaaaat ttgacattat tatgatgaat ccaccttttg gagggtcaga attagaaaca
    16561 ataaaaaata actttccagc agaattacgg agttctgaaa cagctgattt atttatggct
    16621 gtcattatgt atcgtttgaa agaaaatggt cgtgttggag ttattttacc tgatggtttt
    16681 ctatttggtg aaggtgtaaa aactcgcttg aaacaaaaac tggtagatga gttcaacttg
    16741 catacgatta ttaggttgcc tcatagtgtc tttgcaccgt atacaggaat ccatacgaac
    16801 attcttttct ttgataaaac aaagaaaaca gaagaaactt ggttttatcg tttagatatg
    16861 ccagatggtt ataaaaattt ctcgaaaact aagccgatga agtcagaaca cttcaatcct
    16921 gttcgtgact ggtgggaaaa tcgtgaagag attctggaag gtaagttcta caaatctaaa
    16981 tcatttacac ctagtgaatt ggctgagttg aattataatt tagaccagtg tggctttcca
    17041 aaagaggaag aggaaatctt agatcccttt gagttgattc agaattatca agcggaaaga
    17101 gcaactttaa atcataagat tgataatgta ttagctgata ttttgcagtt gttggaggac
    17161 aaataatgac accagaacaa cttaaagcaa gtattctcca aagagcgatg gaagggaaat
    17221 tagtgccgca aaatcccaat gacgaacctg caagtgaatt attaaagaga attaaagctg
    17281 aaaaagaaaa acttatcagt gaaggaaaaa tcaaacgaga taaaaaggaa actgagatat
    17341 ttcgtggtga tgatg
//
LOCUS       DAVHSY010000040        16663 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.041, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000040 DAVHSY010000000
VERSION     DAVHSY010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16663
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.041"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            473..1594
                     /gene="mnmA"
                     /locus_tag="VVR43_001638"
     CDS             473..1594
                     /gene="mnmA"
                     /locus_tag="VVR43_001638"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU6149975.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGEKTEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1735..2190
                     /locus_tag="VVR43_001639"
     CDS             1735..2190
                     /locus_tag="VVR43_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6149976.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2200..4113
                     /gene="mnmG"
                     /locus_tag="VVR43_001640"
     CDS             2200..4113
                     /gene="mnmG"
                     /locus_tag="VVR43_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU6149977.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4320..4412)
                     /locus_tag="VVR43_001641"
                     /pseudo
     CDS             complement(4320..4412)
                     /locus_tag="VVR43_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4466..6145)
                     /locus_tag="VVR43_001642"
     CDS             complement(4466..6145)
                     /locus_tag="VVR43_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU6149978.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6147..6380)
                     /locus_tag="VVR43_001643"
     CDS             complement(6147..6380)
                     /locus_tag="VVR43_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU6149979.1"
                     /translation="MIYKVFYQETKERSPRRETTRTLYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6660..6875
                     /locus_tag="VVR43_001644"
     CDS             6660..6875
                     /locus_tag="VVR43_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6149980.1"
                     /translation="MYNLFAFAIGARLVAFIVFVACVYAGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            complement(7198..7350)
                     /gene="cibB"
                     /locus_tag="VVR43_001645"
     CDS             complement(7198..7350)
                     /gene="cibB"
                     /locus_tag="VVR43_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU6149981.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7352..7537)
                     /gene="cibA"
                     /locus_tag="VVR43_001646"
     CDS             complement(7352..7537)
                     /gene="cibA"
                     /locus_tag="VVR43_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU6149982.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7715..8398
                     /gene="tsaB"
                     /locus_tag="VVR43_001647"
     CDS             7715..8398
                     /gene="tsaB"
                     /locus_tag="VVR43_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU6149983.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8395..8832
                     /gene="rimI"
                     /locus_tag="VVR43_001648"
     CDS             8395..8832
                     /gene="rimI"
                     /locus_tag="VVR43_001648"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU6149984.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8822..9832
                     /gene="tsaD"
                     /locus_tag="VVR43_001649"
     CDS             8822..9832
                     /gene="tsaD"
                     /locus_tag="VVR43_001649"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU6149985.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKTFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(9872..11178)
                     /locus_tag="VVR43_001650"
                     /pseudo
     CDS             complement(9872..11178)
                     /locus_tag="VVR43_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11454..11805)
                     /locus_tag="VVR43_001651"
                     /pseudo
     CDS             complement(11454..11805)
                     /locus_tag="VVR43_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(11912..12205)
                     /locus_tag="VVR43_001652"
                     /pseudo
     CDS             complement(11912..12205)
                     /locus_tag="VVR43_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12448..13622
                     /locus_tag="VVR43_001653"
                     /pseudo
     CDS             12448..13622
                     /locus_tag="VVR43_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            13615..14490
                     /locus_tag="VVR43_001654"
     CDS             13615..14490
                     /locus_tag="VVR43_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6149986.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLF"
     gene            14577..16193
                     /locus_tag="VVR43_001655"
     CDS             14577..16193
                     /locus_tag="VVR43_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6149987.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT         5042 a         2945 c         3697 g         4979 t
ORIGIN      
        1 ggcttaggtg cccttgcagt caacacaact gtagatggct ataaagtcaa tgccaatggt
       61 gaatgggttt aagccgatta aattaaatca tgttaagaac atttgacatt ttaattttga
      121 aacaaagata aggttcgatt gaatagattt atgttcgtat tctttaggta cctatcttat
      181 gatttcagga aatgtcatta aaaaaacgac tccttttctc taacttgaaa aatagattag
      241 agaaaatggg ttgttttatt tattatagtt atttgaatga agataagaag aaggtatact
      301 cacatcattc acataatctg tatattgact ataagtttta aaaaacaatt tttaagctct
      361 tccttgtctt ctctaaccaa gcgtgttata atgaatactg ctcaagcgac cttcaatcgt
      421 gaagcacaca cgaccttcaa tcgtgaataa acgaatagat gggagactta ccatgagtga
      481 taactctaaa acacgtgttg tcgtggggat gagtggtggt gttgattcgt cggtgacggc
      541 tcttttgctc aaggagcagg gctacgatgt gatcggtatc ttcatgaaga actgggatga
      601 cacagatgaa aacggcgtct gtacggcgac cgaagattac aaggatgtgg ttgcggtggc
      661 agaccagatt ggcattccct actactctgt caattttgaa aaagagtact gggaccgcgt
      721 ttttgagtat ttcctagcgg aataccgtgc agggcgcacg ccaaatccgg acgttatgtg
      781 caacaaggaa atcaagttca aggccttttt ggactatgcc ataaccttgg gggcagacta
      841 tgtagcgact gggcattatg ctcgagtggc gcgtgatgag gatggtaccg ttcacatgct
      901 tcgtggcgtg gacaatggca aggatcagac ctatttcctc agccaacttt cgcaagaaca
      961 acttcaaaaa accatgttcc cactaggaca tttggaaaag cctgaagtac gcagactagc
     1021 agaagaagca ggcctttcga ctgctaagaa gaaagactcg acagggattt gctttatcgg
     1081 agaaaagaac tttaaaaact ttctcagcaa ctacctgcca gctcagcctg gtcgcatgat
     1141 gactgtggat ggtcgcgata tgggcgagca tgcaggtctt atgtactata caatcggtca
     1201 gcgtggcgga ctcggtatcg gtgggcaaca cggcggtgac aatgcccctt ggttcgttgt
     1261 cggaaaagat ctaagcaaga atattctcta tgtaggacaa ggattctacc atgattcgct
     1321 catgtcaact agcctagaag ccagtcaagt ccactttact cgtgaaatgc cagaagagtt
     1381 tacgctagaa tgtacggcta aattccgtta ccgtcagcct gactctaagg tgaccgttca
     1441 tgtcaaagga gaaaagacag aggtcatctt tgcggaacca caacgcgcga ttacaccagg
     1501 acaggcagtt gtcttttacg atggcgaaga gtgtctaggt ggcggtttga ttgacaatgc
     1561 ttaccgcgat ggacaagttt gtcagtacat ttagattgac aaattttctc aatttgctac
     1621 aataataaca gcaatagaaa tgatggtcaa agctcatgga tgttgcaggc ttttttgtcc
     1681 tgcacttctt tgtagttttg actgtttttg tgtcgtttaa gggaaaggac aagaatgact
     1741 caacaagact ttcggacaaa agtagacaat acggtttttg gtgttcgggc tacagccttg
     1801 attgtccaaa atcacaagct tctagttacc aaagacaagg gcaagtatta cactattgga
     1861 ggtgcgattc aagtcaatga aagcacggaa gacgcggtag tccgtgaagt gaaggaagaa
     1921 ctgggtgtca aagctcaagc tgggcagcta gcttttgtgg ttgaaaatcg ttttgaagtg
     1981 gacggcgttt cctatcacaa tatcgagttt cattatctgg tggatttgct tgaagatgcc
     2041 ccgttgacca tgcaggaaga tgagaaaagg cagccctgtg agtggattga cttggataag
     2101 ctccagaata tccagctagt tccagccttt ttaaaaacag ccctaccaga ttgggaaggc
     2161 caactaagac acattcatct tgaggaatag gagagaaaca tgacttatca ttttactgaa
     2221 gaatacgata ttattgtaat tggtgcggga cacgctgggg ttgaggcttc cttggccgct
     2281 agccgtatgg gctgtaaggt cctgcttgcg accatcaata ttgaaatgct ggctttcatg
     2341 ccttgtaatc cctctatcgg tggttctgcc aaggggattg tcgtgcgtga agtcgatgcc
     2401 ctcggtggcg agatggccaa aaccattgac aagacttaca tccagatgaa gatgctaaac
     2461 acagggaagg ggccagctgt ccgtgccctt cgtgcgcagg ctgacaagga actttactct
     2521 aaggagatgc gcaagacggt tgaaaaccaa gaaaatctga cccttcgtca aaccatgatt
     2581 gatgagattt tggtggaaga tggcaaggtt gtcggtgtgc gtacagccac ccatcaagaa
     2641 tatgctgcta aggctgttat tgtgacgaca gggactgctc tccgtgggga aattatcatc
     2701 ggagacctca agtactcatc aggtcctaac cacagcttgg cttctattaa cctagctgac
     2761 aatctcaagg aactgggtct cgaaatcggt cgtttcaaga caggaacccc tccacgtgtc
     2821 aaggcttctt ctatcaatta cgatgtgaca gaaattcagc caggagacga agtgcctaat
     2881 catttctcat acacttcacg tgatgaggat tatgtcaagg accaagtacc atgctggttg
     2941 acctatacca atggtaccag tcatgagatt atccaaaaca acctccaccg tgcgcctatg
     3001 tttacaggtg tggtcaaggg agtggggcct cgttactgtc cgtcgattga agacaagatt
     3061 gtgcgctttg cggacaagga acgtcaccaa ctcttccttg agccagaagg gcgcaatact
     3121 gaggaagtct atgtgcaagg actttcaacc agtctgcctg aggatgtcca gcgtgacttg
     3181 gtgcattcca tcaaaggttt ggaaaatgca gagatgatgc ggacaggtta tgctattgag
     3241 tatgatatgg tcttgcctca tcagttgcgt gcgactttgg aaaccaagaa aatctcaggt
     3301 ctcttcactg ctggtcagac aaatggaaca tcaggttacg aagaggcagc aggccaaggg
     3361 attatcgcgg gtatcaatgc ggctctgaaa atccaaggca agcctgaatt gattttgaag
     3421 cgcagtgatg gttatatcgg ggtgatgatc gacgacttgg tgaccaaggg aaccattgaa
     3481 ccctaccgtc tcttgaccag tcgtgctgaa taccgtctca ttcttcgtca tgacaatgct
     3541 gatatgcgct tgactgagat gggacgcgag attggccttg tggacgatga acgctgggct
     3601 cgttttgaaa tcaagaaaaa tcaatttgat aatgagatga agcgcctaga cagtatcaaa
     3661 ctcaagccag tcaaggaaac caatgccaag gttgaggaga tgggcttcaa acccttgacc
     3721 gatgcagtga cagccaagga attccttcgc cgtccagaag tttcttacca agatgtggtg
     3781 gccttcatcg gaccagctgc agaagacttg gatgacaaga ttatcgaatt gattgaaaca
     3841 gaaatcaagt atgaaggcta tatttccaaa gccatggacc aggttgccaa gatgaaacgc
     3901 atggaagaaa aacgcattcc ggccaatatc gactgggatg acattgattc tatcgcaacc
     3961 gaagcccgtc agaagttcaa actcatcaat ccagaaacca tcggccaagc cagccgtatt
     4021 tcgggagtaa acccagcaga tatttctatt ttgatggtgt atctggaagg taaaaatcgt
     4081 agtatttcta aaactcttca aaaatcaaaa tgatacgtcg tcggcttctt acgaatgagt
     4141 tcaaagcttg gctttgattc atctccagcc tcccatagtt tcccgaacta tgggagctaa
     4201 ctcaagttat gctttcgctt agccttctag tctgatttcg atttttattg atactcttcg
     4261 aaaatctctt caaaccgcgt caacgtcgcc ttgccgtagg tatggctact gacttcgtca
     4321 gttctatcta caacctcaaa gcagtgcttt gagcaaccta cggctagctt cctagtttgc
     4381 tctttgattt tcattgagta tgagttttaa tctcaaaaga aagcatagag aaaaacagct
     4441 ccgaggacgg ggctgttttc ttgctttatt cttcatctgg tgtgaggatc atcgggatga
     4501 tgatcggttc acgttcggta ttttcataga ggaaggggcg aatagcgttg acaatggcac
     4561 cattgacaga ttgcacgcta gcatccttat ttttcagtgc gatacgaatg gcattgaaga
     4621 ggatacgctg gctttggcga atcaagtctc cagactctct catgtagaca aagcctcggc
     4681 tgaggatatc tgggccagac agaatcatct gcgatttgaa gtcaacagtt gcgactgcta
     4741 gaacgacacc gtcttcagat agatcgcgac gatctttgag gacagctgcg ccaatttcac
     4801 cgatacgatt tccatcgaca tagatatctt gggcgttgaa atgacctgcg atacgagctg
     4861 agtcagcagt aagggcaagc acatcgccat tgctcatgat aaagatattg tccttctcaa
     4921 caccagtatc cactgctagt ccagcgtgga ctttttgcat gcggtattca ccgtggacag
     4981 gcatgaagta ttttggctta atcaagcgga gcatgagttt ttgctcttgc tggccaccgt
     5041 gtccagatgt atggatattg ttcactttac cgtggataac ttcgacacca gcttcagaaa
     5101 tgatgttaat cagcttgttg acgctagtag tgtttccagg gatgggacta gaagagaaga
     5161 taacggtatc acctggttgt aattgtactt gacggtgggt tccgttggcg atacgagaga
     5221 gggctgccat aggctcaccc tgactacctg tacagaggat aagaacttct cctgcaggat
     5281 aatctttgat ttcatttggc tcgataaagg ttcccttagg agctttgatg tagccaagat
     5341 cgattccgtt gacaatggcc ttttccatag aacgaccaaa gaccgcaatc ttgcgtccag
     5401 tcttaacagc agcttctgtt gcctgctgga gacggaagat atttgaggca aaggatgcaa
     5461 agatgatacg tccttcaata ccttggataa tcttcataat ggactgacca acgacttttt
     5521 cagagttggt aaaggttggt acttccgcat ttgtcgagtc agacaggaga cagagcacgc
     5581 cttcttcacc aagcgcagcc atacgatgca agtccgcagg ttctccaact ggagtaaagt
     5641 cgaacttaaa gtcacccgta cagacgattt tcccttgagg agtatgaatg acaatcccca
     5701 aaggctctgg aatagagtga gtcgttctaa agaaagttgc cttgagattt ttaaaggtca
     5761 actcggtgtt gtggttgatt tcgtaaagtt tggcgttgcg caagaggccg tgttcttcga
     5821 gtttcccacg gatcaaagcc aaggcaagcg gtccagcgta gatagggaca tttgcttgct
     5881 tgagtaggaa cggaatccca ccaatgtggt cctcgtgtcc gtgtgtgatt aaaacagcct
     5941 tgacgcggtc gatattgtcc acgatgtaag agtagtcagg aatgacatag tcgataccaa
     6001 gcaagtcatc ttctgggaat ttaatcccag catcgacgat gataatctcg tcttggtatt
     6061 caattccgta agtgtttttc ccgatttctc ctagaccacc gatggcaaaa acgccgactt
     6121 cttcaggttt aagagtgtag gccatattag aactccgtaa tttcgaaggc gccagtttct
     6181 ttttcgtaat cgagcaattt gtcagacaag agttcgatat actcgatatt gtactctggg
     6241 cgattttctt cgacaagttg gcgagcagtg atacggccct caagttctga gctggcatcg
     6301 atgtctaggt aaagcgtgcg tgttgtttca cggcgtgggc tacgttcttt tgtttcttga
     6361 taaaaaactt tgtaaatcat atagttcctt tctatttaca ggtcagctta ttccaaactt
     6421 ttagcagata tttgcttgat ttcattccat tttgtgtcta gattgacctt gattcgttac
     6481 aattatttca attataccac aaaatgaaaa attagtaaaa gacggaaacg agaaagttag
     6541 gggacgattt ctttggtaag cgtttgcaag aataaagaaa atgtattatg ttgataacgg
     6601 aagtgaaatt tattgcttgt cataattcca tatagatttt aagtcaagga ggttgcccta
     6661 tgtataactt atttgctttt gctatcggag ctcgcttggt agcttttatt gtttttgttg
     6721 cttgcgttta tgcggggaat cttctatttg ccaaactgga acgacgacaa accaagttct
     6781 tgtggaaaat gacctttgtg actctctact cgctttttct cctcctcgtg acctatgtcg
     6841 tttggtttgt attttacttt gaattaaatg cttagatgcc ctgcttatgc tggggttttt
     6901 tgtttgggga tgtagagata gtagatttac gacacgaaaa ttccacccca tctatcaaga
     6961 tgaggtggtc tttgcatttt tctaacatga catgacaatg gaattttcaa agcttattat
     7021 ttttatggga gtcattgttc tgatcaaaaa tagagttgaa gcataaaaat aaaacaatac
     7081 aaacagataa atcgaatggt aaagggatgg tagtaatgtt caaatcattg agaatgctga
     7141 gcaaactgta agagatgaag acaataaaat ttatccttct aaaaatgtgt ttcttatcta
     7201 gcatgactta ccaaactttt tacgaaggtc ttttccaatg gtataacctg ccataaataa
     7261 agcgatacca acaccgacac caaagccacc cttgatttct tgcaattcct tattagaaat
     7321 ttcacgataa ttgttcaaat ctttcatcat attaatctcc tcctaaaaaa taaccagctg
     7381 ccaaaccaga acctataagt gctgttccac ctgcaatagc cttccaagat actgctactc
     7441 caaagataac caagggagcg agaccgccat caatatctga taattcattt tcagataagg
     7501 ataaaaattg attgtcaaga atgtcaaaat ttgtcattga actttcctcc ttttttcttg
     7561 ttcactttta tattcggaaa agaaaaggaa aagtgagcat ttttttaaat tatttttagt
     7621 taagtgaggg cactcttgtc tgggggcaaa gaaaattccc atgtgccagc ttttgtagta
     7681 taatagtaag cagacaaaaa gataggaatg tgttatgaaa gtattagctt ttgatacgtc
     7741 cagcaaggct ctttctctgg ctattttaga ggataagcag gttcttgccg agacgacgat
     7801 taatattaag aaaaatcaca gtattactct tatgcctgcc atcgattttt tgatggcaag
     7861 tttggattgg acacccaagg atttggaccg aatcgtggta gctgaagggc cgggtagcta
     7921 tacaggcttg cgaattgcgg tagcaactgc taagacctta gcttacaccc tgaacattga
     7981 gttagttggg atgtcgagtc tcttggctct ggtgccccac caacaagaag gtttgtttgt
     8041 ccccttgatg gatgcgcgtc gcaataatgt ttatgcagga ttttatgaaa atgccaaacc
     8101 tgtcatggca gaagcgcacc tatcttttga agaggtgcta gaaaaagtca agggtactag
     8161 tcaggtaacc tttgtcggag aagttggccc ctttgttgag cagattcaaa aacacttgcc
     8221 aaggactgat tacaaagaaa cattgcccaa tgcagctaat ctagctcttt tggcctggga
     8281 caaggaagca gactccttgc atgattttgt gccgaattac ctcaaacgag tcgaggctga
     8341 ggaaaactgg ctcaagaacc ataccgagtc tggcgagtct tacattaaac gcctatgata
     8401 gaaatcaagc gaattcaaca acagcctgac ctagctcaag ccatctacgc tgttatggca
     8461 gctgtttacc tagtcagtcc ttggactctg gagcaaatcc aagcagatct gtcccaagac
     8521 cagacttggt atgcattggc ttatgatggg gcagaagtga ttggatttct agctgtgcag
     8581 gagaatcttt ttgaagcaga agtcctgcaa atcgctgtca aaggagctta tcagggtcag
     8641 ggaattgcgt cagccttgtt tgctcaattg ccgacagaca aggaaatttt cctcgaagtc
     8701 agacagtcaa atcaacgagc gcaagcattt tacaagaaag aaaagatggc agttatcgct
     8761 gagcgaaagg cctactacca tgacccagtc gaggacgcca ttatcatgaa gagagaaata
     8821 gatgaaggat agatatattt tagcatttga gacatcctgt gatgagacca gtgtcgccgt
     8881 cttgaaaaac gacgatgagc tcttgtccaa tgtcattgct agtcaaattg agagtcacaa
     8941 acgttttggt ggcgtagtgc ccgaagtagc cagtcgtcac catgtcgagg tcattacagc
     9001 ctgtatcgag gaggcattgg cagaagcagg gattaccgaa gaggacgtga cagctgttgc
     9061 ggttacctat ggaccgggct tagtcggagc cttgctagtt ggcttgtcag ctgccaagac
     9121 ctttgcttgg gctcacggac ttccgctgat ccctgttaat cacatggctg ggcacctcat
     9181 ggccgctcag agtgtggagc ctttggagtt tcctttgttg gcactcttgg tcagcggtgg
     9241 ccacacagag ttggtctatg tttcggaggc aggagattat aagattgttg gggagacacg
     9301 agacgatgca gttggggagg cttatgacaa ggtcggccgt gtcatgggct tgacctatcc
     9361 tgcaggtcgt gagattgacg agctggctca tcaggggcag gatatttatg atttcccccg
     9421 tgccatgatt aaggaagata atctggagtt ctccttctca ggtttgaaat ctgcctttat
     9481 caatctttat cacaatgccg agcaaaaggg agaaagcctg tctacagaag atttgtgtgc
     9541 ttccttccaa gcagcagtta tggacattct catggcaaaa accaagaagg ctttggagaa
     9601 atatcctgtt aaaaccctgg ttgtggcagg tggtgtggca gccaataaag gtctcagaga
     9661 acgcctagca gccgaaatca cagatgtcaa ggttatcatc ccccctctgc gactctgcgg
     9721 agacaatgca ggtatgattg cctatgccag cgtcagcgag tggaacaaag aaaacttcgc
     9781 aggctgggac ctcaatgcca aaccaagtct tgcctttgat accatggaat aaagagtggc
     9841 tctttgtcaa gtgtagtggg taggcgaaaa gctacaatct ggagagtacg aaattcgtac
     9901 tctctttttt gatgttcaaa gtcatcaaaa tccgtttttt aaaattgtta aagttccgga
     9961 aaccaaaggc tttgcgcttg ataatcttaa tcaaattatt ggtcgcttca agtttagcgt
    10021 tggaataagg cagcttaagt gcgttgataa tcttatctct atcccttaaa aaagtccaaa
    10081 agaccgtttg aaaaagcgga tgaaccgttg gcagttcttg ctcaatcaat ccaaagaaat
    10141 ggtcggcatt cttctcttga aaatgaaaga gcaggagttg atagagttcg tagtgaacct
    10201 gtaatccctc agagtaagaa agcagcttat ctcgtacttc ccgatgggtt aagtgcattc
    10261 gaaacgtggg ctgatagaat cgtttctgac agagcttgaa gctatactgg tgtagtaaat
    10321 cagtccagtg gactgattta gcccgagcct agaaacgaaa aagcgagggt tccaaaagcg
    10381 cttgagcgcc cgatactcca aggattttcg gtcaaattgg ttcatgattt ggattcgtac
    10441 tcggttcata gctcggctca gatgttggac aatgtggaag cggtcaagaa caatcttcgc
    10501 ctttggaaag agttgcttag cgagccgata ataagggctg tacatgtcca tggtgatgac
    10561 ctcgaccagc tcccgaacct ctctctgata gcgttggaaa tggtttcgaa tcaccgcatg
    10621 agttcgcccg tctaaaattg cgaggatgga tttggactca aaatcttggg caatgaagct
    10681 cattttgctc tttttgaagc tatactcatc ccaactcata acttttggca acttggtcca
    10741 atcggtttca aacttaaatt ccctcagttt tcggatgacg gtggaagttg agaccgccaa
    10801 tctgtgggca atctcagtca tagactgctt ttcaaggagg agctgagcga ttttttgtct
    10861 caccatgttg gaaatctggc aatttttctt gacaatggat gtttgagaaa cgaccacctt
    10921 aaggcaattc ttgcactgaa agcggcgctt tttgagatgc agtaccgtgg gtaaaccctg
    10981 acagtcgaga agcggaattt tagaggcttt ctggaagtcg tatttgatca tcttcccttg
    11041 acaatgagga caaggaggag cgggggaatc caactttgcc tgaacgacta gatgggtttg
    11101 gtatttcaga acagacaaga ttttgatatt tttgtcttcc aatccgagca aatctgtggt
    11161 attcttaagt tgttccatat gaaccctttc taatgagttg gttagacgct tttcattata
    11221 ggtcatatgg ggcttttttt ctacaagaaa cgaccctata attcctgggg tgggattacc
    11281 cactacagaa attatagagc caaagcattc caaagtcttg tctgactctg gaatgttttc
    11341 tgttcacagt tgttttgtaa ctgcctaata agtaaccgcg ctataacgag gtatctaccg
    11401 agattgtcaa ttctccagta tactgttata aaaaacaaaa ctggaggatt tttttatgtc
    11461 cccccatcgt cccatcgact gttccgtagc tgcccaataa cggagtatag tcggctgaaa
    11521 caagaatagg acaaaagtgc ctcaagaaaa gcatcgtaat ttgacaatat tattctgaga
    11581 tgtttttgat gtaagcccat attttctcaa tgggattata ctcgggtgaa taggtaggaa
    11641 gtggtaacag tctatgccct gctccttaca catgttcatt ctgtgaaacc ttgcatggtc
    11701 cataatgata agggatggtg tatctaaagt aggtagtaag aatttttgga agcaagcttc
    11761 gaaaaagtca ctcgtcatcg tatctttata ggtcatcgga gccatagtat attgaaacaa
    11821 aaaagggcat tagtacttct ataacagtat cgcaatctct ggtgtgcgtt gtctcgatct
    11881 taattcaaat aattatatct tcttccagag agactaactg cctgctcaag gctcgatcat
    11941 attcgagata aaaataggtc tcaacccctg tctcataaat ataaatagga gtcaggtagc
    12001 ttaagtgatt caattcttta aggaaccgat ttactttttc tgggtcttgt tcgcagtagg
    12061 tacggctctt ttttagacta tatcccatag cctttagagc gtaatgaata gttgttggag
    12121 gacagttgaa ttcagcagct atttcagtca aataagcatc gggatgagtt tcaatataga
    12181 tctttaattt atctctatca actttttcaa ttaatagtgg aagttttctt aaagttagtg
    12241 tgttgaaacg tttttataca gtgctaaaat ttgaagtgta gtgcagatgt atttgtaata
    12301 gtattatagc aattctttgg agaaggtcga gacaagagaa aataggtatc tttgagatat
    12361 aagcatgatt tactataaaa ttattgagtt attcataaaa atttctctat caaatatcat
    12421 aatgcgtcgt ttaaggagat ggttacaatg caatatagtt gtggaaaaat aaatattaat
    12481 atccctgatg gatatggaga cattaaggat atagtgtttt cggctcatat tatagttagg
    12541 tataataatg gacattgtgg aggtatagat ccgcatataa ttggactttg taaaaagcag
    12601 atcagaagga tgtctctata tcctattttg ataatcgtat ctagagattc aaaggttatt
    12661 gatgattata aaaatttaga tattgcctat gttgattgta ctcaatgttc aaataatttt
    12721 gaaactgcct tacacgttaa aaatatttta aaattattaa aaatccgact tatacactgt
    12781 catggctact caactaatta ttttttatat atgttaaaaa aacttgacaa gaatggattt
    12841 ggaaaggtta agacagtgat aacatgccat ggatgggttg aatataactt aaaaaagaaa
    12901 ttcttgactt attttgattt ttggacatat tctatgggag atgcttttat ttgtgtatct
    12961 gaaactatga aaaaaagatt ggagagtata ataaaaaaat aagaagatag ttgcaataaa
    13021 taacggaatt aatgtatcaa atagcgattt agatgtagta ggtgttcaag actttaaaaa
    13081 agaattttgt attccaaata acaaaaaaat catttgttat gttgaaaggt tggatccaga
    13141 aaaaaggccg gatagattcc ttgaatttgc agaaaaatta tttttagtca gagaagatgt
    13201 gatttttatt atggctggaa atggtagtat gtgggctgct ttgaaagaaa aaatttgcca
    13261 tttgaaatgt agagataatt tcaggttact tggtgaaatc tatccagcta ctatagttta
    13321 ccaaatatcg gatttattgt atattccttc tgatacagaa ggaataccta tgtgtgtttt
    13381 agagtcaatg tcacaaggaa ctccggtttt agctagtaat gttggcgggt taagtgaaat
    13441 tattgaacat agggttgatg gatttttatt tgagaaggaa gatgttgagg gagtgtgtgc
    13501 ttgtgctaat tttttactca atgattctga gtatttgaaa tatataggtg agaatagtaa
    13561 atcaaaaata agaaaacatg agagtatatg atgaattatt agagaagagt agtcatggat
    13621 aggaatatag atcaagaatt agtaagtatt ataataccaa cacataatag gtatgaatct
    13681 ctgattagag ctgtgaaaag ttgtttacat caaagttata aaaatatcga agttataatt
    13741 attgatgata attatagtaa tgtaaattta agaaataaaa ttatccatca atttggctat
    13801 accaatcata gaattaagtt aattttaagt aatgaagatt taggtgcaac taatgccaga
    13861 aacataggta tcaaaaattc tagaggtaag tatatatcat ttttagacga tgatgatgaa
    13921 tatatgccag atcgaatttt aaagttgatg gcttgtttta aaaagagtag aatgaagaat
    13981 ttagctttag tttatagtta tggaataata atttatccaa atggtacacg agaagaggag
    14041 aagaccgatt ttgttggaaa tcccttgttt gttcaaatgg ttcacaatat agcaggtacg
    14101 tcattttggt tgtgtaaaaa agaggtgcta gaattaatta atggttttga gaaaatagat
    14161 tcacatcagg acggtgttgt tttattaaaa ctacttgctc aaggatacca aattgatata
    14221 gtgcgagaat tcttggtgaa ttactacgct cacagtaaag aaaacggtat cactggagtg
    14281 acacaaaaaa caattaatgc agatgaagaa tattataatt actgtaggaa atattttaat
    14341 ttattgagtt tcaacgagag aatattggtt acaaagaaat attattcttt aaacataaag
    14401 cggttactat taataggaga caaatgcaag gctttaaaag taatcaagaa ggcaagagaa
    14461 gaaaaaattt ttaacgaatt tcttttttga aatatatgtt attatatcat tttggttttt
    14521 tctattgtat atatgacaac tatgttcaat taaaatttag aaagtgagaa actattgtgt
    14581 atactattat aaaatcaaat ataaaaaaat ttagtttatt aacgatattt attgttgctg
    14641 gtcaattatt gctaatttat gcagcaacta ttaatgctct ggtgttgaat gaattaattg
    14701 cgatgaattt agagcggttt ttgaaattgt caatctacca aatgattgtc tggtgtggga
    14761 taatattcct tgactgggta gtgaaaaatt atcaggttga agtgatccaa gagtttaatc
    14821 tagagattcg aaatagagtt gccacagaca tctctaactc tacctatcaa gaatttcata
    14881 gtaaatcatc aggaacatat ctttcgtggc taaataatga tgttcagact ttaaatgatc
    14941 aggcttttaa acaacttttt ttagtaataa aaggaatttc tggtactata tttgcagttg
    15001 tgactcttaa tcactatcat tggtcattga ctgtagccac cttgttttca ttaatgatta
    15061 tgctacttgt accaaaaatc tttgcatcga aaatgcgaga agttagtcta aatttaacta
    15121 gccaaaatga agctttttta aaatctagtg agactatatt gaatggattt gatgtgttag
    15181 cgtccttgaa tcttttatat gtattgccta agaaaattaa agaagcagga attttattaa
    15241 agatggttat acaaagaaag acaactgtag aaacgttagc aggcgctatt agcttctttc
    15301 tcaatatttt ttttcagata tctctcgttt ttttaacagg ctatcttgca ataaaaggaa
    15361 tagtgaaaat tggtactatt gaagcaatag gagcactaac aggtgttatt tttacagcgc
    15421 taggtgaatt aggaggtcaa ttatcctcta ttattggtac gaagcctatt tttttaaaat
    15481 tgtattcaat taatccaatt gagtcaaata aaatgaatga tatcgaacca aatgaggtga
    15541 atagagattt tccgttatat gaagcaaaaa atatttgcta taagtatgga gataaagaaa
    15601 tattaaaaaa cttaaatttt tgttttcaac gtaatgaaaa gtatttaatt ttaggtgaaa
    15661 gtggaagcgg gaaatctaca ttattaaaat tattgaatgg ctttttgaga gattatagtg
    15721 gagaattgcg attctgtggg gatgatataa aaaaaacctc ctatttaaat atggtttcga
    15781 atgttctata tgtagatcaa aaagcttatt tgtttgaagg tacgattaga gataatattt
    15841 tattggaaga aaattatact gatgaagaaa tactacagtc tttagaacaa gttggtttga
    15901 gtgtaaaaga ttttcctaat aacattttag attattatgt tggtgatgat gggagattac
    15961 tgtcaggagg gcagaaacaa aaaattactt tagctagagg cctaattaga aataagaaaa
    16021 tagtattaat tgacgaggga acttctgcta tcgataggag aacttcgtta gcgattgaac
    16081 gtaagatatt agatagagag gatttgactg tcattattgt tacccatgct ccgcatccgg
    16141 aacttaaaca atattttact aagatatatc aatttccaaa ggattttatt taagaatata
    16201 ggggagggaa acatgagatt ctattgtgaa gcttatgagg taattactga agagaaaaaa
    16261 gtatacttta atgatattga gttagaagtt aagtattcct ctgtcgaaga attgtttata
    16321 atatgtgaga aattattaga taagaaaaaa gtatcatttt ttatgtagat gagaaaccct
    16381 taaggtatct gttatttgac tatatatttc tactagttct agctaaaaaa atatcccaat
    16441 cttatgaact gcaccccaaa agttagattt attctgtcta acttttgggg tgcagttcat
    16501 tttgcatagt tttggcattc atcctagata tccatataaa atgtctgaga ttgttgaaat
    16561 gtctaaaaaa atatcagatc taaacgataa aaaagaattt cacaaaaaga actgtgagtt
    16621 gaggtttcaa gatagtgttc ttgataacat aaatagtgtc ctg
//
LOCUS       DAVHSY010000041        16533 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.042, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000041 DAVHSY010000000
VERSION     DAVHSY010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16533
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.042"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(124..840)
                     /locus_tag="VVR43_001656"
     CDS             complement(124..840)
                     /locus_tag="VVR43_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6149988.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFISRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            1188..2975
                     /locus_tag="VVR43_001657"
     CDS             1188..2975
                     /locus_tag="VVR43_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU6149989.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            2972..3448
                     /locus_tag="VVR43_001658"
     CDS             2972..3448
                     /locus_tag="VVR43_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU6149990.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            3476..4381
                     /locus_tag="VVR43_001659"
     CDS             3476..4381
                     /locus_tag="VVR43_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU6149991.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            4368..5183
                     /locus_tag="VVR43_001660"
     CDS             4368..5183
                     /locus_tag="VVR43_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6149992.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            5190..5594
                     /locus_tag="VVR43_001661"
     CDS             5190..5594
                     /locus_tag="VVR43_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6149993.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            5888..7054
                     /locus_tag="VVR43_001662"
     CDS             5888..7054
                     /locus_tag="VVR43_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU6149994.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            7170..8207
                     /locus_tag="VVR43_001663"
     CDS             7170..8207
                     /locus_tag="VVR43_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU6149995.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYET
                     IYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            8414..9268
                     /locus_tag="VVR43_001664"
     CDS             8414..9268
                     /locus_tag="VVR43_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6149996.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            9418..9675
                     /locus_tag="VVR43_001665"
     CDS             9418..9675
                     /locus_tag="VVR43_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEU6149997.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(9888..9971)
                     /locus_tag="VVR43_001666"
                     /pseudo
     CDS             complement(9888..9971)
                     /locus_tag="VVR43_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
     gene            complement(10005..10097)
                     /locus_tag="VVR43_001667"
                     /pseudo
     CDS             complement(10005..10097)
                     /locus_tag="VVR43_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10133..10429)
                     /locus_tag="VVR43_001668"
     CDS             complement(10133..10429)
                     /locus_tag="VVR43_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU6149998.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
     gene            complement(10419..10580)
                     /locus_tag="VVR43_001669"
     CDS             complement(10419..10580)
                     /locus_tag="VVR43_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEU6149999.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            10650..11414
                     /locus_tag="VVR43_001670"
     CDS             10650..11414
                     /locus_tag="VVR43_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU6150000.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(11654..11806)
                     /locus_tag="VVR43_001671"
     CDS             complement(11654..11806)
                     /locus_tag="VVR43_001671"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150001.1"
                     /translation="MKTKASIRKLVTGCSKHCFEVADRTDEVSSKHCFEVADRTDEVS
                     NIYTAR"
     gene            12024..13403
                     /locus_tag="VVR43_001672"
     CDS             12024..13403
                     /locus_tag="VVR43_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU6150002.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            13417..14082
                     /locus_tag="VVR43_001673"
     CDS             13417..14082
                     /locus_tag="VVR43_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU6150003.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            14217..14375
                     /locus_tag="VVR43_001674"
     CDS             14217..14375
                     /locus_tag="VVR43_001674"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150004.1"
                     /translation="MKIKDQTRKLATGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            14437..14976
                     /locus_tag="VVR43_001675"
     CDS             14437..14976
                     /locus_tag="VVR43_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6150005.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQKNKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTALLRASQF"
     gene            15043..15453
                     /locus_tag="VVR43_001676"
     CDS             15043..15453
                     /locus_tag="VVR43_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU6150006.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQENPKVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            15569..>16533
                     /gene="pavB"
                     /locus_tag="VVR43_001677"
     CDS             15569..>16533
                     /gene="pavB"
                     /locus_tag="VVR43_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEU6150007.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQENPELTDALKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVKDSIDVPAAYLE"
BASE COUNT         4640 a         3100 c         3735 g         5058 t
ORIGIN      
        1 ggttctattt ctataaaata ttccacaaat tatagaatct tccaaaaata ggtaagcgct
       61 acctttttgg tgtggtataa taagcataga aaaagcccga gcgattaggc tcaggctttc
      121 ttcttagtga tcacggtcac atgagatgaa tttaatcttg tagtaatcag atcgtttgta
      181 agtttcactg tattctaaaa cttggccagt tgattcgagt ttggtgattt tagtttgtag
      241 gacagtaggg aattgttcat cgactccgag gactgaagcc gcatgttctg gagttggaaa
      301 gactatttcg ttgatttctt caaagtgttc atcattcatg tgaatgtggt agtctaactt
      361 gaaacgatta tagatagaac tatagtattc aagatttgga taatttgcgt tgatatattg
      421 ttctgggatg taggatgtat ggtagatata aacgacaccg tttgattcgc ggatacgttc
      481 aatcttgtag tagaattgat cgccgcgtag acccaatttt tccaagtaaa caagcttgtt
      541 tccgcgttca attgaaagaa cagttacctt atcatcttta gcattgaaga gttcaatatc
      601 tgaaaactct acaagcttgt gtttgcgtgc acgtgaaatg aaggttcctt ttccttgttg
      661 gcggacaata tagccatctt tggcaaggtc gtttaaggcg cgaacaactg tgatagagct
      721 gacatcgtac attgaaatga gttctgcttc agtgtaaaat ttatctccac tgctaaactg
      781 cccagagatg attttatttt ttaattcgtc ttttatgtat tgatatttgg gaattgccat
      841 atttttacct ctattttcct tctccataga aaattttacc ataaaagcga aaaaaatagt
      901 agtcttttga ataaaaaatt agaataatag tttgaaaaat taagcgatat agggattgct
      961 catattttat aaatgcattc tatacaaaat tattttaggt actatattcc aaatttaaag
     1021 agcgtttgaa atgggtctaa aaatgtttga aactaattga atgtgtgtat aatagtaaaa
     1081 atgcagtaaa tatcccgaca atttctattg acaattcaaa cagattggtt tataattaat
     1141 ataacaacaa atgaaagcgc aaactttcgc ggtcggaagg tagttttatg acacgatttg
     1201 agatacgaga tgatttctat ctcgatggaa aatcatttaa gattttatct ggtgccattc
     1261 attattttag ggttcctcca gaggattggt atcattcgct ctataacttg aaggctcttg
     1321 gttttaatac ggtagagact tatgttgctt ggaatttaca cgagcctcgt gaaggtgagt
     1381 ttcattttga aggtgatctg gatttagaga aatttctcca aatagcgcag gatttgggtc
     1441 tctacgcaat tgtgcgtccg tctccattta tctgtgcgga atgggaattc ggtggcttac
     1501 cagcttggct cttgaccaag aacatgcgaa ttcgctcatc cgacccagca tatatcgagg
     1561 cagttggtcg ctactatgat cagttattgc caagactggt gcctcgtttg ttggacaatg
     1621 gtggcaatat tctcatgatg caggttgaaa atgagtatgg ttcttacgga gaagataagg
     1681 cttacctgag agcgattcga cagctaatgg aagagtgtgg cgtaacctgt cccctcttta
     1741 catcagatgg tccatggcga gctactctga aagctggaac cttaattgaa gaggacctct
     1801 ttgtaacagg aaactttggt tctaaggcac cttacaactt ttcgcagatg caggaattct
     1861 ttgatgaaca tggtaagaaa tggccactca tgtgtatgga gttctgggat ggttggttca
     1921 atcgctggaa agaaccgatt atcacacggg atcctaagga attggcagat gcagttcgag
     1981 aggttttgga acaaggatct atcaatcttt acatgttcca cggtggtaca aactttggtt
     2041 tcatgaatgg ttgctcggct cgaggaactt tggacctgcc acaagttacg tcttatgatt
     2101 acgatgccct tctggatgaa gaaggaaatc caactgctaa atatcttgca gtcaagaaga
     2161 tgatggcaac acatttttca gagtatccgc agttggaacc actctacaaa gagagtatgg
     2221 agttggatgc tattccacta gttgaaaaag tttctttgtt tgaaacctta gatagcttgt
     2281 caagtcctgt agaaagtctc tatcctcaaa agatggagga gctgggacaa agttatggct
     2341 acctacttta tcgaacagaa acaaactggg atgcagaaga agaaagactt cgtatcattg
     2401 atggtcgaga tagggcccag ctgtatgtcg atggtcagtg ggttaaaact caatatcaga
     2461 cagagattgg ggaagatatt ttttatcaag gtaaaaagaa agggctatct aggttagata
     2521 tcttgataga aaatatgggg cgtgtcaact atgggcataa gttcttagcg gatacgcaac
     2581 gtaagggaat tcggacaggg gtctgtaagg atctgcattt cttactaaac tggaaacact
     2641 atccactccc actagacaat cctgagaaaa ttgatttttc aaaaggatgg actcaaggac
     2701 aaccagcctt ttacgcttat gactttacag tcgaagagcc aaaagatact tacctagact
     2761 tgtctgagtt tggtaagggg gttgcctttg tcaatgggca gaatctagga cgtttttgga
     2821 acgttggccc aactctctca ctttatatcc ctcatagcta tctcaaggaa ggtgccaacc
     2881 gcatcattat ctttgaaaca gaaggtcaat ataaagaaga gattcattta actcgtaaac
     2941 ctacactaaa acatataaag ggggaaaact tatgacaatt gtaggatgcc gtattgatgg
     3001 acgtttgatc cacggacaag tagccaatct ttgggctgga aaactaaatg tttcacgcat
     3061 tatggttgta gacgacgaag ttgtcaacaa cgatattgaa aagagtggtt tgaaacttgc
     3121 gacaccacca ggtgtgaaat tgagtatttt gccagttgag aaagctgcag ccaatattct
     3181 tgctggcaaa tacgatagcc aacgtctctt tatcgtggct cgtaaaccag accgcttcct
     3241 tggtttggta gaagcaggtg taccacttga aacccttaat gttgggaata tgtctcaaac
     3301 accagaaact cgttctatta cacgttctat caacgtagta gacaaggatg tggaagactt
     3361 ccacaaactg gcagaaaaag gtgttaaact tactgctcag atggttccaa atgatccaat
     3421 ttcagacttt ttgagcttat taaaatagga aaaaaatttt taggaggtca ttgttatgat
     3481 acaatggtgg caaattttac ttctcacttt gtactcagct tatcaaatct gtgatgagtt
     3541 gacgatcgtt tcatctgcag gttcccctgt atttgctggt ttcattactg gtttaatcat
     3601 gggagatgtg actactggtt tacttatcgg tggtaacttg caactgttcg ttcttggggt
     3661 tggtaccttc ggtggtgctt ctcgtatcga cgcaacttct ggtgcggttc ttgcgacagc
     3721 cttctctgtt tcacaaggaa ttgatgcacc gcttgccatt actacaatcg ctgtaccagt
     3781 agcagctctc ttgacttact tcgacgttct tggtcgtatg actactacct tcttcgctca
     3841 ccgtgtggat gctgcaatcg aacgctttga ctataaaggt attgaacgca actacttgct
     3901 tggtgcgatt ccgtgggctc tatctcgtgc ccttccagtc ttctttgccc ttgcttttgg
     3961 tggtgccttt gtacaatcag tagtagactt cgttgaagcc tacaaatggg ttgcagatgg
     4021 cttgacactt gcaggacgta tgcttccagg tcttggattt gcaatcttgc ttcgttacct
     4081 tccagttaaa cgtaaccttc actaccttgc tatgggattt ggtttgacag ctatgttgac
     4141 tgttctttac tcatatgtaa caggtcttgg tggcgctgtt gctggtatcg taggtactct
     4201 tcctgctgaa gttgctgaaa aaattggttt cgtgaacaac ttcaaaggtt tgtctatgat
     4261 tggtatttct atcgtaggta ttttccttgc agtgcttcac ttcaaaaata gccaaaaagt
     4321 agctgtagca gcaccttcta caccatcaga aagtggggaa atcgaagatg acgaattcta
     4381 attacaaact tacaaaagaa gattttaatc aaatcaacaa acgtagcttg tttactttcc
     4441 aattaggttg gaactacgaa cgtatgcaag cttctggtta cctttacatg atcttgcctc
     4501 agttgcgtaa aatgtatggt gatggaactc ctgaattgaa agaaatgatg aaagttcata
     4561 ctcaattctt caatacttca ccattcttcc ataccattat cgctggtttt gaccttgcca
     4621 tggaagaaaa agatggtgta ggttcaaaag acgccgttaa cggtatcaag acaggtttga
     4681 tgggaccatt cgctcctctt ggggatacaa tctttggttc acttgtacct gctatcatgg
     4741 ggtcagtcgc agcaactatg gctatcgctg gccaaccttg ggggatcttc ctttggattg
     4801 cagttgcagt agcgtatgac atcttccgtt ggaaacagtt ggaatttgct tacaaagaag
     4861 gggttaacct tatcaacaac atgcaaagta ccttgacagc tttgattgac gctgcatctg
     4921 tacttggtgt cttcatgatg ggtgctcttg tagcaacagt gattaacttt gaaatttctt
     4981 acaagttgcc aatcggtgaa aagatgattg atttccaaga catcttgaac caaatcttcc
     5041 cacgtttgct tccagcaatc tttactgcct ttatcttctg gttgcttggt aagaaaggta
     5101 tgaactctac taaagctatc ggtattatta tcgtacttgc tttggctctt tctgcccttg
     5161 gtcactttgc acttggaatg taattcctta tgactaaatc attaattttg gtgagccatg
     5221 gtcgcttctg tgaggagctt agaggtagca cagaaatgat tatgggccca caagacaaca
     5281 tttacacagt agctcttctt ccagaagatg gcccagaaga atttactgct aaatttgaag
     5341 ctgttattga aggattggat gatttcctag tctttgcgga tcttctcggt gggacacctt
     5401 gtaatgtggt gagtcgcttg atcatggaag gtcgtgatat tgacctttac gcagggatga
     5461 atcttccaat ggtgattgaa tttatcaatg cgagccttac aggcgcagat gcggactaca
     5521 agagccgtgc tgcagaaagc attgtgaaag ttaatgacct gttagcgggc ttcgatgatg
     5581 acgaagatga ataatactct tcgaaaatct cttcaaacta cgtcaacgtc gccttgccgt
     5641 aggtatatgt tactgacttc gtcaatctta tccggcaacc tcaaaacggt gttttgagct
     5701 gacttcgtca gttctatctg caacctcaaa gcagtgcttt gagcagcctg cggctagttt
     5761 cctattttag ttggaactcg attcaattca tgtgacaacg tgaaaatcgt tagagcattt
     5821 tatatagaat atacatggga atggagctta ctcccattcc catatttaat agaaaaagag
     5881 gaactcaatg ctacattata caaaagaaga cttgctcgaa ttgggtgcag aaatcactac
     5941 gcgtgaaatc taccaacaac ctgatgtatg gagagaagct tttgaatttt atcaagcaaa
     6001 acgtgaagaa attgcagcct tcctacaaga aatcgctgat aaacatgact atattaaggt
     6061 tatcttgaca ggtgctggga cttctgctta tgtgggagac accttgctac cttactttaa
     6121 ggaagtctat gacgaacgca aatggaattt caatgctatt gcgacaacag atatcgttgc
     6181 caatccagca acctatttga aaaaagatgt ggcaactgtc cttgtgtctt ttgctcgtag
     6241 tgggaactcg cctgaaagtg tggcgactgt tgatttggcc aaatccttgg tggatgagct
     6301 ttatcaagtg acgattactt gtgcagcaga tggtaaattg gctcttcaag ctcacggtga
     6361 tgaccgtaat ctcttgctct tgcaaccagc tgtctctaat gatgctggat ttgccatgac
     6421 ttctagcttt acgtctatga tgttgacagc tctcttggtc tttgatccta cagaatttgc
     6481 tgttaagtct gaacgttttg aagttgtatc tagtcttgcc cgtaaagttt tagacaaggc
     6541 agaagatgtc aaagagcttg ttgatttaga ctttaaccgt gtcatctatc taggcgctgg
     6601 tcctttcttt ggacttgctc atgaagctca gctcaagatt ttggaattaa ctgctggtca
     6661 agttgcgacc atgtatgaaa gcccagttgg cttccgtcac ggtccaaaat ctcttatcaa
     6721 cgacaataca gttgttttgg tctttggtac aacgacagac tacactcgta agtacgactt
     6781 ggacttggtt cgtgaagttg ctggtgacca gattgctcgt cgtgttgtgc ttttgagtga
     6841 tcaagctttt ggtcttgaaa atgtcaaaga agtggccctt ggttgtggcg gtgtcttgaa
     6901 tgatatttac cgtgtcttcc cttacatcgt ttatgcccaa ctctttgccc tattgacttc
     6961 actcaaggta gaaaataaac cagatacacc gtctcctaca ggtacagtaa accgtgtagt
     7021 acaaggtgtc ataattcacg aatatcaaaa gtaagacagt gtttatgaat tcttgacaag
     7081 aggatttgta aattatcaga taaaccatag attgtcagta cgctttctat ggtttgtttg
     7141 cttgagagaa atagtaaaag gagaacagaa tgaaagcata cacagagcgt gtatttggaa
     7201 atgttgaggg cgaggatgtc ttggcctatc gatttgagac agacggtggc taccaacttg
     7261 aggttatgac ttatggtgcg accatcttgc gctatgtcgc acctgacaag gctggaaatt
     7321 ttgccaatgt tatcttggga tttgatgact ttgatagtta tgtaggcaat agtcccaagc
     7381 atggagcaag tgtaggtcct gtagcgggtc gtattgcagg tgcgaccttt gagctcaatg
     7441 gtaagaccta tgaccttgag gttaataatg ctagcaactg taatcacagt ggttcaactg
     7501 gttgggattc cagcttgttt gaagttgaag aagtaagcga tcatggcttg actctctaca
     7561 cagagcgtac agatgggaca ggagggttcc ctggaaatct caagatttgg atcagttatc
     7621 acttggaaga aactggtgcc tatgaaacca tctacaaggt aacgaccgat caggatacgc
     7681 tagtcaatcc aaccaaccac agctatttca acttgtctgg tgatttcacg cagacgattg
     7741 accgtcatgt cttccaacta aacacagagg gcatttactc aatcgctcct gacggtgttc
     7801 ctgccaaaac tccagaagcc aaccgtgatg tggtcaaaca catctacaat ggtaccttgt
     7861 tgaaggatat ctttgcagaa gaagatgagc aaatccagct ggcatcaggt ttggatcacc
     7921 catttgccct tcctgcaggc catgacaatg ctggattcct ttatgaccaa aattcaggtc
     7981 gcttcctgct tttcaagaca gaagctcctt gctttgtggt ctacacagca aactttgtgg
     8041 atgaaagtgt catcatagga ggtcagccaa tgctacagca caatgggatt gctcttgaag
     8101 cgcaagcttt accagatgcc attcacagtg accttaaagg ccaagtcatt cttaaagctg
     8161 gtcaaacctt caccagtaag acacgttatg aacttgttgt gaaataaaaa agctggtcaa
     8221 aaagtcttta aaattaaaat aacgcatatt gtcaggtgat gaaaagtttg atactatgcg
     8281 ttttattatg aaatgattta ctttatctta tcctgaaatg gtgttatttt tgagttatct
     8341 ggcttgactt tcttgatgga aattatataa tagttgtaat aacaataatt acaacgagaa
     8401 aagaggacca tttatgacct atgaatacaa gagtcacatt tatttggcag agacagtttt
     8461 aaatgtaaag gatttggcca gtcaaacagc cttttatcag caagttattg gtttagaaat
     8521 cttatctcaa actgagacag agtccattct aggccttggt ggaaaagtct tggtacagct
     8581 gattcaagca caagagagcg gagaagtgag ggaacattat ggtctttacc atttggccat
     8641 tctcttgccc acacgcaagg ctttagctga tgtcttgaaa cacctgacag atttacaaat
     8701 tcctcttgtc ggcggtgcag accatggtta cagtgaagct atttacttgg aagatttgga
     8761 gggaaatggc attgaactct atcgagataa gccagtttcc acatgggata ttcgagaaga
     8821 tggacgcatt atcggagtga cagaggctct tgcggcgcag gacatttatg agttggggga
     8881 aagagtagag ccctttatcc tggcagaagg tacgagaatg gggcatattc atctttccgt
     8941 caaggatagt cgaaagtcca gccagtttta tcaaaaggtg ttagggctag aggataaatt
     9001 cagtgtgcct agcgctagtt ggattgcggc tggagattac catcatcatt tagcagttaa
     9061 cgaatgggga ggaaaaggtc tggcttcgcg taagcaaggc ttaccaggtt tagcctacta
     9121 tgtcatcgaa gtcgcacaca aaaaagaact gttaacgatt gcccaacgag cacaagaagt
     9181 tgacgcacca atcaaatgga tgacatcgag ccaattggaa atcacagact cagatggcat
     9241 cgtgacccgt attcgtttag caaggtaaaa ttaggaattt ttaataagtt ataagtattg
     9301 ctagtttgct ttttgaacgg tctttggtaa cagaactgcg tgagctggat gggcgagaat
     9361 tttgacaaag aagctgatta gagatataat gaagaaaaat cgagcaagga aaaagaaatg
     9421 acaaattcaa agtatattac ttgtttgaaa cgttcagagg gccagttgtg tgggattcaa
     9481 aagatgattg aaggagatcg tgactgtgct gatattgtga cgcaactgac agcagtgaga
     9541 tctagtgtag agcgcgtgat tgagatgata attaccgaaa atcttactga atgtatcaat
     9601 cagccactag atgattctga agctcaaaag gaacgcctag aaaaggctat ccgatacttg
     9661 attaaacgga aataaatgaa tgttttgaga cgatatgtgc aaaggtctat taactattag
     9721 aatagtttaa tgtgagtcaa aagaagttgt aaaaaatctt taaaattaaa aaaacgcata
     9781 gtatcaggtg ttgaatgtac tgacccccaa aagttagatt ttttctgtct aacttttggg
     9841 gtgcagttca taagaacctt ggtactatgc gttttattat gtagagactt atactcttcg
     9901 aaaatctctt caaaccacgt cagcttcacc ttgccgtaga tatggttact gacttcgtca
     9961 gttctatcca caacctcaaa acagtgtttt gagctgactt cgtcagttcc atccacaacc
    10021 ttaaaacagt gttttgagca gcttgcggct aacttcctag tttgcacttt aattttcatt
    10081 gagtattact tcatcttctc atgaaattga gtttttgccc agctcctctt gattattcta
    10141 cttgaccggg ccaagcattc ataccacctt ctacgttggt aacggtgagg ccttgggagc
    10201 tgagaaattg gcaggtagat gcagagcgga ctcctccttg acaaatgaca tagtattcat
    10261 ggtcaggttt gagttctttg tagccttgct ctaaggtact taatggaaga tttttggcac
    10321 ctggtgcatg tcctgcttgg aattcatgtg cttcacggac atcgataagt tctagatttt
    10381 cattttggta ttttccataa aagtcagcca tgctgatact agtttccata ttctactcct
    10441 tctgggttaa ccattttgta tagtgaataa gcgccgtcaa ggttttgggc ggtaaatcct
    10501 gcttgcttga ggataggctc tgcgatatag ctgcgcaaac cactgtggca gctgacgatg
    10561 taggcttgtt ttttgtccag ttcatcagtt tcctccttga cactttgtca gtttttgata
    10621 caatagtaca aaattagagg aggcaggcta tgattcagaa acatgcgatt cccattttag
    10681 agtttgatga taatcctcag gcggttatca tgcccaatca cgaggggttg gatttgcagt
    10741 tgccaaagaa gtgtgtctat gcttttttag gtgaggagat tgaccgctat gcgagggaag
    10801 taggggcgaa ctgtgttggc gaattcgttt ctgctaccaa gacctatcca gtctatgtta
    10861 tcaactacaa gggtgaggag gtctgtctgg ctcaggctcc tgttggctcc gctccagcag
    10921 cccagtttat ggattggttg attggctatg gtgtggagca gattatctct actgggacct
    10981 gtggtgtcct agctgatata gaggaaaatg cctttctagt ccctgttcgc gctttgcgag
    11041 atgagggagc cagttaccac tatgtggcac cttgtcgtta tatggaaatg cagccagagg
    11101 ctattgctgc tattgaggaa gttttggaag acagagggat tccttatgaa gaagtcatga
    11161 cctggacgac agacggtttt taccgagaaa cggctgaaaa ggtggcttat cgtaaggaag
    11221 aaggctgtgc tgttgtggag atggagtgtt ctgctcttgc ggcagtagct caattgcgtg
    11281 gggttctctg gggtgaattg ttgttcacag cagattctct agcggacttg gaccagtacg
    11341 acagtcgtga ctggggctcg gaagctttta ataaggcgct agaactgagt ttagcaagtg
    11401 ttcaccacct ttagttgtac tggcaaagga tttgttttat cataaaatat ctagctcata
    11461 cttttcaaaa atatgtttaa acgaggtcac cttcctcttg tcctaggcat gttgaggttg
    11521 ggaaaaatct ttaaaatcag aaaaacgtat catatcaggt gatgaaaatt ttgatactat
    11581 gcgttttatg ttggtaagat ttagagtgag atgaaatgat actcttcgaa aatctcttca
    11641 aaccaggtca gcttcacctt gccgtataga tgttactgac ttcgtcagtt ctatctgcaa
    11701 cctcaaaaca gtgttttgag ctgacttcgt cagttctatc tgcaacctca aaacagtgtt
    11761 ttgagcaacc tgtgactagc tttctaatcg atgccttggt tttcattgcc tataatcaaa
    11821 aagagaaatt ttctcctgaa aagcatatag agtagctggc gttaaaagct cctgtcttgc
    11881 ttttttgacc tatagtcata tctatcaagt attgttcttg cctaagctat caataaaaag
    11941 gtggcatttt ttaggcttgg tgttagtgaa ttttgcctta tcctatctaa gtcatttcga
    12001 gctttttatg gtacaatgga aacatgttat tcaaattatc taaggaaaaa atagagctag
    12061 gcttatctcg tttatcgcca gcccgtcgta tttttttgag ttttgccttg gtcattttac
    12121 taggctctct tcttttgagc ttgccctttg tccaagttga aagctcacga gcgacttatt
    12181 ttgatcatct tttcactgct gtctctgcag tctgtgtgac aggtctctca acccttccag
    12241 tagctcacac ctataatatc tggggccaaa taatctgttt gctcttgatt cagatcggtg
    12301 gtctagggct catgaccttt attggggttt tctatatcca gagcaagcaa aagcttagtc
    12361 ttcgtagccg tgcaactatt caggatagtt ttagttatgg agaaactcga tctttgagaa
    12421 agtttgtcta ttctattttt ctcacgacct ttttggttga gagcttggga gctattttgc
    12481 ttagttttcg ccttattcct caacttggct ggggacgtgg tctttttagt tccatttttc
    12541 tagcgatctc agccttctgt aatgccggtt ttgataattt agggagcacc agtttatttg
    12601 cttttcagac cgatttactg gtcaatctgg tgattgcagg cttgattatt acaggcggcc
    12661 ttggttttat ggtctggttt gatttggctg gtcatgtagg aagaaagaaa aaaggacgtc
    12721 tgcactttca tacgaagctt gtattattat tgactatagg tttgttgtta tttggaacgg
    12781 caactactct ctttcttgag tggaacaatg ctggaacgat tggcaatctc cctgttgccg
    12841 ataaggtttt agttagcttt tttcaaacag tgacgatgcg aacagctggc ttttctacga
    12901 tagattatac tcaggctcat cctgtgactc ttttgattta tatcttacag atgtttctag
    12961 gtggggcacc tggaggaaca gctgggggac tcaagattac gacatttttt gtcctcttgg
    13021 tctttgcacg aagtgagctt ctaggcttgc ctcatgccaa tgttgcgaga cgaacgatcg
    13081 cgccgcgaac ggttcaaaaa tcctttagtg tctttattat ctttttgatg agcttcttga
    13141 taggattgat tctgctaggg ataacagcca aaggcaatcc tccctttatc cacctcatat
    13201 ttgaaaccat ttcagctctt agtacagttg gtgtaacggc aaatctgact cctgaccttg
    13261 ggaaattggc tctcagtgtt atcatgccac ttatgtttat gggacgaatt ggtcccttga
    13321 ccttgtttgt tagcttggca gattaccatc cagaaaagaa agatatgatt cactatatga
    13381 aagcagatat tagtattggt taagaaagga aagagcatgt cagatcgtac gattggaatt
    13441 ttgggcttgg gaatttttgg gagcagtgtc ctagctgccc tagccaagca ggatatgaat
    13501 attatcgcta ttgatgacca cgcagagcgc atcaatcagt ttgagccagt tttggcgcgt
    13561 ggagtgattg gtgacatcac agatgaagaa ttattgagat cagcagggat tgatacctgc
    13621 gataccgttg tagtcgcgac aggtgaaaat ctggagtcga gtgtgcttgc ggttatgcac
    13681 tgtaagagtt tgggggtacc gactgttatt gctaaggtca aaagtcagac cgctaagaaa
    13741 gtgctagaaa agattggagc tgactcggtt atctcgccag agtatgaaat ggggcagtct
    13801 ctagcacaga ccattctttt ccataatagt gttgatgtct ttcagttgga taaaaatgtg
    13861 tctatcgtgg agatgaaaat tcctcagtct tgggcaggtc aaagtctgag taaattagac
    13921 ctccgtggca aatacaatct gaatattttg ggtttccgag agcaggaaaa ttccccattg
    13981 gatgttgaat ttggaccaga tgacctcttg aaagcagata cctatatttt ggcagtcatc
    14041 aacaaccagt atttggatac cctagtagca ttgaattcgt aaagagggat gacccctctt
    14101 ttttgatgcc caagatggca aatagagaca gaagcccctt gtcttctagt aaaagttctt
    14161 caaagactgg actttatggt aaaatagaaa gaagtgacaa gagagagtaa tactcaatga
    14221 aaatcaaaga tcaaactagg aaactagcta cgggctgctc aaaacactgt tttgaggttg
    14281 tggatagaac tgacgaagtc agctcaaaac actgttttga ggttgcagat agaactgacg
    14341 aagtcagtaa catctatacg gcaaggcgac gttgacgcgg tttgaagaga ttttcgaaga
    14401 gtataagaaa aaatcagtcc cctaaaggag cagattatga agttattgtc tatcgccatt
    14461 tctagctata atgcagcagc ctatcttcat tactgtgtgg agtcgctagt gattggtggt
    14521 gagcaagttg ggattttgat tatcaatgac gggtctcagg atcagactca ggaaatcgct
    14581 gagtgtttag ctagcaagta tcctaatatc gttagagcca tctatcagaa aaataaatgc
    14641 catggcggtg cggtcaatcg tggcttggca gaggcttctg ggcgctattt taaagtagtt
    14701 gacagtgatg actgggtgga tcctcgtgcc tacttgaaaa ttcttgaaac cttgcaggaa
    14761 cttgagagca agggtcaaga ggtggatgtc tttgtgacca attttgtcta tgaaaaggaa
    14821 gggcagtctc gtaagaagag tatgagttac gattcagtct tgcctgttcg gcagattttt
    14881 ggctgggacc aggtcggaaa tttctccaaa ggccagtata ccatgatgca ctcgctgatt
    14941 tatcggacag ctttgttgcg tgctagccag ttctaattgc ctgaacatac tttttatgtc
    15001 gataatctct ttgtctttac gccccttcag caggtcaaga ccatgtacta tctgcctgtc
    15061 gatttctatc gttatttgat tgggcgtgag gaccagtctg tcaatgagca agtgatgatt
    15121 aagtgcattg accagcaact caaggtcaat cgactcttgg tagaccagct tgatttgtcc
    15181 caagtgagtc atcctaaaat gcgagaatat ctgctgaatc atattgaaat cacgacggtg
    15241 atttccagta ccctgctcaa ccgatctgaa acagcggagc atctggcaaa aaaacgccaa
    15301 ttgtggacct atattcagca ggaaaatcca aaagtctttc aggctattcg taagaccatg
    15361 ttgagccgtt tgaccaaaca ttctgtcttg ccagatcgca aactgtccaa tgtcgtctat
    15421 caaatcacca aatctgttta tggatttaat taatataagt gttttataag agggatttaa
    15481 gaaaaatttt aactttttct tagtcctttt taatttcagg agattatact agagtcatca
    15541 aataaagaaa gactctaagg agaatcctat gaaattcaat ccaaatcaaa gatatactcg
    15601 ttggtctatt cgccgtctca gtgtcggtgt tgcctcagtt gttgtggcta gtggcttctt
    15661 tgtcctagtt ggtcagccaa gttctgtacg tgccgatgtg gtcaatccga ccccaggtca
    15721 agtcttacct gaagagacat cgggaacgaa agagggtgac ttatcagaaa aaccaggaga
    15781 caccgttctc actcaagcga aacctgaggg cgttactgga aatacgaatt cacttccgac
    15841 acctacagaa agaactgaag tgagcgagga aacaaactct tctagtctgg atacactttt
    15901 tgaaaaagat gaagaagctc aagaaaatcc agagctaaca gatgccttaa aagaaactgt
    15961 agatacagct gatgtggatg ggacacaagc aagtccagca gaaactactc ctgaacaagt
    16021 aaaaggtgga gtgaaagaaa atacaaaaga cagcatcgat gttcctgctg cttatcttga
    16081 aaaagctgaa gggaaaggtc ctttcactgc cggtgtaaac caagtaattc cttatgaact
    16141 attcgctggt gatggtatgt taactcgtct attactaaaa gcttcggata atgctccttg
    16201 gtctgacaat ggtactgcta aaaatcctgc tttacctcct cttgaaggat taacaaaagg
    16261 gaaatacttc tatgaagtag acttaaatgg caatactgtt ggtaaacaag gtcaagcttt
    16321 aattgatcaa cttcgcgcta atggtactca aacttataaa gctactgtta aagtttacgg
    16381 aaataaagac ggtaaagctg acttgactaa tctagttgct actaaaaatg tagacatcaa
    16441 catcaatgga ttagttgcta aagaaactgt cgaaaaagct gttaaagata acgttaaaga
    16501 cagtatcgat gttccagcag cctacctaga aaa
//
LOCUS       DAVHSY010000042        16438 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.043, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000042 DAVHSY010000000
VERSION     DAVHSY010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.043"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            58..532
                     /locus_tag="VVR43_001678"
                     /pseudo
     CDS             58..532
                     /locus_tag="VVR43_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730798.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
     gene            814..1061
                     /locus_tag="VVR43_001679"
                     /pseudo
     CDS             814..1061
                     /locus_tag="VVR43_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
     gene            1166..1468
                     /locus_tag="VVR43_001680"
                     /pseudo
     CDS             1166..1468
                     /locus_tag="VVR43_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1624..2853
                     /locus_tag="VVR43_001681"
     CDS             1624..2853
                     /locus_tag="VVR43_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU6150008.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2873..5569
                     /gene="ppc"
                     /locus_tag="VVR43_001682"
     CDS             2873..5569
                     /gene="ppc"
                     /locus_tag="VVR43_001682"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU6150009.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITHKKSDTNTPNRYEAIMDQVVDRS
                     YDVYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5652..5869
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5982..6986
                     /locus_tag="VVR43_001683"
     CDS             5982..6986
                     /locus_tag="VVR43_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6150010.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            7055..7921
                     /locus_tag="VVR43_001684"
     CDS             7055..7921
                     /locus_tag="VVR43_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6150011.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGHMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            7918..8676
                     /locus_tag="VVR43_001685"
     CDS             7918..8676
                     /locus_tag="VVR43_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6150012.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTISLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLFPRRLASYKDKFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRVIQDLKQEEKAKMKISDYYQLFE"
     gene            8766..10526
                     /gene="dnaG"
                     /locus_tag="VVR43_001686"
     CDS             8766..10526
                     /gene="dnaG"
                     /locus_tag="VVR43_001686"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU6150013.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYQAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10529..11638
                     /gene="rpoD"
                     /locus_tag="VVR43_001687"
     CDS             10529..11638
                     /gene="rpoD"
                     /locus_tag="VVR43_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU6150014.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11652..11981
                     /locus_tag="VVR43_001688"
     CDS             11652..11981
                     /locus_tag="VVR43_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU6150015.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            12096..13139
                     /gene="cpoA"
                     /locus_tag="VVR43_001689"
     CDS             12096..13139
                     /gene="cpoA"
                     /locus_tag="VVR43_001689"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU6150016.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            13155..14480
                     /locus_tag="VVR43_001690"
     CDS             13155..14480
                     /locus_tag="VVR43_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU6150017.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14511..14687
                     /locus_tag="VVR43_001691"
     CDS             14511..14687
                     /locus_tag="VVR43_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU6150018.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            14746..14880
                     /locus_tag="VVR43_001692"
     CDS             14746..14880
                     /locus_tag="VVR43_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU6150019.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            14944..16254
                     /gene="obgE"
                     /locus_tag="VVR43_001693"
     CDS             14944..16254
                     /gene="obgE"
                     /locus_tag="VVR43_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU6150020.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            16264..16422
                     /locus_tag="VVR43_001694"
     CDS             16264..16422
                     /locus_tag="VVR43_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150021.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT         5091 a         2822 c         3667 g         4858 t
ORIGIN      
        1 accaagatta aaagaattat catttttaca gtttttcgag aaaattggga accgtacatg
       61 aaaaagtaca cggaagtttt tcaaagtcaa tttcctaatc taaacattga ttacttgctc
      121 ctggacactg agcagattga tcttgatagc tatctagatg ctgacataat tatcatcggt
      181 ggtggaaata cggaaaaata tattgctaac ttatgttaat caggagttca aaagttatat
      241 cgatcatatg cttaataaag aggcaaaaat tataggattt tctgcaggag ccctactatt
      301 aggagaaaaa gtctatgtct cacctaatga taattcagat catcagataa agataaaaaa
      361 tggattagga ctctttagtc agtttttaat tagtgtccat tatgattcct ggaatgataa
      421 agcaaataag gatagagctg aagaactcgt taatgttccc ataattccac taaatgatca
      481 ttcttgtctt gtattggata aacttggaaa catcatagag aaaattgact aactttcata
      541 atgtaaaaat ggatctagga aataaaagtg tagacgaact ggataggtta ctagtgaaaa
      601 ctgcaaaaag tgttgtaaag tgaatcggag tgtgcttgat ggattttagt agtaagatag
      661 ccataaataa aggctggtca gatgataaaa aatattgtgt gacagatcaa aatcagtaaa
      721 aatatttctt gcgtgtttct gataagtcga agttagatta taaaaaaatt tgaatttgat
      781 atgatggaga aagtagcttc tcttggagtt ccgatgtgta aaccaattag cattgaactc
      841 tgcgatgacg aagtacattc tttacacgaa tggatagacg gaagagatgc aatagatagc
      901 attttagctt attcagaaaa ccaacaatac acatatggtg tagaagcagg aaagatactt
      961 agaaagattc atacaattcc tgctacagaa gtttgtgaag attgggaaat ttttttaatc
     1021 taaaaattga tgataaaatc tccaacgaaa tgatatggta agtccgaaac gctcagtgtg
     1081 taagcttgtt gctaaaagcg taaaaacctt ggaacgaaag gaataataga cttcctgcga
     1141 aacaaaaata caatacaata aaactatgga tgatgaagca agtaaacaat taagcgatag
     1201 ccgtttcaag atccttgtag gtgttcagcg cacgactttt gaagagatgt tagctgtgtt
     1261 aaaaacagct tatcaacgta aacgcgcaaa aggtggacga aaaagcaaat taagcctaga
     1321 cgatctcctt atggtaacta ttcaatacat gcgagaatag agcacttatg aacaaattgc
     1381 ggctgatttt ggcattcacg aaagcaactt aatccgtcgg agtcaatggg ttgaagcaac
     1441 tcttattcaa aatggtttta cgatttcaaa ttctgcctta attctgtaaa aacagtaaaa
     1501 ttcgaaggat tgtaaggtaa gagttttttt ctttctgaaa aaatggtata atagcaatca
     1561 aaactagaaa ataaaacgga atttggaaca gatttgtctg tatcctagta gagtggtgat
     1621 actatgaaga ttagtaagag gcacttatta aattattcca tcttgattcc ctacttgctt
     1681 ttatctattt tgggcttgat tgtggtctat tcgaccacca gtgctatttt aattgaagaa
     1741 ggcaagagcg ccttgcagtt ggttcgaaac caaggaatct tttggattgt tagtttgata
     1801 ctgattgcct taatttataa attgagacta gattttttga gaaatgagcg actaatcatt
     1861 ttagttatat taatagaaat gcttttattg ttcttggctc gttttattgg tatttcagta
     1921 aacggggcat acggttggat ttcggttgca ggagtaacta ttcagccagc tgagtactta
     1981 aaaatcatta ttatttggta tttagctcac cgattctcca aacagcaaga agaaatagct
     2041 acttatgatt ttcaagtttt gactcaaaat caatggcttc cccgtgcttt taatgattgg
     2101 cgattcgttc tcctagttct gattggaagt ttgggaattt tccctgattt aggaaatgcg
     2161 actattttag tcttggtttc cttgattatg tatacagtta gtggaatcgc ttatcgctgg
     2221 ttttcaacca ttctggcgct cgtatctgcc acttctgtct ttgtcttgac cactatcagc
     2281 ctaatcggtg ttgagacctt ttcaaaaatt ccagtatttg gctatgtagc caagcgcttt
     2341 agtgcctttt ttaatccttt tgccgatcgt gctgatgcag gtcaccagtt agctaattct
     2401 tattttgcca tggtcaatgg tggttggttt ggtctaggtc ttggaaactc gattgaaaaa
     2461 cgaggttatt tgccagaagc tcatacagac tttgtctttt ctatcgtgat tgaagaattt
     2521 ggctttgttg gtgccagtct tattttagct ctcttgtttt tcatgatttt gcggattatc
     2581 ttggtcggta tccgagcgga gaatcctttc aatgccatgg ttgcactcgg tgtcggaggg
     2641 atgatgttgg ttcaggtatt tgtcaatatc ggagggattt cgggcttgat tccatctaca
     2701 ggagtgactt tccctttctt atcccagggt ggaaatagtc ttctagtctt atcagtggca
     2761 gtagcctttg tcttaaatat tgatgccagt gaaaaacgcg ctaagttgta ccgagaattg
     2821 gaaaatcaac caatgaacct tctgttgaag taggataaag aaaggatagt ttatgtctct
     2881 tcaaaaatta gaaaattata gtaataaaag tgttgtgcaa gaagaagtct tgattctaac
     2941 agaattactg gaagatatta ctaaaaatat gcttgcccca gagacctttg aaaaaataat
     3001 acagttgaaa gaattatcaa cgcaggaaga ttatcaaggt ctaaaccgtc tagtgactag
     3061 cttatcaaat gatgaaatgg tctatatttc acgctatttc tctatcttac ctcttttgat
     3121 taatatttca gaggatgtgg atttagctta tgaaatcaat catcaaaata atattgatca
     3181 ggactattta ggtaaattat ctacaacgat taaattggta gcagaaaagg aaaatgccgt
     3241 tgagatccta gaacacttga atgttgtccc tgttttgaca gcccatccaa cacaagtgca
     3301 acgcaaaagt atgttggatt taacaaatca tattcatagt cttttgcgta aataccgtga
     3361 tgttaagttg gggttgatca ataaagataa atggtacaat gatttgcgtc gttacatcga
     3421 aattatcatg cagacagaca tgattcgtga gaaaaaatta aaagtgacta acgaaatcac
     3481 gaatgctatg gaatattata acagctcctt tttgaaagct gtacctcatt tgacgacgga
     3541 gtataagcgc ttagcgcaag cgcatggtct gaatttaaaa caggctaaac caatcaccat
     3601 gggtatgtgg ataggtggtg accgtgatgg aaatccattt gttacagcaa agaccttgaa
     3661 gcagtctgca ctcactcagt gtgaagtcat catgaactac tatgataaaa agatttacca
     3721 actttatcgt gaattttctc tttcaactag cattgtcaac gtcagcaagc aagtcagaga
     3781 aatggctcgt caatccaagg ataactcgat ttaccgcgaa aaagagcttt accgtcgtgc
     3841 cttgtttgat attcaatcaa aaattcaggc aactaaaacc tatctgattg aggatgaaga
     3901 agttgggact cgttatgaaa ccgccaatga tttctacaag gatttgattg ccattcgaga
     3961 ttctctacta gaaaataagg gcgagtcctt gatttcaggt gattttgtgg aattattgca
     4021 ggcagtagag atatttggtt tttacttagc atcaattgat atgcgacaag actctagcgt
     4081 ctatgaagcc tgtgtggcag aactcttgaa atcagcagga attcattctc gttatagcga
     4141 gttgagcgaa gaagaaaagt gtgaccttct cttgaaagaa ttagaagaag atccccgaat
     4201 tctttctgcg actcacgcag aaaaatcaga attattagca aaagaattag ctatttttaa
     4261 gacggctcgt gttttgaaag ataagttggg agatgatgtc atccgtcaga ccatcatttc
     4321 acatgcaacc agcctttctg atatgctaga attagctatt ctgttaaaag aagtaggact
     4381 ggtggatacg gaaagggcgc gtgttcagat tgttcccctt tttgaaacaa ttgaagactt
     4441 ggatcattca gaggaaacaa tgagaaaata tctttctctt agccttgcca aaaaatggat
     4501 tgactcacga aataactacc aagaaatcat gcttggctac tctgacagta ataaagatgg
     4561 cggttacttg tcatcatgtt ggaccctcta caaggctcaa caacaattga ctgctattgg
     4621 agatgaattt ggcgttaagg ttaccttctt ccatggtcgt ggtggtactg tcggtcgtgg
     4681 tggtgggcca acctatgaag ccattacatc tcaaccgctc aagtctatca aggatcgtat
     4741 ccgtttgacg gagcagggtg aagtaattgg gaataaatac ggtaacaaag acgccgctta
     4801 ctataacctt gaaatgctag tatctgcagc tattaaccgt atgattactc ataagaagag
     4861 tgataccaat accccaaatc gttatgaagc cattatggat caagtagtgg accgtagtta
     4921 cgatgtctac cgtgatttgg tctttggtaa tgagcatttc tatgattatt tcttcgagtc
     4981 aagtccaatc aaggctattt caagttttaa tattggttct cgtccagccg ctcgtaagac
     5041 tattactgaa atcggtggtt tgcgtgccat cccttgggta ttctcatggt cacagagtcg
     5101 tgttatgttc cctggatggt acggggttgg ttcaagcttc aaggaattta tcaataaaaa
     5161 tccagagaat attgctatct tacgagatat gtaccaaaat tggcctttct tccaatcgct
     5221 tctttcaaat gttgatatgg ttttgtcaaa atcaaatatg aatattgctt ttgaatatgc
     5281 taaactttgt gaagacgagc aagttaaggc catctatgag actattttaa atgaatggca
     5341 agttactaag aacgttatct tggctattga aggacatgac gaactcttag ctgacaatcc
     5401 atatctaaaa gctagtctgg attaccgtat gccttacttt aatattctca actatattca
     5461 gttagagttg attaaacgcc aacgtcgtgg agaattgtcc agtgatcaag aacgattgat
     5521 tcatatcacc atcaacggaa ttgcgacagg attgcgtaat tcaggttgat aattttcaag
     5581 agtgaatgct aaaagtgaat atcaaaaaaa ttctaataga ctattgacaa gtagtttaaa
     5641 aatgatataa tttaaccatt cagaaaagta atcatacaaa ctttttagag agtctgtggt
     5701 agctgaaaac agataagtgg caatgatgaa aattgggctg aatgctattt agaatttgaa
     5761 attataaaaa ttcggtaagc acaccttaca gtgcatctcg ttattgcgag actgagcgat
     5821 agggaaattc cctataattg aggtggtacc gcgcatcgac gtcctcacac aagttttttg
     5881 tgtgaggatt tttttgatgg aggttagtat ggaaagaaaa caatggcgtc gcttgtttag
     5941 ataagtgaaa tatgttaaag gaaataaaaa ggagaaacag aatgaaaaat aaacgtttaa
     6001 ttggaattat tgctgcatta gcagtcttag tagcaggaag cttgatttat tcttcaatga
     6061 ataaatcaga agctcagaat aataaggatg agaagaaaat aaccaagatt ggtgtgcttc
     6121 aatttgtgag ccatccatcc cttgatttga tttataaagg gatccaagat ggacttgcag
     6181 aagaaggata taaagatgat caagttaaaa ttgattttat gaactcagaa ggtgaccaaa
     6241 gtaaggttgc gacaatgagt aaacaattgg ttgcaaatgg gaatgacctt gtggttggta
     6301 tcgcaacacc agcagcccaa gggttggcta gtgcaacaaa agacctaccg gttatcatgg
     6361 ccgctattac agacccaatt ggtgctaact tggttaaaga tttgaaaaaa ccaggtggca
     6421 acgttacagg ggtatctgac cacaatccag ctcaacaaca agttgaactc atcaaggctc
     6481 tgacaccgaa tgtgaaaaca atcggagctc tttactcaag tagcgaagac aattcaaaaa
     6541 cacaggtcga agaatttaag gcttatgctg aaaaagcagg tctgacagtg gaaacatttg
     6601 cagttccttc aacaaatgaa attgcctcaa ctgtcactgt tatgactagc aaggtagatg
     6661 ctatttgggt tccaattgat aacaccattg catcaggatt tccaacggtt gtctctagca
     6721 atcaaagttc taagaaacca atttatccca gtgcgacagc tatggtagaa gtaggtggtt
     6781 tggcatcagt tgtaattgac caacatgacc ttggtgtggc aacaggtaaa atgattgtgc
     6841 aagtcttgaa aggtgcaaaa ccagccgata ccccagtcaa tgtcttttca actggtaagt
     6901 cagtcatcaa taaaaaaata gcacaagaac taggtattac tattcctgag tctgttctca
     6961 aagaagcagg acaagtcatc gaataaataa ggtagggagg aggagactct tcccattttt
     7021 taaaaagatg aatatagaaa ggattaaata aaatatgatt gtttccatta tttctcaagg
     7081 atttgtctgg gctattctag gtctgggaat ctttatgaca tttaggattt taaactttcc
     7141 agatatgacg acagaaggtt ccttccctct tgggggagct gttgctgtca ctttgataac
     7201 caaaggcgtg aacccatttt tagcgacact tgttgctgta ggagcaggtt gtttggctgg
     7261 aatggcagca ggccttcttt atacaaaagg gaagatccca accttgctct cagggatttt
     7321 ggtgatgact tcttgtcact caatcatgct cttgattatg ggacgtgcga atttaggcct
     7381 gcttggaacc aagcaaattc aggatgtttt gccttttgat tcggatttga atcaactctt
     7441 gacaggtctc atctttgtga gtattgttat tgctctcatg ctctttttct tggacactaa
     7501 actcggacaa gcctatattg ctacagggga taatcctgat atggctagaa gtttcgggat
     7561 tcatactgga cacatggagc tcatgggctt ggtcttatca aatggtgtga ttgcccttgc
     7621 aggtgccctc attgctcagc aagaaggtta tgccgatgtg tctcgaggga tcggggttat
     7681 cgttgtgggg cttgcaagtt tgattattgg agaagttatt ttcaagagtt tgagcttggc
     7741 agagcgtttg gttactatcg ttgtaggttc tatcgcttat caatttttag tgtgggcagt
     7801 tatcgcactt ggctttaata caagttacct tcgtttatac agtgccttga ttttagcagt
     7861 ctgcctcatg attccaacat ttaagcaaac aatcttgaaa ggagccaagt taagcaaatg
     7921 acagcaattg tagaattaaa aaatgcaacc aaaatcgtta aaaatggctt tgatgaagaa
     7981 aagattattt taaatgatgt ttccttagaa atttttgaac aggactttat cacgattttg
     8041 ggtggaaatg gtgctggtaa atcaaccctc tttaacacta ttgcaggaac catatcacta
     8101 accagtggaa ctatccgtat tttaggtgag gatgttacca agttttcacc agagaagcgc
     8161 gctaagtatc tgtctcgagt cttccaagat ccaaagatgg ggacagctcc tcgtatgaca
     8221 gtggcagaga atctcctgat tgccaagttt cgtggtgaaa agcgtggact atttccgaga
     8281 cgtctggcta gctataagga taagtttcag gcgaccattg aaaaagtggg aaacggtctt
     8341 gagaaacact tgaatacacc gattgagttc ttatctggtg gacaaagaca ggctttgagt
     8401 ctcttgatgg caaccttgaa gcgacctgaa ttactcttgt tagacgagca tactgctgcc
     8461 ctggatccaa agactagtgt tgctttgatg gaattgacag atgaatttgt taagaaagat
     8521 caattgacag cccttatgat tacccatcat atggaagatg ctctcaaata tggcaatcgc
     8581 ttgattgtca tgaaagaagg acgggttatc caagatttga aacaagaaga aaaagcaaaa
     8641 atgaaaatct ctgattatta tcaactcttt gaataaagta gggaaaatga gtgaaatggt
     8701 ttactttttt tctgaaataa agtatactat ataaagtaaa ctatgataac atggaggtat
     8761 tgtgtatggt tgacaaacaa gtcattgaag aaatcaaaaa caatgccaac attgtggaag
     8821 tcataggaga tgtgatttct ttacaaaagg caggacggaa ctatctaggg ctctgtcctt
     8881 ttcatggtga aaaaacacct tctttcaacg ttgtagagga caagcagttt taccactgtt
     8941 ttggttgtgg tcgctcaggt gatgtcttta aattcatcga ggagtaccaa ggggttacct
     9001 ttatggaggc tgtccaaatc ttaggtcagc gtgtcgggat tgaggttgaa aaaccgcttt
     9061 atagtgaaca gaagccagcc tcgcctcacc aagctcttta tgatatgcac gaagatgcgg
     9121 ctaaatttta ccatgctatt ctcatgacaa cgactatggg cgaagaggcc agaaattacc
     9181 tttatcagcg gggtttgaca gatgaagtgc ttaaacattt ttggattggt ttagcacctc
     9241 cagaacgaaa ctatctctat caacgtttgt ctgatcagta tcgtgaagaa gatttactgg
     9301 attcaggcct gttttatctc tcggatgcca atcaatttgt agacaccttt cacaatcgca
     9361 ttatgtttcc cctgacaaat gaccaaggaa aggtcattgc cttctcaggt cgtatctggc
     9421 aaaaaacaga ttcacaaact tctaagtata aaaacagccg atcgactgca atttttaaca
     9481 aaagttacga attatatcat atggataggg caaaaaaatc ttctggaaaa actagtgaga
     9541 tttacctgat ggaaggattc atggatgtta ttgcagccta tcaggctgga atcgaaaatg
     9601 ctgtggcgtc gatgggaacg gccttgagtc gagagcatgt tgagcatctg aaaaggttaa
     9661 ccaagaaatt ggttcttgtt tacgatggag ataaggctgg gcaagccgcg atattgaaag
     9721 cattggatga aattggtgat atgcctgtgc aaatcgttag catgcctgat aacttggatc
     9781 ctgatgagta tctacaaaaa aatggtccag aagacttggc ctatctatta acgaaaactc
     9841 gtattagtcc gattgagttc tacattcatc agtacaaacc tgaaaacagt gaaaatctgc
     9901 aggctcagat tgagtttatt gaaaaaatag ctcccttgat tgttcaagaa aagtccatcg
     9961 ctgctcaaaa cagctatatt catattttag ctgacagtct ggcgtccttt gattatgccc
    10021 agattgagca gattgttaat gagagtcgtc aggtgcaaag gcagaatcgc atggaaggaa
    10081 tttccagacc gacgccaatc accatgccta tcaccaagca gttatcggct attatgaggg
    10141 cagaagccca tctactctat cggatgatgg aatcccctct tgttttgaac gattaccgtt
    10201 tgcgagaaga ctttgcattt gctacacctg aatttcaggt cttatatgac ttgcttggcc
    10261 agtatggaaa tcttcctcca gaagttttag cagagcagac agaggaagtt gaaagagctt
    10321 ggtaccaagt tttagctcag gatttgcctg ctgagatatc gccgcaggaa cttagtgaag
    10381 tagagatgac tcgaaacaag gctctcttga atcaggacaa tatgagaatc aaaaagaagg
    10441 tgcaggaagc tagccatgta ggagatacag atacagccct agaagaattg gaacgtttaa
    10501 tttcccaaaa gagaagaatg gagtaataat ggcaacaaaa caaaaagaag taacaacatt
    10561 tgacgtacag gtagcagaat ttatccgtaa tcataagcaa aaagggacag caacagatga
    10621 tgaaatcaat gcaagtctgg ttattccttt taccttggac gctgatggga ttgaagatct
    10681 cttgcaacgg attcaggatg caggcatttc tatcacagat aacgaaggaa atccaagtgc
    10741 gcgtgttctt agcaatgaag aagaaccaga actcagcgat gaggacttga ttgggtcaac
    10801 ttctgctaag gtcaatgacc ctgtccgtat gtacttgaaa gaaatagggg tcgttcctct
    10861 cttgaccaat gaagaggaga aagagttggc actggctgtt gaagctggcg atatcgaagc
    10921 taaacaacgt cttgcggaag ccaatcttcg tttggttgtt tccattgcca aacgctatgt
    10981 cggtcgtggc atgcagttcc ttgacttgat tcaagaagga aatatgggct tgatgaaggc
    11041 ggttgacaag tttgactatt ctaaagggtt caagttttca acttatgcaa cttggtggat
    11101 tcgtcaggct atcactcgtg ctattgcgga tcaagctcgt accatccgta tcccagttca
    11161 catggttgaa actatcaata aattggttcg tgaacagcgg aatctccttc aagaattggg
    11221 gcaagatccg acaccagaac agattgctga acgaatggat atgacacctg ataaggttcg
    11281 tgaaatcttg aagattgccc aagaaccagt atctcttgaa actcctatcg gtgaagagga
    11341 cgatagccac cttggagact ttatcgaaga tgaagtgatt gaaaatccag tggattatac
    11401 gactcgtatc gtcttgcgtg agcaattgga tgaaatctta gatactctta cagaccgtga
    11461 agaaaatgtt ctgcgtctac gttttggact agatgatgga aaaatgcgca cacttgaaga
    11521 tgtggggaaa gtctttaacg taactcgtga gcgtatccgt cagattgaag caaaggcttt
    11581 gagaaaacta cgccaaccaa gtcgcagcaa accgcttcgt gattttattg aagactaaga
    11641 gtgaggaaaa tatggcttat acagaagagc aaattgaaaa catcaaaaca cggattttaa
    11701 cagccttgga agaagtcatc gaccctgagt tgggaatcga tattgtcaat cttggtttga
    11761 tctatgagat tcgttttgac ggtgacacag ggcaaacaga gattgacatg actttgacaa
    11821 ctatgggttg tcccttagca gaccttttga cagaccagat ttatgatgct atgatagagg
    11881 ttccagaagt aacggatact gaggttaaat tagtctggta tccagcctgg acagttgaaa
    11941 aaatgagtcg ctatgcccgc attgccctag gcattaagta aacatataaa agcatgtgag
    12001 agactgttgg aaaagcgagg aaatttcccc tcttttcctc tagtctctcc tttcttttgc
    12061 tgattttatt caaagaaaat gatataatag tagttatgga gaaaaagaaa ttacgcatca
    12121 atatgttgag ttcaagtgag aaagtagcag gacagggagt ttcaggtgct taccgtgaat
    12181 tagttcgtct tcttcaccgt gctgccaagg accaattgat tgttacagaa aatcttccga
    12241 tcgaggcaga tgtgactcac tttcatacga ttgattttcc ctattattta tcaaccttcc
    12301 aaaagaaacg ctcagggaga aagattggct atgtgcattt cttgccagct acacttgagg
    12361 gaagtttgaa aattccattt ttcttaaagg gaattgtgaa acgctatgta ttttcttttt
    12421 acaaccggat ggagcacttg gttgtggtca atcctatgtt tattgaggat ttggtagcag
    12481 ctggtattcc acgtgaaaaa gtgacctata ttcctaactt tgtcaacaag gaaaaatggc
    12541 atcctctacc acaagaagag gtagtcagac tgcgcacaga tcttggtctt agtgacaatc
    12601 agtttatcgt agtaggtgct gggcaagttc agaaacgtaa agggattgat gactttatcc
    12661 gtctggctga ggaattgcct cagattacct ttatctgggc tggtggcttc tcttttggtg
    12721 gtatgacaga tggttatgaa cactataaga aaattatgga aaatccccct aaaaatttga
    12781 tttttccagg cattgtatcg ccagagcgga tgcgcgaatt gtatgctcta gcggatcttt
    12841 tcttgttgcc tagttacaat gagctctttc ctatgactat tttagaagct gcgagttgtg
    12901 aggctcctat tatgttgcgt gatttagatc tctataaggt gattttggag ggaaattatc
    12961 gggcgacagc gggtagagaa gagatgaaag aggctatttt ggaatatcaa gcaaatcctg
    13021 ctgccttaaa agatctcaaa gaaaaggcta agaatatttc cagagagtat tctgaagagc
    13081 atctgttaca aatctggttg gacttttatg agaaacaagc cgctttaggg agaaagtaaa
    13141 aagtgaggta atctatgcga attggtttat ttacagatac ctattttcct caggtttctg
    13201 gtgttgcgac cagtattcga accttgaaaa cagaacttga aaagcaggga catgctgttt
    13261 ttatctttac gacgacagat aaggatgtca atcgctacga agattggcaa attatccgca
    13321 ttccaagtgt tcctttcttt gcttttaagg atcgtcgctt tgcctaccga ggttttagca
    13381 aggcacttga aattgctaaa cagtatcagc tagatattat ccatactcag acagaatttt
    13441 ctcttggcct gttggggatt tggattgcgc gtgaattgaa aattccagtc atccatacct
    13501 atcacaccca gtatgaagac tatgtccatt atattgctaa ggggatgttg atccgaccga
    13561 gtatggtcaa gtatctggtt agaggtttcc tgcatgatgt ggatggggtt atttgcccta
    13621 gtgagattgt ccgtgacttg ctatctgatt ataaggtcaa ggttgaaaaa cgggtcattc
    13681 ctactgggat tgaattagcc aagtttgagc gtccggaaat caagcaggaa aatttgaaag
    13741 aactgcgtag taaactaggg attcaagatg gtgaaaagac gttgcttagt ctttcgagaa
    13801 tctcctatga aaaaaatatt caagcagttt tagtagcctt tgctgatgtt ctgaaagagg
    13861 aagacaaggt taaactggta gtagctgggg atggccctta tctgaatgac ctcaaagagc
    13921 aagcccagaa cctagagatt caagactcag tcatctttac agggatgatt gctcctagtg
    13981 agacggctct ttactataaa gcggcggatt ttttcatttc ggcatcgaca agcgaaacgc
    14041 aaggtttgac ctacttggaa agcttagcca gtggaacacc tgtcattgct cacggaaatc
    14101 cttatttgaa caacctcatc agtgataaaa tgtttggaac cttgtactat ggagaacatg
    14161 atttggctgg tgctattttg gaagccctga ttgcaacacc agacatgaac gagcatacct
    14221 tatcagagaa attgtatgag atttcagctg agaactttgg gaaacgagtg catgagtttt
    14281 atctggatgc cattatttca aataacttcc agaaagattt ggctaaagat gatacggtca
    14341 gtcagcgtat ctttaagaca gttttgtatc ttcagcaaca ggtggttgct gtacctgtaa
    14401 aaggatctag acgcatgttg aaggcttcaa aaacacagtt gatcagtatg agagactatt
    14461 ggaaagacca tgaagaatag aaagaggaac agctatgaaa aaaacaatta atgagaagcg
    14521 gtcgtgataa aaagattgcg ggtgtttgtg ctggggtggc ccattatctg gatatggatc
    14581 cgactatcgt tcaagtcatt tggggtgttc ttacttgctg ttacggagct ggaattgtag
    14641 cttacattat tttatggatt atcgcaccag tagcaactga ctattgaaaa ctagctcaat
    14701 tcatgctaag ataatagaaa atagaatgta acgaaggaga gaaaaatggc atttggagat
    14761 aatggaaatc gtaaaaaaac tatgtttgag aaaataacct tgtttatcgt gattatcatg
    14821 ctagtagcaa gtttattggg aatttttgca actgcaattg gtgccctcag taatctataa
    14881 aatagattca agaaaattta gtgactggga tttcccagcc cttttttaaa gtgagaagaa
    14941 ataatgagta tgtttttaga tacagctaag attaaggtca aggctggtaa tggtggcgat
    15001 ggtatggttg cctttcgtcg tgaaaaatat gtccctaatg gaggcccttg gggtggtgat
    15061 ggtggtcgtg gaggcaatgt ggtcttcgtt gtagacgaag gactacgtac cttgatggat
    15121 ttccgctaca atcgtcattt caaggctgat tctggtgaaa aagggatgac caaagggatg
    15181 catggtcgtg gtgctgagga ccttagagtt cgagtaccac aaggtacgac tgttcgtgat
    15241 gcggagactg gcaaggtttt aacagatttg attgaacatg ggcaagaatt tatcgttgcc
    15301 cacggtggtc gtggtggacg tggaaatatt cgtttcgcga caccaaaaaa tcctgcaccg
    15361 gaaatctctg aaaatggaga accaggtcag gaacgtgagt tacaattgga actaaaaatc
    15421 ttggcagatg tcggtttagt aggattccca tctgtaggga agtcaacact tttaagtgtt
    15481 attacctcag ctaagcctaa aattggtgcc taccacttta ccactattgt accaaattta
    15541 ggtatggttc gcacccaatc aggtgaatcc tttgcagtag ccgacttgcc aggtttgatt
    15601 gaaggggcta gtcaaggtgt tggtttggga actcagtttc tccgtcacat cgagcgtaca
    15661 cgtgttatcc ttcacatcat tgatatgtca gctagcgaag gccgtgatcc atatgaggat
    15721 tacctagcta tcaataaaga gctggagtct tacaatcttc gcctcatgga gcgtccacag
    15781 attattgtag ctaataagat ggatatgcct gagagtcagg aaaatcttga agaatttaag
    15841 aaaaaattgt ctgaaaatta tgatgaattt gaagagttac cagctatctt cccaatttct
    15901 ggattgacca agcaaggtct ggcaacactt ttagatgcta cagctgaatt gttagacaag
    15961 acaccagaat ttttgctcta cgacgagtcc gatatggaag aagaagctta ctatggattt
    16021 gacgaagaag aaaaagcctt tgaaattagt cgtgatgacg atgcgacatg ggtactttct
    16081 ggtgaaaaac tcatgaaact ctttaatatg accaactttg atcgtgatga atctgtcatg
    16141 aaatttgccc gtcagcttcg tggtatgggg gttgatgaag cccttcgtgc gcgtggagct
    16201 aaagatgggg atttggtccg cattggtaaa tttgagtttg aatttgtaga ctaggagact
    16261 ggtatgggag ataaaccgat atctttccga gatgcggatg gtaattttgt ttccgccgca
    16321 gacgtttgga atgaaaagaa attggaagaa ctatttaatc gtctcaatcc aaatcgtgcc
    16381 ttgagattgg cacgaactaa aaaggaaaat ccatctcagt aaagaagcta aaaaatcc
//
LOCUS       DAVHSY010000043        14589 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.044, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000043 DAVHSY010000000
VERSION     DAVHSY010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14589
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.044"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            73..1074
                     /locus_tag="VVR43_001695"
     CDS             73..1074
                     /locus_tag="VVR43_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6150022.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            1676..1756
                     /locus_tag="VVR43_001696"
                     /pseudo
     CDS             1676..1756
                     /locus_tag="VVR43_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            2395..3756
                     /gene="trpE"
                     /locus_tag="VVR43_001697"
     CDS             2395..3756
                     /gene="trpE"
                     /locus_tag="VVR43_001697"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU6150023.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPIFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAVGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPQKFEEMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            3753..4319
                     /locus_tag="VVR43_001698"
     CDS             3753..4319
                     /locus_tag="VVR43_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU6150024.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            4330..5334
                     /gene="trpD"
                     /locus_tag="VVR43_001699"
     CDS             4330..5334
                     /gene="trpD"
                     /locus_tag="VVR43_001699"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU6150025.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            5331..6098
                     /gene="trpC"
                     /locus_tag="VVR43_001700"
     CDS             5331..6098
                     /gene="trpC"
                     /locus_tag="VVR43_001700"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU6150026.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            6085..6684
                     /locus_tag="VVR43_001701"
     CDS             6085..6684
                     /locus_tag="VVR43_001701"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU6150027.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTELAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            6662..7885
                     /gene="trpB"
                     /locus_tag="VVR43_001702"
     CDS             6662..7885
                     /gene="trpB"
                     /locus_tag="VVR43_001702"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU6150028.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            7878..8654
                     /locus_tag="VVR43_001703"
     CDS             7878..8654
                     /locus_tag="VVR43_001703"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU6150029.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(8626..8727)
                     /locus_tag="VVR43_001704"
                     /pseudo
     CDS             complement(8626..8727)
                     /locus_tag="VVR43_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            8956..9687
                     /locus_tag="VVR43_001705"
     CDS             8956..9687
                     /locus_tag="VVR43_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150030.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            9702..10853
                     /locus_tag="VVR43_001706"
     CDS             9702..10853
                     /locus_tag="VVR43_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU6150031.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFIIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(10905..11564)
                     /locus_tag="VVR43_001707"
     CDS             complement(10905..11564)
                     /locus_tag="VVR43_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU6150032.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            11634..12080
                     /locus_tag="VVR43_001708"
     CDS             11634..12080
                     /locus_tag="VVR43_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6150033.1"
                     /translation="MTIRFEEKVSIENAQLVCQWSNSLGKVFQEQWMGPRIPFPLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            12225..12497
                     /locus_tag="VVR43_001709"
                     /pseudo
     CDS             12225..12497
                     /locus_tag="VVR43_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12607..12810)
                     /locus_tag="VVR43_001710"
     CDS             complement(12607..12810)
                     /locus_tag="VVR43_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU6150034.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(12841..13449)
                     /locus_tag="VVR43_001711"
     CDS             complement(12841..13449)
                     /locus_tag="VVR43_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU6150035.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(13488..13658)
                     /locus_tag="VVR43_001712"
     CDS             complement(13488..13658)
                     /locus_tag="VVR43_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU6150036.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(13670..14236)
                     /gene="amaP"
                     /locus_tag="VVR43_001713"
     CDS             complement(13670..14236)
                     /gene="amaP"
                     /locus_tag="VVR43_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU6150037.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(14320..14484)
                     /locus_tag="VVR43_001714"
     CDS             complement(14320..14484)
                     /locus_tag="VVR43_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU6150038.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
BASE COUNT         4599 a         2597 c         3154 g         4239 t
ORIGIN      
        1 tactaaattc tcttgttaaa aaaaattaaa tattgtatag taatattaga atgttcgtaa
       61 tggaggactg aaatgaaaaa tataaatggg aaaaaggtaa ctatttatga tattgcacgt
      121 ttatcaggtt tttctccaaa aacagtttca cgagttatta atggtggagt aaatgttaaa
      181 gaagaaactt atcaagcgat tcaaaaagtt atagaggaat tgtcgtatat tccaaatgcg
      241 tatgcaaaaa atttaactaa aaaagaagct ataaatatat tgatttctgt aaaaaaaatc
      301 gactcttttc ctttaatttg gtttcatacg ctgttagata aagtgttacg gacgtgtaaa
      361 gaatttggtg ttaatgctat agttgagtac tttggagagg aggatacaat tagtaattca
      421 attatatcaa gcacaggtag cctagtagat ggtgttattg ttttttatga aagtgtagat
      481 gatatcagaa ttcagtattt aaagaagaac catatgcctt ttcttgtttt cggtgaatct
      541 caaacgtctg gagtagtcta tgtatctaat aataattttc aagctactta tgatatgatg
      601 aaagctgtaa ctgaagaaaa atttaaaaat atgtggttgc ttatgggagg agaatcccat
      661 gttaataagg atcgtgaaag aggtgtgcgt tcttttctga atgataaaaa ttactttatg
      721 gatttaaaag tcatttatgg cttatctaca attgattcag tttattctta tgcaatgcag
      781 cacttgacta cccaaaatta tccggacatt atttttgttt caggagatga aaaggttcag
      841 ggcttgattc gtgcgtgcta tgagaaagga attcttattc cagatgatat ttctatcatt
      901 ggatttgata atattcctat ttctcagtat tatactccag ctttgtctac aattgctccc
      961 aattatgtta aattggctaa agaaatgata gaaggtgttt tagcaattat taaaggggaa
     1021 agtgtcacat ctgttgaagt ttctcctaaa tttgttagga gacagagttt ctagtattgt
     1081 ttaattcttg aaaatcctag tggaaaagat ggagtgttct aaaataagtt ctgtttagcc
     1141 tccattcagt ttctattgag ttggatccaa tttctaacaa gtgggacatg ttcatgttcg
     1201 atctaaggaa gacatggtca cattcgaatg atattttcaa aaaaatcgta aaaaagtctt
     1261 gacaaagaaa aaacaaagta ttaaaataag ttcaacaaat cagaaaagta actatttttg
     1321 atcttcaggg agcctgtggt gattgtgaat aggtggttgg aagtagtgaa agtgggctga
     1381 ttttgaaaat gaatttgaaa caatgaaaat tcggtgcgca caccttacag tgcagcttgt
     1441 tgttaaacaa ggcagagatg taaagggata gtccctttat aattgaggtg gcaccgcgtt
     1501 accaacgccc tcacacggaa gtatattctg tgtgtgggct tttttctatc cgtcgtttgg
     1561 tttatctttt attagggcct taagtcgctt tgatgaactt gagttctatc tacagctcct
     1621 tgcctactac taaaagcaaa caaaaaggct ggactaatac gaaaaaagct agtgatactc
     1681 aatgaaaatc aaagaacaaa ctaggaaact agccgcaggt tgctcaaaac actgttttga
     1741 ggttgtggat agaactgacg aagtcagctc aaaatactgt tttgaggttg tggatagaac
     1801 tgacgaagtc agctcaaaac actgttttga ggttgtggat agaactgacg aagtcagctc
     1861 aaaacactgt tttgaggttg tggatagaac tgacgaagtc agctcaaaac actgttttga
     1921 ggttgcagat agaactgacg aagtcagtaa ccatatctac ggcaaggcga cgttgacgcg
     1981 gtttgaagag tttttcgaag agtataaagg tgtaccgaga tgaacatctc ttcatcaatg
     2041 tctctggtcg tggaggcaag gacctagctg cgattgcaga ctactagaag ctaaaaaata
     2101 atagatggaa aaattacagt tctttctctc acagagagct tgtggttgct gaaaacaagc
     2161 agagaaagct gtaaagttgg gttcatctga aacgagagaa gaaaacatca ttctcaaggg
     2221 agtgcccttt atcgcacagc ctgttacagg agatatctga gacaggaatg agagatagga
     2281 gaaatcctat aattgaggtg gcaccgcgaa tttcgtcctc acgcaagtta ttttgcgtgg
     2341 ggatttttca tacagtcgct acgaactaga attagaactg aaaggaaaat tacaatggaa
     2401 cgaatcattc atggagatgt cttatcacca atcttggctt atatgcgctt aaaggggcaa
     2461 cacaaggtta tcttagagag tattccgaga gacaaggaaa cagctcgttt ttctatccta
     2521 gcctataatc caatttttga gattaagttt gaaaatggag ttctctatca aaatggtcaa
     2581 gtgattgatc gggatccctt ggatttcctt tatgaagtga ttcataagag tcagcaccac
     2641 tcagagctac cttttggtgg tggagccgtt ggttttgtgg gttacgatat gatttcactt
     2701 tatgaagaaa ttggtcaaat ccctgaggat acaattggga cgccagacat gcatttcttt
     2761 gtctatgaga gctatatggt ctttgaccac aagaaggaga agatacatgt catagaggat
     2821 gcactttata gtgagcgcag tcaagaggcc ttggaaaaat ccttgaacca agtgcttgag
     2881 gaattacgca ttcctgctcc aaatgaattt gaagacttgg atctatctcc gttagacttc
     2941 aaacctcata tcgctcctca gaagtttgag gaaatggtgg aaacagctcg tgacttgatt
     3001 cgtaatggtg atatgttcca atgcgtactc agccagcgct tttcagcaga ggttactgga
     3061 aatccatttg acttctacag aaatctccgc gtgaccaatc catctaatta cctttatttc
     3121 tatgactttg gggattatca aatcatcggt gccagtccag aaagtttggt ttctgtcaaa
     3181 aatggcatcg tgacaaccaa tccgattgca gggacgcgac caagaggggc tacggatgaa
     3241 gaagacaaga ccttggcgac tgacctcctc tctgatgaga aggaaacagc agaacatcga
     3301 atgttggtag acttggggcg taacgatatt ggccgcatct ctgaaacggc cagtgtccaa
     3361 gttactaagt atatggaggt ggagctcttc cgctacgtca tgcatttgac cagtgtggtc
     3421 aagggacgtt tgcttgcaga actcactgcc atggatgcct tgaaagcaac gcttcctgct
     3481 ggaaccgttt ctggagcacc aaagattcgg gcgatgagac gcatctatga actggaaacg
     3541 gaaaaacggg gcgtatatgc aggagcaatc ggctacttgt ctgcgacggg tgatatggat
     3601 ttggccatcg ccatccgaac catgattctc aaaaatcaaa gagcctatgt gcaggctggg
     3661 gcagggattg tctacgactc tatcgcccaa aacgaatacc aagaaaccat taacaaagca
     3721 aaatctatga ctagaattgg agaactaaga ccatgatttt attgattgac aactatgatt
     3781 cttttaccta taacttggcc caatacattg ggaattttgc agaagttcag gttctgagaa
     3841 atgatgattc caagctgtat gaagaagctg aaaaagcaga tggtctggtc ttttctcctg
     3901 gtcctggttg gccagttgat gctggaaaga tggaagacat gatttgtgat tttgcaggca
     3961 agaagccgat tctagggatt tgtttgggtc accaagccat tgcagaagtc tttggtggta
     4021 agctaggttt ggctccaaaa gtcatgcatg ggaaacagag caatatcaac tttgaagcgc
     4081 catctgtttt gtatcaaggt attgaggatg gccgtgcggt catgcgttat cacagtattt
     4141 tgattgagga aatgccagaa gactttgaag tgacagctcg ttcgactgat gaccaagcca
     4201 tcatggggat tcaacataaa aacctaccaa tttatggctt ccagtaccat ccagagagca
     4261 ttggaacgcc agacggcttg tcttctattc ggaattttat cgaggaggtt gtaaagtgag
     4321 gaaactagga tgaaagagat tattgaaaaa ctagcaaaat ttgaaaattt atcaggtgtg
     4381 gaaatgacgg atgtcattga gcgtatcgta actgggcgtg taactgaagc gcagattgct
     4441 tctctcctct tagctcttaa gatgaagggg gaaacacctg aagaacgtac agccattgcc
     4501 caagtcatga gaggacatgc ccagcatatt ccaactgaga ttcatgatgc tatggacaac
     4561 tgtggtacag gtggggacaa gtctttcagt tttaatattt ccacaactgc agcctttgtc
     4621 ttggctggtg gcggtattca catggccaag catggtaacc gctcgatttc ttctaaatct
     4681 ggttccgcag atgtcctcga agccttggga atcaatcttg acctcaaacc agctgaacta
     4741 ggtaaggtct ttgataaaac tggaatcgtc tttctcttcg ctaaaaatat gcacccagct
     4801 atgaaataca tcatgccagc tcgtttggaa ttgggaattc caacgattat gaacttgact
     4861 ggtccactga ttcatccaat ggctttagaa acacagcttc ttggaattag tcgtccagaa
     4921 ctcctagaaa gtacagctca ggttttgaaa aatatgggtc gcaaacgtgc catcgtggtt
     4981 gctggaccag aagggttgga tgaagctggc ttgaacggaa caaccaagat tgcacttctt
     5041 gaaaatggcg aaatcagctt gtcaagcttt actccagagg atttgggaat ggaagactat
     5101 gctatggaag atattcgtgg tgggaatgct caggaaaatg cagaaatttt gcttagcgtt
     5161 ctgaaaaacg aagcaagtcc attcttggaa acgacagtct tgaatgctgg tcttggtttc
     5221 tatgctaatg gtaagattga tagcatcaag gaaggagttg ccttggcccg tcaagtgatt
     5281 gctagaggca aggcccttga aaaactcaga ctgttacagg agtaccaaaa atgagtcagg
     5341 aatttttagc acgaatctta gagcagaagg cgcgtgaggt ggagcagatg aagctggagc
     5401 aaatccagcc tctgcgccag acctatcgct tggcagaatt tttgaagaat catcaggact
     5461 gcttgcaggt aatcgctgag gtcaagaaag ctagccctag tttgggagat atcaatctcg
     5521 atgtggatat tgtgcaacag gcccagactt atgaagaaaa cggagcagtg atgatttcgg
     5581 tgttgacaga tgaggttttc tttaaagggc atttggatta tctacgggaa atttccagtc
     5641 aggtagagat tccgacgctc aacaaagact ttatcataga tgaaaagcaa atcatccgcg
     5701 ctcgcaatgc aggtgcgaca gttatcttgc ttattgtggc agccttgtcc gaagaacgcc
     5761 tcaaggaact gtatgactac gcgacagagc ttggtctgga agtcttagtg gagactcaca
     5821 atctagctga actagaggta gcccacagac ttggtgctga gattatcggg gtcaacaacc
     5881 gcaacttgac tacctttgag gtcgacttgc agaccagtgt agatttagcc ccttactttg
     5941 aggaaggtcg ctattacatt tctgaatctg ccattttcac agggcaggat gcggaacgac
     6001 tagccccata ctttaacgga attttggtag ggacagctct tatgcaggca gaaaatgtgg
     6061 cccagagaat caaggagttg cagattgaca aaggttaaaa tttgtggact atcgaccaaa
     6121 gaagcggtgg aaacagccgt ttcagcagga gccgactata tcggttttgt ctttgcacct
     6181 agtaaaagac aggtgacttt agaagaggca gctgagttgg caaagcttat tcctgcagat
     6241 gtgaaaaagg ttggagtatt tgtttcacca agtcgggtag aactgctgga agcgattgac
     6301 aaagttggct tggacttggt tcaagttcac ggtcaggtgg cagctgattt atttgagaat
     6361 ttgccttgtg ccagtattca ggctgtgcag gtagatggaa atgggcatgt ccccaattct
     6421 caggcagatt atctactctt tgatgcccct gtggcaggaa gtggtcagtc ctttgattgg
     6481 ggtcaactgg atacgactga actagcacag cccttcttta tcgcaggtgg ccttaatgaa
     6541 gataatgtag taaaagcaat tcaacatttt actccctatg cagtagatgt atcgagcgga
     6601 gtagagacag atggacaaaa agatcatgaa aagattagaa gatttataga gagggtaaag
     6661 catggcatat caggaaccaa ataaagatgg attttacgga aaattcggcg gacgttttgt
     6721 cccagaaaca ttgatgacag cagttttgga gttggagaag gcctaccgtg aaagtcaggc
     6781 agacccaagt ttccaagagg aattaaacca gcttttgcgc cagtacgtag gacgtgaaac
     6841 tcctctttat tacgcaaaaa acttgaccca gcatatcggc ggagccaaga tttatctcaa
     6901 acgggaagac cttaaccata caggagccca caagattaac aatgccttgg gacaagtttg
     6961 gcttgccaaa cgcatgggta aaaagaaaat tatcgcagaa actggtgctg gtcagcacgg
     7021 tgtggcaact gcaactgctg cggccctctt taacatggaa tgtaccatct acatgggtga
     7081 ggaagatgtc aaacgccaag ccctcaatgt cttccgtatg gagcttttgg gagctaaggt
     7141 cgaggccgtg acagatggtt cgcgcgtgct caaggatgcg gtcaatgcag cccttcgttc
     7201 atgggtggct aatatagatg atacccacta tatccttggt tctgccttgg ggcctcatcc
     7261 atttccagaa attgttcgtg acttccaaag tgtcattggt cgagaggcta aacaacagta
     7321 ccgtgacttg acaggacaaa atctgccaga tgccctagta gcctgtgttg gtggtgggtc
     7381 gaatgccatc ggtctcttcc atccctttgt agaagatgag tcagtagcca tgtatggagc
     7441 tgaagcggct ggatttggtg tggatacgga gcaccacgca gctaccttga ccaagggtcg
     7501 tccaggtgtc cttcacggtt ccctcatgga tgtgctccaa gatgcccatg gtcaaattct
     7561 tgaagccttc tctatctcag caggtttgga ctatcctggt atcggtccag agcattctca
     7621 ctaccacgat attaaacgtg ccagctatgt ccctgtgaca gacgaagaag ccttggaagg
     7681 attccaactc ttgtctcgtg tggaagggat tatcccagct ttggaatcta gccatgctat
     7741 cgcctttgcg gtgaaattgg ccaaagaact tggaccagaa aagtctatga ttgtatgcct
     7801 atcaggtcgt ggggacaagg atgtggttca agtaaaagac cgcttggaag cagatgcagc
     7861 aaagaaggga gaagctcatg cctaagacac taacaaaaaa attaaatgct attaaagcag
     7921 ctggaaaagg aatttttgtt ccctatatca tggctggtga ccacgaaaaa ggtttggatg
     7981 gtcttgctga aacaattcac tttttagaag atttgggtgt ctctgcaatt gaagtgggta
     8041 ttcccttttc agaccctgtt gcagatggac ctgttatcga agaagctggc ttgcgcagtt
     8101 tagcccacgg gacctctacc caggctttag ttgaaacctt gaaaaccatt gaaacagaga
     8161 ttccactggt catcatgacc tacttcaacc ccctctttca gtacggtgtg gagaactttg
     8221 tcaaagatct ggctgataca gctgtgaagg gcttgattat cccagacctg cctcatgaac
     8281 atgccaactt tgtagaacca tttttggcag atacagatat cgccttgatt cctttagtaa
     8341 gcttgaccac aggaattgag cgccagaaag agttgattga aggggcggag ggattcgtct
     8401 atgccgttgc catcaatggg gtaacaggga aatcaggcaa ttaccgtgca gatttggaca
     8461 agcacttggc gcaacttcat caagtggccg acatcccagt cttgacaggt tttggtgtat
     8521 ctagtcaagc cgatctggaa cgcttcaatg cggtgtcaga tggtgttatc gtcggttcga
     8581 aaatagtaaa agctctccac caaggagagc cgattcagga ctttatcaaa caagcagtag
     8641 cttaccaaaa ataattaaac aagtagcaag taagaggaaa ggcacgaaag gaagtctttc
     8701 ctttttcttt tgcaggagaa aggctagttt tatagtgaat tgaatctgga atattacact
     8761 acggttccta aaatattttc agaaagtgat ttgaatttcc caataaattt gttcagtttt
     8821 taattgattt tactatagaa gatataattt tctaaattac tctgacacag aactttaaga
     8881 aaaagctaat tattgtagta atttctttaa gaaaatgata taattcatta aaaagtattt
     8941 ggaggaggaa gaattatgtt gaatcaggat ctctttgatt cgcttgaggc acaaaaaatt
     9001 gtagatactt tgatgaaagg gcaaaaagat tatgtagatg aacgtctaga aaaaagagag
     9061 acaatgatag tgtcgaatgg ttatgcatgg acgcgaccta atcatattga tactgcattt
     9121 gcatcagcag atttgtttga gtataaatta caattagcag gacagacttg gggatattta
     9181 gaatttgaaa caaatacaga aaaatatggg aaagtattgt taattataaa gggtaagaag
     9241 cgacttacga accaatttcc tttggtacaa aaaaataaga gtggctactt atttgaatac
     9301 gctcagatga atacacttta tcttaatcaa cattcttcct acaaaaatga tgaagatagt
     9361 cattcctttc caattcagat ggagttagtt tctgatgaaa tgattcaaga aattgaacaa
     9421 gctactaaaa attcgaatat cgaaaaattt atgattttaa cttatgaggc ggactcagaa
     9481 aacaatatta tatctgtaga tgttgttatg cctgatgcac gaactggtca gttacacttg
     9541 attcaagatt tgtctgagta tattcaatca agttcgtacc atttcgaaga agctaaatat
     9601 caagatattc ctaatttttc agaattatcg gaaacagaag attttgaaat tattccaaga
     9661 atagaaaaac aagaaggtca aaagtagtaa ggagtatgta aatgtttaat ggtcgggtat
     9721 tgaaagaatt acggctgtta aatggtttaa gtagagcaga attagctcag agaattaatt
     9781 taacggaaca agccatttgg cagtttgagt ccaacgaaac gaaacctaaa ttatcaacca
     9841 aaatgcattt ggccaaccaa tttcatgttg atttaactta ttttgaacag gaagaagaga
     9901 gcattcgatt tgattcttct gtaattgcct ttagaaatgc agacctagca acacggaaaa
     9961 caatagatat tcaaactatg tatttacata aggtagatag tttgattgat tattttgaaa
    10021 gttttataat tatacctaat attataattc atgacctaag taatgtagtg agtgaatctt
    10081 atcataaggg agaatccatt gaggaattgg ctctttatgc cagggaaaaa ttaggtattt
    10141 caaaagataa tcatgatttg ctttataaat tagaacgttc aggcatctat atcgtggaac
    10201 gattaattaa tggccaagct gatgcttata gcgcatggtc aaaattggga agaccttata
    10261 ttgtgttggg aacgaataaa tcatctgtac gtcgaaattt tgacttagct catgagctag
    10321 gacatattct tttacataaa tataaagata tgaatgaaga tggcgatcgt ttggagcaag
    10381 aagcaaatta ttttgcatca tgttttttat tgccaaaaga agagttttta gtcaaatttg
    10441 aagagagggt tggcaagcgt gtcagcaatc ctgatagtta tattttattg aagtcggatt
    10501 tgaatgtttc gatacaggct ttagagtatc gagcttttaa gttaggatta ttgactccaa
    10561 agcaacattc ttacttttat cgtcaaattg cgcaaaaagg ttacaaaatg attgaacctt
    10621 tggatgatca aatttttgtt aaaaaaccaa gcaaagtaaa gagtattctg gacgtcgttt
    10681 tgagtaatca tctagtcagt ctagcgacta taatgtctaa acaaagtatt cgtttacagt
    10741 ttataagcga aatattttca gtcgaaatga aattttttga tcagtatcaa gaagatagaa
    10801 gaacagatcg atttgataac atcatccctt tgtacaaaag aaataattta taatttaact
    10861 gtgaaataat ttcatgaagg acatatggca gaaattggac tttatcaaac aagcagtagc
    10921 ttaccaaaaa taatcaaaca agtagcaagt aagaggaaag gcacgaaagg aagtctttcc
    10981 tttttctttt gcaggataaa ggccaggata cccgtcgcag aagcaaactg aatcaagatc
    11041 agtaactccg ttacgctaaa gacgagagca caagaagcta aaaagaggaa atctcctgcg
    11101 cccatgcgga tatcgataaa atgagccaaa attccaagag caaggaagga gaccatgacc
    11161 agattccagc cagaggaagc tattaggatt aggtggaaag tcatccagac cagtaaggga
    11221 tattcctgat ggtgaaagtc gtagataccc aaggtcaaac cagcggtgat taggacgact
    11281 tgccccaagg aaagcaattc ccaagagtaa agcagaaaga ggagtcctaa gactaattca
    11341 aagagggcat accagacagg atagcgaact ttgcagtagc gacagcgaaa gcgattgaag
    11401 acctgtgaga gaatcggaat caaatctaag ggacgcaagc gagtctgaca ggaatcgcag
    11461 tgactggctg aactgataat ggattgctct ggaaaacggt caatgaccaa accaagaaag
    11521 gaagcgagaa tgctcccgac gagaaaaaaa taaaaatcaa tcatacttat ctattcgtaa
    11581 aaaatgggag aaatagtata atggagaaac atagataaga tggtgaggaa aagatgacaa
    11641 ttcgttttga agaaaaggtg agtatagaaa acgctcagct cgtatgccaa tggtccaact
    11701 ccttaggcaa agtctttcaa gaacaatgga tgggaccaag gattcctttt ccactgaccc
    11761 ttcaagcctt ggaaggagtc ttttcaatct ttgatgaaca agagtttgtg ggacttatcc
    11821 agaaaatcag gctagaagac agcaatcttc atatcgggag attttttatc aacccccaga
    11881 aacaggagca agacttaggt agccaggctt taaggaaatt tgttagtttg gcctttgaaa
    11941 atgaagatat agatagtatt tctctaaatg tcttcgaggc aaatcaaaga gctcagaatc
    12001 tttaccaaaa agaaggattt gaaattgttc aaatggttga agcacctgta cgaaaatata
    12061 gtagattgaa actagaatag tacacctctg cttctaaaac attgttagaa atcgatttga
    12121 ctgtcccgat cgattcgtcc tgttattatt tcattttact atacattatg aaaaagggga
    12181 gatagaaagc aaacagcctt gaaatcaatg ttgactgcga ttatgaacct gaatcagccc
    12241 ctcaaaaggg actgtatatg aatgaacgtt accagtgttt aaaaactaaa gaatatcagg
    12301 cacttttatc ttccaagggt agacaaattt tcgctaaacg taagattgat atgaaatctg
    12361 tctttgggca gataaaggtt tgtttgggtt ataagagatg tcatctgaga ggtaagcgtc
    12421 aagtgagaat tgacatggga ttcatactca tggccaacaa cctgctgaaa tataataaga
    12481 gaaagaggca aaattaaaaa gctagagttc cgcaattggg aatctctagc tttttgtttt
    12541 ctgagaatca tcttgactca gactcttttg actaatgtta ccaaaaagat aaagtaactt
    12601 ttaaccttat ttatcgtcgc cactcaacat gtttttaaca ccttctacag caccttctac
    12661 agcgtcttta gcgtcttcgg caacttcttt tactttagaa acaacttttt cagctgctcc
    12721 ttctttttcc attttttcat caccgatggc tttcccaaca ccttctttaa tagaaccttt
    12781 agcttgattt aatttttctt ctactgacat gataatttct cctgttatat ttattttatc
    12841 ttagtttaca cgagtgtttt cgtgagatac tacaccattt gctgcacctt taacagcttc
    12901 tacaccttcg ctaacttttt cttgaacagt tgagaaacca gatccaagac cagatttagc
    12961 tttttcgaat tgttctgaag tgaattctcc tgttgattca gcaacgtcag atacgcgatc
    13021 ttgaaggctt actgagtctg cttcatgctg ttctttagtt ttgatgtcga caacgtttac
    13081 gttgatttca acaatttcca agtcagtcat tttagcaact tctgaagata cgatttctct
    13141 gatttctgaa tataaagctg gaacattttt ttggtactca acaataacgt ttaagtcaac
    13201 tgcaacttgt gttttaccaa cttctacgtt aacaccactt gttacgtcat cgctgttaac
    13261 gattttttct ttaagatttg agaagaaacc accatcgatt cccaaaagac ctgaaacgtt
    13321 ttctagtgaa agaccaatga ttttttggat aactttatct tcgtaagtaa gttccccttt
    13381 gatttcgtga gctacaacag tagcatcttt cttttctacg ttagtgtttg tgtttttttc
    13441 gtttgacata tgaaactcct ttaattaaat tagtaatttt tattttttta tttatctata
    13501 tagttttttt cgatatataa tccagctgca actcccagtg ctcctaaaat caatacaaat
    13561 attgttttga agaagccaaa ggagacaatc aaacaagcca gaaatacgcc tatgagacca
    13621 gcgataattg gatatcgata ttgtttaagc cattccattt tttacttcct tacttcacac
    13681 gactaacagt ctttttgttt tgaggttttg gttggtaatt ttttactgca acttcaagtt
    13741 ttacttgacg ctcaatacca aaaaactgct tcaatccatt agttatttca ttttgaatta
    13801 tttggcatct gtcagcgatg ttgtctgaag gaagaatttt accttctaca tgaacgaaac
    13861 atttattttt tcgtaaattt acatgaacag ttgggttctt gatcaatcta tgatcactca
    13921 ccaaacttct aacaaaacct tcgattgccg aattctttaa ttttaatgta tcgtttttag
    13981 tttcaagttg gatttccaag taacgtttag gataaaacat cacaactaaa atggataata
    14041 aaactaaagt tgatagaacc actgtccccc aaaagacata tctagcaaga tagaattcaa
    14101 ctacggagtt ctgtctccag ctaagtagat gaatacctag atcactaact tgatgataat
    14161 ctatcaaaac aggaaggaaa attgtcaaga ttaaaataca gaaaataatg aaacatattt
    14221 tctttgcttt tgacatatac aatcctttcg atttaacatt taaactattt ttcccgtcat
    14281 tgatttaaaa atagtttgct aactttactg gcgaaaagtt tactttctac ctgtaaagaa
    14341 tgacactaca gtaatcacaa tcgctgcacc tacaatagat gggagcaaag ccattccagc
    14401 gattgatgga ccccaactac ctaaaagaga ttgtcctgca tatgccccga ctaaaccagc
    14461 gaatacattt gcgatgattc ccatagaact acttttttag tgattttacc tgccaagaga
    14521 ccaataagac ctccagcaat aattgatcac aacactgcct accctccttt tttattttaa
    14581 tatcaaaaa
//
LOCUS       DAVHSY010000044        14273 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.045, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000044 DAVHSY010000000
VERSION     DAVHSY010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14273
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.045"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            81..878
                     /locus_tag="VVR43_001715"
     CDS             81..878
                     /locus_tag="VVR43_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU6150039.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1026..1148
                     /locus_tag="VVR43_001716"
     CDS             1026..1148
                     /locus_tag="VVR43_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine sulfhydrylase"
                     /protein_id="HEU6150040.1"
                     /translation="MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTFFVFDDT"
     gene            1170..2210
                     /locus_tag="VVR43_001717"
     CDS             1170..2210
                     /locus_tag="VVR43_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEU6150041.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILAIAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFFDIDNLEEVEAAIKDNTKLVLIETLG
                     NPLINIPDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSVTKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTRDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKGVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            2381..3655
                     /locus_tag="VVR43_001718"
     CDS             2381..3655
                     /locus_tag="VVR43_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU6150042.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3665..4543
                     /gene="truB"
                     /locus_tag="VVR43_001719"
     CDS             3665..4543
                     /gene="truB"
                     /locus_tag="VVR43_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU6150043.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTKTEDASGEVVAETPVLSLLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4784..5082
                     /locus_tag="VVR43_001720"
                     /pseudo
     CDS             4784..5082
                     /locus_tag="VVR43_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
     gene            5190..5828
                     /gene="udk"
                     /locus_tag="VVR43_001721"
     CDS             5190..5828
                     /gene="udk"
                     /locus_tag="VVR43_001721"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU6150044.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5956..7296
                     /locus_tag="VVR43_001722"
     CDS             5956..7296
                     /locus_tag="VVR43_001722"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU6150045.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGNYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7274..7486
                     /locus_tag="VVR43_001723"
     CDS             7274..7486
                     /locus_tag="VVR43_001723"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU6150046.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7483..8358
                     /locus_tag="VVR43_001724"
     CDS             7483..8358
                     /locus_tag="VVR43_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU6150047.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8351..9166
                     /locus_tag="VVR43_001725"
     CDS             8351..9166
                     /locus_tag="VVR43_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU6150048.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9159..9590
                     /locus_tag="VVR43_001726"
     CDS             9159..9590
                     /locus_tag="VVR43_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU6150049.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9597..11264
                     /gene="recN"
                     /locus_tag="VVR43_001727"
     CDS             9597..11264
                     /gene="recN"
                     /locus_tag="VVR43_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU6150050.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11266..11994
                     /locus_tag="VVR43_001728"
     CDS             11266..11994
                     /locus_tag="VVR43_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU6150051.1"
                     /translation="MTDYYVIGDVHGKAEMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12073..13896
                     /gene="lepA"
                     /locus_tag="VVR43_001729"
     CDS             12073..13896
                     /gene="lepA"
                     /locus_tag="VVR43_001729"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU6150052.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14055..14135)
                     /locus_tag="VVR43_001730"
                     /pseudo
     CDS             complement(14055..14135)
                     /locus_tag="VVR43_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT         4235 a         2590 c         3388 g         4060 t
ORIGIN      
        1 ttttatgaaa tacagaaaac gcttcctaaa acctaaagtt tgtgatataa ttatcaagaa
       61 aaaagattta ggagtttatt atggtttctt cggaatttat ctcaaagatt gaatttgctt
      121 gcaataagaa agaaagtctt tatagtcaaa gcaaatttaa gtatgcgatt cgttcgatgt
      181 tcgcaggtgc atttttaacc ttcagtactg ctgcaggtgc agttggggct gacttgatta
      241 ataaaattgc accaggtagt ggacgcttcc tctttccatt cgtttttgct tggggcttgg
      301 cctacattgt ttttttgaat gccgagttgg tcacttcaaa catgatgttc ttgactgctg
      361 gtagtttctt aaaaaaaatc tcttggagaa aaacagctga gattttacta tactgtacct
      421 tgttcaacct tatcggagcc ttgatagcag ggtggggctt tgctcattcg gcagcctatg
      481 cgaatctgac acacgatagt ttcatctcag gtgttgttga gatgaagtta ggccgctcaa
      541 atgaattggt cttgcttgag gcgattttgg caaatatttt tgtaaatatt gcgattctgt
      601 catttatttt ggtcaaagat ggtggtgcca aactttggct tgtgttgtca gctatttaca
      661 tgtttgtatt cttaacaaac gagcacattg cggcgaactt tgcttctttc gcgattgtga
      721 aattcagtgt tgctgcggat tcaattgcca acttcggtgt tggaaatatg cttcgccact
      781 ggggtgtgac tttcatcgga aactttatcg gaggaggcct cttgatgggt cttccatatg
      841 ccttcctcaa taaaaacgaa gatacttatg tagattaaga aaatgagcac gattgagtcg
      901 tgcttttttc attttcaaaa taaggtaata gctatttctt atatcaaaat atagaaaact
      961 gatatttgta aactataact caaggtgcta caatatcctt aataaaataa tatggaggtc
     1021 accttatgac ttgtgatttt aaatttgaaa ctctacaact acatgctggt caagttgtgg
     1081 ctccagctac taagtctcgt gcagtgccga tttatcaaac aacatttttt gtttttgatg
     1141 acacgtagga aggtgccgat ctgtttgcct tgaggaaacc agggaacatt tatactcgta
     1201 tcaccaatcc tacaacagct gcccttgaag gtggtgttga agcgctagca acagcatcag
     1261 gtatgactgc agtgacttat actattttgg cgattgccca tgctggtgac catgtagtgg
     1321 ctgcttcgac tatttacggt ggaaccttca atcttttgaa agaacccctt cctcgttatg
     1381 gtatcacaac aacctttttc gatattgata atttggagga agtagaagca gctatcaaag
     1441 acaataccaa gcttgtcttg attgaaacct tgggtaaccc cttgattaat attccagacc
     1501 tggaaaaact ggcagagatt gctcataaac atcaaatccc acttgtgtca gacaatactt
     1561 ttgcaacacc ttatttgatt aacgtcttct ctcatggcgt tgacattgcc attcactctg
     1621 tgactaagtt tatcggtggg catggtacaa ctattggagg aataattgtc gatagtggtc
     1681 gttttgactg gacggcttca gggaaattcc ctcaatttgt tgacgagggt ccaagctgcc
     1741 acaatttgag ctatactcgt gatgtgggtg cagcagcctt tattatagct gttcgagttc
     1801 aattgcttcg tgatacaggt gcagccttgt caccattcaa tgctttcctc ttgctacaaa
     1861 gacttgaaac ctcttcactt cgtgtggaac gccatgtaca aaatgctgag acaattgttg
     1921 attttcttgt caaccatcct aaggtagaaa aggtaaatta tccaaaactt gcagatagtc
     1981 cttatcatgc cttggctgag aaatacttgc caaaaggtgt cggttcaatc tttaccttcc
     2041 acgtcaaagg tggcgaggaa gaagcacgca aggtcattga taatttagaa atcttttctg
     2101 accttgcaaa cgcggcagat gctaaatcgc ttgttgtcca tccagcaaca accactcacg
     2161 gtcaattgtc agaaaaagac ctagaagcag caggtgtcac accaaactaa attcgtttgt
     2221 caatcggtct tgaaaatgta gaagatttga ttgaagactt gcgcttggcc ttggaaaaaa
     2281 tttaaagtaa aagaagataa acagtgggct tcgactcact gtttttgatt ttccctcagg
     2341 catgatataa tggttaaaga agtctagaaa gaggaacgat atgaacgaaa tcaaatgtcc
     2401 caactgtggg gaagtcttta cagtaaatga gagtcagtat gccgaactct tgtcccaagt
     2461 gagaacggca gagtttgata aggaactaca cgataggatg aagcaggaac tggccttggc
     2521 tgagcaaaag gccatgaatg agcaacagac taaactggct cagaaggatc aagaaattgc
     2581 gcaattacag agtcagatcc aaaactttga tacagaaaaa gaattggcca agaaagaggt
     2641 tgaacagaca agccatgagg ctctcttggc taaggacaag gaagtacagc tcttagaaaa
     2701 tcagttggct accttgcgtt tggagcatga aaatcaacta caaaagaccc tttctgacct
     2761 agaaaaagaa cgggatcagg ttaaaaacca actacttttg caggaaaagg aaaatgaatt
     2821 atctttggct tctgttaagc aaaactacga agcccagctc aaggcagcta gtgaacaagt
     2881 cgagttttat aagaatttta aggctcaaca atctacaaaa gcgattgggg aaagcctaga
     2941 acagtatgca gagagtgagt ttaacaaggt tcgtagtttc gcctttccaa atgcttactt
     3001 tgagaaggat aacaaggtct cttcgcgtgg gtctaaaggg gactttatct tccgtgagtg
     3061 tgatgaaaat ggagttgaaa tcatttctat catgtttgag atgaaaaacg aagcggacgg
     3121 aacagagaag aagcacaaga atgcagattt ttacaaggaa ttggacaagg accgtcggga
     3181 gaagaactgt gagtatgccg ttttggtgac catgcttgag gctgataatg actactttaa
     3241 cacagggatt gttgacgtca gtcacgagta tgaaaaaatg tatgttgttc gtcctcaatt
     3301 ctttatccaa ttgattggtc tcttacgtaa tgcggcgcta aattccctaa aatacaagca
     3361 ggagttggcc ttggttcgcg agcaaaatat tgacattacg cattttgagg aagatttgga
     3421 tgcctttaag ctagcttttg ctaagaacta taattcagct tcgactaact ttggaaaagc
     3481 tattgatgaa atcgacaagg ccatcaaacg catggaagag gttaagaaat tcctgaccac
     3541 atctgaaaac caactccgtt tagctaacaa caaattggaa gatgtctctg ttaaaaaatt
     3601 gacccggaaa aatccaacaa tgaaagcgaa gttcgaagca ctgaaggggg agtagaaagc
     3661 aaaaatgaac ggtattatta acttaaaaaa ggaagcagga atgacctcgc atgatgcggt
     3721 ttttaaactg cgtaagattt tgggaaccaa gaaaattggt catggtggaa ccttggatcc
     3781 ggatgtggtg ggtgttttgc cgattgcggt tggcaaggcg acacgcatgg tcgagtttat
     3841 gcaggacgag ggtaagatct atgaggggga aatcactctg ggctattcca cgaagactga
     3901 ggatgctagt ggggaagtgg tcgcagaaac ccctgttttg tctctcttgg atgaaaagct
     3961 tgttgatgaa gcgattgcta gcttgactgg gcctattact cagattcccc ctatgtattc
     4021 ggcagttaag gttaatggtc gcaagctcta tgagtatgcg cgtgctggtc aggaagtgga
     4081 gcgtccagaa cgtcaggtga ccatttatca atttgagcga acaagtccga tttcttatga
     4141 tggccaactt gcccgattca cttttcgtgt aaaatgcagt aaagggacgt acatccgtac
     4201 tttgtcagtt gatttgggtg aaaagcttgg ttatgcggct catatgtccc atttgactcg
     4261 tactagtgct gctggcttac aattagaaga cgctcttgcc ttggaggaaa ttgctgaaaa
     4321 agtagaggct gggcaattag attttctcca tcctttagag attgggacag gtgaccttgt
     4381 caaagttttc ctaactccag aagaggctac agaagttcgc tttggtcgtt ttattgagct
     4441 agaccaaacg gacaaagaac tggctgcctt tgaagatgat aaattgttag ccattctaga
     4501 aaaacggggc aatctctata agccaaggaa ggtttttagc tagatcgttt aggaataaaa
     4561 atcgggtgat agataacaat tgcttgataa aaccccatac taatagtaga atggttttgg
     4621 gaattataat attccaattg ttgcgagttg taggtactca aataatctat atagaaattt
     4681 agaggtgtga aatgaagcaa tttaaaattc tttcagataa atatttagag tccattacag
     4741 gttctgatgg gaacttaggc ccaggatttg gtgtgataat tccatgatgc gaaatgagtt
     4801 tcgagaaagg gtggagcaac ttcttcaaca aaaagaaata aatgaaaata gtgagttgag
     4861 tcacctgttt cgtcttgcta tacaaaattt agacagaaat gaaaaatacc aatcggtcat
     4921 ggccaatttg agtcaagggt tgtcacttta cctcatgacg catcattacc aggcacctaa
     4981 gtctgtcatt gattttggtt tatggattaa gctcctagcc aggaaagagg gagactggct
     5041 ttcttgcaga tgcttgctca aaccctacag ggctttcgtt aaaactgtcg aacatcagag
     5101 ggaagactct ggtgtttttt gctgatgaga ctataaattt tgtaaaaaat gtgatagaat
     5161 agacgacgga taaaataacg gaggatagca tgcaaaatag accaatcatt attggagtga
     5221 caggtggttc tggtggtggt aaaaccagtg tttcaagagc cattttatcg cattttcctg
     5281 atgaaaagat ttccatgatt gagcatgatt catactacaa ggatcagtct catttgacct
     5341 ttgaagagcg tgtcaaaacc aactatgacc atccttttgc ctttgataca gacttgatga
     5401 tcgagcagat taaggaattg ttggcagggc gtccggtgga catcccgacc tacgactata
     5461 cagagcatac acggagtagc aagacctatc gtcaggaacc tcaagatgtc tttatcgttg
     5521 agggtatttt ggtcttggag gacaagcgtc tgcgcgattt gatggatatc aagatttttg
     5581 tggatacgga tgacgatgtg cgcattattc gtcgtatcaa gcgtgatatg gaggagcgtg
     5641 gccgtagcct tgatagcgtt attaaccagt acttaggtgt ggtcaaacca atgtaccacc
     5701 agtttatcga gtcaactaag cgttatgctg atatcgtcat tcctgaaggg gttagcaata
     5761 ccgtggctat cgacctgttg acgaccaaga ttgcaaagat tttggaagaa gctcgaaaca
     5821 gcaaataatc acatgtggag gccttgcctc ctttttctat ttttccctca taatggtaca
     5881 taaatggaga tttttaggca tatttttggt ataataatac ccatgaaaga gcaagtaaat
     5941 gaatagtagg tggagatgga aaagtattta tcggtaacaa ctttgaccaa gtatctgaaa
     6001 atgaaattcg ataaagaccc atacttggaa cgggtctatt taactggtca agtttccaac
     6061 tttcgtaaac gacctactca ccaatatttc tccctaaagg atgaccatgc agttattcaa
     6121 gcgaccatct ggtctgggat ttatcagaaa ttagggtttg acctggaaga aggaatgaag
     6181 atcaatgtga ttgggcgtgt acaggtctat gaaccaagtg gtaactactc catcatcatt
     6241 gaaaaagctg agcctgatgg ggttggggcg cttgcgattc agtttgaaca acttaagaaa
     6301 aaattgacag aagaaggcct gtttcaagaa cgcttcaagc aagctctgcc ccaattttct
     6361 aagagaattg gtgtagtaac cagccgtagt ggagccgtta ttcgagatat tatcacgacc
     6421 gtcagcaggc gattcccagg tgttgacatc cttctttatc cgaccaaggt tcaaggtgaa
     6481 ggggctgcgg aggaaattgc tagaaatatt gcgcgtgcta atcaacggga cgatttggat
     6541 ttgctcatta ttggtcgtgg aggtggttct attgaggatc tctgggcctt taacgaagaa
     6601 attgtggtac gagctatttt tgaatctcgt ttgccagtta tctctagtgt ggggcatgag
     6661 acggatgtga ccttggcaga ttttgtggca gatcgacgcg ctgcaacgcc aacagcggcg
     6721 gctgaactgg caacacctgt gaccaagttg gatgtattag ctcatttgca aaatcaggaa
     6781 aaacggatgg taacggcagt ccgaaatgtt ctatctaaga aacaagaggc tttgaaaaaa
     6841 tgcagtcagt ctgttatctt tagacaacct gagcgcttgt atgacggtta tttgcaacgc
     6901 ttggaccaac tgcaactgcg tttgaaacaa agtttgcgaa ctcggatttc tgataacaaa
     6961 caattagttc aagcaagaac tcatcaatta gtacaattat cacctgttac caaaatccaa
     7021 cgctatcaag accgtttagg acagttggac aagctcttag gtagccaaat ggcgttagtt
     7081 tatgacgcca aggttgctga ggccaagcga ctttcggaag ctttgctcat gttggatact
     7141 agccgaatcg tggcgcgtgg ttatgctatt gtcaaaaaag aagagtccgt tgtagattcg
     7201 gttgagagtt tgaagaaaaa agaccaagta acgcttttga tgcgagatgg tcaagtagaa
     7261 ttagaggtta aagatgtcaa aacaaaagaa atttgaggaa aatctagcag aactggaaac
     7321 cattgtccaa agtttggaaa atggtgaaat tgctctggaa gatgcgatta ctgcctttca
     7381 aaagggcatg gtcttgtcaa aagagctcca agctacgctg gacaaggctg aaaagacctt
     7441 ggtcaaggtc atgcaagaag acggaacaga aagtgatttt gaatgaaaaa gcaagaaaaa
     7501 ttagctcttg tcgagtcggc tttggaagat ttttatggag accagcagtt tgcctctagt
     7561 ttacgggagt ctgttctcta ttctattcat gctggtggca agcgtattcg gccttttctc
     7621 ttgttagaag ttctggaagc cttgcaggtt accatcaaac ctgctcacgc gcaggtagct
     7681 actgccttag agatgattca tacagggagc ttgattcacg atgaccttcc tgctatggat
     7741 gatgacgatt atcgaagagg gcggttaacc aatcacaaga aattcggtga agctatggcc
     7801 attttggctg gagatgcctt attcttagac tcatatgcct tgattgcgca ggcagatttg
     7861 ccaagtcaga ttaaggtgga cttgattgcc aacttatccc ttgcttcagg tagtctgggt
     7921 atggtggcag ggcaagtttt ggatatggag ggcgaacacc agcacttgtc tttggaagaa
     7981 cttcagacta ttcatgccaa taagactggg aagttactag cctatccctt ccaagcggca
     8041 gctattatag ctgaattgtc acctgaaatg caggtgaagc tgaaaactgt gggtgaattg
     8101 attggacttg cttttcaagt cagagatgat gtactggatg tgacagctag ttttgaggaa
     8161 atcggcaaga cacctcaaaa ggatctgcag gcagaaaaat caacctatcc tgccctgttg
     8221 ggcttggaag agtccattgc cttttgtaac caaaccctgg atcaagctaa tgaaaaatta
     8281 gaagaaattg cccagcagct tccctttgaa acagaatcga ttgtaagtgt agtagaaagt
     8341 ttgagaatca atggctaagg aaagagtgga tgtactagct tataaacagg ggttgtttga
     8401 aacgagagag caggccaagc gaggtgtgat ggctggccta gtcgtagcag tccttaatgg
     8461 agaacggttt gacaagccag gagagaaaat tccagatgac accgaattaa aactcaaggg
     8521 ggagaaactc aagtatgtca gccgtggtgg tttgaaactg gaaaaggcct tgcaggtctt
     8581 tgatttgtcg gtggatggcg cgactacgat tgatatcggg gcctctactg gaggttttac
     8641 cgatgtcatg ctacagaata gtgccaagtt ggtctttgca gtcgatgttg gtaccaatca
     8701 gttggcttgg aaattacgcc aagacccacg agttgtcagc atggagcagt tcaatttccg
     8761 ctatgctgaa aagactgatt tcgagcagga gccgagcttt gccagtattg atgtgagttt
     8821 catttccctt agtctgattt tgccagcctt gcaccgtgtc ttggctgatc aaggtcaggt
     8881 ggtagcactt gtcaaacctc agtttgaggc aggacgtgag cagattggga aaaatggaat
     8941 tattcgagat gctaaggttc atcagaatgt ccttgaatct gtaacagcta tggcagtaga
     9001 ggtaggtttt tcagtccttg gcttggactt ttctcccatc caaggtggac atggaaatat
     9061 tgaattttta gcgtatttga aaaaagaaaa gtcagcaagc aatcagattc ttgctgagat
     9121 taaagaagca gtagagaggg cgcatagtca atttaaaaat gaataaaaaa gagagacttg
     9181 aaaaaattag aagattggtg acagattatc aaatcggcac gcaagaagaa attgtagaac
     9241 atttgaaaga agcaggtatc actgccactc aggcgacggt atcccgagat atcaaagagt
     9301 taggtattgt caaaattcct ttgagagaca acacctatgt ctacgaattg ccaaaatcaa
     9361 tcgtaaaaag tctgcaactg gctgaagaca atatcgaatc ggctgaattg atggataaga
     9421 tgatcaatct ccaagttatt ccaggaaata cggcttttgt aaaagctcag ttaatcgaga
     9481 cttttgcaga caagattttt agctgtttga ctgatgatag ctcgatttta gtcattgcca
     9541 gaagtggaag tctagcagag gaaatctttg aacaagtaaa aaattggtag gtctatatgt
     9601 tacttgaaat ttcgataaaa aactttgcca ttattgaggc tatttccctc aattttgaaa
     9661 aggggatgac tgtcctgact ggtgaaacgg gtgcagggaa gtcgattatc attgatgcca
     9721 tgaatatgat gttgggagct cgtgcgacga cagatgttat tcgtcatggt gcaccaaagg
     9781 cagagattga ggggcttttc tcagttgaga atagtcgtct tttacaggaa atttttgatg
     9841 agcaaggttt agaattaggt gatgaaatta tcatccgtcg ggaaatcttg caaaatggtc
     9901 gtagtatcag ccgtgtaaat ggtcagatgg ttaatctgtc tgttttgcga gctattgggc
     9961 aacatcttgt agatattcat ggtcagcatg accatgagga gttaatgcgt ccccaactgc
    10021 atatccagat gttggatgaa tttggtgatg ccgctttttg ggacttgaaa gaaacctatc
    10081 aaacgagttt tgatgcctat cggaaaatgc gcaagcaggt tctggaagtc aagaaaaacc
    10141 aacaggaaca caaggcacgt atcgaaatgt tggaatttca aatggcagag attgaggcag
    10201 caaacttgca ggctggagaa gacttggctc tcaatcaaga gcgagataaa ctcctcaacc
    10261 acaaaaatat tgcggataca ctgaccaatg cctacagtat gttggacaat gaagattttt
    10321 caagtctggc caatgttcgt tcagctatga atgacatgga aagtgtcgaa gagtatgatc
    10381 ctgaataccg tgaaatttca agctctctgt ctgagaccta ctatgtttta gaagacatta
    10441 gcaaacgttt ggaagctatc attgaggacc ttgattttga tggcaatcgc ctgatgcagg
    10501 ttgagaatcg tttggacctc cttcatacta ttactcgtaa gtatggtggg actgttgatg
    10561 atgttttgct ttattttgcc aagattacgg aagaatacaa tctcttgaca ggcaataatc
    10621 tttcgtctga ggacatggaa gcagagctta agaagttgga agtcaatctt gtcaatttgg
    10681 caggtcaact tgcttctgct cgtcataatt tggctcagca actcgaagct gagattaaac
    10741 aagaactgca agatctttat atggaaaaag cccagtttca ggttcgtttt agtaagggaa
    10801 aattcagtcg tgagggaaat aaaatggttg agttttatat ttcaaccaac cctggagaag
    10861 actttaaacc cttggttaag gttgcttctg gaggggaatt atctcgtctc atgttagcca
    10921 ttaagtctgc cttttcacgt aaagaaggca agactagcat tgtctttgat gaggtggata
    10981 cgggagtttc aggtcgtgtt gctcaagcta ttgctcagaa aattcataaa attggtcagc
    11041 atggtcaggt tttggctatc tcccatttgc cacaagtaat tgcgattgca gattatcaat
    11101 tctttattga gaagattagt aatgaccatt caacggtttc gactgttcgt ctcttgacgg
    11161 tcgaagagcg agtggaggaa gttgccaaga tgttggcagg tgatgatgtg acagaagcag
    11221 ccctgacgca agccagagaa ttgttgagaa acagggagaa ataagatgac agattattat
    11281 gtaattggag atgttcacgg aaaagctgag atgctggaag accttctcaa aacctgggat
    11341 ggtcagcccc agttgctctt tctaggtgat ttgattgaca gaggtgagga tagtcaccgt
    11401 gttcttgaaa tggtcaagga cttggtggac aatcaagggg ctatctgttt gtccggaaac
    11461 cacgagtata tgtttttgac ttggctagat gacccagaag aaagttatga ccattatagt
    11521 cgcaatggtg gagatacaac cattaactct atcctaggtc gtcccttgga tgcaccagtt
    11581 gatggagtag aagatgccaa gcgggttgcc gctgaagcgt cagacttggt cgaattcatt
    11641 cgtcaaatgc catttgtagt agagacagac aagtatatat ttgttcacgc aggtattgat
    11701 ttgactttgg acgactggca tgaaacaaca gattataaaa aagtatggct tagaaaacca
    11761 ttccacggag ctgaaaatca tactggaaaa accattgtct tcggtcatac accggtctat
    11821 ggtttgttac agcaagaacg cggtacatct gagctttgga ctacagaaga tggcaagatt
    11881 ggaatggatg gaggagctgt ttatggtggt gtccttcacg ggattgtctt tacagaccaa
    11941 ggaatgacag aacaccactt tatcgaaaat gacggctttg tcgctgaaga ttagtactcc
    12001 tagcagggta tggtcttgtc aaaatatcaa aaacaattta taataaatag ataccctgaa
    12061 aggaagagaa tcatgaactt agaagaattg aaaaaacgac aggggaagat ccgtaacttc
    12121 tctattatcg cccatattga ccacgggaaa tcaactctag cagaccgcat tttggaaaaa
    12181 acagagacgg tttcaagtcg tgaaatgcag gcccagcttt tggatagcat ggatctagag
    12241 cgggaacgtg gaattactat taagttgaat gccatcgagt tgaattacac tgcaaaagat
    12301 ggggaaactt atattttcca cttgattgac acaccagggc acgttgactt tacctatgaa
    12361 gtttcacgtt cgctagctgc ctgtgagggt gctattttgg tggtcgatgc ggctcaagga
    12421 attgaggctc aaactcttgc caacgtttat ctggctttgg ataatgattt ggaaatcatg
    12481 cctatcatta ataaaattga cctgccggct gcagatccgg agcgcgtgcg tacagagatt
    12541 gaagatgtga ttggtttgga tgccagtgaa gcagttttgg cttctgccaa ggctggtatt
    12601 gggattgaag aaatcctcga gcaaattgta gaaaaagtac cagcaccaac gggtgatgtg
    12661 acggcgccac ttaaggcctt gattttcgac tctgtttacg atgcttaccg tggggttatc
    12721 ctccaagtgc gtgtcatgga cggagtggtc aaacctggtg ataagattca gctcatgagc
    12781 aatagtaaga cctttgatgt ggccgaagtc ggtattttta caccaaaagc ggttggtcgt
    12841 gatttccttg cgactggtga tgttggttac attgcggcgt ctatcaagac ggttcaggat
    12901 actcgtgtgg gtgataccgt taccttggca accaatcctg cggcagaacc attacatggt
    12961 tataagcaga tgaatcctat ggtctttgcg ggtctctacc caatcgaatc aaacaagtac
    13021 aatgacctgc gtgaagcgct tgaaaaattg caactgaatg atgctagtct tcagtttgaa
    13081 ccagaaacat ctcaggcact tggatttggt ttccgttgtg gatttcttgg acttctccat
    13141 atggatgtta ttcaggaacg tttagagcgt gagttcaata ttgacctcat catgacagct
    13201 ccgtctgtta tttacaaagt taatttgacc gacggtgagt ctatggatgt gtctaaccca
    13261 tctgagtttc cagacccaac taagattgcg accattgaag agccttatgt caaggcgcaa
    13321 atcatggtac cacaggagtt cgtcggagca gtaatggagc tagctcagcg taagcgtggg
    13381 gactttgtga ctatggacta tattgatgat aaccgtgtca atgttatcta tcaaattcct
    13441 cttgctgaaa ttgtctttga cttctttgat aaacttaagt cttcgacacg tggttatgca
    13501 agctttgact acgaattatc agaatatcgc ccatctaagc tggtgaaaat ggatatcctt
    13561 ctcaatggag ataaggtgga tgccctcagc tttatcgttc acaaggactt tgcctacgaa
    13621 cgtgggaaac tcatcgttga taaactcaag aaaatcatcc ctcgccaaca atttgaagtt
    13681 ccaatccaag cggctattgg acacaagatt gtcgctcgta ctgatatcaa ggcccttcgt
    13741 aagaacgtac ttgctaaatg ttatggtggt gacgtttctc gtaagcgtaa actccttgaa
    13801 aaacaaaaag ctggtaagaa acgcatgaaa tccatcggat cagttgaagt tccgcaagaa
    13861 gccttcctca gcgtcttgag tatggatgaa gaataagtta tcagaaatgc ctttccttgt
    13921 tcacaggaaa tttatataag aatcaatagt aaagcaggct tagatggtct gcttttttag
    13981 tttttatact cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtatgtatgg
    14041 ttactgactt cgtcagtttc atctacaacc tcaaaactgt gttttgagta acctgcggct
    14101 agcttcctag tttgctcttt gattttcatt gagtattaga acagaaaaat gcttggagta
    14161 tttgtttgtg tgtttatttt tatataacaa actataaaca aaacaaaaat ataaaaaaga
    14221 gacaaaaaaa gaacagaaag taattaacaa cgatttcata tagtgttata ctt
//
LOCUS       DAVHSY010000045        14055 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.046, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000045 DAVHSY010000000
VERSION     DAVHSY010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14055
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.046"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(373..2064)
                     /locus_tag="VVR43_001731"
     CDS             complement(373..2064)
                     /locus_tag="VVR43_001731"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU6150053.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGIGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2200..2646
                     /gene="argR"
                     /locus_tag="VVR43_001732"
     CDS             2200..2646
                     /gene="argR"
                     /locus_tag="VVR43_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU6150054.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDKWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2697..5231
                     /gene="mutS"
                     /locus_tag="VVR43_001733"
     CDS             2697..5231
                     /gene="mutS"
                     /locus_tag="VVR43_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU6150055.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEHISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5378..7072
                     /gene="patA"
                     /locus_tag="VVR43_001734"
     CDS             5378..7072
                     /gene="patA"
                     /locus_tag="VVR43_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEU6150056.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGIMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKVVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7403..7672)
                     /locus_tag="VVR43_001735"
                     /pseudo
     CDS             complement(7403..7672)
                     /locus_tag="VVR43_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            7864..9630
                     /gene="patB"
                     /locus_tag="VVR43_001736"
     CDS             7864..9630
                     /gene="patB"
                     /locus_tag="VVR43_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU6150057.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDISISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9769..10458
                     /locus_tag="VVR43_001737"
     CDS             9769..10458
                     /locus_tag="VVR43_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU6150058.1"
                     /translation="MARTVVGVTANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10462..10641
                     /locus_tag="VVR43_001738"
     CDS             10462..10641
                     /locus_tag="VVR43_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150059.1"
                     /translation="MEYLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10628..11977
                     /locus_tag="VVR43_001739"
     CDS             10628..11977
                     /locus_tag="VVR43_001739"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU6150060.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADSVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWETFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12101..13561
                     /locus_tag="VVR43_001740"
     CDS             12101..13561
                     /locus_tag="VVR43_001740"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU6150061.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13575..14009
                     /locus_tag="VVR43_001741"
     CDS             13575..14009
                     /locus_tag="VVR43_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU6150062.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         4107 a         2714 c         3162 g         4072 t
ORIGIN      
        1 cttcggatta cgaatgaatt tgattgctgg cattatcaat catgaactag gattctagtt
       61 ttgcaggaag tctattattt ggttaggtga attagtgaag cgtttaggca agtgtctctg
      121 gttacgacgt catggactct aaatcgatta tatttagggg tcatgactag tgaagcagtt
      181 agctagttcg catataagcg gctagcgtct aacaattagg aactttagtt ccaataactt
      241 taagattacg acgttttagg acataaatcg atcatattta tgtcctaaaa ctagtgaagc
      301 gcctagccaa agtccgaata ggatttggcg ttagttactt agattgcttt gcaatcaagt
      361 aactttggcg atttacatct tctctggcgc ttctactcca agcaagcgaa gggcttcttt
      421 gagaacgact gcggttgcgt agctgagggc tagacggctg tcgcgttctg ggctttcatc
      481 caagatacgt gtatgtgcat agtatttgtt aaaggattga gccaggctaa ttgcaaattt
      541 agcaatgata gaaggttcaa agttatctgc cgcacggttg ataatacgtg ggaagtcttg
      601 aatgagttta atgatttccc agctttcagt atcattcaag ctatagttgc cagctgtttc
      661 tggtttgaaa tcggctttgc gtaagataga ttggatacga gcgtaggcat attgaacgta
      721 aggtccagtt tcaccctcga aggataccat agcctctagg tcgaagtcgt atccatttgt
      781 acggtcggtt ttgaggtcat agaatttaat ggctccaatc ccaacagcat gtgctacttg
      841 gtctttgttt tctagttcag gatttttagc ctcgatttgg accttggcac ggctaacagc
      901 ctctgcaaca gtaggctcta gcaagatgac attcccttta cgagtagaga gtttcttccc
      961 ttcttttgta accaaaccaa aaggaacgtg agtaatgtcg tcactccagt cgtagcccat
     1021 ctcttgcaag acagctttga gctgtttaaa gtgggcagat tgttcttgac caacgacata
     1081 gatagattta gcaaattggt attcgttttt acggtagagg gctgcagcca agtcacgtgt
     1141 gatatagaga gttgcaccat cagacttctt gatgagggct ggatgttcaa ttccatattt
     1201 ctcaagattc acaacttggg caccttctga ttcaagaagt agtccttttt cagaaagaat
     1261 gtctacaact gcatccatct tatcattgta gaaggcttct ccgttatagc tgtcaaattc
     1321 aaccttcaat tcattgtaaa ggcggttaaa ttccactaaa ctttcatcgc ggaaccattg
     1381 ccaaagagcg agagcttcct catctccatt ttcaagttta cggaaccatt cgcgcgcttc
     1441 ttcatccaag ctagggtcat tttcagcttc agcgttgatg cggacataga gtttaaggag
     1501 ttcatcgatt ggatgagctt ttacagcttc ttcgtcgccc cattttttgt aggcaacaat
     1561 caacatccca aattgtttac cccagtctcc caaatggttg accttgaccg tttgataacc
     1621 gattttttgg aaaatatgtg acaagctatc tccgataaca gttgaacgca ggtggccaat
     1681 agaaaatggt ttagcgatat tcggactaga catgtcgata acaacatttt cttgtttacc
     1741 aatattttgg tcagcatagt gttctttttc agtggtaaca gcttgcaata cttgagcaga
     1801 aatggcagat ttatcaagga aaaagttaac gtaaggtcct gttgcgacaa ctttttcaaa
     1861 ggcttggctg ttcatttttt cagccagttc agccgcaatc atttgtggtg ctttacgttc
     1921 gactttggca agagaaaaag cagggaaagc gatgtcaccc atttctgagt ttttaggggt
     1981 ttccagtaac tttaaaatag cctcttggtc caggctatca atgatgctag ccaattcgct
     2041 agcaatcaat tcttttgtat tcattaagag ctcctttttg gacttttcta ctattttatc
     2101 acaattttaa agaaagaaga aaaaattttt gaaatctcct gtttttttgg tataatatgg
     2161 ttataaatat agttataaat atgcacgcaa gaggatttta tgagaaaaag agatcgtcat
     2221 cagttaataa aaaaaatgat tactgaggag aaattaagta cacaaaaaga aattcaagat
     2281 cggttggagg cgcacaatgt ttgtgtgacg cagacaacct tgtctcgtga tttgcgcgaa
     2341 atcggcttga ccaaggtcaa gaaaaatgat atggtgtatt atgtactagt aaatgagaca
     2401 gaaaagattg atttggtgga atttttgtct catcatttag aaggtgttgc aagagcagag
     2461 tttaccttgg tgcttcatac caaattggga gaagcctctg ttttggcaaa tattgtagat
     2521 gtaaacaagg ataaatggat tttaggaaca gttgctggtg ccaatacctt attggttatt
     2581 tgtcgagatc agcacgttgc caaactcatg gaagatcgtt tgctagattt gatgaaagat
     2641 aagtaaggtc ttgggagtta ctctcaagac ttatttttga aaaggagaga cagaaaatgg
     2701 cgatagaaaa gctatcaccc ggcatgcaac agtatgtgga tattaaaaag caatatccag
     2761 atgctttttt gctctttcgg atgggtgatt tttatgaatt attttatgag gatgcggtca
     2821 atgctgcgca gattctggaa atttccttaa cgagtcgcaa caagaatgcc gacaatccga
     2881 tccctatggc gggtgttccc tatcattctg cccaacagta tatcgatgtc ttgattgagc
     2941 agggttataa ggtggctatc gcagagcaga tggaagatcc taaacaagca gttggggttg
     3001 ttaaacgaga ggttgttcag gtcattacgc cagggacagt ggtcgatagc agtaagccgg
     3061 acagtcagaa taattttttg gtttccatag accgcgaagg caatcaattt ggcctagctt
     3121 atatggattt ggtgacgggt gacttttatg tgacaggtct tttggatttc acgctggttt
     3181 gtggggaaat ccgtaacctc aaggctcgag aagtggtgtt gggttatgac ttgtctgagg
     3241 aagaagaaca aatcctcagc cgccagatga atctggtact ctcttatgaa aaagaaagct
     3301 ttgaagacct tcatttattg gatttgcgat tggcaacggt ggagcaaacg gcatctagta
     3361 agctgctcca gtatgttcat cggactcaga tgagggaatt gaaccacctc aaacctgtta
     3421 tccgctacga aattaaggat ttcttgcaga tggattatgc gaccaaggct agtctggatt
     3481 tggttgagaa tgctcgctca ggtaagaaac aaggcagtct tttctggctt ttggatgaaa
     3541 ccaaaacggc tatggggatg cgtctcttgc gttcttggat tcatcgcccc ttgattgata
     3601 aggaacgaat cgtccaacgt caagaagtag tgcaggtctt tctcgaccat ttctttgagc
     3661 gtagtgactt gacagacagt ctcaagggtg tttatgacat tgagcgcttg gctagtcgtg
     3721 tttcttttgg caaaaccaat ccaaaggatc tcttgcagtt ggcgactacc ttgtctagtg
     3781 tgccacggat tcgtgcgatt ttagaaggga tggagcaacc tactctagcc tatctcatcg
     3841 cacaactgga tgcaatccct gagttggaga gtttgattag cgcagcgatt gctcctgaag
     3901 ctcctcatgt gattacagat gggggaatta tccggactgg atttgatgag actttagaca
     3961 agtatcgttg cgttctcaga gaagggacta gctggattgc tgagattgag gctaaggagc
     4021 gagaaaactc tggtatcagc acgctcaaga ttgactacaa taaaaaggat ggctactatt
     4081 ttcatgtgac caattcgcaa ctaggaaatg tgccagccca ctttttccgc aaggcgacgc
     4141 tgaaaaactc agaacgcttt ggaaccgaag aattagcccg tatcgaggga gatatgcttg
     4201 aggcgcgtga gaagtcagcc aacctcgaat acgaaatatt tatgcgcatt cgtgaagagg
     4261 tcggcaagta catccagcgt ttacaagctc tagcccaagg aattgcgacg gttgatgtct
     4321 tacagagtct ggcggttgtg gctgaaaccc agcatttgat tcgacctgag tttggtgacg
     4381 attcacaaat tgatatccgg aaagggcgcc atgctgtcgt tgaaaaggtt atgggggctc
     4441 agacctatat tccaaatacg attcagatgg cagaagatac cagtattcaa ctgattacag
     4501 ggccaaacat gagtgggaag tctacctata tgcgtcagtt agccatgacg gcggttatgg
     4561 cccagctggg ttcctatgtt cctgctgaaa gcgcccattt accgattttt gatgcgattt
     4621 ttacccgtat cggagcagca gatgacttgg tttcgggtca gtcgaccttt atggtggaga
     4681 tgatggaggc caataatgcc atttcgcatg cgaccaagaa ctctctcatt ctctttgatg
     4741 aattgggacg tggaactgca acttatgacg ggatggctct tgctcagtcc atcatcgaat
     4801 atatccatga gcacatcgga gctaagaccc tctttgcgac ccactaccat gagttgacta
     4861 gtctggagtc tagtttacaa cacttggtca atgtccacgt ggcaactctg gagcaggatg
     4921 ggcaggttac cttccttcac aagattgaac cgggaccagc tgataaatcc tacggtatcc
     4981 atgttgccaa gattgctggc ttgccagcag accttttagc aagggcggat aagattttga
     5041 ctcagctaga gaatcaagga acagagagtc ctcctcccat gagacaaact agtgctgtca
     5101 ctgaacatat ttcactcttt gatagggcag aagagcatcc tatcctagca gaattagcta
     5161 aactggatgt gtataatatg acacctatgc aggttatgaa tgtcttagta gagttaaaac
     5221 agaaactata aaaccaagac tcactagtta atctagctgt atcaaggaga cttctttgac
     5281 aattctccac ttttttgcta gaataacatc acacaaacag aatgaaaagg agctgacgca
     5341 ttgtcgctcc cttttgtcta ttttttaagg agaaagtatg ctgattcaga aaataaaaac
     5401 ctacaagtgg caggccctgg cttcgctcct gatgacaggc ttgatggttg ctagttcact
     5461 tctgcaaccg cgttatctgc aggaagtctt aggcgccctc cttactggga aatatgaagc
     5521 tatttatagt atcggggctt ggttgattgg tgtggccgta gtcggtctag ttgctggtgg
     5581 actcaatgtt gtcctcgcag cctatattgc ccaaggagtt tcatccgacc ttcgggagga
     5641 tgccttccgt aaaattcaaa ccttttctta tgctgatatt gaacaattta atgcgggaaa
     5701 tctagtcgtt cgaatgacaa atgatatcaa ccagattcag aacgttgtca tgatgacctt
     5761 ccaaattctt ttcagacttc ccctcttgtt catcggttcg tttatcctag cggttcaaac
     5821 cttaccttct ctgtggtggg tgattgttct catggtagtc ttgatttttg gtttgactgc
     5881 tgtcatgatg ggaataatgg ggcctcgttt tgccaagttt caaacccttc ttgagcgcat
     5941 caatgccatt gccaaggaaa atttacgtgg cgttcgtgtg gtcaagtcct ttgtccaaga
     6001 aaaagagcaa tttgctaagt ttacagaggt ctcagacgag cttcttggtc aaaaccttta
     6061 cattggttat gccttttcag tagtggaacc ctttatgatg ttggttggtt acggggcggt
     6121 cttcctctct atttggctgg tcgcgggaat ggttcagtcg gatccgtctg ttgttggttc
     6181 catcgcttct tttgttaatt acctaagcca gattatcttt accattgtta tggttggatt
     6241 tttgggaaat tctgtcagcc gtgccatgat ttccatgcgt cgtattcgag aaattcttga
     6301 cgcagagcca gctatgacct tcaaggatat cccagatgaa gagttggttg gaagtcttag
     6361 ctttgaaaat gtgaccttta cctatccaat ggacaaggaa ccgatgctga aagttgtgag
     6421 ctttactatt gaacctggtc aaatggttgg tgtagttgga gcgactggtg caggaaagtc
     6481 aaccttggct caattgattc cacgtctctt tgatccacag gacggggcca ttaaaatcgg
     6541 tggcaaggat attcgagaag tgagtgaagg aaccctgcgt aaaacagttt ccatcgttct
     6601 ccaacgtgcc attcttttta gtggaacgat tgcagataac ttgagacagg ggaaggggaa
     6661 tgctactcta tttgaaatgg agcgcgcagc caatattgcc caggctagtg aattcattca
     6721 tcgtatggag aaaacctttg aaagtccagt tgaagaacgg ggaaccaatt tctctggtgg
     6781 acaaaaacaa aggatgtcga ttgcgcgtgg gattgtcagc aatccacgta ttctgatttt
     6841 tgatgattcg acctcagcct tggatgccaa atcagagcgc ttggtgcaag aagctttgaa
     6901 taaggacttg aaggggacga caaccattat tattgctcaa aaaattagct cggttgtcca
     6961 tgcagacaag atcttggttc taaatcaagg acgattgatt ggtcaaggta cgcatgcaga
     7021 cttggttgcc aacaatgccg tttaccgtga aatctatgaa acacagaaat gaaagacaaa
     7081 ctataagaaa agtcaatagt tttatctaaa ctatttctta tttcaatttg atgatttggc
     7141 gatgatttta gagcacggca aaaggccctt gaaaaagtcc attttttcaa aggtaatcct
     7201 gtgttaattt cagaaattac atcacttttt gttcgtcaaa tggcagctct ttttttagga
     7261 tataaaacag ggttcggata agtttttttg caaggtggat gatggctaca ttgtaatgtt
     7321 ttccttgttc taatttagtc ttaagatagg ccttaaaagc aggcgaaaag cgagggcatg
     7381 ctttggcagc ttgtatgagt acctaccgca gatgagggga actccgtttg accattcttc
     7441 ctgctaaatc aatctgatct gactgataaa tagaagaatc cagtccagcg aaagcttgta
     7501 attgagcagg attatcaaag gcatgaatat ttcgaatctc agctaaaatg accgccccta
     7561 aacgatcccc aatcccagta accgtcgtga tgaccgagtt gaactcagcc atcaagtcat
     7621 tgacacatgt ttccgccttg tcaatgagcc tcttgtaatg tttgatgttt tcattacacg
     7681 agataaaacg tctatgcgtt atcaaactca ttaccaatta aaacaaaaag ctgtggttag
     7741 atcctttcgg aaattgtcaa gcgattggag gaaatgaact aatccacagc ggcttattcc
     7801 aagtatacca cttgggcttt ggcagtagct aactgcgcta aatataatat aaggaggagt
     7861 aaaatgaaga cagttcaatt tttttggcat tattttaagg tctacaagtt ctcatttgta
     7921 gttgtcatcc tgatgattgt tctggcgact tttgcccaag ccctctttcc agtcttttct
     7981 ggacaagcgg tgacgcagct agccaattta gttcaagctt atcaaaatgg caatccagaa
     8041 cttgtatggc aaagcctatc aggaatcatg gtcaatcttg gcctgctggt tttggttcta
     8101 tttatctcta gtgtaatata catgtgtctc atgacgcgcg tgattgcaga atcgaccaac
     8161 gagatgcgca aaggcctctt tggtaagctt gctcagttga cggtttcttt ctttgaccgt
     8221 cgacaagatg gcgatatcct gtctcatttt accagtgatt tggataatat cctccaagcc
     8281 tttaacgaaa gcttgattca ggtcatgagc aatattgttt tatacattgg tctgattctt
     8341 gtcatgtttt cgagaaatgt gacgctggct ctcatcacca ttgccagcac cccattggct
     8401 ttccttatgc tgattttcat cgtgaaaatg gcacgcaaat acaccaacct ccagcagaaa
     8461 gaggtaggga agctcaacgc ctatatggat gagagcatct caggccaaaa agccgtgatt
     8521 gtgcaaggaa ttcaagagga tatgatggca ggatttcttg aacaaaatga gcgcgtgcgc
     8581 aaggcaacct ttaaaggaag aatgttctca ggaattcttt tccctgtcat gaatgggatg
     8641 agcctgatta atacagccat cgtcatcttt gctggttcgg ctgtactttt gaatgataag
     8701 tctattgaaa caagtacagc cctaggtttg attgttatgt ttgcacaatt ttcacagcag
     8761 tactaccagc ctattatcca agttgcagcg agttggggaa gccttcagtt ggcctttact
     8821 ggagctgaac gaattcagga aatgtttgat gcagaggagg aaatccgacc tgaaaaggct
     8881 ccaaccttca ctaagttgca agaaagtgtt gaaatcagtc atatcgattt ttcatacttg
     8941 cctgataaac ctattttgaa agatatcagc atttctgccc ctaaaggcca gatgacagca
     9001 gttgttgggc cgacaggttc aggaaaaacg actattatga acctcatcaa tcgcttttat
     9061 gatgttgatg ctggtggtat ttattttgat ggtaaagaca ttcgtggcta tgatttagat
     9121 agtcttagaa gcaaggtggg aattgtattg caagattcgg tcttgtttag cggaacgatt
     9181 cgagacaata tccgatttgg tgtgccagat gctagtcagg aaatggttga ggtagcagca
     9241 aaagcaaccc acattcacga ctatatcgaa agtttgcctg ataagtacga tactcttatt
     9301 gatgatgacc agagcatctt ttcaacaggg cagaagcaat tgatttcaat cgctcgaacc
     9361 ctgatgacag atccagaagt tctcattctc gatgaagcaa cttcaaacgt agatacggtg
     9421 acagaaagca agattcagca tgccatggag gtggttgtag caggtagaac tagtttcgtc
     9481 attgcccacc gcttgaaaac cattctcaat gcagatcaga ttattgtcct taaagatgga
     9541 gaagtcattg aacgtggtaa ccaccatgaa cttttgaagc taggtggctt ttattcagaa
     9601 ctctatcaca atcaatttgt tttcgaataa gaaagaagtt gtcctatgtg ggcagctttt
     9661 tcttgtccat aaaaaatgtt tatcacagcc ttaaaaaaaa catattagac gaaagtcatt
     9721 ttgagtgata tgataggact atcgttagca ttcgaaagga gaggcatcat ggctagaacg
     9781 gttgtaggag ttactgcaaa tctatgtccc gtagacgcag aaggcaaaat cattcattca
     9841 tctgtatctt gtagattcgc agagatcatt cgtcaagtcg gtggtctccc tttagtcatt
     9901 cctgttggtg atgagtcagt tgtacgtgat tatgtggaaa tgattgacaa actcattttg
     9961 acaggaggcc aaaatgttca tcctcagttt tatggagaga aaaagaccgt cgagagcgat
    10021 gattacaatc tggtccgtga cgaatttgaa ttggcactct tgaaggaagc gcttcgtcag
    10081 aataaaccaa ttatggcaat ctgtcgcggt gtccaacttg tcaatgttgc ctttggtgga
    10141 accctcaatc aagaaatcga aggtcactgg caaggactac ctttcgggac atctcactct
    10201 attgagacag tagaaggaag cgtggtggct aagctatttg ggaaagaaag tcaggtcaat
    10261 tcagtccatc gtcaaagcat taaagatttg gcacccaatt tccgtgtaac tgctattgat
    10321 tcaagagacc aaactattga agcgattgag tctatcgacg agcaccgcat tatcggttta
    10381 cagtggcatc cagagtttct ggttaatgaa gaagatggca atttagaatt atttgagtat
    10441 ttattgaatg aactgtaacg attggaatat ctggtcgttc tttcttttat tttttcaaaa
    10501 tttttagaat gtggtatttt acgcaaacgt ttgaattctg ataaaaattg gagaaattcg
    10561 acaaaaaaac ttgaaaaaaa cgaaggtaag cgttatgata gaaaagaaga aatattggag
    10621 gaagaacatg tcacatatta aatttgatta ttcaaaagtt ttagacaaat ttgttgcacc
    10681 acatgaagtg gaatacatgc aatcacaagt aacagcagca gatgaattga tccgtaaagg
    10741 aactggtgct ggtagcgact tcttgggatg gttggacctt cctgaaaaat acgaccgcga
    10801 agaatttgac cgcatcttga aagctgctga gcaaatcaag tcagacagcg atgttttggt
    10861 tgtgatcggt attggtggat cttaccttgg tgcaaaagca gcaatcgact tcttgaatca
    10921 ccattttgct aacttgcaaa caaaagaaga acgcaaagct ccacaaatcc tttacgcagg
    10981 aaactcaatc tcatctactt accttgctga ctcggtagag tatgttgcag acaaagactt
    11041 ctcagtaaac gtaatttcta aatcaggtac aacaactgaa ccagcgattg ctttccgtgt
    11101 ctttaaagaa ctcttggtta agaaatacgg tcaagaagaa gctaacaaac gtatctatgc
    11161 aacaactgac cgccaaaagg gtgctgttaa ggttgaagca gacgctaacg gttgggaaac
    11221 atttgttgtt ccagatgata tcggtggacg cttctcagta ttgacagccg ttggtttgct
    11281 tccaatcgca gcatcaggag ctgacatcaa agctcttatg gaaggtgcga atgcagctcg
    11341 caaagactac acttcagaca aaatctctga aaacgaagct taccaatacg cagctgttcg
    11401 taacatcctt tatcgtaaag gctatgcaac tgagatcttg gtaaactatg agccatcact
    11461 tcaatacttc tcagaatggt ggaaacaatt ggctggtgaa tcagaaggaa aagaccaaaa
    11521 aggtatctac ccaacttcag ccaacttctc aactgacttg cactcacttg gtcaatttat
    11581 ccaagaagga actcgtatca tgtttgaaac agttgtccgt gttgacaaac ctcgtaaaaa
    11641 cgtgcttatt cctactttgg aagaagacct tgacggactt ggttaccttc aaggaaaaga
    11701 cgttgacttt gtaaacaaaa aagcaactga cggtgttctt cttgcccaca cagatggtga
    11761 tgtaccaaac atgtatgtga ctcttccaga gcaagacgct ttcactcttg gttacactat
    11821 ctacttcttc gaattggcaa ttgccctttc aggttacttg aatgctatca acccatttga
    11881 ccaaccaggt gttgaagctt ataaacgtaa catgtttgcc cttcttggaa aaccaggatt
    11941 tgaagaattg agcaaagaac ttaacgcacg tctataatag aagaaaagag tggtttaccc
    12001 actcttttta ctctctttat ccatagaaat tggactcagt caagacttgt gatataatat
    12061 agaaagcaaa aaggcagatg cctagataat aggagaaact atgtcaaaag atatccgcgt
    12121 acgttacgca ccaagtccaa caggactact acacatcgga aatgctcgta cagcattgtt
    12181 taattacttg tatgcgcgcc atcatggtgg aacatttctc atccgtatcg aagatactga
    12241 ccgtaaacgc catgtcgagg atggtgaacg ttcacaactt gaaaaccttc gctggttagg
    12301 catggattgg gatgaaagtc cagaatcaca tgagaattat cgccagtctg agcgtttaga
    12361 cttgtatcaa aaatacattg accaactatt agctgaagga aaagcctata aatcttacgt
    12421 tacagaagaa gagttggcag ctgaacgcga acgccaagaa gtagctggcg aaacaccacg
    12481 ctacatcaat gaataccttg gtatgagtga agaagaaaaa gcagcttaca tcgcagaacg
    12541 tgaagcagca gggatcatcc caactgttcg tttggctgtc aatgagtcag gtatctacaa
    12601 gtggcatgat atggtcaaag gcgatatcga atttgaaggt ggcaatatcg gtggtgactg
    12661 ggttatccaa aagaaagacg gttacccaac ttacaacttt gccgttgtta tcgatgacca
    12721 cgatatgcaa atctctcatg ttatccgtgg agatgaccat attgctaata caccaaaaca
    12781 gcttatggtc tatgaagctc ttggttggga agctccagag ttcggtcaca tgaccttgat
    12841 tatcaactct gagactggta agaagttatc taaacgtgat actaatacac ttcaatttat
    12901 cgaagattac cgaaagaaag gttaccttcc agaagcagtc tttaacttta ttgctcttct
    12961 tggttggaac ccaggtggtg aagatgagat tttctctcgt gaagaactca ttaaactttt
    13021 tgatgaaaac cgcctcagca agtcaccagc agcctttgat cagaaaaaac tagactggat
    13081 gagcaatgat tatatcaaga atgcagacct tgaaaccatc tttgaaatgg caaaaccatt
    13141 cttagaggaa gcaggccgtt tgactgacaa ggctgaaaaa ttagttgagc tctataaacc
    13201 acaaatgaaa tcagtagatg agattatccc attgacagat cttttcttct cagatttccc
    13261 agaattgaca gaagcagagc gcgaagtcat gacgggtgaa acagttccaa cagttcttga
    13321 agcattcaaa gcaaaacttg aagcgatgac agatgataaa tttgtgacag aaaatatctt
    13381 cccacaaatt aaagcagttc aaaaagaaac aggtattaaa gggaaaaatc ttttcatgcc
    13441 tattcgtatc gcagtttcag gcgaaatgca tgggccagaa ttaccagata caattttctt
    13501 gcttggacgt gaaaaatcaa ttcagcatat cgaaaacatg ctaaaagaaa tctctaaata
    13561 aagaggatac aataatggac atctgggaaa agatgtacga agaagcacag aaactataca
    13621 atccacatga agtatcagac tttgtttatg ccaatcatgt tgtagctgca gtagaagcag
    13681 aagatggaca aatatttaca ggattctgta tggagggaac ctgtggtgtt ttccatctct
    13741 gcgcagaacg ggcggccctc ttcaatatgt accaattttc aggacaaact aaggttaaga
    13801 aagtattagc ctttcgagac aaaccacctt atggtggaag ttcagccatg ccttgcggtg
    13861 cttgtagaga attcctttta gaacttaatg ctgaaaataa agatgcagaa ttcatgatgg
    13921 actataatat aagaaaaaca gttaaagtcg cagaactaat cccttattgg tggggagaag
    13981 aacgtgcttc taagtttaat gagcgataga agagtcagta taattttggc tctttttact
    14041 ataagttgaa aaaat
//
LOCUS       DAVHSY010000046        13284 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.047, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000046 DAVHSY010000000
VERSION     DAVHSY010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.047"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            206..2866
                     /gene="rrgA"
                     /locus_tag="VVR43_001742"
     CDS             206..2866
                     /gene="rrgA"
                     /locus_tag="VVR43_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus tip adhesin RrgA"
                     /protein_id="HEU6150063.1"
                     /translation="MKKVRKIFQKAVAGLCCISQLTAFSSIVALAETPETSPAIGKVV
                     IKETGEGGALLGDAVFELKNNTDGTTVSQRTEAQTGEAIFSNIKPGTYTLTEAQPPVG
                     YKPSTKQWTVEVEKNGRTTVQGEQVENREEALSDQYPQTGTYPDVQTPYQIIKVDGSE
                     KNGQHKALNPNPYERVIPEGTLSKRIYQVNNLDDNQYGIELTVSGKTVYERKDKSVPL
                     DVVILLDNSNSMSNIRNKNARRAERAGEATRSLIDKITSDPENRVALVTYASTIFDGT
                     EFTVEKGVADKNGKRLNDSLFWNYDQTSFTTNTKDYSYLKLTNDKNDIVELKNKVPTE
                     AEDHDGNRLMYQFGATFTQKALMKADEILTQQARQNSQKVIFHITDGVPTMSYPINFN
                     HATFAPSYQNQLNAFFSKSPNKDGILLSDFITQATSGEHTIVRGDGQSYQMFTDKTVY
                     EKGAPAAFPVKPEKYSEMKAVGYAVIGDPINGGYIWLNWRESILAYPFNSNTAKITNH
                     GAPTRWYYNGNIAPDGYDVFTVGIGINGDPGTDEATATSFMQSISSKPENYTNVTDTT
                     KILEQLNRYFHTIVTEKKSIENGTITDPMGELIDLQLGTDGRFDPADYTLTANDGSRL
                     ENGQAVGGPQNDGGLLKNAKVFYDTTEKRIRVTGLYLGTGEKVTLTYNVRLNDQFVSN
                     KFYDTNGRTTLHPKEVEKNTVRDFPIPKIRDVRKYPAITIAKEKKLGEIEFIKINKND
                     KKPLRDAVFSLQKQHPDYPDIYGAIDQNGTYQNVRTGEDGKLTFKNLSDGKYRLFENS
                     EPAGYKPVQNKPIVAFQIVNGEVRDVTSIVPQDIPAGYEFTNDKHYITNEPIPPKREY
                     PRTGGIGMLPFYLIGCMMMGGVLLYTRKHP"
     gene            3089..5086
                     /gene="rrgB"
                     /locus_tag="VVR43_001743"
     CDS             3089..5086
                     /gene="rrgB"
                     /locus_tag="VVR43_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus major pilin RrgB"
                     /protein_id="HEU6150064.1"
                     /translation="MKSINKFLTMLAALLLTASSLFSAATVFAAGTTTTSVTVHKLLA
                     TDGDMDKIANELETGNYAGNKVGVLPANAKEIAGVMFVWTNTNNEIIDENGQTLGVNI
                     DPQTFKLSGAMPATAMKKLTEAEGAKFNTANLPAAKYKIYEIHSLSTYVGEDGATLTG
                     SKAVPIEIELPLNDVVDAHVYPKNTEAKPKIDKDFKGKANPDTPRVDKDTPVNHQVGD
                     VVEYEIVTKIPALANYATANWSDRMTEGLAFNKGTVKVTVDDVALEAGDYALTEVATG
                     FDLKLTDAGLAKVNDQNAEKTVKITYSATLNDKAIVEVPESNDVTFNYGNNPDHGNTP
                     KPNKPNENGDLTLTKTWVDATGAPIPAGAEATFDLVNAQTGKVVQTVTLTTDKNTVTV
                     NGLDKNTEYKFVERSIKGYSADYQEITTAGEIAVKNWKDENPKPLDPTEPKVVTYGKK
                     FVKVNDKDNRLAGAEFVIANADNAGQYLARKADKVSQEEKQLVVTTKDALDRAVAAYN
                     ALTAQQQTQQEKEKVDKAQAAYNAAVIAANNAFEWVADKDNENVVKLVSDAQGRFEIT
                     GLLAGTYYLEETKQPAGYALLTSRQKFEVTATSYSATGQGIEYTAGSGKDDATKVVNK
                     KITIPQTGGIGTIIFAVAGAVIMGIAVYAYVKNNKDEDQLA"
     gene            5133..6316
                     /gene="rrgC"
                     /locus_tag="VVR43_001744"
                     /pseudo
     CDS             5133..6316
                     /gene="rrgC"
                     /locus_tag="VVR43_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963222.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus minor pilin RrgC"
     gene            6655..7551
                     /gene="srtC-1"
                     /locus_tag="VVR43_001745"
     CDS             6655..7551
                     /gene="srtC-1"
                     /locus_tag="VVR43_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-1"
                     /protein_id="HEU6150065.1"
                     /translation="MAKTKKQKRNNLLLGVVFFIGMAVMAYPLVSRLYYRVESNQQIA
                     DFDKEKATLDEADIDERMKLAQAFNDSLNNVVSGDPWSEEMKKKGRAEYARMLEIHER
                     MGHVEIPAIDVDLPVYAGTAEEVLQQGAGHLEGTSLPIGGNSTHAVITAHTGLPTAKM
                     FTDLTKLKVGDKFYVHNIKEVMAYQVDQVKVIEPTNFDDLLIVPGHDYVTLLTCTPYM
                     INTHRLLVRGHRIPYVAEVEEEFIAANKLSHLYRYLFYVAVGLIVILLWIIRRLRKKK
                     RQSERALKALKEATKEVKVEDE"
     gene            7544..8437
                     /gene="srtC-2"
                     /locus_tag="VVR43_001746"
     CDS             7544..8437
                     /gene="srtC-2"
                     /locus_tag="VVR43_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-2"
                     /protein_id="HEU6150066.1"
                     /translation="MSKSRYSRKKSVKKKKNPFILLLIFLVGLAVAMYPLVSRYYYRI
                     ESNEVIKEFDETVSQMDKAELEERWRLAQAFNATLKPSEILDPFTDQEKKQGVSEYAN
                     MLKVHERIGYVEIPAIEQEIPMYVGTSEDILQKGAGLLEGASLPVGGENTHTVITAHR
                     GLPTAELFSQLDKMKKGDIFYLHVLDQVLAYQVDQIVTVEPNDFEPVLIQHGQDYATL
                     LTCTPYMINSHRLLVRGKRIPYTAPIAERNRAVRERGQFWLWLLLGAMAVILLLLYRV
                     YRNRRIVKGLEKQLEGRHVKD"
     gene            8424..9275
                     /gene="srtC-3"
                     /locus_tag="VVR43_001747"
     CDS             8424..9275
                     /gene="srtC-3"
                     /locus_tag="VVR43_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-3"
                     /protein_id="HEU6150067.1"
                     /translation="MSRTKLRALLGYLLMLVACLIPIYCFGQMVLQSLGQVKGHATFV
                     KSMTTEMYQEQQNHSLAYNQRLASQNRIVDPFLAEGYEVNYQVSDDPDAVYGYLSIPS
                     LEIMEPVYLGADYHHLGMGLAHVDGTPLPLDGTGIRSVIAGHRAEPSHVFFRHLDQLK
                     VGDALYYDNGQEIVEYQMMDTEIILPSEWEKLESVSSKNIMTLITCDPIPTFNKRLLV
                     NFERVAVYQKSDPQTAAVARVAFTKEGQSVSRVATSQWLYRGLVVLAFLGILFVLWKL
                     ARLLRGK"
     gene            complement(9348..10654)
                     /locus_tag="VVR43_001748"
                     /pseudo
     CDS             complement(9348..10654)
                     /locus_tag="VVR43_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10769..10918)
                     /locus_tag="VVR43_001749"
     CDS             complement(10769..10918)
                     /locus_tag="VVR43_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150068.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFMAL"
     gene            complement(10911..11195)
                     /locus_tag="VVR43_001750"
     CDS             complement(10911..11195)
                     /locus_tag="VVR43_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150069.1"
                     /translation="MVWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(11792..11962)
                     /locus_tag="VVR43_001751"
     CDS             complement(11792..11962)
                     /locus_tag="VVR43_001751"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6150070.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEKAG"
     gene            complement(12616..>13284)
                     /locus_tag="VVR43_001752"
     CDS             complement(12616..>13284)
                     /locus_tag="VVR43_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6150071.1"
                     /translation="KNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIYTSFFTKEKIGA
                     SKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFKNSQLTVLKSLV
                     KTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPADKIYINSQLLNY
                     QPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVAFFIEHSNVLQD
                     IISP"
BASE COUNT         4237 a         2115 c         2950 g         3982 t
ORIGIN      
        1 aagtgtgtca ttgccaggtt gagaagatag ctataacgca cttttatacg cttttgctac
       61 gtttgttagt gaacggatta actcagtgag ataaatttta tcagaacata agtaatccgt
      121 ttcttcgtgt atacagattg aaagtaccta tgaatcatag aaggattaac ttgttctatg
      181 aataatgctt aacagggaga cacacatgaa aaaagtaaga aagatatttc agaaggcagt
      241 tgcaggactg tgctgtatat ctcagttgac agctttttct tcgatagttg ctttagcaga
      301 aacgcctgaa accagtccag cgataggaaa agtagtgatt aaggagacag gcgaaggagg
      361 agcgcttcta ggagatgccg tctttgagtt gaaaaacaat acggatggca caactgtttc
      421 gcaaaggaca gaggcgcaaa caggagaagc gatattttca aacataaaac ctgggacata
      481 caccttgaca gaagcccaac ctccagttgg ttataaaccc tctactaaac aatggactgt
      541 tgaagttgag aagaatggtc ggacgactgt ccaaggtgaa caggtagaaa atcgagaaga
      601 ggctctatct gaccagtatc cacaaacagg gacttatcca gatgttcaaa caccttatca
      661 gattattaag gtagatggtt cggaaaaaaa cggacagcac aaggcgttga atccgaatcc
      721 atatgaacgt gtgattccag aaggtacact ttcaaagaga atttatcaag tgaataattt
      781 ggatgataac caatatggaa tcgaattgac ggttagtggg aaaacagtgt atgaacgaaa
      841 agataagtct gtgccgctgg atgtcgttat cttgctcgat aactcaaata gtatgagtaa
      901 cattcgaaac aagaatgctc gacgtgcgga aagagctggt gaggcgacac gttctcttat
      961 tgataaaatt acatctgatc cagaaaatag ggtagcgctt gtgacttatg cttccactat
     1021 ctttgatggg accgagttta cagtagaaaa aggggtagca gataaaaacg gaaaacgatt
     1081 gaatgattct cttttttgga attatgatca gacgagtttt acaaccaata ccaaagatta
     1141 tagttattta aagctgacta atgataagaa tgacattgta gaattaaaaa ataaggtacc
     1201 taccgaggca gaagatcatg atggaaatag attgatgtac caattcggtg ccacttttac
     1261 tcagaaagct ttgatgaagg cagatgagat tttgacacaa caagcgagac aaaatagtca
     1321 aaaagtcatt ttccatatta cggatggtgt cccaactatg tcgtatccga ttaattttaa
     1381 tcatgctacg tttgctccat catatcaaaa tcaactaaat gcatttttta gtaaatctcc
     1441 taataaagat ggaatactat taagtgattt tattacgcaa gcaactagtg gagaacatac
     1501 aattgtacgc ggagatgggc aaagttacca gatgtttaca gataagacag tttatgaaaa
     1561 aggtgctcct gcagctttcc cagttaaacc tgaaaaatat tctgaaatga aggcggttgg
     1621 ttatgcagtt ataggcgatc caattaatgg tggatatatt tggcttaatt ggagagagag
     1681 tattctggct tatccgttta attctaatac tgctaaaatt accaatcatg gtgcccctac
     1741 aagatggtac tataacggga atattgctcc tgatgggtat gatgtcttta cggtaggtat
     1801 tggtattaac ggagatcctg gtacggatga agcaacggct actagtttta tgcaaagtat
     1861 ttctagtaaa cctgaaaact ataccaatgt tactgacacg acaaaaatat tggaacagtt
     1921 gaatcgttat ttccacacca tcgtaactga aaagaaatca attgagaatg gtacgattac
     1981 agatccgatg ggtgagttaa ttgatttgca attgggcaca gatggaagat ttgatccagc
     2041 agattacact ttaactgcaa acgatggtag tcgcttggag aatggacaag ctgtaggtgg
     2101 tccacaaaat gatggtggct tgctaaaaaa tgcaaaagtg ttctatgata cgactgagaa
     2161 aaggattcgt gtaacaggtt tgtaccttgg aacgggtgaa aaagttacat tgacttataa
     2221 tgttcgcttg aatgaccaat ttgtaagcaa taaattctat gacacgaatg gtcgaacaac
     2281 cctacaccct aaggaagtag aaaagaacac agtgcgcgac ttcccgattc ctaagattcg
     2341 tgatgtgcga aaatatccag caattacgat tgcaaaagag aaaaaacttg gtgaaattga
     2401 gtttattaag atcaataaga atgataaaaa accactgaga gatgcggtct ttagtcttca
     2461 aaaacaacat ccggattatc cagatattta tggagctatt gatcaaaatg gcacttatca
     2521 aaatgtgaga acaggtgaag atggtaagtt gacctttaaa aatctgtcag atgggaaata
     2581 tcgattattt gaaaattctg aaccagctgg ttataaaccc gttcaaaata agcctatcgt
     2641 tgccttccaa atagtaaatg gagaagtcag agatgtgact tcaatcgttc cacaagatat
     2701 accagcgggt tacgagttta cgaatgataa gcactatatt accaatgaac ctattcctcc
     2761 aaagagagaa tatcctcgaa ctggtggtat cggaatgttg ccattctatc tgataggttg
     2821 catgatgatg ggaggagttc tattatacac acggaaacat ccgtaaagtg tagaaatgat
     2881 aatatctatg ttctgaacaa tacttttaag aagtagcact caagaagaga tttaagttta
     2941 cttggtgaaa ccagttttct tcgccaagta aaccaccatt gaaaggggag atgttttcga
     3001 aaacttgcac agaaaaagga ttattattgt catgtgtaat tcattacatt gctcacagtt
     3061 gattttaaga gataaataag gagaaatcat gaaatcaatc aacaaatttt taacaatgct
     3121 tgctgcctta ttattgacag cgagtagcct gttttcagct gcaacagttt ttgcggctgg
     3181 gacgacaaca acatctgtta ccgttcataa actattggca acagatgggg atatggataa
     3241 aattgcaaat gagttagaaa caggtaacta tgctggtaat aaagtgggtg ttctacctgc
     3301 aaatgcaaaa gaaattgccg gtgttatgtt cgtttggaca aatactaata atgaaattat
     3361 tgatgaaaat ggccaaactc taggagtgaa tattgatcca caaacattta aactctcagg
     3421 ggcaatgccg gcaactgcaa tgaaaaaatt aacagaagct gaaggagcta aatttaacac
     3481 ggcaaattta ccagctgcta agtataaaat ttatgaaatt cacagtttat caacttatgt
     3541 cggtgaagat ggagcaacct taacaggttc taaagcagtt ccaattgaaa ttgaattacc
     3601 attgaacgat gttgtggatg cgcatgtgta tccaaaaaat acagaagcaa agccaaaaat
     3661 tgataaagat ttcaaaggta aagcaaatcc agatacacca cgtgtagata aagatacacc
     3721 tgtgaaccac caagttggag atgttgtaga gtacgaaatt gttacaaaaa ttccagcact
     3781 tgctaattat gcaacagcaa actggagcga tagaatgact gaaggtttgg cattcaacaa
     3841 aggtacagtg aaagtaactg ttgatgatgt tgcacttgaa gcaggtgatt atgctctaac
     3901 agaagtagca actggttttg atttgaaatt aacagatgct ggtttagcta aagtgaatga
     3961 ccaaaacgct gaaaaaactg tgaaaatcac ttattcggca acattgaatg acaaagcaat
     4021 tgtagaagta ccagaatcta atgatgtaac atttaactat ggtaataatc cagatcacgg
     4081 gaatactcca aagccgaata agccaaatga aaacggcgat ttgacattga ccaagacatg
     4141 ggttgatgct acaggtgcac caattccggc tggagctgaa gcaacgttcg atttggttaa
     4201 tgctcagact ggtaaagttg tacaaactgt aactttgaca acagacaaaa atacagttac
     4261 tgttaacgga ttggataaaa atacagaata taaattcgtt gaacgtagta taaaagggta
     4321 ttcagcagat tatcaagaaa tcactacagc tggagaaatt gctgtcaaga actggaaaga
     4381 cgaaaatcca aaaccacttg atccaacaga gccaaaagtt gttacatatg gtaaaaagtt
     4441 tgtcaaagtt aatgataaag ataatcgttt agctggggca gaatttgtaa ttgcaaatgc
     4501 tgataatgct ggtcaatatt tagcacgtaa agcagataaa gtgagtcaag aagagaagca
     4561 gttggttgtt acaacaaagg atgctttaga tagagcagtt gctgcttata acgctcttac
     4621 tgcacaacaa caaactcagc aagaaaaaga gaaagttgac aaagctcaag ctgcttataa
     4681 tgctgctgtg attgctgcca acaatgcatt tgaatgggtg gcagataagg acaatgaaaa
     4741 tgttgtgaaa ttagtttctg atgcacaagg tcgctttgaa attacaggcc ttcttgcagg
     4801 tacatattac ttagaagaaa caaaacagcc tgctggttat gcattactaa ctagccgtca
     4861 gaaatttgaa gtcactgcaa cttcttattc agcgactgga caaggcattg agtatactgc
     4921 tggttcaggt aaagatgacg ctacaaaagt agtcaacaaa aaaatcacga tcccacaaac
     4981 gggtggtatt ggtacaatta tctttgctgt agcaggggct gtgattatgg gtattgcagt
     5041 gtacgcatat gttaaaaaca acaaagatga ggatcaactt gcttaagtaa gagagaaagg
     5101 agccattgat gacaatgcag aaaatgcaga aaatgattag tcgtatcttc tttgttatgg
     5161 ctctgtgttt ttctcttgta tggggtgcac atgcagtcca agcgcaagaa gatcacacgt
     5221 tggtcttgca attggagaac tatcaggagg tggttagtca attgccatct cgtgatggtc
     5281 atcggttgcg caggtatgga agttggatga ttcgtattcc tatgataatc gggtgcaaat
     5341 tgtgagagac ttgcattcgt gggatgagaa taaactttct tctttcaaaa agacttcgtt
     5401 tgagatgacc ttccttgaga atcagattga agtatctcat attccaaatg gtctttacta
     5461 tgttcgctct attatccaga cggatgcggt ttcttatcca gctgaatttc tttttgaaat
     5521 gacagatcag acggtagagc ctttggtcat tgtagcgaaa aaagcagata cggtgacaac
     5581 aaaggtgaag ctgataaagg tggatcaaga ccacaatcgc ttggagggtg tcggctttaa
     5641 attggtatca gtagcaagag atggttctga aaaagaggtt cccttgattg gagaataccg
     5701 ttacagttct tctggtcaag tagggagaac tctctatact gataaaaatg gagagattgt
     5761 tgtgacaaat cttcctcttg ggacctatcg tttcaaggag gtggagccac tggcaggcta
     5821 tactgttacg acgatggata cggatgtcca gttggtagat catcagctgg tgacgattac
     5881 ggttgtcaat cagaaattac cacgtggcaa tgttgacttt atgaaggtgg atggtaggac
     5941 caatacctct cttcaagggg caatgttcaa agtcatgaaa gaagaaaacg gacactatac
     6001 tcctgttctt caaaatggta aggaagtagt tgtggcatca gggaaagatg gtcgtttccg
     6061 agtggaaggt ctagagtatg ggacatacta tttatgggag ctccaagctc caactggtta
     6121 tgttcaatta acatcgcctg tttcctttac aatcgggaaa gatactcgta aggaactggt
     6181 aacagtggtt aaaaataaca agcgaccacg gattgatgtg ccagatacag gggaagaaac
     6241 cttgtatatc ttgatgcttg ttgccatttt gttgtttggt agtggctatt atcttacgaa
     6301 aaaaacaaat aactgatatt caatgtacat cattatgaaa aagatagcag gctgaaggga
     6361 agaccagagt actctgaggt gatgttaatc aggaatcatg gtgatttggc atgaatcata
     6421 ataacggata tgaggctggg cagattgtgc cagcctcatt gtgggttatt gtttgtaaaa
     6481 cgataggact ggtctggtaa tcattttagg aatggacagg actgggattc tgatttaaaa
     6541 tggatggtga atcagaaaga aatgagattt tctcgtttct cttagcagat aggattgtct
     6601 gttaggaaaa gcgataaaat gatgagtttg aagttaaagg aatgctgata aaaaatggca
     6661 aaaacaaaaa agcaaaaacg aaacaatctc ctattaggag tggtattttt cattggaatg
     6721 gcggtaatgg cgtatccgct ggtgtctcgc ttgtattatc gagtggaatc aaatcaacaa
     6781 attgctgact ttgataagga aaaagcaacg ttggatgagg ctgacattga tgaacgaatg
     6841 aaattggcac aagccttcaa tgactctttg aataatgtag tgagtggcga tccttggtcg
     6901 gaagaaatga agaaaaaagg gcgagcagag tatgcacgca tgttagaaat ccatgagcgg
     6961 atggggcatg tggaaatccc tgctattgat gtagatttgc cggtttatgc tggtactgct
     7021 gaagaggtat tgcagcaagg cgctggacat ctagagggaa cttctctacc gatcggaggc
     7081 aattcgaccc atgcggtgat tacggcacat acaggtttgc caacggctaa gatgtttacg
     7141 gatttgacca aacttaaagt tggggataag ttttatgtgc acaatatcaa ggaagtgatg
     7201 gcctatcaag tggatcaagt aaaggtgatt gagccgacga actttgatga tttattgatt
     7261 gtaccaggtc atgattatgt gaccttgctg acctgtacgc catacatgat caatacccat
     7321 cgtctattgg ttcgggggca tcggataccg tacgtagcag aggttgagga agaatttatt
     7381 gcggcaaaca aactcagtca tctctatcgc tacctgtttt atgtggcagt tggtttgatt
     7441 gtgattcttt tatggattat tcgacgcttg cgcaagaaga aacggcaatc agaaagagct
     7501 ttgaaagcat tgaaggaagc tactaaggaa gtgaaggtag aggatgagta agagtagata
     7561 ttcacggaaa aagagcgtga aaaagaagaa aaatccgttc attcttcttc tgattttttt
     7621 ggtggggctt gccgttgcga tgtatccctt ggtgtctcgt tattattatc gtattgagtc
     7681 aaacgaggtt attaaagagt ttgatgagac ggtttcccag atggataagg cggaacttga
     7741 ggagcgttgg cgcttggctc aagccttcaa tgcgaccttg aaaccatctg aaatcctcga
     7801 tccttttaca gatcaggaaa agaaacaggg agtttcagaa tatgctaaca tgctaaaagt
     7861 tcatgagcgt atcggatatg tagaaattcc tgcgattgaa caggaaatcc ccatgtatgt
     7921 tggcacaagt gaagacattc ttcagaaagg ggcagggctg ttagaagggg cttcgctgcc
     7981 tgttggaggt gaaaataccc atacagtgat cactgctcac agaggattgc caacggcaga
     8041 attgttcagt caattggata agatgaagaa aggggatatc ttttatcttc acgttttaga
     8101 ccaggttttg gcctatcaag tggatcagat agtgacggtg gagccgaatg attttgagcc
     8161 tgttctgatt caacatggac aagattatgc gactttactg acttgtacgc catacatgat
     8221 taacagccac cgtttgttgg tacgtgggaa acggattcca tatacagcgc cgattgctga
     8281 gcggaatcga gcggtgagag agcgtgggca attctggttg tggttattac taggagcgat
     8341 ggcggtcatc cttctcttgc tgtatcgcgt gtatcgtaat cgacggattg tcaaaggact
     8401 agaaaagcaa ttggaggggc gtcatgtcaa ggactaaact acgagcctta ttgggatact
     8461 tgttgatgtt ggtagcctgt ttgattccta tttattgttt tggacagatg gtgttgcagt
     8521 ctcttggaca ggtgaaaggt catgctacat ttgtgaaatc catgacaact gaaatgtacc
     8581 aagaacaaca gaaccattct ctcgcctaca atcaacgctt ggcttcgcaa aatcgcattg
     8641 tagatccttt tttggcggag ggatatgagg tcaattacca agtgtctgac gaccctgatg
     8701 cagtctatgg ttacttgtct attccaagtt tggaaatcat ggagccggtt tatttgggag
     8761 cagattatca tcatttaggg atgggcttgg ctcatgtgga tggtacaccg ctgcctctgg
     8821 atggtacagg gattcgctca gtgattgctg ggcaccgtgc agagccaagc catgtctttt
     8881 tccgccattt ggatcagcta aaagttggag atgctcttta ttatgataat ggccaggaaa
     8941 ttgtagaata tcagatgatg gacacagaga ttattttacc gtcggaatgg gaaaaattag
     9001 aatcggttag ctctaaaaat atcatgacct tgataacctg cgatccgatt cctaccttta
     9061 ataaacgctt attagtgaat tttgaacgag tcgctgttta tcaaaaatca gatccacaaa
     9121 cagctgcagt tgcgagggtt gcttttacga aagaaggaca atctgtatcg cgtgttgcaa
     9181 cctctcaatg gttgtaccgt gggctagtgg tactggcatt tctgggaatc ctgtttgttt
     9241 tgtggaagct agcacgttta ctacgaggga aataaaaaga aatgaaagga aagctaaggc
     9301 tgttcctttt tccggctctt tgtcaactgt agtgggttga agaaaagcta agcttgagaa
     9361 aggacaaatt tcgtcctttc ttttttgatg ttcaaagcga taaaaatccg ttttttgaag
     9421 ttttcaaagt tccgaaaacc aaaggcattg cgcttgataa gtttgatgag attattggtc
     9481 gcttccagtt tggcattaga atagtgtagt tgaagggcgt tgacaatctt ttctttatct
     9541 ttgaggaagg ttttaaagac agtctgaaaa ataggatgaa cctgctttag attgtcctca
     9601 ataagcccga aaaatttctc tggttcctta ttctggaagt gaaacagcaa gagttgatag
     9661 agttgatagt ggtgtttcaa gtcttccgaa tagctcaaaa gcttgtttaa aatctcttta
     9721 ttggttaagt gcatacgaaa agtaggacga taaaaatgtt tatcgctgag tttacgacta
     9781 tcctgttgaa tgagtttcca gtagcgcttg atagccttgt attcatggga ttttcgatga
     9841 aactgattca tgatttgaac acgcacacga ctcatagcac ggctaagatg ttgtacaatg
     9901 tgaaagcgat caagaacaat ttttgcattc gggagtgaaa cagtctggga gactgtttca
     9961 gcctgagcct agaaatttga aagcgaagct gtttagccaa gtcatagtaa gggctaaaca
    10021 tatccatagt aatgattttg acgcgacatc ggacaactct atcgtagcga agaaagtgat
    10081 ttcgaatgat agcttgtgtt ctaccctcaa gaacagtgat gatattgaga ttgttaaaat
    10141 cttgcgcaat gaagctcatc tttccctttg taaaagcata ctcatcccaa gacataatct
    10201 caggaagacg cgaaaaatca tgtttaaagt gaaaatcatt gagctttcga atgacagttg
    10261 aagttgaaat ggccagctga tgggcaatat cggtcataga aatcttttca attaactttt
    10321 gcgcaatctt ttggttgata atacgaggaa tttggtgatt tttcttgacg atagaagttt
    10381 cagcgaccat cattttcaag caatgatagc acttaaaacg acgttttcta aggagaattc
    10441 tagaaggcat accagttgtt tcgaggtaag ggatcttaga cggtttttga aagtcatatt
    10501 tcttcaattg gtttccgcac tcagggcaag atggggcgtc gtagtccagt ttggcgatga
    10561 tttccttgtg tgtatcttta ttgatgatgt ctgaaatctg gatattaggg tctttaatgt
    10621 ctagtaattt tgtgataaaa tgtaattgtt ccatatgatt ctttctaatg agttgttttg
    10681 tcgcttttca ttataggtca tatgggactt tttttctaca caaaataggc tccataatat
    10741 ccataggggg ggttacccac tacaaatatt atagagccat aaaagcatca acatcttgtg
    10801 tggcacgtaa accatgatat tctaagacat aaccatcgac acagataatt gttaaagtca
    10861 gattttcctg aattaattcc ttatttaggg cttggaagac cggtttcatt ttatccatgt
    10921 ttgtatttct ccatcaattt ttgaacattg gttaacttag caggtttatt taatgaaatc
    10981 acatatttat gagttggagt atgctcttga aaggcatact tcaagctaat tttttgaaaa
    11041 cgggttagtt ctttggagtc tagcaacttt tctacatctt ggtttgttaa ataagaatag
    11101 tcttcaaaaa taacttttcg caaatagcga aaccaatggc ttgcgttgaa ttgtgattgt
    11161 ttggatgcct gtatcatata atcgtaccaa accattgttt tcctcctata aaatttagtt
    11221 tatattcaaa aatgtagttt ttcttaatta gctcgtatct ataggatgat actgaaaatc
    11281 ttcttgttgc tttaaatcac aatcgaaaaa ttctgttttt catcttagaa aagaatgttt
    11341 agaaatgtaa aatgaacctt ttttcttatc cgaaaacctt actaaagtat ataatttagg
    11401 aagtcaattc tgtatgataa tgtttgtact atcgtcgagt ttttgcttga ttgcctaacg
    11461 agataaattt tagaagaatt ttcggtgtga tttgacaagc ttctgactgg aaggatagtt
    11521 acactagtat tgtttattaa aatgagcaga tagagaaaat ttggaatcta tttgcttatt
    11581 atcaatcgtt tttttagctt atttgtctta gattggtata gaactgatct atggattaat
    11641 cctcttgtat cttatcctgt tcctaaatat gttggtagaa aaatgaagca gttgttacga
    11701 gtgtctgtat tgggaaaaat tttgtctata caattcttta aatgatatga aggctaggaa
    11761 tgccaaaaca ctgacatatt tcgtttaaag cctatccagc cttttcaatt gtatttgtag
    11821 aaatgctatc agtaatatat tcgcgaacac tatgatttac aacagtgtgg tcgtacatct
    11881 ttgtaacttt attatacaac aaccatttac aggtgtaaag ttgagcagtg tctttagtaa
    11941 atttagggac ttgttttgtc atagttttga tacctgtatt cgttgtttca tgagtatttg
    12001 acgtttcttt tcatgtaggc atttcaacaa ttagaatgat atttttccga ggatgaactt
    12061 atatattgtg actttttaga gttatgatgc ctcttgattt gactatcgct atcaatttca
    12121 tccactttta cagtttcatg gttttatgaa ccgaaacatc taggtacagg ttttagcatc
    12181 aattgattgt ttttgagcca tatgaagttg aaacgtggag atgcttttct tgtgataacg
    12241 ccctattcaa agaggcataa ccgtttttgg agagagttca gtactatgtg gcgctaaata
    12301 ctatatgtaa aacatatatt aaacaagatt taactaagga gaattgtaaa aacaaaaatg
    12361 agaatttcat ataaagttta ttctaggagt atgtatcttg aataaaaatt gttatttaag
    12421 ttctgggggt tatgatgaat gtttttataa taataaaatg cagctagaag aaaagttatt
    12481 ttaatataaa tcactcaaca tagcgagaag gcggtttcct atatggaagt cgtcttgttt
    12541 tcatattgtc taaatacgag atatttacta caggttatag ttgatttaaa caggtgtata
    12601 gatttctaat atatattaag gtgaaataat atcttgtaat acattgctat gctctatgaa
    12661 aaaagcaacg atagctaatg cacaagctcc tatacttcca cgatgtttgt tgtaaggtaa
    12721 aatttcaatt tctatattac gagtaaaggg aacgaagtgg agctggtctt ggattttatc
    12781 cctgacttca tgagtgaaag gttgataatt aagcaattga ctgttgatat agattttatc
    12841 agcaggattg atgaggagaa gatttgcaat agaagtggcc aataaattga ctcctttatc
    12901 aatttgttgg cgtaaagcgg agtcgcctaa attataagcc gttaaaaggg tgtctaaatg
    12961 aatgtctttt tcagtcttta caaggctttt tagtacagtt agttgggaat ttttaaataa
    13021 taattgggcg tgtttgatta accaagcatc cgaaatatat gtttgtaaac aacctttttt
    13081 tccgcattca caatattgcc cattcaattc gacaatggtg tgtccaattt ctccgatata
    13141 aggattttta gaggctccta ttttttcttt tgtgaaaaag gaagtgtaaa tacctaatcc
    13201 agcgtgtagg aaaataaagt tatcgggggt attgtgtgga ttaaaaaggt attgtcctat
    13261 agccatacaa tcgatattat tttt
//
LOCUS       DAVHSY010000047        13219 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.048, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000047 DAVHSY010000000
VERSION     DAVHSY010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13219
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.048"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..128
                     /locus_tag="VVR43_001753"
     CDS             <1..128
                     /locus_tag="VVR43_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6150072.1"
                     /translation="PLPPLALQNEFADFVALVDKSQFACEIAIKVWRNSLKFSII"
     gene            158..3508
                     /locus_tag="VVR43_001754"
     CDS             158..3508
                     /locus_tag="VVR43_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU6150073.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIEQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDNSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLEQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            3779..3934
                     /locus_tag="VVR43_001755"
     CDS             3779..3934
                     /locus_tag="VVR43_001755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150074.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKATLTRIEEI
                     FEEYKSS"
     gene            complement(4051..4521)
                     /locus_tag="VVR43_001756"
     CDS             complement(4051..4521)
                     /locus_tag="VVR43_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU6150075.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4538..6811)
                     /locus_tag="VVR43_001757"
     CDS             complement(4538..6811)
                     /locus_tag="VVR43_001757"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU6150076.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            7158..10259
                     /locus_tag="VVR43_001758"
     CDS             7158..10259
                     /locus_tag="VVR43_001758"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU6150077.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRVSFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            10342..11349
                     /gene="pfkA"
                     /locus_tag="VVR43_001759"
     CDS             10342..11349
                     /gene="pfkA"
                     /locus_tag="VVR43_001759"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU6150078.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAALVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            11408..12913
                     /gene="pyk"
                     /locus_tag="VVR43_001760"
     CDS             11408..12913
                     /gene="pyk"
                     /locus_tag="VVR43_001760"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU6150079.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAIEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT         4098 a         2250 c         2886 g         3985 t
ORIGIN      
        1 tccccctccc cccactagcc ctccaaaatg agttcgcaga ctttgtagcc ctggtcgaca
       61 aatcacaatt tgcttgtgag atagctataa aagtgtggag aaatagcttg aaatttagta
      121 taatatagct aaactatttg tttaaagtga gaaaaaaatg ggaaatttta gctttctttt
      181 aaaaaatgac gaatatgaat ctttttcaaa accttgcatt gaagctgaaa atatgattgc
      241 tacatcaact gtggctactg cctttatggc gcgtcgtgct ttggagcagg ctgtccattg
      301 gatatatagt cacgattcat atttagaagc tccctatcgt gctactctat cttctttagt
      361 atgggatgat gattttaggg atatcgtaga ttctgaactc cacaagcaga tagttctgtt
      421 gattcggtgg ggaaaccatg ctgctcatgg tggtgaaatt aaggaacgag aagcgatttt
      481 agctttacat catttgtatc agtttgttaa ttttatcgat tattgttaca gcaatgaatt
      541 tgtggagcgt tattttgatg agaagtgctt accactttca gcaaacatca aataccgaga
      601 aactccacaa tctatgataa agttacaaga cagtttacca gaactgcctg attttcatga
      661 acagatggct gctcagtccg tagaagttca agagacttat actgaaaaac gtgagactgc
      721 agcgcaacgg caagatgtgc ctttccatat tgaacaatta tctgaggcag agacaagaaa
      781 gctctttatt gatatcgatc tccgtttagc aggatggata tttgaagaaa actgtcgtgt
      841 tgagatagcc gttgatggtc tcaagcacgg ttcaggaatt ggttactgtg actatgtact
      901 ttatggtaaa aatgggaaaa ttttagcgat tgtggaggct aaaaaagcct ctgtcaatcc
      961 agaagtaggg gaagtacagg tcaaagaata tgctgaagct cttgagaaac atatcggcta
     1021 tcagccaatt tgctttatta caaatgggtt gaagcactat atacttgatg gtccgaaccg
     1081 ccgccagatt gcaggctttt actctcaaga agaattgcaa ttagtgatgg atagacgtca
     1141 tcttcaaaaa ccgcttgagg atatttctag taaaattagg gacgatattt ccgggcgtca
     1201 ctaccaaaaa catgccattg caagcgtttg tgaagctttc tctaatcatc gtagacaggc
     1261 acttttggtt atggcaactg gggcggggaa aactcgtaca gcagtttctc tagttgatat
     1321 cttatcacgt cataactggg taaaaaacgt tctcttctta gccgatagaa cttccttggt
     1381 taagcaagcc tatgattcgt ttagaaaatt actcccagat ctttccgttt gtaacttctt
     1441 agaagataaa gaaggagctc aatcaagtcg tatggtcttt tcaacttatc cgaccatgat
     1501 tggagcgatt agtggtcaag aagaagtaaa tcaacgccct tttactgttg ggcattttga
     1561 ccttatcata attgacgaat ctcaccgttc tatttatcag aaatacaagt ccatttttga
     1621 ttattttgat gcaagaattg taggcttaac agctactccg cgtcaagatt tagataaaaa
     1681 cacctatgga ttctttaatt tggagaatgg ggttccaaca tatgcatatg atttggaaga
     1741 ggctgttaaa gacggatatt tagtagccta tcattctatc gaaaccaaac tgaaactacc
     1801 tacggatggt ctacattatg atgatttgtc cgaagaagaa aaggaacatt ttgatagcaa
     1861 atttgaagac aatagctgtg aaaaagatat tgatgggagt gtatttaatt cctttatttt
     1921 caataaaagt acagtagaaa ttgttttaaa tgaactcatg acaagaggaa ttcagacagc
     1981 ctcgggtgat gaaattggta aaactattat ttttgctaaa aatcatgatc atgcggaata
     2041 tatcagaggt atttttaaca accgctatcc tgaaaaaggg agcgactatg ctcaggtgat
     2101 tgattatagt attaagcatt atcagacctt gattgatgat tttaaaatta aggagaagta
     2161 tcctcaaatt gcgatttctg tcgatatgtt agatacaggt attgatgtac cagaggttgt
     2221 taatttagtc ttcttcaaga aagtacgctc taaaactaag ttttggcaga tgattggtcg
     2281 aggaacccgt ctatgtaaag atttatttgg acctgagcag gataaggaaa acttcttggt
     2341 atttgattat ggggacaatt ttgattattt tcgtgcagat ccaagagatg gagagggtcg
     2401 tcacattgtt tcgctgactc agcgtttatt taatatcaaa gtggacttga ttcgagaact
     2461 tcagggactc caataccaag aagatcagtt tgcgagagca taccgtcagc agcttgtctc
     2521 ggaacttcaa ggtcgtatag agagcttaaa tgagttggac ttcagggttc gtatggtttt
     2581 agatacagtt tatagctata ggaaattgga aagttggcag aatctaactg ctgttacaag
     2641 tgaaaccatt caaaaaaatc tctctccgct tttatttgat gaagataaag aagatgagat
     2701 ggcgaggaga tttgatttgt ggttgcttca tattcagttg gagcaactga cagctaaatc
     2761 ttccactgtt catatttccc aagtgatgaa gacggctaga gctctttctg ctattggcaa
     2821 tatcccacag gtttttgagc aggctgaaat tatcaggaaa gtacaggagc ctgaattttg
     2881 gaaagaagtt aacttgtctg atttggaaaa aattcgtctt gctattcgag atttattaca
     2941 gtttttggat aaaacagacc gtaaacccta ctatgttaac tttgaagatc gtatactctc
     3001 cactgttcac gagaccacag catttttgca ggtcaacgat cttcggtctt acaatgaaaa
     3061 agttgagcat tatttgaaaa ctcatctgga tgaggagtcc atttctaagt tataccataa
     3121 taaaaagttg acatctgatg atatgcttgc acttgaaaaa ttgctttggg aaaaattagg
     3181 tagtaaagca gactaccaaa gtcattatga aaataaggca attccgagat tggttcgtga
     3241 gattattggc ttagatagag agtctgccaa tcgtattttt tctaaatttt tgtcggatga
     3301 gaatcttaat gccaggcaga tttcatttgt aaaattgatt gtagactaca ttgtagaaaa
     3361 tggtttttta gagacgaaag tgttaacgca agagccgttt aaatcttatg gttctgttca
     3421 actactcttc caacaccaac taccagtact tcgtaatatt gttcaaatca ttgaacttat
     3481 caataatcga gctggagaag cggcttaaat tctaaagtga ttgccatgct gagactcatt
     3541 taaaattaaa aagagtagaa atttatgcta tatatgagaa gttttattag gaagaatgtc
     3601 atcgttttcc tagaatacag tatcagttgt taagtggttg ataaatttca aagtagatac
     3661 ttgtaccacg atgtttgttg atcgagttat taacaaaaga gctactttga ttttaaagaa
     3721 atagaaaaca aaaagctgag caagaattca attgcaggag aaaatgaaat aatactcaat
     3781 gaaaatcaaa gagcaaacta ggaaactagc tgcaggctgc tcaaaacact gttttgaggt
     3841 tgtagatgaa actgacgaag tcagtaacca tacctacggc aaggcgacgt tgacgcggat
     3901 tgaagagatt ttcgaagagt ataaatcttc ctaggataaa gcaaaacgca tagtatcaag
     3961 ggttttcaac acttgatact atgcgttttc tgatgttaaa gactttctac caggtttttt
     4021 aaaagcataa ttgttagttg tagtcattta ttattcttca aagaaaaatg gtggggcgaa
     4081 ttttttcagt tcttcaaagc acttttgagc agtatctgca tcttcacaga tgataagaca
     4141 gacatcatta ccacaaaggg tagcgatagc gtcagggaag ctcaaagtat caatgataga
     4201 accaaaggat tgagccagtc caggaagggt ttttagtagg acttggtgtt gaactgggcg
     4261 catccagaca agggcgtctt ccatgtagag ttcgagacgt ttttcccatt ttgagatgga
     4321 accattgtta agaacataat aagcgctatc ttcttcgcgg acttttgata ggttcatatt
     4381 tttgatgtcg cgtgagaggg ttgcctgggt tacttgaatg tcgttcttag caagaagggc
     4441 ttgcaactca gcctgtgtat gaatcttgtt ttttgtgata agagcgcgta taagttggtg
     4501 gcggtgttct gatttattca taataatgta actcctttta gcaaggtaag gtaagcatgg
     4561 actgagcgag gtcgacagtc aagtggtagt ctgtattgtc acggatggtg atttcaaagt
     4621 cagtagtata gaggactaaa cggagagtgt ctccttcttt tagcttgtaa atagttggct
     4681 gcagttcaaa ttgaacgtcc atccattcat ctgcagtaat atcctctact aacagtaaat
     4741 catttctatt ttgtaaatta aggtaacctt ttgtcacgac tcgttgtgcc tctggtctaa
     4801 atggcaattc acagagattt tccaacatgt gatagcgacc gttgtcaatg gttctagcac
     4861 ttaaaatagc tggataaggt tgtaggtatt tcttttgccc aaattctagc agttgggcag
     4921 ataagagccc cttgtttgta ctggatttga tacgaagatt gagctgagcg cgaccgttta
     4981 ggtggagatc tttagtcaca ggaaggttaa tagtaatctg attagctttc ccttgataga
     5041 gctctgtatt gaaggtttgg tatgtcttac catagcgctc aaaatcctta tctgggtact
     5101 ggttttgaat agcttgctct tcttgaccaa gtgagaaggt ttcacagttt tcttgcccac
     5161 cgaagttatc aagtgataac caagtctgtg gagctgtatt gtcctgccag ataacagtag
     5221 gaagttgaaa gtctgtttcc tgtcctagta atttcttggt caataaggca tttatggact
     5281 cacggaagtc aattgattgc caattgttca tgtaaacatg ggcaccatta tggaaaaaga
     5341 gatgcttgtg tatatgagta ggaagagcat ggaacatctg gtaaacatga agtggtttga
     5401 cattccaatc ctgagaacca tgagtaaaga caacctctgc ctttacttta tgggcattga
     5461 gcagataatt gcggtcatgc caaaactgat tgtagtcccc agtttttcgg tctagctgag
     5521 ctttcacttt ttctaagtca gcttggtgag cttcattgcc acggatatag tcgccagcta
     5581 agagattacg agaataggtt aactcagcaa gggagtcaaa gtcctcacct ggataaccac
     5641 ctgggctagt caccagaccg ttttcacggt agtagttgta ccatgatgaa attcctgcct
     5701 cggcaatgat aacttctaaa ccatcgactc ctgtagtcgc aagaccattg gacatggtac
     5761 ctagatagga aagtcctgtt gtagcaactt ttccgtttga ccaatcagcc ttgacttgac
     5821 gctggcgcgt gtgatcagta aaggcacggc aacgaccgtt aagccaatcg atgacgtttt
     5881 tataagcctc gatttgctgg tagtctccat tagtcatgaa acctgtcgag tctttggtac
     5941 caacacctga gacatagaga ttggcaaagc ctctcggaag gaagtagtcg tttagtgtat
     6001 agctagagtt gatgtgagtt agcttttcct cagcctctgc tataagctca gctttacctt
     6061 ggggttggac gagatttagt tgaggtttct ctagctcaat cttgtgagga agcttaacct
     6121 caagctcgcc ctccatcttg tagagagcct tgtcactagc cttgtcattg gttccctgat
     6181 gataagggct ggctgtcatg atggcaggga tttttccatc aaaacgaggg cgaataatgc
     6241 taacctttac taggtctgat agcccttttt ggtcagtatc gacacgagac tcaacgtaaa
     6301 cgacttcacg aatgacatcc tggttagaaa aagtagccaa actcttgccg ttaaagtagt
     6361 ggtagtcatt atcctccgga ataagaccat cactaacaag ttggtcgata agagtatttc
     6421 cttttttggt gcgagtattg agtaactgat agagattttc aatcaagtca ccatatataa
     6481 tgggaaatcc agtttcttta cgaaaaacgt cactatcttc gaagtcaacc aaataagaaa
     6541 agcctaaaag ttgaaaagca acagtataaa aaatatctgc tgtcagttca tcttctgatt
     6601 gaaaaaatgt cagcaggtct gtttttttat cagctgctag gatagaaagt gggtagttgg
     6661 tgtcttgata agtgaaaaag aaacgacgta aaaaggtttc aagtgagtct ttgtgattgg
     6721 ctgtattttg taaatcaaag ccacattttt ttagttcaga taagacattt tcttttggaa
     6781 aattgatata actatattga ttaaaacgca tagaacctcc atatagaatg acagttaagg
     6841 ttattatatc aaaaaaaaag cagaaaggga attgttaact tcaaaaggaa ataatccaat
     6901 aaaaatgaat aaagtactaa attcaatata gagaacagag taacaataag aataaataga
     6961 tagggtataa aagttctagg agatttatat tatatgcttt ctatttttat atacaatata
     7021 gtataaatat aaaaatgatg acaaaaatac aaatgaatag aaaataaatt agtaagctga
     7081 tgaaattttt ctcaagagaa gccatttata ggtgaaaatg gtataatata gtgagaagga
     7141 tagaggagaa gtgtaaattg atcgcacaac tagatacaaa aacagtctat agttttatgg
     7201 aaagcgtcat ttcgatcgaa aagtatgtga gagcagctaa agaatacggc tacactcatt
     7261 tggctatgat ggatattgac aatctttatg gcgctttcga ctttctagag attacaaaaa
     7321 aatacggcat tcatcctttg ctagggcttg aaatgacagt gtttgtagat gatcaggaag
     7381 tgaatttgcg ctttttagct ctatctagtg tgggctatca gcagttgatg aagctttcga
     7441 cagccaagat gcagggggag aaaacttggt cagtcctgtc ccagtacctg gaggatatcg
     7501 cggtcattgt gccttatttt gatagagttg agtcgttaga actaggctgt gattactata
     7561 taggggttta tccagaaaca ctagcaagcg aatttcatca tcctatctta cctctttatc
     7621 gggtcaacgc ttttgaaagc agggatagag aagttcttca agttttaaca gcgattaaag
     7681 aaaatctacc gctcagagaa gttcccttgc gttcgagaca agatgtcttt atatcagcaa
     7741 gttctttaga gaaactattc caagagcgtt ttccgcaagc tttggacaat ttagaaaagc
     7801 ttatttcagg catttcttac gacttggata ctagtctgaa actgcctcgt tttaatccag
     7861 ctagaccagc agtagaggag ttgagagagc gtgctgaact ggggcttgtt cagaaggggt
     7921 tgactagtaa agaatatcaa gatagactag accaagaatt gtctgttatt catgatatgg
     7981 gctttgatga ttatttcttg gttgtttggg atttgttgcg ttttggacga tcgaatggct
     8041 attatatggg aatgggaagg ggttctgcag taggcagttt ggtttcttat gccttagaca
     8101 tcacggggat tgacccagta gagaaaaatc tgatttttga acgctttctt aatcgtgaac
     8161 gctataccat gcctgatatt gatattgata tcccagatat ttatcgtcca gattttatca
     8221 gatatgttgg taataaatat ggtagtaaac atgcggcaca aatcgttact ttttcaacct
     8281 ttggagccaa gcaagctctt cgagatgtct tgaaacgctt tggtgtgcca gagtatgaat
     8341 tatctgcaat tactaagaaa atcagttttc gtgacaatct taagtcggcc tatgagggca
     8401 atctccagtt tcgtcagcaa atcaatagta agttagaata ccaaaaagct tttgagattg
     8461 cttgcaagat agagggctat ccaagacaaa cctctgtcca tgcggctggt gttgtaatta
     8521 gtgaccaaga tttaaccaac tatattcctc taaagtatgg tgatgaaatt ccactgactc
     8581 agtatgatgc tcatggagtt gaggctagcg gacttttgaa gatggacttt ctgggactac
     8641 gaaatttgac ctttgtccag aagatgcaag agttgcttgc tgaaatagaa ggtattcacc
     8701 ttaaaattga agaaatagat ttggaagaca aagaaacgtt agatttattt gcctctggaa
     8761 atacaaaagg tatctttcaa tttgagcaac caggtgccat tcgtctgctt aagcgtgtgc
     8821 aaccagtctg ttttgaagat gtcgtcgcga ctacttctct aaatcgaccg ggtgctagtg
     8881 actatatcaa taattttgtg gcaagaaagc atgggcagga agaagtgact gttctggatc
     8941 cagtactgga ggatattttg gctccaacct acggcataat gctctatcag gagcaggtta
     9001 tgcaggttgc ccagcgattt gccggattta gtcttgggaa agccgatatt ttgcgtcggg
     9061 ctatggggaa aaaggatgcc tctgccatgc atgagatgag ggtttccttt attcaaggtt
     9121 cattagaagc tggtcatact gtggaaaaag cagagcaggt ctttgatgtt atggagaagt
     9181 ttgcaggtta tggttttaac aggtcacacg cctatgccta ctcagccttg gccttccagt
     9241 tggcttattt taaaacacat tatccagcca ttttttatca ggtcatgtta aattcttcca
     9301 acagtgatta cttaatagat gcacttgaag caggttttga agtagcctct ctatccatca
     9361 acaccattcc ctatcacgat aaaattgcca acaaggccat ctatctaggt ttgaaatcca
     9421 ttaaaggagt cagtaatgat ttagctctct ggattattga aaatagacct tattctaaca
     9481 ttgaagattt tatagctaaa ttacctgaga attatctgaa acttcctctg ctagaacctt
     9541 tggtaaaagt tggtcttttc gattcatttg aaaaaaatcg tcaaaaagta tttaataatt
     9601 tagctaatct atttgaattt gtgaaagagt tgggaagttt gtttggagat gctatttata
     9661 gttggcagga atcggaagat tggacggaac aagaaaaatt ttatatggaa caagagcttt
     9721 tagggatagg tgtcagcaaa catccactac aagctattgc aagtaaggct atttacccga
     9781 ttaccccaat cggaaatttg tcagaaaata gctatgctat tatcttggtt gaagttcaga
     9841 aaataaaagt gattcgtacc aaaaagggtg aaaatatggc cttcttacag gcagatgata
     9901 gtaagaaaaa attggatgtc actctctttt cagacttata tcgtcaggtt ggacaggaaa
     9961 taaaagaggg agccttctac tatgtaaaag gaaaaataca atcacgtgat ggccgtctgc
    10021 aaatgattgc acaagaaata agagaagcag ttgctgaacg cttttggata caggtgaaaa
    10081 atcatgaatc ggatcaagaa atttcacgca ttttagaaca atttaaaggc ccaatcccag
    10141 tcatcatccg gtatgaagag gaacagaaaa ccatcgtttc tccccatcat tttgtagcta
    10201 aatccaatga attagaggag aaattgaatg aaatcgttat gaaaacgatt tatcgctaaa
    10261 aatacggaaa atagaagaat tttaaaatca aatgtgatat aatcaagaag aatgttaaaa
    10321 gaaaaaggag cataaaccaa tatgaaacgt attgctgttt tgactagtgg cggagacgca
    10381 cctggtatga acgctgccat ccgtgcagtt gttcgtcaag caatttcaga aggaatggaa
    10441 gtgtttggta tctatgacgg atatgctggt atggttgccg gtgaaattca tcccctagat
    10501 gcagctttag taggggacat catttctcgt ggtggtactt ttcttcactc agctcgttat
    10561 ccagagttcg ctcaacttga agggcaactt aaagggattg agcaattgaa aaaacacgga
    10621 attgaaggtg tagttgttat cggtggtgac ggatcttacc acggcgctat gcgtttgact
    10681 gaacatggct tcccagctat tggtcttcca ggtacaatcg ataacgatat cgttggtact
    10741 gactttacaa tcggttttga cacagcggtt actactgcca tggacgctat cgataagatt
    10801 cgtgatacat catcaagtca ccgtcgtact tttgtaatcg aagttatggg acgtaacgct
    10861 ggtgatatcg ctctttgggc tggtattgca actggtgctg atgaaatcat catccctgaa
    10921 gcaggcttca agatggaaga tatcgtagca agcatcaaag ctggttatga atgtggtaaa
    10981 aaacacaata tcatcgtctt agctgaaggt gtgatgtcag cggctgaatt tggtcaaaaa
    11041 cttaaagaag ctggagatac aagcgacctt cgtgtaacag aacttggaca tattcaacgt
    11101 ggtggttctc caactgcgcg tgaccgtgtt ttggcgtcac gtatgggtgc acatgctgtt
    11161 aaacttctta aagaaggtat cggtggtgtt gcggttggta ttcgtaacga aaaaatggtt
    11221 gaaaatccaa ttcttggtac tgcagaagaa ggggcattgt ttagccttac tgcagaaggt
    11281 aagattgtgg ttaacaaccc gcacaaagcc gatattgagc tatctagctt gaataagagc
    11341 ttgtcataat ttacaattta gttaataaga ccaaaaaggt catatatata aaggagtcac
    11401 aaaaatcatg aacaaacgtg taaagatcgt tgcaactttg ggtcctgcgg tagaaatccg
    11461 tggtggtaaa aaattcggtg aggatggata ctggggtgaa aaacttgatg ttgaagcttc
    11521 agctaaaaac attgctaaat tgattgaagc tggtgctaac acattccgat tcaacttctc
    11581 acacggcgac caccaagaac aaggtgagcg tatggcaact gttaaacttg cggaaaaaat
    11641 tgcaggtaaa aaagttggtt tccttcttga tacaaaagga cctgaaatcc gtacagaatt
    11701 gttcgaaggt gaagctaaag aatattcata caaaactggt gaaaaaattc gtgttgcaac
    11761 taaacaagga atcaaatcaa ctcgtgaagt gattgcgttg aacgttgctg gtgctcttga
    11821 tatctatgat gatgttgaag ttggtcgtca agttttggtt gacgatggta aacttggtct
    11881 tcgtgtggtt gctaaagatg atgcaactcg tgaatttgaa gttgaagttg aaaacgatgg
    11941 tatcatcgct aaacaaaaag gtgtgaacat ccctaacact aaaattcctt tcccagctct
    12001 tgctgaacgc gataacgacg atatccgttt cggtcttgaa caaggtatca acttcatcgc
    12061 aatttcattc gtacgtactg caaaagatgt gaacgaagtt cgtgcaatct gtgaagaaac
    12121 tggaaacgga catgttcaat tgttcgctaa aatcgaaaac caacaaggta tcgataactt
    12181 agacgaaatc atcgaagcag ctgatggtat tatgattgct cgtggtgata tgggtatcga
    12241 agtaccgttc gaaatggttc cagtttatca aaaaatgatt atcaagaaag tcaatgctgc
    12301 aggtaaagtt gttatcactg caacaaacat gcttgaaaca atgactgaaa aaccacgtgc
    12361 aactcgttca gaagtatcag acgtattcaa cgctgttatc gacggaactg acgctacaat
    12421 gctgtcaggc gagtctgcaa acggtaaata cccactcgag tcagtaacta caatggctac
    12481 aatcgacaag aacgctcaag ctcttcttaa tgaatacgga cgtcttgatt cagattcatt
    12541 tgagcgtaac tctaagacag aagtaatggc ttctgctgtt aaagatgcta ctaactcaat
    12601 ggatatcaaa ttggttgtaa ctcttactaa gacaggtcat actgcacgtt tgatttctaa
    12661 ataccgtcca aatgctgaca tcttagcatt gacatttgac gaattgacag aacgtggctt
    12721 gatgttgaac tggggtgtta tcccaatgtt gacagatgct ccatcttcaa ctgacgatat
    12781 gttcgaaatc gctgaacgta aagcgataga agcaggtctc gttgagtcag gcgatgatat
    12841 cgttatcgtt gctggtgtgc cagtaggaga agctgttcgc acaaacacaa tgcgtatccg
    12901 cacagtacgt taagaaaaat ataaaaacct atcatatcca gctttagagc ttgtgtgata
    12961 ggttttttgt atagagggta acaaagaggc aaaactttca taatcgattg aaataagata
    13021 tgcacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagcaa tcgtaatgta
    13081 cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta aaacctccaa
    13141 agtagcttgc tccattcttt tacttacgtg agtgtagatg ttatttactg ttttagcgtt
    13201 tttgtgttcc actctaacc
//
LOCUS       DAVHSY010000048        11421 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.049, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000048 DAVHSY010000000
VERSION     DAVHSY010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11421
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.049"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(147..2144)
                     /gene="metG"
                     /locus_tag="VVR43_001761"
     CDS             complement(147..2144)
                     /gene="metG"
                     /locus_tag="VVR43_001761"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU6150080.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLDKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2268..3527)
                     /locus_tag="VVR43_001762"
     CDS             complement(2268..3527)
                     /locus_tag="VVR43_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6150081.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3529..4230)
                     /locus_tag="VVR43_001763"
     CDS             complement(3529..4230)
                     /locus_tag="VVR43_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6150082.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4214..5413)
                     /locus_tag="VVR43_001764"
     CDS             complement(4214..5413)
                     /locus_tag="VVR43_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU6150083.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPATGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KTDEATN"
     gene            5699..7045
                     /gene="gor"
                     /locus_tag="VVR43_001765"
     CDS             5699..7045
                     /gene="gor"
                     /locus_tag="VVR43_001765"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU6150084.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            7242..7778
                     /locus_tag="VVR43_001766"
     CDS             7242..7778
                     /locus_tag="VVR43_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU6150085.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            7829..7915
                     /locus_tag="VVR43_001767"
                     /pseudo
     CDS             7829..7915
                     /locus_tag="VVR43_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(7984..8199)
                     /locus_tag="VVR43_001768"
     CDS             complement(7984..8199)
                     /locus_tag="VVR43_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU6150086.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            8297..8617
                     /locus_tag="VVR43_001769"
     CDS             8297..8617
                     /locus_tag="VVR43_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150087.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(8647..8985)
                     /locus_tag="VVR43_001770"
     CDS             complement(8647..8985)
                     /locus_tag="VVR43_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150088.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(8997..9716)
                     /gene="trmD"
                     /locus_tag="VVR43_001771"
     CDS             complement(8997..9716)
                     /gene="trmD"
                     /locus_tag="VVR43_001771"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU6150089.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(9706..10224)
                     /gene="rimM"
                     /locus_tag="VVR43_001772"
     CDS             complement(9706..10224)
                     /gene="rimM"
                     /locus_tag="VVR43_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU6150090.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(10255..11043)
                     /locus_tag="VVR43_001773"
     CDS             complement(10255..11043)
                     /locus_tag="VVR43_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6150091.1"
                     /translation="MKRFEVSTEIGSLSVAYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEALEELGISEYILCVHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(11147..11390)
                     /locus_tag="VVR43_001774"
                     /pseudo
     CDS             complement(11147..11390)
                     /locus_tag="VVR43_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
BASE COUNT         3275 a         2526 c         2080 g         3540 t
ORIGIN      
        1 catgttttga gctgacttcg tcagttctat ctacaacctc aaaacagtgt tttgagcaac
       61 ctgcggctag cttcctagtt tgctctttga ttttcattga gtataaataa aaaaacagaa
      121 ctagcctgaa ctagtcctgt ctacttttac ccaatcacac ttccatttgg tacagctgga
      181 tcaactgtga gaagggttaa tttaccatca tgttcagctg agagaatcat accctggctg
      241 acatattttt tcatcatttt acgtggtttg aggttagcaa cgatttgaac tttcttgccg
      301 accaattctt gttcatttgg atagtatttt gcaattcctg aaagaatctg acgatcttct
      361 ccatcaccag catccaagcg gaattgaagc aacttatctg aaccttctac tttagacact
      421 tctttgactt ctgccacacg gatttcaacc ttgtcaaagt cttcaaactt gatttcatcc
      481 ttgtttagtt tgagctcaac ttcgtccgga ttccattctt tttcgactgc tggtttattg
      541 ccttccattt gttccttgat ataggcgatt tcttcttcca tatttagacg tggaaagata
      601 ggtgttcctt tggcaactac agtcacatct gctgggaagt cagccaaact caagttttca
      661 agactagaaa cttcttccaa accaagttga gtcaaaactg cacgactagt ttccatcata
      721 aatggttcaa tcaagtgagc aactacacga atgctggctg ccaagtggct catgacactt
      781 gccaattggt cacgaagagc ttcatccttg tccaagaccc atggtgcagt ctcatcgatg
      841 tatttattgg tacgagagat cagagtccag actgcttcaa gcgcacgtgg atagtcaact
      901 gcttccatgt gtgtatggaa gtctgcgatt gattgttctg caacctcagc aagaacatga
      961 tcaaattcag tcacaccttc tacataggca gggatttgtc catcaaagta cttattaatc
     1021 atggaaaccg tacggttaag gaggttccca aggtcattag ccaattcata gttgatacgg
     1081 ccgacatagt cttcaggagt aaaggttccg tctgaaccaa ctggaaggtt acgcatgagg
     1141 tagtaacgaa gtggatctag tccataacgc tctaccaaca tttcagggta aacgacattc
     1201 ccttttgact tagacatttt tccgtctttc atgacaaacc aaccatgggc aatcaaacga
     1261 tcaggtaatt taacatccaa catcataaga aggattggcc agtagataga gtggaagcga
     1321 aggatatctt ttcctaccat atggaagact gttccattcc agaacttgtc aaagttacca
     1381 tgttcgtctt gagcgtagcc aagagctgtc gcatagttaa gaagggcatc aatccaaacg
     1441 tagacaacgt gttttggatt tgatgggaca ggcactcccc atgtaaaggt tgtacgagat
     1501 accgccaaat cttccaaacc tggctcgatg aagttgcgta gcatttcatt aaggcgacca
     1561 tctggcgtga taaattcagg atgagctttg aaaaattcga ccaaacggtc ttggtatttg
     1621 ctaaggcgaa ggaagtatga ttcttcagaa acccattcaa cctcatgacc tgatggagca
     1681 ataccaccag tcacatttcc agcttcatca cggaaaactt ctgccagctg gctttctgta
     1741 aagaattctt cgtctgatac tgaataccaa ccagagtatt cacccaagta gatatcatct
     1801 tgagcaagta agcgttcaaa gacctgtgca acaacttttt catggtagtc atcagttgta
     1861 cggataaatt tatcgtatga gatatctagt aattgccaga gttctttaac tccaaccgcc
     1921 attccatcaa cataggcttg aggtgtaata ccagcttctt ccgctttctg ctggattttc
     1981 tgaccatgtt catcaagacc tgtcagataa aatacatcgt agcccatcag gcgtttgtaa
     2041 cgtgctagga catcacatgc gatagttgtg taggcagaac cgatatgaag tttcccagat
     2101 ggatagtaaa tcggcgttgt aatataaaaa ttcttttcag acataatttt tcctttccag
     2161 gcaaatgaaa cctgtttttc taacacttca ttatatcaca tttttaatga atttcgatag
     2221 ggaaatccat acaaaaacaa gatagacgag tgtccatctt gttgatctca ttcataacga
     2281 agggcttcaa ttggatcaag tttcgatgcc ttgttggctg gcaagactcc aaaaatcata
     2341 ccaacactag ccgaaactgc aagactaaat agggcaactg ggattgatac tccaacttct
     2401 ataccttcta ttaaaccttg cagtaacaaa cctgctaagg cagttaaacc acttgcaatt
     2461 gtcaagccaa ttaagccacc taacaaggtc aaaatcatgg attcaatcaa aaactgaatt
     2521 aaaatattgg cacgtgttgc gcccaaagcc ttacgaagac caatctcacg agtgcgctct
     2581 gtcaccgaaa ccagcatgat gttcatgaca ccagttcctc caacaaagag agaaatccct
     2641 gcgatggaac taataatcgt cgtcataaaa ctaaacgatt gttgaatttc tgcaaataca
     2701 acggactcat ctgccacctg gtattctccc tgttgtaagc ctgcaagctc tgtcattttt
     2761 cgtgccaatt ctggacccag agttggggtt aaactggtat cattcactcg aaagacaata
     2821 ttagctattt catctacatt aaaattcgca gcaagggaga tattggtagt aataggcaag
     2881 ccaccaaacc catatatttt tgatctttta gcctccggac tagtataaac cccaatgacc
     2941 cggtaactaa atccattgac ttctacaacc ttgttaatag cctcttgagg agattcaaat
     3001 aaactaatgg acaattcctc atctagcaaa atgacacttg caaactcttt gaaatcttgc
     3061 tctctcagac tacgacctgc aataatttca ttcttaacag cgtccatgta agttctgttt
     3121 ccacctgtca aattagcatt ctcaaccttt ttatcttgat aggtcaagat ggcattcgtt
     3181 gaattggtta catagtaact atccactccc ttcagtttag ctgcctcttg aacccaggat
     3241 tcttgcggtt ttggcggttc aacaggaact tcctcttcct ttccagaaac cgtaaaagct
     3301 gattgtttct gagtaaaaga cccatcttta ctttttttag gagagaaaaa gacgctaata
     3361 tttttctgag atttagtcat atctttattg acttgacgag atagggaatc acccaaagcc
     3421 ataatcacaa caactgatga aacaccgata ataatcccaa tcatagtaag caaagaacgc
     3481 atcttgtgag ccatgataga tgaaaaggca aatttcagat tctgcatctt agttttcctc
     3541 ctttcctaac tgagcactgt cagacgaaat gaccccatcc cgaatgacaa tctgacgttt
     3601 ggcataggca gcaatctcag gctcatgcgt taccatgata atggtttttc cttctttatt
     3661 caaatcaacc aataattgca taatttggtt acctgttttg gtatccaagg ctcctgtcgg
     3721 ttcatccgct aggataatag aaggattgtt taccaaggca cgcgcaatgg ctacacgttg
     3781 cttttgacca ccagataatt ctgaaggtaa atggtgacta cgttctgtca attcaacctt
     3841 gtctaaatat tcctcagcca acttgcgacg ttttgaagac gaaactcctg cgtaaatcaa
     3901 gggcaattct acattttgca gagcattgag cttcgataga agaaagaact gctgaaagac
     3961 aaaaccgatt tgttggttac ggaccttagc cagttgtttt tcaccaagcc cagccacttc
     4021 ttgaccttca agataatatt ctccactggt tggtgtatcc aacatgccaa tcgtattcat
     4081 cagagtggac ttaccagacc cagatggtcc catgatggct acaaattcac cctcattcac
     4141 ttctagattg atatttttga gaacctgcaa ttcttggtca ccattacggt agcttctgaa
     4201 gatatttttt agactaatta gttgcttcat cagtcttcac ctcttttcct tcttccaagg
     4261 aagatgttgg attactgatg accttagcac cattcgttaa accagaagtg atttcttgat
     4321 tttctgcgtc agcatttccc aatgaaacct caactttttt agccttttgt tgttcatcca
     4381 caatccagac ataattttta ctatcatcca ttactagact gctaacagga acaagaatag
     4441 ccttagtttt gcttttaacc tcaatgttga cagaaaaacc ctgtttcaaa tcaccaacct
     4501 cgcctgtcac atcaatagta taagggtatt tagaacctgt attattcccg gttgctggac
     4561 tagctgcttc accattgttt ttaggatagt cagaaatata gcttaatttc ccagtccatt
     4621 ttttatcagg atacacttta gaagtaaagc ttacttcttg acctacagaa aggttggcta
     4681 gattgtactc agacaattct cccttgactt gtaaattttc attgctgaca atatgaacca
     4741 taacttgact cgcccctgtt ggagatttag aaacattgct attgacttcg actacagttc
     4801 cctctagggt actgagaaca gttgttgcat ccaattgact ttgagccttg cttaattgcg
     4861 ctgcagcatc tgcacgcgca tcacgggcat cacccaattg agcatcaata gaagcaacag
     4921 aatttccagc cactggagtt gggctttgca ccgttgcatc ttctcctcct actggcgctg
     4981 gtaactgtgg agcctgagct gaagcggctt catttcgtgc ttgattgagt tcattgatat
     5041 gacgatctgc cttagctact gctcgactag ctgaatcata ggccgcctgc gcttctgaac
     5101 tactgtactt gactaaagcc tgcccttcgc tgaccttatc gcccacagaa acaaggattt
     5161 catctaaatc acccttacta gcatcaaaat aaacatattg ttcatttttt gctgttactg
     5221 tccctgacaa taaaacagag gatgccacgc ttccttcctt ggcaacaaca agatgagtag
     5281 gctcatcttt tacagcagtc tgagaaggtt gtctaaaaag taaaatcccc ccggcaccca
     5341 atacaactac actcgcagca ccgattgctg catacagttg ccacttttta gctttaccat
     5401 tctttttctt cataatgaaa ctccttttct tttttacaat actttgctat tataccaaat
     5461 ttccctccag caaacaatgc agttcagatg gaaataatgg cagttcagga ttaaacaatc
     5521 gttcggaatt ttgcttttct attgtactag atatataata cactatcttg acttatttgg
     5581 caagcttttt tgcaattttt tgtgcgtagc agatttttgc aatcaaatca aaaaaagaat
     5641 aaaatataac tatcaaaaaa gacactctac tatttaaaag attacaaagg agttttcaat
     5701 gagagaatat gatatcattg ctatcggtgg aggtagcgga ggaatcgcta ccatgaaccg
     5761 tgctggtgaa catggagcca aagcagccgt tattgaggaa aagaaattag gtggaacctg
     5821 tgtcaacgtc ggttgtgttc ctaaaaaaat catgtggtac ggggcgcaaa tcgctgagac
     5881 tttccatcaa tttggagaag actacggctt taagactact gatcttaact ttgactttgc
     5941 aaccctacgt cgcaatcgtg aagcctacat tgatcgcgct cgttcttctt atgatggtag
     6001 ttttaaacgc aacggtgtag acttgattga aggtcatgct gaatttgtag attctcatac
     6061 tgtaagcgta aatggtgaac tgattcgtgc taaacatatc gtgattgcta caggtgccca
     6121 tccaagtatt cctaatattc ctggtgctga gctaggtggc tcttctgatg atgtatttgc
     6181 ctgggaagaa cttccagagt caattgccat tctaggcgct ggttatatcg ccgttgaatt
     6241 agctggcgta ctccacactt ttggtgtcaa gacagatctc tttgttcgcc gcgatcgtcc
     6301 tttacgtggt tttgattcct acatcgttga aggtttggtc aaggaaatgg aaagaacaaa
     6361 cttaccactt cacactcaca aagtccctgt caagttagaa aaaactactg acggcattac
     6421 cattcatttc gaagatggta ctagtcacac agctagccaa gttatctggg ctacaggtcg
     6481 ccgtccaaac gttaagggct tgcaacttga aaaagctgga gtgactctga acgaacgtgg
     6541 ctttatccaa gtggatgaat accaaaatac tgttgttgag ggaatctatg ctctaggtga
     6601 tgtaacgggc gagaaagaac tgactccagt tgcaatcaag gccggacgta ccctatctga
     6661 acgtctcttt aacggaaaaa ctactgcaaa aatggattac tcaactattc caactgttgt
     6721 cttttcacac cctgctatcg gaactgttgg tttgacagaa gagcaagcta ttaaagaata
     6781 cggtcaagac caaatcaagg tttataaatc aagctttgca tctatgtact ctgcttgcac
     6841 tcgcaaccgt caagaatccc gtttcaaact cataacagct ggttcagaag aaaaagttgt
     6901 cggacttcat ggaattggct acggcgttga tgaaatgatt cagggatttg ccgttgctat
     6961 caaaatggga gcaaccaagg ctgactttga tgcaactgtg gcaattcacc caactgcatc
     7021 tgaagaattt gtaaccatgc gttaatcgaa acaaaagaag ctgatataaa tatgtctgct
     7081 tcttttttaa tgattttcga atcaacaaaa aaattatcca acttgactag tcacgaaaat
     7141 cggctgttac agtttttgtt accttgtttt taaaaaatgg ttgacatcga ctcctatatg
     7201 agtataatag ttactataca ttagaaaaga ggttaactat tttgaaaaaa gctcacgttt
     7261 atgctatccc tgctattggg gctgctctca ttgctgcttt ggcacaaatc agtcttccaa
     7321 ttggacctgt tcccttcact ctgcaaaact ttgcaatcgg cttgattgct actgtcttta
     7381 gaccgagaga ggctgtactt tctgctggac tctatcttct tctaggtgct atcggtcttc
     7441 ctgtctttgc aggaggtgga gctggttttc aggctttagt tggccctact gcaggctatc
     7501 tttggtttta tctcgtttac tctggactta cttcctctct aaccaacagc aagagtggtg
     7561 ttgttaagat ttttcttgca aacctcttgg gtgatgccct tgtctttgtc ggcgggattc
     7621 tcagcttgca tttcctagct ggaatggcat ttgaaaaagc tcttgctgtg ggggttcttc
     7681 cctttatcat tccagacctt ggcaaacttc tggctattag ttttattagc cgtcccctac
     7741 ttcaacgcct taaaaatcag gcttacttta ctaactaaaa aaggatatcg agttatcatg
     7801 actcaatatc cttttctttt attttgaaaa cttatactca atgaaaatca aagagcaaac
     7861 taggaagcta gccgcaggct gctcaaaaca ctgttttgag gttgtggatg aaactgacga
     7921 agtcagtaac catacatacg gcaaggcaaa gctgacgcgg tttgaagaga ttttcgaaga
     7981 gtattagttg cctttaaagg catccaccat cgtttgaaat tcttcatttg agagagtaat
     8041 ccctttgccc attttagtat ggtctggact ccaagcacga atatcaaact ttgcaggggc
     8101 accattaaag ctcacacggt taatttcctt ggtccaacct ttttcgtttt cagaaagagt
     8161 caacaagtgc tcttcgattt caaatgtaaa ttctgccatt ttcttctcct tttttagttt
     8221 cattagttta ttcgtaaaat cttgtagatt ttaggaaaat tttatataat attgatataa
     8281 aagaagggag gccaatatga gacataaatt ccagcaagtt ctaaataaaa tacatgattt
     8341 tttaaatgga tatgaccaac ctgaccagac tgaaaccaac tcccttacag ccactattga
     8401 agaggctatc cagaaacaaa ccgctgttca ccttatcttg tctgagacaa gctttacagg
     8461 tgacatcatc aaatatgatc agcaaggcca gcaaattatc gtgaaaaatt tttccaaaaa
     8521 tgtgagccgg attatccgta taagcgatat tcaacgcctg cgatttgtcc cctcaactgt
     8581 ccaaacagcc caaaaaaata gatttaagaa agagtgagat gtagttgctt catcccactc
     8641 tttttcttag cgaatttgtt caaaatgtaa atgaactgca atatgatctc cataaccact
     8701 tctttccaag tcacgttgta aacgatagga aatgtagtgt tctgcaatgg taatgtaacc
     8761 tgcgcccaat aaacgatgtt caaccataga ttgaatcata ctgatagtcg cacgttccac
     8821 cttggcttct tgtaaatcca aaactacctt cttagtgact tgagcaagat tttgacgcaa
     8881 atcatctgtc aaaacataaa cagtttgggc tgccttcaag atggcttggt aaatcttatc
     8941 tggattaaat tcagcaattt cgccattacg tttgattact tgcataggtt tctcctttat
     9001 tctttgtttt ctttgatttc tgccagcatt ttttcttctt ctactgtcag ttgataatgt
     9061 tcaagtaaat ctggtctgcg ctcgtaggtt ttctttaaac tctcgtacaa tcgccactga
     9121 cgaatctttt catggtggcc actcatcaat acatctggca cgaccatgcc tcgataatca
     9181 tagggacgtg tgtactgagg atattctaaa agacctgaag aaaaactatc atcttggtgg
     9241 ctagactcct tgccaatcac ttctggaatc aggcgaactg tagcatcaat catggtcata
     9301 gctgccaatt ctccaccagt gaggacatag tcgcctaggg aaatctcatc tgttaccaag
     9361 gtcttaatgc gctcatcata accctcatag tgcccacaga taaagattag ctcttcctct
     9421 tgagccaaat cttcagcata agcctgatca aactgctttc cagcaggatc gaggagaata
     9481 acgcgcggat ttttcttttc aatagcatca aaggaatcga aaataggttg tgctctgagc
     9541 aacatgccct gaccgcctcc gtagggctca tcatctacat gacgggcctt ttcagcattt
     9601 tctcgaaaat tatgatactg gatatccaag agcccttttt ctcgagcctt tccaacgatt
     9661 gagtgctcca gtggagaaaa catctctgga aagagggtta aaatatcaat cttcatcgtc
     9721 taacccttct aagatttcca catcgacccg tttatttgga atatcaacat tgagaaccac
     9781 tggtgggata taaggtaaaa gcaaatcacg tttgcctttt cgtttgacca cccagacatc
     9841 attagcacct ggttgcagga tttccttgat ggttccaacc aagctatcac cctcatagac
     9901 ttccaaaccg ataatctcgt gatagtaaaa ttcaccatcg tctaggtcat tcaaatcttc
     9961 ctcagcgacc ttgagactgt atcccttgta cttttcgata gtattgatat ggtacatatc
    10021 tttgaattta ataatgtcaa agttcttctg tttacggtgg ctagcgatgg tcactgtttg
    10081 gacaaactga tctttttcat caaacaaagc cagctcagct ccttttttaa accgttcttc
    10141 tgcaaaatcc gtcacagaca agactcgcat ctcaccctgt aatccctgcg tattaacgat
    10201 tttcccaaca ttaaagtagt tcatcttgtc tcctgtaatc tccttttttc catcttattc
    10261 tgacaattct cgaataatag ccgcaatttt ttccgattct gaccattgta aataatggtg
    10321 attccctcct aaaatgagtt tagtattgga agtccaatat tctgattctc tgtactcttt
    10381 ttctctataa gtctgacaaa aaataaatac agggacatga gattctatcg acaaattctc
    10441 aaaatcttcc tcagtaatct ctccagatat ctgaaattct ggatcttgat tttccaactc
    10501 taagcctttt tcttgcatta attcccagat ttttttattc gtttcaggac taaatgttgc
    10561 ttgagttaag ttcttaaaat aaagttcagg accacactcg tcaatcagcc tcatctgctc
    10621 ttccatttct ggataaggat tttctgaaaa atcagcaaac atgacttttt tagttgtcgg
    10681 ttcaattgct actaaagtct gacacttaat tggtttctcg agtaatttgc aagctaaaat
    10741 tccactccaa ctatgtacac aaagtatata ttcagaaatc cctaattctt caagtgcttc
    10801 ataaaccaca tctgcaagat tatctagatt ttttccagct tggtcatgaa tcggactcct
    10861 acctgtgttc ggaaaatcaa ttgtcaaata accaattgta ggaggaggtt tttcaagtat
    10921 aagtgaaaaa ttttcataac ttggtagcaa acctgctccg tttagacaaa ctagcacttt
    10981 cttttgcttt tgataagcaa cagagagact accaatttct gtagatactt caaacctctt
    11041 cataaagaaa tccactgatt ctatataatg aattattaaa aatccttatc ctttatttta
    11101 tcacgttcca aggattttct caagttggag gaaggggaca acatctctac tttcccttca
    11161 agaatccttc caaatcatgt ttatgttggt aattaacggc tgcggttttg tctttctcaa
    11221 agatggttct agttaggtca atatgcttga tagcagcaat agcgacggtg tagtgaatga
    11281 tatcagccag ttctctggca agttcctcgt tcgaatccta tcccttcttt tcgaccagag
    11341 cgcctattca aaacctcggc tacttctccg acttcctcca ctaacttcat aaagagacct
    11401 tcatcagtcc gagactgctg t
//
LOCUS       DAVHSY010000049        11215 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.050, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000049 DAVHSY010000000
VERSION     DAVHSY010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11215
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.050"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(57..446)
                     /locus_tag="VVR43_001775"
     CDS             complement(57..446)
                     /locus_tag="VVR43_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU6150092.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(500..1192)
                     /locus_tag="VVR43_001776"
     CDS             complement(500..1192)
                     /locus_tag="VVR43_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6150093.1"
                     /translation="MNTSFVHAVDGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVIKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTRTRTYDVNPETGHVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDGSTLDKSQEVEEVG
                     EIGKLLLLQSIL"
     gene            complement(1908..2459)
                     /locus_tag="VVR43_001777"
     CDS             complement(1908..2459)
                     /locus_tag="VVR43_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6150094.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(2809..3633)
                     /gene="nadE"
                     /locus_tag="VVR43_001778"
     CDS             complement(2809..3633)
                     /gene="nadE"
                     /locus_tag="VVR43_001778"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU6150095.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(3630..5090)
                     /locus_tag="VVR43_001779"
     CDS             complement(3630..5090)
                     /locus_tag="VVR43_001779"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU6150096.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMHNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(5206..5694)
                     /locus_tag="VVR43_001780"
     CDS             complement(5206..5694)
                     /locus_tag="VVR43_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150097.1"
                     /translation="MKNRFYYYQLLDEREEQLINKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(5684..5893)
                     /locus_tag="VVR43_001781"
     CDS             complement(5684..5893)
                     /locus_tag="VVR43_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6150098.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(6279..7007)
                     /locus_tag="VVR43_001782"
     CDS             complement(6279..7007)
                     /locus_tag="VVR43_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6150099.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLGLLISFIPPILVTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            complement(7023..7814)
                     /locus_tag="VVR43_001783"
     CDS             complement(7023..7814)
                     /locus_tag="VVR43_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6150100.1"
                     /translation="MNFALNKGEIVGLAGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     VGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQEIFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            complement(8250..8978)
                     /locus_tag="VVR43_001784"
                     /pseudo
     CDS             complement(8250..8978)
                     /locus_tag="VVR43_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(9238..9549)
                     /locus_tag="VVR43_001785"
     CDS             complement(9238..9549)
                     /locus_tag="VVR43_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150101.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(9564..10850)
                     /locus_tag="VVR43_001786"
     CDS             complement(9564..10850)
                     /locus_tag="VVR43_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU6150102.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
BASE COUNT         3404 a         2386 c         1840 g         3585 t
ORIGIN      
        1 tatataatta tatattcaga catactatta tcaattttgt cgcagggagg aatctgttaa
       61 cgcacccatt caccattatc attgactcta tagccatcta tacttgtatt gaccgctaac
      121 tcacccgatg tatttacata ataccattta ccaccaactt ggaaccattg attgactttc
      181 atagaaccgt tgctgttgag gtagtaccat gaaccattaa cttgtaccca acctgttgcc
      241 atggaaccat cagtattata aaaataccac ataccatttt cttgtttcca gcctgttgtt
      301 ggagcaactg ctttagctgg ttctactgct acatctgttc cttggttaga tgtaacagat
      361 acaggatacg aaggaataga tgattgctca ggaacaacaa ctttttcagg ttctctcgtc
      421 cctctcctta tacgtctttt taccatctct ttagtaattt gacgagaagt agtttcttca
      481 attgttccat cacgttcatc tacagtatag attgtagtaa gagtaattta ccaatttctc
      541 ctacttcttc tacttcttga cttttatcaa gagttgagcc atcgagatat tctgtttcga
      601 ttggaatttc ttggacaaga acttggggct tggttccttt tttaacaact cttgtttgag
      661 agtcttcttt ttgacttaaa gtactctcag ttacttgtcc actctttcca tctacatcat
      721 aagttatcgt tgtaactgtt ttcccattct ttcctagagt aatctcttgc tcctgtcctg
      781 cagaaaggtc attgtctgct tcatatttag tagcacatgg aacaagaact tcttcaacct
      841 tgcttttagc tggaactttg ataactgtat ccgtggcttc ttttctatca acagtaacct
      901 gttcggtaac atgaccagtc tctggattaa catcgtaggt ccttgtccta gttacatagc
      961 catcctctcc atcaattgta acaggatttt cactacggtc ttttgtttca tctttttcat
     1021 aacgaattcg cgtacttgaa attttcttga ttactacctt aggtttagtc gctactttta
     1081 caataatatc cccattgtca gcgtcatcat actctattcc ctcttcttta tctctagtat
     1141 catctctgac atattgaatc ccatcaacag catgaacaaa acttgtattc agattcctcc
     1201 taaaaataaa gttagcccga ttaccgcaga accaaaaatc tttccgagtt tacgtaatgc
     1261 atagcgctta ttagtattag attttgccat tacatcctac ttctagtata gcatcttttc
     1321 tatcaaacgt taaacaatat attttatata tcaaatagac ttagaatgat atattgatta
     1381 ttgaactaac actttaacta tatcgtaatc aatctcatat ataaaggatt gcagacatct
     1441 tatctaaata catgctaata tatttagata caaacattcc aacttgataa ttttcactca
     1501 tctttcatca ttccttatac aactatgcag tataaataga atagttttct catcagaatg
     1561 agactatttt aatattagat attttgatag aaaaaaacat aaataaaatt ggttgaattt
     1621 aattccctaa ctcgatagag gattctattt taaatttaac aacagctagg attacactat
     1681 aaaaagcaca ttaccacctg ttcggctgga gaatctagtc gattagctcc ctcttagtta
     1741 caagcttcaa gcgatttttt aactaatact aaaccagatt aaagaagaaa ctagaacatc
     1801 tgtcttgtac taatcaatat gctattttaa agttgcaaat aaacttggaa tgctaattat
     1861 tatatttaca ataaatagtt gacttcgata gaaacagaaa atagaattca acattcttcc
     1921 ctacttatac cataataaat aagatccgca agatagcctt ttctctctac accattaaca
     1981 atggtttgta gataggacat tccagccttt tccatgacac gacctgaagc tgggttgaga
     2041 ctggcataac gtgctctgac cttttgaaaa cctgcttgag taaaacaaaa gtccaagaca
     2101 gctttcaagg cctctgtcat cataccatgt ccccagtaag ccttgcctag cacatagcca
     2161 atttcacagc ttaaatcagc ctcgtctatc ttaacaatgc tgatatctcc tatcacttgc
     2221 tctgggtttt cttttagaca aatggcccat ttgtaatagt tgagattagt ataggaagca
     2281 acccaattgc gaatcgagtt tcgagtgatt tcgacatcag gatggggatc ccaggtaaca
     2341 taggtcaaat tctcagcgga tgaagcccaa ttttgaaaca tggcttctgc atcactctcc
     2401 acaaatcttc ttaaaatcaa acgttctgtc tgtaatattt gcgtaccgat agatttcatg
     2461 atgctacctc acttccttat ttctatgctc gtagtaaaaa gactcaactc agtaacagct
     2521 agaaaacgag tttgtcttct aatttcttga cgcagtcgct gcctggtttg aaatgcgctc
     2581 tagcaagctt tttcaaacct agtcatcgtt gcaggggtaa gacgatgaaa tcgaactctt
     2641 cgagttactg aatctgcctc attttcttat ttctaaactc ggggttcaag atcccccaga
     2701 ccttctctca ctttcttatt tcaagatgag aggctgaaaa cctccagtgg aggtttttct
     2761 tgctttttaa tttcagggta agaagctaaa aaggtccccc ggaccttttt actcccaaaa
     2821 gtcatcaaat acggtgatgg gtaagtggcg tttgtgttgg cctttgtgcc accagttttc
     2881 aatggtcgct tgagcttctg ggctgattgt tttgccttct aggtagtcgt caatctctgc
     2941 gtaggtgact ccaagtgcga cttcgtcagc taggcctggt ttatcttctt ctaggtctgc
     3001 cgttgggatt ttttcataaa gggctggctc tgcgccaagt ttctgcaaga gctgttttcc
     3061 ttggcgttta ttgaggcggt aaagagggag aatatccgca ccgccgtcac caaacttggt
     3121 aaagaaacct gtgatatttt ccgcggcgtg gtctgttcca atgaccgctc cgctatggga
     3181 accagcaagg gcatactgag caatcatacg gcaacgtgcc ttgatattcc ccttgttgaa
     3241 gtctgaaaca ggactacctg tcgcttcaac tgcagctgtc atggcatcag ctgattcctt
     3301 gatattcaca accaagctga catctggctg gatgaaggct agggcttttt gagcatctgc
     3361 ttcatcagct tgcactccgt atggcaggcg gacagcgata aatttgtagc tatcgtctcc
     3421 cgtttcagct cgcagttctt ccatagctaa ttgcgccaaa cgtcctgcca aggttgagtc
     3481 ttgtccccca gaaatcccta gtacaaaggt ttttaggaag ggatgttttt tcagatatct
     3541 ttttaagaaa tcaatagaac gacggatttc ttcctgggca tcaatcactg gtttgacacc
     3601 cagctcttgg ataatcgttt cttgcaaact cattcttctt ctccttcacc aagggcttcc
     3661 ttgcgcatct tatcaatcaa gtccatctta tcttgccata catcacgcgc caaatccact
     3721 ggatagtgct gcggattgag cacacgctta tactcatccc acaacttgtc aaattcctta
     3781 cgggcataat cctgaatgtc agtcaaacta ggcaagttgt aaactaatat tccttctttg
     3841 aagatatcca ccaagagagg aacggcatca aaattacgaa ccgtcttctt gatgtatgta
     3901 taggtcggat ggaacatctt gatttctgtc atgtcgctaa tatccacacc atcataagtg
     3961 atgtagtcac cttctgactt gcctttttca cgactggtaa tgcgccacac ctgcttctta
     4021 cctggcgtcg acactttttc cgcattatta gacagcttaa tcgtattgtg catctgacca
     4081 gtttcatctt caattgcaac aatcttgtaa accgccccaa gagccggctg gtcataggct
     4141 gtaatcagct tggtacccac accccagaca tcaatcttgg ccttttgcat cttgaggtta
     4201 aggatggtat tttcatctag atcattagaa gcataaatct tagcctctgt aaatccagcc
     4261 tcgtccagtt gctgacggac tttcttagaa atgtaggcaa tatccccaga gtcaatccgc
     4321 acacccataa agttaatctg atcacccagc tcacgcgcca cctgaatggc agctggtaca
     4381 ccgatgcgaa gggtatcata ggtatccaca agaaagacac aatttttgtg ggtcgcagcg
     4441 taagccttga aagcctcata gtcattgcca taaacctgta ccaaggcatg ggcatgggtt
     4501 cccaaaacag gaatgtcaaa gagcttaccc gcacgcacgt tgctggttcc attggcgcca
     4561 ccaatcaccg ctgcgcgtgt tccccagatg gccgcatcca tttcttgagc ccgacgtgtc
     4621 ccaaactcca tcaagggttc atcttcgata accgaacgaa tacgagctgc cttcgtcgcc
     4681 accaaggtct ggtagttgac gatgttcaaa agagccgttt cgaccaactg acattgggct
     4741 agaggtcctt ccacctgcac aatcggttca ttagcaaaaa ccaaatcccc ttcttgggca
     4801 gaacgaacgg tcaactccaa cttgaaattg cgaaggtaat ccaagaacgc cccatgataa
     4861 ccaagcgact ccaaataggc tatatcacta tctgaaaaac gcaagtcttc aagatagttc
     4921 acaattcttt ccaaacctgc aaaaaccgca tagccgttct taaaaggctg ttggcggaaa
     4981 tacacctcaa agaccgcctt cttattgtga atcccttggt caaagtaaac ctgcatcatg
     5041 ttgatctggt acaagtccgt gtgcaatgtc aaactatcat ctggatacat acttttccta
     5101 cttccttagc tagaaaccca tgaaaatttt caagaacttt catgtattcc aataaattag
     5161 tactattata tcacatttta gctggattga gaaaagagta acaagctatt ctccactctc
     5221 caattcatcc atatcttgtt caaatttttt ctgagcccat tcgccatagc tcttaagacc
     5281 aagattgcca ataaagaccc acggaaggta aatgacataa gtaatgaccc aagcagacag
     5341 gtatttaaaa ttcaaaggat tgtgctgata aatttctatg ttgaattgat aattctgcaa
     5401 catcaaaaga gccgtaatag ccaaggttag gaaaaaacaa cccaaaatcg taaaatgaaa
     5461 acgactatag taggtcactc ccagataacg ggcacggtta aaaaagtaaa atgtccctat
     5521 gatgataacg attagcagca tattagaatt aaaaaggctt ggtgctaata ctgaaatgat
     5581 ataagatagg agcgacaaag cgatgcagat atagaaactt tcagagcccg ctttattgat
     5641 cagttgttct tctctttcgt ctagtaattg ataataataa aatctatttt tcatcttctt
     5701 cctcccaaaa tagttggtct agggttttcc ctaaacatct gcaaatagac tggcagagcg
     5761 agagactggg attgtatttt cccgcctcta tcaaaccaat agtctggcgt gtcaccccga
     5821 cagcctctgc cagttgacct tgtgttaaat cacgctctac ccgagctaat tttaatttta
     5881 aatttttagc caccttcgtc ctccttatag ttttaatact catctactct taaaaaatcc
     5941 aaaaccaaca caagctatca gctatttatt ataaccccat taatttgcac tccagtatta
     6001 tcttcagccg aaaatcagta ttttaggttg tttgaaataa acttcctagt ttactctttt
     6061 atttttattt agtattagct ttagtaggat cttttaaacg agtttttatt gcttatattt
     6121 cttgtttagt ttagttggtt tcatatcact attatataat gcttttggaa atgagcctag
     6181 tataagtcaa aaacgtgttg aatagtgaaa gcaggagcat accaagatga ctgatttttt
     6241 tattgtattt taggtatgca aaataatact aaatgaaact aaaatgaata cttcttgctt
     6301 ttcttgagag tgaaaaagta caataaaatg attgtagtga ttaccacaag atactgacta
     6361 atagacatcg tatttgaagc cacaaataca ggtaaagaat aaaaaggaag aagttcaatt
     6421 gctttgataa acaaatcatt actagtattc atcatcatcg tatttaatat attagggata
     6481 aagagtagta aagctactaa aataccaaat accaagccac ttttcaattt gtataaatag
     6541 aaaatgtaag ataatagaaa ataaaacagg actaacaaaa ttgtattgac tacaatagct
     6601 actataaaat ctaatcctaa atcacctgga atacccaatt tacttactat gactagtaac
     6661 acaatgccat tcaaagcata aataatggaa actgagatgg catatagaaa attagacaag
     6721 acgtaaatca tccgattctt ctgttgatta taaaacaaac ttaccgtatt gtgggaaaaa
     6781 tctctactaa tgactcgatt agcatgtata acagccatta acataccgag catagcataa
     6841 aagtttgaaa tatgcttaat accaagcgat gtcccttgag tctttagaat aaagaatgta
     6901 accaatatcg gcggtataaa cgagataagc aaaccgagat atattacgcc tgatgaatat
     6961 aaatttctta tattttcctt aagaaaattc aatttattta atttcatgat tataaccttc
     7021 ctttattttg aacgatttag gtaaatatct ttaagcgtct cttttttagt ttcaaaatca
     7081 actactttaa tagagttttc gttaaaaaat ttaaaaagct cactactttg aatattccca
     7141 gacatagtaa ttctcaatcc ctcttcctga acaatatctc caaattcttg tttggtaatg
     7201 aaaatgtctc tatctgtagc tgatgaaaaa gctatctcaa acaagaaatt atgactatct
     7261 tttcctactt tttgaaatgt caaaagcccg ttctccaaga aaagaactct ctcacaaatt
     7321 tcttcaatgt cttctaattt atgactcgat attaaaattc ccacattttc atgtaaagct
     7381 aaatttttta gaaccgctaa aactatttgt gatgattcaa tatctaaacc attagtcggt
     7441 tcatctaaaa tcaatatatc aggttccgta acgagagtta gaagcaaagc taatttttgt
     7501 tttgtaccca aagaataggt ctttactttt ttattaatag actgagtcaa atctaactct
     7561 tggatcaaac ttctaaatat ttcttgattg tagtcaacac catataaatt tgacaaatat
     7621 tttaaattct ctaaacctgt tttagataaa aataattttg gttcttcgat taaataccca
     7681 acattatcac tgcttataat attacctgaa gtcggttgat tattctgaac aagaattttc
     7741 atcaacgtac tcttaccaac tccatttctc cctgctagac caacaatttc acccttgtta
     7801 agtgcaaaat ttatatcttt gagaatgatt gaatgaccat aatgcttact tacatttata
     7861 acttacattt tttattcctc cattaatatt catggtttgc tctttgattc ttattgagtt
     7921 taaaaagttg cacctctttt taacaatatt atatcatata tctaactcaa tgcaatatat
     7981 aaatgtcatt ttgtaaaatt ttattaacaa aaaactctct acaacaaaat aatagagagt
     8041 tttctgctta ttaatttttt tcaaaatatc taagacatcg cttctttgtt taatttgata
     8101 ggctttaata cctaagctcc gactttatca cttaaaaaat aaaaaaggac agctaatctc
     8161 ttgcgcatca agggatttcg ccattcttta atctcgttta agtgttgtat atggagcttt
     8221 gcataatttt ttaaaactaa acaactacat taagcacgaa ctgtgacgct ggttccatct
     8281 tccttataaa gattgataag cccctcttta agagctcgaa ccatgtctcc agcttgaaca
     8341 ggttgtggga ctttaatagt caatagttcc attggatttg gagcgcggtc gattttattg
     8401 cctttggcat catgcaaatc ttcaatatag gtttcaaaat gacggaaacc tggaccataa
     8461 aactcaactt ggtccccttc gttaatgacg tttcgttgac gaatagttgc tgtttgtgcc
     8521 gcatcatcat aagaaaccac ttcagcgaca aacttgtact cagggatttt acgacgagca
     8581 ccaaacaact gctcattttc agatggtgta ccatagtaaa atcctgtagc cagttcacgt
     8641 tgggcaacct tccacatctc gtccaccaag tcttgtttga tagcttcaaa cttttcagga
     8701 ctttcaagat aggcatccac agccgccttg taacagttgg ttactgttga tacatagtga
     8761 atagactcca tacgtccttc gatttttaga ctgtccacac cattttcaat catatctgag
     8821 atatggtcaa tcatagacat atcaacggct gacattgaaa attcttctgg aatctcaccc
     8881 tgcaaactct tacgttcttt cccaaatggc atatcgtaaa ggtcgtactt ccaacggcat
     8941 gactgagaac atccaccacg gttggcatca cgcatactct agacggattg ttttgacaat
     9001 tctaaccttt tagactttgc ataataactg ttaaacagtc gaaaattacc ccagttttaa
     9061 caagtagtca aaataccaga taaagtaaaa aggggctagg aaaaaagtct ttaaaatctt
     9121 aaaaacgcat agtatcaggt attgaacaat cttgatatta tgcgttttat tgtgggaaga
     9181 tttacttcat tttctcttgg aattgagttt tctcctactt caaaactaga tgatttgcta
     9241 tttaaaatag cgttccttat gattttggca acctggatta aagcgagaaa aacaaaagag
     9301 gcaacttaag ctttctttat attgcttata tgttaatagt tttagacaaa caccacataa
     9361 aataggctta tcctgtatca aagataaggg ataaggctca aaagggtgat tttctaatga
     9421 atcatgacac cgataacaag cataatactt tttacaatca tagcattgta aagcaataat
     9481 atccagcttg ctatggtaat gaatgcatct tgtttgctta tccactaaga aaccctgtgc
     9541 ctctatcatt tccttttcct ttcttaagct cgaactgtga cgctggttcc atcttcctta
     9601 taaaaattga tgagtccttc ttttaatgca cgaaccatgt ctcctgattg aacgggttgt
     9661 gggactttaa tagtcaatag ttccattgga tttggagcgc ggtcgatttt attgcctttg
     9721 gcatcatgca aatcttcaat ataggtttca aaatgacgga aacctggacc ataaaactca
     9781 acttggtccc cttcgttaat gacgtttcgt tgacgaatgg ttgctgtttg taccgcatca
     9841 tcataagaaa ccacttcagc gacaaacttg tactcaggaa ttttacggcg agcaccaaac
     9901 aactgctcat tttcagatgg tataccgtag tagaaacctg ttgccaattc acgttgggca
     9961 accttccaca tctcgtccac caagtcttgt ttgatagctt caaacttttc aggactttca
    10021 agataggcat ccacagccgc cttgtagcag ttggttactg ttgatacgta gtgaatagac
    10081 ttcatacgtc cttcgatttt tagactgtcc acaccatttt caatcatatc tggaatgtgg
    10141 tcaatcatag acatgtcaac ggctgacatt gaaaattctt ctggaatctc accctgcaaa
    10201 ctcttacgtt ctttcccaaa tggcatatcg taaaggtcgt atttccaacg gcatgactga
    10261 gaacatccac cacggttggc atcacgcata ctcatgtggt ttgaaagagt acaacgtcca
    10321 gagtatgaaa tacacatagc tccatggaca aaggcttcaa tttcaacatc tgtacgtttg
    10381 cggatctcag ctaattcttc cattgaaacc tcacgcgcta aaacgacacg agtcaagcct
    10441 agctctttcc agaactcaag ggtttcatag ttagtggcac tggcttgggt agaaaggtgg
    10501 atttcaaggc ctggtgcttc agtcgctgca atcataatca aggctgggtc agatacgata
    10561 actgctgcaa tcccgatatc acgcagttta cggaaccact caccagcacc agcttcattt
    10621 ccttcgtgca taaccatatt agccgctaca tagaccttgg caccatactt ggccgcaaac
    10681 tgcacgcctt cttccatctg ttcgaaagta aagtttcccg cacggctacg aagaccatag
    10741 gcctgaccac cgataaagac agcatctgct ccatactgaa cagctacctt tagcttctct
    10801 aaagtccctg caggtgataa aacctcagga cgttttaatg tttttgtcat gatttctcct
    10861 atttgcaata taaaagtttg acatttttcc ttctcatttt atagtaaata aaggataaaa
    10921 tcaagcctag acggattgtt ttgacaattc taatctttta gactttgcat aataactgtt
    10981 aaacagtcga aaattacccc agttttaaca agtagtcaaa aagtctaaaa aagtaaaaac
    11041 cagtatccca agatactgac tcgtaaaaat acataaatta gtccttagat gactactccc
    11101 actctgttgc tcctataatg gaaaaggatt gatacagtct agaatatcgc ttttttattt
    11161 attattctga tataaaactg ttagaattga ttttttattt tataccaaaa tatga
//
LOCUS       DAVHSY010000050        11111 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.051, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000050 DAVHSY010000000
VERSION     DAVHSY010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11111
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.051"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            16..396
                     /locus_tag="VVR43_001787"
     CDS             16..396
                     /locus_tag="VVR43_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150103.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            590..880
                     /locus_tag="VVR43_001788"
     CDS             590..880
                     /locus_tag="VVR43_001788"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150104.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            931..1623
                     /locus_tag="VVR43_001789"
     CDS             931..1623
                     /locus_tag="VVR43_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU6150105.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1676..4087
                     /locus_tag="VVR43_001790"
     CDS             1676..4087
                     /locus_tag="VVR43_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU6150106.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4337..5038
                     /locus_tag="VVR43_001791"
     CDS             4337..5038
                     /locus_tag="VVR43_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6150107.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5040..7748
                     /locus_tag="VVR43_001792"
     CDS             5040..7748
                     /locus_tag="VVR43_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU6150108.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMSQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7844..8335)
                     /gene="tpx"
                     /locus_tag="VVR43_001793"
     CDS             complement(7844..8335)
                     /gene="tpx"
                     /locus_tag="VVR43_001793"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU6150109.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8458..9387)
                     /gene="psaA"
                     /locus_tag="VVR43_001794"
     CDS             complement(8458..9387)
                     /gene="psaA"
                     /locus_tag="VVR43_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU6150110.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9419..10267)
                     /locus_tag="VVR43_001795"
     CDS             complement(9419..10267)
                     /locus_tag="VVR43_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU6150111.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10264..10986)
                     /locus_tag="VVR43_001796"
     CDS             complement(10264..10986)
                     /locus_tag="VVR43_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU6150112.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT         3255 a         2067 c         2540 g         3249 t
ORIGIN      
        1 aaaggagatt ttattatgaa attaaaaaca cttgctttaa ttagtggtat cgtcggtctt
       61 gtgggaggaa ttttacttct tattggtcct tttgtcttgt tgggaacagc ggtaaacaca
      121 gttgctacaa ctcttaatgg aggagctact gcaggggctt tttcaggtgt tgccttactc
      181 ttgaatgcct tgaagattgc aaatcttgtt cttggtatca ttgctattgt ttactataaa
      241 ggagataatc gtgtaggtgc agctccgtct gtactaatga ttgtttttgg tggagttagt
      301 ctcattccat tcttaggatg ggttgggggg attcttgtta ttatcggagg atctctattc
      361 cttgcaacat tgaagaaatt caaatcagaa gaataaaagg tattttagca tgaaaagaac
      421 aaaaaagttt atcggtatag gagtagctct attatctctt tttcttctag ttgcatgtgg
      481 aacataaagt tcaaaggata cttcaacaag taatgatgag aagacagtag caacatccaa
      541 tagttcaaaa gaaacaatca ctttcgatac accggttgta acagacgatg tgattgaatc
      601 aatacgcact tatgcagatt atatagatct ttataaaaat atttttgatg attattttac
      661 taaagctgag gaaggtttca aaggcacagc tatggaaaat aatgactcgt ttactaaact
      721 aaaagagtca actcaaaaat tattcgatgc gcagaaaaaa aggttaaata atgaagatag
      781 aatagaaaca actaaaaaca atgtgattgc caaacattgt caaacagtcc tttccttttt
      841 ggttttgact agcttttttg tgaaaaattg tgtaaaatag aatagataaa cgaggggaaa
      901 cctcggaaaa tttaaaggag aatccatcta atggtaaaat tggtttttgc tcgccacggt
      961 gagtctgaat ggaacaaagc taaccttttc actggttggg ctgatgttga tttgtctgaa
     1021 aaaggtacac aacaagcgat tgacgctggt aaattgatca aagaagctgg tatcaaattt
     1081 gaccaagctt acacttcagt attgaaacgt gctatcaaaa caactaactt ggctcttgaa
     1141 gcttctgacc aattgtgggt tccagttgaa aaatcatggc gcttgaacga acgtcactac
     1201 ggtggtttga ctggtaaaaa taaagctgaa gctgctgaac aatttggtga tgagcaagtt
     1261 cacatctggc gtcgttcata cgatgtattg cctccaaata tggaccgtga tgatgagcac
     1321 tcagctcaca cagaccgtcg ttatgcttca cttgacgact cagtaatccc agatgctgaa
     1381 aacttgaaag tgactttgga acgtgctctt ccattctggg aagataaaat cgctccagct
     1441 cttaaagatg gtaaaaacgt attcgtagga gctcacggta actcaatccg tgcccttgta
     1501 aaacacatca aaggtttgtc agatgacgag atcatggacg tggaaatccc taacttccca
     1561 ccattggtat tcgaattcga cgaaaaattg aacgtcgttt ctgaatacta ccttggaaaa
     1621 taaaaaattg taagtctaga attgatttct aggcttttta tgttagtatg gaagtatgat
     1681 aaggaataaa aaacaagatt atgtactggc ctacaagcaa ccagtttcaa ccacttacat
     1741 gggttgggaa gaagaagctt taccgatagg caatggttct ttaggagcaa aagtatttgg
     1801 ccttataggg gctgaacgga ttcaatttaa tgaaaaaagt ctctggtctg gaggtccact
     1861 tcctgatagt tcagattatc agggtggaaa tcttcaggat cagtatgttt ttttagctga
     1921 gattcggcag gctttggaga agagagatta caatctggct aaggaactgg ctgagcagca
     1981 cctaattggg ccaaaaacga gtcaatatgg gacctatctg tcttttgggg atattcacat
     2041 tgagttcagc cagcaaggta cgactttgtc tcaggtgacg gactatcaga gacagctgaa
     2101 tattagtaag gcacttgtga cgacttctta tgtctataag ggaacgcgat ttgaacgtga
     2161 agcttttgcg agttttccag atgatctctt ggttcagcgt tttactaagg aaggggcgga
     2221 aactctagat tttactatag aactatcctt gacctgtgat ttggcttctg atggaaagta
     2281 tgagcaggaa aaatctgatt acaaggagtg taagttggat attactgatt ctcatatctt
     2341 gatgaaggga agagttaagg ataatgatct gcggtttgct agttatctag cttgggaaac
     2401 ggatggagat attagagttt ggtcagatag ggttcagata tcaggagcca gttatgccaa
     2461 tctcttcttg gccgctaaga cggattttgc ccaaaatcct gctagcaatt atcgcaagaa
     2521 actagattta gagcaacagg tgatagactt ggtggacaca gctaaagaaa agggctatac
     2581 ccaattgaaa tcaaggcata tcgaggacta ccaagcctta ttccagcgtg ttcaattgga
     2641 tttggaagct aatgttgacg cattcactac agatgatttg ttaaaaaatt ataagccaca
     2701 agaagggcag gctttggagg agctgttctt ccagtatgga cggtatttat tgattagttc
     2761 gtccagagac tgcccagatg ctctaccagc taacctacag ggagtctgga atgcggtcga
     2821 caatcctcct tggaattcgg actatcactt aaatgtcaat ctgcagatga attattggcc
     2881 agcctatgtt accaatctcc tagaggcggt ctttccggtc atcaactatg tagatgattt
     2941 gcgtgtctat ggtcgtctag cggctgtaaa gtatgcagga atcgtctctc aaaaaggtga
     3001 ggaaaatggt tggttggttc atactcaagc gactcccttt ggttggacgg cacctggttg
     3061 ggattactat tggggttggt caccagctgc caatgcgtgg atgatgcaaa ctgtttatga
     3121 agcctattca ttttataggg accaagacta tctcagggag aaaatttatc ccatgttgag
     3181 ggaaacggtt cgtttttgga atgccttttt acataaggat cagcaggcgc agcgttgggt
     3241 gtcttctccg tcttattccc cagaacatgg gccgatttcg attggcaata cttatgacca
     3301 atctctgatt tggcagttat ttcatgattt tattcaggct gctcaggaat tgggactgga
     3361 tgaggacttg ttgactgagg ttaaggagaa gtctgattta ctaaatcctt tgcaaatcac
     3421 tcaatctggt cgaatcaggg agtggtatga ggaggaagag cagtattttc aaaatgagaa
     3481 agtggaggcc cagcaccggc acgcttccca tctagtggga ctctatcctg gcaatctctt
     3541 tagctacaag ggacaagagt atattgaagc ggcgcgtgct agcctcaatg atcgtggaga
     3601 tggcggcaca ggctggtcca aggctaataa gatcaatctc tgggcgcgtt tgggagatgg
     3661 caatcgagcc cataaattat tggcagagca gttaaagaca tccaccttgc caaatctttg
     3721 gtgtagccat cctccttttc agatagatgg taattttggt gctactagtg gcatggcaga
     3781 aatgttactc cagtctcatg cagcttatct ggtacctcta gctgccctac ctgatgcttg
     3841 gtcaacaggt tctgtttcag gcttaatggc acgtggacat tttgaagtga gcatgagctg
     3901 ggaagataaa aaactcttac agttgaccat tttatcaagg agtggaggag atttgcgagt
     3961 ttcttatcca gatattgaga agagtgtgat taaaatgaat caagaaaaaa taaaagcgaa
     4021 atgcatgggg aaagattgta tttcggtggc aacagcagaa ggtgatcttg ttcaatttta
     4081 tttttaagaa gatgttataa ggcagtaatt tgaaactgcc ttttaataag gatttaagaa
     4141 tataagcagt tttcaactag ttgaaaaagc gttataatga taataggaag taatactcaa
     4201 tgaaaatcaa agagcacaaa caaggaagct agccgcaggt tgctcaaaac agtgttttga
     4261 ggttgcagat ggaagctgac gtggtttgaa gagagatttt cgaggagtat aatttgtttg
     4321 atagagggtg ggtctgatgg cttatattga gatgaaacac tgttacaagc gttatcaggt
     4381 tggggacacg gagattgtgg ccaatcgtga tgtgaatttt gagattgaaa agggggagct
     4441 ggttattatc cttggtgctt caggtgcagg caagtcaaca gtgcttaacc ttcttggggg
     4501 aatggatacc aatgatgaag gggaaatctg gattgatggt gttaatattg cggattatag
     4561 ttcccaccag cgcaccaatt accgtagaaa tgatgtgggg tttgtttttc agttttataa
     4621 tctagtttct aatctgacag ctaaggaaaa tgtggaactg gcttctgaaa ttgtgacaga
     4681 tgccttgaat cctgatcagg tcttgacaga tgtaggtctg gctcatcgtc tcaataactt
     4741 tccagcccag ctttctggag gggagcaaca gcgagtctcc attgcacgcg cggtagccaa
     4801 aaatcctaaa attctccttt gtgatgaacc gactggagcc ttggattatc agacgggcaa
     4861 gcaggttttg aaaattctcc aagacatgtc tcgtcaaaag ggagcgacgg tgatcatcgt
     4921 gactcataat ggagctttgg cgcccattgc tgatcgcgtg attcatatgc acgatgccag
     4981 tgtcaaggat gtggtgctca accagcatcc tcaggatatt gacagtttgg agtactagca
     5041 tgatcaagcg aaaaacttat tggaaggact taattcagtc cttcacagac tccaaggggc
     5101 gttttttatc catcttgatc ctgatgatgt tgggatctct agccttagta ggcctcaaag
     5161 taaccagtcc caacatggag gcgacagcta atgcttattt aacaactgct caaaccttgg
     5221 atttggcagt catgtctaac tatggcttgg atcaagcaga ccaagaagaa ctaaaacaga
     5281 cggagggcgc agaggtcgag tttggctatt tgacagatgt gactatggat aatgggcagg
     5341 atgccattcg actgtactcc aaaccagagc gaatttcaac ctttcagcta agaaagggac
     5401 gacttcctca gtcagacagg gaaatcgctt tggccactca tttgcaaggc caatacagcg
     5461 tgggacagga gattagtttt aaagaaaaag aagagggtca ttcctcttta aaagaccata
     5521 cttataccat tactggtttt gtggattcgg ctgaaatcct ctcccagcga gatatgggct
     5581 acgcaggaag tggaagtggg actctgacag cctatggggt gattttacct agtcaatttg
     5641 atcagaaagt ctacaatata gctcgtttga aatatcaaga tttagcaggt ttaaatgcct
     5701 tttcatcagc ttatgaagaa aaatccaagc aacatcagga agaccttgaa caaactttat
     5761 cagataatgg caaggtacgt ctgcaacttt tgaaaaaaga aggacaagag tctctagaca
     5821 aggggcaaga gactcttgac aaggctcaga ctaatttgca ggaaggcaag cgtcgtttag
     5881 cagctgctca agctcgtata caggctcaag aaagtcaact agccttgttt cctcaagctc
     5941 agagagagca ggctagtgct caacttaccc aagccaagca ggaactgggc aaggaagagg
     6001 acaaactaaa gcaagctgaa caaaatctag cccaagaaaa ggaaaaatta gaaaaacatc
     6061 agcaagtctt ggatgatttg gcggagccaa ggtatcaggt ttataatcgt cagaccatgc
     6121 caggtggtca gggctatctt atgtatagca atgcttcatc cagtattcga gcagtgggca
     6181 atatctttcc tgtggtactt tatgccgtag cagccatggt gacctttacg accatgactc
     6241 gctttgtaga cgaagagcga actcatgcag ggatttttaa ggccttgggt tatcgtagta
     6301 aggatattat cgccaagttt ctcctttatg gactagtagc tgggactgtc ggaacggctc
     6361 taggtagtat acttggtcat tatttgctag ccagtgtaat ttcaagtgtc attacaaaag
     6421 gcatggtggt gggagaaacc cagattcagt tctattggac ctatagctta ctagctcttg
     6481 tcttgagctg gttggcgagt gtgttaccag cctatctggt ggcttggagg gaacttcatg
     6541 acgaagcagc ccagcttcta cttcctaaac ctcctgtcaa aggagctaaa atcttattgg
     6601 agcgtatcgg ttttatctgg cgtcgtctca gttttactca taaggtaaca gcccgcaaca
     6661 tctttcgtta taagcagaga atgttgatga caatctttgg tgtggcaggt tctgtagctc
     6721 tgctctttgc aggtttggga atccaatctt ctgtagcagg agttccgtct aaacagtttc
     6781 aacaaatcca acagtatcag atgcttgtct ctgaaaatcc tagtgcgacc aatcaggaca
     6841 aggtagagct agcagaagtg ttgaaagggc aggagatact agcctaccag aaaatctatt
     6901 ctaaaacgct agacaaggat ttcaaaggca aggctggtct tcaaaacatt actcttatga
     6961 tgatagagaa ggaagatttg actcccttta tccatcttca acatcatcag caggagctga
     7021 cattaaaaga tggcatcgtt attacagcta aactcgccca gctggcaggt gtcaaggttg
     7081 ggcagacttt agaaattgaa ggtaaggaac taaaggtcgc tgctattact gagaactacg
     7141 ttggtcactt tatttatatg agtcaggcta gctatgagca actttacgga cagctacccc
     7201 aagccaacac ttatctggtc tcattaaggg ataccagtgc aactagtatc gaaagtcagg
     7261 cgggcttgct tatgagtcaa tctgcggtgt ccagcgttgt ccaaaatgct tcagccattc
     7321 gactcttcga ctctatcgct agctcactca atcagaccat gaccatcttg gtcatcgtat
     7381 cggttctatt agctattgtc atcctttaca atctgaccaa tatcaacgta gctgagagaa
     7441 tccgtgaact ctccactatc aaggttctcg gttttcataa taatgaagtc accctctaca
     7501 tttaccgtga gacgattgtg ctgtcccttg tgggaatcgt acttggtctg gtagctggtt
     7561 tctatttaca ccaatttttg attcaaatga tttcgcctgc gactattctc ttttatccgc
     7621 aggtaggctg ggaagtctat gtaatcccag tggcagcagt aagcatcatt ttgaccttgc
     7681 ttggtttctt cgtcaattat tatctgagaa aggttgacat gttagaagcc ctgaaatctg
     7741 tagagtaagg tagttatttt tagctgattg aacttctatt tactaatatt caaaaatcct
     7801 ccgtttcaaa gagcagggaa ctctttgtga cagaggattt tttctatagg gctttagcag
     7861 ctgcaattgc ggcttcgaag tttggctcag aattgatatt atccacgtat tcaacgtagc
     7921 gaatcgtatt gtcagtatcg aggacaaaga ctgcgcgtgc taataggtgc cattcgttga
     7981 tcaagagggc ataatcgcgt ccgaaagaat ggtcaaagta gtctgaaagc ataatggcat
     8041 tgtcaaggcc ttcagcaccg caccaacgtt tttgagcaaa aggtaggtcc attgaaacag
     8101 tcaatacgac cgtgttgtcc agtccagcca attcttcatt aaaacgacgt gtttgagttg
     8161 agcagatgcc tgtatcgata gaaggaacga cactcaagac ttttttcttg ccatcaaaat
     8221 cagccagaga ttttttagaa agatctgttg tagtaagaga aaaatcaagc gccttgtcgc
     8281 cgacttgtag ttgtttacct gtaaagctca caggatttcc gagaaaagtt accataggat
     8341 actccaatct tttttcttcc attgtatctg aaacagtcag aattttccaa tgatttgacc
     8401 ggaaatgtgt gcatagaaaa aacgccagct cacatgagaa tgacgttttt cagaggctta
     8461 ttttgccaat ccttcagcaa tcttgtcaag gttgtatttc atcatgctgt agtagctgtc
     8521 gccttcttta ccttgttctg cgatagagtc agtaaagatt tgtgcgtaga ttgggatgtt
     8581 tgtgtcttga gaaacagttt tcattggacg gtcatccaca cttgattcta caaagagtga
     8641 tggaactttt gtttggcgaa gtttttcaac caaggtcttg atttgttcag gagttccttc
     8701 ttcttcagta ttgatttccc agatgtaggc acttgggaca ccataggctt tagagaagta
     8761 tttgaatgct ccttcgctgg ttacaatgag tttcttttca gcagggatct tattaaattt
     8821 atccttactt tctttatcaa gtttgtctaa cttatcagta tattctttga gatttttttc
     8881 atagaattct ttattgttag ggtctttggc gctcaattgt ttggcgatat ttttagcaaa
     8941 aataataccg ttttcaaggt taagccaagc gtgtgggtct tcttttcctt tttcattttg
     9001 accttcaagg tagataacat caacgccgtc gctgactgcg aagtagtctt tgttttcagt
     9061 tttcttggca ttttctacca attttgtaaa ccaagcattg ccacctgttt caaggttgat
     9121 accgttatag aaaatcaaat cagcctcaga agttttctta acgtcttcag gaagtggttc
     9181 gtattcgtgt gggtcttgcc caatcggaac gatactatga aggtcaattt tgtcaccagc
     9241 aatattttta gtaatatcag cgatgattga gtttgtagca acaactttta gtttttgacc
     9301 agaagttgta tctttttttc cgctagcaca tgctacaaga atgattgcag aaagaaagag
     9361 aacgagtaat gtacctaatt ttttcattag atcctccaat ttattagggc tttgcccctt
     9421 attttaacaa atgtttattt ttcagtttca aatatcgttg tttgggagcg ataaagaagc
     9481 taatgagaaa gaaactagca gctgtaagca cgatactaga acctgccgca acattaaaac
     9541 tatagccaat aaagagtccc aaaactgaag cagtagctcc gaaggttgag gaaaggaaaa
     9601 tcatgctttt cagactatta gcatacagat aagcagttgc agctggggta atcagcatgg
     9661 ctacaatcag gatagttccg acactttgca tggctgtcac agacacgaga gtcaggagta
     9721 ccatgagaag gtagtgatag aaattgacag gcattcccat ggctttagcc aagagttcat
     9781 caaaggaagt tatcaagagt tgcttgaaga aaatccagat taacaagagg atggctgccc
     9841 ccacacccat agtaataaac atatccgtat cttggacggc cagaatatta ccaaaaagga
     9901 tatggaaaag gtcagttgaa cttttagcga caccaatcaa gatgataccg agggctaaga
     9961 aagaagaaaa ggtaatgccg atggcggtat cgcttttgat aatcgagttt cctttgatgt
    10021 aggtaatgat gatggcagct agcaatccaa agacaatggc tccgataaag aagtcaaggc
    10081 ccaagatgaa ggagagggct acacctggta agacagcatg tgaaatggca tctcccatga
    10141 gtgacatccc gcgtagaata atgaaacatc ccacggctcc agctacaatc ccgacgacaa
    10201 tagctgttat caaggcattt tgtaggaaat ggaatttttg caatccatcg ataaattctg
    10261 caatcatagg tcacctccat tgaaaaagag ttgattaccg taagcttctt ttagattggt
    10321 ttcggtaaaa gtttcttttg ttggaccaaa ggcaatcact tctcgattga caagtaagac
    10381 ttgatcgaag tagtggggaa tcttgctgag gtcgtggtga acgatgagaa ccgtcttccc
    10441 agcttttttc aaatctctca gcgtattcat gatgatttcc tcactgacag agtcaatccc
    10501 agcaaagggt tcatccaaga ggatatagtc ggcttcctgc accaaacatc tggcaatcaa
    10561 gacccgctgg aattgacctc cagacagttg actaatttga cgttcagcgt agtcagctag
    10621 gccgacgatt tcaagggcct cttgcacttt cttccaatgt ttagccttta aacttcgaaa
    10681 gagaggaata gagggaaata gtcctaacga gacgcattcc ttgaccttga tgggaaagtt
    10741 gtagtcgata ttgatttttt gttcgacata ggcaattcgg tgtaaggatt ttttaacttc
    10801 cttgtcatcg agaaatgcct gaccttgatg tgggataatt cccagcatac cttttaatag
    10861 tgttgatttc ccagcgccgt ttggaccaat gatgccggta attgttggtc catggagcac
    10921 tagtgaaata tccttaagtg ccaacgtttc tttgtaggag acactgaggt tttcgatacg
    10981 tatcataaac ttgtattcct cctgtctctt aatatacatt aaaaaaaaaa ttaagtcaag
    11041 ttaatttttg aaaaaattaa aataataact gaaaaataga ttctaaagat aactttcagg
    11101 ataaatttct a
//
LOCUS       DAVHSY010000051        10823 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.052, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000051 DAVHSY010000000
VERSION     DAVHSY010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10823
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.052"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            271..2199
                     /gene="glgB"
                     /locus_tag="VVR43_001797"
     CDS             271..2199
                     /gene="glgB"
                     /locus_tag="VVR43_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU6150113.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            2189..3331
                     /locus_tag="VVR43_001798"
     CDS             2189..3331
                     /locus_tag="VVR43_001798"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEU6150114.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            3321..4460
                     /gene="glgD"
                     /locus_tag="VVR43_001799"
     CDS             3321..4460
                     /gene="glgD"
                     /locus_tag="VVR43_001799"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU6150115.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            4457..5890
                     /gene="glgA"
                     /locus_tag="VVR43_001800"
     CDS             4457..5890
                     /gene="glgA"
                     /locus_tag="VVR43_001800"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU6150116.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            5949..6320
                     /locus_tag="VVR43_001801"
     CDS             5949..6320
                     /locus_tag="VVR43_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEU6150117.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            6265..6489
                     /locus_tag="VVR43_001802"
     CDS             6265..6489
                     /locus_tag="VVR43_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU6150118.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAE"
     gene            6603..7718
                     /locus_tag="VVR43_001803"
     CDS             6603..7718
                     /locus_tag="VVR43_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEU6150119.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(7715..8161)
                     /locus_tag="VVR43_001804"
     CDS             complement(7715..8161)
                     /locus_tag="VVR43_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU6150120.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKIWEVKKEEPAKTSLWKKWFS"
     gene            8325..9629
                     /gene="eno"
                     /locus_tag="VVR43_001805"
     CDS             8325..9629
                     /gene="eno"
                     /locus_tag="VVR43_001805"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU6150121.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            complement(9767..9904)
                     /locus_tag="VVR43_001806"
     CDS             complement(9767..9904)
                     /locus_tag="VVR43_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HEU6150122.1"
                     /translation="MPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKI
                     F"
     gene            complement(9945..10823)
                     /locus_tag="VVR43_001807"
                     /pseudo
     CDS             complement(9945..10823)
                     /locus_tag="VVR43_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT         3255 a         1898 c         2381 g         3289 t
ORIGIN      
        1 aatagtacac tttgatttct aagacattgt tagaaattag attaaattcc ttaatcgatt
       61 tgcgcatgtt ttatttcatt tcactatagt agaaaaagaa aggcgttttc gcaatttttt
      121 tgaaaaaaat actgatttac aattgaacga gtaagtgaac ttgttgtaga ttttcaaaat
      181 aattaaagaa gtatagtaat ttacttgaat cttctctaaa aaggtagtat aataaaaaca
      241 tagaaaacgc ttacaggaga aggggagtat atggataata gagaagcatt aaaaaccttt
      301 atgacgggtg aaaattttta tctccaacat tatctaggag cacataggga agaactaaat
      361 ggagagcatg gctatacctt ccgtgtttgg gcacctaatg ctcaggctgt tcacttggtt
      421 ggtgatttta ccaactggat tgaaaatcag attccaatgg taagaaatga ctttggggtc
      481 tgggaagtct ttaccaatat ggctcaagaa gggcatattt acaaatatca tgtcacacgt
      541 caaaatggtc atcaactgat gaagattgac ccttttgccg tcaggtatga ggctcgtcca
      601 ggaacagggg caatcttaac agagcttcct gagaagaaat ggaaggatgg actttggctg
      661 gcacgaagaa aacgttgggg ctttgaagag cgtcctgtca atatttatga agttcacgct
      721 ggatcatgga aaagaaattc tgatggcagt ccttatagtt ttgcccagct caaggatgaa
      781 ctcattcctt atctcgttga aatgaactat actcatattg agtttatgcc cttgatgtcc
      841 catcctttgg gcttgagttg ggggtatcag cttatgggtt acttcgcttt agagcatgct
      901 tatggccgac cagaggagtt tcaagatttt gtcgaggagt gtcataccca taatattggg
      961 gttattgtgg actgggtacc aggtcacttt accatcaacg atgatgcctt agcctattat
     1021 gatgggacac cgacttttga ataccaagac cataataagg ctcataacca tggttggggt
     1081 gcccttaatt ttgaccttgg aaaaaatgaa gtccagtcct tcttaatttc ttgcattaag
     1141 cattggattg atgtctatca tttggatggt attcgtgtgg atgctgttag caacatgctc
     1201 tatttggact atgatgatgc tccatggaca cctaataaag atggcggaaa tctcaactat
     1261 gaaggttatt atttccttca gcgcttgaat gaggttatta agttagaata tccagatgtg
     1321 atgatgattg cagaagaaag ttcgtctgcg accaagatta cgggaatgaa agagattggt
     1381 ggtctaggat ttgactacaa atggaacatg ggctggatga atgatatcct ccgtttctac
     1441 gaagaagatc cgatctatcg taaatatgac tttaacctgg tgactttcag ctttatgtat
     1501 gttttcaagg agaattatct cttgccattc tcgcacgatg aagtggttca tggcaagaag
     1561 agtatgatgc ataagatgtg gggagatcgt tacaatcaat ttgcaggctt gcgcaatctc
     1621 tatacgtacc aaatttgtca ccctggtaag aaattgctct tcatgggtag cgaatacggt
     1681 caattcctag aatggaaatc tgaagaacag ttggaatggt ctaacctaga agacccaatg
     1741 aatgctaaga tgaagtattt cgcttctcag ctaaaccagt tttacaaaga tcatcgctgt
     1801 ctgtgggaaa ttgataccag ctatgatggt attgaaatca ttgatgcgga taatcgagac
     1861 cagagtgttc tttcctttat tcgtaagggt aaaaagggag aaatgttagt ctgtatcttt
     1921 aatatggtac ctgttgagcg gaaagatttt acaatcggac tacccgttgc aggaatttac
     1981 gaagaagtat ggaatactga gttggaagag tggggaggcg tttggaaaga acataatcaa
     2041 actgttcaaa cgcaagaagg actatggaaa gattatgagc agaccttaac ctttacccta
     2101 ccggctatgg gagcaagtgt atggaaaatc aaacgtcgct tgaaatctac taaaaccgtc
     2161 acaaataaaa accaaaaagg agtagaaaat gaaaaatgaa atgttagctt tgattcttgc
     2221 tggtgggcaa ggaactcgtc tcggtaaact cactcaaagc atcgcaaaac cagctgtgca
     2281 atttggtggg cgctaccgta tcattgactt tgccctatca aactgtgcca actcagggat
     2341 tcacaatgtt ggggtcgtta cacagtatca accacttgct ctcaacaacc atattgggaa
     2401 tggttcaagc tggggactag acggtattaa ttcaggtgtc tctattcttc aaccttattc
     2461 tgcaagtgaa ggaaatcgtt ggtttgaggg gactagtcac gctatttacc aaaatatcga
     2521 ctatatcgac agtgtcaatc ctgagtatgt cttgattttg tctggggatc acatctacaa
     2581 aatggactat gatgatatgc tccagtctca taaggataat aatgccagct tgacagtagc
     2641 agttttagac gtccctctta aagaagcaag ccgttttggt atcatgaaca cagatgctaa
     2701 caatcgtatt gttgaatttg aagaaaaacc agctcaacct aaatctacaa aagcttctat
     2761 gggaatctac atttttgatt ggcaacgcct tcgtaatatg ttagtcgctg ctgaaaagag
     2821 caaggttggc atgtcagact ttggtaaaaa tgtcattcca aattaccttg agtcaggtga
     2881 aagtgtttat gcttacgaat ttagtggtta ttggaaagat gttggtacta ttgagtcact
     2941 ttgggaagcg aacatggagt atatttctcc agaaaatgcc ttggatagtc gtaaccgtca
     3001 atggaagatt tactcaagaa acttgatttc accaccaaac ttcctcgggg caaatgctca
     3061 tgtggaagac tcattagttg tagacggatg tttcgttgat ggaactgtta aacattctat
     3121 cctttcaaca ggcgcgcaag ttcgcgaagg agcggaagtc cttgattcag ttatcatgag
     3181 tggagctatc attggtcaag gagctaagat taaacgtgcc attattggtg aaggtgcgat
     3241 tatttctgac ggtgtcgaaa ttgatggaac agatgaagta caagttgtag gatataatga
     3301 agtagtgggg gtagcaacag atgaagattg ataaatattc tgccatttta ggaaatacag
     3361 ttggttttca caatatgtcg acattgacgg accaccgtcc agtagcaagt ttgccatttg
     3421 gtgggaaata tcgtttgatt gacttcccac tttcaagcct tgctaatgca ggtgttcgta
     3481 gtgtctttgg tattttccag caggataata tcagctcagt atttgaccat attcgttcag
     3541 gacgcgagtg gggcttatca acccttctta gccattacta tctaggaatt tacaataccc
     3601 gtgtagaaag tagtacagtt ggaaaagaat actaccaaca gcttcttact tatttgaaac
     3661 gttctggctc aaaccaaacg gttgccctca actgcgatgt tcttattaac attgatttga
     3721 accaagtttt ccacctacat agtacaacaa aagagcctat cactgtagtt tataaaaaac
     3781 tagctaagaa agatatttca gaagtaaatg caatcttgga tgtagatgaa acagaccatg
     3841 ttctttctca taaactcttt gatagcaagt caacagctga aacgttcaat atgtctacag
     3901 atatctttgt cgttgataca ccttggttga ttgaacactt ggaagaagaa gctaaaaaag
     3961 aacatccaga gaaattgcgc tatgttttac gggatttggc tgtaaaagag ggagctttcg
     4021 cctacgagta cacgggctat ctagccaata ttcactctgt taaatcttat tatcaagcga
     4081 atatcgatat gcttgaatca caaaaattct attctctttt ctcaccaaac caaaagattt
     4141 atacaaaggt caaaaacgaa gagccaactt actatgctaa tacatctaag gtaagcactt
     4201 ctcagtttgc ctctggtagt attattgaag gtcaagtagc taattctgtt ctatcacgta
     4261 atattcatgt ccataaggat agcttggtta aagatagcct gctcttccct cgtgttgtta
     4321 ttggagaagg ggctcaggtc gaatatgcta tcttggacaa aggggttgaa gttgagcctg
     4381 gtgttgtgat tcgaggaact gcagaacatc cagttgtggt taagaaaggt gctaaagtaa
     4441 cagaggatat tcattcatga aaattttatt tgtagcagca gagggtgcac ccttttcaaa
     4501 aacaggtggt ttgggagacg tcattggcgc tcttccaaaa tcactggtaa aagctgggca
     4561 cgaagttgca gtgattttac cctactatga tatggtagag gctaaatttg gaagtcagat
     4621 tgaagatgtg cttcattttg aggtgagcgt tggttggcgc agacagtatt gtggaattaa
     4681 gaaaacagta ttaaatggtg taaccttcta ctttattgac aatcaatatt atttcttccg
     4741 tggtcatgtt tacggtgatt ttgatgacgg agaacgcttt gcctttttcc aactggctgc
     4801 cattgaggct atggaaagga ttgactttat tcctgatctt ctccatgttc atgactacca
     4861 tacagctatg attcctttct tgttgaagga aaaataccgt tggattcaag cctatgagga
     4921 cattgaaaca gttttaacca ttcataattt agaattccaa ggacaatttt cagaaggaat
     4981 gttgggtgat ttgtttggag ttggctttga acgttacgct gatggcaccc ttcgatggaa
     5041 caactgtctg aactggatga aggcaggtat tctctatgcg aaccgtgttt caactgtttc
     5101 acctagctat gctcatgaaa ttatgactag tcagtttgga tgtaatttgg atcagattct
     5161 taaaatggag tctggtaaag tatctggtat cgtgaatggg attgatgctg atctttataa
     5221 tcctcagacg gatgctcttt tagactatca tttcaatcag gaagatttgt ctgggaaagc
     5281 caaaaataag gcaaaattgc aagaaagagt tggcttgcct gttagagcag acgttccact
     5341 ggtgggaatt gtttctcgtt tgacacgtca aaaaggtttt gatgtggtgg tcgaaagtct
     5401 tcaccatatc ttgcaagaag atgttcagat tgttcttttg ggaactggcg atccagcctt
     5461 tgaaggagct ttctcatggt ttgctcagat ttacccagac aagctatcaa caaatatcac
     5521 ttttgatgtc aaacttgctc aggaaatcta cgctgcttgt gacctcttcc tcatgccaag
     5581 tcgttttgaa ccgtgtggct tgtctcaaat gatggctatg cgttatggaa ccttgccatt
     5641 ggtccatgaa gttggaggct tgcgagatac agttcgcgct ttcaatccaa tcgaaggaag
     5701 cggtactggc tttagctttg acaatctatc tccttattgg ttaaattgga ctttccaaac
     5761 agcattggac ttgtatagaa accatccaga catttggaga aacctacaaa aacaagctat
     5821 ggagagtgac ttctcatggg atacagcctg caagtcatac cttgacttgt accatagttt
     5881 agttaattaa tagataaaat cgtatgatga cttcatacga tttttaggct gtttagagag
     5941 gagaactgat gtctcaagta aaaggcttgt gtgttttgga tgtagatgga accttaatcc
     6001 tagaagaagt gattgatctt ttagggagag aggcaggtca tgaggcggaa atttcgcaga
     6061 ttacaagtcg agcaatgcga ggagagttgg tctttgaaag cagtttaaga aaaagagtgt
     6121 ccttgttgga aggtcttcct attttggtct ttgataacgt cttcaactca attcatctat
     6181 cgctaaatgt cccagagttc atctctattc tccaaaagaa tggcatccta gttggtctgg
     6241 tgtctggtgg atttacacca atagttggag agattagcaa aatcccttgg tattgcctat
     6301 ttcactgcca accagcttga agtcaaagaa ggtcttttaa caggaaaatt agttggacaa
     6361 attataagtc cccaggtcaa aaaagaaact ctggaaaaat ggagaaagaa actaaaactt
     6421 tctaaagaaa gaacggtggc aatcggtgat ggggtcaata atctattaat gttgaagtcg
     6481 gcggagtgag gaatcgcctt ttgttccaaa gaaatgctca aaaaagaaat accacatcat
     6541 gttgacaaga gggatttttt agaagttctt cctttgattg actgtttaga atgagggaaa
     6601 atatgaagat tgtaattgca ccggattcgt ttaaggaaag cttgacagct caacaggtag
     6661 ctgaagcaat aaaaagaggc ttccaacaat cgatagcaga tgtagaatgt ctcctctgcc
     6721 ctgttggtga tgggggagaa ggtactgtag atgctatccg acattctctt gacctaaaag
     6781 aaaaatggat ccaagtgaca gacccttttg gacaaaaaga agccatgcgc tattttcaaa
     6841 aaggggaact ggcactattt gaagtagctg acttggttgg tcttggaaaa attccgctag
     6901 agaaacgaaa tccacttcaa atccaaactt gtggtattgg agagttgatt ctccatctca
     6961 tttctaaagg gattaaagat atttatatcg gtgttggtgg cacggccagt aatgatggag
     7021 gactggggat tgctgctggt ttaggttatc aattttatga tagggatgga aatgtcttgc
     7081 ctgcttccgg tcaatcctta ttaaacttag cttctgtttc aacagaaaat tgctataaaa
     7141 ttcctgaagg tgttcaaatt catattctag cagatgtcgt gagtccctta tgtggtcatc
     7201 aaggtgcgac ttacactttt ggcaatcaaa aaggtctaca tccgactatg tttgcagtcg
     7261 tagatcaggc gatccaagat ttttatgaaa aattctcacc tgcaacatta gaaattaaag
     7321 gagcaggagc aggtggaggc cttgctggtg gtttgtgtgc ctttgctcag gcaagtatcg
     7381 tgtctggaat tgatacctgc ttggacttaa tcaactttga taagaaagtt tcagatgctg
     7441 acttggttgt tgttggagaa ggaagacttg atagtcaaag ctttgctggg aaagcgccta
     7501 taggtgttgc aaaaagaacc cctgttggag ttcctgttat tgctatttgc ggtagtcttg
     7561 ctgaagattt acctccccta ccatttgaaa atatccaagc tgtcttttct attttggaga
     7621 aaagtgaacc tttagaagat agtttgaaaa atgccagtct ctatctggag cgcacggctg
     7681 ccaatattgg gcacttatta aatatgtgca agatttagct aaaccatttc ttccataagg
     7741 atgttttggc tggttcttcc tttttaactt cccaaatttt tggaaaagca agtcgaaggt
     7801 ctttttcttc tacttgaact ggtgcattgc tatgaataac caggccgaaa ggagaagtaa
     7861 tatgctcttc agatactatg gtggcttgac tatcagtttc ttttgcttct tttaagtaga
     7921 aaacttgctt atcaaattcg atagttggtg aaatcttcac aaatagtggc tctgcttttt
     7981 cctgaaggtt ttctaaaata aataaaaagc ctttttctaa ctgagggcta tttgctgtgt
     8041 caatatctac atatccaaga actctttcct caaaagtacc aagatagcgt ctttgctcat
     8101 ccggatttat ttttaaccca ccatgagctt tttcaagtaa ttgttttgat aaatctgtca
     8161 tgaaaacagt atatcataaa agttagaata aaacagacaa aagaaagcga ttactttata
     8221 aagttaagga aaagttgcac aaagataacg ttttttcttg aaaaaggagg ggttttaagg
     8281 tattatagag gtgtaaaaaa tttaactcat aaggagagta aaaaatgtca attattactg
     8341 atgtttacgc tcgcgaagtc ctagactcac gcggtaatcc aacacttgaa gtagaagttt
     8401 acactgaatc aggtgctttc ggacgtggta tggttccatc aggagcttct actggtgaac
     8461 acgaagcagt tgaacttcgc gacggtgaca aatctcgtta cggtggtctt ggtacacaaa
     8521 aagctgttga caacgtaaac aacatcattg ctgaagctat cattggctac gatgtacgtg
     8581 atcaacaagc tattgaccgt gctatgatcg cacttgacgg tactcctaac aaaggtaaat
     8641 tgggtgcgaa tgcaatcctc ggtgtgtcta tcgctgtagc tcgtgctgct gctgactacc
     8701 ttgaaatccc actttacagc tatcttggtg gattcaacac taaagttctt ccaactccaa
     8761 tgatgaacat catcaacggt ggttctcact ctgacgctcc aatcgctttc caagagttca
     8821 tgatcttgcc agttggtgcg ccaacattta aagaagccct tcgttacggt gctgaaatct
     8881 tccacgctct taagaaaatc cttaaatcac gtggtttgga aactgccgta ggtgacgaag
     8941 gtggattcgc tcctcgtttc gaaggaactg aagatggtgt tgaaactatc cttgctgcga
     9001 ttgaagctgc tggatatgta ccaggtaaag acgtatttat cggatttgac tgtgcttcat
     9061 cagaattcta cgataaagaa cgtaaagttt acgactacac taaatttgaa ggtgaaggtg
     9121 ctgctgttcg tacatctgca gaacaaatcg actaccttga agaattggtt aacaaatacc
     9181 caatcatcac tattgaagat ggtatggatg aaaatgactg ggatggttgg aaagctctta
     9241 ctgaacgtct tggtaagaaa gtacaacttg ttggtgacga cttcttcgta acaaacactg
     9301 actaccttgc acgtggtatc caagaaggtg ctgctaactc aatccttatc aaagttaacc
     9361 aaatcggtac tcttactgaa acttttgaag ctatcgaaat ggctaaagaa gctggttaca
     9421 ctgctgttgt atcacaccgt tcaggtgaaa ctgaagattc aacaatcgct gatattgcag
     9481 ttgcaactaa cgcaggacaa atcaagactg gttcactttc acgtacagac cgcatcgcta
     9541 aatacaacca attgcttcgt atcgaagacc aacttggtga agtagctgaa tatcgtggat
     9601 tgaaatcatt ctacaacctt aaaaaataaa atagttcagt gaactatttt atcccgaacc
     9661 atgaaattca aaagttcggc cgttgattta acaacgtttc tagcccctcg gattttatcc
     9721 gaagggctat ttttgtattt agaggacaaa aaagggacaa aactttttaa aaaatctttt
     9781 tcataacttt atccagtaca ttgattgctt catctttcat gttctttgtg acgtgggtgt
     9841 agatggaagt agtgacttca gagtcggaat gaccaaccct gtccgtgatt gtttttaaag
     9901 gaattttatt ggctctttgt caactgtagt gggttgaaga aaagctaagc ttgagaaagg
     9961 acaaattttg tcctttcttt tttgatattc agggcgataa aaatccgttt tttgaagttt
    10021 tcaaagtttc gaaaaccaaa ggcattgcgc ttgataagtt tgatgagatt attggtcgct
    10081 tccagtttgg cattagaata gtgtagttga agggcgttga caatcttttc tttatctttg
    10141 aggaaggttt taaagacagt ctgaaaaata ggatgaacct gcttaagatt gtcctcaata
    10201 agtccgaaaa atttctctgg ttccttattc tggaagtgaa acagcaagag ctgatagagc
    10261 tgatagtggt gtttcaagtc ttgtgaataa ctcaaaagct tgtttaaaat ctctttattg
    10321 gttaagtgca tacgaaaagt aggacgataa aatcacttat cactcagttt acggctatcc
    10381 tgttgaatga gtttccagta gcgcttgata gccttgtatt catgggattt tcgatgaaac
    10441 tgattcatga tttggacacg cacacgactc atagcacggc taagatgttg tacaatgtga
    10501 aagcgatcca acacgatttt agcacatggg aaaagttgtc tagctaagtc atagtaagga
    10561 ctaaacatat ccatagtaat gattttgacg cgacatcgga cggctctatc atatttaaga
    10621 aagtgatttc ggatgacagc ttgtgttctt cccttaagaa cagtgatgat attgagattg
    10681 ttaaaatctt gcgcaatgaa gctcatcttt ccttttgtaa aagcatactc atcccaagac
    10741 ataatctcag gaagacaaga aaaatcatgt ttaaagtgga agtcattgag ctttcgaatg
    10801 acagttgaag ttgagatgga aag
//
LOCUS       DAVHSY010000052        10741 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.053, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000052 DAVHSY010000000
VERSION     DAVHSY010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.053"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(104..1528)
                     /locus_tag="VVR43_001808"
     CDS             complement(104..1528)
                     /locus_tag="VVR43_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU6150123.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2072..4351)
                     /gene="pulA"
                     /locus_tag="VVR43_001809"
     CDS             complement(2072..4351)
                     /gene="pulA"
                     /locus_tag="VVR43_001809"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU6150124.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHFLVVVNAKSDPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4463..6421)
                     /gene="ligA"
                     /locus_tag="VVR43_001810"
     CDS             complement(4463..6421)
                     /gene="ligA"
                     /locus_tag="VVR43_001810"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU6150125.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6514..7692)
                     /locus_tag="VVR43_001811"
     CDS             complement(6514..7692)
                     /locus_tag="VVR43_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6150126.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7772..8635)
                     /locus_tag="VVR43_001812"
     CDS             complement(7772..8635)
                     /locus_tag="VVR43_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU6150127.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLDHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8638..10539)
                     /locus_tag="VVR43_001813"
     CDS             complement(8638..10539)
                     /locus_tag="VVR43_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6150128.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALLIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3224 a         2370 c         1912 g         3235 t
ORIGIN      
        1 gtttcaatct attataatac caaaaagttc gtattttttc tataattatt attattttat
       61 agcaaaaaat aaaaccagga aaacaatttc ctgattttac acgttatttc acatcaaaaa
      121 caatggattt gacatttgtc atcgcttcaa tgctatattt aattccttgc actccagctc
      181 cagaaccttt gacaccaagg aatgggaaat tatctggacc acgctgggtt ttattattaa
      241 tgtggactgt acctacttca agtttttcag caatttcaaa ggcttttttg aaatcatttg
      301 taaaaactga tgattgaagg ccgaattcag attcgttggc aaaggcaata gcctcctcta
      361 cactagccac acgaatgatt ggtaaaacag gaccaaatgg ctcttcccat gccactttca
      421 tatcttttgt aacttggtca aaaagcactg gccagaggag attgccctca cgtttgattg
      481 gtgtaagagc ctgagcctct ttttcttgtg catcctcaat caagccccaa atgaagtcgg
      541 ctgaagcatt gtcaataaca ggtgtaatat cagcattgtc aaatggatca ccaactgtta
      601 atttagaaac ttcttcctga agcaaagtag ctaatttatc tgctacactt tcgagaacaa
      661 tgacacgttt aatggccgtg caacgttgtc ctgagtagct aaaggctccc gcaacaattt
      721 gcttggcagc atgttccaaa tctgcatctt ctagtacaag agctgcatct ttcccaccaa
      781 gttccaacat gataggacgc ataccagcta aacgaccaat acgttctcca ataggagttg
      841 aacctgtaaa gttgatgaag ttgacttctt tgtgctcaat gatataatcc ccaatttctg
      901 aaccacgacc tgtaatggtg ttgaaaacac ctgccggaat ccctgcttct tcaaatgctt
      961 tagccaacaa gagtccagaa atggaacctt gtgttggtgg cttaaacatg accacattcc
     1021 ctgcaatcaa ggcaggtgca attttagaag cagataaatt aactggataa ttaaaaggag
     1081 caatcgctag cacgatacca actggttcac gacggacaac agccagtttg tttttacttg
     1141 ctgcctcaaa accaccacct tccattgctt gtccagtgat acggagacct tcctcagcag
     1201 cataacgaat caagtctgct gtacgcacta cttctccaat tgctgcttta atcccttttg
     1261 ctacttcttt ggcaaggata gtaccaattt tttccttatc gcgttctaaa atagctgctg
     1321 ttttatgcaa ataagccgca cgttcaattg ctgataaagc tcgccatgct ggcagggctg
     1381 cacgcgcagc ttgcatagcc tcatcagctt cagtctgagt catggctgga actgtaccca
     1441 attcttcttg attgattggt gagtaaatcg taatttcttg ttcagatgat ttccattttc
     1501 catttactaa attctgatat cttgtcaaat tcttgtcctc ctgaaaatga ttaagatata
     1561 ttttaccaaa ttttcagaaa atcacaaccc tttttgcaaa atttttgaga ttattttcac
     1621 aaacttgatt tttcaaagta tactcaataa aaataaaaaa aatccactac gtcaaggcga
     1681 ggctaatgtg gtttgaagaa attttcgaag agcgtgaatg agtatcatct atagtaaaat
     1741 aaaaaactga acaatttggt tggggacagc caaaccaatt tctcacaatg tttcagaaac
     1801 aagggtgtgc tactccaatt tcggcctact ataactgtca tagattgctg aaacaaagtc
     1861 taggtaaaag tcttcataat aaaaagacct cctatcaaat gttcaaaaac tttgatagga
     1921 ggtcttgttt cgtgaaaata tttatcaaat tttctataca agtgagctgt tagccaggtt
     1981 ctttctattc tttcaatttc aatgaatgga ttttttacca atactcataa ctgggaattt
     2041 ttctgtctaa aaatagcgag atagatggta tttataaaac actcaagaca gctagactaa
     2101 tatcatttaa aacattatct tcttttgagc gactgttggt taccaacata gctaaatttc
     2161 ctgcattttc aaattgatag gggtctgatt tagcattcac aaccaccaag aagtgttctt
     2221 tgccgtgaac ttcatagata aggtagccgc tatgttcaat cgcagaatgc acaaagacat
     2281 gatggtaaat ttcatcatag ctagagtaag aaaaggcacc agtttttgtc ttcaatcgga
     2341 tgacttgacg gataaactca atactgtctt gacgctcatt aatcaagttc cagttcactt
     2401 ggttcacact gtcaggagca ttatagctat tcatcgcacg ctctctatca tcatgggtta
     2461 actcaccatt ttcaccagtc gcaaccagtt tggtacgacc aaattcttga ccgatttcca
     2521 taaaggccat cccctgcatg agcagattca tggctgtggc agtttcgacc ttgcgcatga
     2581 tttgctctga actttggtct ggatgaaggg ttgccaataa atcgtgaaga ttgtaattgt
     2641 catgggcttc tacatagtta agcacctgat ttggatgtgt atagcttcct aattcacgac
     2701 ttcctaggat tgctttagct agaattggct ctgtcgcagc accactgaca aaacctgact
     2761 tgatagcacc ataaacttct ccccctttga cagcatcgcg ctgattgtca ttaaagaaac
     2821 caatatttgg catctggtag gcattgtcct tcttggcctt atcataaggg gcaagacctg
     2881 ttcccatatc ccatccttct ccatagagga taatgttgga gtcgatttca tccaagcttt
     2941 gacgaatcat ctgcatggtc ttgacatcat gaatccccat caagtcaaaa cggaagccgt
     3001 caatattata ttcctgcacc cagtatagaa gagaatcaat catatacttg cgaaacattt
     3061 cgtgttcact ggctgtttca tttccaacac ccgttccatt ctggaaggta ccatctggat
     3121 tcatacgata atagtaatca gggactgttg tttggaatgg tgcatcaaca actgagaagg
     3181 tatggttata gactacatcc ataatgactc caatacccgc atcgtgataa gcttgaacca
     3241 tcaccttcaa atcacgaatg acctgagctg gatcatctgg attagttgaa aaactagttt
     3301 ctggcgcgtt atagttttgt ggatcataac cccagttgta ggttacattt ccatcctcat
     3361 cgtattcttt atgacggtct gcaattggtt gcaattgaac ataattgtag cccagcttct
     3421 tgatgtaatc aaaagcagtt gactggccgt attggttaac tgttccagcc tgagcagcac
     3481 ccaagaaagt tcctcgaaga tgttcatcta cacccgatgt aggtgattta gtcaaatcac
     3541 gaatgtgcat ttcacagata actgccttac atggattttc caagcgccaa gtagcctccg
     3601 aaccgtgctt aacctcgaag ttttcaactt gcttttctac atggctcaga atagctgaac
     3661 gtttgccatc agggctggtc gcgattgtat aaggatcacg tgtcagtgtt tggtgatgag
     3721 ggaattggac ttgatactga taagtcttac ctaccaaatc ttcttcaaca tccaaactcc
     3781 agacaccgat tgtattgtcc ttatgattat aagagtagct attgcctctt ttcatctcaa
     3841 aagtcttcca aacgggtgca tcattagcag ctgattcata aacgacaact tgcacttctg
     3901 tcgctgtagg tgaccagaga gaaaaatgag cctgattgtc ctctacacgg caacccaatt
     3961 ctccttggta accccaatga tgatcaaaac tagcactgtt aatggcctta tcaaaggcaa
     4021 aaggattttg atttttatag aaaggactgg caatagcagg attttcagag taataaatcc
     4081 tatcatcgcc ttccaaaatc cagacctctg ttaatagggg atagtgatta aaacggatag
     4141 aatattcttt actagtttga cctgtatgaa ccacaaaatt caagctttct ataacatgtg
     4201 aacttgggtg ttcaaagcta aataaagctc caaaataatc ttctttgtag gttagcaaat
     4261 caattcgttg atcctgactt tttacaaagg agcaagtgtc atattctcca ttcttacgat
     4321 ggtaatgaat gcgcataggg tagttataca ttttttattt ttccttttta ctttgtttct
     4381 atttcactaa taaatttttg tcaatctcgt ctcaattaac agacatagtc atattctcta
     4441 aactctgttt ttaaacgatc cattacaaac tttctagcca tgcctcatct ctgacctgga
     4501 taccaagttc ttgtgctttt tgcagtttac ttccagcgtc tgcacctacc acgacgaggt
     4561 cggtcttttt agaaacacta cctgtcactt tggcacccag actttcgagt ttacttttag
     4621 cttctgagcg cttgagtcgt tccaattttc ctgtcaatac cacggtcaaa cctgacaagg
     4681 ccgcatccgc tactaccgtc tgtcctttat agtccagatt gaccccagtt tctttcaatt
     4741 ctctgagcag aatttcagag ccttctgtcg caaaataagt ctgaagactt ttggcaatca
     4801 cgccacctag actttcaata ctagccactt cctctgaatc tgcctgatac agattttcaa
     4861 ttgaatggaa atattgaagt aaaagctgac tagccttgct tccgacatga cgaattccca
     4921 aaccaaataa gagcttctcg gcagaatttt cctttgatgc ttggatagcc tgatacagtt
     4981 tagcagcgga cttttcctta accccctcta aaaggaggaa atcctcttct tgcaaacgat
     5041 aaatatccgc cacatccttg actaaattag cagcaaaaag cttctcaaca atagatggac
     5101 caaggcctgt aatattcata gcatcacgag aagcaaagtg aatcaagcct tccatgattt
     5161 gagcagggca acgcggattg atacaacgta gggccacttc atcttcaaag tgcaacaagt
     5221 cagagttaca acttggacag tttgtaggga tatctagttt ttcttcagaa acccgtttgg
     5281 actctaccac acgtaaaacg gcagggatga tgtcaccagc cttatataca atgaccgtat
     5341 cgtcttttcg gatatctttt tcagcaatat aatctacatt gtgcagggtc gcacggctaa
     5401 cagtcgtacc ggcaagttgt actggtgtta gattagcagt tggagttaca acaccggtac
     5461 ggccaactgt ccagtcaact gataagagtt gagcttcttt ttcttcagca gggaacttgt
     5521 aggctactgc ccactttgga gccttaacgg taaaaccaag ttcttcttga cttgctaggt
     5581 cgttgacctt gattaccact ccatcaatat cgtaaggcag attttcccgt tcctgtccta
     5641 cttcttggat aaaattccag atttcatcta tgttttcagc caagattcgc ttaggattga
     5701 ccacaaaacc tagttgttct aggtacttca aacccttttc ttggctatca cgagttgaag
     5761 ggctggcttc ttgatagaga aacgttgcaa gattacgctt ggcaactact gctgtatcca
     5821 actgacgcag agttcctgct gccgcattac gaggattagc aaattcaggc tctccatttt
     5881 cttggcgcac ttggttaact tggtcaaagg aagcgcgtgg catgtaacat tccccacgaa
     5941 ctgtgatatc tagttcttct ggcaaagtca aagggatgtc cttaacacgc ttgaggtttt
     6001 ctgtgatatt ttcaccaatt gaaccatctc cacgtgttac cccagcaacc aaaatcccct
     6061 tttcataagt cagcgagata gataagccat cgattttcag ctcacaaata taggtcggat
     6121 gagccacttc cttacgaaca cgcgcatcaa aagcatctag ctcctcacgt gaaaaagcat
     6181 cctgcaaact ataaagagga tactgatgac tgtatttttc aaaaccatct aaaaccttgc
     6241 caccaacacg atgagtcgga ctgtctgcta gcacttgctc tggataagca gtttctaact
     6301 cgaccaactc acggtaaagg cggtcatact cactgtctga aaccgaggga ttatcgctgg
     6361 tatagtactc agtcgcatag cgattgagca aagcgactaa ctcattcatt cttttattca
     6421 taagaccatt ttaccataaa acaagccctc ctcacaaacg agaaggacgg aaaaaacact
     6481 tagtttgaaa ttatttttga aactcaagca accttatatc aatttttcaa aatgagttcg
     6541 aacataaata aacgatatac aagacaagat gataacacca cttccaatta tcaggaaaga
     6601 agagagatgt acacttggca agactgtcat aaatcctttt gcaataggca taaatagaat
     6661 agctaaggta aaaattgtac tcagtactct cccaagaaat tcgctctcaa ccttggtttg
     6721 tacttgagta aaaaagtgaa tattaaaaat cgtcataaac aattcacaaa ctaaatttcc
     6781 agaaaaggaa agaaaagttg gaagtggtaa tcccatcata aaaactccga cacctgtcaa
     6841 agccagtaaa atcaaaagat tataaatatt agctttaatt ttactagcta gaagagcccc
     6901 aatgatggaa ccaatagccc ccatagttaa aatacttgca taggctcctt ctgacccgta
     6961 aagctgattc gaaaagggaa gtagaaattc aaaagctgca aaaaagaaat taacgctgga
     7021 agctaccagc aaaaggaaga aaatttcttg ctgatgccag atatagtgta acccatcctt
     7081 gatatctaca aaaatatctc tcccagtaaa agcctttttc tcttgaactt ttgcttcctc
     7141 ttttggaagg aaagccacta gaacaaaagc aatgaaaaaa gtcagcgagt ctagcagtag
     7201 cgtcatatgg agacttgcaa actgtaaaac aaggaaggaa agaacaggag agctaacacc
     7261 tacaacctgc aaaaccagct ctaggcgaga attatagatc acaatctcat ctttctccac
     7321 cacttcagtt atgatagctt tattggctgt gcgagaaaag gcaaaagcaa tagcctgcac
     7381 aatgttagca acaatcaaag cgccaatcat ccagctatca ttccttatga aagaaatagc
     7441 cagacaaaga atcccacaaa caagatctgc cgtcattaaa atcttacgac gagaaaaacg
     7501 gtctgaaata actccgccaa agggattgac gagaatagat gtgacgagct cagaaatctg
     7561 atacattcct aaaactgtct gtcctatagt ccccatggaa gccaaccaga cactatttcc
     7621 ataatcatag agcatatttc ccattttatt gatagcccca cggctaatca actgcactgc
     7681 atagcgattc atattaaagc tcctctcaaa ttttgaaact attgtatcaa aaccgaaagg
     7741 agctttttat tttttccctt atttgggaaa attaactttt gacaaatttt tcgtagtgtt
     7801 cctgataata ggctacttgc tctggaagac ctaacacatc aaaaatatgc atggcctctt
     7861 gcatctgctt acagccttct ttacactgtc ctttttgata taaggcaaaa ccttttaaat
     7921 aatggaaaac attacgctca taaagcttaa tacctttgtc aataatcttc tctgtataag
     7981 cctcaaaata gttggcatta taaaaagaag aatgatctaa acaatgctgg taacaattga
     8041 gggccaaaat caacactaat ctcttatggc gactaatctc ttggtaaaat tcctccctct
     8101 ccataacttc tctaccaatc cgagtgacat agtctacatc gtagaaacta tagaggttac
     8161 cgaaaagaat caactcatac atggtccatt cttctgtttt gaagagataa tctgctacct
     8221 tatccaaatc atcctgcttc atatcataac tcgcatctct ttgacaaatc agaccttgta
     8281 gcaaaatcca gttcagctca aaataaaggg gagtcgtcga actcttagac ttttcaagtt
     8341 gttctctttg aagcttttga aaacctgcaa tatcgtttga atagtaaagt gggataatct
     8401 gtgccatcat agacacatgt tcatgattat gaaaattcct tgccttatcc atgaaatttt
     8461 cgattgttac atgaatgtta tccaaaatct caaagaaacg ggagactgcc aggtcagact
     8521 ccccaagctc aaagcgagat aactgagagg tagagcagga ttcgcctgct gcttccttta
     8581 aagaataatt tccacttgtt cgaaattcac gaaatacttt tccaagatgt tccatcttta
     8641 cacctgatct gataattctt cccactcaag catagcttct tcctgacgat ggctgatttt
     8701 gtccagctca gcctgtaatt ccatgagttt gtcggcatcg tttgtttcca acatttgttc
     8761 agaaatggct tggctttgac tttctagctc ttcaatttca gcttctagac tttcgatttg
     8821 tcgcatgagt ttgcgaactt ctttttgact ttctttctgg gcctgatagt cattgactgg
     8881 acttgcttcc tttgcttgat tgctagttga agcttcctca gtctgactca tttctgctgt
     8941 tgctttcttc tcaacatagt agtcgtaatc tccaaggtag agagttgaac cattctcaga
     9001 caattccaaa acatgagttg ccacacgatt gataaagtaa cgatcatgac tgacaaaaag
     9061 caaggtacca tcaaagtcaa tcaaggcatt ttctagcact tccttactat caatatccaa
     9121 gtggttggtc ggctcatcca gaatcaaaaa gttattgttt tccatagaca atttagctaa
     9181 aagcaaacga gctttttcgc caccagatag catgccgact gattttttaa catcatctcc
     9241 tgagaaaagg aaggctccaa gacggttgcg gatttcaact tctggtgtca gtttgaaatc
     9301 attccagagt tcatccagca ccgtattact tggtgtcagc ttgctttggg tttggtcata
     9361 gtaacccacc tcaacattag cgccaaagcg cttttctccc ttgataaaag gaatctggtc
     9421 cacaatagac ttgataaagg ttgacttgcc gataccattt ggaccaacga tagcgacagc
     9481 attcatctta cgaagatcta ggttgatagg ttgtgacaag acttccccgt cataaccaat
     9541 agcagtattt tcaacagtca aaacaacatt gcccgacgtt ttttcagact ggaaggtcat
     9601 gttggctgct ttcttgccag cttcaggctt gtccaaacgc tccatttttt ctagttgttt
     9661 acggcgagat tgagcacgtt tagtcgttga agcacgaact agattgcgat tgacaaagtc
     9721 ttccagagca gcgatttcct tctgttgctt ttcatagttt tttgcctcag tagctagctt
     9781 ttgctccttc aattcgacaa aacgagagta attccccaca tagcgatcca aggaatgctt
     9841 ggtcaaatct agcgtaattg tcgcaacctt gtccaagaaa taacggtcgt ggctgacgat
     9901 aaggagggca ccgctatagt ttaccaagta attctctagc caggcgatgg tttcaatatc
     9961 caagtggtta gttggctcgt ccaagaccaa gagattgggc ttttcaagga gcattttggc
    10021 aagtgccaaa cgagtatttt gaccaccaga aagctcagca attttcatct gccacataga
    10081 ctcgtcaaac ttgaatccat tcaaaatcgc tcgaatatca gcttcatagg taaagccacc
    10141 tgcttggcga aaattctcag ataagcggtc ataatctgac atcagtttat ccaaatcctc
    10201 accagacttt tcacccatct ccagctccat ctgacgcagt tgtctctccg tccgacgcaa
    10261 attattaaag acatgaagca tttcatcgta gatggtattt tcagactcaa aacggctatc
    10321 ttgggctagg taagacagag aaatatcttt tttcttattg atttctccgc tagttggctc
    10381 ctcttctcca actaaaatct tcaaaagagt agacttacct gcaccatttt tcccaacaag
    10441 ggcaatccga tctcgttcat caacctgcag gttgatatta tcgaaaagaa cctctcctgc
    10501 aaaagaacgt tcaattttat tagcttgtaa aataatcata agagtagtat agcatgtttc
    10561 cctaaggcat tcaagataat cgtaagtctt ttagtacaac ttttataaca taaaataaac
    10621 taaattatgt atattttata ttagattctt cactatcttg ttggattttc taaccagcta
    10681 atcttgtttc aaatagttat cgcacaagcc tattatttaa ttcttttcat tatttacgta
    10741 c
//
LOCUS       DAVHSY010000053        10511 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.054, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000053 DAVHSY010000000
VERSION     DAVHSY010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10511
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.054"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..410
                     /locus_tag="VVR43_001814"
     CDS             <1..410
                     /locus_tag="VVR43_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6150129.1"
                     /translation="FDQVASLLEEREIVTPTYREALITREKSFPTGLDMEFLGKDLPN
                     VAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGKEVEVSLLFFIINNSSSSQTNILA
                     QLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            448..750
                     /locus_tag="VVR43_001815"
     CDS             448..750
                     /locus_tag="VVR43_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6150130.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAKQNMV"
     gene            758..1561
                     /locus_tag="VVR43_001816"
                     /pseudo
     CDS             758..1561
                     /locus_tag="VVR43_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1598..2074
                     /locus_tag="VVR43_001817"
     CDS             1598..2074
                     /locus_tag="VVR43_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU6150131.1"
                     /translation="MPYFIGGHPGFNCPLLDDGVYEDYYLESEKEETCSVPRPFPETG
                     MLDFQDRSPWLEGQKEIDLSYDLFSKDAVTLDELQSRTIALRSLKHDKGLKVHFAEFP
                     NLIIWSTLNKGPFITFEPWSGLSTFLEEGEHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            2231..2656
                     /gene="lacA"
                     /locus_tag="VVR43_001818"
     CDS             2231..2656
                     /gene="lacA"
                     /locus_tag="VVR43_001818"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU6150132.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFIVATKIKGMVAAEVSDERSAYMTRSHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2687..3202
                     /gene="lacB"
                     /locus_tag="VVR43_001819"
     CDS             2687..3202
                     /gene="lacB"
                     /locus_tag="VVR43_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU6150133.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHVETHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            3213..4142
                     /locus_tag="VVR43_001820"
     CDS             3213..4142
                     /locus_tag="VVR43_001820"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU6150134.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGNLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            4144..5124
                     /gene="lacD"
                     /locus_tag="VVR43_001821"
     CDS             4144..5124
                     /gene="lacD"
                     /locus_tag="VVR43_001821"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU6150135.1"
                     /translation="MALTEQKRARLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            5358..6194
                     /locus_tag="VVR43_001822"
     CDS             5358..6194
                     /locus_tag="VVR43_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU6150136.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGFKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            6230..6547
                     /locus_tag="VVR43_001823"
     CDS             6230..6547
                     /locus_tag="VVR43_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6150137.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6547..8238
                     /locus_tag="VVR43_001824"
     CDS             6547..8238
                     /locus_tag="VVR43_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU6150138.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARYFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FNLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALVFVQEQFD"
     gene            8453..9859
                     /gene="lacG"
                     /locus_tag="VVR43_001825"
     CDS             8453..9859
                     /gene="lacG"
                     /locus_tag="VVR43_001825"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU6150139.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDHENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLNL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLIDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9902..10159
                     /locus_tag="VVR43_001826"
     CDS             9902..10159
                     /locus_tag="VVR43_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU6150140.1"
                     /translation="MFKDFIQSIYEKVYIINFEKYSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDELEEFKNLFLNFINPEEWDTISSDSDFMPFQQS"
BASE COUNT         3342 a         1880 c         2160 g         3129 t
ORIGIN      
        1 tctttgatca ggtagcaagc ttgttggaag aacgagaaat tgtcactcct acttatcgtg
       61 aagccttgat cacgcgtgaa aagtcatttc caactggttt agatatggaa tttctaggaa
      121 aggacttgcc aaatgtagcg attcctcaca cagatattgt tcacaatctg gctgaaaaag
      181 ttgtggtcgt tcgattagag aaaccggtga ctttccataa tatgattgcg ccaggtaagg
      241 aagtagaagt atccttgctc ttctttatca tcaataattc aagttcaagt caaacgaaca
      301 ttcttgctca gttgatggac ttcttcacag gaaatggtca tcttgaagac ctatcaaaaa
      361 tttctgaacc agaaaaactt tatgcttaca ttgctgaagc aaccgcttaa tcttgtctat
      421 taaaaaataa aatcggagga aatccaaatg attaaaattc ttgctgcctg cggtgcaggt
      481 gttaactcaa gtcaccaaat taaaagtgct ctagaagaag aactttcaaa ccgtggttat
      541 gatgttcact gtgatgcagt catggtgaaa gatgtaaacg aagaccttat gaaaggttac
      601 gatatcttta caccaatcgc tgcaacagac cttggttttg aaccaggtat cccagttatc
      661 gaagctgggc caatcttatt ctgtatccca gcaatgagcg ttccagtatt tgacaatatt
      721 agacttcctg cgaaacaaaa tatggtatag tagttctatg aatgatgaag caagtaaaca
      781 actaactgat gcacgattta agcgtcttgt tggtgttcag cgtaccactt ttgaagagat
      841 gttagctgta ttaaaaacag cttatcaact taaacacgca aaaggtggac gaaaacctaa
      901 attaagccta gaagaccttc ttatggccac tcttcaatag tgcgagaata tcgaacttat
      961 gaacaaattg cggctgattt tggtattcac gaaagcaact ttatccgtcg gagccaatgg
     1021 gttgaagtaa ctcttgttca aagtggtgtt acggtttcaa gaactcctct cagctctgag
     1081 gacacggtaa tgattgatac gacggaagta caaatcaatc gccctaaaaa aagaattagc
     1141 gaattattct ggtaaaaaga aatgccacgc tatgaaggct caagcgattg tcacaagtca
     1201 agggagaatt gtttctttgg atatcactgt gaactattgt catgatatga agttgttcaa
     1261 aatgagttgc agaaatatcg gacaagctgg taaaatcttg gctgacagtg gttatcaagg
     1321 gctcatgaag atatatcctc aagtacaaac tccacgtaaa tccagcaaac tcaagtcgct
     1381 aatagctgaa gataaagcct ataaccatgc gctatctaag gagagaagca aggttgagaa
     1441 catctttgcc aaagtaaaaa cgtttaaaat gttttcaaca acctatcgaa atcatcgtaa
     1501 acgcttcgga ttacgaatga atttgagtgc tggtattatc aatcatgaac taggattcta
     1561 gttttgcagg aagtctaata aagaaactag caaggtcatg ccttacttta ttggtggaca
     1621 tccaggattt aattgtcctc tacttgatga tggagtctat gaagattatt atctagagtc
     1681 tgagaaagaa gagacttgct ctgttccacg tcctttccca gaaacaggta tgttggattt
     1741 ccaagataga agtccatggc tagagggaca aaaagaaata gatcttagtt atgatctttt
     1801 cagcaaagat gcagtgactt tggatgaatt gcaatctcga acaattgccc ttcgttctct
     1861 taaacatgat aagggattga aagtgcattt tgcagaattt ccaaacctca tcatctggtc
     1921 aactttgaac aagggacctt tcattacctt tgaaccatgg tctggcttgt caacattcct
     1981 tgaagaagga gaacatttag aagataagaa gaatgtttgt ctcttagaag ccaatcaggt
     2041 tgaagaatta gggtttgaga tagaagtttt ataaaaaagt aaaaaataaa taacaaaaac
     2101 aaacacaaac tattgacttc ttcaaacaat agtagtatat tatgtttgtg aggactaatt
     2161 gactgttttt taaagacagc caatacactg ctggaatcca gcatagaaaa aataaaaagg
     2221 agtatacaat atgtctattg ttatcggtgc agatgctgca ggtttgagat tgaaagaagt
     2281 tgtgaaagac ttcttagaaa aagaaaactt ccaccttgtg gatgttacag ctgaaggtca
     2341 agactttgtt gatgtgactc tcgctgttgc tgcagaagta aacaaagaag aacaaaacct
     2401 tggtatcgtg attgatgctt atggagctgg tccatttata gttgcaacta agatcaaagg
     2461 aatggttgct gcagaagtat ctgacgaacg ttcagcttat atgactcgta gccacaacaa
     2521 ctcacgtatg atcactatgg gggcacaact tgttggtgat gaattggcta aaaacatcgc
     2581 taaaggattt gttaatggta aatacgacgg tggacgtcat caaatccggg ttgacatgtt
     2641 gaacaaaatg ggctaattag attacagtaa gaaaggtaag ttaaaaatga gaattgcaat
     2701 tggatgcgac cacatcgtaa cagatgaaaa aatggcggtt tcagaatttt tgaaatcaaa
     2761 aggatatgaa gtcattgact ttggtacata tgaccataca cggactcact acccaatctt
     2821 tggtaaaaaa gtaggggaag ctgtaactag cggccaagct gatcttggag tatgtatctg
     2881 tggtactggt gttggtatca acaacgctgt aaataaagtt ccaggtgttc gctctgcctt
     2941 ggttcgtgat atgacaacag ccctttatgc taaagaacaa ttgaacgcca acgttatcgg
     3001 ttttggtggt aagattactg gtgaattgct catgtgcgat atcatcgaag ctttcatcca
     3061 tgctgaatac aaaccatctg aagaaaacaa aaaattgatt gcgaaaattg aacatgttga
     3121 aacacacaat gctcaacaaa cagatgcaaa cttcttcact gaattccttg aaaaatggga
     3181 tcgcggagaa taccacgact aagaggtgac ctatgatttt aacagtcaca atgaacccat
     3241 ccattgatat ttcctatccc ttggatgagt tgaagattga tactgtcaat cgtgtggtag
     3301 atgtaaccaa aacggctggt ggtaaagggc tcaatgttac acgcgtactt tcagaatttg
     3361 gcgattctgt tcttgctact ggtttagtag gtggcaacct tggtgagttt ttggttgaac
     3421 atatcgataa tcaagtaaag aaagatttct tctcaattca gggagaaact cgtaactgta
     3481 tcgctattct ccacggagac aaccaaacag aagttcttga aaaaggtcct gaagtattgg
     3541 aacaggaagg tcaagacttt ttggaacatt tcaaaaaact cttggagtca gttgaagtag
     3601 tggccatctc aggtagtctg ccagctggcc ttccagttga ttactatgcg agcttggtag
     3661 aacttgctaa tcaagctggc aagcctgtag tcttggactg ctcaggtgca gcacttcagg
     3721 ctgttcttga atcaccccat aaaccaacag tcatcaaacc aaataatgaa gaattgtctc
     3781 agcttcttgg aagagaagtt tctgaggatt tggatgaatt aaaagaagta cttcaagaac
     3841 ctttgtttgc agggattgaa tggattatcg tttcacttgg tgccaacggt acttttgcca
     3901 aacatggtga cactttctac aaggtagata ttcctagaat tcaggtggta aatcctgttg
     3961 gatctggaga ctctactgtg gcaggaattt cttcaggact tcttcacaaa gaatcggatg
     4021 cagaattact catcaaggca aatgtccttg gtatgctcaa tgctcaagaa aaaatgactg
     4081 gtcatgtcaa catggccaac tatcaagttc tatatgatca attaatagta aaagaggtat
     4141 aaaatggctt taacagaaca aaaacgtgca cgcttagaaa aactttctga tgaaaatggt
     4201 atcatctcag ctcttgcatt tgaccaacgt ggtgctttga aacgcctcat ggctcaacac
     4261 caaacagaag aaccaactgt ggctcaaatg gaagaactga aagtcttggt agcagatgaa
     4321 ttgactaaat acgcttcatc aatgcttctt gaccctgagt atggacttcc agcaactaaa
     4381 gctcttgatg aaaaagctgg tcttctcctt gcttatgaaa aaacaggtta tgacacaaca
     4441 agtacaaaac gcttgccaga ctgcttggat gtttggtctg caaaacgtat taaagaagag
     4501 ggtgcagatg cagttaaatt cttgctttac tatgatgtag atagttcaga cgaactcaac
     4561 caagaaaaac aagcttatat cgagcgtatc ggttctgagt gtgtggctga agatatccca
     4621 ttcttccttg aaatccttgc ttacgatgaa aaaattgcag acgcaggttc tgtagaatat
     4681 gcgaaagtaa aaccacacaa agttatcggt gctatgaaag tcttttcaga cccacgcttt
     4741 aacattgatg tcttgaaagt tgaagttcct gttaacatta aatatgttga aggcttcgct
     4801 gaaggtgaag tggtttacac acgtgaagaa gcagcagcct tcttcaaagc gcaagatgaa
     4861 gcaacgaact tgccatacat ttacttgagt gctggtgtat cagctaaact cttccaagat
     4921 actcttgtat ttgctcatga atcaggtgca aactttaacg gagttctttg tggccgtgct
     4981 acatgggcag gatcagttga agcttacatc aaagatggtg aagcagcagc tcgcgaatgg
     5041 cttcgcacaa ctggatttga aaacattgat gagctcaata aagttcttca aacaacagcg
     5101 acttcatgga aagaacgtgt gtaagaaagt cctcctagtt taggaacatg aatctaaaaa
     5161 aatttaaaaa aagttgtatg taaaggttta caaaataact tacttgtgct atacttaaat
     5221 cacaagttaa tacaaggtga gtgttactaa gtaatattag gcatgatcac aggtgaatta
     5281 gaaatcagct gattttctag ttcatttgtg gtcatttttt gtactcatat acttttaaga
     5341 tataaaagga ggttgacatg tatcgaattc taaatccaat gaatcacaat gtctcgcttg
     5401 tcagaaatga taagggagaa gaggtgattg taattggtaa ggggattgca ttcggaaaga
     5461 agaaggggga tttgattgct gaaaatcagg ttgagaaaat ctttcggatg aagaccgaag
     5521 agtccagaga aaactttatg gctcttctca aagatgttcc gcttgatttt atcacagtga
     5581 cctatgaaat cattgataag ctatcaaaga aatatcatta tccgattcaa gagtatctct
     5641 atgtaacctt gacagatcat atttactgtt cttatcaagc tctaactcaa ggaaggtaca
     5701 aggatagtaa tctgccagat atttccgcta agtatcctgt cgcttttcaa atcgcaaatg
     5761 aagcttttga aatttaccgt cagaagctag cagatcattt tcctgaggac gaaattattc
     5821 ggattgctta tcatttcatt aatgctgaag gtgaaaatga agtggaactt gtggagtcga
     5881 ttgataagag gaaagaaatt ctcaggaatg ttgaagaagt tttaacggac tatgcaattc
     5941 aacgaactaa aaagaataac catttctatg atcgctttat gatccatttg aattatttct
     6001 tggattattt agacagatct agagatgata accaatcact tctggatatg gaagatcata
     6061 ttaaacaatc ctatccaaaa gccttcgaga ttggtttcaa gatctatgat gtgattacgc
     6121 aacatacggg tcttgatttg tataaaagtg aacgagttta tctagttcta catatccaac
     6181 gtttattgtc ataaaaattt atttaaaact atataaggag aattctatca tgaatagaga
     6241 agaagtaaca ttgttaggtt ttgaaatcgt agcctatgct ggcgatgctc gttcaaaact
     6301 attggaagcc ttgaaggctg ctgaagctgg tgattttgaa aaagcggacg ctctggtaga
     6361 ggaagctggt agctgtattg cagaggctca ccacgcgcaa acaagtctat tgactaagga
     6421 agcttcaggt gaggacttgg cttatagtgt aaccatgatg catggccaag accacttaat
     6481 gacaactatc ttgttaaaag atttgatgca tcatttaatt gaactctaca agagaggagt
     6541 taaataatga ataaactaat tgcatttatc gagaaaggaa agcctttctt tgaaaaacta
     6601 tctcgtaata tctatcttcg tgctattcgt gatggtttca ttgcaggtat gcctgttatt
     6661 ctcttctcaa gtatctttat cttgattgcc tttgtaccaa actcatgggg ctttaaatgg
     6721 tctgatgaag ttgtagcctt tctgatgaaa ccttatagct attctatggg tattctggct
     6781 ctcttggtag ctggtacaac agctaagtca ttgactgact cagtaaaccg gagcatggaa
     6841 aaaaccaatc aaatcaacta tatgtcaaca ttgttggcag caattgttgg tttgttgatg
     6901 ttggcagctg atcctatcga aagtggtcta gctactggat tcttggggac aaaaggtttg
     6961 ctttcagcct tccttgctgc ctttgttact gtagccatct ataaggtttg tgttaagaac
     7021 aacgtcacta ttcgtatgcc tgacgaagtt ccaccaaata tctcacaagt ctttaaagat
     7081 gtgattccat tcactctatc tgttgtttct ctttatgctc ttgacttatt agcacgttat
     7141 tttgttggtt ctagtgtggc agaatcaatc ggtaaattct tcgcaccact cttctcagca
     7201 gcagacggat accttggtat taccattatc tttggtgcct ttgccttctt ctggtttgtt
     7261 gggattcatg gtccatctat cgttgaacca gctatcgcag ctattaccta tgccaatgcc
     7321 gaagtcaact tgaaccttct ccaacaaggg atgcatgcag acaagattct tacttctggt
     7381 acacaaatgt ttatcgttac catgggtggt acaggtgcga cattggtcgt tccatttatg
     7441 ttcatgtggt tgacaaaatc gaaacgtaac cgtgcaatcg gacgtgcttc agtagttcct
     7501 accttcttcg gtgtaaatga accaatcttg tttggtgcac ctcttgtttt gaatccaatc
     7561 ttcttcattc catttatctt tgctccaatt gcaaacgtat ggattttcaa attctttatt
     7621 gaaactcttg gaatgaactc attcactgct aatctaccat ggacaactcc agctccacta
     7681 ggtctagttc ttggaactaa cttccaagtg ctatcattca ttcttgctgc ccttctaatt
     7741 gtggttgacg tagttattta ttacccattc cttaaagtct atgatgaaca aattcttgaa
     7801 gaagaacgtt caggtaagtc taatgatgaa ttgaaagaaa aagttgctgc aaacttcaac
     7861 actgcaaaag cggatgctat tcttgaaaaa gcgggtgtcg atgcagcaca aaataccatc
     7921 actgaagaaa caaatgtcct cgttctctgt gctggtggag gtacaagtgg actccttgca
     7981 aatgctttga ataaggcagc agcagaatac aatgtccctg tgaaagcagc agcaggcggc
     8041 tatggtgctc accgtgaaat gttaccagag tttaatctag ttatccttgc ccctcaagtt
     8101 gcttcaaact ttgaagatat gaaggcagaa acagataagc tcggtattaa acttgctaag
     8161 acagaaggcg ctcaatacat caaattaact cgtgatggaa aaggtgccct agtattcgta
     8221 caagagcaat tcgattaagg ctaggaactg tgaaacagtc tcccatcgtt acggaaatcg
     8281 ctatggcgaa tttcctaatc gccttattaa ttcgtcggta aaaagatatc gtttttacct
     8341 cctcatgtca caattcagtg acttggtaca agaagtgaga tggagaagca tggctcactg
     8401 actcctctcc tctcactttt actttattta aatcaagaaa taggtgaaaa aaatgacaaa
     8461 aacacttcca aaagacttta ttttcggtgg cgcaacagct gcttatcaag cagaaggtgc
     8521 tacacatact gatggtaaag gaccagtagc gtgggataaa tatcttgaag ataactactg
     8581 gtacactgca gaaccagcca gtgattttta caatcgatat ccagttgacc tcaagctagc
     8641 agaagagtat ggtgtcaatg gcattcgaat ttctattgcc tggtcacgta ttttcccgac
     8701 tggttatggt caagtaaatg ctaaaggtgt tgagttttat cataatctat ttgcggagtg
     8761 ccacaaacgt catgttgagc cctttgtaac tcttcatcac tttgacacgc cagaagctct
     8821 ccactcaaat ggcgacttct taaaccgtga aaacattgaa cactttgtag actacgcggc
     8881 tttctgtttt gaagaatttc cagaagtaaa ctattggaca accttcaatg aaattggacc
     8941 aatcggtgat ggtcaatatt tagttggtaa attccctcca ggaattcagt acgaccttgc
     9001 caaagtcttc caatcgcacc acaatatgat ggtgtctcat gcacgcgcgg taaaattgta
     9061 caaagagaaa ggctataaag gggaaattgg tgttgttcac gccctgccta ctaaatatcc
     9121 tctagatcat gaaaatccag cagatgttcg tgcagctgag ttggaagata tcatccacaa
     9181 taaattcatc ttagacgcaa cttatctagg tcgctattca gctgaaacca tggaaggtgt
     9241 caaccatatc ttatcagtca atggtggtag tttgaatctt cgtgaagaag attttacagc
     9301 attagaagct gcaaaagact tgaatgattt cctaggaatc aactactata tgagtgactg
     9361 gatggaagcc tttgatggag aaactgaaat tatccataat ggtaaaggtg aaaaaggaag
     9421 ctctaagtat caaatcaaag gtattggtcg tcgtgtagct cctgactatg tatcacgcac
     9481 ggattgggat tggattatct accctcaagg tttgtatgac caaatcatgc gtgtgaagaa
     9541 agattatcct aactacaaga aaatttatat cactgaaaat ggtctcggct ataaagatga
     9601 gttcgttgat aacactgttt acgatgatgg tcgtattgat tacgtgaaac aacacttgga
     9661 gatcttgtct gatgcgattg cagatggagc taatgtaaaa ggttacttca tttggtcatt
     9721 aatagatgtc ttctcatggt caaacggtta tgagaaacgt tatggtctct tctacgtaga
     9781 ttttgaaact caagaacgtt atcctaagaa atcagctcac tggtacaaaa aagtagcgga
     9841 aactcagatt atagactagt agaattagtc attagatata gaattttagt gagtcaaaaa
     9901 gatgttcaaa gattttatcc aatctattta tgaaaaagtt tatattataa atttcgaaaa
     9961 atactctcaa ataccgtgtt tgacgagtga agaattgaaa agtcttggaa aatggtatgt
    10021 ctcgactggt aaagaatgga tttgtcattc agatgatgag ctggaagaat ttaaaaatct
    10081 atttttaaat tttatcaatc ctgaagaatg ggatactatc tcctctgatt cagattttat
    10141 gccgtttcaa caatcgtaac caatttctca aaaaagttaa atcttatatt tagtactctg
    10201 taaaactctt atctaatcac gttgcttata ctcaatgaaa atcaaagagc aactttaaac
    10261 taggaagcga gtcgcagatt tctcaatgta tagctttgag gaattgggca aaaagtcttt
    10321 gatatagaaa aacgcatagt atcaggtgtt tcaacacctg atactatgcg ttttattgtg
    10381 ggaagatgta ctttttttct tctgaaattg agttgttacc caggctcttt cagtttatta
    10441 aggcttgatg actttaatgt gtttagatag cttaaaaagg attgaatcac ttagtttaga
    10501 atctgaaaca a
//
LOCUS       DAVHSY010000054         9881 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.055, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000054 DAVHSY010000000
VERSION     DAVHSY010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.055"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..321
                     /locus_tag="VVR43_001827"
     CDS             <1..321
                     /locus_tag="VVR43_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6150141.1"
                     /translation="EVKPQLEKPKPEVKPQLEKPKPEVKPQPEKPKPDNSKPQADDKK
                     PSTTNNLSKDKQPSNQASTNEKATNKPKKSLPSTGSISNLALEIAGLLTLAGATILAK
                     KRMK"
     gene            complement(540..1520)
                     /gene="dusB"
                     /locus_tag="VVR43_001828"
     CDS             complement(540..1520)
                     /gene="dusB"
                     /locus_tag="VVR43_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU6150142.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKGPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKV"
     gene            complement(1507..2379)
                     /gene="hslO"
                     /locus_tag="VVR43_001829"
     CDS             complement(1507..2379)
                     /gene="hslO"
                     /locus_tag="VVR43_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU6150143.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2544..3971
                     /locus_tag="VVR43_001830"
     CDS             2544..3971
                     /locus_tag="VVR43_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6150144.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            4130..5638
                     /gene="glpK"
                     /locus_tag="VVR43_001831"
     CDS             4130..5638
                     /gene="glpK"
                     /locus_tag="VVR43_001831"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU6150145.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5680..7506
                     /gene="glpO"
                     /locus_tag="VVR43_001832"
     CDS             5680..7506
                     /gene="glpO"
                     /locus_tag="VVR43_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU6150146.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKRTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALAQNDLAELKN"
     gene            7576..8280
                     /locus_tag="VVR43_001833"
     CDS             7576..8280
                     /locus_tag="VVR43_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU6150147.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8577..8780
                     /locus_tag="VVR43_001834"
     CDS             8577..8780
                     /locus_tag="VVR43_001834"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150148.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(8867..9454)
                     /locus_tag="VVR43_001835"
     CDS             complement(8867..9454)
                     /locus_tag="VVR43_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150149.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
BASE COUNT         2897 a         1964 c         2216 g         2804 t
ORIGIN      
        1 gaggttaaac cgcagctaga aaaaccaaaa ccagaggtta aaccgcagct ggaaaaacca
       61 aaaccagagg ttaaaccgca gccggaaaaa ccaaaaccag ataatagcaa gccacaagca
      121 gatgataaga agccatcaac tacaaataat ttaagcaagg acaagcaacc ttctaaccaa
      181 gcttcaacaa acgaaaaagc aacaaataaa ccgaagaagt cattgccatc aactggatct
      241 atttcaaatc tagcacttga aattgcaggt cttcttacct tggcgggggc aaccattctt
      301 gctaagaaaa gaatgaaata gtgattgatt cattcaaaaa tgtttgtaaa aagtattcga
      361 cttaaaagaa aagagtctgg gataaaaaga ttttgatttt aggaattctt tattataaat
      421 ttttaaaatc gatagattag acaaaaaagc gaacaagaca gaattctgag tgtcagataa
      481 ctgattttgt tcgcttttta tatttaatat tatacttttg tcctaggctc ttttttgcat
      541 tatacttttt ccaattgcaa gagagcttca atctctgcta gggtgctagc ttgcgaaatg
      601 gctccacgga gtttggcagc gccagatgtt ccacggagat agtgaggagc gaggccgcgg
      661 aattcacgaa ctgcgacgtt ttctcctttg aggttaatca atcgtttcaa gtgttcgtag
      721 gcgatcttca tcttgtcttc aaatgtcaaa tcaggtagga tttctcctgt ttcaaagtaa
      781 tggttgattt ggttgaagag gtaaggattt cccatggcag ctcggccaat catgactgcg
      841 tcagcaccaa cttcttcgat gcgttgcttg gcttcttgga cagtacggat atcaccgttg
      901 gcgatgaatg gaatcttggt tagagcttgg gcaaccttgt aaagggtctc aaggtccgcg
      961 tggccagtat acatttgttc acgggtacgg ccatgcatgg cgagggcaga aacacctgca
     1021 gcctcagcag cgagggcatt ttctactgca agagatgggt ccgcccagcc ggtacgcatt
     1081 ttgacagtaa gtgggatatc aaggacagac tggaccttgt tgatgataga gtagatcttg
     1141 tcaggaccct tgagccacat agcaccagct tcgttcttca cgattttgtt gacagggcag
     1201 cccatgttga tatcgacgat atcggtcttg gtgttttctt ggatgaattc tgctgcgcgt
     1261 gctaggctgt cttcatcgct accaaaaagt tggatagaga cagggttttc gccctcatcg
     1321 atatgaagca tgtgcagggt tttttcgttg ttgtattgga ttcccttgtc agagaccatt
     1381 tccattacaa cgagtccagc tccaagctct tttgctatgg tacgaaaggc tgagttggtc
     1441 acgccagcca taggcgctaa aacggtacga ttgggaatct caatattgcc aatcataaaa
     1501 ggtgtattaa gatttgtcac gaatgagttc ctccaggtcc ttttcatcaa agttgtaagt
     1561 agtttggcag aattgacaag tgatttctgc accgtggtct tcctctttca tttcctgtaa
     1621 gtctgagctt ggaaggctgg caagagcgtt cataaagcgt tcatggctac agtcacattg
     1681 gaaacggatt tcttcttcag aaagacgctt gtaggcttcg tccccgtaga tagccttgag
     1741 gagggcttcg atatggtcgt cgctttcgag aagagtagag atagctggca tttcttggat
     1801 gcgtttttca aagcgagcaa tctcttcttt cttggctcct ggcaagactt gaactaggaa
     1861 accacctgca accttgacct tgtcttcctc gtccaaaagg acattgaggc cgaccgctga
     1921 aggcgtttgt tggctttcag taaggtaaaa ggcaaggtct tcaccgattt ctccagagat
     1981 gaggggagtt atagagttgt aaggatttcc agtaccgtag tctgtgataa cgaggaattg
     2041 accatttcca acaaaaggtc cgactaggac ttcaccagtc gcagtctttt tgatgtcaac
     2101 accaggattt tgaacatagc ctttgacgtt ccccttggta tcagcgacgg tgataatagc
     2161 acctagagag ctagatccca acaccttaac tgtaagtttg gtatttcctt tttcattggc
     2221 tgcgagaatc tggctagcga taagagttcg accaagcgct acagttgagc tagcttgggt
     2281 ttgatgtttt tcttgagcag tgcggacggt ttcagtgcta tcaaggacaa aagcacgaaa
     2341 ggctccgctt tctgatatag ttttaataat tttatccata gctactattt tagcataaaa
     2401 atgcccaaag ggggagccgt gtgtttactg attttcagga taatggacca ggaaatcagc
     2461 atgaaaataa aaagagaaac agattatttt agcatttgtc agatttatgc tatgcttaag
     2521 gtagaaaatg aaaggggtaa caaatgtatt taggagattt gatggagaaa gccgagtgtg
     2581 gtcaattttc aatcctttcc tttctattac aagagtctca gacgaccgtc aaggctgtaa
     2641 tggaagaaac aggattttca aaagcaaccc taaccaaata tgtcaccctg ctcaatgaca
     2701 aggctttgga tagtggctta gagctgacta ttcactcaga agatgaaaat ctgcgtctgt
     2761 ctatcggtgc agctaccaag gggagagata ttcggagctt gtttttggag agtgctgtta
     2821 aataccagat tttggtttat cttctctacc accaacagtt tttagcccat cagctggctc
     2881 aagaattggt gattagcgag gctacgcttg gtcgtcactt ggctggttta aatcagattt
     2941 tgtcagaatt tgatttatcc atccaaaatg gacgttggcg aggtccagag catcagattc
     3001 gctatttcta tttctgtctt ttccgaaagg tctggtcgag tcaggaatgg gaaggtcaca
     3061 tgcagaaacc agagagaaaa caggagattg ccaatttaga ggaaatctgc ggtgcaagtt
     3121 tgtctgcggg gcagaaattg gacttggttc tctgggctca catcagtcaa caacgtcttc
     3181 gggtcaatgc ttgtcagttt caagtcatag aagagaaaat gcgagggtat tttgacaata
     3241 tcttttatct tcgtttgctg agaaaggttc cgtccttttt tgctgggcaa catattccac
     3301 taggagttga ggatggtgag atgatgatat tcttctcttt tctcctatct catcgcattc
     3361 ttcctcttca tactatggag tatattcttg gttttggagg gcagttggca gatttactga
     3421 cgcaattgat tcaagaaatg aagaaggagg aactattggg ggattataca gaggaccatg
     3481 tcacctatga actcagtcag ctttgtgctc aagtctatct ctataagggc tatattttac
     3541 aggatcgcta caagtaccag ttagagaatc gtcatccata tttactgatg gaacatgatt
     3601 ttaaagagac agcagaggag atttttcatg ctctgcctgc ttttcaacag gggacagatt
     3661 tagataagaa gattctctgg gaatggctcc agttaatcga atatatggct gaaaacggtg
     3721 gccagcatat gcggattggt ctggatttga catctggttt tcttgtcttt tcaaggatgg
     3781 cagccatttt gaaacggtat ttggaataca atcgttttat taccattgaa gcttatgacc
     3841 ctagtcggca ttatgatttg ctggttacca ataacccgat tcataagaag gaacagacac
     3901 cagtctatta tttaaaaaac gacttggata tggaagattt ggcagggatt cgtcagttat
     3961 tattcactta aaaggcttgg ttaatccagg tcttttttgt gaaattcaca caatctcctc
     4021 acattttttt aaaaattaaa aaaagttgat aaacaagaaa gcgctttatt ttgtatacta
     4081 gtaagtgtaa agaggaaaca cctcaagatc tttatcagga ggacagtata tgtcacaaga
     4141 aaaatacatc atggccattg accagggaac tacaagttct cgtgccatca ttttcaacaa
     4201 aaaaggggaa aaggttagct cgagtcaaaa agagtttacc cagattttcc ctcaggcagg
     4261 ttgggttgag cacaatgcca atgaaatttg gaactctgtt cagtcagtta ttgcgggtgc
     4321 tttcatcgaa agtggtgtca agccaaatca aatcgaggca atcgggatta ccaaccaacg
     4381 tgaaacaacg gttgtctggg ataagaaaac aggacttcct atctacaatg ctatcgtttg
     4441 gcagtcacgc cagacagcac ctttggctga gcaactaaaa agccaaggtt atgtggaaaa
     4501 attccatgaa aagactggtt tgattattga tgcttacttc tctgctacca aggttcgttg
     4561 gattttggat catgtagaag gtgctcaaga gcgagcagaa aaaggggaat tgctctttgg
     4621 tactatcgat acttggttgg tttggaaatt gactgacggt gcggctcacg tgactgacta
     4681 ctcaaatgca gctcgtacca tgctttataa cattaaagaa ctcaaatggg atgatgagat
     4741 tttggaaatc cttaacattc cgaaggctat acttccagaa gttcgttcta actccgaaat
     4801 ctacggcaag acagctccat tccatttcta cggtggagag gtgccaatct caggtatggc
     4861 tggggaccaa caagcagccc tctttggaca gttggctttt gagccaggta tggttaagaa
     4921 tacttatgga acaggctctt tcatcatcat gaatactggg gaagagatgc agttgtctga
     4981 aaacaacctc ttgacaacca ttggttacgg aatcaacggt aaggtttatt atgccttgga
     5041 aggttctatc ttcatcgcag gaagtgctat tcagtggctt cgtgacggtc ttcgcatggt
     5101 tgaaaattca ccagaatctg aaaaatacgc tcgtgattct cacaacaacg atgaagttta
     5161 tgtcgttcca gcctttacag gtctaggcgc tccatactgg aaccaaaatg ctcgtggttc
     5221 cgtctttggt ttgactcgtg gaacaagcaa agaagacttt atcaaggcga ctttgcaatc
     5281 tattgcttat caagtgcgtg atatcatcga caccatgcaa gtggatactc agaccgccat
     5341 tcaagtactg aaggtggatg gtggtgcagc catgaacaac ttcctcatgc agttccaggc
     5401 ggatatttta ggcattgaca ttgcacgtgc taaaaacctg gaaacaacag ctctaggagc
     5461 ggccttccta gcaggtttgt cagtagggta ctggaaagac ttggacgagt tgaaactctt
     5521 gaacgagaca ggagaactct ttgagccatc tatgaacgaa tctcgcaagg aacaactcta
     5581 caagggctgg aagaaggctg tgaaagcaac tcaagtcttt gcggaagtag acgactaata
     5641 ctggcagaat aaagcgattt atttagaaag tgtgtaaata tggaattttc aaagaaaaca
     5701 cgtgaattgt caattaaaaa aatgcaggaa cgcaccctgg acctcttgat tatcggtgga
     5761 ggaatcacag gagctggtgt agccttgcag gcggcagcta gcggtcttga gactggtttg
     5821 attgaaatgc aagactttgc agaaggaaca tctagtcgtt caacaaaatt ggttcacgga
     5881 ggtcttcgct acctcaaaca attcgacgta gaagtggtct cagatacggt ttctgaacgt
     5941 gcagtggttc aacaaatcgc tccacacatt ccaaaaccag atccaatgct cttaccagtt
     6001 tacgatgaag atggagcaac ctttagcctc ttccgtctta aagtagccat ggacttgtac
     6061 gacctcttgg caggtgttag caacacacca actgcgaaca aggttttgag caaggatcaa
     6121 gtcttggaac gccagccaaa cttgaagaag gaaggcttgg taggaggtgg agtgtatctt
     6181 gacttccgta acaacgatgc gcgtctcgtg attgaaaaca tcaaacgtgc caaccaagac
     6241 ggtgccctca ttgccaacca cgtgaaggca gaaggcttcc tctttgacga aagtggcaag
     6301 attacaggtg ttgtagctcg tgatctcttg acagaccaag tatttgaaat caaggcccgt
     6361 ctggttatta atacaacagg tccttggagt gataaagtac gtaatttgtc taataagaga
     6421 acgcaattct cacaaatgcg cccaactaag ggagttcact tggtagtgga ttcaagcaaa
     6481 atcaaggttt cacagccagt ttactttgac acaggtttgg gtgacggtcg tatggtcttt
     6541 gttctcccac gtgaaaacaa gacttacttt ggtacaactg atacagacta cacaggtgat
     6601 ttggagcatc caaaagtaac tcaagaagat gtagattatc tacttggcat tgtcaacaac
     6661 cgcttcccag aatccaacat caccattgat gatatcgaaa gcagctgggc aggtcttcgt
     6721 ccattgattg cagggaacag tgcctctgac tataatggtg gaaataacgg taccatcagt
     6781 gatgaaagct ttgacaactt gattgcgact gttgaatctt atctctccaa agaaaaaaca
     6841 cgtgaagatg ttgagtctgc tgtcagcaag cttgaaagta gcacatctga gaaacatttg
     6901 gatccatctg cagtttctcg tgggtctagc ttggaccgtg atgacaatgg tctcttgact
     6961 cttgctggtg gtaaaatcac agactaccgt aagatggctg aaggagctat ggagcgcgtg
     7021 gttgacatcc tcaaagcaga atttgaccgt agctttaaat tgatcaattc taaaacttac
     7081 cctgtttcag gtggagaatt gaacccagca aatgtggatt cagaaatcga agcctttgcg
     7141 caacttggag tatcacgtgg tttggatagc aaggaagctc actatctggc aaatctttac
     7201 ggttcaaatg caccgaaagt ctttgcactt gctcacagct tggaacaagc gccaggactc
     7261 agcttggcag atactttgtc ccttcactat gcaatgcgca acgagttggc tcttagccca
     7321 gttgacttcc ttcttcgtcg taccaaccat atgctcttta tgcgtgatag cttggatagc
     7381 atcgttgagc cagttttgga tgaaatggga cgattctatg actggacaga agaagaaaaa
     7441 gcaacttacc gtgctgatgt cgaagcagct ctcgctcaaa acgacttagc agaattaaaa
     7501 aattaagaaa aaataaaaga ggtggagggc agcattcctt gtcgcccgtc ccttcttttt
     7561 aatggagaca gaaagatgat gaatgaatta tttggagaat ttctagggac tttaatcctg
     7621 attcttctag gaaatggtgt tgttgcaggt gtggttcttc ctaaaaccaa gagcaatagc
     7681 tcaggttgga ttgtgattac tatgggttgg gggattgcag ttgcggttgc agtctttgta
     7741 tctggcaagc tcagtccagc tcatttaaac ccagctgtga ccatcggtgt ggccttaaaa
     7801 ggtggtttgc cttgggcttc cgttttgcct tatatcttag cccagttcgc aggggccatg
     7861 ctgggtcaga ttttggtttg gttgcaattc aaacctcact atgaggcaga agaaaatgca
     7921 ggcaatatcc tggcaacctt cagtactgga ccagccatca aggatactgt atcaaacttg
     7981 attagcgaaa tccttggaac ctttgttttg gtgttgacaa tctttgcttt gggtctttac
     8041 gattttcagg caggtatcgg aacctttgca gtgggaactt tgattgtcgg tatcggtcta
     8101 tcactaggtg ggacaacagg ttatgccttg aacccagctc gtgaccttgg acctcgtatc
     8161 atgcacagca tcttgccaat tccaaacaag ggagacggag actggtctta cgcttggatt
     8221 cctgttgtag gccctgttat cggagcagcc ttggcagtgc ttgtattctc acttttctag
     8281 tttatactct tcgaaaatca aattcaaacc acgtcagcgt cgccttaccg tactcaagta
     8341 cagcttgcgg ctagcttcct agtttgctct ttgattttca ttgagtatta gaaaacaatt
     8401 atgttgatag agcttgggca agagcccaat ttcagcaaaa aatgaagtaa atcttctcat
     8461 aataaaacgc atcatatcaa gcacgaaaat tccacgaggt caactacagt cagaaagctg
     8521 aacaacaagc caaaacgccc aaaaaaggcg gcaaaaagca agcacctgca agcaacgtgc
     8581 cgaaatggtc aaatcctgat tatgtcaacg aattagaccc aaaaatcgtt gatatgctag
     8641 tagaatttca caagtcacaa ggcactttgg aaactcccga ggcgcaagca gaaatcgccc
     8701 aaaaacgtga agaaatcgag caaaggagag ctgagcttga gggtaaaaaa caagagcttt
     8761 tgaaccgctt gaacaaatag agtttcgcaa gtattatgct tacaaattac ttgagcaatt
     8821 aactaaaata taaaccctgc ctttatatct aggcagggtt tatattttag aaattcacgt
     8881 aggttgttac ggtttttaca tacccagtat agtttgagtt tctatagtat tcagtgataa
     8941 acttccattt tctttgagca acatggatat aagtacttgt tatgtagtat ggatatgggc
     9001 tttgtgaatc caagtaagac tgataagctt gtataccaaa atatgctcca ccaattattg
     9061 caccccatgg accccccaat aaagcaccta tcctaccaat catataactg attccagcac
     9121 cagtcatgaa gttagcgaat gtgttagctt gtttattccc atgtattgtg ttgacgtaat
     9181 tccaaacatt aggatcgtat gatctaaaag atatatttag gtcgatttca ttcttttgat
     9241 aagccatata aaatgcccca ttgatataga cgccgtcagc acgtcgttca atagtgtcta
     9301 cacttccatc tggattgaca acctcaagaa cttcatcgct taaaatattt acttgcgtat
     9361 ctccgaaccg cactgatgag ccattctcaa actgagcctc accagataca actttagagt
     9421 ttgccgataa gctatcatca gcaaaaacaa acaagcgacg gggaaatgct agacatacag
     9481 aaaacagaca taactagcaa acacatgcat ttaaacatct tagacataac ggaaactcct
     9541 ttgtattttt gatttttttc aacttttatt atacaataaa accaaataaa aagaaagcgg
     9601 taacaatatg cttaatgcga aaatttttta tatattttta tgtttgatcg ttatcgaaac
     9661 tacaggcttg ttgttgttga aaagaggtct cgaaatgggt tatttagaca cagaagctat
     9721 tatcctcgca gttttttcat ttgcttttta caacctatgt tcattcgctt gggtctgctc
     9781 tacaataaaa aacaataaaa aataaataga cgtattttca aaaaaaaaaa aaatgcatat
     9841 ttatcttagc aaaacgacga tttaaatcgt cgtttttttg t
//
LOCUS       DAVHSY010000055         9613 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.056, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000055 DAVHSY010000000
VERSION     DAVHSY010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9613
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.056"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            231..326
                     /locus_tag="VVR43_001836"
                     /pseudo
     CDS             231..326
                     /locus_tag="VVR43_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(579..1199)
                     /locus_tag="VVR43_001837"
     CDS             complement(579..1199)
                     /locus_tag="VVR43_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU6150150.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1199..1681)
                     /locus_tag="VVR43_001838"
     CDS             complement(1199..1681)
                     /locus_tag="VVR43_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU6150151.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1681..2523)
                     /locus_tag="VVR43_001839"
     CDS             complement(1681..2523)
                     /locus_tag="VVR43_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU6150152.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2618..3406)
                     /locus_tag="VVR43_001840"
     CDS             complement(2618..3406)
                     /locus_tag="VVR43_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU6150153.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQALK
                     HLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDKTYKS
                     HITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTMSNMN
                     EGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLESSPKT
                     DLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3550..4929
                     /gene="glmU"
                     /locus_tag="VVR43_001841"
     CDS             3550..4929
                     /gene="glmU"
                     /locus_tag="VVR43_001841"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU6150154.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLTGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4939..5484
                     /locus_tag="VVR43_001842"
     CDS             4939..5484
                     /locus_tag="VVR43_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6150155.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5496..5810
                     /locus_tag="VVR43_001843"
     CDS             5496..5810
                     /locus_tag="VVR43_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU6150156.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5827..6519
                     /locus_tag="VVR43_001844"
     CDS             5827..6519
                     /locus_tag="VVR43_001844"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU6150157.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYSYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHFGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6596..7087
                     /gene="rocS"
                     /locus_tag="VVR43_001845"
     CDS             6596..7087
                     /gene="rocS"
                     /locus_tag="VVR43_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU6150158.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7185..7775
                     /locus_tag="VVR43_001846"
     CDS             7185..7775
                     /locus_tag="VVR43_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU6150159.1"
                     /translation="MERLEDYIAFDLEFNQHEGQKHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     YGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7784..9547
                     /locus_tag="VVR43_001847"
     CDS             7784..9547
                     /locus_tag="VVR43_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU6150160.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         2982 a         1665 c         2051 g         2915 t
ORIGIN      
        1 gtagttcatg tacacctgat atgatgcgtt ttataatttt aaagactttt tgaccagcct
       61 cattttttta acttgatact cagtgaaaag caaagattaa actaggaagc tagctgtagg
      121 ctgctcaaag aacagctttg aggttgcaga taaaacttgt gaggtaacca acatatataa
      181 tgtgaagctg acgtggtttg aatagatttt agaagggtat gagtctggaa gttttaatgg
      241 ataatgcaag attccataga atgggtaagc tagagttctt atgtgaagag tttgggcata
      301 aacttttacc ttttcctccc tactcatctt agtatagaaa agtgaatcta aaatagtaca
      361 taactgcttc taaaacattc ttataaattg atttaaattc tcaaatcata ttattcagtt
      421 cttatttcat tttgctctac aatcctgttg agaagacacg tgttcatatc aaaaaggtat
      481 tggcaagttg caataccttt ttacaaggtt cttttgtctt atttttgttt caactgacta
      541 tatctcctat ggttctagtt cagaaggcta ggctataatt atgattgata agaagtatca
      601 ttccaagtat tgagagtgaa tgtttcaaaa tcatgggttt ctataatggt caggctggca
      661 tttgctagac cgccatcttt acgaagaagt ggttctttat agcctaggag agtacgaaga
      721 ctggcagtaa gattggcgcc gtgtccgaca attagaatac gctcagctgg actatctttt
      781 aatgatttga taaattggat ggtccgctga gttgtactat agagggattc ggctccgaac
      841 attcgagtgt caaattgagc aagatttgaa cgaaaagcct ggatttgttg cgggtaaata
      901 gcttccaggg ttgcaatttt caaaccttct aacttcccaa gttgccattc acggagatta
      961 ggaacgattt ctaaagaaca gggggtatgg agttgacttt ggataatctc agcagatttg
     1021 accgctcgag gtaaatcact tgaataaatc tgatcaaaag gaatttcctt gagatactgg
     1081 ccaagtcgtt ttagggtttc aatggattca ggaagaagag gagaatcacc gctagcacct
     1141 tgaaaacgac cttcttggtt ccagagggta cgaccgtggc ggacaaagta gagtttcatt
     1201 acttgatgtc ctccaaaata tctacaaagt ctgcctttac aaagctagcc aagtcttgtg
     1261 gcgcgacgat aatgctgtgt ccgacttcgc ctgcagagac aatcattcga tccaaatcta
     1321 gagcaatttt atcgataaaa atgggataat tgtgtttctg acgaattccg acaggattat
     1381 tggctccatg aatgtaacca gttgtttttt ctaagtcctt ttgtggaatc atgctcactt
     1441 ttttattgcc agaaatttta gctagtttct tttcagacaa gtgctgagtg atagggacaa
     1501 ttccgataat cggtccggtc ttgtctccca aaagcgccaa ggttttgaaa atctgatctc
     1561 gttcataacc ttgaggaagc tctccttcta gggcattgat ttgaatcccc tgatgaggga
     1621 tagctgcttt agataggatt tgttccacca atgttttttt gattttaact ttttttgcca
     1681 ttatttatat ttatcctcca attgactcat ccaaatacca agccagattc ccagcgcaaa
     1741 gaagaaggcg atgatgacat aaccgacaag tgaaagtcct gtgtattgga tactttcagc
     1801 gtttcctgca tttggaatta agatcaaaag ggtacttgat aggacgatac cgatgatgaa
     1861 atgatagacg cgtgagtggt agttgtttaa ggcataatcc atcaattttg aaaaaacgat
     1921 gagagttgca cctgcaccaa ttccaatcgg aaagaaggtt cccaagaaat caaaagtttt
     1981 aaaaccagtc aacataggag catatagtcc caaaatcaaa agtaaatttg atgggctgag
     2041 gccaggaacc aagacgccaa gggccaatag tgcgcctgct aggacgaagt taagaaagct
     2101 ggcgcttaag gttccaacga caaaatttaa ggcatagagt cctaatccag aaatgataaa
     2161 ggttgtccat aaccaagcta aatcaatctt gtctcggtca gattctcgag ttgattcttt
     2221 gaggaggcta ggaactgtac cgataatagc tcccgcaaag ctccataata caaaaacctg
     2281 ataattttca agcaggtatt caatcgggta ggaaaataag ccgattccca gaagcatacc
     2341 gatggcaact ggaataaagt acaaaacatt ttctttaaag tctttaaagg gatgggccag
     2401 aaagccaatc attcgttcat agattcctaa gattgctgct agaacccctc cggaaattcc
     2461 cggtaggata aatccaagag caattacaat ccctttaata acgcgtgcta accatgagag
     2521 catatatttc ctccaactat ttctatttca aaaaatcctt actatattgt atcacaatca
     2581 gacacaaaaa gaaaaagcaa atgataaaca aatgctttta aggttttaaa aaaagttttc
     2641 gaaaggtttc ttctttattt tttaagggag agataacgtt gatatctaaa tcgtggtcaa
     2701 agccggcaat ttttccttta gatgtgtatt ggtgaatatc ataatctaaa tcagttttag
     2761 gactgctctc caaaaatcct gagtctgagc cgtaggacgg aatccaaaca gaggtaaact
     2821 tgcctgtatc aatactgtgt tcttccatga agtagacacc aacgtagatg ccgatgtttt
     2881 tagcacctag tgatgctagt tttgctcgaa agttttcgac accttcgttc atattagaca
     2941 tggttttgtc ttccacgtca agccaatagt aactagggct gtaaggagag gcagcattgt
     3001 agaaaacttc ggcagccttt tccatttctt ggacactttt tccagctaca taagcgtaga
     3061 cagcaactgg gacattccgc ttttgaagtt cagtgatatg actcttatag gtcttgtcta
     3121 ttccattgat aaatgaagca tcattttctt ttgttgtttg agcaccactg tgaacacgaa
     3181 caatagcacc tgaaatattt tgtgagaggg catcgtagtt gatttcctca ggacgctgcc
     3241 agccagagag gtcaataatc ggtttgtcta agtgtttcaa agcctgtgct atattggatt
     3301 ttgttttaaa cgattggctg tcattaagtg ggcgattgat gattaaaatg aacatcataa
     3361 tcccaaaaaa actaaataaa ataagtggat gaatttgttt tctcatatct tataagtcta
     3421 ccctaaaaat caaaaaaaat caaaaaaatg ggttaaggaa gagactttag agcatttttt
     3481 cattcaagag tgcggaatga tttgaaatat ggtataataa aagggaattt ctacagaaaa
     3541 gagaagatta tgtcaaattt tgccattatt ttagcagcgg gtaaagggac tcgcatgaaa
     3601 tctgatttgc caaaagtttt gcacaaggtt gcgggtattt ctatgttgga acatgttttc
     3661 cgtagtgtgg gagctatcca acctgaaaag acagtaacag ttgtaggaca caaggcagaa
     3721 ttggttgagg aggtcttgac tggacagaca gaatttgtga ctcaatctga acagttggga
     3781 actggtcatg cagttatgat gacagaacct atcttagaag gtttgtcagg acacaccttg
     3841 gtcattgcag gagatactcc tttaatcact ggtgaaagct tgaaaaactt gattgatttc
     3901 catatcaatc ataaaaatgt ggccactatc ttgactgctg aaacggataa tccttttggc
     3961 tatggacgaa ttgttcgtaa tgacaatgct gaggttcttc gtattgttga gcagaaggat
     4021 gctacagatt ttgaaaagca aatcaaggaa atcaacactg gaacatacgt ctttgacaac
     4081 gagcgtttgt ttgaggcttt gaaaaatatc aataccaata acgctcaagg cgaatactat
     4141 attacagacg tcattggtat tttccgtgaa actggtgaaa aagttggcgc ttatactttg
     4201 aaagattttg atgaaagtct tggggtaaat gaccgtgtgg cgcttgcgac agctgagtca
     4261 gttatgcgtc gtcgcatcaa tcataaacac atggtcaacg gtgttagctt tgtcaatcca
     4321 gaagcaactt atatcgatat tgatgttgag attgctccgg aagttcaaat cgaagccaat
     4381 gttaccttga aagggcaaac gaaaattggt gctgagactg ttttgacaaa tggtacttat
     4441 gtagtggaca gcactatcgg agcaggagcg gtcattacca attctatgat tgaggaaagt
     4501 agtgttgcag acggtgtgac agtcggtcct tatgctcaca ttcgtccaaa ttcaagtctg
     4561 ggtgcccaag ttcatattgg taactttgtt gaggtgaaag gatcttcaat cggtgagaat
     4621 accaaggctg gtcatttgac ttatatcgga aactgtgaag tgggaagcaa cgttaatttc
     4681 ggtgctggaa ctattacagt caactatgac ggcaaaaaca aatacaagac agtcattgga
     4741 gacaatgtct ttgttggttc aaattcaacc attattgcac cagtagaact tggtgacaat
     4801 tccctcgttg gtgctggttc aactattact aaagacgtgc cagcagatgc tattgctatt
     4861 ggtcgcggtc gtcagatcaa taaagacgaa tatgcaacac gtcttcctca tcatcctaag
     4921 aaccagtagg agcctatcat ggagtttgaa gaaaaaacgc ttagccgaaa agaaatctat
     4981 caaggaccaa tatttaaact ggtccaagat caggttgaat taccagaagg caagggaact
     5041 gcccaacggg atttgatttt ccacaatggg gctgtctgtg ttttagcagt aacggatgaa
     5101 caaaaactta tcttggtcaa gcagtaccgc aaagctatcg aggcagtctc ttacgaaatt
     5161 ccagccggaa aattggaagt aggagaaaac acagcccctg tggcagctgc ccttcgtgaa
     5221 ttagaggaag aaacagccta tacagggaaa ttagaactct tgtacgattt ttattcagct
     5281 attggctttt gtaatgagaa gttaaaacta tatttagcaa gcgatttaac aaaagtggaa
     5341 aatccgcgtc cgcaggatga ggatgaaacc ttggaagtcc ttgaagtgag cttagaagaa
     5401 gcgaaagaat taatccaatc aggtcatatt tgtgatgcca agacaattat ggctgttcag
     5461 tattgggagt tgcagaaaaa atagaggagg tcagtatggg taaatcttta ttaacggatg
     5521 aaatgattga aagagctaat agaggcgaaa aaatttcagg tcctcctttg ctagatgata
     5581 atgaggaaac taagatttta ccaacctctt cttcccgttt tggttatgcc aatcctaagg
     5641 atcatggttt tagccaggaa accttgaaga ttcaggtcga accatctatt cataaaagcc
     5701 gtcgtattga aaataccaag agaaatgtct tcaattctaa gttgaataaa atcttatttg
     5761 cggtcatttt tctcttgatt ttgcttgttt tagcaatgaa acttttgtaa tagaaaagga
     5821 attgaaatga aaataggaat tattgctgct atgccagaag aactggctta tctggtccag
     5881 catttagata atgcccagga gcaagttgtt ttggggaata cctatcatac aggaaccatt
     5941 gcttctcatg aagtcgttct tgtagaaagt ggaattggta aggtcatgtc tgctatgagt
     6001 gtggcgattt tggctgatca tttccaggtg gatgccctta ttaatacggg ttcagctggg
     6061 gcagtagcag aaggtatcgc tgttggggat gtcgtgattg ctgacaaatt agcctatcat
     6121 gacgtggatg tcacagcttt tggctattct tatggacaaa tggcgcaaca accgctttat
     6181 ttcgaatcag acaaaacctt tgttgctcaa atccaagaga gtttatctca attggaccaa
     6241 aactggcatt ttggtttgat tgctacagga gatagttttg ttgcaggaaa tgacaagata
     6301 gaagcgatta agtcccattt cccagaagtt ttagccgtgg agatggaggg ggcagctatt
     6361 gctcaagcag cgcatgccct caatctccca gtcttagtca tcagagctat gagtgacaat
     6421 gccaaccatg aagcaaacat cttttttgat gagtttatta tcgaagctgg acgtcgctct
     6481 gcccaagtct tgttgacctt tttgaaggct ttagattaag cggaaatttg acagtttttc
     6541 tagcttatga taagatttaa gtaaagaaaa gctagaaaac gtttcagagg atattatgag
     6601 tattgaaatg accgtcagtg agattgcaga ggtcttagga ttatctcgcc aagcaatcaa
     6661 taaccgtgtc aaagaattac cagaagaaga cacagataaa aatgacaaag gggtaacagt
     6721 tgttaccaga agtggcttga ttaagctaga agaaatctat aaaaaaacga tttttgaaga
     6781 tgagcctgtc agtgaagatg tcaaacaacg tgaactgatg gagattctag tggatgagaa
     6841 gaatgcagaa attcttcgtc tttatgaaca attaaaagcc aaggatcgtc agttatcaga
     6901 aaaagacgag cagatgcgta tcaaagaccg tcagattgct gagaaagaca aacaattaga
     6961 tcagcaacaa caattgaccc ttcaagccat gaaggatcaa gaaaatctta agctagagct
     7021 ggaccaagca aaagaagaag tccaatccac taaaaaaggc ttttttgctc gtttatttgg
     7081 aggataatca aggagctgtt taggttaaat gctaacctga tggcttcttt tgtttgtgaa
     7141 tagtatagtt gattagaaca gagacagtag aggagaggta cagaatggaa cgattagaag
     7201 attacattgc ttttgactta gaatttaatc agcacgaagg acaaaaacac ttgattcaag
     7261 tatcggcagt gcgttttaga gatggtcggg aaatcgatgc ctatgattcc tatgttcata
     7321 ccagcgtccc tctaaaaagc tttatcaatg gtttgaccgg gattacagct gagaccttaa
     7381 aagatgctcc tccagttgag aaagtcttag aagaattcca agagtttgtg ggttctttgc
     7441 tgatgatagg ctacaatgct gctaaaagtg atttacctat tttagcagag tatggtttag
     7501 actatagcca acagtacaag gtggatttgt atgatgaagc ttttgaacgt cggagttcag
     7561 atttacatgg tattgccaat ctcaaattgc aaactgttgc ctcatttctt ggatttcaag
     7621 gtcagtctca taatagttta gaggatgctc ggatgacggc gcgtgtttac gaatccttct
     7681 tagagtcgga tcaagctagg gaattgttag agacagaaag tagcttatca aacaatcctt
     7741 ttggtggctt ggacttgtct caattatttg actaggagtg cctatgaaac ctgaaaaacc
     7801 taaaaaattg ggtcttaaac agatttacct caatcttgat aaaatcctct ttctattttt
     7861 cttgattttt atgatagtgg agtatttgtg ggtaccattc aattcatggt tggctagctt
     7921 cttattagat cagacaggtt atctttttat ttcctataac aatgtcttag ccatccttac
     7981 tcattctcca ttgattagtc tagctttttt agccttgatt gtaattaacc ttctggttgc
     8041 ttattttcaa ataggactcc tctttattgg tgctcgtcat ctcctctata atgaaaagcg
     8101 aaggctaatt gagtatatcc gcaaggtttt ccatgaaagt tttggattta tgaaaaagct
     8161 aacttgcgct aaagccttgt ttatcttttt ctatatagct atgctttttc cttttatacg
     8221 gaaaatgctg aagatttatt atcttaataa aatcgtcatt ccagagttta tccaagctta
     8281 tttagaagat aaatattgga tgtggtggct gagcatccta cttctatctc ttatctttct
     8341 ctatgtctct gtcagattga tgtttgccct tccgaagatt gtatatgatc agctgactgt
     8401 tcgagaagca gtgatgttta gcttggagaa aaccaagaag agagttactt tttatgcttg
     8461 gaatttattt tacatcttgc tcaaagcaca tttattattt tatcttcctt tgattccttt
     8521 attattggct caaactttgg tagatgatat cactcagaga gagtctctga ttcttggtat
     8581 tttgaatttt gtcgtgatta aaaatctata ttatatggct ctgacttatt ttttggttaa
     8641 atttgtttca tttttgacag gaaaggagct ggatatgctt cctaggagag aaaaagatca
     8701 catcgtgcga tggggtgtca tgacttgtgc cagtcttttc tttgccttag aaggttatat
     8761 ttatctggag gctcccatgg ttcatctacc tcaacttatt tctcaccgag gggtttccaa
     8821 tgcaaatggg attcaaaata cagtagagtc cttggaaact acagcacaac tcaaaccaga
     8881 cttggtggag acggacgtgc aggaaacaaa agatgggcag tttgtcatga tgcatgatgc
     8941 taacttgaaa aatctagcag gtatcaataa aagtcctcaa gacttaaact tggaggagct
     9001 taaagggatt gatatttttg aaaatggcta ccagactaaa atttcaagct ttgaagatta
     9061 tctcagtcga gccaacgaac ttggtcaaaa attactaatt gaaattaaaa ccagtaaaaa
     9121 agatagtcca gacatgatga accgcttttt agcccgttat gctgcaaagc tcaagattta
     9181 tggacatcaa atccagtctt tagactacca tgttgtcgaa aaagtaagac agtatgatgc
     9241 cgaactgcca gtttatttca tcatgcccta caattctgtc tttcctaaaa caagagcgac
     9301 aggatatact atggagtact caaccttgga tgaatatttt gtaagcaaac tatggacaac
     9361 ggatcagaaa ctttatgtct ggactgtcaa tgattcagaa gctatcagca aatctcttca
     9421 cttaggagta gatggagtga ttacagatga tttggaaaaa gttcagcggg aaatagaagt
     9481 agcccaagaa gatccagaat atacggattt gctcttgaaa aaagcattgg aattctttga
     9541 attttagtaa taaaaaagag gaacggttgt tcctcccatg ataggtaagt attcttgtga
     9601 atgcttgctt ttt
//
LOCUS       DAVHSY010000056         9006 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.057, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000056 DAVHSY010000000
VERSION     DAVHSY010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9006
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.057"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(334..1182)
                     /gene="dprA"
                     /locus_tag="VVR43_001848"
     CDS             complement(334..1182)
                     /gene="dprA"
                     /locus_tag="VVR43_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU6150161.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLALSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1278..1967)
                     /locus_tag="VVR43_001849"
     CDS             complement(1278..1967)
                     /locus_tag="VVR43_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU6150162.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1979..2857)
                     /locus_tag="VVR43_001850"
     CDS             complement(1979..2857)
                     /locus_tag="VVR43_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU6150163.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2847..3716)
                     /gene="licA"
                     /locus_tag="VVR43_001851"
     CDS             complement(2847..3716)
                     /gene="licA"
                     /locus_tag="VVR43_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU6150164.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKITPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            complement(3733..4755)
                     /locus_tag="VVR43_001852"
     CDS             complement(3733..4755)
                     /locus_tag="VVR43_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU6150165.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4760..5467)
                     /locus_tag="VVR43_001853"
     CDS             complement(4760..5467)
                     /locus_tag="VVR43_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU6150166.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5803..7290
                     /gene="tacF"
                     /locus_tag="VVR43_001854"
     CDS             5803..7290
                     /gene="tacF"
                     /locus_tag="VVR43_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU6150167.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFMYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7300..8103
                     /locus_tag="VVR43_001855"
     CDS             7300..8103
                     /locus_tag="VVR43_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU6150168.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8105..8914
                     /locus_tag="VVR43_001856"
     CDS             8105..8914
                     /locus_tag="VVR43_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU6150169.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHHRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2836 a         1815 c         1516 g         2839 t
ORIGIN      
        1 caattcacta tactttccct tatactcaat gaaaatcaaa gcgcaaacta ggaagctagc
       61 cacaggttgc tcaaagcact gctttgaggt tgtagataag actgacgaag tcagctcaaa
      121 atactgtttt gaggttgcag atggaagctg acgtagtttg aagagatttt cgaagagtat
      181 tatatgaaaa aatcctctac tctactaatc cacttagaaa aaacgcatat tatcaagtgt
      241 taaaaacttg ctaatatgcg ttttattatg gaaatgttgg gttcattttc tcttaaaatt
      301 gattttttct tagaattcta gcttaggtca tttttaaaat tcaaattccg caagaacatc
      361 ttgcccactg gtgaccaatt ttgctccttc ttgaatcaaa tgatggcaac cgtctgatag
      421 tccatctaaa atgctaccag gaatagcaaa gacatcgcgt ccttcttcca ttgctcgctc
      481 acaggtaatg agactacctg aacgcatctt agcctctgct acaatcacac cacgacaaag
      541 tccagcaatg atgcgattac gggcaggaaa atgaaatttc agaggttgtt cgccaggtcc
      601 atattcactt agagccagat ggtcattgcc gatgtagtct tgcaagcgtt tattggcttt
      661 aggataaaac acatccagtc ctgttccaat cactgcaatg gtttttccgc cattctgaag
      721 agctgccata tgagctgctg tgtcaatgcc cttggccaga ccactgacaa taaccagttc
      781 attttccaag ccttgaatga ctttttcaac tgacttagct ccctgtttgc tacaagcacg
      841 actgcccacg accgctacct tcgggaattt caggaggtca agatttccct tgtaaaataa
      901 aagtacaggc gcatcatata tttcactcaa atcccaagga taacagtcat ctaaaataga
      961 gaaagatgga aatttttgaa actctttcga caaatgcgca tcgtctatct gaaaataacg
     1021 ttccataaaa acggctggat tacggcaacc tgatatatct gcaatatcac ccaacaaaag
     1081 ctcctgatca acattttcac cgtattctag cactttcaaa atctgttgat tggtcaaacc
     1141 tgattttttt aacttataga tttcatagtt tgtgattttc ataaataact ccatttcttt
     1201 ttctactcat ctatctattc gtaaaagttc gtaaaaaatc aaaaaacatc cgactatttt
     1261 gtcagatgtt ggaatcttta attttcgttt ttaagaattt cttctaattt acgatagtct
     1321 tggacactat cgatctcata aatgctattg ccttctaatt cttcaacata gacatctagc
     1381 tctttgatat tatccttaac catattgtcc caatagagat caacaaattc accacttgca
     1441 taagccttgt cgataaagct gacaatcttt tctgcagttg gagcatccca gaaggataca
     1501 ccactaagga tgcgacctgc cttgctatca acaataatgt cttgaacctt gtagtcatct
     1561 ccatagacca agaaccattc gttggtacaa tcttcacgat aaacactaaa ataagtcgaa
     1621 cgtgtcaaat cattgcggaa catattttta aagagataat tgtcagcatc aataacatag
     1681 ctgttggcca attcttcttt tacaagatag agagagtaaa agttattgta gtcagcgtat
     1741 ttatcattga aaacgaggcg aacaccgtat ttttctttta aataatcgaa ttgttcttta
     1801 agataaccaa cgatgatgat gatgtcattg attccttttt ctttgagaaa ctcaatttgg
     1861 tattcaatca aaggtttttg attaacctga accaaggctt taggggtatt ttcagtcata
     1921 ggacgcaagc gagttcccaa tcccgctgct aagataatgg ctttcacacg aatctccttt
     1981 attctttaat aataatataa actccagcaa tgacgacaag tgacgtcata atggtcagca
     2041 tatctaatga tgttcccaag aaaagagctg cgaacaagac agtccatact acatagctca
     2101 cgttcaagcc tgtagccttg gctggttgca agcgattgat agcgatataa taagccaaat
     2161 aggaaatcat atcaaaggct acaaagacaa tcatgagacc tagcaattgt ccattggcta
     2221 ctgcaacaaa tgactgatga gagaagagca caatcacaag ataggacaag aacgaagtta
     2281 cttgacggat taagagggct tcgatttcac tcaattcact ttccatggca aaagagctaa
     2341 gaacactctc acttccccat gcaatagcac aaaccaaagc acaaagaatc ccaatgtaga
     2401 aagaattaac ctgttcaacc ttataggtct gggcaataat ccctccaata atcaagacaa
     2461 tcccaaatac agtatttttc gaaatcttgt gcttcaaaaa gaagaaagcc aatagaactg
     2521 aaatcgcagg gtaaatagcc gatacagatg aagctaaaga acttccgata tacttaactg
     2581 cataaagatt ggcctgcata ccgatagggc ctgctagcaa ggctcctatg ataacactga
     2641 cattgcgaat atttaagaaa attgagaggc gaactttccc ttcttttacc aagagaaaag
     2701 ctagtaagat aaagatgctc aaaaaatcat gagttgcagc caccacaaag ggtgacaaat
     2761 ctgtaaaaat cgaaaagata taagcactaa ccgttagacc caagccccag aaaatacctg
     2821 agagaaggcc aaaaggaact ccgtttttac ttttcatctg aacctccata agaagccaaa
     2881 cctttaatag ctctttggta acgattcaca ccatagtcac caaaatcttc accttgctct
     2941 tccttataga cagtccatag actccaaata gtatcttgta aaattttata aatagcaatc
     3001 ttttcatgag aaaccggtgt ttggtcactc tcatagtgag ataagaaagt ttcttcctct
     3061 tgggaagtga attcagactc taaaaagagg gcagccaaat cccacattgg atcattcatt
     3121 gatgaatatt cccagtcaat caaataaagt cgtccttgag gtgattcgat aaagttttca
     3181 ggcaccaaat cgatatgaca agattttctg tcaacaccta agtcagccag tcttttctct
     3241 aaggagaaga ctgcatttct aacagattca tagttggcat aaggaatttg ttcttcaatc
     3301 aaggattcgt attttttgat ttcttcaaaa ggagcaaatt ctcctcttaa ttccttagca
     3361 gacgtatgaa tagtttgtaa tattggagta attttgtcga acttggtctt gattgacgtt
     3421 gaatcaagcg taatcgcaga ttcgatatac tcatttactt tgataccagc ttcaatatca
     3481 aaaagataat tttttacatc taagcctaaa tcctttagta gttcaagatt gtacttttca
     3541 tcttgtcgat tgataagctt ttctgtccct ttaccaaaga atttaacaat gtattgctta
     3601 tttgttgttt tggccaaata gttttgattg gtcattccac ccagttgttc aacactgagg
     3661 acttcctctt cttgactaag taaggaagaa attttttctt taatgatttt ctccacaatt
     3721 aacctccagt acttatactt cccacttaaa cactgtttta aaggctgtgt ttaaatcggt
     3781 tgcaaagaca cgatgaatat ctttaatttc tcttacaggt tcttctagat aaaggatatt
     3841 tttaagacga ttggcaaatt tcttgacttc catcatttgg atagcatttt caaaatcaat
     3901 gcgaccagaa cgagatgacc caaccaaaat caagcccttt tctaaggcat cgcgagtatt
     3961 gagattgact ttatattcgc taactcccat catgagaatc gttccctgag gacgaatgta
     4021 gcgaatcaag tcattaatag ctggtccagt accatcacca ccacaacatt caaaagcatg
     4081 gtcaaaggcc aaatcttcag gaatattatc cgtaatatag cattctttgg caaatgagaa
     4141 gagttccaac ttttcccaat gacgaccaat aaccacaatc tctgcttctg gcaaagtata
     4201 gttgataata ttggcaacca caaaagctaa acttccatct ccaataacgg cgatccgctc
     4261 ccgcttgcta tgagcaagag tcaatagacg attcatagcg tgcatgccca cactgacaaa
     4321 ctctgtaatg gctgcaaccg tatcttcaat agcatcataa gccaccacac gatctttagg
     4381 gagagaaaca aactctctca taaagccatc aaatccacta gacaagaaat gggtccctgt
     4441 catgtagttt tcatagaatt cttcatcact ctgcatagga gactgattgg gaatcatgac
     4501 aactttttga ccaacctcgt aggttccggt cgggtcagaa atgacggttc cacatgactc
     4561 gtgaatcatt gccattggaa gctttttatt caaaatcttg ggatcacgtt ttccctgata
     4621 gtaacgctga tccgcatgac agacagccat gtagttggga cggataagga tatgattctc
     4681 ttggtcaata gcctcttcct gatatttgac attgataaac ttaggcttag ttagttgata
     4741 aatttgatta atcattttac tagtctttct caatcatact ttttgcaatc ttcaaatctg
     4801 ttacggttgt aatcttcaga tttgagtatt cacctttggc caaggccaca tcttttcctt
     4861 tgatcacaaa gattttacat gcatctgtca agatttcctt ctcttcatca gaaagagatc
     4921 cataaaggtc catgaagtcc ttgcaacgga atgtttgagg tgtttgtcct tgataaaggt
     4981 gagcacgatt tggaatatct gtaataaatt gaccattggt actttcaacg atagtatcaa
     5041 ccgcttctac cactgtgtcc actgcgtcat gattttgggc aagttggata ttgtcctgaa
     5101 tcatgcgaag tgtaataaat ggacgaacag aatcgtgggt aacaacgata tcctctggag
     5161 taagcggacg ataagcatca atggcttcaa tgattttctt aatacttgta ttgcggtcag
     5221 caccaccctt tgtaatgatg atacgttcct tataaagagg aagatattta tctacaagat
     5281 cttctgcatg agaaacccag tctccatgaa caccaactac aattttttca atacttggct
     5341 ccaagacaaa tttttcaatt gtatgaatca aaataggtcg atcacctagc tctaaaaatt
     5401 gttttggcaa gttactgatc cccatgcgtg tgccagttcc accggcaaga attcctgcat
     5461 aaatcatcta ttttctcctt tgtcttacta aaaaaactta ttctctctat tataccacaa
     5521 tctagtccta tcataaaaga aatactggtc ctccccttct agaataggag aattatgcag
     5581 ttttattatt caaagaaact agtccatttc tagtaatgac taggaattct gtagcaatta
     5641 ctaataaatg gctgcgaaat tttagagtcc ttcagaataa tatactttcc ttaaagaaaa
     5701 cttaaaactt aagatttgaa acttcaaagt gattacttga cttactgccc ttcatttctt
     5761 attagctaac tttatgatat aatgaaaaac gaggtaaatt gaatgaaaag tataaaatta
     5821 aatgctctat cttacatggg aattcgtgtc ttgaatatta tttttcccat cctaactgga
     5881 acctatgtcg cgcgtgtctt ggaccgaact gactatggtt acttcaactc agtcgacact
     5941 attttgtcat ttttcttgcc ctttgcaact tatggtgtct ataactacgg tttaagggct
     6001 atcagtaatg tcaaggataa caaaaaagat cttaacagaa ccttttctag tcttttttat
     6061 ttgtgcatcg cttgtacgat tttgaccact gctgtctata tcctagccta tcctctcttc
     6121 tttactgata atccaatcgt caaaaaggtc taccttgtta tggggattca actcattgcc
     6181 cagatttttt caatcgaatg ggtcaatgaa gctctggaaa attacagttt tctcttttac
     6241 aaaactgcct tcatccgtat cctgatgctg gtctctattt tcttatttgt taaaaatgaa
     6301 cacgatattg ttgtctatac acttgtgatg agtttatcga cgctgattaa ctacctgatt
     6361 agttattttt ggattaaaag agacatcaaa cttgttaaaa ttcacctaag tgattttaaa
     6421 ccactctttc tccctctgac agccatgtta gtctttgcca atgccaatat gctcttcact
     6481 tttttagatc gcctcttcct cgttaaaaca gggattgatg tcaacgttag ttactatacc
     6541 atagctcagc gaattgtgac cgttatagct ggggttgtaa caggtgcaat tggagtgagt
     6601 gtgcctcgtc tcagttacta tctggggaaa ggagacaaag aagcctatgt ttctctggtt
     6661 aatagaggta gtcgaatctt taacttcttt atcattccac tgagttttgg actcatggtt
     6721 ttaggaccaa atgccatcct actttacggt agtgaaaaat atatcggagg cggcatcttg
     6781 acctctctct tcgcttttcg tacgattatc ctggccttag ataccattct tggttcccaa
     6841 attctcttta ccaatggcta tgaaaaacgt atcacagtct atacagtctt tgctgggcta
     6901 ctcaatttgg gcttgaatag tctcctcttt ttcaaccata tcgtggctcc tgaatactac
     6961 ttactgacaa ctatgttatc agagacttct ctacttgttt tctatatcat tttcatccat
     7021 agaaaacaac tcatccactt gggacatatc tttagctata ctgttcgata ctctctcttt
     7081 tcactttcct ttgtagcaat ttatttcctg attaatttca tgtatcctgt ggatatggtc
     7141 attaatttgc catttttgat taatactggt ttgattgtct tgctatcagc tatctcttat
     7201 attagtctac ttgtcttcac aaaagatagc attttctatg aatttttaaa ccatgtccta
     7261 gccttaaaaa ataaatttaa aaaatcatag gagtttaaaa tgaaacaact aaccgttgaa
     7321 gatgccaaac aaattgaatt agaaattttg gattatattg atactctctg taaaaagcac
     7381 aatatcaact atattattaa ctacggtact ctgattgggg cggttcgaca tgagggcttt
     7441 atcccttggg acgacgatat tgatctgtcc atgcctagag aagactacca acgatttatt
     7501 aacatttttc aaaaggaaaa aagcaagtat aagctcctat ccttagaaac tgataagaac
     7561 tactttaaca actttatcaa gataaccgac agtacgacta aaattattga tactcgaaat
     7621 acaaaaacct atgagtctgg tatctttatc gatattttcc ctatagatcg ctttgatgat
     7681 cctaaggtca ttgatacttg ttataaactg gaaagcttca aactgctgtc tttcagtaaa
     7741 cataaaaata ttgtctataa ggatagcctt ttaaaagatt ggatacgaac agccttttgg
     7801 ttgctccttc gaccagtttc tcctcgttat tttgcaaata aaatcgagaa agaaattcaa
     7861 aaatatagtc gtgaaaatgg gcagtatatg gcttttatcc cttcaaaatt taaggaaaag
     7921 gaagtcttcc caagtggtac ctttgataaa acaatcgatt taccctttga gaatttaagc
     7981 cttcctgcac ctgaaaaatt tgatactatt ttgacacaat tttatggaga ttatatgacc
     8041 ctaccaccag aagaaaaacg cttctacagt catgaatttc acgcttataa attggaggat
     8101 taggatgcaa tatttagaaa aaaaagaaat taaagaaatt caactagccc tgctggacta
     8161 tattgatgag acttgtaaga aacatgatat tccttatttt ctcagttatg gaaccatgct
     8221 tggagccatc cgccacaaag gtatgattcc ttgggatgat gatattgata tttcccttta
     8281 tcgtgaggat tatgagcgtt tactgaagat tattgaagaa gaaaatcacc atcgctacaa
     8341 ggttctttcc tacgatacat cttcttggta cttccataat ttcgcatcga ttttggacac
     8401 ttctactgtt atagaagacc atgttaagta caagcgtcat gataccagcc ttttcatcga
     8461 tgtcttccca attgatcgat ttacagactt gagcattgtc gacaagagct ataagtatgt
     8521 ggcccttcgt caactagctt atatcaaaaa atcacgagca gttcacggtg atagcaaact
     8581 aaaagatttt cttagattat gtagctggta cgctctccga tttgtcaatc ctcgctactt
     8641 ttacaagaaa attgatcaac tagtcaaaaa tgctgtaacc aacactcctc aatatgaagg
     8701 aggagttggg atcggtaagg aagggatgaa agaaatcttc ccagttgata cctttaaaga
     8761 actgatttta actgagtttg agggccgtat gttgcctgtt cccaaaaaat atgaccaatt
     8821 tttaacccag atgtatggcg attatatgac accaccatca aaagaaatgc aagagtggta
     8881 tagtcatagc attaaagctt atcgcaaaaa ctgattgagg gggattatac aaactactaa
     8941 gatagaggtt attcaaaaac ataattttag tagaaaatga aatacatatt cccacaataa
     9001 aacgca
//
LOCUS       DAVHSY010000057         8796 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.058, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000057 DAVHSY010000000
VERSION     DAVHSY010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8796
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.058"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..382
                     /locus_tag="VVR43_001857"
     CDS             <1..382
                     /locus_tag="VVR43_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU6150170.1"
                     /translation="KIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIVGEYE
                     DAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIMQDYG
                     VNLICVEDGIDSSKDAGKLMISVL"
     gene            386..1669
                     /locus_tag="VVR43_001858"
     CDS             386..1669
                     /locus_tag="VVR43_001858"
                     /inference="COORDINATES: protein motif:HMM:NF019149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU6150171.1"
                     /translation="MAEIERENIRIQTMEGRIQKAREGKWNGGFAPYGYKLEDGKLFI
                     NEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNGKNPLFDAGLIRKILKN
                     PVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAIVSDEVWQAAQVKLKSQ
                     AKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKDGTKYKDFYYYGCKHRQ
                     MIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEKINMKVDTSEIEKEIDN
                     YQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYRMYDKIDELESSLIDAK
                     AKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISALISEIQVYEEKQSNGQW
                     LKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            1937..2503
                     /locus_tag="VVR43_001859"
     CDS             1937..2503
                     /locus_tag="VVR43_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150172.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSRFMFDPGENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            2825..3013
                     /locus_tag="VVR43_001860"
     CDS             2825..3013
                     /locus_tag="VVR43_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU6150173.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            3075..3833
                     /locus_tag="VVR43_001861"
     CDS             3075..3833
                     /locus_tag="VVR43_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU6150174.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     ISEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKSYFEKNEIFKIQQDVIF"
     gene            3891..4745
                     /locus_tag="VVR43_001862"
     CDS             3891..4745
                     /locus_tag="VVR43_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU6150175.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMCISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            4857..5741
                     /locus_tag="VVR43_001863"
     CDS             4857..5741
                     /locus_tag="VVR43_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU6150176.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            5904..7643
                     /locus_tag="VVR43_001864"
                     /pseudo
     CDS             5904..7643
                     /locus_tag="VVR43_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
     gene            7918..8220
                     /locus_tag="VVR43_001865"
     CDS             7918..8220
                     /locus_tag="VVR43_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150177.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKLVSINE"
     gene            8276..8704
                     /locus_tag="VVR43_001866"
     CDS             8276..8704
                     /locus_tag="VVR43_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6150178.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
BASE COUNT         3062 a         1229 c         1879 g         2626 t
ORIGIN      
        1 aaaaataaaa gtatacctct atacacgagt atctacgtca atacagatag aggggtattc
       61 gttagaggca caaaaatcac gaatgaaagc ttttgctatt tacaacgatt atgaaattgt
      121 tggagagtat gaagatgccg ggaagtctgg caagtctatt gaaggtagaa tacagttcaa
      181 tcgaatgatg gaagatataa aatctggaaa agatggagta tcttttgttc ttgtgtttaa
      241 gttatcaaga tttgcaagaa atgccgctga tgttctttct acacttcaga taatgcagga
      301 ttatggagtt aatcttatct gcgttgaaga tggcattgat tcatctaaag atgctgggaa
      361 actaatgatt tctgttttat aagctgtggc tgaaatagaa agagaaaaca tccgtattca
      421 aacaatggaa ggtcgcattc aaaaagcaag ggaaggaaaa tggaatggtg gctttgctcc
      481 gtatggatat aaacttgaag acggcaagct gtttataaat gaggaagagg cagttgcaat
      541 aagaacgatt ttcgaccagt atgtaaatac tacgatagga gctaatggga tatctaaata
      601 cttagagaat catggaatta gaaaaatccc aagacagaat ggtaagaatc ctttgtttga
      661 tgcaggtctt ataagaaaga tattaaagaa tcctgtatat aatgggaaaa tagcatttgg
      721 aagaagaact ttagaaaaag ttcatggtac aagaaatgaa tataagcagg ttgaacaaga
      781 tgaatatcta atatctgaag ggatacatga agctatagtt tccgatgaag tttggcaagc
      841 tgctcaggtt aagctaaaat ctcaagcaaa gaaatatgag catgtgaata aaggaaaaga
      901 tacacgcaca cacttgcttt ctggaattgt aaaatgcccg atatgtggag tgggaatgtt
      961 tgggaacaag tgtatcaaga aaaagaaaga tggcacaaag tataaagatt tttattacta
     1021 tggttgtaaa cataggcaga tgataagagg tcataagtgt acattcagta agcaaattag
     1081 agaagaattg ttagatgatg ctgttgcaga ggtgattgtc aagatagtaa gtaatccgaa
     1141 atttgcttct atgatgcaag aaaaaatcaa catgaaggtg gatacctctg aaatagaaaa
     1201 agaaatagat aattaccaaa aggaattgag aaagagtcat tctacaaagt ttaagctaat
     1261 tgaggaaata gataatttag atgttgaaga taagcattat aagagaagga aacaggattt
     1321 agatgataga ctatatcgta tgtatgacaa aatagatgaa ttagaatcat cactaattga
     1381 tgcgaaagca aagaaacaga ctattgaagc tgaaaagctt acaggagata acatatataa
     1441 ggttctgatc tattttgata agctctataa agtcatgaat gatgtagagc gtaggcagtt
     1501 aatttcagct ttgatttctg aaattcaagt ttatgaagaa aaacaatcta acggacaatg
     1561 gctaaaatcc attactttta agctaccaat tatagaagaa aatctcaaca taggtttgga
     1621 caatgatgaa caagttgaat gtgtaagttt attagagaaa cgtagttaat cctcaaaagg
     1681 ttccccgaac cttttgagtc ccactgacgc atcacgctga ggcggtatca ctgcttgtac
     1741 gagttgaagc atcagcaaag taaaagtaga tgttcagcca atgcgacgag gtgagaccga
     1801 aggtcgataa ggtgtgttct gggtatagga ctcgtaaagt aagtaggaaa tatgatgaga
     1861 tgatacagag agcctgaatt ggtcaggtga cgtgcttatt tacattagcc tgataatgaa
     1921 aatggagaga ttatcgatgg ttatattgga attgtaccaa aatgattatt ctaaagattt
     1981 agtagcattt gattccatag aagatgggaa agcctttgta gctcaaatcc cgggatacac
     2041 tctggaaaca gaagatggtt ttgaagtgga gtattttaat cctaaaaaca taccggatta
     2101 tatggaaatt atttttaacg gaaatattgt tcctttatct agatttatgt tcgatcctgg
     2161 ggaaaatgta aacattattt ggaaagagat ttcaaattta tccctcaaaa atgatagagt
     2221 gatcgaagga tattcaaaaa ttgatgcata tgtcgttaac aaccatgaag ttaaagccta
     2281 tgtcgaaaca agagaaacga actatcgtaa agcaaaagac ttcttagaaa gccgcggata
     2341 tgaaatcgac agaagctttt tcggaagtga agacggtgaa gcgattcttt acagaaaaaa
     2401 agggatcgaa gtttggcatt tcttgtgtca cttagaccca atgtttgtag agattgaaga
     2461 tgtagaagga tatgttaaag aagaagttgg agagattcaa tagtcaacca aagttccttg
     2521 tgagtatata cctttgctag taaaagagtc aaaacgttat aacgaagggg gggaagaaaa
     2581 cccttgagtg taagtctttt tcttgtttag agggaaagta ttagagtagc cgctcataat
     2641 ttatactaga tttgataact gatttgagac agattttatt tctataaata ttgtgaaaat
     2701 tttttaatac caaagattta aagttactgt gttaaaaatc ctctccactt ttaaactaat
     2761 gtattataaa agccagttga cacaagtgtt acacctgtga tagaattaac ttgaggtgat
     2821 gaaaatggca accgataaaa atagaataat gattagcttg gatgataaaa atctagagaa
     2881 acttgaaaat ttagtagaag atgctagaga tagaagggga atgcgactaa caaagtccca
     2941 ggttattgaa ttactcctaa ataccgttga ttatttcgat gatattatgg gggctattta
     3001 ctcaaaaaaa taagagcaaa attgctatta ttttttacaa attggtgtaa cactagtgat
     3061 ataggagtga tgaaatggtt gtttatatta gacaaagtaa attaccaagt gaggtttcaa
     3121 ttaataaata caatgctcaa gtaggtgcct acttacaagg agaagaagtt attttatatc
     3181 aatctttttc tgaaataaaa gagttaataa gtgaagatat agttgtagat tatataatgg
     3241 agactagagc attactaaaa atgatgggct taaacgttcc ggtttatgac tatcctattg
     3301 agcttaaaga gttttatggt cgaaagattt atgctggtat tttaggagag attgtgaata
     3361 tacctgataa ttggggaaaa tttattaagc ctaaagctgg ttcaaaagtc tttactggaa
     3421 gagttgttaa tggaacccat gatttaatag gtattggtct acctttcgac tatcctatat
     3481 ggattagtga ggttgtagaa ttcatagctg aatggcgttg ttttgtgtta gatggtcgcg
     3541 tattagatgt tcgaccctat acaggtgatt atcatgcaca atttgatgca agtgtaattg
     3601 atgaagcgat atcatgttgg aaagatgcgc caatagctta tggactagat atcggtgtta
     3661 ctcgcgatgg cagaacactt gttgttgaag taaatgatgg ttatgcattg ggaaattatg
     3721 gcctatctcc tttaaaatca atcaattttc atagagctag gtggaaagaa atggtaaaat
     3781 cctattttga aaaaaatgaa atttttaaaa tccaacagga tgttattttc taaaataaat
     3841 atggtagata accaatataa aaagcatcaa aatgaacaag gaggaatctg atgcttggag
     3901 caattattgg agatattgtc ggttctgttt acgaatggaa caatatcaaa acaaaggact
     3961 ttcctttatt tcggaaggac tgctttttta cagatgacac ggttatgacc tgtgctgttg
     4021 cagaagcaat tatgaatggt ggacaaaaag acgatttcat tgacgcgatg aagaaatatg
     4081 gcagaatgta tccgaatgct gattacggtg ctcggtttaa tgcatggcta aacagcgata
     4141 accgtgagcc ttataatagc tttgggaatg gatcagctat gtgtatttct ccatgtgctt
     4201 ggatcatgga ctgtggtttt tatgcgaaaa ctggtatgtg gccatcatct agaggactta
     4261 cgagtctttc tgcagaggta actcataatc atccagaagg tgtcaaaggc gctatggcta
     4321 cagctgatgc tatctttcta tgtcgttttt actttggtgg ttattgtaga gagtacgagc
     4381 aatcaattaa cgacaatcct acagagtgta aaagacgaat taaggattat atagaaaaag
     4441 aatacgatta caatctatct caaactttag atgaaatccg tcctaactat cgttttaacg
     4501 aaacatgtca ggaaactgtc cctcaagcca ttatcgcctt tcttgaaagt agagacttcg
     4561 aagatgcgat aagaaatgcc atctcacttg gtggcgacag tgatactctc gcagcaatca
     4621 cttgtaacat agcagaggca gcttacggta ttcctgattg gatcaaggat aaggcctatt
     4681 cttacttgga tgaaccctta aaggatgtag ttaggcgatg ggaaaataga ataaaagcgt
     4741 attaatctcc agtacgtcag atttctcttt tctgtatttt cattgtataa taggattaca
     4801 tttacttgca tacgacgaaa tgtaaacatt tctgtttaaa attaaggata aaatcaatga
     4861 aaaaagcaat ggtaattatc aaccctactt ctggtggcga gaaggctttg gattacaaag
     4921 aaaagctgga gaataaagca aaagaatact ttgaatatgt tgaaaccaaa attaccgaaa
     4981 aagcgctgga tgcaacacat tttgctgaag aagcttctcg tgagcagtat gatgcagtgg
     5041 ttgtgtttgg tggagatgga actgtcaatg aagtcatttc aggtattgat gagagagact
     5101 acattcctaa gttagggatt atcccaggcg gtacgggtaa cctcattaca aaacttttgg
     5161 aaatcaatca agacatcgat ggcgcaattg acgaactgga ttttgattta accaataaga
     5221 ttgatatcgg taaagcaaat gacaactatt ttggttatat ctttagtatc ggttctctgc
     5281 ctgaggcgat tcacaatgtt gaaatagagg acaaaacaaa attcggtatt ttaacctatg
     5341 ctgtaaatac catgaagtct gtcatgacag atcaggtctt taacattaag gttgagacag
     5401 aaaatggaaa ttatgttggt gaagctagcc atgttttggt ccttttgaca aattacttcg
     5461 ctgataagaa aatctttgaa gaaaacaagg acggctatgc caacattttg attctgaaag
     5521 atgcctctat attctccaaa ttatccgtca ttcctgattt attaaaaggg gatgttatcg
     5581 caaatgataa tatcgagtat atcaaagcgc gtaatattaa aatctcttca gatagtgaat
     5641 tggagtcaga tgttgacgga gataaatcag ataacctacc tgtagaaatc aaagtcctag
     5701 ctcagcgagt agaagtattt tcaaaaccga aagaggatta gtatatagag aaagcctttt
     5761 ttaaggcttt ttgtatactt taaaagatag ttcctttaac aacggacatt ccttgcaaat
     5821 agtttacaaa aatagtatac tggattcatt gagtttgaaa acgtttgcgt aaaatttgaa
     5881 tgaatacttt aggagacaaa ttgatggaat tgagtgctat ttaccatagg cctgagtcgg
     5941 agtatgccta tctttataag gataagaaac tccatattcg aattcgaact aagaaagggg
     6001 acattgaaag catcaacttg cactatgggg acccttttat ctttatggag gagttttatc
     6061 aggatacaaa agaaatggtc aagataactt ctggtacctt atttgaccat tggcaggttg
     6121 aagtgtcagt tgactttgca cgtatccagt atctctttga gctcagagat acagaaggtc
     6181 aaaatatttt gtatggcgat aaagggtgtg tggaaaattc tctagaaaat cttcatgcaa
     6241 ttgggaatgg atttaagttg ccttatcttc atgagattga tgcctgcaag gttcctgact
     6301 gggtttcaaa tacggtatgg tatcagatat ttcctgaaag atttgccaat ggcaatgctc
     6361 tattaaaccc agaagggact ttagactggg attcatctgt cacacctaag agcgatgatt
     6421 tctttggtgg tgatttacag gggattattg atcatatgga ttacttgcaa gacttgggta
     6481 ttactggact atatctttgt cccatctttg aatctacaag caatcacaag tacaatacga
     6541 cagattactt tgaaattgac cgtcattttg gagacaagga gacctttcgg gaactggtgg
     6601 atcaagcgca tcatcgtggc atgaaagtca tgctggatgc ggtatttaat catattggtt
     6661 cgcaatctct tcaatggaaa aatgtcgtca aaaatggtga acagtctgct tataaggatt
     6721 ggttccatat tcaacaattc ccagtgacaa ctgaaaagct agttaataag agagacttac
     6781 cctatcatgt ttttggtttc gaggactata tgcctaagct aaatacagcc aatccagagg
     6841 tcaagaatta tcttttaaag gttgcgactt attggattga agagtttaat atcgatgctt
     6901 ggcgtttgga tgtggctagt gagattgacc atcagttctg gaaggatttt cgtaaggcag
     6961 ttttagctaa aaatcctgat ctttatatcc taggagaagt ctggcataca tctcagcctt
     7021 ggctaaatgg agatgagttc catgccgtca tgaattatcc tttatctgat agtatcaagg
     7081 actatttctt acgaggaatt aagaagacag accagttcat cgatgaaatc aattgagagt
     7141 ctatgtatta caagcagcag atttcagagg tcatgtttaa tctcttggat tcacatgata
     7201 cagagcgaat cctgtggacg gccaatgaag atgttcaact ggttaaatca gccttagcct
     7261 ttctctttta acaaaaagga acaccgtgca tttattacgg aaccgagcta gccttgactg
     7321 gaggaccaga tccagattgt cgtcgttgta tgccttggga acgtgtatca agtgacaatg
     7381 atatgctgaa ctttatgaag aggctgatta agattcggaa atacgcgtca gtaatcattt
     7441 cgcatggcaa gtatagcctt caagaaatca aatctgatct agtagctctg gaatggaaat
     7501 acgaaggatg gatcctcaaa gcaatattca accaatcaac agaagattat cttttagaga
     7561 aagaagcagt agcactagca agcaattgcc aagaattgga gaatcagctt gtcatctctc
     7621 cagatggatt tgtgattttc taaaaactag ttgatgaaga ttatggtaca tttcatatct
     7681 tatatagtat aataaggcta gttactaaac ttgtaaagga gaacttaaat gaattgtaga
     7741 ggacatgaaa caagacaaag aattgttaga gattttgaag tttagcctaa agcacatatt
     7801 aagctgttag caaatcaaca aaaacatagt gatgcaggag caactattga agatgaatat
     7861 tatgtattta tcgctgagag taaaattgat ggcaagaagg aagttattca gtgttgcatg
     7921 ggtgcggcaa gggatttttt agaactaatt aatcacaaag ggctacctct ttttaatccg
     7981 cttgtaggtg attctcatgt aaataataga caagaatatg acaatacagg gagtggaaat
     8041 ttacaacctg aaaagtggaa tgaaactgca aagcagcttt ataatgttat aatgtggttg
     8101 attattttat ggaatgctaa gccggataca cctttattta attttaaaga cgaagtaatt
     8161 aagtataaaa catatgagcc ttttgaaagc agtataaaat tggtatcaat caatgagtaa
     8221 caaagtatca gcatgattcg aaacatttac ttgtaatttg cggaggaaca tcaatatgga
     8281 tggaataaca aaagatttta taaaaacggc taaactaatg aaacaattat ggccccaatt
     8341 gaccgataaa gaagctattg atgaagtaaa aaaatatacg aatggcaaaa atactgcaat
     8401 ctttactgaa gttgaaggtg acacaattgt aggtctagca ctatgttcac tcagatttga
     8461 ttatgttgaa ggttgtaaat atagtcctgt tggattctta gaagggatta ttgttgacga
     8521 ggaatatcgt ttaaaggata ttgctaaaaa tctctgtaca aaatgtgagg aatgggcgaa
     8581 aaataaagga tgtaaggaat ttgcaagtga ctgtacttta acgaatacgg attctataag
     8641 atttcatctc aatattggat ttcaggaggc aaatagaatt attcatttta agaaaaaatt
     8701 ataatttaga aacgtgaata aacttgttta aactttatgt atctttagaa agtgtgttaa
     8761 cttgaaagaa caaatttttt tgatgggtgg gaatcc
//
LOCUS       DAVHSY010000058         8521 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.059, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000058 DAVHSY010000000
VERSION     DAVHSY010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8521
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.059"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(629..937)
                     /locus_tag="VVR43_001867"
     CDS             complement(629..937)
                     /locus_tag="VVR43_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6150179.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(934..1242)
                     /locus_tag="VVR43_001868"
     CDS             complement(934..1242)
                     /locus_tag="VVR43_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6150180.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1247..2542)
                     /locus_tag="VVR43_001869"
     CDS             complement(1247..2542)
                     /locus_tag="VVR43_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6150181.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2560..3969)
                     /locus_tag="VVR43_001870"
     CDS             complement(2560..3969)
                     /locus_tag="VVR43_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU6150182.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKSIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4127..4855
                     /locus_tag="VVR43_001871"
     CDS             4127..4855
                     /locus_tag="VVR43_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6150183.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5315..5509
                     /locus_tag="VVR43_001872"
     CDS             5315..5509
                     /locus_tag="VVR43_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU6150184.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5875..7185)
                     /locus_tag="VVR43_001873"
     CDS             complement(5875..7185)
                     /locus_tag="VVR43_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU6150185.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7422..8294
                     /locus_tag="VVR43_001874"
     CDS             7422..8294
                     /locus_tag="VVR43_001874"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU6150186.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            8425..>8521
                     /locus_tag="VVR43_001875"
     CDS             8425..>8521
                     /locus_tag="VVR43_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU6150187.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISR"
BASE COUNT         2661 a         1491 c         1610 g         2759 t
ORIGIN      
        1 ctgatagagt tgttcacatc ttatttcaat tcactatagt ttaatttaag agtagtattt
       61 actaaggccc aattaaaatc aaagagcaaa ctagaaaacg agtgccattc agctcaaaac
      121 actgatttga gattgcagat aagactagcc ccctcattaa cagatttacg ataaaacgat
      181 gacaaggtgt gttgcttttt gatttctaaa gagtataatg atagatctct ataaaataag
      241 tgcgaaggaa atgagctttt atagtccttt cgttttaaaa tactatctca gatattctta
      301 tatcgacaag aagtttttga gtcattccct catcatacat attaaataaa tagtggctca
      361 ttcaattttt cactagaata ataagctagt atagtaaact gaaataagat ataaacaaat
      421 aaattggagc ttaacatcca tttccagcaa ttttttagaa actacagtgg actattctag
      481 attcaacata ttataaaaac tagagtaaaa gaaaaggatt ggatcttgtg taatgcagga
      541 tccaatcctt tcaatcattt tgtccaactt ttggaggttc ctacaatgta gtcgtcatta
      601 ataaagacag atgggaatga cagtgttcct atttattttg atagagatcg atgaattctt
      661 tagatagcaa ctgaataatc tctgttgaag ccatttggtc ttctgcatgc ataaatagca
      721 aggagaatcc tattttttct ccagtagctt ctttttgtat gagattagag tgaatcttgt
      781 gcgcttctac taaggagtct tccgcttctt caactttaat tttcgcttct tttaaatttc
      841 ctgccttagc tagttggatg gcttcaataa aggatgattt ggctgctcca ctattggcaa
      901 tgagctgaaa acagatatat tccatttctt ctgtcatctt atttctccta tccatgcaag
      961 tgcttgttcc agaacttttg ctccattcat cattccgtaa tcccgcatat caatggtatc
     1021 tacagggata tttcctgcaa tttctttcac agcaagtaac tcataacgaa tttgtggccc
     1081 aattagaatg acatctgctt catggatatt ctttttagct tctgtcattg attttgcttg
     1141 gatagagatt tcaatcccac gttcagtcgc actttgttgc atttttttaa caagcatact
     1201 tgtcgacatt cccgcattac atactaataa aatttgtttc ataatcttaa ccttccattt
     1261 cttgttcaac aactttgtca ttaactttga taaatggaat gtatagaaga actccaagtg
     1321 caaagatgat gaattgaact agaactgctc tcacgtcccc tgctgttgct aaccatgcat
     1381 ttaagaatac tggtgtagtc caaggaactt gtataaatgc aggactcatg aatcctgtaa
     1441 ctgttgctaa gtagctgatt aaaataccaa ggactggaac tgtgataaat ggaatagcta
     1501 atgaaatgtt ataaacgatt gggtaaccga ataatactgg ttcattgata ttgaagatac
     1561 caggtccaaa agataattta gccacgtttt tagagacagc attgcgactc actaagaatg
     1621 ttgctattaa taaacataat gtagatccac taccacccat taaagcgaat gtttgtattt
     1681 gtgataggtt gatgatgtgt ggaatggctt gtccattatt tgctgcagtg atgttttcag
     1741 taatgttaat taatagtaat ggttctagga tggcactgta aataactgct tggtgaatac
     1801 caaatagcca taacatattt cctaaagagt aaataataat gaccccgatt aagcttgtac
     1861 caatatgacg aattggttct tgaataaaga ttgtaatgat tgagattaag ttcattccag
     1921 ttatattgaa taataatgct gaaacaaccc caaataagga gatgacggtc atgactggaa
     1981 gtaatacgct aaatgatcta ctaacagctg gtggaatatt ttcaccaagg ttcatttgta
     2041 aagctttaac atttgataat tcaatgaata attctgttgc aataatcgct acgataaccc
     2101 cggcgaacat tgcgcctgta cctgtgttgt tgaatgaaag aacacctgaa atgtttacag
     2161 catcttttgc tccgtcagga actacagaaa ctgtatttgg catcatcaca attaaagaaa
     2221 ctaatgatag cattgatgct gctaacgggt tttcgaaatc tctgttttta gctaagaaat
     2281 aaccaaccat tacagcaata atcatacctg aaatacttaa agtaccgttt gcaattgtta
     2341 ttccccaata ttggaatctt gttaatgtat ccccttggaa aatccactta aataccgtgt
     2401 tgttcaaaag aacgattaaa cctgccaaaa tatataatgg cattactgtt acgaatgcat
     2461 ctcttagggt ttttaaatga atttggttcc ctagtttacc agcaaaggtg gcaaattggt
     2521 ctataaattt tgagtttttc atatgaatat ctcctctctt tactcctcaa tttctacttc
     2581 aaaaccgtta ttgtcactta ctttgcgata ccatcttcct gagctcttga tggttctctt
     2641 ttgcgtttct aaatcaacgg agataaatcc gtaacgattc ttatatgcat tattccaaga
     2701 ccagcaatca aatgcggtcc aagcgtggta tccaaaacag tgacttccct cttcaatggc
     2761 tttatgtagc catcttaaat gttcttcata aaattcaata cgatacacgt catcgataac
     2821 tccattttca tcgataaacc gtgcttcgtt ttcaacaccc attccgtttt cactgataaa
     2881 ccatgggata ttaccatatt cttccttcac aatcatagca atatcataaa tggatttcgg
     2941 aaaaatttcc caaccacgat atggattcat gcgacgctcc ggccattcat actctttgaa
     3001 gtattggtct ggcatccagg gcgtctgata ttcctcagga tttgcttgtg cttgaacacg
     3061 ttttggatgg tagtagttta ctccaagaaa atcaaccgta tttgatttca tcagttgaag
     3121 ctctttttcg gtatgactcc ataacacgcc atctctctct agctgtttta ccaatctttc
     3181 tgggaaagtt cctttaacag ctggattcaa gaagactttg ttaaagaagt catctgtaaa
     3241 tcgacttgct tctaagtctt ctggagaatt acttcttgga taagcaggtg tcaagtttaa
     3301 aataatccca atctttccat caagttctaa tgagcgatat agttgaatca cttttgcact
     3361 agcaaggttt agattataga tgacttgtac ggcctctttt ccctttcctt ttagatttgg
     3421 ataatggaaa gcatataagt atcctgcttc tggaatgacc attggctcat tgaaagttgt
     3481 ccagtaatga accttatctc caaagcatgt gaaagcagtc ttggcaaact tcacgaataa
     3541 ctccactaca tgtttgcttt cccaaccacc gtatttttga agaagttcca ctggtaaatc
     3601 aaaatgatgt aaattcatca caagatccat ctggttcttt ttagcttctt caatgatggc
     3661 attgtagaaa gcaatacctt ttggatcagg ctcacctgtc tctaaattct tgatgagtcg
     3721 actccattgg atggaagtgc ggaaagaatt aactccaatt tccttcatca agtggaaatc
     3781 ttcggtgtaa gtatgaaaaa agttactggc tacaagaggt ccgacattat cgaaaaaatc
     3841 ttctggatgc gttttgaacc agtagtccat cacattttca tgtacttttc catattgacc
     3901 ttctgtctga ggtccgctag aagctgctcc ccaccaaaac agattaggaa atactaactt
     3961 ttttttcatg ctcaacctcc tttctattat tctatacata aagtatagca taattttaaa
     4021 atttgtctag acatttttaa aaattgttga tacatatctt gtgtttgcct catttcttga
     4081 actttgttat actactatta gaatattata gagagaacca gattaaatga gtacaaaata
     4141 tttatttatt tacaatgaga ttcgtgaaaa gattctttgt aataaatata ccatgaacga
     4201 acaattacct gatgaaatga cattagctaa acagtttgcc tgtagtcgaa tgacgatcaa
     4261 aaaagcttta gacttgttag tttctgaggg cttaattttt agaaaacgtg ggcagggaac
     4321 ctttgttctc tctcgtggca gctcaaaaag aaaattaatc gttccagaaa gagatatccg
     4381 gggactgaca aaaatatctg aagatgctca ttctacaatt gactcgagga ttattcactt
     4441 caaattagaa tttgcaaatg aatttttagc agaaaaacta caggtcgctt tgcagagtcc
     4501 agtttataat atttaccgcc tgcgtattat tgacggtaaa ccttatgttc tggaacaaac
     4561 ttatatgagt accgatgtta ttccaggtat tactgaagat attttacaaa aatcgattta
     4621 caattacatt gaaggaaagt taggattgca tattgccagt gctacaaaaa tcttacgagc
     4681 ttcttctagt tcagaaaatg agcaacatta cttgcagctc cttccaacgg aaccggtatt
     4741 tgaagtagaa caagtggctt atttggataa cggaactccg tttgagtact cgattagtcg
     4801 tcatcgctat gatttatttg aatttaattc ttttgcatta cgacattcct cctaggagaa
     4861 aatgtgaaaa tgaagccaat cttttacaga ctctagttta agaaaaattt aaaacagggc
     4921 aagaaggtcc catctatgct taaatggttt ctcttttcta aataagatgg ctttaaaaga
     4981 gtgatcgttt tatccatcat gttgaaaaat atcttcgtat agcttataga gtaggtactg
     5041 aaattgttca cctgatctac ttcttatagt tatttagttt taaatagtgt ttcaaatatt
     5101 cttacactga cgagaagttt ttgagtcttt tcttgtaaca catatagtat actgaggtta
     5161 gaatagtaga ctgtgacttc taacaaattg ctagaaatga atttcaatct cccaatttat
     5221 ttgttcaaat attgttttaa tatattgaat aaattctgaa tcataatcat ttaaaaaaat
     5281 tttatttttt tatttttcat tacgaataat atagatgaag gggaaagagt atgaaaacag
     5341 aactgtttct tttgctatta gttcaaaagg agaaaaaatg aaagtagaaa atatttcgta
     5401 tagggtggat catcgtatat tgtttgataa tatttctttt gatacttcga gttcaggcgt
     5461 gacattaatt actggtaaaa atggtacagg aaagtcaact ttactatagt agattgaaac
     5521 tagaatagta cacatctact tctaaaatat tgttagaaat cgatttgact atcctgatct
     5581 atttgtcctg ttcttatttc atttcactat atctcaaatt gagtatgacg aagtgcgctc
     5641 ccatgtcctg ggaacgcact ttcttcatat ttttcatatt cttgaatcca tcgataaaga
     5701 ctattgggat gaatttttaa agttgaacta atcattttta caggatgaga tttacagcag
     5761 agagtttgaa ggctttatca aaggtttttc ttggcataat gacttttcct cgtttccact
     5821 taattttgtg tctactttat tataccaagt ccacccttaa gttagataat aaatctaact
     5881 taaggaagct agaaggatga gaatccaggt ggtcaagagt cccaaactta agctgatggg
     5941 gacacccaga ataatttgct ttttgaaggc aaggccacgt tcctctatat tgggaagtga
     6001 gagttgaatg agagaaccag ctgatgaaaa gggtgagata ttagtagata gagcgccaat
     6061 aacggtggct gttgtgagta agtgaatatc aatctgagga ttttgagcac tgatgatagc
     6121 aatgatggga aagagggctg gagctacaac ggatagggtg gaactaaaga gtgacatcac
     6181 tccggctatc acacaaaaga acagaggtaa ccagaaatga ggaatggttg ttgtcatgag
     6241 gtgccctatc agtgtgacta aacctgactt gaccgctaga gacattagta agctcatgcc
     6301 gcagagcatg ataattgtag cccagggaac cttagctaaa atggcttctt gcttccctaa
     6361 tttgagcctt aaggcgaggc agaccatgag tattgagaca aagccaatat caaatgtttt
     6421 ttgataagta gctatccagg cgatgtttgg gaaaatgaga tgcaacaagg gaaaaagcca
     6481 aaccaaaacc atgctgctga tcatgagcaa ggtggtttgt ctttgaacct tgctgaggag
     6541 tggtggttgg tcaatagtca aggatgagtt tgttcttccc ttactatagt gactgtaaca
     6601 ggataataaa agcaagacga tgagtgggta gataatgctg acgataaaga tatgattgcc
     6661 aagtgaaaaa gcttgctctt cccatcccat ttgcttaaac aggccttgaa agacaatgcc
     6721 tgagctactg gttatcaaat tagcccctcc tgaagctccc caattgacgg cttgagctcc
     6781 aatcaaaggg tgtttgtccg ctttttgaca gagggtaatc gctagaggac agcaaacggc
     6841 catagtagtg aaaaatccag cacctaaagc agacaaaagg gttgccatca ggtataaaat
     6901 catgtagagg gcgttagggt gggtgcgtgt gcggtagaga atgtgttgag ccaaaacatc
     6961 aagagtaccg ttagttgttg caacgttata aaagagagag acgctaaaaa tggtaaaaaa
     7021 gagtgaggtt ggccaaaaat gaagaagttc tttggggctt aatcccatga gagtggttgc
     7081 gatgaggtaa gaaaaagcaa tagccagcag gccaatattg attttggtgc ggtaaccaat
     7141 tccaatggct agagcaatgg cgctaatcat tattaaatga atcattgaat tgtcctttca
     7201 gttagaatat ggaaataggt tggcaatttt ggcgctcaaa agaccacctg tttcctattg
     7261 gtacttgact attatacaca aaaaaaatac aattgtcttg acaattgtat tgacacttgt
     7321 tagaattaaa aatgaggtat tcaggcttgt gatttcctat ggaagttaat agtaattgcc
     7381 tctagtgctt acaagtgata ttaaaaatag aggacttagt gatgtcaatc atttcaactg
     7441 atttaacccc ttttcaaata gatgatacat tgaaagcagc cttgcgagaa gatgttcatt
     7501 ccgaagatta cagtaccaat gccatttttg atcatcatgg ccaagccaag gtgtcgcttt
     7561 ttgccaagga agctggtgtt ttagcgggac taaccgtttt tcaaagggtt tttaccctat
     7621 ttgatgccga ggtgaccttc cagaatcctc atcaatttaa ggatggggat cgtttgacta
     7681 gtggcgattt ggttttagaa atcataggct cggtgagaag tctcttaaca tgtgaacgcg
     7741 ttgccttgaa ttttttacaa catttatcag ggattgcttc gatgacagct gcttatgtag
     7801 aagccttagg cgatgattgc attaaggtat ttgatactcg aaaaactact cctaatttac
     7861 gtctttttga gaaatatgcc gtgagagttg gcggtggcta taatcatcgc tttaatttat
     7921 cagatgctat catgctaaaa gacaatcaca ttgcggcagt aggtagtgtt cagaaggcaa
     7981 ttgctcaagc gcgtgcctat gccccttttg tgaaaatggt cgaggtggaa gtggaaagcc
     8041 ttgctgctgc cgaagaagct gcggcggcgg gtgctgatat tatcatgttg gataatatgt
     8101 cattggaaca gattgaacag gccattaccc taattgcagg acgttctcgg attgaatgtt
     8161 ctggaaatat tgatatgacc actattagcc gttttcgtgg tttagcgatt gattacgtct
     8221 ccagtggtag tttaacccat agtgctaaga gtcttgattt ttccatgaag ggtttaacct
     8281 accttgatgt ctaagttgta aaataaacta actttttaaa ggatgtcttt cctctagaac
     8341 gagttttatg tcagatagtt taaacgcctc ttcaaatata gtaaaatgaa ccaaaaatag
     8401 tacacaatgt ggtataatct tcttatggca tattcaatag attttcgtaa aaaagttctc
     8461 tcttattgtg agcgaacagg tagtataaca gaagcatcac acgttttcca aatctcacgt
     8521 a
//
LOCUS       DAVHSY010000059         8444 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.060, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000059 DAVHSY010000000
VERSION     DAVHSY010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8444
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.060"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(<1..1398)
                     /locus_tag="VVR43_001876"
     CDS             complement(<1..1398)
                     /locus_tag="VVR43_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU6150188.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSTNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRENLSNLRTYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGNHYHF
                     IPYSQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSDREFYNK"
     gene            complement(1651..3384)
                     /gene="ptsP"
                     /locus_tag="VVR43_001877"
     CDS             complement(1651..3384)
                     /gene="ptsP"
                     /locus_tag="VVR43_001877"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU6150189.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQRAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(3390..3653)
                     /locus_tag="VVR43_001878"
     CDS             complement(3390..3653)
                     /locus_tag="VVR43_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU6150190.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            4004..4222
                     /gene="nrdH"
                     /locus_tag="VVR43_001879"
     CDS             4004..4222
                     /gene="nrdH"
                     /locus_tag="VVR43_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU6150191.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            4303..6462
                     /gene="nrdE"
                     /locus_tag="VVR43_001880"
     CDS             4303..6462
                     /gene="nrdE"
                     /locus_tag="VVR43_001880"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU6150192.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            6650..7612
                     /gene="nrdF"
                     /locus_tag="VVR43_001881"
     CDS             6650..7612
                     /gene="nrdF"
                     /locus_tag="VVR43_001881"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU6150193.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSADD
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEVMQDDDYNYGLD"
     gene            7794..>8444
                     /locus_tag="VVR43_001882"
     CDS             7794..>8444
                     /locus_tag="VVR43_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6150194.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFD"
BASE COUNT         2470 a         1761 c         1608 g         2605 t
ORIGIN      
        1 cttattgtaa aattctcgat cactagatgg gaggtcagtt ttcttagctc ctagcttatg
       61 agataaactt tcctgcttgg ccagtttgct atcaatgcct gctgctgttt ctgctgaaag
      121 atccttggct gggatataac gagaaactcc attctcctca aagacataac catcgcctac
      181 ttttcgaaca gcttctttga ccaatttctc atcaattgga ttgcttggag ctggttgagg
      241 atttggtgca ggttgcagac ttggactagg ttccggagtc gattgtggac ttggttgttc
      301 tggtcttgaa tctggtaccc aatggtttga acgataacga aggggaataa tacgagcaat
      361 tcgtttttcc aattcagaca tttgagagta agggataaag tggtaatggt taccatgagg
      421 gacagctaca cctctggcgg ttcgacttgt gatttgcgct gggtcgaaaa taaggccatc
      481 agattccaca tggcgttgac tcaaaggcag tttgtagagc tgtttcaaga gactatcaat
      541 gtcattactt tgacttgctt gactgttagt gttgctgttg ttgcttgtgt tagtatttgt
      601 agttcctgga ttgcttacag aaggtaccca gtttgttctt ggagtgttat cgctattttg
      661 tcggcgatag gttcttaaat ttgacagatt ttcccgacca gataggaagg cttctgcagc
      721 agccaactcg ctagctgata actcattctt aggaatgtaa tggtaatgat ctccatgagg
      781 aacgatataa gcatcaccag tgtcctcaat gatatcagat gcattgaaga tatacccatc
      841 atctgtggtg tagcgtccct gtgaacgtgc aaaggctacc gcaccatcgt ttgttgaagt
      901 ccctccttca cgatgctgac tatgttcttg tttttgtcga ttgatttcct cttttgtacg
      961 gacgttatcc gcgtgggcag catccttaag gtaaacatag tattttccat ctaccttgat
     1021 aacatatcca cccttgacct cattaacaat atcctcatct tttagcttat agtttggatc
     1081 tttcatgagt aattcttcac tgaaaatcgc atcataagga accttcccat tgtaataatg
     1141 atagtggtcg ccatgtgaag tgacatagcc ttggtctgtt atcttgatga cgatttgctc
     1201 agcattgatt ccttcacgct tgctaacctc atcaggagtc aagttctccg ttttttgcgt
     1261 cgcttgtttt ccatctatat aggaaacacg attattttcc ttaaccgttc tagcttgata
     1321 cagtcccaac tcgtaagaac aaacacttaa aatcaaagct gccgcagaac caacaaggta
     1381 tttcttatta attttcatcg aaactctctt tctatttgat atttctagtt gcaattcatt
     1441 tctaaattgc agaaactcct ctctattact taactggtta atagtttact cctaaatctc
     1501 caacttgtca agaattttat gaaccattta agtatttttt gttctgacca ctactttttc
     1561 aaggttggac tttctataag aaagattttc ttgaaaattt ttttaaaata tcaaaaaaat
     1621 ccctgtaact gagttgcagg gacttttcga ttaatcaaaa ttaacgtatt ctttttgaag
     1681 ttcaagaact tcttccattg ttgagcattc tgtaagggca cggtttgcgt actcttccat
     1741 cttagctgtg tcgagtttct tcatcaagct gcgtgtacga agtacagatg ttgctgacat
     1801 agagaactca tccaagccca ttccgacaag aagtggaaca gctcgttggt caccagccat
     1861 ctcaccacac ataccagccc atttaccttc agcgtgagct gctttgatca cattgttaat
     1921 caagcgtagg attgatgggt tgtatggttg gtaaaggtat gaaacttgtt cgttcatacg
     1981 gtctgctgcc attgtatatt ggatcaagtc gtttgtacca attgagaaga agtcaacttc
     2041 tttagcaaat tggtctgcaa gcatagccgc tgcaggaatc tcgatcatga taccaacttg
     2101 gatgttatcc gcaactgcaa caccttcagc aagaaggttt gctttttctt catcaaagac
     2161 tgctttcgct gcacggaatt ctttcaagag cgcaaccatt gggaacatga tacgcaattg
     2221 accgtgaaca gacgcacgaa gaagagcacg gatttgtgtg cggaacatag catctccagt
     2281 ctcagagata gagatacgaa gagcacggaa tccaaggaat gggttcattt cgtgaggcat
     2341 atcgaagtaa ggaagttcct tatctccacc gatatccatt gtacgaacga caacaggttt
     2401 accgttcatt ccttcaagaa cagccttgta tgcttcatac tgctcatctt cagttgggaa
     2461 gtcttgagaa tccatgtaca agaactctgt acggtaaagt ccaacagctt ctgcaccgtt
     2521 gttgttaaca ccttcaacgt cttttggagt accaatattg gcagccaact cgaagtgttt
     2581 accgtcagca gtcactgttt gagcatcttt caaaagtgcc cattcagctt tttgtttcgc
     2641 ataggcttca ccagctgctt taaattctgc cgcttgttca tctgttgggt tgataatcac
     2701 ttctccagtg atcccgttaa cagcaaggat gtcaccgtct ttaacgattt cagtgatgtt
     2761 gtttgtacct aatacagcag caatttcaag tgtacgtgcc atgatagctg agtggcttgt
     2821 acgtccaccg atgttggtta caaaagcttt tacaaagttt ttgtccaatt gagctgtatc
     2881 tgaaggagtc aagtcatgcg caatcacaat cacttcttca ttgatagaag ctgggtttgg
     2941 caatttttta ccaagaaggt ttgccaatac acgttttgtc acgtcgcgga tatccgctgc
     3001 gcgttcttgc atgtatgggt tgtcttccat gccttcaaag atagtgataa acatatctgt
     3061 aacttctttc agacctgctt ctgcattcac tttcttcgca cggatagttt ccttgatttg
     3121 gctgatcatt tctgggtcag caagaaccat taagtgagca tcaaaaactt gagctgcttc
     3181 ttcaccgagc gtacctactg ctttctcgcg aataacagaa agctcgtctt gtgatgcctg
     3241 tagagcggca tcaaggcgag cttcttctgc gtttgtatct tcgactgtaa tagtctcaaa
     3301 tgacaaatcc ggctgaacga gtagatatgc ttttgcaact gcaacaccgt cagatgctgc
     3361 gattccttta agcatttctg tcatttccct tatgccaatc cttctttttc cattgtttct
     3421 gagattgcag cgatagcgtc atctgcatct gcaccttcag ctgagatagt tacgtcagca
     3481 ccttggccaa caccaagact cataacaccc ataattgatt taaggttaac tgatttacct
     3541 ttgtactcaa gagtgatatc tgaagcaaat ttgctagcag tttgtaccaa caatgttgct
     3601 ggacgtgcgt gaatacctgt ttctgccact acgtggaaat ctttagaagc catagtttga
     3661 ctctcctttt gttctttctt tttttgagtt atatgtgata acccttacaa tttagtatta
     3721 taccatcttc taggattttt ttcaagcatt ttctggattt tccttcaatt tcctttcaga
     3781 taacttgctg aaaatcttct atcctagata acaaaacaca ggatatagtt tctttaaaaa
     3841 caatttatag gataatcatt gctatttcac aatacaaaca ctatatattg tgtttatata
     3901 taaaaacaac aaaagaacac cactatattt agttcaaatc attgacaaaa ttttattttc
     3961 tgatatacta agatagtatt aaattttgaa gaggagttac acaatggtaa ccgtttattc
     4021 taaaaacaat tgtgtccaat gtaaaatgac caagcgtttc ttggacagta ataatgtctc
     4081 ttatcgtgaa atcaatcttg atgagcaacc tgagtacgtc gatcaagtta aagagctcgg
     4141 ttttagcgca gctcctgtta tccaaacacc aactgaagtc ttttcaggtt tccaaccagg
     4201 aaaactgaaa caattagcat aatcttagta catcatccag aagaaactgc ttttagggct
     4261 aacttagaag cctttctttt gtaattagat aagggaaatt ttatgggatt aaaacatctt
     4321 gaagacgtga cttacttccg tcttaataac gaaattaacc gtcctgttaa tggacaaatc
     4381 atgcttcata aagacaagga agccttggat gctttcttta aagaaaatgt agttccaaac
     4441 actatggttt ttgattcaat caaagacaaa atcaattacc tcattgaaca caactacatc
     4501 gaaacagcct ttatcaagaa ataccgtcca gagttcttgg aagaattggc tcaatttatc
     4561 aaagaccaaa acttccaatt caagtcattc atggcagctt ataaatttta caatcaatat
     4621 gccttaaaga ctaatgacgg tgaatactat cttgaaaata tggaagaccg tgtcttcttc
     4681 aacgcccttt atttcgctga tgggaatgaa gctgttgcaa tcgatattgc caatgaaatc
     4741 atccaccaac gctaccaacc tgctactcct tccttcttga atgctggacg tgctcgtcgt
     4801 ggggagttgg tatcttgttt cctaatccaa gtgacggatg atatgaactc tatcggacgt
     4861 tctatcaact cagctcttca actttcacgt attggtggtg gtgtgggaat taccctcagc
     4921 aaccttcgtg aagctggtgc acctatcaaa ggctatgaag gagctgcttc aggtgtcgtt
     4981 cctgttatga agctttttga agacagcttc tcttactcca accaattggg gcaacgtcaa
     5041 ggtgccggtg ttgtctacct caacgtcttt cacccagata tcatcgcttt cctttcaact
     5101 aagaaagaaa acgctgatga aaaagtacgt gtcaagactc tatcacttgg tgttgtagta
     5161 cctgataaat tctacgaatt ggctcgtaaa aatgaagaaa tgtacctctt cagcccttac
     5221 tctgtagaaa aagaatacgg tgtgccattc aattacatcg acattactga aaaatacgat
     5281 gaattggtcg caaatccaaa tattcgcaag acaaaaatca aggcgcggga tttggaaact
     5341 gaaatctcta aattgcaaca agagtctggc tatccttatg tagtcaacat cgatacagct
     5401 aaccgtgcaa atcctgttga tggaaagatt atcatgagta acttgtgttc tgagattctt
     5461 caagttcaag aaccaagctt gatcaacgat gctcaagaat tccttcaaat gggaacagat
     5521 gtttcatgta atctgggttc aaccaacgtg gttaacatga tgacttcacc tgattttggt
     5581 cgttctatcc gtgctatggt tcgtgccctt actttcgtta cagatagttc acatatcgta
     5641 gctgtaccaa cgattgacca tggaaatagc caagcccaca cctttggtct cggtgccatg
     5701 ggactgcaca gctaccttgc ccaacaactc attgaatatg gttcacctga gtctgttgaa
     5761 tttacaagca tctactttat gcttatgaac tactggacct tggtagagtc aaacaatatt
     5821 gcgcgtgaac gtggtattac cttccacaac tttgaaaaat cagactatgc taacggaagt
     5881 tactttgaca agtatgtaac tggtgaattt gttccaacat cagaccgtgt taaagaactc
     5941 ttcaaaaatg tttttatccc tggtgttgct gattgggctg aacttcgcga caaggttcaa
     6001 gaagatggtc tttaccacca aaatcgcctt gctgtagcgc caaatggttc tatcagctat
     6061 atcaacgacg tttctgcttc tatccacccg attacgcaac gtatcgaaga acgccaagag
     6121 aagaaaattg gtaaaatcta ctaccctgct gctggcttgt ctacagaaac cattccttac
     6181 tacacttctg cctacgatat ggatatgcgt aaagtcatcg atgtttacgc tgctgcgact
     6241 gaacacgtgg atcaaggact ttcactcacc ctcttcatgc gcagtgacat tccaaaaggc
     6301 ctttacgaat ggaagaggga aaataaacaa acgacacgtg acttgtccat ccttcgtaac
     6361 tatgccttta acaagggaat caagtctatc tactacgtcc gtacctttac agatgacggt
     6421 ggagaagtcg gcgccaacca atgtgaaagc tgtgtgattt agtttctagc atagaaacac
     6481 tatttttccc taagcagcac tgataaaatc aaatctacta tgtcataaca taatttatgt
     6541 aacattttaa aagtcgggct tccgactttt tgtgcgatac tcctatagaa ttatggtaaa
     6601 gtagaaataa ttgtgagttc gcaatactaa acacagaaag agattttaaa tggaaactta
     6661 ctacaaagcc attaactgga atgccatcga agatgtcatc gacaaatcaa cttgggaaaa
     6721 actgacggag caattttggc tcgatacacg tattccctta tcaaacgact tggatgactg
     6781 gagaaagcta tctaacaaag agaaagactt ggtcggaaaa gtttttggtg gtttaaccct
     6841 tcttgacact atgcaatctg aaactggggt tcaagccctt cgcgcagaca tccgtacacc
     6901 acatgaggaa gctgttttca ataacatcca atttatggaa tctgtccacg ctaaatctta
     6961 ctcatcaatc ttttctacct tgaatactaa ggctgagatt gaagaaattt tcgaatggac
     7021 caataccaat ccttacctac aaaagaaggc tgagattgtc aacgaaatct acctaaacgg
     7081 cagcccactt gaaaagaaag ttgccagcgt cttcctcgaa accttcctct tctactctgg
     7141 tttcttcact cccctctact atctcggtaa caacaaactt gccaacgttg cagaaatcat
     7201 taaattgatt attcgtgacg agtctgttca cggaacctac attggttaca aattccaact
     7261 tggtttcaat gaattacctg aagaagagca agaaaaactc aaagaatgga tgtacgacct
     7321 actctatact ctttatgaaa atgaagaagg ctacacagag agtctttatg acggtgttgg
     7381 ttggactgaa gaggttaaaa ccttccttcg ctacaatgcc aataaagctc tcatgaacat
     7441 gggacaagat ccactcttcc cagattcagc tgatgatgtc aacccaatcg taatgaacgg
     7501 tatttcaaca ggaacttcca accacgactt cttctctcaa gtcggaaatg gttaccttct
     7561 tggcgaagtt gaagtcatgc aagacgatga ctataactac ggtttagact aattctccac
     7621 cactctcaat catcaaaaag taaactagaa acatcaaagt tataacccaa caaaaatatc
     7681 gaaagttttg aaaacaaact tcgatatttt tgtttttgtt tcattttgtt gtttttgtat
     7741 ttgaatgatg agtttgttta tggtaagata gtagtaggaa acgaggtgat aatatgctca
     7801 aacaagaaaa attaaccaaa attttagaga tagtaaatag caaaggaacc ataacggtta
     7861 aacagattat ggacgaaata gccgtttcag atatgactgc aaggcgctat ttacaggaat
     7921 tagctgataa agatttgctg attcgtgtgc atggtggagc tgaaaaactt cgaaccaact
     7981 cccttttgac taatgagcga tcaaatattg aaaaacaagc cctccaaacg gcagaaaaac
     8041 aagaaatagc ccattttgca ggcagtctag tagaagaaag agaaactatt ttcattggac
     8101 caggaacaac attagagttt tttgcgcgtg agttgcctat tgacaatatc cgcgtcgtaa
     8161 ccaacagtct acctgttttt ctgattttaa gcgaacgaaa attaacagat ttgattttaa
     8221 taggtggaaa ttatcgcgat attacaggtg cttttgttgg cacattgacc ctacaaaatc
     8281 tctctaatct ccaattttct aaagctttcg ttagctgtaa tggtattcaa aacggagctc
     8341 tagctacttt tagcgaggaa gagggagagg ctcaacgcat cgctttaaat aattctaata
     8401 aaaaatattt actcgcagat catagtaagt tcaataagtt tgat
//
LOCUS       DAVHSY010000060         8184 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.061, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000060 DAVHSY010000000
VERSION     DAVHSY010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8184
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.061"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(560..724)
                     /locus_tag="VVR43_001883"
     CDS             complement(560..724)
                     /locus_tag="VVR43_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150195.1"
                     /translation="MDESKYLCYLEKYDALGSGRLLAKVNNTYYMFNKNQIEFLRYSN
                     KNAKKERKYM"
     gene            complement(1111..1971)
                     /locus_tag="VVR43_001884"
     CDS             complement(1111..1971)
                     /locus_tag="VVR43_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU6150196.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(2246..3232)
                     /locus_tag="VVR43_001885"
     CDS             complement(2246..3232)
                     /locus_tag="VVR43_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU6150197.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(3504..4979)
                     /locus_tag="VVR43_001886"
     CDS             complement(3504..4979)
                     /locus_tag="VVR43_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU6150198.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(5237..6160)
                     /locus_tag="VVR43_001887"
     CDS             complement(5237..6160)
                     /locus_tag="VVR43_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6150199.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(6174..7103)
                     /locus_tag="VVR43_001888"
     CDS             complement(6174..7103)
                     /locus_tag="VVR43_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6150200.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(7422..7643)
                     /locus_tag="VVR43_001889"
     CDS             complement(7422..7643)
                     /locus_tag="VVR43_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150201.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            complement(7597..7857)
                     /locus_tag="VVR43_001890"
     CDS             complement(7597..7857)
                     /locus_tag="VVR43_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150202.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
BASE COUNT         2498 a         1600 c         1509 g         2577 t
ORIGIN      
        1 taaaatatca tgaaaaatat agcagataaa taaaaaatac ttatcataga aaacaggaac
       61 atcgttgttc taaaaacttt cttttcacta taactagcac cccattctgt tccaaaagat
      121 atgactacga gataaacaat tctaatatat atgcgtccag gtactctccc tgacttcaaa
      181 taatatatca ttattaatag ctcgtgtata atagctacca cgcttcctac taaaaatgtg
      241 ataatatttc ttggaacttt tgaaatgttt agttgaatat cataacaagc ataacaaaga
      301 aataaagcta aaataggact acaatatagc attacttttg taattagtac aggattcgga
      361 aggaaaggta taaatttaga ttttttttgt ccaatataat catttaattt ttgtggaata
      421 tagaatcttg tcaatctgcg atatattgac aaaaacttca acccattatc atcaaatgaa
      481 tttttcttaa caagtattcc ttgtttgtaa aaataatcaa taaattggtc tatggtatta
      541 ctagtatagc aggaaaactt tacatatatt tcctctcttt tttagcattt ttatttgagt
      601 atcgtaagaa ttcaatctga tttttgttaa acatatagta agtattatta actttagcta
      661 ataatcgtcc tgagcctaaa gcatcatatt tttcaagata gcacaaatat tttgattcat
      721 ccatcctaaa ttatctccac atcaaattct gtgcattctc gtttgacatc agcggactcc
      781 tcctataaaa ttacgattag attgcatata tctagtgatt gtcgagttaa tgaaattatt
      841 gtatactata ttcaaaatat tgtcaacaaa aaaaatagaa aattttctga taatttgtga
      901 ttaaaaccaa taccatacct ctcccatcat tgaaaagcgc agtcattact taaaaagtca
      961 ctcgtttatg ttataatagg ctccataata tccatagggg atttacccac tacaaatatt
     1021 atagagccga ttttcattga gtagcaatcc tgtcatcctt ggcaggattt ttctatttca
     1081 aaaaagcaag tcgattgacc tgcttctgct ttacttttct tgtgctaatg ttttaaaatc
     1141 tttgtctaat atgggttgca cttctatttg attggcgtct agttggtggt aaaaagatgg
     1201 gggtaatacc tctaagaatt ttgcatagtc caagcgagct atggattcat agtcttctgg
     1261 tttagagccg tctcctgtga tttgaaccaa gtcaatctcc cactggactt ccttatccac
     1321 caattgctca atataggctg caggaacaaa cggttctctc ggtaaaactg tcttgactcc
     1381 ttgagctaga tggtaaacgc catgcacttt tccttctcca tcctgataga aggaaactct
     1441 cgcaaagtag gcatctgtct cttgaaccgc acgcacacgc gcttcaaact gagccaagcc
     1501 atctgcctct aaaaagcttt tcaagttctc acgactaaag aaaataggat taaaaattcc
     1561 ttggcaaatc gtaaaacgag ctacagggtc tgctagatag gcttgaatac ttgcttggaa
     1621 ataagcttca aaatcaaaac catctagccc ttcaatatca gtccctgtat aagcaagcaa
     1681 agcatctaaa aatgacttga taatctgcca gtctgtcttt gttagtaggt caggaagatc
     1741 gacacggtaa gccttttgac catcagcata actgacctta aagagaaatt gtgattgccc
     1801 cactatcgca cactcaatat actcgagacg attaagaggc tgacggagat agactacatc
     1861 atagctatgt gactccaaac cgtctagcaa ggccaagatc gacttggcat tcaaaatctc
     1921 ttgttctcct aaaatgctct gtttatttgg aataaaaaat gttttcgcca taactggact
     1981 cctttgaaat cgtttacata cagtatacct tatttttctg aaagatacaa aaacaaactt
     2041 tatattcttc gaaaatctct tcaaaccgcg tcagcttcgc cttgccgtag atatatgtaa
     2101 ctgacttcgt cagtcttatc tacaacctca aagcagtgct ttgagcagcc tgcggctagc
     2161 ttcctagttt gctctttgat tttcattgag tattagattt ttgagtacaa agcatagaaa
     2221 aacagcccct aaggactgtt tgatcttata cagtagctgc ctgatccaag ctttcaccga
     2281 tagcggctag gcgctcaatc acttcagctt gtgtcaattc attttttgaa acatagcggt
     2341 tacgtgggtg aacacggcac tcgtgtgagc atccacgaag gtacttgtct tcattttctt
     2401 ctgatgtcaa gatacgacgg ttacagaagg gatttccaca gttgacataa cgttcacatg
     2461 gtgttccatc aaaccagtct ttccctacga tggttgggtt gacatggttg acatcaacgg
     2521 caatacgctc gtcaaagacg tacattttcc catcccaaag ctcaccttga acttctgggt
     2581 ctttaccgta agttgcgatt cctccgtgca attggccaac atctttgtaa ccttcacgaa
     2641 ccatccagcc tgagaatttc tcacagcgaa caccacctgt acagtaaacc acgacacgct
     2701 tgtccatgaa tttttctttg ttgtcacgga cccattgtgg taactcacgg aagttgcgaa
     2761 tatctgggcg aatagcccca cggaaatgtc ctaggtcgta ctcataatcg ttacgtgtgt
     2821 caaggacaac ggtatcttta tcaagaagcg cttctttgaa ctcttttgga gacaagtaag
     2881 cacctgttgt ttcaagtggg ttgatgtcat tgtcaaagtc gttgtcttcc aaaccaaggt
     2941 ggacaatttc tttcttgtag cgaacaaaca tcttcttgaa ggcttgttca ctttcttcgt
     3001 caatcttgaa ccagagatct tccattcctg gaaggctgtg aacgtagtcc atgtattttt
     3061 gagttgtttc atagtcacct gaaactgttc cgttaattcc ctcgtcagcg actaggatac
     3121 ggcctttaag gccgattgat ttacagaaag ccaagtggtc tgcagcaaat tgctctgcat
     3181 tttcaattgg agtataaagg tagtaaagta agacacgaat atcttttgcc ataagatttg
     3241 ttctcttttc tattcttaaa ttttctaaat tttttattta tccatactag tatacctgct
     3301 tgagaaaacg aatgcaattt atttgactgg aaattgtaga ggattctcga aatttcctga
     3361 atggttaaaa taaggacaag agaaaacatg gatatctata tccttgtgcc aaaaaaacca
     3421 ctgccctccc cagaccaacc tgaggaaagc agtgattctt attttaggag ttaggaatga
     3481 atacacgaaa tcaatttagc tgattatttt ttgtttttca agaattcatc gtattgtttt
     3541 tgcatttcgt tcaatacttt ttcgtaggca ccttcagatt tcaatttttc catcaattct
     3601 ggaatagctt tatctgggtc tacagtacca gtgttgatag ctgtatcaaa ttgttgcatt
     3661 gtgttagcaa tagctgagat ttcagatttc acattgtcag tattgaagat aaatccaagc
     3721 gctggagatt ctttagcttc tgccaattct ttcttagaat tttcgatttg ttggtctgta
     3781 acgttttcgt tgatgtaaag gatccagttg ttaccagtgt tccatccacc catgtgagtg
     3841 tttcctttgt agccatcaag aacgcgaaca cggttttctt taccttcaat tttttcccag
     3901 ttcttgcctt ctggaccgta aacaagaccg ttcaagagtt ctggattcgt attcaagagg
     3961 ttcaagattt ccattgattt ttctttgttc ttagagttgt ttgagatgac aaagttagca
     4021 acttgtgttg tttggttttt cttgatgaag ttagtaattg gtttgatttg gatatctttg
     4081 ttggcaacac gtgaaagcaa gctgttaccg tagtcagctg gtcctactgt ttcttcacga
     4141 acgaaccaag tatcttgttg aaggtcaaag gaagtatcgc ttgttgcgac gtcttttgga
     4201 atgtagccag cttcatagaa tttgtgaaga gtcttcaagt gttctttgaa acgaggcact
     4261 tcgtaacggt ttacaacttt agtagtatcg ccttcaaggt cgataacgaa tggaagaccg
     4321 tttgctactg ggtagtcaaa gttatcagat gggatgaaaa ctttaccaat agcaaatggt
     4381 actacgtctg gagctttttc tttaatttgt ttcaagactg gctcaagagt ttcgtaagaa
     4441 gtaacacctg aaatatcgat accatattta gcaaggagag ttccgttgaa ggcaaagttt
     4501 tgagatgatg caacgttggc tgcaactgga acagcgtaaa tcttaccatt tacagtatta
     4561 cccttgatgt aagctgggtc aagtgctttg taaaggtctt taccttcttt tttgtacaat
     4621 tctgtcaagt cagcgtaagc acctttttga gcatttacaa tatagttatc tgcaaaggca
     4681 atatcatagt tttcaccaga tgatgtgata actgacattt tcttaccata gtcaccccag
     4741 ccaaggtatt ggatatccaa tttggcacca actttttctt caatgatttt gttggcattt
     4801 gctaacaatt catccaagtt gtctggtttg tcaccgattt ggtacatttt gataacaggt
     4861 ttgtcacctg aatcagcagc ttttttgctg ttacctgtca aatttccaca agcagcaaga
     4921 cctgcagcca aagcgactac actagcagat gcaaaagcat attttttcca gtttttcatg
     4981 ataaaaactc ctttttttat ttttaaactt ataaacaatg taatgatctt atactcaatg
     5041 aaaatcaaag agcaaactag aaaactagcc gcaggctgct caaagcactg ctttgaggtt
     5101 gtagataaga ctgacgaagt cagttacata tatctacggc aaggcgacgt tgacgcggtt
     5161 tgaatttgat tttcgaagag tattaacttc acacaaggga agttgggaac tgagaaatgt
     5221 tctttttcaa taagcactat tctttcacac caccgatagt caaacctttt acaaagtagc
     5281 gttggaagaa tggatataaa atcgcgattg gaagggttgc aaccacaacc atggccatac
     5341 gacctgtttc tttcggtaga gcaactccca gttgaccagt caagccgacc gctttggcaa
     5401 tgtagtccat attttgttgg atttgcatga gcaaatattg caatggatac aagttatcac
     5461 tcttgatgta aagaagggcg ttgaaccagt cattccagaa accaagagct gtcaaaagcg
     5521 tgatggttgc gatacctggt agtgacaatg gcaaacagat ttggaagaaa atccgggcct
     5581 cactggcacc atcgatacga gccgattcga gaatggcttc tggaatggtc ttcttgaaga
     5641 aggaacgcat caagatgata ttgaatggtg agagaagcat tggaacaatc aaggcccaaa
     5701 cagtgtcacc aagctgaagt acacgggtca ccatgatata acctggtacc aaaccagcgt
     5761 tgaacaacat actgagaagg acgaagatgg taaaaaatct gcgatactta aaggttgtcc
     5821 gtgaaatagc gtaggcatag gttgttgtga taaagacatt tgtcaatgtc ccaactacgg
     5881 ttacaaagac agagatgaag agggcttgta ggattttatc cttaaactgt gccaaaaact
     5941 caaaaccgtc taagccaaat tgggatggga agaagctata gccgtattgg aggaggcttt
     6001 tctcgtctgt cactgaaata atgataacga atacaaaagg taggatacaa gagagggcaa
     6061 tcaaacccga aatgatactg aagaagatat ctgctttctt actgaaggag tgaatgccga
     6121 cattatcaat tttttctttt ttaattttct tttttgccat attctcctcc tttctagaac
     6181 aaagctgagt ttggatcgac tcgtcttgca agcaagtttg ataggataac cagaatcaaa
     6241 ccaacaacgg attggtaaag accggctgct gcagccatac cgatatctgc tgtctgagtc
     6301 aaaccattaa aaacatatac gtccaaaacg ttggttacat tgtaaagctg accagcattg
     6361 tgtgggattt gatagaagag accgaagtct gcgcggaaga tatttccgac tgcaaggatg
     6421 gtcaatacag ttacaagcgg agtcaactga ggaatggtta cgttgcgaat acgttgccac
     6481 ttgctagctc cgtccactgt cgctgcttcg tagtaggttg gatcaattcc catgatcgtc
     6541 gcatagtaca tgacactgct atatccaaaa cctttccaaa tacctaggaa aagtaggaga
     6601 tagggccaga tgcccaggtc agcgtagaaa ttgacttctt tgagaccaag actttccaat
     6661 agatgattga acaccccttt atcaatattt aggaaggcat ctgtaaagaa actgatgata
     6721 acccaagaca agaagtaagg gaacaacata gaagtttgga aaatcttcac cattctctta
     6781 gaacggagct cgctgaggat aatggcaatc cctacagata caactaaacc tagaaagata
     6841 aagccaagat tgtagaggac agtatttcgt gtgataataa aggcgtctct tgaactaaat
     6901 aagaatctga aattatcgag tccgacccat ttactattta tgatactatc tatgaaacca
     6961 ttactggtca tgtggtagtc tttgaaggca accacgttcc caaatactgg aatgtaaaag
     7021 aatagaatca accagagtgc ccctggcaaa accatcaaga gaaagatcca gttgtctctc
     7081 aatgtttttg aaaacttttt cataatttcc tcccttttta ttttgatatc catctaaaaa
     7141 ttctttttta gacttttgat aacgattaca ttattagtat actcctattt gcaggttagg
     7201 ttaaactcct aattatagaa aaaactccac aaattatgta gcagatttaa aactttatca
     7261 ccactatcaa acaaatgtcc taaatcaatt gtttatttta tctctattag cccagtgatg
     7321 gcgtcactct gttataagca tccaacaacg gggtatactg aaaaatctcc agactaggga
     7381 actcagagat agttcctaat ctggagattt ttaatatgtt attaggcgtt tgctttcaac
     7441 ttagcaataa cctctttaag attatcaatc acctctgctt cagtatgctc agagcctttt
     7501 tcatctgcca agaacaaaac tgctttttga agttcttttt gagagttttc aaggacatcc
     7561 ttatctactg tttcaaggtt tgagtcttta agaagtttac ttaattcctt ggctaatttc
     7621 ttgagtttga tttgcagact catcttctcc tgctgtttct ttgcccgctg tttgtcctcc
     7681 atccttagtt gctgactggc tttccttaat ggactctagg gaagcaatgg catctttgac
     7741 tgtttgcaag atatcacgta aaccttgctc tgtcaaacta tcatctgcaa aagctttctt
     7801 agcctctgcc aaaaccagac gtgctgaatc tgtggtagga ttcgatacac ctgtcaatga
     7861 tctcaaaaga ttttctaagg tttgagtctg cttactaata ctagactaaa atcaaaaagc
     7921 attatataac agtgatatga aatcaactaa agaagaaatc caaaccatca aaacactttt
     7981 aaaagactct cgtacagcta aatatcataa acgccttcaa atcgttctat agtaaaatga
     8041 aacaagaaca gggtaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaag
     8101 tagaggtgta ctattctagt ttcaatccat tatatttcgt ctgatgggca aatcttataa
     8161 agagattata gaacttttat agta
//
LOCUS       DAVHSY010000061         7929 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.062, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000061 DAVHSY010000000
VERSION     DAVHSY010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7929
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.062"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..1400
                     /gene="galT"
                     /locus_tag="VVR43_001891"
     CDS             <1..1400
                     /gene="galT"
                     /locus_tag="VVR43_001891"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU6150203.1"
                     /translation="KNRVLALIGEEGTDRISDENDLKQIKDYLVEIALKNGKIKDLIE
                     EKECLGAELMNFIVPLPSRLNDIFWSSYDISPQEAVEEFYKLSKDSDYIKTSAIAKNI
                     EFRASTKYGELEITINLSKPEKDPKTIAAEKLVKATNYPKCLLCMENEGYQGRINYPA
                     RSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIFLNSQHVPMAITSKTFEQLLEIVDILP
                     GYFAGSNSDLPISGGSILSHNHYQGGKHIFPMEKAKFESEFRFKDFEDVNAGIVKWPM
                     SVIRLQSENKNRLLDLATKILNKWREYSDLEVDIIAMSEDIPHHTVTPIARKVDGRYE
                     LDIVLRDNHTTEQYPDGVFHPHQDVQHIKKENIGLIEVMGLAILPPRLKTELEEVGKY
                     LLGEDNAIAAYHLEWADQLKEKYSGINKEEVNSVVQHEAGQVFARVLEDAGVYKNTPS
                     GHEAFMRFVKSVGIN"
     gene            1413..2423
                     /gene="galE"
                     /locus_tag="VVR43_001892"
     CDS             1413..2423
                     /gene="galE"
                     /locus_tag="VVR43_001892"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU6150204.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVVIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            2590..3249
                     /locus_tag="VVR43_001893"
     CDS             2590..3249
                     /locus_tag="VVR43_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU6150205.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRVTEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVRFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3274..4341
                     /locus_tag="VVR43_001894"
     CDS             3274..4341
                     /locus_tag="VVR43_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU6150206.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIPGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSISGLQGGTGRAILASILVRYLDDKGELGVSEKGWEVAKEYLKNAYTL
                     QKGESSIVKMLDKEDPIQYGMMWGSGALVGQKEQNVVFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKNFGSIPANKDALTELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            4444..5454
                     /locus_tag="VVR43_001895"
     CDS             4444..5454
                     /locus_tag="VVR43_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6150207.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSENQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5466..7157
                     /locus_tag="VVR43_001896"
     CDS             5466..7157
                     /locus_tag="VVR43_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU6150208.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKARFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7160..7870
                     /locus_tag="VVR43_001897"
     CDS             7160..7870
                     /locus_tag="VVR43_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU6150209.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2655 a         1118 c         1567 g         2589 t
ORIGIN      
        1 tgaaaaatag agtactagcg ttaataggtg aggagggaac tgatcgcatt tccgatgaaa
       61 atgacctgaa acaaataaaa gattacttag tggaaatcgc cttaaaaaac ggtaaaatta
      121 aagatttaat cgaggaaaag gaatgtttag gggcagagtt aatgaatttc atagttcctt
      181 tacctagtcg attaaatgat attttttgga gttcatatga tatatcacct caagaagcag
      241 ttgaagagtt ttataagtta agtaaagata gtgattatat aaaaacttct gctattgcta
      301 agaatattga gtttcgagca tcaactaaat acggagagct agagattacg ataaatttgt
      361 caaaacccga aaaagatcca aaaacaattg ctgctgaaaa attagtaaaa gcaactaatt
      421 atcccaaatg tttactatgt atggaaaatg aaggatatca ggggcgaata aattatccag
      481 cacgttcgaa tcatagaatt attcggttga aacttggtga cgaagtatgg ggattccagt
      541 attctcccta ctcatacttt aatgagcatg cgatattttt gaatagtcaa catgtaccaa
      601 tggctattac ctctaaaaca tttgaacaat tattggagat tgttgatatt ttgccaggat
      661 attttgctgg ttcaaattct gatcttccta tctcaggagg ctccattctt agtcataacc
      721 actaccaggg agggaaacat attttcccaa tggaaaaagc aaaatttgag agtgaatttc
      781 gttttaaaga ctttgaggat gttaatgctg gtattgtaaa atggccaatg tcagtaatta
      841 ggttacaaag tgaaaataaa aatcgcttgt tagatttagc tactaaaatt ctaaataagt
      901 ggagagaata ttcagattta gaagtagaca tcattgctat gtctgaagat attccacacc
      961 atacggtgac tcctattgct cgtaaagtag atgggagata tgaattggat attgttctga
     1021 gagataatca tactactgaa caatacccag atggtgtttt ccatcctcat caagatgtac
     1081 aacatattaa aaaggaaaat attgggttaa tcgaagtgat gggacttgcg atattaccac
     1141 ctcgtttgaa aacagagtta gaagaagttg gaaaatatct tttaggagaa gataatgcaa
     1201 ttgcggctta tcatttagaa tgggccgacc aattgaaaga aaaatattct ggtattaaca
     1261 aagaagaggt taatagcgta gttcaacacg aagcaggaca agtgtttgcg agagttcttg
     1321 aagatgcagg tgtttataag aatactccgt ctggacatga agcgtttatg agatttgtta
     1381 aatcagttgg aattaattag gaggaaaccc aaatggcaat attggtaaca ggcggtgctg
     1441 gttatattgg tagccatacc gtagtagaat tactaaattt aggaaaggaa gtcgtcattg
     1501 ttgacaacct ttctaactct agcatcttgg tgttagaccg tattgaagca attacaggaa
     1561 tacgtcccgt gttttacgaa ttagatgttt gtgataaaca agcattgaga aaggtatttg
     1621 aacaagaatc gattgatgct gcaattcatt ttgcaggtta taaagctgtc ggagaatccg
     1681 tgcaaaagcc tgtgatgtac tacaaaaata atattatgag tacattggca cttgttgaag
     1741 tgatgtcaga atttaatgtt aaaaagattg tcttttcttc aagtgcgact gtatatggaa
     1801 ttaacaatca gtcacctcta attgagacga tgcaaacaag tgcgacaaat ccttatgggt
     1861 atacgaaagt gatgcttgag caaattttaa aagatgttca tgtggcagat tcagaatgga
     1921 gtattgcgtt gcttcgttat ttcaatccaa ttggtgctca tgagtctggt ttgattgggg
     1981 aagatccctc aggaattcct aacaacttga tgccctatat tgcgcaagta gcggtaggta
     2041 agctgtcaga gctaagtgtg ttcggaaatg attatgatac gcttgatggt actggtgtgc
     2101 gtgattatat ccatgtagta gatttagcaa taggacatat aaaagcttta gaaaaagtat
     2161 ctgaaaaaac agatgtttat atctataacc taggctcggg agaaggcact agtgtattac
     2221 aacttgtaaa tacatttgaa agtgttaata agatccctat tccttataaa atagttccaa
     2281 gacgttcagg agacgttgca acttgttatg caaatgcaga caaagcatat aaggaattaa
     2341 attggaggac aacaaaatcg attgaagaca tgtgtagaga tacatggaat tggcaatcaa
     2401 aaaatcccaa tggctataat tgatgatact gtctatatga gtgttgtatt ttgggaaaat
     2461 tacttaacct tttaatgaaa gataattttt taaaaaaatg tttgaaagcg cttgacaaag
     2521 taaacggttt cgttatataa tataagcata gatgacaccg gtgtcaaata taaaaaagag
     2581 ggtctttata tgaaaaacct aacaaaaatt aagttcaaag aaaatggaga atttaatcat
     2641 tttccaggaa atactgttgt agcaaatctt tatactaaac aagatttgat ggaagttgtt
     2701 gatattattc aatcacgtta tagagaatta ccatttatcg ataagtttac tttaactcca
     2761 aggaattcta ttcacatgac tgtaattgaa ttgttgtgcc atgaaaatcg tgaaacggag
     2821 ttttggagca gtaatcttcc tcttgataca cctttacagg aaatacatga ttactttgct
     2881 aaacaacttg aaatttttcc attgttggat gaagaaattc atatgcgtgt gactgaaatg
     2941 ggaaaacaaa acatactagt tgaacctgca gatgaagctt ctgcaaagag attagaagaa
     3001 attcgtactt atgtttcaga aaaagcaggt gttcgtttcc ctaatcatga tagataccaa
     3061 ttccatattt caattggata tcttcggatt cctctaaccg aagaggagga agaagagttt
     3121 actaaagtca gagcagaatt aactgaaatt ttattagaga agattccaac tattactgta
     3181 aaccgtattg actatactgt atttgaagat atgagacaat ttgttccata tcacgaaaaa
     3241 tttaaataaa ataataaaaa aggagaactg atcatgaaaa aaatgaaagt ttggtctact
     3301 gtacttgcaa cgggagttgc tcttactaca cttgctgctt gctctggagg ttcaaattct
     3361 acgactgctt cttcatctga agaaaaagct gataaaagtc aagaattagt aatctattcg
     3421 aactcagtct caaatggtcg tggtgattgg ttaactgcta aagcaaaaga agctggtttt
     3481 aatatcaaaa tggttgatat ccctggcgct caattagcag accgtgttat tgctgagaag
     3541 aataatgcag ttgcagatat ggtatttgga attggtgctg ttgattcaaa taaaattaga
     3601 gatcaaaaat tactagtaca gtacaagcct aaatggttag ataaaattga tcaatcttta
     3661 tcagataaag ataattatta taatcctgtg attgttcaac cattagtttt aattggggcg
     3721 cctgatgtaa aagaaatgcc taaagattgg acagaattag gtagtaagta taaaggtaaa
     3781 tattcaattt ctggtcttca aggtggtaca ggacgtgcaa ttctagcaag tatcttagtt
     3841 cgataccttg atgataaagg tgaattaggt gtttccgaaa aaggttggga agtagcaaaa
     3901 gaatatttga aaaatgcata cactcttcaa aagggagaaa gttcaattgt taagatgtta
     3961 gacaaagaag atccaataca atatggaatg atgtggggtt ctggtgcatt agttggacaa
     4021 aaagaacaaa atgttgtttt caaagttatg actcctgaga ttggtgtacc atttgtaact
     4081 gaacaaacta tggttttaag cactagtaaa aaacaagcgt tagctaaaga atttattgat
     4141 tggtttggtc aatcagaaat tcaagtagaa tatagtaaga actttggatc tattcctgca
     4201 aataaagatg ccctaacaga gttacctgaa gatacgaaaa aatttgttga tcaagtgaaa
     4261 ccacaaaata ttgactggga agctgttgga aaacatttgg atgaatgggt agaaaaagct
     4321 gaattagaat acgtacaata agaaataaga gttaattttt atgtccaagt ctctctatta
     4381 tttctaaatt tatagaagaa ataaagagag gcttttggtt tagtaataga gggagttagt
     4441 gagatgatta aatttgataa tattcaaatt aaatatggtg attttgttgc aattgataat
     4501 ctgaatttag atatacatga aggggaattt tttacatttc ttgggccttc aggatgtggt
     4561 aaatcaacta ctttgagagc attggtaggt tttctagatc catcatcagg aagtattgaa
     4621 gttaatggaa cagatgtcac tcatttggaa cctgaaaagc gtggaattgg tattgtattt
     4681 caatcttatg ctctatttcc aactatgact gtttttgata atattgcatt tggtttaaaa
     4741 gttaagaagg tagctccaga tgttattaaa gctaaagtat cagcagtagc agcaaaaatt
     4801 aagatctctg atcaacagtt acagcgtaat gtatcagaat tatctggggg tcaacaacaa
     4861 agggtagcgt tggctcgtgc tctggttctt gaacctaaaa ttctttgtct agatgaacca
     4921 ttgtcaaacc ttgacgcaaa attacgtgta gatttgagaa aagagttgaa aagacttcaa
     4981 aaagagttag gtattactac tttatatgtt actcatgatc aagaggaagc cttgactcta
     5041 tctgatagaa ttgcagtctt taacaatgga tacatcgaac aggtcggtac accagtagag
     5101 atttatcata attctcaaac tgaatttgta tgtgatttta ttggagatat taatgttttg
     5161 accgatgaaa cagtccacga agtattactg aaaaatacaa gcgttttctt agaagataaa
     5221 aaaggataca ttcgattaga gaaagttcga ttcaatcgtg aaactgaaca agattttatt
     5281 ctaaaaggga cgattattga tgttgagttt tctggagtta caattcacta tacaataaaa
     5341 gtttctgaaa atcagattct taatgtaaca agtattgata gtcaggctgc tattagatct
     5401 gtcggagaaa gtgtggaatt atttatcaca ccatcagacg ttctgcaatt ttaaggaggt
     5461 gcagtatgcg tcataaatta aatttaaaag attggcttat tcgtttaggg ttaatctggt
     5521 tcttagtaac atttattatt tatccaaact ttgatctagt agtgaatgta tttgtaaaag
     5581 gaggagaatt ttcccttgat gctgtacatc gtgttctaaa atctcagagg gcacttcaga
     5641 gtattatgaa cagttttaag ttagcatttt cactcattat tacagttaat gtcgtaggta
     5701 ttctttgtgt tctatttaca gagtactttg atattaaagg tgctaaaatt ttaaaattag
     5761 gttatatgac ctctttaatt tatggaggag tggttttagc gactggatat aaatttgtct
     5821 atggtcctta tggattgata acaaaatttt tacaaaatgt tatcccttct ttagacccta
     5881 actggtttat tgggtatggt gcagtcttat tcattatgac attttcagga actgctaatc
     5941 atacattgtt tttaacaaat acaattcgaa gcgttgacta tcacactatt gaggctgctc
     6001 gaaatatggg agcaaaacca tttactgttt tccgaaaagt agtgttacca accttaattc
     6061 caactctatt tgcacttact attatggttt ttcttagtgg tttatctgca gtagcagcac
     6121 ccatgattgt tggtggtaaa gaatttcaaa ctataaatcc aatgattatt acatttgcag
     6181 ggatggggaa ttctcgtgat ttagctgccc tacttgcaat tattttaggt attgcaacta
     6241 caattttgct tactatcatg aataagatag aaaaaggtgg aaattatatt tctatctcta
     6301 agactaaagc gcctcttaaa aaacaaaaaa ttgcgtctaa gccttggaat atcattgctc
     6361 acattgtagc atatggattg ttcacagttt tcatgcttcc actaattttt atagtattat
     6421 actcatttac agatccagtt gcaattcaaa caggtaactt aacattatca aactttactt
     6481 tagaaaatta tcgcctattc tttagtaata gtgcggcatt ctctccattc ttggtcagct
     6541 ttatttattc tattatcgct gcgacaacag caacaattct cgcagttgta tttgctcgag
     6601 ttgtcagaaa acataaagct cgttttgatt ttttatttga atatggtgct ctacttcctt
     6661 ggttactacc aagtacactt ttagcagtaa gtttattatt tacttttaat cagccacaat
     6721 ttcttgtctt gaatcagatt ttggtaggta gtttggtaat tctacttatt gcatatatag
     6781 ttgtaaaaat cccattttct tatagaatgg tacgtgctat tttatttagt gttgatgatg
     6841 agatggaaga tgcagcaaga agtatgggtg cttcaccttt ttatactatg atgaaggtta
     6901 tcattccatt tattttaccg gttgttctct ctgttattgc tttaaacttt aactctttat
     6961 taactgactt cgacttatct gtattccttt accatcccct agctcaacca ttaggtatta
     7021 cgattcgatc tgcaggtgat gaaacagcaa catctaatgc acaagctctg gtatttgttt
     7081 atacaattgt tctgatgatc atttctggaa cggtattata cttcacacaa agaccggggc
     7141 gtaaagtaag gaaataatca tgacagccac tagtcttggg ttatcaaata ttgaaatagt
     7201 tgtcaggatt gttttatcag tagtcattgg tagtataatt ggtttagaga gagggagcaa
     7261 atcccagcct gcaggcatcc gaacttatag tattgtttgt ctagctgcat gtttgattat
     7321 gatgacgaat gaatacgtat cttataaatt tgggacagga gatcctacac gattaggagc
     7381 tcaagttata tcaggtgtgg gttttctagg cgctggaacg attcttatta cagataaaaa
     7441 gaaaattaca ggtctgacaa ctgcagcagg catttgggct tcggcaggaa ttggattagc
     7501 tattggagta ggtttttatg agggagctct tttagtagcc atttctgttt ggggtgtgat
     7561 atccatgttc caaccactaa aaaaatatct gcaaaatcgt tctaaaatga ttgaattgta
     7621 tatagtggtt aaatctacag aagcctataa tcgtgtattg gtttattgtg cagaaaatgg
     7681 tatcagaatg accgattcaa gaacagcgtt tggagatgtt aattctgaca gaattgaata
     7741 ctttgatgtt ccagataaaa aaatagcgtc atttattact ctggaattat caggtagatt
     7801 tgaacatctt cgactgatgg aagaaattgc taatattgta ggtgttattt atgtcgaaga
     7861 aattagctga aatttagtaa acaaagggac agatgttttt gtccttttgt tttttagatg
     7921 ttttaatca
//
LOCUS       DAVHSY010000062         7852 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.063, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000062 DAVHSY010000000
VERSION     DAVHSY010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7852
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.063"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            31..891
                     /locus_tag="VVR43_001898"
     CDS             31..891
                     /locus_tag="VVR43_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150210.1"
                     /translation="MVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQEYCQGQPY
                     GLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQSYLGGNTV
                     WIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAIFENLLDSY
                     LIQNQSKVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYDNEALRDLS
                     KQYLNKNISELQDGSFEDGIQDAVASKQIVVINEFIACLNSRCVPSQYDRFFYKDRPY
                     IFSRKSPIKG"
     gene            1207..2184
                     /locus_tag="VVR43_001899"
     CDS             1207..2184
                     /locus_tag="VVR43_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150211.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGVAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLNKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            2561..2935
                     /locus_tag="VVR43_001900"
     CDS             2561..2935
                     /locus_tag="VVR43_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEU6150212.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            3143..4045
                     /locus_tag="VVR43_001901"
     CDS             3143..4045
                     /locus_tag="VVR43_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150213.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFVIIMLTTIFFWNIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            4101..4454
                     /locus_tag="VVR43_001902"
     CDS             4101..4454
                     /locus_tag="VVR43_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU6150214.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYCIGYGVLNRGCDIN
                     GNPYPWDGFISATVR"
     gene            4451..5179
                     /locus_tag="VVR43_001903"
     CDS             4451..5179
                     /locus_tag="VVR43_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150215.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLVINSILLISFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGKDFDTKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            6314..6553
                     /locus_tag="VVR43_001904"
     CDS             6314..6553
                     /locus_tag="VVR43_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150216.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            6572..6817
                     /locus_tag="VVR43_001905"
     CDS             6572..6817
                     /locus_tag="VVR43_001905"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150217.1"
                     /translation="MSLSAISSISKLTSCCIVAKDLSKNTMKLDVIFFEDKNKSSAVL
                     GLRRDKSGVFKPVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            7103..>7852
                     /locus_tag="VVR43_001906"
     CDS             7103..>7852
                     /locus_tag="VVR43_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150218.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTVVRAEESPVASQSKAEK
                     DYDAAVKKSEAAKKHYEEAKKKAEDAQKKYDEDQKKTEAKAEKERKASEKIAEATKEV
                     QQAYLAYLQASNESQRKEADKKIKEATQRKDEAEAAFATIRTTIVVPEPSELAETKKK
                     AEEAKAEEKVAKRKYDYATLKLALAKKEVEAKELEIEKLQYEISTLEQEVATAQHQVD
                     NLKKLLAGADPDDGTEVIEAKLKKGEAELNAK"
BASE COUNT         2694 a         1041 c         1429 g         2688 t
ORIGIN      
        1 aagtttataa gaaaaaaatc ttttaagtat ttggttctat atccatttac ttatgatggg
       61 agctggagat ttcaacctat aaacttactc tactttccag aaatggtgag agatgtcatt
      121 ccgattaatt tagttcaaga atattgccaa ggacaacctt acggactgtt aaaaaagatg
      181 ctgaaaagaa ttcgattgtc acgagagata tctttactcc tggctactat tatcgtctat
      241 ttttttacgc atagaattct acctctttca gtatttacgt tcatattttc ttacatattg
      301 ctatttgcac aatcttattt gggtggtaat accgtttgga ttggaaatag aagattaata
      361 atagatgatg aatttgaaaa aatcttgctt tcaaaaagtt atataaaaga aatatcatct
      421 gcacgatact cggaatactt gacatgtgaa tacaaaaacc ttacaccaat catattgtta
      481 gctatttttg aaaatttgct tgactcctac ttgattcaga atcagagtaa ggttgactta
      541 gatatttttt ataaagtttt acctttgctt tataaagaaa aatatactat gggattcaat
      601 tactttgtaa gtttaaatta tttactatat aaggttggat ttttgggaat catttacgat
      661 aatgaagcat taagagattt gtcaaaacaa tatttaaaca aaaatatttc ggaattacaa
      721 gatggttctt tcgaggacgg tatacaagat gctgttgcct ctaaacaaat agtagttata
      781 aatgaattta tagcttgttt aaattccaga tgcgtgccat cccaatatga tagatttttt
      841 tataaagata gaccttatat tttttccaga aagagtccta ttaaggggtg aaaatttgtt
      901 acatttggat taacaagtgt cctagggatt agaaataact ctagtatagc tagatatttt
      961 tgagtaacta gaaatatcat taggctactc atatgattgc cagaaaagat ggctgatgaa
     1021 tcttatttat actgttgcag tagggcattg tctaggataa ataagctatc ttgatggggg
     1081 agattggaat aattttagta gaaacattaa aggattatgg acaagtagcg caggattagg
     1141 tgatgcaatg tgctaagttg gcttggtgtt agcagtagta ttatttaaca atggaaagta
     1201 gactaaatga aaaataaacg ttattttttt gacacaattt taataatttt actgcttata
     1261 agcacgatat tttgtgtcag cccagtattt ataaaattgg acatcttagg aaccccctct
     1321 catgccatct taacctttgt attggcgata ccgttattct atattttgtc tcaatgctta
     1381 catactttgc tattactagt ttcctcaatc ttttgtaaat taagaccaat ttatttttat
     1441 tttatatttg tgatcattat aggagctagg aaatactatc gaattctctt tcaccaacta
     1501 atgggattta gtccaggagt agcagtgttt tataaggaga gtcaaacaac taagaatctg
     1561 tttaaatttt actacttctt gtactttaca acactaattt catactattt tttctttact
     1621 tttgtgtatg acaaaccgtt gcttttgcct cttattccat tttctattat catagcatta
     1681 gtacaaaaac tttatagaat tgagaatcaa caattatttc tgttaaaatc aaaggtacta
     1741 acaatactgg aatctaagaa ggattgtgag tttaatcttc aggattatca tgaaatttgg
     1801 aaattgcaat caaaatctga gttgccatgc gtggctttat cttatatcag tttgatcaag
     1861 ccatatcttt cagagagcgt gcgtgaacaa attgatttat tagaagttaa gcgatttaaa
     1921 aaaataaatc atccaatatc actttatggt atgttggatg ttataaaatt aaatctatat
     1981 ttacggcatt ataatgaaaa aaataaatat gaatcaatgt taaataaaat tttagaggta
     2041 agaccagact ttgttttaat cgagcagaat attgatgata gtttaaatag ctcgcaacca
     2101 ttatctttat ctttagccat ttcagaaatc caacttttgc ttgaagtgta tatggggatc
     2161 aaacatgttt caattaggag ataaaaccag aataatattt gccattatag gggcaagttg
     2221 catattagtc agtatgtatc ttatacctct cattaacacg gataataaat tttgggaaat
     2281 acttttattt ataataggtg tattgctaat tggaattgag ttactaagtc aaaaaaaata
     2341 aattttgaaa tagtattagt gagttcgcaa tcatttatta ctagtggttt agaactgtta
     2401 agtttcaaac aataattgat tttaaacctt aggtaaccta taaaaacaaa taaggtagag
     2461 aaaggatatc ttatctaggt agctaagtga taaaaacaca gtcgtctatc acttgttagg
     2521 aaactatcct aactatgctt aataaaaaag gagaaaataa atggaactcg tattaccaaa
     2581 taattatgtt gttcttgagc aagaagagat gatgtatctt gatgggggat tttctattcc
     2641 gagatggcct gttgcaacag ccattaatat agcttttaat ggtgttttag gtggaggagc
     2701 aatcagtcta gttagaaatt atattcgtaa ttatggtttg cggcgagtta caagcgcaat
     2761 tgctggagca gctgcaagat atgttggggt acgagttgca aatagagtgg caggatttgc
     2821 actgtctgct attaatggat ttgcagcttg gatgtcaatt ggcgatgcta ttacaacaat
     2881 ctgggccaac aatgatgtaa ataggagaga cccaaattta aacgccttgt ggtaactaga
     2941 tatgggtatt aaaatggaaa aaatttttgt tattattttt tttgtatgtt tatttatatc
     3001 atccataact tttttagcct atgattttgt tagcgaagaa ataaaaaagt tgattatttg
     3061 gatgaatgtc gtttttttga ttttaatcat agcaatgata atttatccaa aattaagaaa
     3121 atgataagga cactgtaaaa ttatgatacg taaactaatc atttttttat taatgctccc
     3181 tctttttgtc ttgtggctag agttgcatgt cctagtgaat aacttactat tgaatctaga
     3241 atctcccctt gattttgtga ttagtatgag tcttgctttc tgtagtttga ttttatcaaa
     3301 aatagtttta gacatactat acgcattgaa agatttgtac aagaaagaag ctcttattac
     3361 gatttttcct tttattttta taggcaggaa gaaagtaaat gtgaggttct cgccctattt
     3421 ttcattccat cgtaaaagtt tgtcgcctga tgatttaaga tctaggatta tatggagttt
     3481 tattcttgaa attgctatta tcctagtatt tattttaaaa attccttttg tcatcattat
     3541 gcttactaca atattttttt ggaatataat ggatatcaat catctcgttt ttaataagac
     3601 ggaatttctt ttcaatcaaa ataaatggga aaaagaagat tcgtttgaaa gcgatttgac
     3661 gaaaacgtta aaggataaaa tacaaaaatc agagctaagt tattctgact taatgtctct
     3721 tcagctgtat gatgcgatga atcaatctac ctttttaacg gatagtgaac tctttgagga
     3781 tattctgagt aaaattgaag attctcataa cacccttctg tgtacaggtc ttgtcgagtt
     3841 actgctgtat gagatttcta ttagtaacaa taacaactgg caagaaaagg ttgataaaat
     3901 taggatacac ctcatcagaa tcaatcaatt agattttttc tattatacaa gttggttaag
     3961 gcaaaatttt gatttctgta tgaatagaga gtatcataaa atgaaatctc ggaaattatt
     4021 actgagtaat aaaaagatag tttaagttcg tcctatttgt aaaacaaatg aaacaatttc
     4081 aactaaggag gagaaaacaa atggaacttg tattaccaaa taattatgtt gtgattgatg
     4141 aagaagaaat gatgtatctt gatgggggag cttatttaag caagcgtgct tgtcaaggaa
     4201 tttgcgcagc tttagctatg agttcaggaa cttttatagc attagctgga gctgcagttt
     4261 taaccaaaaa actaataaac tatattaagg ttggaggtct tggaggctgg cttattggtg
     4321 cagcagcagg tgtattggct acagcagcag ggaaaatagc ttactgtatt ggatatggtg
     4381 ttcttaatag aggttgtgat attaacggga acccttatcc ttgggatgga ttcatatctg
     4441 caacagtaag atgagtaatg tagataagat tcgaaaaata cacatcatcg tgtgttgggt
     4501 gtatatattt ttatcattca gggcgattat aaatgatacg gagtattttt tgcttatttt
     4561 tttagctttt atctactcaa tagtatcact acctctatat tctgtgaaaa ataaaatagt
     4621 atctatctgt ctagttataa attcgattct gttaatcagt ttccccattt taatcaataa
     4681 atttttccca gaaagttttt tgacttatac cgtattaata agtgttttta tcctagagtt
     4741 agcaatcttt catttaattg ggaaagattt tgatactaaa ttgactaacg aatataagaa
     4801 aattagtcag ttcagaagca aggtgtctca atctccttgg ataaaatatt tagagatttc
     4861 tagttttata ttaactatat ttccatccat tctttatggt acagttgata atcatgtact
     4921 gactcttatc tttttgataa aaatttgtgt agataccacg ataaaatttt tattcatcag
     4981 attatttgac acaagtactt taatgaagag gagaatattt tttcttttcg cattggatgt
     5041 tatagcttac ttatttttag gatatctttt agtgattcaa aaagcaggct atttgttttc
     5101 ggttttactt cttttttcta atttttcagt tccatttatc aaagcaaagg aatacgaatt
     5161 atttaaaaat agcaagtaat agaaacatag gttaaatctt agaacggctt aaaatcagat
     5221 atgataaagg gaaatagtct tatctaggta actaagtgct acaaacacag tcgaggatca
     5281 cttgttagga ttacatttta atcatgctta ataagaatgg agaattccta tggggattgt
     5341 attactctga actttcgaat accttagttc tcgtgatttt gagctattct aggtttagaa
     5401 tccttcagaa tgtaaaattt taagcagtca aagacttaga atagcctgaa aacatttatt
     5461 ttatagcaat tctaaactta gaattgctca tatatatgta tttgagctgc tcgatagtta
     5521 ggacagctct attctgagaa atctgagcta tcaatgcttc agaatagtat ttcgccaatg
     5581 gtttttattg aagaggtgat tgttttatga tagtctaaaa taaaactgat ttaatggagt
     5641 aaatggagaa tcgttacatg aaacattttt ttgcaggaat tggtgagata aaacttgttg
     5701 gctacttatt gtatatatgt gtaggactag cccctctttt tcatatatat gtcataggtt
     5761 cggaactgag ttttgtgaaa atagtgttat ctattttggg agttatattt gtaagtatgt
     5821 taactattgc tcgaatttat cggacttttc tataaagaat agtttggact tgaactgtat
     5881 ctaaaaacag gggttggtcg attatcagcc tctttcttgt cgttgaaaag agtgagatat
     5941 attgactttt gaaaaaaaga tgtcataatt gagttgggat aaacctaaaa gtaatatagt
     6001 agattgaatc tggaatagtc cgttatgact gttaaaatat ttctagaaat taatttgact
     6061 ttcctaatcg atttgttcac atcttgtttc aatctactat actttctcgt taaaccgttc
     6121 ggcaattcat ggtgacatgg acacatagta gtaagcacac tatgtggctt ggcagagcta
     6181 aaaactgttc ccttgcgata agcctaataa gcacaacata gggagttaga gaagccgact
     6241 ctaatcaacc actttgggca gtagtgagaa ctgccccgtg cttttttatt ttgagaaaat
     6301 atggagtttg tcgttgaaat tacttgattg tattttggat tatcaagaaa gattcaatgg
     6361 aaaaacatgt caagtatcaa cgaattataa gtatttagag attttcaaag tgaatttttg
     6421 cttgactgat ttacatcatt tatttggctt acacaaaatc acacgagatt atgctagtca
     6481 aacaaaacct gctattcaag ctggtgtttt tattttagaa gattttagaa atatcctatg
     6541 tacaatgatg taatcgaaag gatatcttta tgtgagttta tcggcgatat cttctatatc
     6601 taagctaaca agttgttgca tcgtagctaa ggatttatct aaaaatacta tgaaattgga
     6661 cgtcatattt tttgaggata aaaataaaag ttccgcagtt ttaggtttac gaagagacaa
     6721 aagcggagta tttaaaccag ttactctaca ttttacaagc gctaagaaat atgctaaagt
     6781 tcgtaaaaca gatgtgaaag aaatgaaatg gctataaaga ttgtccgcag gcttaagctt
     6841 gcgttttttg ttgtttaacg aaattaaaaa ataagctctc tcatcggaaa tgtttttata
     6901 ggaatgaagg aagatgatgc tatgtttaaa aagagaatcg aaaggggcaa aagtagtgtc
     6961 tttatctttt tggagtagaa gcttatgata tagaaatttg taataaaaat gtaatataaa
     7021 acatttgaca aatatttacg gggggggtat acttaatata agtataatct aaaaatgatt
     7081 atcagaaaag aggtaaattt agatgaataa gaaaaaaatg attttaacaa gtctagccag
     7141 cgtcgctatc ttaggggctg gttttgttac gtctcagcct actgttgtaa gagcagaaga
     7201 atctcccgta gccagtcagt ctaaagctga gaaagactat gatgcagcag tgaaaaaatc
     7261 tgaagctgct aagaaacatt acgaagaagc taaaaagaaa gcagaagacg ctcagaaaaa
     7321 atatgatgag gatcagaaga aaactgaggc aaaagcggaa aaagaaagaa aagcttctga
     7381 aaagatagct gaggcaacaa aagaagttca acaagcgtac ctagcttatc tacaagctag
     7441 caacgaaagt cagagaaaag aggcagataa gaagataaaa gaagctacgc aacgcaaaga
     7501 tgaggcggaa gctgcatttg ctactattcg aacaacaatt gtagttcctg aaccaagtga
     7561 gttagctgag actaagaaaa aagcagaaga agctaaagca gaagaaaaag tagctaagag
     7621 aaaatatgat tatgcaactc taaagctagc actagcgaag aaagaagtag aggctaagga
     7681 acttgaaatt gaaaaacttc aatatgaaat ttctactttg gaacaagaag ttgctactgc
     7741 tcaacatcaa gtagataatt tgaaaaaact tcttgctggt gcggatcctg atgatggcac
     7801 agaagttata gaagctaaat taaaaaaagg agaagctgag ctaaacgcta aa
//
LOCUS       DAVHSY010000063         7598 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.064, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000063 DAVHSY010000000
VERSION     DAVHSY010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7598
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.064"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..648
                     /locus_tag="VVR43_001907"
     CDS             <1..648
                     /locus_tag="VVR43_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU6150219.1"
                     /translation="MPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYT
                     LEDLLATVKYYVEHPNERPHSDNGFGNASDHVRKNKADQDSKPDEDKGHDEVSEPTHP
                     ESDEKENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEA
                     LLEKVTDPSIRQNAMETLTGLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
     gene            858..3977
                     /gene="phtE"
                     /locus_tag="VVR43_001908"
     CDS             858..3977
                     /gene="phtE"
                     /locus_tag="VVR43_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU6150220.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            4203..5214
                     /locus_tag="VVR43_001909"
                     /pseudo
     CDS             4203..5214
                     /locus_tag="VVR43_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(5485..5706)
                     /locus_tag="VVR43_001910"
     CDS             complement(5485..5706)
                     /locus_tag="VVR43_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150221.1"
                     /translation="MDLFQELIYLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            5671..6300
                     /locus_tag="VVR43_001911"
     CDS             5671..6300
                     /locus_tag="VVR43_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150222.1"
                     /translation="MSKVNQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIEIASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            complement(6336..7559)
                     /gene="pepT"
                     /locus_tag="VVR43_001912"
     CDS             complement(6336..7559)
                     /gene="pepT"
                     /locus_tag="VVR43_001912"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU6150223.1"
                     /translation="MTYPNLLDHFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQMLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKEQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
BASE COUNT         2700 a         1333 c         1467 g         2098 t
ORIGIN      
        1 atgccttaca atcttcaata tactgtagaa gtcaaaaacg gtagtttaat catacctcat
       61 tatgaccatt accataacat caaatttgag tggtttgacg aaggccttta tgaggcacct
      121 aaggggtata ctcttgagga tcttttggcg actgtcaagt actatgtcga acatccaaac
      181 gaacgtccgc attcagataa tggttttggt aacgctagcg accatgttcg taaaaataag
      241 gcagaccaag acagtaaacc tgatgaagat aagggacatg atgaagtaag tgagccaact
      301 caccctgaat ctgatgaaaa agagaatcac gctggtttaa atccttcagc agataatctt
      361 tataaaccaa gcactgatac ggaagagaca gaggaagaag ctgaagatac tacagatgag
      421 gctgaaattc ctcaagtaga gcattctgtt attaacgcta agatagcaga tgcggaggcc
      481 ttgctagaaa aagtaacaga tcctagtatt agacaaaatg ctatggagac attgactggt
      541 ctaaaaagta gtcttcttct cggaacgaaa gataataaca ctatttcagc agaagtagat
      601 agtctcttgg ctttgttaaa aaaaagtcaa ccggctccta tacagtagta aaatgaatgg
      661 agcatatttt atggagaagt aacctttcgt gttacttctc ttttttagaa aaacgtaaca
      721 gaaacttgac aaaagtaatt ttaaatagta aactatttac tggttaatta aatggttaaa
      781 taaccggttt agaaaactat ttaataaagt aaaagaagtt gagaaaaaac ttcatcattt
      841 attgaaatga gggatttatg aaatttagta aaaaatatat agcagctgga tcagctgtta
      901 tcgtatcctt gagtctatgt gcctatgcac taaaccagca tcgttcgcag gaaaataagg
      961 acaataatcg tgtctcttat gtggatggca gccagtcaag tcagaaaagt gaaaacttga
     1021 caccagacca ggttagccag aaagaaggaa ttcaggctga gcaaattgta atcaaaatta
     1081 cagatcaggg ctatgtaacg tcacacggtg accactatca ttactataat gggaaagttc
     1141 cttatgatgc cctctttagt gaagaactct tgatgaagga tccaaactat caacttaaag
     1201 acgctgatat tgtcaatgaa gtcaagggtg gttatatcat caaggtcgat ggaaaatatt
     1261 atgtctacct gaaagatgca gctcatgctg ataatgttcg aactaaagat gaaatcaatc
     1321 gtcaaaaaca agaacatgtc aaagataatg agaaggttaa ctctaatgtt gctgtagcaa
     1381 ggtctcaggg acgatatacg acaaatgatg gttatgtctt taatccagct gatattatcg
     1441 aagatacggg taatgcttat atcgttcctc atggaggtca ctatcactac attcccaaaa
     1501 gcgatttatc tgctagtgaa ttagcagcag ctaaagcaca tctggctgga aaaaatatgc
     1561 aaccgagtca gttaagctat tcttcaacag ctagtgacaa taacacgcaa tctgtagcaa
     1621 aaggatcaac tagcaagcca gcaaataaat ctgaaaatct ccagagtctt ttgaaggaac
     1681 tctatgattc acctagcgcc caacgttaca gtgaatcaga tggcctggtc tttgaccctg
     1741 ctaagattat cagtcgtaca ccaaatggag ttgcgattcc gcatggcgac cattaccact
     1801 ttattcctta cagcaagctt tctgccttag aagaaaagat tgccagaatg gtgcctatca
     1861 gtggaactgg ttctacagtt tctacaaatg caaaacctaa tgaagtagtg tctagtctag
     1921 gcagtctttc aagcaatcct tcttctttaa cgacaagtaa ggagctctct tcagcatctg
     1981 atggttatat ttttaatcca aaagatatcg ttgaagaaac ggctacagct tatattgtaa
     2041 gacatggtga tcatttccat tacattccaa aatcaaatca aattgggcaa ccgactcttc
     2101 caaacaatag tctagcaaca ccttctccat ctcttccaat caatccagga acttcacatg
     2161 agaaacatga agaagatgga tacggatttg atgctaatcg tattatcgct gaagatgaat
     2221 caggttttgt catgagtcac ggagaccaca atcattattt cttcaagaag gacttgacag
     2281 aagagcaaat taaggctgcg caaaaacatt tagaggaagt taaaactagt cataatggat
     2341 tagattcttt gtcatctcat gaacaggatt atccaagtaa tgccaaagaa atgaaagatt
     2401 tagataaaaa aatcgaagaa aaaattgctg gcattatgaa acaatatggt gtcaaacgtg
     2461 aaagtattgt cgtgaataaa gaaaaaaatg cgattattta tccgcatgga gatcaccatc
     2521 atgcagatcc gattgatgaa cataaaccgg ttggaattgg tcattctcac agtaactatg
     2581 aactgtttaa acccgaagaa ggagttgcta aaaaagaagg gaataaagtt tatactggag
     2641 aagaattaac gaatgttgtt aatttgttaa aaaatagtac gtttaataat caaaacttta
     2701 ctctagccaa tggtcaaaaa cgcgtttctt ttagttttcc gcctgaattg gagaaaaaat
     2761 taggtatcaa tatgctagta aaattaataa caccagatgg aaaagtattg gagaaagtat
     2821 ctggtaaagt atttggagaa ggagtaggga atattgcaaa ctttgaatta gatcaacctt
     2881 atttaccagg acaaacattt aagtatacta tcgcttcaaa agattatcca gaagtaagtt
     2941 atgatggtac atttacagtt ccaacctctt tagcttacaa aatggccagt caaacgattt
     3001 tctatccttt ccatgcaggg gatacttatt taagagtgaa ccctcaattt gcagtgccta
     3061 aaggaactga tgctttagtc agagtgtttg atgaatttca tggaaatgct tatttagaaa
     3121 ataactataa agttggtgaa atcaaattac cgattccgaa attaaaccaa ggaacaacca
     3181 gaacggccgg aaataaaatt cctgtaacct tcatggcaaa tgcttatttg gacaatcaat
     3241 cgacttatat tgtggaagta cctatcttgg aaaaagaaaa tcaaactgat aaaccaagta
     3301 ttctaccaca atttaaaagg aataaagcac aagaaaactc aaaacttgat gaaaaggtag
     3361 aagaaccaaa gactagtgag aaggtagaaa aagaaaaact ttctgaaact gggaatagta
     3421 ctagtaattc aacgttagaa gaagttccta cagtggatcc tgtacaagaa aaagtagcaa
     3481 aatttgctga aagttatggg atgaagctag aaaatgtctt gtttaatatg gacggaacaa
     3541 ttgaattata tttaccatcg ggagaagtca ttaaaaagaa tatggcagat tttacaggag
     3601 aagcacctca aggaaatggt gaaaataaac catctgaaaa tggaaaagta tctactggaa
     3661 cagttgagaa ccaaccaaca gaaaataaac cagcagattc tttaccagag gcaccaaacg
     3721 aaaaacctgt aaaaccagaa aactcaacgg ataatggaat gttgaatcca gaagggaatg
     3781 tggggagtga ccctatgtta gatccagcat tagaggaagc tccagcagta gatcctgtac
     3841 aagaaaaatt agaaaaattt acagctagtt acggattagg cttagatagt gttatattca
     3901 atatggatgg aacgattgaa ttaagattgc caagtggaga agtgataaaa aagaatttat
     3961 ctgatctcat agcgtaagga atagcagtag aaaaagtctg aatcaaaaat gaagttctct
     4021 caaaagttag aaataaaact ctgactttgg gagaatttca ttttattatt aatatataaa
     4081 atttcttgac atacaactta aaaagaggtg gaatatttac tagttaatta attggttaat
     4141 taatttattt aatcatttaa taatgaagac atcatataaa taattataga aatgaggtaa
     4201 ttatgaaatt taaaaagaaa tatatagcag ctggatctgt tgttatcctt tccttaagtc
     4261 tgtgtgttta tgctctgaac caacatagct aacaggccaa tacagataaa aatcgtgttt
     4321 catatgtaaa cagtaataaa gacactaaga agactgaaaa tttgactcca gactaggtta
     4381 gtcaaaaaga aggaattcaa gcaaaacaaa ttgttattaa gattacagat caaggttatg
     4441 taacttctca tggcgatcat tatcactact ataatggtaa agttcctttt gatgcgctct
     4501 ttagtgaaga gctattaatg aaagccccca actatcagcc gaaagatcaa gatatcgtca
     4561 gttaggttaa gggaggatat attattaagg tagatggaaa gtattatgtt taccttaaag
     4621 atcaagctca tgcagaaaat gtacgaacaa aagatgaaat caatcgccaa aaacaagaac
     4681 atggtaaaga cgataaagga gctagtgcag aagtatctgt agcaaaatta cagggacgtt
     4741 atactaccga tgatggttat atatagtgag ttgaatttag aatagcacat catagtttct
     4801 aaatcattgt tagaaattac tttaaaatcc ccttatcaat ttgctcatat tctatttcaa
     4861 tctactatag taccacatgg tggtcactat catttcattc ctgagagtga cttgtcggca
     4921 ggtgaattag cagccacata tgtctttaac cctaatgata ttgtcagaga tacaggtgat
     4981 gcttatatag taagacatgg ggatcactat cactatattc ctaagtcatc tcttaacaat
     5041 cccccatcac actctaacac ggaagaggta ggaagttctt ctagttctgt attaagtaat
     5101 ccgtcactac atgtccatca tgaggaagaa gatggtcatg gttttgatgc caatcgaatt
     5161 ataagtgaag attcagaagg ttttgtgatt cctcatggcg accacaatca ctacatcaag
     5221 gttcaaacta agggatatga agcggctttg aaaaacaaga ttccatccct gcaatccaac
     5281 tatcaacctg gaacttttga tgagaaggca gtcttggcaa aagtagatca acttctagct
     5341 gatagcagaa gcatctacaa agacagattg agttagcttt aggtcagttt actgaaagtt
     5401 tgaaaaaaat aaaagttagt tgattgatta cttctctaaa ttttgggcac actaaaaaga
     5461 ggtcttgaca cctaaacttt aaaattaaag catattgaat ccgtgctgct gtgcgaagcg
     5521 aatagcgtct tggacgaaca ttgtcttatc tggatttctt atttctgtaa ggccttgtaa
     5581 tcttggatta taactctcct gttttaggag tacatggtag atggcaacca ataatctgcg
     5641 acagatagca aggaagaagt agaaagtctt ttgagcaagg taaatcaact cttggaacaa
     5701 atccatgaag aaggaatcag acaatccttg gcagaagaag tagaaaatct aaaagctgcc
     5761 acaaacaagg ctgatgcaga cttggatgaa gtaaacagtc aggtaaaaga tgtcttgact
     5821 cgtatcgcta gcgcccttca acaagaaaag gaaaatgctg agcaagattc tcagacactt
     5881 gtactctatc aaaaactcta cgatattctc atgtcgcttc actcttattt agaaagtaat
     5941 aatggatctg atgcggactt tgataaggtg gatgcattat tagatcaact ttctgctaag
     6001 agtaaagaca aaacagcttt acttgaatcg acaaaagcta ttctagtttt gaatcatcaa
     6061 atccagtcaa aagctagcgc aagtgaagaa acaagtccag caagaaatgc tgaagcaaat
     6121 agtgataaca ccagtgctga gaaccaacca aacgcaactg cagaatctaa cattgaaatt
     6181 gctagcgacg aaaacaaacc aagcaataca agagattcta aacctgctga atcaacttca
     6241 gaaaatgaaa caacagaatc ttctacaact actggaaatc aagaaaaacc agtagaataa
     6301 aaagaaaggc gaagtagctg agctacctcg tctttttagc ctttataagc tacgatgcca
     6361 atgatggtat caactgcacg ttccatagtc tgaaggctaa cgtattcaaa acgtccgtgc
     6421 atattttcgc cacctgcaaa gatattcgga gttgggattc ccataaagga aatcttagag
     6481 ccgtctgttc caccccggat tggttcgata ataggcgtga tacctagatc ttccataacg
     6541 gctttagcaa tggtaattgg agtcatatct ttttcaatga cttctttcat attgtagtac
     6601 tggtctgtca agttgagagt gacacggtag ctcccaagtt ctgcattcat cttatcagcg
     6661 atagattgca tggatgcttt acgcgcttca aaggcatctt tttcaaaatc acgaatgatg
     6721 tagcttgcac gcacctcctc aacactacct gtcacatcca ttagatggta aaaaccttgg
     6781 taaccttcag ttaactcagg tcggtcattt tctggaagtt gattatgaaa atcaattgct
     6841 agctgaaggg cattgaccat ctgctctttg gcagtaccag ggtggacatt acggccttgg
     6901 aaatgcaatt cagcaccagc ggctgagaaa gtctcgtact gaagttcacc tagtggacca
     6961 ccatcaacag tgtaggcaaa atccacatca aaatcttctg catcaaattt attggcacca
     7021 acaccgattt cttcatctgg accaaaacca acacgaatct cacagtgctt aatttcagga
     7081 tgagcagtta gatattcaat ggctgtcata atttcagcaa ttcctgactt gtcatcagca
     7141 cctagcaagc ttgttccatc tgttgtgatg agcatttgtc ctggatattt ttcaagactc
     7201 ttgaagtcag ctggatcgag tttgaaacca gaattcccta gttcaatcac accaccatcg
     7261 tagttttcaa ttacctgtgg attgactcct tcagcattaa aatcagcagt atccatgtgc
     7321 gatataaaac caatcttacg tgttaaagac ggatcgttgg ctggcaaggt tccaatagca
     7381 aaaccattcg gtagatagta aacattttgc agtccaacac gtttcatttc aggaattagg
     7441 acatttgttg cgaagtcaac ctgactctgt gtacttggag tagtagtaga gtgttcatca
     7501 gagcgcgtgt tgaccttaac gtaggttaag aagtggtcca agagatttgg ataagtcata
     7561 aaaaaactcc ttttttatca taaaatagaa tacaaaac
//
LOCUS       DAVHSY010000064         7266 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.065, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000064 DAVHSY010000000
VERSION     DAVHSY010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7266
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.065"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            31..342
                     /locus_tag="VVR43_001913"
     CDS             31..342
                     /locus_tag="VVR43_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150224.1"
                     /translation="MLSGLIFFLAQGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGV
                     LTIDFLFFVLLAFISSQRFSSLMSIITACHSTFYYMTADYLRENYPDFYDKHISLWEC
                     L"
     gene            361..546
                     /locus_tag="VVR43_001914"
     CDS             361..546
                     /locus_tag="VVR43_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150225.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(813..1256)
                     /locus_tag="VVR43_001915"
     CDS             complement(813..1256)
                     /locus_tag="VVR43_001915"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU6150226.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(1286..3508)
                     /locus_tag="VVR43_001916"
     CDS             complement(1286..3508)
                     /locus_tag="VVR43_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU6150227.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            4504..5133
                     /locus_tag="VVR43_001917"
     CDS             4504..5133
                     /locus_tag="VVR43_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU6150228.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(5256..7148)
                     /gene="pepO"
                     /locus_tag="VVR43_001918"
     CDS             complement(5256..7148)
                     /gene="pepO"
                     /locus_tag="VVR43_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU6150229.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVVAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         1961 a         1714 c         1392 g         2199 t
ORIGIN      
        1 attagactcg agacatcttt tgagtggctc ttgctctctg gtttaatttt cttccttgct
       61 caaggactcc tgctatttct cttgatcgtc cgactcaaac atcaattcgc tgagatttat
      121 cctcaaatca ataaaaagat tcgcttctac tatttagggg ttctcaccat tgattttcta
      181 ttttttgttc tcttagcctt cattagttct cagcgttttt catctcttat gtcaattatc
      241 actgcttgcc attctacttt ttattatatg acagctgact acctaagaga aaactatcca
      301 gacttttacg acaaacacat ctctttatgg gagtgtctct aaggaaaagg aggttttagc
      361 atgaaaaaaa tcatcttcat caaaaccatt caactccttg tcattgatgg aatcatgctg
      421 gcatttttga catttaaaag ggggcttact tgggactgga ttttgattta tagcggttgg
      481 ctcattttct ttcatcctgt gctattgacc tatctttcaa accaactttg tgaccacttt
      541 agttaactct attcccagat tagaccgaga ttctggcgtt ttgctttaca aattctccta
      601 tgggatagcc tgatgattct ctccttggtg tctttaagtg atattccact tttccttcag
      661 ggaactctcc tcatcctagg acacctcatc ccttcctatc gcatctgcca aagcctgaaa
      721 agagacttcc cccaagcata tcaagaaccg atttcttttt ggagtatttt atgatagatg
      781 agaaagacca agccgactgg gcttggtctt tcttatctct ttttagtatc taggataatg
      841 gtaacaggtc cgttattaac cagctcaacc tgcatatctg ctccaaagat acctgtctga
      901 acgggcactt cttgcgctaa tttttgattg aaagcatcat agaagtctga tgccatatca
      961 ggtttagctg cccctgtaaa ggctggacga ttgcctttct tagtatccgc aaagagggta
     1021 aactgagaaa tagagaggat ttctccttca atatctttga cagacaggtt catcttgcct
     1081 tctgcgtctg aaaaaatccg catattgacc agttttctca cagcatagtc caaatcttcc
     1141 tcttggtcct ctggtccaac accaaccagc aataaaagtc cctgattgat ttttccctga
     1201 atctggcctt ctatactcac ttgggctttt ttaacccgtt ggataatgat tttcataata
     1261 gcctttctag taagagctag gacaactagc cgttggtccg tttgacagag taaacttctg
     1321 gcacactctt aattttatcg acaaccgtgg tcagtgtaga gaggttggca ataccgaagg
     1381 acacatggat attagcaaac ttcatatcct tggttggttg ggcattgacc gttgaaatat
     1441 tcttggttgt atttgaaaga acttgcagta catcgttcaa cagtcctgta cggttgagac
     1501 cgtagatatc gatatgggcc atatactcct tatttgagct agagtactgg tcttcccatt
     1561 ccacatcaag gagacgttgc tcgtagtttt cttgggcacg cagattcata cagtccacac
     1621 ggtgaatagc cacaccacga cccttggtaa tgtagccaac aatatcgtca ccaggcacgg
     1681 ggttacaaca cttagcaatc cgcactagga gaccagaagc accttcaata accactcccc
     1741 cctcatgctt gaccttgaga gtttctttat tttcaacctt gacctcgcca cctttgacaa
     1801 gctcctctgc ctcagccttg gccttggcac gctcttcctc acggcgttcc ttttcagtca
     1861 gacggttaaa gacggtaatc gcaccgattt ccccaaaacc aatggccgca aagagggagt
     1921 cttctgtctt gtaactggtc ttttgcagaa cttgatccat gtggcgcttg tccataaatt
     1981 tatttgccac atagccattt tcttggaact gagccatcag catctcacga cccttgttga
     2041 cagacaattc cttatcttgg tttttaaaga actggcgaat cttattgcgc gccttgctag
     2101 tcttgaccat attgagccag tcacggctag gtccaaagga gttcgggttg gcgataattt
     2161 caacctgatc ccctgtcttt aacttggttg tcagtggaac catgcggcca ttgaccttgg
     2221 caccagttgc tttttcaccg accttggtat ggatttcgta ggcaaaatca atcggtcctg
     2281 aatctttggg aagggaacgg acagctccat ctggggtaaa aacgtaaatc tcctcagcca
     2341 gatagttttc cttaacagag tccacaaatt ccttagcatc atcagcctgg tcttggagct
     2401 ccatcatctc cttgatccag ttcattccaa tagctgattc cttgctgtta acttgcccct
     2461 ttataccttt cttataagcc cagtgagccg caaccccgta ctcagccacc tcgtgcattt
     2521 ccttggttcg aatctggaat tcaatcggcc cttttggccc ataaacagtc gtatggatag
     2581 actgataacc attggccttg cggttggcaa tatagtcttt gaagcgacct ggcatcggtt
     2641 tccaaaattc atgcacgtaa ccaagcatgg cataaacatc actttgggta tctaaaatac
     2701 aacgaatagc aatcagatca tagatttcct caaaccgttt tctcttgtcc tgcattttgc
     2761 ggaaaattga gtaaatatgc ttgggacgac cataaatctt ccctttcaag tgacgttctg
     2821 tcgtatactc ctctaatttt gtgactacct catccaccaa ggcctcacgc tccctgcgct
     2881 tttccttcat catatgggta atcttgtaaa actccgttgg attgagataa cggaaagaca
     2941 agtcttctaa ttcccatttg acactggaaa tccccaaacg atgggcaagt ggggcataga
     3001 tttccatggt ttctttggaa atacgctcct gcttgtcttt tcgaagatgt ttcagggtcc
     3061 gcatattgtg caagcggtca gacagtttga ccaaaataac gcggatgtcc tcagacatgg
     3121 ccatgagcat cttgcgatga ttttccgcta attgctcctc gattgatttg tactcgacct
     3181 tgccaagctt ggtaactccg tcaacaatca cccgcacatc aggaccaaac tctctttcca
     3241 aatcgtccaa ggtcgcatct gtatcttcca ccacatcatg caagaatcca caagctactg
     3301 ttacagcatc cagctttagc ttagctaaaa tacctgccac ttggataggg tgaatgatat
     3361 aaggctcgcc tgatttgcga tattgaccac tgtggcattc aacagcatag accaaggcct
     3421 tatggacaaa atgaacatcc tcttccgtta aatattcttt ggttaaagcg acaacttctt
     3481 cgcctgttaa attcacttct ttcggcatct ctactctcca attcttccta ccattttatc
     3541 acttttttaa gaatatgaaa actagattgg aacagaataa gaaaaaaata attcaaaatt
     3601 gcttgataat tctgaattat cggcccataa tatactacga agttagattt taaacttagg
     3661 tgatagaagg agagatagaa gaacggaaac catattgtaa cccaaagact ttctgatttc
     3721 cccaattcca ttgaagatac gaaagataaa cggtggaact cgtatcacat acactggtac
     3781 cttgactgga ttttggaatt aatactcaat gaaaatcaaa gagcaaacta ggaaactagc
     3841 cgcaggttgc tcaaagcact gctttgaggt tgtagataag actgacaaag tcagtcacat
     3901 atatacggca aggcgacgtt gacgcggttt gaagagattt tcgaagagta taaaaatcct
     3961 caagatactt tcttctatcc tttagtttat aaggagaata cctatgaaaa aaactgctat
     4021 ttctatcttt gctctcctaa tgttaggagt ttgctgcctg ttcctattca gccagcaaag
     4081 ctataaaaaa cagtcgttca atactatgct aacgaccaga acctgcccag taggataact
     4141 tatagtgaat atagcgacaa acgagaagcc aactacggta gcactctaaa catcacgtct
     4201 atcaaacaag ctaatgacgg agtttatgca acctatgaag ggcaattgac acctttccaa
     4261 tattgataaa ttgataacca gcctgtcttc atctagtcat gctggttttt aagttcattt
     4321 taaatcctta cctattctcc ctaactgtgc tatacttaat ttatactcaa tgaaaatcaa
     4381 agagcaaact agaaagctag ccgcaggctg ttcaaagcac tgctttgagg ttgcagataa
     4441 agttgacgca gtttgaagag attttcgaag agtattagta cattctttga gattggagct
     4501 agtatgaaaa tccataaaac cgtgaatcct gttgcctatg aaaataccta ttatctagaa
     4561 ggcgaaaagc acctcatcgt cgtcgatcct ggtagtcatt gggaagccat tcgtcagaca
     4621 atcgagaaga tcaacaaacc gatctgtgct attctcttga cccacgccca ttatgaccat
     4681 atcatgagtc tggacttggt tcgcgagacg tttggcaatc ctcctgtcta tatcgcagag
     4741 agcgaagcca gctggctcta cactcctgtc gataatctct ccggtctccc tcgccacgat
     4801 gatatggcag atgtggtcac aaaacctgca gaacacacct ttgtctttca cgaagaatac
     4861 caactagagg aatttcgttt taaggttcta ccgaccccag ggcactctat cggtggtgtt
     4921 tccctagtct ttcctgatgc tcacctagtc ttgacgggag atgctctatt ccgcgaaact
     4981 atcggacgga ccgaccttcc gactggtagc atggagcaac tccttcatag tatccagacc
     5041 caactcttca ccctaccaaa ctacgatgtc tatccaggac atggtccagc tactactatc
     5101 gctcacgaaa aggccttcaa tccctttttc tagcaagatg atgacaatcg aaatttaagt
     5161 aaactatcca gcaaatcttt ctattacaaa aggcatccta tcaaggtttt cacacgtgat
     5221 tggatgcctt ttttctgatg actagatttt ttgtattacc aaataatcac gcgctcctct
     5281 ggtgaacgcc acattccgtc tccttctttg acatcatagg ttgtaaagaa atcgtcgaag
     5341 tttggtactt gcacattgac acggagtttg gctggtgcgt gcacatcgac gctagccaaa
     5401 agtttcataa attctggtcg acctttcatg cgccagatgc gaccgaagtt gtagaagaac
     5461 tcttctgctg agaagtctgc ttctctctta gctgcttcaa gcgctgctgc gattcctccc
     5521 aagtcagcca cgttttctga tacagtcaat ttaccgttaa tggttgctcc ataagaatcc
     5581 tgtccatcaa attggtcaat gactttttgt gttttctcct tgaaggcagc atagtcgctc
     5641 tctgtccacc aatccttgag gctaccattt tcgtcaaagg aagccccgtt agtatcaaag
     5701 gcgtgggaaa tttcatgggc aatcactgcc ccaataccac cgtagttagc agaagatgac
     5761 tgatgcaagt catagaaagg cgcctgtaaa atggccgctg gaaagacaat caggttcttc
     5821 tgaggattgt agtaggcatt gaccatatga gcaggcatgc cccattcctt atagtctaca
     5881 ggctggttcc acttactcca actgtgcttg atttccacac gcgcaaaggc tagagcattc
     5941 tcaaaaagac tggcagtttc attcactacc ttatccttgt aacgtgcagg caattcttct
     6001 ggatagccaa tataaggttt gatcacattg agcttcacga tagcctgttt acaggtttct
     6061 ggagtgagcc agtcattctt aagcagacgc tccttataga catcaatcat ggttgccact
     6121 tttttctcca catccgcctt ggcttctgga gagaacttct cacgggcgta ccaaagcccc
     6181 agggcttgct tgaaaggttc ctgtgctaga tgataagctg ctttgacctt atcttttgcc
     6241 tctggaactc cagaaagggc acggctgtag gcaccagaca aaacacggat atcctctgtt
     6301 aaatagctgg ttgaaagatt gacaacactc aaaatcaagg ttgctttaag gagagaccag
     6361 gcttcctcac tgtaaaattg ctctgctgct tgccagaaac gttcctcgtc tacaataacc
     6421 ttgtctggta attgcccaat aactgctttg aagaagtcat ccaaaggtag ggcaggcgcg
     6481 aatttcttga aatcttcgta agaatatgga tgatagagtt tagcatattc tgaactttct
     6541 tcattagaga gcaccactgc cacaactcgg cggtccaatt caagtctttt ttctagcaag
     6601 tcttcaattt cttcatcaga gaaatcataa gccttgagga gatttgcgct gctttctttc
     6661 caaagagtca agagctcttc gcgctgagga tgttcttctg catagtaggt cgtatctggc
     6721 aagattgtgc ttggagcgct agcccataga acattgattc tagcatccat aaagtctggc
     6781 gatacaccaa aaggaaggaa gtttggtttt cctgcaagct caaactctgc tagtttagct
     6841 gtaaaatccg caaaagtttc caattcttgg aattctttaa ggagtggtaa gacaggtgtg
     6901 ataccgtcag cttctctctt gtcaaaatca cgaactaggc ggtggtattt gacaaagttt
     6961 tccaagatag catcctcagg cacttcttca cctgctaacc acttgtctgt tgtcgccagc
     7021 atcaggtctt caatttcctg gtctaaatca acaaaacctc ctgtttgaga cttatctgct
     7081 gggatttcag ctgtctgttg ccattctcca ttgatagcat cataaaaatc atcttgataa
     7141 cgtgtcatct tgttctcgct ttcatttgta tttgcattta tcttaacaaa aatcactagg
     7201 gaatgcaatt aataaccatt taactattat tttttagcta ttataaaaaa tctttccatg
     7261 ataaaa
//
LOCUS       DAVHSY010000065         6936 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.066, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000065 DAVHSY010000000
VERSION     DAVHSY010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6936
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.066"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(116..391)
                     /locus_tag="VVR43_001919"
     CDS             complement(116..391)
                     /locus_tag="VVR43_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU6150230.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(498..1337)
                     /locus_tag="VVR43_001920"
     CDS             complement(498..1337)
                     /locus_tag="VVR43_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU6150231.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILCHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1479..2327
                     /locus_tag="VVR43_001921"
     CDS             1479..2327
                     /locus_tag="VVR43_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU6150232.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2420..3337)
                     /locus_tag="VVR43_001922"
     CDS             complement(2420..3337)
                     /locus_tag="VVR43_001922"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU6150233.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3775..3980
                     /locus_tag="VVR43_001923"
                     /pseudo
     CDS             3775..3980
                     /locus_tag="VVR43_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4185..4478)
                     /gene="rpmA"
                     /locus_tag="VVR43_001924"
     CDS             complement(4185..4478)
                     /gene="rpmA"
                     /locus_tag="VVR43_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU6150234.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4495..4839)
                     /locus_tag="VVR43_001925"
     CDS             complement(4495..4839)
                     /locus_tag="VVR43_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU6150235.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4855..5169)
                     /gene="rplU"
                     /locus_tag="VVR43_001926"
     CDS             complement(4855..5169)
                     /gene="rplU"
                     /locus_tag="VVR43_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU6150236.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5205..5292)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5357..6055)
                     /locus_tag="VVR43_001927"
     CDS             complement(5357..6055)
                     /locus_tag="VVR43_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU6150237.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     gene            6457..6756
                     /locus_tag="VVR43_001928"
     CDS             6457..6756
                     /locus_tag="VVR43_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU6150238.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2186 a         1410 c         1146 g         2194 t
ORIGIN      
        1 atacaatatt ttcggaacat tcaacttttt aactctattt attactagat ttcataatta
       61 aaaagcctac tgaccaagct agaaagcttg atacaatagg ctttttaaag actgattatt
      121 taacagcgtc tttaagagct ttaccagctt tgaatgctgg tactttagaa gctgcaattg
      181 tcatttcttt accagtttgt gggttgcgac ctttacgttc tgcgcgctca cgaacttcaa
      241 agttaccaaa accgatcaac tgaacttttt caccagctgc aagatagtca gctactgctg
      301 caaatacagc ttcaactgct gctgctgagt ctttcttagt caattctgta gcttctgcta
      361 ctttagcgat caaatcttgt ttgtttgcca tgttaatgat tcctccaaat aatttctaat
      421 taacaaatat aatcatatcc taaaatccct tttaggtcaa gttaaaaacg ctatttcttc
      481 ccattttatt tattttttta ggagtggtaa cgtatcaaaa tagcccaagc gttctcaccc
      541 gtgtgagttt gaataatgga acccgtttcc aaaacagaaa ttggcttttc aacataagct
      601 tgtaagcttt ctttcatctc ttttgcccaa tcatcactac cagaatatga aattccaatc
      661 tctgctacag cacgttcaga aagcgatgtt atcaactcat ctaaccattt tttaaatgtt
      721 ttagttccac gacctttaac cattggctgc aattcatggt ctttcatttg catgacaaca
      781 cggatattga gaagagagct caacaagcca gttacacggc taattcgtcc acctttgaca
      841 agattttcca aagttgaaac accaatataa agctctgtat ggtttttaac ctcttctaca
      901 tgacataaaa ttgcctccat atctttacct tcttgagcta acttcgcagc ctcaacaact
      961 tggaatttca gggcttggtc agtgaaggaa ctatcaacaa cagtcacatc tgcagtagat
     1021 aggctagcac cttggcgtgc tgcttctacc gtacccgaaa gagcatggga catatgaata
     1081 gcaagaatct ggccaccatc tttgcatagg tcttcaaaaa tctcagcaaa gacacctaca
     1141 ggtggctgac ttgttttcgg aagattctta ctttcttgca tcaactgaag aaatttacct
     1201 tcttctttca aatccgcatc agaataaaca acattatcaa tcattacaga taatggaaca
     1261 attgtaatat ctaattgctt tactagttca ggttcaatag taacagatga atcggttaca
     1321 atcttaattt ttgtcatagt atcaatcttt ctattttagg attcagattg gtttccttac
     1381 ttctaattat atcaaaaaaa agattaaaaa tcctaatgga gtcaatcaaa ttttccgtaa
     1441 aatttgatat aatcaactta taagaaaaga ggtgtcctat gattaaaaaa atttacccca
     1501 tttttaccat tttactaggt gctgctattt atgcttttgg actgacttat tttgtagttc
     1561 cccatcatct ctttgaagga ggggcgacag gcattaccct catcaccttt tatcttttta
     1621 aaatccctgt ttccctcatg aacctgctga ttaatattcc ccttttcatc ctagcttgga
     1681 agatctttgg agccaaatcc ctctattcta gtttactagg aaccttagct ttgtccgcct
     1741 ggttagcttt ttttgagcat attccccttc atattgatct tcaaggtgat ttactaatca
     1801 cagcccttat agcgggaatc ctattgggaa ttggccttgg aattattttt aatgctggag
     1861 gtacaactgg cggaactgat attctagctc gtattctcaa caaatacact catatatcca
     1921 taggaaaact gctctttatc ttagattttt gtattctcat gttgattctc ctaatcttca
     1981 aggatttgag attggtttcc tacacgcttt tgtttgattt tattgtttct cgtgttattg
     2041 atttgattgg tgaaggagga tatgccggca aaggctttat gattatcaca aaacgtcctg
     2101 accaacttgc taaggcgatt aatgatgacc tcggaagagg tgttactttt atttctggtc
     2161 aaggctacta tagtaaagaa aatttgaaaa tcatctactg tattgtcgga agaaatgaaa
     2221 ttgtgaaaac gaaggaaatg attcatcgaa tcgatcctca agcctttata actattacag
     2281 aagcccatga aatcctagga gaaggcttca cctttgaaaa agaataaaaa gaggtaatgt
     2341 cgtgacctca aaagttagac taaatcatct atcttttggg ttacagacaa cctctttttt
     2401 attttattta ctcaagctct taagaccaat tccgagttac ttcttcatca gcctttaact
     2461 gatccactaa ttggtcaact gagtcaaatt tggtcatatc acgaatgcga tcaagccaat
     2521 aaaccatgac ggtttcccca taaatatctt gattaaaatc aaaaatattg acttcaaaac
     2581 gtgcttcttc tccatcaaag gtcacatttt tcccgacact agccatagca cgatacttct
     2641 gtctttgaat ctcaacatca acgacataaa cgccatctgc tggcatataa gtacggtcta
     2701 aaagcactaa attcgctgtc ggataaccaa ttgtacgacc acgagcatta ccatgaacca
     2761 ccatacctct tgatggaagc ggtgccccca aaagttttcc tgcttctttc acatttccat
     2821 ctaaaatagc ttgacggata cgagttgaac taatctttcc tttctcatct tctacaggtg
     2881 gaacaatgat aacttctcca tcaaagtaat cctttaaatc ttctgctgtt tttttgtcag
     2941 aaccaaatgt ataatcaaaa cctgcaacaa taattttggc attcatagcc ttgatataag
     3001 ttgcaaagaa ttcttgtgca gtgagactag cgaattgact actaaaatca aggagatata
     3061 attcttctac accttcgcgc tttaattttc tttcacgttc agcagggttc aaaatatgca
     3121 aaaacaaatc tggatgataa ggctctaaag cgatctttgg agattcatta aaggtcataa
     3181 cgacgatagg taataaatcc tttctcgcag ccttgttggc aacacgaaat aattcttgat
     3241 gccccttatg tatgccatca aaatagccga gaacaacgac tgaatcagat ggtgtgccaa
     3301 tatctttttg gttttttata ggaatagtaa taatcataaa ataattatat catagcgata
     3361 gctatttctg gaacagaaaa tctgaaatgt tgtttttttc acatgaagtg tacctgtttt
     3421 caaaaagcac tttattctat cgttgcttaa ctatgaactt tgcaatattc ttctcaaaaa
     3481 cttgtaggac atcttcaaaa ttttgcaagg agtgattaga cttgttcggt aaccataaag
     3541 tgtcatacta tgcttatgta tgaaaaagca atgcaactaa ctcctgagaa ctttaaatta
     3601 ctaattggtg ccgaaaaggt agaatttaga atcgaggtac acctatggct gtaaaattta
     3661 caaaatgaga caacttgggc aagatgtttg aagaatttcc taaactccct gatttgaagc
     3721 aagtcacttt ccctgatgac aaagaaaaaa gccaaaacag caaagaaaaa ctagatgact
     3781 gctttccaac aactcccatc tagtgtgctt cagactgggc tatttttctc tccatctgtt
     3841 agcttggatt ctcagacagt ttcagctaaa gaatatcttt tcccttatca gaaggaacgg
     3901 ctcaaaccat tcagacaagt gaagggacga caagccaata tttgaaacca gatagcagtt
     3961 cttatagtca attgaaataa aatctgaaga aatcgagtag gaaactcata tcaattttta
     4021 acagtgttct attccagatt caatccacta tacatattaa aaagtatggg taccaaaaca
     4081 aaaaaacagg ctctccgaaa actcggaaag ccttatttta agctgtttct agcttcctca
     4141 cctttacatt tcaaggttcg ggataaaagg ttcaatggac ctttttattt agcgattggg
     4201 taaacagaaa cttgtttttt atcgcgtcct ttacgttcaa agcgtactac gccttcaact
     4261 ttagcgaaca aagtatcgtc tccaccacga ccaacgttta cacctggata gatgtgtgta
     4321 ccacgttgac ggtaaaggat tgatccacct gttacagttt gtccgtcagc tgctttagct
     4381 ccaagacgtt ttgcttgtga atcacgtccg tttgatgtag aacctccacc ttttttgtgg
     4441 gcgaaaagtt gcaagttgtt aagagtcatt tttaacataa tgttttcctc cgtgttagtt
     4501 ttctgtgata actctggttt ggacgaactc agaatagttc tccgataagt ttgccatacc
     4561 taagaaaaat gattcaaaga ataactgggt catttctctc tggtgtgaag gaagatcttt
     4621 tggtatttca accatcagat agccaccttc atcttcgttt aattctagga ttggttcata
     4681 gcctgcaaat ttctcaatag aattgataaa gttaatggca agcgtagaaa ccgatgcaca
     4741 cacgacatct aagccgtatt cgccactctc ggcgtgtcca gtaatttccg cactcctcag
     4801 ctcgccatct tcggctctct caaagactgc ctgtatcatg tgttctcctt aaaattaagc
     4861 gttgattgcg ttgatgacaa cttttgtata tggttgacgg tgaccttgtt tacggtggct
     4921 acctttttta ggtttgtact tgtaagtaac cactttcttt tgttttcctt gtttttcaac
     4981 agttccaact acagtagctc cagcaacaag tggagttccg acaacagtat tttcaccacc
     5041 aacaagaaca acttcgttaa aagtaacttc ttgaccagct tcaacgttca atttttcaac
     5101 gtaaactgct tgaccaactt caactttaac ttgttttccg ccagttttga taattgcgta
     5161 tgtgctcatt atgcacctcc tatgattttt atgggtttcc ccgatttttt gtgaagactc
     5221 gcctagcatc gtgggacgaa ccacttaaac ttgaataatc aagcaacgat gttcgtgcgg
     5281 ttgcacagga tcgtgcatag tcaactcttc aagtatagca tatctcctat tttcttacaa
     5341 gtaataacac ctaaaatcaa gctttttctt ttactttttt ctgccaagag gcaaaaagca
     5401 tgctgaggta aaaaacgctc atcataatag gaacaccaag aatggtcttt tcatgataga
     5461 aaatcgtcaa ataggctgaa aagacaacgc caaggacaaa actactaagc aggctaacaa
     5521 atatgaatcc ttcacgcaaa aaaggagtgt gcttggttcg gaaataatct ccaaaagcca
     5581 gcatggtccg tttgatattc cctgtcataa aagcgttatt ataggcaata cccgacactt
     5641 ctccaaaagc agttgtcacc agtcccatac agaaggccaa gggcggcact agatagatat
     5701 tatccacagt ttgcggcaca aaagcaataa tgattgataa gattgccaag ggaatcaagg
     5761 acagaatagg ttttttcaca attctcaatt tttccttata aatcgttaat aaaaagactc
     5821 ccatcataaa cgctagcaag gtgagaacct tgtccctaac atccgaaaca ttatttttaa
     5881 ttaattctac tgaaagaaag acaacatttc cagtttgtcc agctacaagg gtattcccgc
     5941 gaacaataaa agtgtaagca tccacatatc cagcacaaaa cgtcaaaaaa agtgctaacc
     6001 ttttagactg acgtgatatt tttcttatag gtaataacct cattttccct cccattgtat
     6061 tttctcttag aaatattgta ccatttcttt ctaaaaaatc gtagactacc atttagattt
     6121 tactattagc ataaaaataa taatagacaa ctatttatcc aaaaatagat agaggtaaca
     6181 tgtttgcaaa caaagcatac gaatctttag taaaatcatt tccatgaaac tagaatagag
     6241 cccctcttag caaaaatcat tattttaatt tatttctaat cactccttga cataaataac
     6301 tctcaccaat aaaagactat gtcttaaaaa aatggtataa taaaatcaat acttgggctt
     6361 gatggctatg ctactaataa caattaggag agaaaatcag gcacttgtta acaacaagga
     6421 ttatcccctt gagatgaaag gaactttaga aatcttatga tgaacatgca aaacatgatg
     6481 cgtcaagcac aaaaacttca aaaacaaatg gaacaaagcc aagctgaact tgctgctatg
     6541 caatttgttg gcaaatctgc tcaagatctt gtccaagcga ccttaactgg cgataagaaa
     6601 gttgtcagca ttgatttcaa tccagctgtc gttgacccag aggaccttga gactctttct
     6661 gatatgaccg ttcaagccat caactctgct cttgaacaaa tcgatgaaac taccaagaaa
     6721 aaactgggtg ctttcgctgg gaaattacct ttctaaaaac aaggagctag aacaatgctt
     6781 gtcgataaca aaggctaaga aaggtgcaaa aatgactcta taatatttgt agtgggtaaa
     6841 tccactatag atattatgga gcctatttta ttgtagaaaa aaagggctct ataatatttg
     6901 tagtgggtaa atcccctatg gatattatgg agctta
//
LOCUS       DAVHSY010000066         6923 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.067, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000066 DAVHSY010000000
VERSION     DAVHSY010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6923
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.067"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            1..510
                     /locus_tag="VVR43_001929"
                     /pseudo
     CDS             1..510
                     /locus_tag="VVR43_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            571..1533
                     /locus_tag="VVR43_001930"
     CDS             571..1533
                     /locus_tag="VVR43_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU6150239.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETISKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIA
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1713..2720
                     /gene="gap"
                     /locus_tag="VVR43_001931"
     CDS             1713..2720
                     /gene="gap"
                     /locus_tag="VVR43_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU6150240.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2789..3625)
                     /locus_tag="VVR43_001932"
     CDS             complement(2789..3625)
                     /locus_tag="VVR43_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU6150241.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLSHHNFPILGDPLYNSNSKTSRLMLHAFRLSFTHPLTLEKLNFTALSNTFETELKK
                     NG"
     gene            3751..5946
                     /locus_tag="VVR43_001933"
     CDS             3751..5946
                     /locus_tag="VVR43_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU6150242.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENISLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTSGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5999..6151
                     /gene="rpmG"
                     /locus_tag="VVR43_001934"
     CDS             5999..6151
                     /gene="rpmG"
                     /locus_tag="VVR43_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU6150243.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6161..6337
                     /gene="secE"
                     /locus_tag="VVR43_001935"
     CDS             6161..6337
                     /gene="secE"
                     /locus_tag="VVR43_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU6150244.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6392..>6923
                     /gene="nusG"
                     /locus_tag="VVR43_001936"
     CDS             6392..>6923
                     /gene="nusG"
                     /locus_tag="VVR43_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU6150245.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         2161 a         1213 c         1489 g         2060 t
ORIGIN      
        1 ccagaaaaag tagccttatt tcttaaaaat tttaatagtt taaagcacct agcacctgtt
       61 tagattgatg aaacaggatt cgatacttat ttttatcgag aatatggtcg ctcattaaaa
      121 ggtcagttaa gaagaggtaa agtatctgga agaagatatc agaggatttc tttggttgca
      181 ggtctaacaa atggtgagtt aatcgctcca atgacttacg aagagatgat gacgagcgac
      241 ttttttgaag cttggtttca gaagtttctc ttaccaacat taaccacacc atcggttatt
      301 attatggata atgcaagatt ccatagaatg ggtaagttag aacttttatg cgaggagttt
      361 gggcataaac ttttacctct tcctccctac tcacctgagt acaatcctat tgagaaaaca
      421 tgggctcata tcaaaaagca cctcaaaaag gtattaccaa gttgcaatac cttttacgag
      481 gcttttttat cctgctcttg tttcaattga ctatagttca cggatacagt tgggaaagaa
      541 gctattaaat atttggagag tccttttggg atgaacatgt caaatattac tatagatggg
      601 caagaaatgg atctgagtca aacgatgcct tcttatgctc aagtagtgag tctttatgat
      661 gatacaagta tctctgttag taataatgag acggacaaag tgttggctgg ctccctctat
      721 actgatacaa atgaacaggg attaacgatt ccaagcagtt tactaaaaaa ttggaatgaa
      781 cagacaggaa aaaatttgac agctaatgat cttattggca aatcagtctc agccagcatt
      841 gtagaaagtg ctgccgaaac tagtaagatt gctcaatttc aaacgaagat tgtacgtgta
      901 atcaatgatg aagatgacat ggaggacagc aacagtttca tgctgtctca tcaaatggaa
      961 acgatttcga aagaggctgg atttacgaaa gctgtatctt attttatctt ggaactcaaa
     1021 gatccatcac agacaaaagt agtaacagaa gaattacaga aaaataagaa gtatactgtg
     1081 ctttctcaac agagagttct tgatattgtg attaccttta ttcgtgttat tcagggatta
     1141 ttgattgtgc tttcatcaca agctattgtg gtagcagcgg ttatgattgg tatcattatt
     1201 tacatcaata tcatgcaacg ttccaaggaa ataggtgtca tgaaggcagt tggctatcag
     1261 aatcgtgatg tcaaaggaat ttttatttac gaggctatct ggattgtagg aatcgccttg
     1321 ctactggctt ttttggtagc acaaggggtg ggaagtttag cgaatgcgat tgtaagtcac
     1381 ttttacccat ccatcgctaa ggtctttgaa ttaaatttgt tatctgtttt aggaactcta
     1441 gttttcgctc tcttgcttgg ctatgtatca gcctacttcc cagcacgtaa aattagtaaa
     1501 atggaccctg tagaatcgct acgctatgaa tagtcaaggg tgttactaga ttatcgtccc
     1561 taaaaaagaa actaacagag aaaaacaatg cccgtacttg caattcaact caaatagtta
     1621 tataataggt ttgttgaaag gtgatttgta gtgattcaag ttactctttt cacaataaaa
     1681 atttcatgat tttcataagg aggaaatcac taatggtagt taaagttggt attaacggtt
     1741 tcggacgtat cggtcgtctt gctttccgtc gtatccaaaa cgtagaaggt gttgaagtta
     1801 cacgcatcaa cgaccttaca gatccagtta tgcttgcaca cttgttgaaa tacgacacaa
     1861 ctcaaggtcg tttcgacggt actgttgaag ttaaagaagg tggattcgaa gttaacggta
     1921 aattcgttaa agtttctgct gaacgtgatc cagagcaaat cgactgggct actgacggtg
     1981 tagaaatcgt tcttgaagct actggtttct ttgctaagaa agaagcagct gaaaaacacc
     2041 ttaaaggtgg agctaaaaaa gttgttatca ctgctcctgg tggaaacgac gttaaaacag
     2101 ttgtattcaa cactaaccac gacgttcttg acggtactga aacagttatc tcaggtgctt
     2161 catgtactac aaactgcttg gctccaatgg ctaaagctct tcaagataac tttggtgttg
     2221 ttgaaggatt gatgactact atccacgctt acactggtga ccaaatgatc cttgacggac
     2281 cacaccgtgg tggtgacctt cgccgtgctc gcgctggtgc tgcaaacatc gttcctaact
     2341 caactggtgc tgctaaagct atcggtcttg taatcccaga attgaacggt aaacttgacg
     2401 gatctgcaca acgcgttcca actccaactg gatcagttac tgaattggta gcagttcttg
     2461 aaaagaacgt tactgttgat gaagtgaacg cagctatgaa agcagcttca aacgaatcat
     2521 acggttacac agaagatcca atcgtatctt cagatatcgt aggtatgtct tacggttcat
     2581 tgtttgacgc aactcaaact aaagttcttg acgttgacgg taaacaattg gttaaagttg
     2641 tatcatggta cgacaacgaa atgtcataca ctgcacaact tgttcgtact cttgaatact
     2701 tcgcaaaaat tgctaaataa ttcttgaatc gataaaaagc aaggcctctt ggtcttgctt
     2761 ttcttatatg gaaaaatgga tgacacaatc atccattctt ttttaattct gtttcaaaag
     2821 tatttgagag ggcagtgaag tttaattttt ctaatgtaag tggatgggta aaggaaagtc
     2881 gaaaggcatg aagcataagc cgacttgtct ttgaattgct gttatagaga gggtcgccca
     2941 aaatagggaa gttatgatgc gaaaggtgca cacgaatctg atgggttcgc cctgtcttta
     3001 gcttgcaatg agccaaggaa gtcttgtttg agaattgctt taatctgctt acatacgttt
     3061 cagcatattg cccatttttt gcatcaacta ttctttttct acgatcatgg cgatcacgtc
     3121 caattttgtc tctgaaaaca agttcttttc tgttgatatt tccatcaact agagcccaat
     3181 attctctaga aatctctttt ttctccaata agcgattgag aatgggcagg ataaaaggat
     3241 ttttggcaaa gagaactaag ccactggttt ccatgtccag acgatgaacg acatagcagg
     3301 tttggccaac ataggtactg acatggttaa gaagggcaat ttcgtttggt tgattaccat
     3361 gcgttttcat cccctctggt ttgtttacaa taatcaagtg ttgatcttga taaacttcct
     3421 gcactaagtc tgggttgccc caagggatcg tcttttggga ataatcttcc tcgtcaaaag
     3481 tcaactggca aacatctcca ggatttacga tttcgttcca gtggacttct tcttgattta
     3541 tcaaaatatg tttcttgatt ctcaaaaaat gacggatttt tctagggatg aggagttgtt
     3601 cctcaagtaa ttgctttacc gtcatttgag gtagagaggc gggtaatgta aatgtgaatt
     3661 gcatacagat attgtaacaa aaaaagccct atttggatag gaaatagcta aattcttgtc
     3721 ttcctatgat gaagatgata aaataaacgc atgaaattag ataaattatt tgagaaattt
     3781 ctttctcttt ttaaaaaaga aacaagtgaa ctagaggact ctgattctac tatcttacgt
     3841 cgctctcgta gtgatcgaaa aaaattagcc caagtaggtc cgattcgaaa attctggcgt
     3901 cgttatcatc taacaaagat tatccttata ctaggtttga gtgcaggatt gctagttgga
     3961 atctatttgt ttgctgtagc caagtcgacc aatgtcaatg atttgcaaaa tgccttgaaa
     4021 actcggactc ttatttttga ccgtgaagaa aaagaggctg gtgccttgtc tggtcaaaag
     4081 ggaacctatg ttgagctgac tgacatcagt aaaaacttgc agaatgctgt tattgcgaca
     4141 gaagaccgtt ctttctataa aaatgacggg attaactatg gccgtttctt cttggctatt
     4201 gtcactgctg gacgttcagg tggtggctct accattaccc aacagctggc taaaaacgcc
     4261 tatttatcgc aggatcaaac tgttgagaga aaagcgaaag aatttttcct tgccttagaa
     4321 ttaagcaaaa aatatagtaa ggagcaaatt ctaaccatgt accttaacaa cgcttatttt
     4381 ggaaatggtg tgtggggtgt agaagatgcg agtaagaaat actttggagt ttctgcatca
     4441 gaagtgagtc tggatcaagc tgcgactctg gcagggatgc tcaaggggcc ggaactgtat
     4501 aatcccttga attctgtaga agattctact aatcggcgcg atactgtctt gcagaatatg
     4561 gttgcagcag gatatattga taaaaaccaa gaaaccgaag ctgctgaagt tgatatgact
     4621 tcgcaattgc acgataagta tgaaggaaaa atctcagatt accgttaccc ctcttatttt
     4681 gatgcggtgg ttaatgaagc tgtttccaag tataatctaa cagaggaaga gattgtcaat
     4741 aatggctacc gcatttacac agagctggac caaaactacc aagcaaatat gcagattgtt
     4801 tatgaaaaca tatcgctatt tccgagggca gaggatggaa cgtttgctca atcaggaagt
     4861 gtagctctcg aaccgaaaac agggggagtt cgtggagttg tcggtcaagt tgctgacaat
     4921 gataaaactg gattccggaa tttcaactat gcaacccaat caaagcgtag tcctggttct
     4981 acaattaagc ctttagttgt ttatacgcca gcagttgaag caggctgggc tttgaataag
     5041 cagttggata accataccat gcagtatgac agctataagg ttgataacta tgcagggatc
     5101 aaaacgagtc gagaagttcc tatgtatcaa gccttggcag aatcgcttaa tctacctgct
     5161 gttgccactg ttaatgattt gggtgtcgac aaggcttttg aggcaggcga aaaattcgga
     5221 ctcaacatgg aaaaggttga ccgtgttctt ggtgtcgcct tgggaagcgg tgttgaaacc
     5281 aaccctcttc aaatggctca agcatacgcc gcctttgcaa atgaaggttt aatgcctgaa
     5341 gctcatttta ttagtagaat tgaaaatgct agtggacaag ttattgcgag tcataaaaat
     5401 tcacaaaaac gggtgattga taagtctgta gctgacaaga tgaccagtat gatgttgggg
     5461 actttcacca acggtaccgg tattagttca tcgcctgcag actatattat ggcagggaaa
     5521 actggaacaa ctgaagcagt ttttaatccg gagtacacaa gtgaccagtg ggtaattggt
     5581 tatactccgg atgtagtgat tagccactgg cttggctttc cgaccactga tgaaaaccac
     5641 tatctagctg gctctacttc aaacggtgca gctcatgtct ttagaaacat tgccaatacc
     5701 attttacctt atacgtcagg aagtaccttt acggttgaaa atgcttataa gcaaaatgga
     5761 attgcaccag ccaatacaaa aagacaagta caaaccaatg ataatagcca gacagatgat
     5821 aatttgtctg atattcgagg gcgtgcgcaa agtctagtag atgaggctag ccgggctatc
     5881 tcagatgcga agattaagga aaaggctcaa acaatatggg attcgatagt caatctattt
     5941 cgctaagatg cttgtcaaag cctagctttc ttgttataat ggataagatg gaggcgttat
     6001 ggcactaaaa aaagcaagcc tagcttgtgc ggtttgtggt tcgagaaact attcaatcaa
     6061 gatcagcgga aaccccaagc ctacacgact agaagtaaat aaattttgta agcattgtgg
     6121 caagtacact acacatagag aaacgagata ggagagagcg atgcgtttta ttggagatat
     6181 ttttagactt cttaaagaca caacgtggcc aactcgcaag gaaagctgga gagattttcg
     6241 ttctatcatg gaatacacag ctttctttgt agtaattatt tacatttttg accagttgat
     6301 tgtttcaggt ttgattcgat ttattaacat tttttagaag attggtggag ttaattacac
     6361 tagaaatctt ctatttatga aaggaaatat catggatagt tttgataaag gatggtttgt
     6421 tttacaaact tattctggtt atgaaaataa ggtgaaagaa aatctattac aacgtgcaca
     6481 aacctacaat atgttggata atattctacg cgttgaaatt ccaacacaaa cagtgcaagt
     6541 tgaaaaaaat ggaaagagaa aagaagtaga agaaaatcgc tttccaggtt atgttcttgt
     6601 agaaatggtc atgacagatg aagcttggtt tgttgttcga aacacaccaa atgttacagg
     6661 atttgtcgga tcacacggga acagatcaaa accaactcca ttattggaac aagaaattcg
     6721 tgacattttg gtatctatgg gacaaactgt tcaagaattt gatttcgatg ttgagattgg
     6781 tcaaactgta cgtattattg atggtgcttt tgcagactac actggtaaga ttacagaaat
     6841 tgataataac aaagtgaaaa tgattatctc tatgtttggt aatgacacag ttgcagaagt
     6901 aaacctaaac caaatcgcag aat
//
LOCUS       DAVHSY010000067         6794 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.068, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000067 DAVHSY010000000
VERSION     DAVHSY010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6794
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.068"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            1..292
                     /locus_tag="VVR43_001937"
                     /pseudo
     CDS             1..292
                     /locus_tag="VVR43_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            459..659
                     /locus_tag="VVR43_001938"
     CDS             459..659
                     /locus_tag="VVR43_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150246.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            684..1100
                     /locus_tag="VVR43_001939"
     CDS             684..1100
                     /locus_tag="VVR43_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150247.1"
                     /translation="MKAALESLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1331..2038
                     /gene="ccdA2"
                     /locus_tag="VVR43_001940"
     CDS             1331..2038
                     /gene="ccdA2"
                     /locus_tag="VVR43_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU6150248.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2049..2606
                     /gene="sdbB"
                     /locus_tag="VVR43_001941"
     CDS             2049..2606
                     /gene="sdbB"
                     /locus_tag="VVR43_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU6150249.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKIVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2980..4371
                     /locus_tag="VVR43_001942"
     CDS             2980..4371
                     /locus_tag="VVR43_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU6150250.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4514..5431
                     /gene="adcAII"
                     /locus_tag="VVR43_001943"
     CDS             4514..5431
                     /gene="adcAII"
                     /locus_tag="VVR43_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU6150251.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5439..>6794
                     /gene="phtD"
                     /locus_tag="VVR43_001944"
     CDS             5439..>6794
                     /gene="phtD"
                     /locus_tag="VVR43_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEU6150252.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFEKNGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFY
                     NK"
BASE COUNT         2091 a         1248 c         1431 g         2024 t
ORIGIN      
        1 ccagaaaaag tagccttatt tcttaagaat tttaatagtt taaagcacct agcacctgtt
       61 tagattgacg aaacaggatt tgatacttat ttttatcgag aatatggtcg ctctttaaaa
      121 ggtcagttaa gaagaagata tcagaggatt tctttggttg caggtctaac aaatgaatgg
      181 tgagttaatc gctccaatga cttacgaaga gacgatgacg agcgactttt ttgaagcatg
      241 gtttcagaag tttctcttac caacattaac cacaccatcg gttattatag taaaatgaaa
      301 taagaacagg acaaatcgat caggacagta aaatcgaatt ctaacaatgt tttagaagtc
      361 tatatgtact attctagttt caatatacca taactgctcc tagtcaacct gcaagtcctg
      421 tcccagctcc aagctcagct ccgactcaag atcctagagt ggtagcaagc gcttcggcta
      481 gctcaacgag cacacaagct caagagcaag ttgacaagtc tgaacttcgt gccttgagtc
      541 aagagttaga ccaacgcttg aaagctttgg caacagtatc tgatccaaaa atcgatgcaa
      601 ccaaggctgt cctcctagat gctcaaaaag ctccggaaga tagtgccttg acagagtaag
      661 gtctgcgtac tgcagtagag tctgtgaagg ctgccttgga gtctctcaaa gatgtgaaag
      721 caaatgctag cgatagcaag cctgcacagg acaagaagga tgcaaaacaa ggaacggaag
      781 atagtaagga ttcagataag atgactgaaa caaactcagt tccagcagga gtgattgtgg
      841 tcagtctact tgccctccta ggcgtgattg ccttctggct gattcgccgt aagaaagagt
      901 cagaaatcca gcaattaagc acggaattga tcaaggttct aggacagcta gatgcagaaa
      961 aagcggataa aaaagtcctt gccaaagccc aaaaccttct ccaagaaacc cttgatttcg
     1021 tgaaagaaga aaatggctca gcagagacag aaactaaact agtagaggag cttaaagcaa
     1081 tccttgacaa actcaagtaa aacatgattt atgaaatgtc agacctaaaa gacattttcg
     1141 ttcacaaaag cagcgatgag taatccttgt cgttgctttt tggctatttt gggggataag
     1201 atccgccttg actagcaaaa gaaaagattg gtccaatagt gcccgatacg attttgcgta
     1261 gcagaaagct tacaaataaa attgaatata gtaaaatagg attagaatta ttaagaaagt
     1321 tggttcttta ttggaaacga tagtattttt aatctctgtt tttctagcag gtgttttatc
     1381 ctttttttct ccttgtattt ttcctcttct gccagtctat gctgggattt tattggatga
     1441 tcaagaaagt gcaaaaagct tttctttgtt tgggagaaag gttctctggt caggcttgat
     1501 tcgaacactt tgctttatcg ctggtatctc tctcattttc tttattctag gctttggtgc
     1561 tggttacttt ggtcatattc tctatgcaaa ttggtttcga tatggcatgg gagctattat
     1621 tatcattttg ggtcttcacc agatggaaat ttttcatttg aagaaattag aagttcaaaa
     1681 aagttttacc tttaaaaaat cagactctaa tcgttattgg tcagcttttt tacttggtat
     1741 tacctttagc tttggttgga caccttgtat tggtccagtt ttaagttctg ttttagcact
     1801 tgcggcttct ggaggcaatg gcgcttggca aggagcgatt tatactctca tttacactct
     1861 gggcatggcc cttcctttct tggtattggc actagcttca ggtctagtca tgccatattt
     1921 tagtaaaatc aagcgtcata tgatgctact aaagaaaatt ggtggtttcc tcattgtttt
     1981 aatgggaatt ttgttactat taggacaagt aaatgttcta gctggaattt ttgaataaag
     2041 gaggacaaat gaaaaaagta atgtttgctg gcttaagtct cttgtcatta gttgtattga
     2101 tggcctgtgg tgaggaagaa actaaaaaga ctcaagcagc acaacagcca aaacaacaaa
     2161 cgactgtaca acaaattgct gttggaaaag atgctccaaa cttcacattg caatccatgg
     2221 atggcaaaga agttaagtta tctgatttta agggtaaaaa ggtttacttg aagttttggg
     2281 cttcatggtg tggtccatgc aagaaaagta tgccagagtt gatggaacta gcggcgaaac
     2341 cagatcgtga tttcgaaatt cttactgtca ttgcaccagg aattcaaggt gaaaaaattg
     2401 ttgagcaatt cccacaatgg ttccaggaac aaggatataa ggatatccca gttctttatg
     2461 ataccaaagc aaccaccttc caagcttatc aaattcgaag cattcctaca gaatatttaa
     2521 ttgatagcca aggaaagatt ggaaagattc aatttggtgc tatcagtaat gcggatgcag
     2581 aagcagcatt taaagaaatg aactagaatc gataaaatct gattacaaga tgtagtcaga
     2641 ttttggtaac ttctaaaact aacttccagt ttcccacaac ctagctttta gtatgagaaa
     2701 aacgcgtgac atcagtggaa atccgtctta gactaacttc cactggtttt ctttttcttg
     2761 atatataagg gttcaaaagc gaaaagactc agaaaaagtg cacgacaaat agccctaaaa
     2821 cagagtcgtc ttagagtaac ttccagtttt gggagagaga tggaagttac tttgagaagt
     2881 tacggtagtc agattttttt agaaaaacat tttataaata ttcacatatc tcctatattt
     2941 atggtaaaat agaatcatca gtttattttg gagtcaaaga tgaatatatt tagaacaaag
     3001 aatgttagtt tagataaaac agagatgcat aggcatttga agttatggga tttgattttg
     3061 ctgggtatcg gagccatggt agggacaggc gtctttacaa tcacaggtac tgcagctgca
     3121 acacttgctg gcccagccct agtgatttca atcgttattt ctgccttgtg tgtgggatta
     3181 tcagccctct tttttgcaga atttgcctcg cgagtacccg ctacaggagg tgcctatagt
     3241 tacctctatg ctatcttagg agaattccct gcctggttgg ctggttggtt aaccatgatg
     3301 gagttcatga cagccatatc aggcgtagct tcgggttggg cagcttattt taaaggcttg
     3361 ctctctcaat acgggatagc ctttcctcag gctttaaatg gtacctttaa tcctcaagca
     3421 gggacatttg ttgatttatt gcctattctt gtcttggtct tggtgacttc gcttgtttta
     3481 ctaaatgcca aggcagcctt acgctttaat tcgattctag ttattttgaa attttccgct
     3541 ttagctctct ttgttttagt aggaatttgg aatattaagt ttgataattg gagcaatttt
     3601 gctccttacg gttttggaca aatctatgga gctagcactg gtattatggc tggtgcgtcc
     3661 ttgatgttct tcggtttttt gggatttgaa tccatctcta tggctgtaga tgaagtcaag
     3721 actcctcaaa aaaatattcc tagagggatt gtcttatcgc tttctatcgt aaccattctc
     3781 tatgccttgg tgacccttgt tttgactggt gtggttcact atagtcattt aaatgtcgat
     3841 gatgccgttg cctttgccct tcgtagtgtt gggattagtt gggcagccaa ctatgtgtca
     3901 ttagtggcta tcttgacctt gattacagtt tgtatttcga tgacctatgc cctatcgcgt
     3961 atgatttaca gtttagcacg tgacggctta gtgcctgctg cctttaagga actgacgaag
     4021 actagcaaga taccaaagaa tgctactatc ttgacaggtc tagcttcagc agtagcagca
     4081 ggaatgttcc cactagccag tattgcagcc tttttaaata tttgtacctt agcctacttg
     4141 atcatgttgg cttatggtct gattcgctta cggaaagaaa aaggaatgcc caaagctggg
     4201 gaatttaaaa caccattggt acctctgtta ccaattttat cgatcatcat ttgtttatcc
     4261 ttcatgttac agtataatat gaatacctgg attgctttcc tagttgcgtt gttagtagga
     4321 agtattattt acttcactta tggctataag cattctacca tagaagaata aagtgaaagt
     4381 ctattgagtt gttgacactc agcagatttt tatatgtgaa agaaatttca aattttttct
     4441 aaaaatatct tgacagatta aattttcagg agtagaatat ttactagtta attaaatggt
     4501 taaggagttg ttcatgaaga aacaaaattt atttttagtc ctgttaagtg tctttctttt
     4561 gtgcttgggg gcttgtggtc aaaaggaaag tcagacagga aaggggatga aaattgtgac
     4621 cagtttttat cctatctacg ctatggttaa ggaagtatct ggtgacttga atgatgttcg
     4681 gatgattcag tcaagtagtg gtattcactc ctttgaacct tcggcaaatg atatcgcagc
     4741 catctatgat gcagatgtct ttgtttacca ttctcataca ctcgaatctt gggcaggaag
     4801 tctggatcca aatctaaaaa aatccaaagt gaaggtctta gaggcttctg agggaatgac
     4861 cttggaacgt gtccctggac tagaggatgt ggaagcaggg gatggagttg atgaaaaaac
     4921 gctctatgac cctcacacat ggctagatcc tgaaaaagct ggagaagaag cccaaattat
     4981 cgctgataaa ctttcagagg tggatagtga gcataaagag acttatcaaa aaaatgcgca
     5041 agcctttatc aaaaaagctc aggaattgac taagaaattc caaccaaaat ttgaaaaagc
     5101 gactcagaaa acatttgtaa cacaacatac agccttttct tatctagcga agagatttgg
     5161 gcttaatcaa cttggtattg caggtatctc tcctgaacaa gaaccaagtc cacgacaact
     5221 aacagaaatt caggaatttg ttaagaccta taaggttaaa acgattttta cagaaagtaa
     5281 cgcttcttca aaagtagctg aaactcttgt caaatcaaca ggtgtgggtc ttaaaactct
     5341 gaatccttta gagtcagacc cacaaaatga caagacctat ttagaaaatc ttgaagaaaa
     5401 tatgagtatt ctagcagaag aattaaagtg aggaaagaat gaaaatcaat aaaaaatatc
     5461 tagcaggttc agtggcagtc cttgccctaa gtgtttgttc ctatgaactt ggtcgtcacc
     5521 aagctggtca ggttaagaaa gagtctaatc gagtttctta tatagatggt gatcaggctg
     5581 gtcaaaaggc agaaaatttg acaccagatg aagtcagtaa gagagagggg atcaacgccg
     5641 aacaaattgt tatcaagatt acggatcaag gttatgtgac ctctcatgga gaccattatc
     5701 attactataa tggcaaggtt ccttatgatg ccatcatcag tgaagaactt ctcatgaaag
     5761 atccgaatta tcagttgaag gattcagaca ttgtcaatga aatcaagggt ggctatgtga
     5821 ttaaggtaga cggaaaatac tatgtttacc ttaaagatgc ggcccatgcg gacaatattc
     5881 ggacaaaaga agagattaaa cgtcagaagc aggaacgcag tcataatcat aactcaagag
     5941 cagataatgc tgttgctgca gccagagccc agggacgcta caccacagat gatggttata
     6001 tctttaatgc ttctgatatc attgaggaca cgggtgatgc ttatatcgtt cctcacggcg
     6061 accattacca ttacattcct aagaatgagt tatcagctag cgagttagct gctgcagaag
     6121 cctattggaa tgggaagcag ggatctcgtc cttcttcaag ttctagttat aatgcaaatc
     6181 cagctcaacc aagattgtca gagaaccaca atctgactgt cactccaact tatcatcaaa
     6241 atcaagggga aaacatttca agccttttac gtgaattgta tgctaaaccc ttatcagaac
     6301 gccatgtgga atctgatggc cttattttcg acccagcgca aatcacaagt cgaaccgcca
     6361 gaggtgtagc tgtccctcat ggtaaccatt accactttat cccttatgaa caaatgtctg
     6421 aattggaaaa acgaattgct cgtattattc cccttcgtta tcgttcaaac cattgggtac
     6481 cagattcaag accagaacaa ccaagtccac aatcgactcc ggaacctagt ccaagtctgc
     6541 aacctgcacc aaatcctcaa ccagctccaa gcaatccaat tgatgagaaa ttggtcaaag
     6601 aagctgttcg aaaagtaggc gatggttatg tctttgagaa gaatggagtt tctcgttata
     6661 tcccagccaa ggatctttca gcagaaacag cagcaggcat tgatagcaaa ctggccaagc
     6721 aggaaagttt atcgcataag ctaggagcta agaaaactga cctcccatct agtgatagag
     6781 aattttacaa taag
//
LOCUS       DAVHSY010000068         6413 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.069, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000068 DAVHSY010000000
VERSION     DAVHSY010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6413
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.069"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(205..609)
                     /locus_tag="VVR43_001945"
     CDS             complement(205..609)
                     /locus_tag="VVR43_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU6150253.1"
                     /translation="MKKIFATKRNVFLVRLLLGQIPLVVSTYLFLSRQFLNFSLVFQF
                     LLVIINLASILATVYLTREMRIRKFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     AESYQQIIAYIGAVLCLLIMLLLIWGLKYYKK"
     gene            complement(639..827)
                     /locus_tag="VVR43_001946"
     CDS             complement(639..827)
                     /locus_tag="VVR43_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150254.1"
                     /translation="MAALNTSLTTNIKFGLVGTVGGRFAGYGMYVLGYPGDYLDITNH
                     RVVSAKTSHKSYQILEND"
     gene            complement(1054..1629)
                     /locus_tag="VVR43_001947"
     CDS             complement(1054..1629)
                     /locus_tag="VVR43_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000497530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6150255.1"
                     /translation="MFVGFLVYVIVATVGYTINQGDYFQNEHLFIIAKTFLISLSVAY
                     AKWFDMISLRRLTKKEVLLFIASFLLCVLVNIGYHSLFTVSSGAGYQHLEAASTGISL
                     SFIASATVFGPILEEFVFRGILQGVVFENSWLGLVLTASLFSFLHAPYDFPSFIYYLF
                     GGFMLGFAYKKSQKLSVAILVYICYNCLSFL"
     gene            complement(1649..1753)
                     /locus_tag="VVR43_001948"
                     /pseudo
     CDS             complement(1649..1753)
                     /locus_tag="VVR43_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_037603748.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2831..3040)
                     /locus_tag="VVR43_001949"
     CDS             complement(2831..3040)
                     /locus_tag="VVR43_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEU6150256.1"
                     /translation="MFNYKIVDNQELSNISGGGLGGDVVVGALSGAFQAGQSCIAGGP
                     QAYLICATGGAIVGGILAYGLRPPK"
     gene            complement(3056..3304)
                     /locus_tag="VVR43_001950"
     CDS             complement(3056..3304)
                     /locus_tag="VVR43_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEU6150257.1"
                     /translation="MNTKMMSQFSVMDNEMLASIEGGTDWGTVGKGAVYGAGIGVAMC
                     AVGGLLTGGSTWAMTAGCAWAGAKLGGSFTAIADNLWP"
     gene            3579..4837
                     /locus_tag="VVR43_001951"
                     /pseudo
     CDS             3579..4837
                     /locus_tag="VVR43_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            4848..6209
                     /locus_tag="VVR43_001952"
     CDS             4848..6209
                     /locus_tag="VVR43_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU6150258.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEITPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDTIVNKRARLPTGNPHQSILNRY
                     LIASQEQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLGNNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            6266..>6413
                     /gene="blpC"
                     /locus_tag="VVR43_001953"
     CDS             6266..>6413
                     /gene="blpC"
                     /locus_tag="VVR43_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU6150259.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPI"
BASE COUNT         2186 a         1328 c          988 g         1911 t
ORIGIN      
        1 atagaactat agtaaaatga aataagaaca ggataaatcg atcaggacag tcaaatcgat
       61 ttctaacaat gttttagaag tagaggcgta ctattctagt ttcaatatac tatactatac
      121 catattttgt ttcgcaggga atctattata aaagggtaag tattgcgaaa acacttaccc
      181 ttttctttta tacttcatta agctctactt tttataatac ttcaaacccc aaatgagcaa
      241 aagcatgata agcaagcaga gaaccgcgcc aatataagcg attatttgtt gataggattc
      301 tgctgctgtg atccctctat acaaacatat aatagacata aaacctgtca agccgataaa
      361 catgagttga ttggttctag gactaaccaa atcatcatct tcaaactttc ttatcctcat
      421 ttccctagtg agataaacag tagccaaaat agaagccaag ttaataatca ctaaaagaaa
      481 ttggaaaacc aaggaaaaat ttaaaaactg acgagataga aatagataag tagaaacaac
      541 caaaggtatc tgtcctaaca acaacctcac taagaaaaca ttgcgttttg ttgcaaatat
      601 ttttttcata cctaaactcc attacaatta aatgatatct aatcattttc taaaatttga
      661 taacttttgt gagatgtttt agcagaaaca actctatgat tggtgatatc tagataatca
      721 cctgggtaac caagaacata cataccataa ccagcgaatc ttcctccaac tgttccaacc
      781 agaccaaact tgatattagt tgtgagagaa gtattaagag ccgccataag aatgcgcaca
      841 tgattatcca accaaaccat ataatttttt gaaaagctac ctcttcccaa cctcctaaac
      901 ctccttcaac tttcgcaaaa atttcggtat ccataatctc aaattgtgac atcatttcat
      961 ttaatgttgt taatctaaac agtaatagta tccatttccc tattttttaa gattttttgt
     1021 ccaatattat gtcatattga ttacttacat atactacagg aatgataaac agttataaca
     1081 gatataaact aaaatagcca ccgatagttt ttgactcttt ttataagcaa agcccagcat
     1141 gaaacctcca aatagataat agataaacga aggaaaatca taaggagcat gcaggaaaga
     1201 gaagagagag gcagtcagta caagccccaa ccaagaattt tcaaaaacca caccttgaag
     1261 gattcctctg aaaacaaatt cctccagaat agggccaaaa actgtcgcgc ttgcaataaa
     1321 ggataaggaa attcctgtac tagcagcctc aaggtgttga tatcctgcac cagaagaaac
     1381 tgtgaaaaga ctatgataac ctatatttac cagcacgcaa agaagaaagc ttgcaataaa
     1441 aagtagaact tcttttttcg ttaaccttct tagcgaaatc atatcaaacc atttcgcata
     1501 ggcaacactc agtgaaatca agaaagtctt tgcaataata aataggtgct cgttttgaaa
     1561 ataatcacct tgattgatgg tatagcctac tgtagcgact attacataga ctaaaaatcc
     1621 aacaaacacg gcatgatatt tattaaacag gtttgagtcc tacgcttaaa taagcttcaa
     1681 tttctcctct ttcagcttca gataagtgat tgtattattg atttgtggta gaatagtttg
     1741 tggacatgtt catcttcctt tatactgttt ttcgcaactc tagtatatca gatgaacatg
     1801 tcttttgtgt tgcacttcat tttacaacag agcgaatata tttagttgta aaagtaccaa
     1861 ttatgatatt tttcgctctg cagaatagaa atatcatttg ctttcaaaat aatgattaac
     1921 acaatcatat ttatttgtta caaagatttc ttaactaact cctctctcag gctacataag
     1981 cgttctattc gtgtgtcctt ttttttatga acaatagtca ccgtttatat tttcatacta
     2041 ccatcctatc aaacaaataa tcaaaacaga caattctact ttcaattgtt caccccttcg
     2101 ctccacttcc actacagaag tttcctcact actatgggtt cggctgactt ctcatgattc
     2161 gttgttacta cgcttttagc gctcatgaga cctcacggga taagtcgtac atctttcctc
     2221 gtttactctc gtgatttacg catataggtt acgactacct ttttggactt tagagtttga
     2281 ggccccctta tccgctatat acgccttact atcacgttcc tgttcgtaga gccacgattt
     2341 cgctatccct tcctctccct gctacctcac gatagtcagg cttgggaatc gctattgggt
     2401 tcaccggtag caggtgccca ccgaggactt acacctcaga tatacgacat gcccgtcgta
     2461 catcaaaaaa gaaaggacga aattcgtcct ttctcgatct tagattttct tcaactcact
     2521 acagttgaca atgagccaaa ggatagctaa taacctattg aagtgtcaaa cgttgctaac
     2581 tccatttatc ttcaaattta aataggcaca ttatcggagt tatcagtaag aaaaaatcta
     2641 accagttcag ataattcata atataggata taataccagc cataacgaaa aggtacaaag
     2701 ctgtacgata tcctctcttt tggtttttat cagccttggt gttaaaaata atgtacacac
     2761 aacaaattgc aatgagtaca agctgaatca tagtttcatt taacatatta acactcattc
     2821 ctttttaaaa ctattttggt ggtctcaatc cataagctaa aatgccacct actatagcgc
     2881 cccctgttgc gcaaatcaag taagcttgag ggcctccagc aatacaagat tgtcctgcct
     2941 gaaatgcacc cgacaaggct cctacaacta catctcctcc caatccacct ccagaaatat
     3001 tacttaattc ttgattatct actattttgt aattaaacat aatttctatt cccttctatg
     3061 gccaaagatt atcagcaatt gcagtaaaag aaccaccaag tttagctcca gcccaagcac
     3121 agccagcagt catagcccat gtggaaccac cagtaaggag tcctcctacc gcacacatag
     3181 caactccgat acctgctcca tagacagctc cttttcctac tgttccccaa tcagttcctc
     3241 cctcaatgct agccagcatt tcattatcca taacagaaaa ttgtgacatc atttttgtat
     3301 tcatgacaaa tactcctttt ttatttttgt cttgttgcaa ctttgacaag tttagtatat
     3361 catttttttt ttaaattttt catccaaatc ttgaattgtc atcgaaacgt cttgaattag
     3421 cttttcattt gaaaccacct ctaaatgttt aaaaaaaaaa taatttctaa tcactttttt
     3481 accattcagg aagtttcaat gactattcaa gatttaataa aatatgaact tatttttatg
     3541 gcataatata cctatctact atatgaaagg aattgccaat gacttcttat aaacgtacat
     3601 ttgttcctca aatagatgcg agagactgcg gtgttgctgc cttagcctcg attgctaaat
     3661 tctatggttc agatttttct ctagctcact tgagagaact tgcaaagacc aataaagaag
     3721 gaacgactgc tcttggcatt gtaaaagccg ctgatgaaat gggctttgaa acaagacctg
     3781 ttcaagcaga taaaactctc tttgacatga gtgatgtccc ctatccattt atcgttcacg
     3841 ttaacaaaga agaaaaactc caacattact atgttgtcta tcaaacaaag aaagactatc
     3901 tggttattgg tgatcctgac ccttctgtaa aaatcaccaa aatgtcaaaa gaacgctttt
     3961 tctctgaatg gactggagta gctatttttc tagctcccaa acccagctat caaccccaac
     4021 caaactccaa tctgcgaagg tcgctaataa ccgtttgaac gaagtctatc tagtcgaatc
     4081 tgaatttcaa gttcaagaaa accctgttca ttcacatttt ttgatgggcg atattgaatt
     4141 tgatgacctt tcttataagt atggttttgg acgagatacc ttaacagata ttaatctcac
     4201 gattaaacaa ggagataagg ttagcctagt tggagttagt ggttctggta aaacaacttt
     4261 agccaaaatg attgtcaatt tctttgaacc ctacaaaggg catatttcca tcaatcatca
     4321 ggatattaaa aacattgata aaaaagtctt gcgccgtcat attaattacc taccccaaca
     4381 agcctatatc tttaatggct ctatcttgga aaatttaacc ttgggcggta atcatatgat
     4441 tagccaagaa gatattctaa gagcttgtga attagctgaa atccgtcaag acattgaaag
     4501 aatgcctatg ggctatcaaa ctcagctctc tgatggagct ggtctatcag gaggacagaa
     4561 gcaacgaata gccctcgctc gtgctctttt aactaaatct cctgttttaa tactagacga
     4621 agctactagc ggtcttgatg tcttgactga gaaaaaagtt atagataatc ttatgtccct
     4681 aactgataaa accattctct ttgtagccca tcgtctcagt atagccgaac gaactaaccg
     4741 tgtcattgtt cttgaccagg ggaaaatcat tgaagttggt agtcaccaag agttaatgca
     4801 ggcgcaaggc ttctaccatc atctgttcaa taaataagga gaatgtcatg aatcctaatc
     4861 tttttagaag cgtcgagttt tatcagagac gttaccataa ctatgcgaca gtattaatca
     4921 tacctctttc attattattt actttcatct tgattttctc ccttgttgcc acaaaagaaa
     4981 ttactgttac ttcccaaggg gaaatcaccc ctacaagtgt cattgcatct attcagtcga
     5041 ccagtgataa tcctatcctt gctaatcatt tagtggcaaa tcaagtagtt gagaaaggtg
     5101 acttactcat caaatactct gaaacaatgg aagagagtca gaaaactgcc ttagaaactc
     5161 aattacaaag acttgagaag caaaaagaag gacttggaat cttgaaacaa agcttagaaa
     5221 aagcgactga tcttttttct agcgaggatg agtttggcta ccataatact tttatgaatt
     5281 ttactaaaca atcccatgat attgaactgg gtatctcaaa gactaacact gaagtttcaa
     5341 atcaagctaa tcttaccaat agcagttcat cagccatcga acaagaaatt acaaaagttc
     5401 aacaacaaat tggagaatat caagagctga gagatactat cgtaaataaa agagctcgct
     5461 taccaactgg caatccgcac cagtcaattt taaatcgtta tcttatagcc tctcaagaac
     5521 aaacacaagg aacggcagag gagccatttt tatctcaaat taatcaaagt attgcaggtc
     5581 tggaatcatc tatcgcaagc ctcaaaattc agcaagctgg tatcggaagt gtagcaactt
     5641 atgataatag tttagcaacc aaaattgaag tactccgcac tcagttttta caaacagcct
     5701 cacagcaaca actaaccgtg gagaatcaat taacagaatt aaaagtacaa ctagatcaag
     5761 caacgcagcg cttaggaaac aataccttaa ccgctccaag taaaggtatc gttcatctga
     5821 acagcgaatt tgaaggtaaa aatagaattc caactggtac agaaattgct caaatattcc
     5881 ctgtcatcac agatacaaga gaagtactaa tcacttacta cgtatcttct gactatctac
     5941 ctctactaga taaaggacaa actgtaagat taaaactgga gaagattgga aatcacggca
     6001 ccaccatcat cggccaactt cagacaattg atcaaactcc taccagaaca gagcaaggta
     6061 atctctttaa attaaccgct cttgcaaaac tatctaatga ggatagtaaa ctcatccaat
     6121 atggcttaca aggtcgcgtc actagtgtaa ctgcaaagaa aacatatttt gattatttca
     6181 aagataaaat tttaacccat tctgattaat tttcagataa cactctataa ctatttatta
     6241 tcttatcaaa aaggagaatc ataacatgga taagaaacaa aacctaactt catttcaaga
     6301 actaacaact accgaactca accaaattac aggtggagga ctgtgggaag atatcttata
     6361 cagccttaat ataattaagc ataacaatac gaaaggactt catcatccaa tac
//
LOCUS       DAVHSY010000069         6207 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.070, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000069 DAVHSY010000000
VERSION     DAVHSY010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6207
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.070"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            25..98
                     /locus_tag="VVR43_001954"
     tRNA            25..98
                     /locus_tag="VVR43_001954"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Asn,seq:gtt)
     gene            complement(139..681)
                     /locus_tag="VVR43_001955"
     CDS             complement(139..681)
                     /locus_tag="VVR43_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEU6150260.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            788..1935
                     /locus_tag="VVR43_001956"
                     /pseudo
     CDS             788..1935
                     /locus_tag="VVR43_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(1965..4517)
                     /locus_tag="VVR43_001957"
     CDS             complement(1965..4517)
                     /locus_tag="VVR43_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU6150261.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(4579..6201)
                     /locus_tag="VVR43_001958"
     CDS             complement(4579..6201)
                     /locus_tag="VVR43_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6150262.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
BASE COUNT         2040 a         1014 c         1140 g         2013 t
ORIGIN      
        1 tcgaatcccg tacggactat tttatccgcc atagctcagt tggtagtagc gcatgactgt
       61 taatcatgat gtcgtaggtt cgagtcctac tggcggagta tagataaaag ggaacacagc
      121 tgtgttcctc tttttgtatc aatttgtatc accaagcatt ttcataagga agtctgttat
      181 ttcttgagaa ctttcttttt ttccatgtgc aatccaagtt tggcagacac caaaaagtgc
      241 atgagttaga tagatgctac tatattctaa ttcggtggta tttagattca gttgcataaa
      301 tcgcttttgt aaatctgtac taagcatgat atgaagttta tttcgtaaga aattttggat
      361 ttctttagtc ccattttcag aaagaagggc agccagaagt ggttctgact ctagatattc
      421 aaaaacttct aaaatagcgt ctcttttgtg atgagcatgt ttttgaaaaa tatattcaaa
      481 tgtatggaat agcttgcttt gatagtgctc aatcatatca tacttatcct tatagtgagt
      541 atagaagctg gaacgactaa ttccggcttt ttctactaat ttgacagtag aaattttatc
      601 aaatggctgt tccatcagta attgtaccat agcattttca atagttcgct ttgtttttaa
      661 gcgtttgtta ctttcttgca tatttcctcc ttgtaaacaa attagactat atgtctaaaa
      721 atagattttt tatcttgtaa tttagatttt ttaatgtata atctattata tcaaaatttt
      781 agacaatatg tttaaaaaag gagaaactaa gtttaaagaa tggaaagcaa ttttaaaaaa
      841 aaccaacctt tattattgtc atgatcggga tttctcttat tccagatctg tacaatatca
      901 tatttttgtc atcaatgtgg gatccatatg ggcaattgtc tgacttacct gtggcagttg
      961 taaataatga taaagaggct tcctataatg gtaatactat ggcaatagga aaagacatgg
     1021 tgtccaattt aaaagaaaat aaaaccttgg attttcattt tgtagatgaa gaggaaggaa
     1081 agaagggatt ggaagatggc gattactata tggtagtgac tttaccaagt gatttatctg
     1141 aaaaaacaac tacattatcc aatattcaat cgacagcagc ttatcaatca ttgacaagtg
     1201 agcaacaaac tgagataagt gattctgtat ctcaaaattt aactgatagt attcaatcgg
     1261 ctcagtcaat tgtagcttta gtacaagatt tacagggaag tttagaaaac ttacaaaatc
     1321 aatctaatca agtatcacct attacttcta cttctttgat aggattgtca agtggattaa
     1381 cagagataca aggagatgtt actagcaaat tagttcctgc cagtcagtcg attgcatcag
     1441 gtgtaaacgc atatactaca ggtgttgata aagtttctca ggacgtcatc cagagagccg
     1501 ttgggcttgg ttgaaatctc gagctgaaat aaatggtatt atagctgttt tggcaggaat
     1561 tttggtatat ggaggagttc atcttattgg tttaactgct aatcatgaga tgagaatatt
     1621 tattctcatc atcctaacaa gtttagtatt catgtctatg gtgaccactt taacaacgtg
     1681 gaatagccgt ataggagctt tcttctcact tattttgctt ttactacagt tagcatcaag
     1741 tgcaggtact tatccacttg ctttgacaaa tgatttcttt agatctatta atccctggtt
     1801 accaatgagc tattcagttt cgggattacg acaaacaatc tccatcaaca agtcattttc
     1861 ctagctgtca tactagctct atttactggt ttaggtatgc tagcctatca acataagaaa
     1921 atggaagaag attaaaaaaa tcgaccgatt aactggtcga ttttttatgc cttagatgac
     1981 tttcgtctgt gattatagat tccaaatagt aagagagaag taaaggaaca gattgctcca
     2041 gtaataaaac cattgggaat gaaggaaagt gtaatagttc ctttcccctt gggaatgtca
     2101 actttcataa atccagtttg agcttgttta atttctattt tcttaccatc ttggtaggca
     2161 gaccaacctt tgtcataagg aatggtgaag aaaatagatg tatcttgttg gacatcatat
     2221 gtagcaaaaa ccttgttttt agaagttgat actgtgacag gttgttcttt aattttttga
     2281 attgcctcgg tgaaagtttt ggtatctaaa cgatagaagg taggagattc aaatgatact
     2341 tgtgaatttc cagggaaact aacattgata ttgaaagttt ttttctcttt agtatatcct
     2401 agattaaaga aggagaagac attatcagtt gtaaaagtct ttttttcacc atttacaagg
     2461 atgtcaacct tcttttgttt atcgttagaa aagtgaaggt ttatgaaaga gagataaact
     2521 tggctgtttt ctggaacttc aatttgatac tggattgctg catcttcatt tgaagaactt
     2581 gtgacactaa tcaaatcatt agtattttct attttttctg ttttttcata aggtattgga
     2641 gaaaaataat caaaattgac gttagcaagt tgatttaaaa atgaggcctg attatccaag
     2701 gtatgttcat tgaacttgac atcattgtaa acagattgac tagcaactgc aatcggaaga
     2761 gagtattgat tttcatatag ggtaagatta tctttttgat agatatcttt aaaaccatac
     2821 ttatcaatag gactgtctga gatattgtac tggataccaa ataaactatc agccaaaata
     2881 ctattatttg catatcggag attgagatta gtcccagagg atttaaaacc aagtttatct
     2941 aaagtagagc ttgatgaacg atttcgaaca gatgaaaatt gagagattcc attgtagttg
     3001 aatttcatac tgtcatttcc tgtctgagtt tgtagttttt cagtacgagt aaattgattt
     3061 ccaatatatg ttgagaaaga ttccatagct gggatatctc gactataagc acttcgagaa
     3121 gcaaatcccc attccttagc aattccgtcc atttgagatg aagcatttaa actcatttca
     3181 accagtataa ataaagagat tagaatggca aatagattca cagatataaa ctttttgata
     3241 actgcaagga gtaaaagaga atagacaacc aaaaattcaa gagtaagcag aatattcaaa
     3301 tctgttaaaa aagaataatg cgattttaga tagatggtag ctaaaaatcc tgctactaca
     3361 agaaaaagcg aaactaaaaa attccagact ttaagttctt tcagacgctt taagacttct
     3421 gctgctgtgt aaattaacaa ggtagagaaa atccaagcat agcgatgtaa aaacatgttt
     3481 ggagtatgca tgccttgcca aaataagtca agagcttcta tgtaaaagct tgcaattaga
     3541 aatgcaaaga atattacata tatgagtttc acgtgaaact taatagattt cagcgtaaaa
     3601 aataaaatgg tcaaaataaa gggaagtagt ccaacaaaaa tcattgggat ggccccatac
     3661 tttgttgtgt caaaggaacc aatgaattgc ttagcaaaga gatcaagata ccagctactt
     3721 tcagtttgaa actttgtaac ttcagtcaat ttttccccat gtgtctgtaa atcaaataga
     3781 gtgggaagag tcataatcaa actagccata ccagctaaaa aggagataac tatgaaatca
     3841 agaacagatg attttcgagt cttaaagtcc cacgaaattt gacagagata ccagaaaata
     3901 agaaacaata ctgtcatata tccaaaataa taattttgaa taaataagat tgacagactt
     3961 gtaaagtaca ataggagttt cttttcagtt atcagtagat gtaaaccagt tataattaaa
     4021 ggaatcaaga taaaaacatc tagccaggtt tttatctcta attgactgac agtgaaactc
     4081 atcagagcat aggaagtaga taaggctagt tttaaagtct gagggataga ttgaaacaat
     4141 ttattcaaac taaaaaaggt tgacagacca atcaatccaa attttaagag agtggtcaga
     4201 tagacagcat ctggcatatt cgttagatca aaaaagtaaa ctagaggcgc gagaaaacta
     4261 cccaagtaat aactagatag ggcatagaag tttagcccta gaccacttgt aaaggtgtaa
     4321 aacagactac tatttccatg taggatattt cgtaaggcta catcaaaaat aacgtattga
     4381 tgaaagccat ctcctaatag aggagagttg tcgctattcc agtagatacc ttgagataga
     4441 tatactccag acataatcac tacaggaatg atgaaagaaa taaaataggt tcgatatgtt
     4501 tttaaaaatg atttcatgtt acctcgtaga atgatagaaa actcagttgg ttaacccaac
     4561 tgagttttga agttttattt agtctttcca aagttcttta acttttgctt gtacttctgc
     4621 attttctagg aattcatcgt aggtttcatc gatacggtca atgacgccat ttttagataa
     4681 gacaatgata tggttagcca aagtttgaat aaactcgtgg tcatggctgg caaagatgat
     4741 tgattcttta aagtttttca atccatcatt caagcttgag atagattcca agtccaagtg
     4801 atttgttgga tcatcaagta caaggacatt tgattttaag agcatgagtt ttgaaagcat
     4861 gacacgaact ttttctcccc ctgacaagac atttacaggt ttgttaactt catctccaga
     4921 gaagagcata cggccgagga agccacgtag gaaagtattg tcatcttctt ctttacttgc
     4981 gaattgacgc aaccagtcaa gaattgattc tcctcctgca aaatcagctg agttatcttt
     5041 tggtaggtaa gattgactag ttgtaactcc ccacttgaca gttccttcat agtcaatatc
     5101 tcccatgatt gcacgaatta atgcagtcgt ttgaatatca ttttgtccaa taagtgctgt
     5161 cttatcatct ggacgcaaga tgaaactaat attatccaag atagtttcac catcaatctt
     5221 tacagttaga ttttctactg tcaagagatc attaccaatc tcacgttccg ctttaaagtt
     5281 gataaatgga tatttacgac tagatggcac aatctcttct agctcaatct tatcaagcat
     5341 tttcttacgt gatgttgcct gccttgactt agaagcattg gcagagaaac gagcaacaaa
     5401 ttcttgcaat tgtttaattt tttcttctgc tttagcatta cggtctgcta gcaatttagc
     5461 agcaagctca gaagattcct tccagaagtc gtagtttccg acatagagtt tgatttttcc
     5521 aaagtcaagg tcggccatgt gagtacaaac tttgtttaag aagtgacggt cgtgggatac
     5581 tacgataact gtgttatcaa agtcaattaa gaagtcttct aaccaagtaa tcgattggat
     5641 atccaaaccg ttagtaggct cgtccaagag aagaacatct ggtttaccaa aaagtgcttt
     5701 ggcgaggaga acctttactt tttcaccgtt ggccaattcg ctcatgtttt ggtagtgtaa
     5761 ttcttctgga atgtttaggt tttgaagtag ttgagaggct tcactctctg cttcccaacc
     5821 tccaagttcg gcaaactctc cttcgagttc ggcagcacga accccgtcct cgtctgagaa
     5881 atcttccttc atgtagatag catctttctc tttcatgatg ctataaagtt tttcatttcc
     5941 catgataacg acatcaatgg cacgttcatc ttcgtagtca aagtgatttt gacgaagaac
     6001 agagagacgt tcatctggac caagagagat gtgaccagta gtaggttcga tatctccagc
     6061 taaaattttt aaaaaggttg attttccggc accattagca ccgattaatc cgtaagtatt
     6121 tccttctgta aatttgatat tgacatcatc aaaaagtttg cgatcactaa aacgtagtga
     6181 aacatcagat actgtaagca atatttt
//
LOCUS       DAVHSY010000070         5806 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.071, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000070 DAVHSY010000000
VERSION     DAVHSY010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5806
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.071"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            2..268
                     /locus_tag="VVR43_001959"
     CDS             2..268
                     /locus_tag="VVR43_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU6150263.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            261..629
                     /locus_tag="VVR43_001960"
     CDS             261..629
                     /locus_tag="VVR43_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU6150264.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            749..2017
                     /locus_tag="VVR43_001961"
     CDS             749..2017
                     /locus_tag="VVR43_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU6150265.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGELTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            2014..3291
                     /gene="tilS"
                     /locus_tag="VVR43_001962"
     CDS             2014..3291
                     /gene="tilS"
                     /locus_tag="VVR43_001962"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU6150266.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            3295..3837
                     /gene="hpt"
                     /locus_tag="VVR43_001963"
     CDS             3295..3837
                     /gene="hpt"
                     /locus_tag="VVR43_001963"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU6150267.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            3853..>5806
                     /gene="ftsH"
                     /locus_tag="VVR43_001964"
     CDS             3853..>5806
                     /gene="ftsH"
                     /locus_tag="VVR43_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU6150268.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
BASE COUNT         2018 a          867 c         1192 g         1729 t
ORIGIN      
        1 gatgagatta gataaatatt taaaagtatc gcgaattatc aagcgtcgta cagtcgcaaa
       61 ggaagtagca gataaaggta gaatcaaggt taatggaatc ttggccaaaa gttcaacgga
      121 cttgaaagtt aatgaccaag ttgaaattcg ctttggcaat aagttgctgc ttgtaaaagt
      181 actagagatg aaagatagta caaaaaaaga agatgcagca ggaatgtatg aaattatcag
      241 tgaaacacgg gtagaagaaa atgtctaaaa atattgtaca attgaataat tcttttattc
      301 aaaatgaata ccaacgtcgt cgctacctga tgaaagaacg acaaaaacgg aatcgtttta
      361 tgggaggggt attgattttg attatgctat tatttatctt gccaactttt aatttagcgc
      421 agagttatca gcaattactc caaagacgtc agcaattagc agacttgcaa actcagtatc
      481 aaactttgag tgatgaaaag gataaggaga cagcatttgc taccaagttg aaagatgaag
      541 attatgctgc taaatataca cgagcgaagt actattattc taagtcgagg gaaaaagttt
      601 atacgattcc tgacttgctt caaaggtgat aaaatggaaa atttattaga cgtaatagag
      661 caatttttgg gtttgtcaga tgaaaagttg gaagaattgg ctgataaaaa tcaattattg
      721 cgtttacaag aagaaaagga aaggaagaat gcgtaaattc ttaattattt tgttgctacc
      781 aagttttttg accatttcaa aagtcgttag cacagaaaaa gaagtcgtct atacttcgaa
      841 agaaatttat tacctttcac aatctgactt tggtatttat tttagagaaa aattaagttc
      901 tcccatggtt tatggagagg ttcctgttta tgcgaatgaa gatttagtag tggaatctgg
      961 ggaattgact cccaaaacaa gttttcaaat aaccgagtgg cgcttaaata aacaagggat
     1021 tccagtattt aagctatcaa atcatcaatt tatagctgcg gacaaacgat ttttatatga
     1081 tcaatcagag gtaactccaa caataaaaaa agtatggtta gaatctgact ttaaactgta
     1141 caatagtcct tatgatttaa aagaagtgaa atcatcctta tcagcttatt cgcaagtatc
     1201 aatcgacaag accatgtttg tagaaggaag agaatttcta catattgatc aggctggatg
     1261 ggtagctaaa gaatcaactt ctgaagaaga taatcggatg agtaaagttc aagaaatgtt
     1321 atctgaaaaa tatcagaaag attctttctc tatttatgtt aagcaactga ctactggaaa
     1381 agaagctggt atcaatcaag atgaaaagat gtatgcagcc agcgttttga aactctccta
     1441 tctctattat acgcaagaaa aaataaatga gggtctttat cagttagata cgactgtaaa
     1501 atacgtatct gcagtcaatg attttccagg ttcttataaa ccagagggaa gtggtagtct
     1561 tcctaaaaaa gaagataata aagaatattc tttaaaggat ttaattacga aagtatcaaa
     1621 agaatctgat aatgtagctc ataatctatt gggatattac atttcaaacc aatctgatgc
     1681 cacattcaaa tccaaaatgt ctgccattat gggagatgat tgggatccaa aagaaaaatt
     1741 gatttcttct aagatggccg ggaagtttat ggaagctatt tataatcaaa atggatttgt
     1801 gctagagtct ttgactaaaa cagattttga tagtcagcga attgccaaag gtgtttctgt
     1861 taaagtagct cataaaattg gagatgcgga tgaatttaag catgatacgg gtgttgtcta
     1921 tgcagattct ccatttattc tttctatttt cactaagaat tctgattatg atacgatttc
     1981 taagatagcc aaggatgttt atgaggttct aaaatgaggg aaccagattt tttaaatcat
     2041 tttctcaaga agggatattt caaaaagcat gctaaggcgg ttctagctct ttctggtgga
     2101 ttagattcta tgtttctatt taaggtattg tctacttatc aaaaagagtt agagattgaa
     2161 ttgattctgg ctcatgtgaa tcataagcag agaattgaat cagattggga agaaaaggaa
     2221 ttaaggaagt tggctgctga agcagagctt cctatttata tcagcaattt ttcaggagaa
     2281 ttttcagaag cgcgtgcacg aaattttcgt tatgattttt ttcaagaggt tatgaaaaag
     2341 acaggtgcga cagctttagt cactgcccac catgctgatg atcaggtgga aacgattttg
     2401 atgcgcttga ttcgaggaac tcgcttgcgc tatctatcag gaattaagga gaagcaagta
     2461 gtcggagaga tagaaatcat tcgtcccttc ttgcattttc agaaaaaaga ctttccatca
     2521 atttttcact ttgaagatac atcaaatcag gagaatcatt attttcgaaa tcgtattcga
     2581 aactcttact taccagaatt ggaaaaagaa aatcctcgat ttagggatgc aatcttaggc
     2641 attggcaatg aaattttaga ttatgatttg gcaatagctg aattatctaa caatattaat
     2701 gtggaagatt tacagcagtt attttcttac tctgagtcta cacaaagagt tttacttcaa
     2761 acttatctga atcgttttcc agatttgaat cttacaaaag ctcagtttgc tgaagttcag
     2821 cagattttaa aatctaaaag ccagtatcgt catccgatta aaaatggcta tgaattgata
     2881 aaagagtacc aacagtttca gatttgtaaa atcagtccgc aggctgatga aaaggaagat
     2941 gaacttgtgt tacactatca aaatcaggta gcttatcaag gatatttatt ttcctttgga
     3001 cttccattag aaggtgaatc aattcaacaa atacctgttt cacgtgaaac atccatacac
     3061 attcgtcatc gaaaaacagg agatgttttg attcaaaatg ggcatagaaa aaaactcaga
     3121 cgtttattta ttgatttgaa aatccctatg gaaaagagaa actctgctct tattattgag
     3181 caatttggtg aaattgtctc aattttggga attgcgacca ataatttgag taaaaaaacg
     3241 aaaaatgata taatgaacac tgtactttat atagaaaaaa tagataggta aaaaatgtta
     3301 gaaaacgata ttaaaaaagt cctcgtttca cacgatgaaa ttacagaagc agctaaaaaa
     3361 ctaggtgctc aattaactaa agattatgca ggaaaaaatc caatcttagt tgggatttta
     3421 aaaggatcta ttccttttat ggctgaattg gtcaaacata ttgatacaca tattgaaatg
     3481 gacttcatga tggtttctag ctaccatggt ggaacagcaa gtagtggtgt tatcaatatt
     3541 aaacaagatg tgactcaaga tatcaaagga agacatgttc tatttgtaga agatatcatt
     3601 gatacaggtc aaactttgaa gaatttgcga gatatgttta aagcaagaga agcagcttct
     3661 gttaaaattg caaccttgtt ggataaacca gaaggacgtg ttgtagaaat tgaggcagac
     3721 tatacctgct ttactatccc aaatgagttt gtagtaggtt atggtttaga ctacaaagaa
     3781 aattatcgta atcttcctta tattggagta ttgaaagagg aagtgtattc aaattagaaa
     3841 gaataatctt taatgaaaaa acaaaataat ggtttaatta aaaatccttt tctatggtta
     3901 ttatttatct ttttccttgt gacaggattc cagtatttct attctgggaa taactcagga
     3961 ggaagtcagc aaatcaacta tactgagttg gtacaagaaa ttaccgatgg taatgtaaaa
     4021 gaattaactt accaaccaaa tggtagtgtt atcgaagttt ctggtgtcta taaaaatcct
     4081 aaaacaagta aagaaggaac aggtattcag tttttcacgc catctgttac taaggtagag
     4141 aaatttacca gcactattct tcctgcagat actaccgtat cagaattgca aaaacttgct
     4201 actgaccata aagcagaagt aactgttaag catgaaagtt caagtggtat atggattaat
     4261 ctactcgtat ccattgtgcc atttggaatt ctattcttct tcctattctc tatgatggga
     4321 aatatgggag gaggcaatgg ccgtaatcca atgagttttg gacgtagtaa ggctaaagca
     4381 gcaaataaag aagatattaa agtaagattt tcagatgttg ctggagctga ggaagaaaaa
     4441 caagaactag ttgaagttgt tgagttctta aaagatccaa aacgattcac aaaacttgga
     4501 gcccgtattc cagcaggtgt tcttttggag ggacctccgg ggacaggtaa gactttgctt
     4561 gctaaggcag tcgctggaga agcaggtgtt ccattcttta gtatctcagg ttctgacttt
     4621 gtagaaatgt ttgtcggagt tggagctagt cgtgttcgct ctctttttga ggatgccaaa
     4681 aaagcagcac cagctatcat ctttatcgat gaaattgatg ctgttggacg tcaacgtgga
     4741 gtcggtctcg gcggaggtaa tgacgaacgt gaacaaacct tgaaccaact tttgattgag
     4801 atggatggtt ttgagggaaa tgaagggatt atcgtcatcg ctgcgacaaa ccgttcagat
     4861 gtacttgatc ctgccctttt gcgtccagga cgttttgata gaaaagtatt ggttggccgt
     4921 cctgatgtta aaggtcgtga agcaatcttg aaagttcacg ctaagaacaa gcctttagca
     4981 gaagatgttg atttgaaatt agtggctcaa caaactccag gctttgttgg tgctgattta
     5041 gagaatgtct tgaatgaagc agctttagtt gctgctcgtc gcaataaatc gataattgat
     5101 gcttcagata ttgatgaagc agaagataga gttattgctg gaccttctaa gaaagataag
     5161 acagtttcac aaaaagaacg agaattggtt gcttaccatg aggcaggaca taccattgtt
     5221 ggtctagtct tgtcgaatgc tcgcgttgtc cataaggtta caattgtacc acgcggccgt
     5281 gcaggcggat acatgattgc acttcctaaa gaggatcaaa tgcttctatc taaagaagat
     5341 atgaaagagc aattggctgg cttaatgggt ggacgtgtag ctgaagaaat tatctttaat
     5401 gtccaaacta caggagcttc aaacgacttt gaacaagcga cacaaatggc acgtgcaatg
     5461 gttacagagt acggtatgag tgaaaaactt ggcccagtac aatatgaagg aaaccatgct
     5521 atgcttggtg cacagagtcc tcaaaaatca atttcagaac aaacagctta tgaaattgat
     5581 gaagaggttc gttcattatt aaatgaggca cgaaataaag ctgctgaaat tattcagtca
     5641 aatcgtgaaa ctcacaagtt aattgcagaa gcattattga aatacgaaac attggatagt
     5701 acacaaatta aagctcttta cgaaacagga aagatgcctg aagcagtaga agaggaatct
     5761 catgcactat cctatgatga agtaaagtca aaaatgaatg acgaaa
//
LOCUS       DAVHSY010000071         5419 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.073, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000071 DAVHSY010000000
VERSION     DAVHSY010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5419
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.073"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(1..668)
                     /locus_tag="VVR43_001965"
                     /pseudo
     CDS             complement(1..668)
                     /locus_tag="VVR43_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(771..995)
                     /locus_tag="VVR43_001966"
                     /pseudo
     CDS             complement(771..995)
                     /locus_tag="VVR43_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1336..2682
                     /gene="gdhA"
                     /locus_tag="VVR43_001967"
     CDS             1336..2682
                     /gene="gdhA"
                     /locus_tag="VVR43_001967"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU6150269.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFNPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGVV"
     gene            complement(2971..>5419)
                     /locus_tag="VVR43_001968"
     CDS             complement(2971..>5419)
                     /locus_tag="VVR43_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6150270.1"
                     /translation="LNKNNIIYAEQKTLFILSYLKKIRLESLEENQEFNKLLKITDIT
                     NTDFKSAVEKLHERELCNIYNDKIVKIADQSLDDYIVIKFLINKKISILEILHELYPV
                     NDQRVVQILNQCSNFIRKESDLEGVSDAVKSYYYNESNFESDELKEKFLIQFGVLLPL
                     EAISHVKNKIDNIESQVYTKTNFINQKDKKGSIEDSVLNIVFVTTRTKYCSQILQLLL
                     KYFDKNPNKISEVYSILEANYGLVTEREYIDYTLAENTISELANLDLTKSYNQELIVT
                     ILKQFLKIEIERTEAHEEKFTFGRYKVPDSEKLKQYHRSILKLLANLYNIGSCETRFY
                     IEKMLYDYRRKILTYSESHRNIIFGDLRNIRKLFFNDIKNLSMIGEKIVYALHKAEVK
                     ENLPIVFDDYIISDRQKIYNNLTNPNHAWFYDASEIKLQQIANSYSNVWLKIFNFANQ
                     FKHSLFMNDNNIELVLFNMFLLSKNDKKIKFLNYMFKSNYHFVNMNPISFLENIEESS
                     MQSVIVSSPESEKYEWQLAYLTQLENVKNEDLQTLKSILEANSLPCYFTILNFERLIL
                     KDPSLKELLIQKAGNTNFVISDFIREEEVPKLINLIGVKELKFWYLINLENCQNHSYN
                     LFQKLGEKDVDFSVEVLKKIDELRIGHSNLGYMVLHSISEFRDKKEIYKKFIRFAINR
                     PYYYYNNMIDDIIKNDSQIILEILEETNNEQSAIRLVNLGVEFLENNNQKLILFNLLR
                     AKGFGKKSFQEIHFTPYSHFYTGSHVPVLELEKELLERIKKIFETGIDYINLLLYLNK
                     LIDCKRKAIERELEKEF"
BASE COUNT         1741 a          934 c          801 g         1943 t
ORIGIN      
        1 ctttaaggta cttgatttat gccatatagc attgtccata acgagtaaaa gataatcatc
       61 tggataagct tgtgaaagct cttctaaaaa ggcgttcatc cactcagtat tacatccacc
      121 agctcttaag aaaaatgatt cgcctgtatg ggcatcaaca gctccataac aatagtgaaa
      181 ttctcgtata tagtgactat ggacatgtgg acctactcct attggagccc aacaagatcc
      241 cagtttactg attctaccga aaccagcctc atcttggtac atcaagcgaa ccttatgaaa
      301 aggtctactg gttttaaaac gctttctttt cttcttgaat tgagatttta tttttagacg
      361 cgacaatggt ttgagcgtct gctttcctag gatgttctgg acgtggcata atatttcgcc
      421 aaccatggcg cttcaacagt tgatagaagg catcacgtgt gtaggaacga tataagcctg
      481 aaataaggta ttgtaacaaa ttctcctgcc tctgtagcct tcaaatggcg ggcaagaaag
      541 actttctctt cctcaactgt catatatgca tggttacgac caccacgtgt ttcttgaagg
      601 agagagtcga gtccgaactc ctcatatttt tttacatttc gccaaatcgt tgtttgatta
      661 cagtctatag tgtattgaat ctataacagt acaccttggc tgctaaaata tttctataaa
      721 tcaatttgac tttcctgata gagttgttca catcttattt caaaccacta taaaagttct
      781 ataatctctt tataaaattt gcccatcaga cgaaatataa tagattgaaa ctagaatagt
      841 acacctctac ttctaaaaca ttgttagaaa tcgatttgtc ctgttcttgt ttcattttac
      901 tatagaacga tttgaaggcg tttataatat ttagctgtac gagagtcttt taaaagtgtt
      961 tttatggttt ggatttcttc tttagttgat ttcatattac tattatataa tgctttttga
     1021 ttttagtctg gtataaatat tgctttcctc caaaatggtc atagttttac tggcaaatct
     1081 aacatatcac ggataaatta acaagtgatt tctgaattac taaacatttt cttttcttat
     1141 agcataccat actttaagat tttgtcttta agaaagatat ttccaagaaa aacgttcgtt
     1201 tttttatcta ttttcaaaaa aaccaaaaac tgaattgaaa gaatttttag aaaatttctg
     1261 ttttttcttt acagtgaaaa aaaattctgc tataatgtct tatgtaataa aatatgacaa
     1321 taaaaggaga acgatatgac atctgctaaa gaatatatcc aaagcgtgtt tgaaactgtg
     1381 aaagctcgta acgggcacga ggctgaattc ctccaagctg ttgaagaatt tttcaacact
     1441 ttagaacctg tatttgaaaa acaccctgag tatatcgaag aaaatatctt ggcacgtatt
     1501 actgagcctg agcgcgtggt ttctttccgt gttccttggg ttgaccgtga tggaaaaatt
     1561 caagtaaacc gtggttaccg tgttcaattc aactcagctg ttggaccata caaaggtgga
     1621 cttcgtttcc acccaactgt aaaccaaggg atcttgaaat tcctcggatt tgaacaaatc
     1681 tttaaaaatg tcttgactgg acttcctatc ggtggaggta aaggtggatc agacttcaat
     1741 cctaaaggta aaacagatgc tgaagtgatg cgcttctgcc aaagcttcat gactgaattg
     1801 caaaaacaca tcggaccatc acttgacgta cctgctggtg atatcggtgt tggtggacgt
     1861 gagattggtt acctttacgg tcaatacaaa cgtcttaacc aatttgatgc tggtgtcttg
     1921 actggtaaac ctcttggatt tggtggtagc ttgattcgtc cagaagcaac tggttacggt
     1981 ttggtttact atactgaaga aatgctcaaa gctaacggta acagctttgc tggtaagaaa
     2041 gtcgttattt caggttctgg taacgttgct caatatgctc ttcaaaaagc aactgaactc
     2101 ggtgcaactg ttatttctgt ttctgactca aatggttatg tcatcgatga aaatggtatc
     2161 gacttcgatc ttttggttga tgttaaagaa aaacgtcgtg ctcgtttgac tgagtatgca
     2221 gctgaaaaag caactgcaac ctaccacgaa ggtactgtat ggacttacgc tggaaactat
     2281 gacattgctc ttccatgtgc cactcaaaac gaaatcaacg gtgaagcagc taaacgtttg
     2341 gttgctcaag gcgttatctg tgtatctgaa ggtgccaaca tgccaagcga ccttgatgcc
     2401 atcaaagttt acaaagaaaa tggtatcttc tacggacctg caaaagctgc caacgctggt
     2461 ggtgtagccg tttcagccct tgaaatgagc caaaacagcc ttcgcctctc atggactcgt
     2521 gaagaagttg atggacgtct caaagacatc atgaccaaca tctttaacac agctaaaaca
     2581 acttcagaaa catatggtct tgataaagac taccttgcag gagctaacat tgctgccttt
     2641 gaaaatgtag caaacgctat gattgcccaa ggcgtggtat aaaaaaaaat tacggaaact
     2701 gactacccag acgggtagcc agttttttca attcctaaaa tttaagattc taataccctt
     2761 tatgcaaaaa tatagaattc tacctttttc tttatatagg ctaatgtttt taatatattt
     2821 attgtctatt tttgaaaaga caataaaact attctactat agattatcat ttcccacaat
     2881 tcataactca aacctaatat tttgttataa aacagtagat tttatttatt atatctggca
     2941 ccttaaaaag taagaaatat aaattaaaat ttaaaactct ttttccaatt ctctttcaat
     3001 agcttttcgc ttgcaatcaa ttagtttatt caagtacagt agcaagttaa tgtagtctat
     3061 acccgtttca aatatctttt taattctttc taggagttct ttttctaatt ccaacaccgg
     3121 aacatgacta ccagtataaa aatgtgaata gggagtaaaa tgtatttctt ggaatgactt
     3181 cttaccaaat cctttagctc tgagaagatt aaatagtatt agtttttgat tgttgttttc
     3241 taaaaattct acacctagat tgaccaatct aattgcagat tgctcattat ttgtttcctc
     3301 cagtatttct aatatgatct gactgtcatt ttttataata tcatcaatca tattattgta
     3361 gtagtaatat ggcctattta ttgcaaaacg gataaacttt ttataaattt ctttcttatc
     3421 tctaaattca cttatagaat gtaataccat gtatcctaaa ttggaatgac ctattctcaa
     3481 ttcatcaatt ttcttcaata cttctaccga aaaatcaaca tctttttcac ctaatttttg
     3541 aaaaagatta tagctgtgat tctgacaatt ttctaaattt attaaatacc aaaacttcaa
     3601 ctcttttact ccaattagat ttattaattt tggcacctct tcttctctta taaaatcaga
     3661 aataacaaaa tttgtattcc cagctttttg tattaacaac tcttttaaac taggatcttt
     3721 caaaatcaat ctctcaaaat ttaaaattgt aaaataacat ggtaaagaat tagcttctag
     3781 aatactcttt aatgtttgta gatcttcatt tttaacgttt tcaagttgtg ttaaataagc
     3841 aagttgccat tcatattttt ctgattctgg agaggaaaca ataacagact gcattgaact
     3901 ttcctcaata ttttctaaaa aactaatcgg attcatattt acaaaatgat agtttgattt
     3961 aaacatataa tttagaaatt taatcttttt atcatttttt gatagtaaaa acatattgaa
     4021 tagtactagc tcaatgttat tgtcattcat aaataagcta tgtttgaatt gatttgcaaa
     4081 attaaaaatt ttaagccaaa catttgaata gctatttgca atttgttgta gtttaatttc
     4141 agaagcatca taaaaccaag catggttagg atttgttaaa ttattatata ttttttgtct
     4201 gtcagaaatt atataatcat caaaaacaat cggtaaattt tctttcactt cggctttatg
     4261 caaagcataa actatttttt ctccaatcat agataagttt ttaatgtcat taaaaaataa
     4321 tttcctaata tttctcaaat ctccaaagat aatattacga tgactttctg aataggtcaa
     4381 aatttttctt ctgtaatcat atagcatttt ctcaatataa aatctagttt cacaactccc
     4441 tatattatac aaattcgcta aaagttttag tatacttcta tgatactgtt ttaatttttc
     4501 actatccggg actttatagc gcccaaaagt aaatttctct tcatgagcct ctgttctttc
     4561 gatttcaatt ttaagaaact gcttcaaaat tgtcacgatt aattcttggt tataactttt
     4621 cgtcaaatca agattagcaa gttcagaaat ggtattttca gctaaggtat aatcaatata
     4681 ttctctttct gtaaccaacc cgtagtttgc ttcaagaata ctataaacct cagaaatttt
     4741 attaggattt ttatcaaagt actttaacaa taattggaga atttgactac aatattttgt
     4801 ccgtgtagtt acaaatacaa tatttaaaac tgaatcctca atagatccct ttttatcctt
     4861 ctgattaata aaattagtct ttgtataaac ctgagactct atattatcaa ttttattttt
     4921 aacgtgtgaa attgcttcta aaggaagtaa tactccaaat tgtattaaaa acttttcttt
     4981 aagttcatca ctttcaaaat tactttcatt gtaataatat gatttaactg catcagaaac
     5041 gccttctaaa tcactctctt tcctaataaa attggaacat tgatttagta tttgaacaac
     5101 tctttggtcg tttactggat ataactcatg taaaatttct aaaattgata ttttcttgtt
     5161 aattaaaaac ttgataacta tataatcatc taatgattga tctgctatct ttacaatttt
     5221 gtcgttataa atattacaca actctctttc atgaagcttc tccactgcac tcttaaagtc
     5281 agtatttgtt atgtcagtta tttttagtaa tttattgaat tcctggttct cttctaaact
     5341 ttccagtcta atctttttta agtaagataa aataaataga gtcttttgtt ctgcataaat
     5401 aatgttgttt ttatttaaa
//
LOCUS       DAVHSY010000072         5012 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.074, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000072 DAVHSY010000000
VERSION     DAVHSY010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5012
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.074"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            145..1690
                     /locus_tag="VVR43_001969"
     rRNA            145..1690
                     /locus_tag="VVR43_001969"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1742..1814
                     /locus_tag="VVR43_001970"
     tRNA            1742..1814
                     /locus_tag="VVR43_001970"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1775..1777,aa:Ala,seq:tgc)
     gene            1939..4840
                     /locus_tag="VVR43_001971"
     rRNA            1939..4840
                     /locus_tag="VVR43_001971"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4917..>5012
                     /gene="rrf"
                     /locus_tag="VVR43_001972"
     rRNA            4917..>5012
                     /gene="rrf"
                     /locus_tag="VVR43_001972"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1409 a         1022 c         1477 g         1104 t
ORIGIN      
        1 tcgcttgaga gaagcaagtg acaaagacct ttgaaaactg aacaagacga accaatgtgc
       61 agggcgctac aacataagtt gtagtactga acaatgaaaa aacaataaat ctgtcagtga
      121 cagaaatgag tgagaactca aacttttaat gagagtttga tcctggctca ggacgaacgc
      181 tggcggcgtg cctaatacat gcaagtagaa cgctgaagga ggagcttgct tctctggatg
      241 agttgcgaac gggtgagtaa cgcgtaggta acctgcctgg tagcggggga taactattgg
      301 aaacgatagc taataccgca taagagtgga tgttgcatga catttgctta aaaggtgcac
      361 ttgcatcact accagatgga cctgcgttgt attagctagt tggtggggta agggctcacc
      421 aaggcgacga tacatagccg acctgagagg gtgatcggcc acactgggac tgagacacgg
      481 cccagactcc tacgggaggc agcagtaggg aatcttcggc aatggacgga agtctgaccg
      541 agcaacgccg cgtgagtgaa gaaggttttc ggatcgtaaa gctctgttgt aagagaagaa
      601 cgagtgtgag agtggaaagt tcacactgtg acggtatctt accagaaagg gacggctaac
      661 tacgtgccag cagccgcggt aatacgtagg tcccgagcgt tgtccggatt tattgggcgt
      721 aaagcgagcg caggcggtta gataagtctg aagttaaagg ctgtggctta accatagtag
      781 gctttggaaa ctgtttaact tgagtgcaag aggggagagt ggaattccat gtgtagcggt
      841 gaaatgcgta gatatatgga ggaacaccgg tggcgaaagc ggctctctgg cttgtaactg
      901 acgctgaggc tcgaaagcgt ggggagcaaa caggattaga taccctggta gtccacgctg
      961 taaacgatga gtgctaggtg ttagaccctt tccggggttt agtgccgtag ctaacgcatt
     1021 aagcactccg cctggggagt acgaccgcaa ggttgaaact caaaggaatt gacgggggcc
     1081 cgcacaagcg gtggagcatg tggtttaatt cgaagcaacg cgaagaacct taccaggtct
     1141 tgacatccct ctgaccgctc tagagataga gttttccttc gggacagagg tgacaggtgg
     1201 tgcatggttg tcgtcagctc gtgtcgtgag atgttgggtt aagtcccgca acgagcgcaa
     1261 cccctattgt tagttgccat catttagttg ggcactctag cgagactgcc ggtaataaac
     1321 cggaggaagg tggggatgac gtcaaatcat catgcccctt atgacctggg ctacacacgt
     1381 gctacaatgg ctggtacaac gagtcgcaag ccggtgacgg caagctaatc tcttaaagcc
     1441 agtctcagtt cggattgtag gctgcaactc gcctacatga agtcggaatc gctagtaatc
     1501 gcggatcagc acgccgcggt gaatacgttc ccgggccttg tacacaccgc ccgtcacacc
     1561 acgagagttt gtaacacccg aagtcggtga ggtaaccgta aggagccagc cgcctaaggt
     1621 gggatagatg attggggtga agtcgtaaca aggtagccgt atcggaaggt gcggctggat
     1681 cacctccttt ctaaggataa ggaactgcgc attggtcttg tttagtcttg agaggtcttg
     1741 tggggcctta gctcagctgg gagagcgcct gctttgcacg caggaggtca gcggttcgat
     1801 cccgctaggc tccattggtg agagatcacc aagtaatgca cattgaaaat tgaatatcta
     1861 tatcaaatag taacaagaaa ataaaccgaa aacgctgtag tattaataag agtttatgac
     1921 tgaaaggtca gaaaataagg ttaagttaat aagggcgcac ggtggatgcc ttggcactag
     1981 gagccgacga aggacgtgac aaacgacgat ataccttggg tagctgtaag taagcgatga
     2041 tccagggatt tccgaatggg ggaacccaac aggtaatacc tgttacccac atctgttaag
     2101 gatgtgagga ggaagacgca gtgaactgaa acatctaagt agctgcagga agagaaagca
     2161 aaagcgattg ccttagtagc ggcgagcgaa acggcagaag ggcaaaccga agagtttact
     2221 cttcggggtt gtaggactgc aatgtggact caaagattat agaagaatga tttgggaaga
     2281 tcagccaaag agagtaatag cctcgtattt aaaatagtct ttgtacctag cagtatcctg
     2341 agtacggcgg gacacgtgaa atcccgtcgg aatctgggag gaccatctcc caaccctaaa
     2401 tactccctag tgaccgatag tgaaccagta ccgtgaggga aaggtgaaaa gcaccccggg
     2461 aggggagtga aatagaacct gaaaccgtgt gcctacaaca agttcgagcc cgttaatggg
     2521 tgagagcgtg ccttttgtag aatgaaccgg cgagttacgt tatgatgcga ggttaagttg
     2581 aagagacgga gccgtaggga aaccgagtct gaacagggcg aattagtatc atgacgtaga
     2641 cccgaaacca tgtgacctac ccatgagcag gttgaaggtg cggtaagacg cactggagga
     2701 ccgaaccagg gcacgttgaa aagtgcttgg atgacttgtg ggtagcggag aaattccaaa
     2761 cgaacttgga gatagctggt tctctccgaa atagctttag ggctagcgtc gacattagag
     2821 attcttggag gtagagcact gtttgggtga ggggtccatc ccggattacc aatctcagat
     2881 aaactccgaa tgccaatgaa ttatggtcgg cagtcagact gcgagtgcta agatccgtag
     2941 tcgaaaggga aacagcccag accaccagct aaggtcccaa aataattgtt aagtggaaaa
     3001 ggatgtgggg ttgcacagac aactaggatg ttagcttaga agcagctatt cattcaaaga
     3061 gtgcgtaata gctcactagt cgagtgaccc tgcgccgaaa atgtaccggg gctaaaacaa
     3121 tttaccgaag ctgtggatac ctttataggt atggtaggag agcgttctat gtgtgatgaa
     3181 ggtataccgt gaggagtgct ggaacgcata gaagtgagaa tgccggtatg agtagcgaaa
     3241 gacaggtgag aatcctgtcc accgtaagac taaggtttcc aggggaaggc tcgtccgccc
     3301 tgggttagtc gggacctaag gagagaccga aaggtgtatc cgatggacaa caggttgata
     3361 ttcctgtact agagtatgta gtgatggagg gacgcagtag gctaactaaa gcagacgatt
     3421 ggaagagtct gtctaagcag tgaggtgtga attgagtcaa atgcttaatt ctataacatt
     3481 gagctgtgat ggggagcgaa gtttagtagc gaagttagtg acgtcacact gccaagaaaa
     3541 gcttctagcg tttaaacata ctctacccgt accgcaaacc gacacaggta gtcgaggcga
     3601 gtagcctcag gtgagcgaga gaactctcgt taaggaactc ggcaaaatga ccccgtaact
     3661 tcgggagaag gggtgctgac tttaggtcag ccgcagtgaa taggcccaag caactgttta
     3721 tcaaaaacac agctctctgc taaatcgtaa gatgatgtat agggggtgac gcctgcccgg
     3781 tgctggaagg ttaagaggag tgcttagcgt aagcgaaggt atgaattgaa gccccagtaa
     3841 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
     3901 cccgcacgaa aggcgtaatg atttgggcac tgtctcaacg agagactcgg tgaaatttta
     3961 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
     4021 cagtttgata ttgagtgtct gtaccacatg tacaggatag gtaggagtct aagagatcgg
     4081 gacgccagtt tcgaaggaga cgctgttggg atactaccct tgtgttatgg ccactctaac
     4141 ccagataggt gatccctatc ggagacagtg tctgacgggc agtttgactg gggcggtcgc
     4201 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgca
     4261 gagtgtaaag gtataaggga gcttgactgc gagagctaca actcgagcag ggacgaaagt
     4321 cgggcttagt gatccggtgg ttccgtatgg aagggccatc gctcaacgga taaaagctac
     4381 cctggggata acaggcttat ctcccccaag agttcacatc gacggggagg tttggcacct
     4441 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     4501 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     4561 gcgggcgtag gaaatttgag aggatctgct cctagtacga gaggaccaga gtggacttac
     4621 cgctggtgta ccagttgtct tgccaaaggc atcgctgggt agctatgtag ggaagggata
     4681 aacgctgaaa gcatctaagt gtgaaaccca cctcaagatg agatttccca tgattatata
     4741 tcagtaagag ccctgagaga tgatcaggta gataggttag aagtggaagt gtggcgacac
     4801 atgtagcgga ctaatactaa tagctcgagg acttatccaa agtaactgag aatatgaaag
     4861 cgaacggttt tcttgaattg aatagatatt caattttgag taggtattac tcagagttaa
     4921 gtgacgatag cctaggagat acacctgtac ccatgccgaa cacagaagtt aagccctaga
     4981 acgccggaag tagttggggg ttgccccctg tg
//
LOCUS       DAVHSY010000073         4796 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.075, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000073 DAVHSY010000000
VERSION     DAVHSY010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4796
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.075"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(62..187)
                     /gene="comC"
                     /locus_tag="VVR43_001973"
     CDS             complement(62..187)
                     /gene="comC"
                     /locus_tag="VVR43_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU6150271.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            complement(352..425)
                     /locus_tag="VVR43_001974"
     tRNA            complement(352..425)
                     /locus_tag="VVR43_001974"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(389..391),aa:Arg,seq:tct)
     gene            complement(469..948)
                     /gene="rlmH"
                     /locus_tag="VVR43_001975"
     CDS             complement(469..948)
                     /gene="rlmH"
                     /locus_tag="VVR43_001975"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU6150272.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            1131..2312
                     /locus_tag="VVR43_001976"
     CDS             1131..2312
                     /locus_tag="VVR43_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEU6150273.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            2370..3128
                     /locus_tag="VVR43_001977"
     CDS             2370..3128
                     /locus_tag="VVR43_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU6150274.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEACAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            3341..4702
                     /gene="dnaA"
                     /locus_tag="VVR43_001978"
     CDS             3341..4702
                     /gene="dnaA"
                     /locus_tag="VVR43_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU6150275.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
BASE COUNT         1679 a          857 c          794 g         1466 t
ORIGIN      
        1 aaaaaatgaa caataaccgt cccaaatcca aataaatcca ttactctttc cccttatttc
       61 attacttttt tctttgtaaa ataaaatcac ggaagaattt tgacaatctc atctccccac
      121 ctttaatctt ttgtaagtct ttttccttca aagctacaaa ctgttccaat ttaactgtgt
      181 ttttcataat aaaatctcct aaaatgtttt ttcttgtaag ctaacttaca aaaaccatta
      241 tacaaaatgg aatttcgttt tagataaaat tctctcaact gtcatttttt tctcccaaag
      301 tgtacttttt taagaaaaaa gccgggaaaa ttcccagctt tgctattata ttgatcccag
      361 caggattcga acctgcgacc gttcgcttag aaggcgaatg ctctatccag ctgagctatg
      421 agacctaaca caattattct accaaaaatt caattaaaag tcaattttct atttatggta
      481 ggggaatccc tgctgaatcg taaaagcgcg atagatttgt tcaacaagaa ctagtctcat
      541 taactgatga ggcaaggtta ggcgaccaaa actgacagaa agattggctc tattttttac
      601 agatgatgac aatcctaaac ttcccccaat aataaaagta agagtagaaa atccttttat
      661 agaagtttct tctaactgct tactaaattc ttctgagaag aaagttttcc cttcaatggc
      721 taacacaata acgaaatcac ggtcagcaat ttttgataaa attctctgac cttctatttc
      781 taaaatcttt tgattttctg attcactggc cttatctggt gttttttcat ctgataactc
      841 aatcatttca aacttagcaa atctagaaat tcgttttgaa tactctgcga taccatcttt
      901 taaatacttt tctttcagtt tcccaactgt tacaacttta attttcatga ctctattcta
      961 acatattctc tattttttca catcttattc acaaaataaa aaatagattt caattaagaa
     1021 aatcacagtt tcaaaagagt tatccacagt ttgtgtaaaa cttttgtgtt taagttataa
     1081 ttaagctagt cagtttatac tttcagtaat tcaaacatat ggaggcaaat atgaaacatc
     1141 taaaaacatt ttacaaaaaa tggtttcaat tattagtcgt tatcgtcatt agctttttta
     1201 gtggagcctt gggtagtttt tcaataactc aactaactca aaaaagtagt gtaaacaact
     1261 ctaacaacaa tagtactatt acacaaactg cctataagaa cgaaaattca acaacacagg
     1321 ctgttaacaa agtaaaagat gctgttgttt ctgttattac ttattcggca aacagacaaa
     1381 atagcgtatt tggcaatgat gatactgaca cagattctca gcgaatctct agtgaaggat
     1441 ctggagttat ttataaaaag aatgataaag aagcttacat cgtcaccaac aatcacgtta
     1501 taaatggcgc cagcaaagta gatattcgat tgtcagatgg gactaaagta cctggagaaa
     1561 ttgtcggagc tgacactttc tctgatattg ctgtcgtcaa aatctcttca gaaaaagtga
     1621 caacagtagc tgagtttggt gattctagta agttaactgt aggagaaact gctattgcca
     1681 tcggtagccc gttaggttct gaatatgcaa atactgtcac tcaaggtatc gtatccagtc
     1741 tcaatagaaa tgtatcctta aaatcggaag atggacaagc tatttctaca aaagccatcc
     1801 aaactgatac tgctattaac ccaggtaact ctggcggccc actgatcaat attcaagggc
     1861 aggttatcgg aattacctca agtaaaattg ctacaaatgg aggaacatct gtagaaggtc
     1921 ttggtttcgc aattcctgca aatgatgcta tcaatattat tgaacagtta gaaaaaaacg
     1981 gaaaagtgac gcgtccagct ttgggaatcc agatggttaa tttatctaat gtgagtacaa
     2041 gcgacatcag aagactcaat attccaagta atgttacatc tggtgtaatt gttcgttcgg
     2101 tacaaagtaa tatgcctgcc aatggtcacc ttgaaaaata cgatgtaatt acaaaagtag
     2161 atgacaaaga gattgcttca tcaacagact tacaaagtgc tctttacaac cattctatcg
     2221 gagacaccat taagataacc tactatcgta acgggaaaga agaaactacc tctatcaaac
     2281 ttaacaagag ttcaggtgat ttagaatctt aattgacatc tatgtaaaga aagctttaca
     2341 taagagaaaa gatgtgttag tgtagaatca tggaaaaatt tgaaatgatt tctatcacag
     2401 atatacaaaa aaatccctat caaccccgaa aagaatttga tagagaaaaa ctagatgaac
     2461 tagcacagtc tatcaaagaa aatggggtca ttcaaccgat tattgttcgt caatctcctg
     2521 ttattggtta tgaaatcctt gcaggagaga gacgctatcg ggcttcactt ttagctggtc
     2581 tacggtctat cccagctgtt gttaaacaga tttcagacca agagatgatg gtccagtcca
     2641 ttattgaaaa tttacagaga gaaaatttaa acccaataga agaagcatgc gcctatgaat
     2701 ctctcgtaga gaaaggattc acccatgctg aaattgcaga taaaatgggc aagtctcgtc
     2761 catatatcag caactccatt cgtttacttt ccttgccaga acagattctc tcagaagtag
     2821 aaaatggcaa actatcacaa gcccatgcgc gttccctagt tgggttaaat aaggaacaac
     2881 aagactattt ctttcaacgg attatagaag aagatatttc tgtaaggaag ttagaaactc
     2941 ttctgacaga gaaaaaacaa aagaaacagc aaaaaactaa tcatttcata caaaatgaag
     3001 aaaaacagtt aagaaaacta ctcggattag atgtagaaat taaactatct aaaaaagaca
     3061 gtggaaaaat cattatttct ttttcaaatc aagaagaata tagtagaatt atcaacagcc
     3121 tgaaataagg ctgttctttt atttttttat ctcacaaggt tatccactat gtttttcgat
     3181 aaaaagctta ataaatcaat aatttcttct tttatcccca acctgtggat aaagtttggt
     3241 aacattgtgg attatttttc acagcttgtg gaaaattctt gctatctatg gtaaaatatc
     3301 tctagtatta aacttttaaa tagtaaagga ggagaaagga ttgaaagaaa aacaattttg
     3361 gaatcgtata ttagaatttg cacaagaaag actgactcga tccatgtatg atttctatgc
     3421 tattcaagct gaactcatca aggtagagga aaatgttgcc actatatttc tacctcgctc
     3481 tgaaatggaa atggtctggg aaaaacaact aaaagatatt attgtagtag ctggttttga
     3541 aatttatgac gctgaaataa ctccccacta tattttcacc aaacctcaag atacgactag
     3601 ctcacaagtt gaagaagcta caaatttaac tctttatgac tatagtccaa agttagtatc
     3661 tattccttat tcagatacgg gattaaaaga aaagtatacc tttgataact ttattcaagg
     3721 ggatggaaat gtttgggctg tatcagccgc tttagctgtc tctgaagatt tggctctgac
     3781 ctataaccct ctttttatct atggaggacc aggccttggt aagactcact tattaaacgc
     3841 tattggaaat gaaattctaa aaaatattcc taatgcgcgt gttaaatata tccctgccga
     3901 aagctttatt aatgactttc ttgatcacct aagacttggg gaaatggaaa agtttaaaaa
     3961 gacctatcgt agtcttgatc ttttgttaat cgatgatata cagtcactca gcggaaaaaa
     4021 agtcgcaact caggaagaat ttttcaatac ctttaacgcc cttcatgaca agcaaaaaca
     4081 gattgtccta acgagtgatc gtagtccaaa acatctagaa gggctcgagg agaggcttgt
     4141 cacgcgtttt agttggggat tgacacaaac tatcacaccc cctgactttg aaacacgtat
     4201 tgccatttta caaagtaaga cggaacattt aggctacaat ttccaaagtg atactctaga
     4261 atacctagct gggcaatttg attcaaatgt tcgagatctt gagggagcca tcaacgacat
     4321 cactttaatt gccagagtaa aaaaaatcaa ggatatcact attgatattg ctgcagaagc
     4381 cattagagcc cgcaaacaag atgttagcca aatgctcgtc atcccaattg ataaaatcca
     4441 aactgaagtt ggtaactttt atggtgttag tatcaaagaa atgaagggaa gtagacgcct
     4501 tcaaaatatt gttttggccc gtcaagtagc catgtattta tctagagaac taacagataa
     4561 tagtcttcca aaaattggga aggaatttgg gggaaaagat cataccacag tcattcatgc
     4621 ccatgccaaa ataaaatctt tgattgatca agacgataat ttacgtttag aaattgaatc
     4681 aatcaaaaag aaaatcaaat aatttgtgga taacttttag ttttttatct tttttatcca
     4741 cattttttaa acaagctaaa aaacttgata tgacttgttt aaaggctgtt ttccac
//
LOCUS       DAVHSY010000074         4790 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.076, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000074 DAVHSY010000000
VERSION     DAVHSY010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4790
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.076"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            3..185
                     /locus_tag="VVR43_001979"
     CDS             3..185
                     /locus_tag="VVR43_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU6150276.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIASELVAGLR"
     gene            485..1324
                     /locus_tag="VVR43_001980"
     CDS             485..1324
                     /locus_tag="VVR43_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU6150277.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            1342..3180
                     /locus_tag="VVR43_001981"
     CDS             1342..3180
                     /locus_tag="VVR43_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU6150278.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVNQGYKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            3193..4608
                     /locus_tag="VVR43_001982"
     CDS             3193..4608
                     /locus_tag="VVR43_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU6150279.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     EEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
BASE COUNT         1637 a          621 c          930 g         1602 t
ORIGIN      
        1 agttgaagag ccagaaaatt aaagtgtctt ttactcaatc aaaaatagta acgcctattc
       61 ttttggtgaa taagactatt gtttggtatg gtgcaatgcc attattaggg aaggtagatg
      121 agatgaccat attacgtttg gaatcagcta gtatagcttc tgaactagtg gcaggtttac
      181 gatagagaaa atttttaaaa atttctatgt atgattttca tttctttagt gagactgttg
      241 tcattatcac attcgaatca cacaaaataa aaaaatttct ataagtactt gacaaataga
      301 ttgaaatatc ttaaaatgaa aatggttaca gagttattaa tgatttaagc ttcatgtcac
      361 cattaaaaat tgaaataaaa ggatgttatc actaatacaa gtgagcagga acctatttaa
      421 tcacatcgga agaagtttct tgatgttttt aagtaggttc cttttatttt aaaagggaaa
      481 ttttatgatc ataaaacgaa tactaaacca caatgccgta attgcgcaaa gtaaaaaaga
      541 tatcgatatt cttctttttg gaaggggaat agcttttgga agaaaaactg gagataaagt
      601 aaatccaatt gatattgaga aaagtttttt tctcaaaaat agagataata tgacccgttt
      661 tacagagatg tttattaacg ttcctttgga gttggtgtac atcaccgaaa aaataattaa
      721 cctaggtaaa ataacattgg gtaataattt tgatgaaatt atctatatta atttaacgga
      781 tcatatttct tcgagcatag aacgttataa agaaggagtt attatttcga atcccctacg
      841 ctgggaaatc tcgaaatatt ataaagaaga atttgaactt gggaaaaggg ctttacaaat
      901 aataaaaaaa gagttaggta ttgaacttcc aattgacgaa gctgcattca tagcgctaca
      961 ttttgttaat gctaatttag aaaataattt tcaagagtcg tataaaatca ctgaaataat
     1021 tatgggaatt gagaaaatca ttcaagattt ctattgtact gagtttaacc aagattctat
     1081 tgattattat agattcataa ctcatataaa attatttgcc catcgcttgg ttgaaaatac
     1141 aacttattgt gacgatgatg atgaagactt gttagcatta atgaaaaata aatatcctag
     1201 agaatatgaa tgtggtgaac aggtggcaat gtttatacaa actgagtaca attatttgct
     1261 gacttctagt gaattagttt atttgatggc tcatattcgt cgcttaacaa aaaatttaga
     1321 ttaatagaat aggagaatac catgagttat aaagatacgg tacaaaaaat cctcgatgta
     1381 attggaggtg aaaaaaatgt caatagagtt acccattgtg taacacgttt aagattagaa
     1441 ttaaaagatg aaaatttagt caatgatgat gatgtgaaga agataccagg tgtaataggt
     1501 attatgaaaa aaaatggaca atatcaaatt atacttggta atgatgtagc taattattat
     1561 aaagaattcg ttaaacttgg caattttgaa tccgattcag ttaatcaagg gtacaaaggg
     1621 aatattttag aaagaatcat tgagtatatc gctggttcca tgactccaat cattccagca
     1681 atgttagggg gaggtatgct gaaagtcttg gtaattattt taccaatgct tggtatattg
     1741 caatcagatt ctcagactat tgcttttttg acattttttg gggatgctcc atattatttc
     1801 ttaccgctgt tattagctta ttctgcatca caaaaattaa aagtaacatc tacattagct
     1861 atgtctgtag caggtgtact tctccatcca aattttgttc aaatggtgca atcagggaat
     1921 cctcttagtt tatttggtgc acctgtgaca ccagctagtt atggttcatc agtcgttcca
     1981 attcttatta tggtttggtt gatgaaatat attgaaaaaa taattgctaa attaacacca
     2041 gctattacta agagtttttt gcaacctacg ctagtattat tagtatcaag ctgtattgcc
     2101 ttagttgtag tcggacctat tggagtaatt gttggtgaag gattatcaaa tctagttggg
     2161 caaatgtatg gtgtagctgg atggcttaca ttagctattc ttggtgctat tatgccattt
     2221 attgttatga ctggaatgca ttgggctttt gcacctattt ttttggcggc atctattgct
     2281 actccagacg tattaattct tccagcaatg ttagggtcaa acttagctca aggggctgct
     2341 tcgatggctg ttgcattaaa gagtaaaaat aataatacaa aacaaattgc ttttgcagca
     2401 ggtttctcag ccttacttgc agggattacc gaacctgcat tatatggtgt gactttaaaa
     2461 tataaaaaac cgctttatgc agctatgatt ggtggtggat tagcgggatt atttgcaggt
     2521 cttactagtg ttaaagcata tctatttgct gtcccatctt tgatagcgtt gcctcaattt
     2581 atttattctg atgtgccatc aaatattgta aatgctttaa ttgtggcggt catttcggtt
     2641 gttattacct ttgtattagc ttatatattt ggaatcgatg aagaagagag ttctagcaat
     2701 ttagaagttg aagctggagt ttcaaataaa aaaatgatat tttctcctat atcaggagaa
     2761 atcattccgt taagcgatgt ccaggataaa acattttcag ataaactaat tggagacgga
     2821 gtagcgatta tcccaagtga aggtaaggtt tatgcaccat ttgatgggaa aattacaaat
     2881 atttttccga ctaagcacgc aattggattg aagagtgatg agggtgttga gttactaatt
     2941 catattggat tagatactgt tgagctaaaa ggtcaaggtt ttattagtca tgtagaagaa
     3001 ggagacagag ttttcaaaaa tcagttgatt tttgaaatgg acttgaattt aatcaagact
     3061 aaaggctacg aaacagttac accagtaatt gtaacgaata ccaatgattt tctagatgta
     3121 ttagtattac ctaataatca gacaatcgag cattctaagg aattactggt aatattataa
     3181 tggaggaaag ttatgaccat ttttccagat gattttcttt ggggtggagc ggttgcagct
     3241 aatcaagtag agggagcata taatgaagat ggtaagggat tatcagttca ggatgtgtta
     3301 cccaaaggtg gattaggaga agcaacagaa aatcctacag aagataactt aaaattgtta
     3361 ggtattgatt tttatcataa atataaggaa gatatatcct tgttttctga aatgggcttt
     3421 aatgtttttc gtacttctat tgcatggagt agaatttttc caaaaggaga tgaagaagaa
     3481 cctaacgaag ctgggttgaa atattatgat gaattatttg atgaactaca tgctcacggg
     3541 atagaaccac ttgtaactct ttcacactat gagactccat tatatttagc aagaaaatat
     3601 catggatgga ttgataggag aatgattcat ttttatgaaa aatttgctcg aacagtttta
     3661 gaaaggtata aagataaagt taaatattgg cttacattta acgaagtaaa ctctgttttg
     3721 gaattaccgt ttactagtgg aggaatagat atacctaagg agaatctttc gaaacaagaa
     3781 ttatatcaag ctatacatca tgaattagtc gcctcgagtt tggttacaaa aattgctcgt
     3841 gagattaatt cagagtttaa ggtggggtgt atggtattag ctatgccagc ttatccaatg
     3901 actccaaatc caaaagatgt atgggcgact catgagtatg agaatctaaa ttatctattt
     3961 tcagatgtgc atgttagagg ttattatccg aattatgcaa aaagatattt taaggaacat
     4021 gacattaaca tagagtttgc agctgaagat gcagagttat taaaaaatta tactgtagat
     4081 tttttatcct ttagctatta catgagtgtg actcaatctg ctcttccaac acagtataat
     4141 tcaggagaag ggaatattat tggtggctta gtaaatcctt atttagagtc ttctgagtgg
     4201 ggatggcaaa ttgatccaat tggactacgt ataattttaa atagatatta tgaccgttat
     4261 caaattccat tatttatagt ggaaaacgga ttaggtgcta aagatcaact aataaaagat
     4321 gaatttaata acttaacagt ccaagatgat tatagaattc agtatatgga agaacattta
     4381 ttgcaagtag ctgaagctct acaagatggt gtggaaatta tgggctatac atcttgggga
     4441 tgtattgact gcgtttctat gtccactgca caactttcta aaaggtacgg tctcatttat
     4501 gttgatcgaa atgatgatgg aaatggcaca ttcaatcgat ataagaaaat gtcctttact
     4561 tggtataaag gagtgattga atcaaatgga gaatccttat tcaaatagtt tgtttattga
     4621 tgattagata ttatcacggt taaggcaaca tctcattaaa tatgaaataa agaggtttgg
     4681 aagacatcaa attctaaacc tctttatttt atagggggat taattaattt aattttgtta
     4741 cagagagccg attataaata gtaaacttag gatagattgg ttatatatag
//
LOCUS       DAVHSY010000075         4610 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.077, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000075 DAVHSY010000000
VERSION     DAVHSY010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4610
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.077"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(143..1129)
                     /locus_tag="VVR43_001983"
     CDS             complement(143..1129)
                     /locus_tag="VVR43_001983"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU6150280.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            1323..3791
                     /gene="gyrA"
                     /locus_tag="VVR43_001984"
     CDS             1323..3791
                     /gene="gyrA"
                     /locus_tag="VVR43_001984"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU6150281.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            3791..4534
                     /gene="srtA"
                     /locus_tag="VVR43_001985"
     CDS             3791..4534
                     /gene="srtA"
                     /locus_tag="VVR43_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU6150282.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSNEILTAFNQPYKQFY"
BASE COUNT         1420 a          806 c         1028 g         1356 t
ORIGIN      
        1 taatggattg aaataagata tgaacaaatc gattaggaat ttaaagcatt ttataacaac
       61 gttttagagt aacggggtac tatttcatat aatacaggaa aaaacaactc cctgatgatt
      121 caaggagttg tctatagtta aattagtttt tagaagcttc ttggaattct ggatttttcc
      181 atgcttcgtc aataatagct tgcaattctt tagcagatgc ttgcattttt tgagtttctg
      241 catcgttcaa tggaatgttt actggacgaa cgataccatg tgcaccaaca acagctggtt
      301 gaccgataaa gacattctca actccgtatt gaccttcttg gaatactgaa agtggaagta
      361 ctgcgttttc atcgtcaagg attgctttag tgatacgagc aagggctact gcgataccgt
      421 agtatgttgc accttttttg ttgatgattg tgtaggctgc atcacgaaca ccttcgaaca
      481 attcaatcaa ttcagcttct tgaacatttt gagtgtcttt aagaaattct tcaaggttta
      541 caccagcgat gttagcgtgt gaccaaacag cgaactcaga gtcaccgtgt tcacccatga
      601 tgtaggcgtg cactgaacga gcatccacat ccaatttttc agcaagtgct tgacggaaac
      661 gagctgagtc aagtgaagta cctgaaccga taacgcgttc tttagggaaa ccagagaatt
      721 tccaagttga gtaagtcaaa acgtcaactg ggttagcagc aacaaggaag atacctttga
      781 aaccagattc aacaacttga gttacgattg atttgttgat agcaaggttt ttacctacaa
      841 ggtcaagacg agtttcacct ggtttttgag gtgcacctgc agtgatcaca acaaggtcag
      901 cgtctgcaca gtcagagtat tgagctgcat agattttttt aggtgaagtg aaggcaaggg
      961 cgtgactaag gtcaagcgca tcaccaacag ctttttcatg caattgtgga atttcgataa
     1021 ttccaagctc ttgtgcaatt ccttggttaa caagtgcaaa agcgtaagat gaacctacag
     1081 caccatcacc gacaaggata acttttttgt gttgtttagt tgaagtcatt gttttaaaca
     1141 tctccttaat tttattaggg gattttccct agacaacttc attctatcac ttttaaaaaa
     1201 ctttgtcacg aatatgcctt atagttctcg atgtaaacgt tttagtggtt tagaggctga
     1261 aatagatggg aatttatggt ataatgttgt tacttactaa ttgtgaaatg aggcatttat
     1321 taatgcagga taaaaattta gtgaatgtca atctgacaaa ggagatgaag gcaagtttta
     1381 tcgactacgc catgagtgtt atcgtagcgc gagctcttcc tgatgttcga gatggcttaa
     1441 aacctgttca ccgtcgcatt ctctacggaa tgaatgaatt gggtgtgacc ccagacaaac
     1501 cccataaaaa atctgctcgt attacagggg atgtcatggg taaatatcac ccacacgggg
     1561 attcctctat ttatgaagcc atggtccgta tggctcaatg gtggagctac cgttacatgc
     1621 ttgtagatgg tcatgggaat tttggttcca tggatggaga tagtgctgcc gctcaacgtt
     1681 ataccgaggc acgtatgagc aagattgctc tggaaatgct tcgtgatatc aacaaaaata
     1741 cagttgattt cgttgataac tatgatgcca atgaacggga acccttggtc ttgccagcgc
     1801 gttttccaaa ccttttggtt aatggagcaa ctggtatcgc ggttgggatg gcaaccaata
     1861 ttccacctca taatctgggt gaaaccattg atgcagtgaa gttggtcatg gataatcctg
     1921 aagtgactac caaggacttg atggaagtct tgcctggacc agattttcca actggtgctc
     1981 ttgtcatggg gaaatcaggt atccataagg cttatgaaac aggtaaaggt tcgattgtcc
     2041 tacgttctcg tacagagatt gaaacgacta agactggtcg tgagcgtatc gttgtaacag
     2101 aatttcctta catggtcaat aaaaccaagg tgcatgagca tattgttcgc ttggttcagg
     2161 aaaaacgcat tgagggtatc acagcagtac gtgatgagtc aaaccgtgaa ggtgttcgat
     2221 ttgttattga agtcaagcgc gacgcctcag ccaatgttat tctcaataac ctcttcaaaa
     2281 tgacccaaat gcaaaccaat tttggtttca atatgctcgc tatccaaaat ggtataccga
     2341 aaattttgtc tcttcgtcag attttggatg cttatatcga gcaccaaaaa gaagtggttg
     2401 ttcgtcgtac acgttttgat aaggaaaaag cggaagcgcg cgctcatatc ttagaaggtc
     2461 tcttgattgc gctagaccat atcgacgaag tgattcgtat catccgtgct agtgaaacgg
     2521 atgcggaagc tcaagctgag ttgatgagca agtttaagct ttctgaacgt caaagtcaag
     2581 ctatccttga tatgcgtctt cgtcgtttga caggtttgga acgcgataag attcaatctg
     2641 agtatgatga cctcttggct ctgattgcgg atttagcaga tattcttgct aagcctgaac
     2701 gtgtttctca aattatcaaa gacgaattgg atgaagttaa acgtaaattt tctgataagc
     2761 gccgtacaga gttgatgatt ggacaggtct tgagtctcga ggatgaggac ttgattgaag
     2821 aatcggatgt cttgattacc ctttctaaca gaggctacat taagcgtttg gatcaggacg
     2881 agttcactgc tcaaaaacgt gggggtcgtg gtgtccaagg aacgggagtg aaagatgatg
     2941 actttgttcg tgagttagtg tcaactagca cccatgatca tctgctcttc ttcacaaaca
     3001 agggacgtgt ctatcgtctt aaaggttatg aaattcctga gtatggtcgg actgccaaag
     3061 ggctaccagt agtcaatctc ttgaaattgg atgaagacga aagtattcag acggttatca
     3121 atgttgagtc tgatcgcagt gatgatgctt atctcttctt tacaacccgt cacggtattg
     3181 tgaagagaac cagtgttaag gagtttgcca atattcgtca aaatggtctc aaagcgctga
     3241 atttaaagga tgaagatgag ttaatcaatg tcttgttggc agaaggagat atggatatta
     3301 tcattggtac caagtttggt tatgcagttc gctttaatca atcagccgtt cgtggtatga
     3361 gtcgtatcgc cactggtgtg aaaggtgtta accttcgtga aggagacaca gttgttggtg
     3421 ccagcttgat tactgatcaa gatgaggttc ttattatcac agaaaaagga tatggtaagc
     3481 gtacagtcgc tactgaatac ccaacaaaag gtcgtggtgg taagggaatg cagacagcta
     3541 aaattaccga aaaaaatggc ttgctggccg gtcttatgac tgttcaaggg gatgaggatt
     3601 tgatgattat cactgataca ggtgtcatga ttcgaaccaa tcttgccaat atttcacaaa
     3661 caggacgtgc aactatggga gttaaagtaa tgcgcctgga tcaagatgct cagatagtga
     3721 ctttcacaac ggttgcggtg gcagaaaaag aagaagttgg gacagaaaac gaaacagaag
     3781 gtgaagcata atgtctcaaa aaaataataa aaagaaaaac aagcgaaaaa atctgctgac
     3841 aaatatccta gcaggatttc tgatattact gtcactggct ttgattttta atactcaaat
     3901 tcgaaatatt ttcatagtct ggaataccaa taagtatcaa gttagccagg tatcaaaaga
     3961 aaaattagaa gaaaatcagg atacagaagg caattttgac tttgattctg tcaaagctat
     4021 ctcttcggaa gctgttctaa cttctcaatg ggatgctcaa aaattaccag ttattggggg
     4081 aattgcaatt cctgaattgg aaatgaattt gccgattttt aaaggacttg ataatgttaa
     4141 tctcttctac ggagctggta caatgaaacg cgagcaagta atgggagaag gaaattatag
     4201 tctagctagt caccatatct ttggtgttga taatgctaat aaaatgttat tttctccttt
     4261 agataatgct aaaaatggca tgaagattta tctaaccgat aaaaataaag tttatactta
     4321 tgaaatacgt gaagtcaaac gtgtgacacc ggatcgtgtt gatgaagttg atgatagaga
     4381 tggggtcaat gaaatcacat tagtaacctg tgaagacctt gctgctacag aacgtattat
     4441 tgtcaaaggt gatttgaaag aaacaaaaga ttattcacaa acatctaatg aaatcctaac
     4501 agctttcaat caaccatata aacaatttta ttaatacaaa tcagtgaaat ccatgatttc
     4561 actgattttt taagattttc ataaaaatat agtaaaatga aataagaata
//
LOCUS       DAVHSY010000076         4303 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.078, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000076 DAVHSY010000000
VERSION     DAVHSY010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4303
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.078"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            248..>4303
                     /locus_tag="VVR43_001986"
     CDS             248..>4303
                     /locus_tag="VVR43_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU6150283.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSNSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKAVVSKNPVTDNNTSNEEARIKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAVTTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALSSNGKKTDFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSKSKTMEGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNRTSLDQDPDLFAFNNQGVHAESTSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVVS
                     REHFIRGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDDQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIPESKFKNLKN"
BASE COUNT         1664 a          637 c          832 g         1170 t
ORIGIN      
        1 ctctttgatt ttcattgagt actaatctta ttttttaacg tgtgctaaaa aataaattaa
       61 tgcatgttaa tttttcttga attaaatttt tttaaatgat atactgtttt tatggagaga
      121 taacaattat atataaatgt actactctat ttcctagata atacttagta aaacttttta
      181 taacaaaggc tagcaaagtt aaagtttatt atctattgga agttaaataa atatgtaagg
      241 aattaaaatg aaaaaaagta cagtattgtc attaaccaca gctgcagtta ttttagcagc
      301 ctatgcccct aatgaggtag tcttagcaga cacatctaac tctgaagatg ctttaaacat
      361 ctctgataaa gaaaaagtag tattagataa ggaaacagaa aataaagaga aacatgaaga
      421 tattcataat gctatagaaa cttcacagga ttttaaagag aagaaaacag cagtcattga
      481 gggaaaagca gttgttagta aaaatcctgt gacagacaat aacactagca atgaagaagc
      541 aagaatcaaa gaagattcca atcaatccca aggagatcat acggactcat ttgtgaataa
      601 aaacacagaa aatcccaaaa aagaagataa agttgtctat attgctgaat ttaaagataa
      661 agaatctgga gaaaaagcaa tcaagcaact atccaatctt aagaatacaa aagttttata
      721 tacttatgat agaattttta acggtagtgc catagaaaca actccagata acttggacaa
      781 aattaaacaa atagaaggta ttacatcggt tgaaagggca caaaaagtcc aacccatgat
      841 gaatcatgcc agaaaggaaa ttggagttga ggaagctatt gattacctaa agtctatcaa
      901 tgctccgttt gggaaaaatt ttgatggtag aggtatggtc atttcaaata tcgatactgg
      961 aacagattat agacataagg ctatgagaat cgatgatgat gccaaagcct caatgagatt
     1021 taaaaaagaa gacttaaaag gaactgataa aaattattgg ttgagtgata aaatccctca
     1081 tgcgttcaat tattataatg gtggcaaaat cactgtagaa aaatatgatg atggaaggga
     1141 ttattttgac ccacatggga tgcatattgc agggattctt gctggaaatg atactgaaca
     1201 agatatcaaa aactttaacg gcatagatgg aattgcacct aatgcacaaa ttttctctta
     1261 caaaatgtat tctgacgcag gatctgggtt tgcgggtgat gaaacaatgt ttcatgctat
     1321 tgaagattct atcaaacaca acgttgatgt tgtttcggta tcatctggtt ttacaggaac
     1381 aggtcttgta ggtgagaaat attggcaagc tattagggca ttaagaaaag caggcattcc
     1441 aatggttgtc gctacgggta actatgcgac ttctgcttca agttcttcat gggatttagt
     1501 agcaaataat catctgaaaa tgaccgacac tggaaatgta acacgaactg cagcacatga
     1561 ggatgcgata gcggtcgctt ctgctaaaaa tcaaacagtt gagtttgata aagttaacat
     1621 aggtggagaa agttttaaat acagaaatat aggggccttt ttcgataaga ataaaatcac
     1681 aacaaatgaa gatggaacaa aagctcctag taaattaaaa tttgtatata taggcaaggg
     1741 gcaagaccaa gatttgatag gtttggatct taggggcaaa attgcagtaa tggatagaat
     1801 ttatacaaag gatttaaaaa atgcttttaa aaaagctatg gataagggtg cacgcgccat
     1861 tatggttgta aatactgtaa attactacaa tagagataat tggacagagc ttccagctat
     1921 gggatatgaa gcggatgaag gtactaaaag tcaagtgttt tcaatttcag gagatgatgg
     1981 tgtaaagcta tggaacatga ttaatcctga taaaaaaact gaagtcaaaa gaaataataa
     2041 agaagatttt aaagataaat tggagcaata ctatccaatt gatatggaaa gttttaattc
     2101 caacaaaccg aatgtaggtg acgaaaaaga gattgacttt aagtttgcac ctgacacaga
     2161 caaagaactc tataaagaag atatcatcgt tccagcagga tccacatctt gggggccaag
     2221 aatagattta cttttaaaac ccgatgtttc agcacctggt aaaaatatta aatctacgct
     2281 taatgttatt aatggcaaat caacttatgg ctatatgtca ggaactagta tggcgactcc
     2341 aatcgtggca gcttctactg ttttgattag accgaaatta aaggaaatgc ttgaaagacc
     2401 tgtattgaaa aatcttaagg gagatgacaa aatagatctt acaagtctta caaaaattgc
     2461 cctacaaaat actgctcgac ctatgatgga tgcaacttct tggaaagaaa aaagtcaata
     2521 ctttgcatca cctagacaac agggagcagg cctaattaat gtggccaatg ctttgagaaa
     2581 tgaagttgta gcaactttca aaaacactga ttctaaaggt ttggtaaatt catatggttc
     2641 catttctctt aaagaaataa aaggtgataa aaaatacttt acaattaagc ttcacaatac
     2701 atccaacagg cctttaacct ttaaagtttc agcatcagcg gtaactacag attctctaac
     2761 tgacagacta aaactggatg aaacatataa agatgaaaaa tctccagatg gtaagcaaat
     2821 tgttccagaa attcatccag aaaaagtcaa aggggcaaat attacatttg agcatgacac
     2881 tttcactata ggggcaaatt ctagctttga tttaaatgcg gttataaatg ttggggaggc
     2941 taaaaataaa aataaatttg tagaatcatt tattcatttt gagtcagtag aagaaatgga
     3001 agcattaagc tccaatggca agaaaaccga cttccaacca tctttatcaa tgcccctaat
     3061 gggatttgct gggaattgga accacgaacc aatccttgat aaatgggctt gggaagaagg
     3121 atcaaaatca aaaacaatgg aaggttatga tgatgacggt aaaccaaaaa ttccaggaac
     3181 cttaaataag gggattggtg gagaacatgg tatagataaa tttaatccag caggagttat
     3241 ccaaaataga aaagataaaa atagaacatc tctagatcaa gatccagact tatttgcctt
     3301 taacaaccaa ggtgttcatg cagaatccac tagtggttct aagattgcta acatttatcc
     3361 tttagattca aatggaaatc ctcaagatgc tcaactagaa agaggactaa ctccatctcc
     3421 acttgttcta agaagtgcag aagaaggact aatttcaatt gtaaacacca acaaagaagg
     3481 agaaaaccaa aaagacctta aagttgtatc aagagagcac ttcataagag gaattctaaa
     3541 ttctaaggga aatgacgcta agggtatcaa atcatccaaa ctaaaagttt ggggtgactt
     3601 gaaatgggat ggactcatct ataacccaag aggtagagaa gaaaatgccc cagaaagtaa
     3661 ggatgaccaa gatccagcta ctaagatacg aggacaattt gaaccgattg cggaaggtca
     3721 atatttctat aaatttaaat atagattaac taaagattac ccatggcagg tttcctatat
     3781 tcctgtaaaa attgataaca cagcccctaa gattgtttcg gttgattttt caaatcctga
     3841 aaaaattaag ctaatcacaa aggatactta tcacaaggta aaagatcaat acaagaatga
     3901 aactttattt gctagagatc aaaaagaaca tcctgaaaaa tttgatgaga ttgcaaatga
     3961 ggtgtggtat gcaggagctg ctcttgttaa tgaagatgga gaggttgaga aaaatcttga
     4021 agtaacttat gcaggtgagg gtcaaggaag aaataggaag cttgataaag atgggaatac
     4081 tatctatgaa attagcggag caggagatct aagaggaaaa atcatcgaag taatcgccct
     4141 agatggagca agcaacttta ccaaaatcca taggattaaa tttgctaatc aagctgatga
     4201 aaaagggatg atttcctatt atctagtaga tcctgatcag gattcatcta aataccaaaa
     4261 gcttggcgaa attcctgaat ctaaatttaa gaatttaaaa aat
//
LOCUS       DAVHSY010000077         4245 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.079, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000077 DAVHSY010000000
VERSION     DAVHSY010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4245
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.079"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            720..1712
                     /locus_tag="VVR43_001987"
     CDS             720..1712
                     /locus_tag="VVR43_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6150284.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQKIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VVR43_001988"
     CDS             1714..2532
                     /locus_tag="VVR43_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU6150285.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VVR43_001989"
     CDS             2534..3319
                     /locus_tag="VVR43_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6150286.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3417..3635
                     /locus_tag="VVR43_001990"
     CDS             3417..3635
                     /locus_tag="VVR43_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU6150287.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3620..3817
                     /locus_tag="VVR43_001991"
     CDS             3620..3817
                     /locus_tag="VVR43_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6150288.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFLQLWNPQNPCQILIKKLE"
     gene            complement(4093..>4245)
                     /locus_tag="VVR43_001992"
     CDS             complement(4093..>4245)
                     /locus_tag="VVR43_001992"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150289.1"
                     /translation="TDVVSSKHCFEVVDRTDEVSNHTHGKATLTWFEEIFEEYKSKTF
                     VNRDTL"
BASE COUNT         1180 a          733 c          914 g         1418 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gaatgataaa attaatcaat taatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta caaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cggtgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tatttcatga
      541 gagaaatcct aatttcacaa tctataggca aacgcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttctgtagta ataaaatgta gaaggtgtag aaagtaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aacattttgt gaagattgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccaggaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgtatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg agcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaatca agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca aaagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctatc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gttaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tctccttttt gcctttttcg tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttaatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagga acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaggc agttgtcgtt gaggttttga
     3421 aggatttgcc agaatggttt ggaatcccag aaagcacaca agcctatata gaaggaacca
     3481 cgacactgca agtttggacc gcctatcagg agagtgattt gactggattt gtaaggttat
     3541 cctattcgag tgaagattgt gcagagattg attgtctcgg cgtaaaaaag cttatcaagg
     3601 tagaaaaatt gggagccaat tgcttgctac tttagagagt gaagctcgta aaaaagttgg
     3661 ttatctgcag gtcaaaacag tggcagaagg ttctaataaa gattatgatc gaacaaatga
     3721 cttttatcga ggtcttggct ttaaaaagtt agagattttt cttcaactat ggaatccgca
     3781 aaatccttgt cagattttga ttaaaaagct tgaataatat tacttgacat ctattctcag
     3841 agtgctatac tgtaagtgta atcgccgatt tagcttagtt ggtagagcaa ggcactcgta
     3901 aagcctaggt tataggtaga taaacgactg aggatttgaa aaaatagata ggtagaagat
     3961 aaccgttaag ccttactctt agcggttatt tatattgttt aatagcgctg atatttcatc
     4021 aattatgcct gttttcgtgt ttctggtagt tgttcaagtt tattgctact atttttgatg
     4081 gtatgaatgt gcttataatg tatcccggtt aacgaaagtt ttggacttat actcttcgaa
     4141 aatctcttca aaccacgtca acgtcgcctt gccgtgcgta tggttactga cttcgtcagt
     4201 tctatccaca acctcaaaac agtgttttga gctgactacg tcagt
//
LOCUS       DAVHSY010000078         4008 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.080, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000078 DAVHSY010000000
VERSION     DAVHSY010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4008
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.080"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(182..253)
                     /locus_tag="VVR43_001993"
     tRNA            complement(182..253)
                     /locus_tag="VVR43_001993"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(218..220),aa:Arg,seq:cct)
     gene            complement(295..642)
                     /gene="rplS"
                     /locus_tag="VVR43_001994"
     CDS             complement(295..642)
                     /gene="rplS"
                     /locus_tag="VVR43_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU6150290.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(761..1090)
                     /gene="crcB"
                     /locus_tag="VVR43_001995"
     CDS             complement(761..1090)
                     /gene="crcB"
                     /locus_tag="VVR43_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU6150291.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1084..1458)
                     /gene="crcB"
                     /locus_tag="VVR43_001996"
     CDS             complement(1084..1458)
                     /gene="crcB"
                     /locus_tag="VVR43_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU6150292.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(1455..1721)
                     /locus_tag="VVR43_001997"
     CDS             complement(1455..1721)
                     /locus_tag="VVR43_001997"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU6150293.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(1837..2280)
                     /locus_tag="VVR43_001998"
     CDS             complement(1837..2280)
                     /locus_tag="VVR43_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU6150294.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2384..3319
                     /locus_tag="VVR43_001999"
     CDS             2384..3319
                     /locus_tag="VVR43_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU6150295.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3373..3657
                     /locus_tag="VVR43_002000"
     CDS             3373..3657
                     /locus_tag="VVR43_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU6150296.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(3714..3932)
                     /locus_tag="VVR43_002001"
     CDS             complement(3714..3932)
                     /locus_tag="VVR43_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150297.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
BASE COUNT         1253 a          891 c          714 g         1150 t
ORIGIN      
        1 tgttgaataa attaattata caaacattta tatactcgat atagtctcaa ttttatctga
       61 tgattgccca aatttttcaa taataaaacg cataatatta tggagacaca caaaatcacc
      121 tatattatgc gttcttttaa tatcaaagac tttttgacaa acttctttga tgtctaatta
      181 ctgccccctg caggaatcga acctgcaact actccttagg agggagttgt tatatccatt
      241 gaactaaggg agctagataa aaactctgct gaaaagcaga gttttttagt cgaattaacg
      301 acgaatttct ttgatacgag ctgctttacc ttgaagagca cgcaagtagt acaatttcgc
      361 acgacgtact ttaccgtaac gaacaacttc gattttttca acacgtggag tgtggattgg
      421 gaagatacgc tcaacaccta caccgttaga gattttacga actgtgtagt tttctgagat
      481 tccagcacct ttacgtgcga taacaacacc ttcaaaaatc tggatacgtt cacggttacc
      541 ttcgacaact ttcgcatgta cacgaacagt gtcaccagga cggaatgatg ggatatctgt
      601 acgaagttga ccttcagtca agctttggat taatggattc attttattct cctatctttg
      661 tcaatcttga ggaatcttcc tcagcggata aactgtattt ttgtgcgtcc attacacaca
      721 agatatagtt taccaaattt ctaaaaaaaa gtaaagaaat ttatagcaaa attcctaaaa
      781 aaatcgcaac caaaccacct atgtaagtca aagtcaggta agaataaaag accttcttat
      841 cacttagcag tctttgaagt tcgtcattca aggtcgaaaa agttgttaaa ccgccacaaa
      901 atcctgttgc tagaatagca tatacttcct tagactctac atgattgtag aatactccaa
      961 ttaaaaaaca acctaaaaga ttagctatga gcgttccgag tggcaattta gaagcttgat
     1021 tatagcgaga aaagaaatac cgtacgagtg ctcccaagcc acaggcgatt gcaagataga
     1081 cgattaccat ttcttcctcc ccaaatagta agctaaaagc aggcctccac cgatactcaa
     1141 aagcaaatac agtatcaaac taagataacg ccctgtatca agcagcttca cagtatcaag
     1201 cattaggctg gaaaaagttg ttaaacctcc gcaaaaaccc gtccccagtg ctaaaatcaa
     1261 gcccttacta gtccccttat agaccagata gcccttgaca agataaatca agcagaaaat
     1321 tcccagatag ttgacaaaga gagtgcccca aggaaagtct ggactggctg gtaaccaggt
     1381 ggaaactaga tatcggacaa gtccgcccaa catagcagct agaaaaattc ctagcggata
     1441 aaattgttct tttttcattt gatattttga tcctgataat cacgcgaacg tttgagtatg
     1501 tccgaaaaag tcgctacaat agtctcctga tagcgcttgt cctctacacg actcctaacc
     1561 ttttcaaaaa taacttcttc tctcttagta tctaaaatcg gtttacctga agctttctta
     1621 taagcaacca ccccctcaac taaatgcatt cgttcttcta acagtttgac aatttgatcg
     1681 tcgatttgat cgatttcttg acgaataata tctaaatcca tacagtctcc tcctttattt
     1741 gaattattgt atcaaaaagc catcaattag gctagtaaaa tcccaactct cgataagaaa
     1801 aatgcactga ttgattacat cagcgcactt ttatgtttat cctactttag cagccaattc
     1861 ttctgcgaat tgttccaagc gttcaatatc ttcttcctcg gcagaaagat caactttaac
     1921 acactctgaa cctttttctg ctcctgttga cacaaagaca cggtcaaagt catcaacagc
     1981 cttacagaat tcatcgtaga aggtatctcc tgagccgacc actccgtaga ttttgccatt
     2041 caagttgaga tctgctaggt cttcgtagaa gtccatcatc tcatctggca attcaccatc
     2101 accataagta taggtcgcaa cgatagcgat gtctgcttcc aagaagtctg aagcgtcaac
     2161 agttgtacat tcatcaacat caacatccaa gcccaagtca cgtaatttgt ctgctacaat
     2221 atctgcaatt tcttcggtat taccggtcat actggcaaat acaatttttg ctaatgccat
     2281 atcgtcctcc tcaatttatc tttctccatt atatcacatc tttttcattt taaaaataaa
     2341 aattcttgtg ctacaatgaa atgagaaaga attgaggtta tttatggaga tttgccaaca
     2401 aattttagaa aaaattaaag aatacgacac cattatcatt catcgtcata tgaaaccaga
     2461 ccctgatgcc ttgggaagtc aggtgggatt gaaagccttg ctggaacatc atttcccaga
     2521 aaaaaccatc aaagccgtcg gttttgatga accaactctt acttggatgg ctgagatgga
     2581 tcttgttgaa gatagagcct accaaggcgc acttgtcatc gtctgtgata cagctaatac
     2641 tgctcgtatc gatgataagc gctatagtca aggtgatttt ctcattaaga ttgaccacca
     2701 tccaaatgat gatgtatacg gtgacctgtc ttgggtcgat actagttcaa gtagcgctag
     2761 cgagatgatt accctatttg cccaaacaac ccaactagcc ttggcagatc gcgatgctga
     2821 gttgctcttt gcaggaattg tcggtgatac aggtcgcttc ctctaccctt ctaccactgc
     2881 acggactctt cgcctggctg cttatttgag agaacataac tttgactttg cggctctcac
     2941 tcgcaaaatg gacactatga gctacaaaat tgctaaactg caaggctaca tctacgacca
     3001 tctggaagtg gatgaaaatg gtgctgctcg cgttatcctg agtcaagaag tcttgaaaca
     3061 atacaatgta accgatgctg aaactgcagc cattgtcggt gcacctggac gcattgacag
     3121 agtgagtctc tggggaattt ttgtcgaaca ggctgatggc cactaccgag ttcgcttacg
     3181 cagtaaaatc catcctatca atgaaatcgc caaggagcat gatggtggag gccaccctct
     3241 agcaagtggt gctaattcct atagcctaga agaaaacgaa atcatctacc aaaagttaaa
     3301 aaacttgctt aaaaactgat aaaatacttg ccaaactttt cagaatctga tagactagta
     3361 cggtaacaat ctatggctcg caaagagacc atggcagaaa ggaaatattg caaaatgaaa
     3421 aaagatatcc atccagaata tcgcccagtt gtcttcatgg acacaactac tggttaccaa
     3481 ttccttagcg gttcaacaaa acgctctaac gaaacagttg agttcgaagg cgaaacttac
     3541 ccattgatcc gtgtggaaat ttcatcagac tcacacccat tctacactgg acgtcaaaag
     3601 ttcactcaag cagatggacg cgtggatcgt ttcaacaaaa aatacggtct caaataatga
     3661 taagagaaca gtttcggctg ttcttttttg tttcttgaaa tcaactgctg ttttcatgtt
     3721 ccagactcat ctgtaggttc ggtttccatg ctactaggca ggaaggaaat agctgtttca
     3781 acacgtccat aatgagctgt actattgtca cgaaccacac tttcattgat ggtccaagtg
     3841 gaattcattt tcttaaaagc ttctcggact ttttccaaat ctttggaggc aatggcctgc
     3901 tctaaggttt caaaacgagg acttatactc atctgctttc acaaagcatt ctagtccatc
     3961 tccgattaac gatggacttt atcacctcct tctccagtcc ttgtatga
//
LOCUS       DAVHSY010000079         3975 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.081, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000079 DAVHSY010000000
VERSION     DAVHSY010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3975
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.081"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            371..598
                     /locus_tag="VVR43_002002"
     CDS             371..598
                     /locus_tag="VVR43_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150298.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="VVR43_002003"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="VVR43_002003"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU6150299.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYGNYNDAPLKVKPGQWNSVTFTVEKPTPE
                     LPKGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAVLTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKAFD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1361 a          660 c          877 g         1077 t
ORIGIN      
        1 gtcagtctta tccacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaatgaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacggtaa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acaccagaac tacctaaagg ccgagtgcgc
     1561 ctctacgtaa acggggtatt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt acaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggttttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttttga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtaaccaat tactaggcaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 aaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcataatgg aaaagaatac attatcctca gcaatgcagg tggaccgaat
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga atttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 tttgactcag aagtattggt caacaaggct ccaacccttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttgt ttgcagtaga taaggaagat
     3421 atcggacagg aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     3901 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     3961 atcaggaaag tcaaa
//
LOCUS       DAVHSY010000080         3900 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.082, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000080 DAVHSY010000000
VERSION     DAVHSY010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3900
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.082"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            44..1150
                     /locus_tag="VVR43_002004"
     CDS             44..1150
                     /locus_tag="VVR43_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6150300.1"
                     /translation="MEIKAYNLSKDIKDDLYKKMEDSERVHLKAEVTTILTLSISSIF
                     SFISLAVVIFVGVNLIINKEINSLYLIGYLLAAMKIKDSLDASKEGLMEIFYLSPKIE
                     RLKEIQNQDLQEGDDYSLKKFDIDLKDVEFAYNKDAKVLNGVSFKAKQGEVTALVGAS
                     GCGKTTILKLISRLYDYDKGQILIDGKDIKEISTESLFDKVSIVFQDVVLFNQSVMEN
                     IRIGKQDASDEEVKRAAKLANCTDFIEKMDKGFDTVIGENGAELSGGERQRLSIARAF
                     LKEAPILILDEITASLDVNNEKKIQESLNNLVKDKTVVIISHRMKSIENADKIVVLQN
                     GRVESEGKHEELLQKSKIYKNLIEKTKMAEEFIY"
     gene            1161..1745
                     /locus_tag="VVR43_002005"
     CDS             1161..1745
                     /locus_tag="VVR43_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU6150301.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLIIYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            1745..2440
                     /locus_tag="VVR43_002006"
     CDS             1745..2440
                     /locus_tag="VVR43_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU6150302.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            2428..3792
                     /locus_tag="VVR43_002007"
     CDS             2428..3792
                     /locus_tag="VVR43_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6150303.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNKLNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGIKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFIFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         1448 a          479 c          731 g         1242 t
ORIGIN      
        1 aagaaaaaac tcagaaagct ttcaagaaaa tatcgaaatg caaatggaga ttaaagcata
       61 taatttatcg aaggatatta aagatgactt atataaaaaa atggaagata gtgagagagt
      121 acacttaaag gcggaagtaa ctacaatttt aactttgtct atatcttcaa tatttagctt
      181 tatatctctt gctgttgtga tatttgtcgg cgtaaatcta attattaata aagagataaa
      241 ttctctctac cttataggat atttactagc tgctatgaag ataaaagact ctttagatgc
      301 atctaaagag ggcttgatgg aaatatttta tttatcgccc aaaatagaaa gattaaaaga
      361 aattcaaaat caagatttac aagaaggcga tgactatagc ttaaaaaaat ttgatattga
      421 tctaaaagat gttgagtttg cctacaataa agacgcaaaa gttttaaacg gtgtaagttt
      481 taaagctaag cagggagagg tcactgcttt ggtaggtgca agtggctgcg gtaaaacaac
      541 tatcttgaaa cttatatcaa gactttatga ttatgacaag ggacaaatct taattgatgg
      601 caaagatata aaggaaatat caacagaatc cctttttgat aaggtgtcta ttgttttcca
      661 agatgtggtt ctctttaatc aaagcgttat ggaaaatatt agaatcggta agcaagatgc
      721 aagtgacgaa gaggttaaaa gagcagcaaa acttgcaaat tgcacagatt ttatagaaaa
      781 aatggataaa ggtttcgata cagttattgg tgagaacgga gctgagctat caggaggaga
      841 aagacaaaga ttatcaatag ccagagcctt cttaaaagaa gcgccgatat tgatcttaga
      901 tgagataaca gcaagccttg atgttaacaa cgagaaaaag attcaagagt ctttaaataa
      961 tttagttaaa gataaaactg ttgtaatcat ttcacataga atgaaatcca tagaaaatgc
     1021 agacaagata gtagttcttc aaaacggaag agtagaaagc gaaggtaagc atgaagagct
     1081 tttacaaaaa tcaaaaattt acaaaaattt aatagaaaag acaaaaatgg cagaagaatt
     1141 tatttattag gaggactaca atggataata aaaaattaaa agtaaaagat ttagtaagta
     1201 tcggtgtttt tggcgtaatt tattttgcct tcatgtttgg agttggtatg atgggcttga
     1261 ttccaatatt gttcttaata tacccgacag tattagccat agttgcagga actgttgtta
     1321 tgttatttat ggctaaggtt caaaagccat gggcactatt tatatttggt atgatatcac
     1381 cacttgtgat gtttgcagct ggtcatacct acgtagttgt ggttttatca cttatagtaa
     1441 tgataatagc agaattaatt agaaagattg gtaattataa ttcatttaaa tacaatatgc
     1501 tttcttatgc aatcttcagc acatggatat gtagctcttt aatgcaaatg cttttagcaa
     1561 aagaaaaata tatggagtgg tctttgatga cgatgggaaa agattatgtt gatgtattag
     1621 aaaagttaat aatttatcct cacatggctt tagtagcctt aggtgctttc ttaggaggaa
     1681 ttcttggagc atatataggc aaggctctat tgaaaaaaca ctttgaaaaa gcaggcatcg
     1741 tataatgcct actttttctt caaatgctcc ctttaatccc aatccgatct ctaagatatt
     1801 agtcgtattt atcacaggct taactgttat gcatagcata aacatccgtt ttgagctggc
     1861 aattgtttgt cttattggta ttttgcttta tttgaatgga tacaaaaaaa cacttttcaa
     1921 atggattata ttgtgtggga tactttactc cttgcctaat tttatggtgt tatctgaatt
     1981 aaaccctata gttaagatgt ttttgagtat acctattgtt attagaatgt ttattttacc
     2041 atttatggca gcaagcttta tgataaagac ctcggatgta ggcgcaataa tttcatcgat
     2101 ggataagctt aagatttcaa agaatgtatc catacctatt gcggttatgt ttagattctt
     2161 cccatctttt aaggaggaga agaaaaacat caaaatggct atgagagtaa gagggataaa
     2221 ttttaaaaac ccagtcaaat atcttgaata tgtttctgtg ccactactca ttatatcatc
     2281 taatatatca gatgacattg caaaagcggc agaaacaaag gcaatagaaa atccaattgc
     2341 caagaccaga tacattcgcg taaagataca gctaattgat tttgtttatg ttttagcggt
     2401 tgctggactt attgtgggag gcttaatatg gttgaaataa aaaatttaag tcttgattat
     2461 ggtgaagagc atatattaga tgatatatca ctatccatag ccgagggaga gtgcgtgcta
     2521 tttacaggaa aaagtggaag tggtaagtca tctttaataa attcaatcaa tggactagct
     2581 gtaaggtatg ataacgcaaa gacaaagggc gaaataatta ttgatggtaa gaatataaaa
     2641 aatttggaac tttatcaaat ctcaatgctt gtttcaactg tttttcaaaa tcctaagaca
     2701 tattttttta atgtcaatac gacattagaa ttattatttt atttggaaaa tatcggtctt
     2761 gcaagagaag agatggacag gcgtttgaag gatatgcttg agatattccc gataaaaaat
     2821 cttttgaaca gaaatatatt taatctatcc ggcggtgaaa aacaaattct ttgcattgca
     2881 gcttcttata tagcaggtac aaagattata gttatggatg agtcttcatc gaatttagat
     2941 attaaaagca taagtgtttt ggcaaagatg ctaaagatat taaaagagaa aggcataagc
     3001 ataattgttg cagagcatag aatttattat ttgatggaca tagttgaccg tgtattttta
     3061 atagataaag gaaagcttaa aaaaacttat actagaagtg aatttttaaa gctagataaa
     3121 aataaattaa atgctttaag tttaagagat aaagaattaa gtaaattaaa agttccttat
     3181 ttaaaagaag gtggagagta tcagataaaa aatcttagct acaaatttac tgatgatgag
     3241 tgtttaagct taaaagatat ttcattcaag cttgggaaaa tttatggcat aataggatcc
     3301 aacggacgag gaaaatcaac gcttttaaga tgtttaatag gtcttgagaa aaaatcaaaa
     3361 gaagaaattt attttaaggg agagaagcta tctaaaaaag aaagactcaa aaactcttca
     3421 cttgttatgc aagatgtaaa tcatcaatta ttcacagatg aggtattcaa cgagcttaga
     3481 ttaggaataa agaattttga tgaagaaaag gcgaaaatca ttttaaaaga tttaggcctg
     3541 gacgaattta ttgaaaggca tccgatgagt ttatcaggag ggcaaaagca aaggcttgca
     3601 atagcatctg ttatgtgcaa gacttctcca tttatctttt ttgacgaacc ttcaagtggt
     3661 atggattatt ccaatatgat aaaaatatct gaactgatta ataagtataa aaccatggat
     3721 aaaataattt ttattgtttc ccatgatata gaatttttaa atgaagtggc agatgaaatt
     3781 tttgaattat aaaatagagt ctgttaaaca tgtctataga actggtaaat tgtctaaaaa
     3841 tttaaaagat actaacacat attgatattt attagaaaat taacttcagg atttttacag
//
LOCUS       DAVHSY010000081         3443 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.083, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000081 DAVHSY010000000
VERSION     DAVHSY010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3443
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.083"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(<1..107)
                     /locus_tag="VVR43_002008"
     CDS             complement(<1..107)
                     /locus_tag="VVR43_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU6150304.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTI"
     gene            complement(292..903)
                     /gene="rpsD"
                     /locus_tag="VVR43_002009"
     CDS             complement(292..903)
                     /gene="rpsD"
                     /locus_tag="VVR43_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU6150305.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1098..2150)
                     /locus_tag="VVR43_002010"
     CDS             complement(1098..2150)
                     /locus_tag="VVR43_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU6150306.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2147..2845)
                     /locus_tag="VVR43_002011"
     CDS             complement(2147..2845)
                     /locus_tag="VVR43_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6150307.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(3012..>3443)
                     /locus_tag="VVR43_002012"
     CDS             complement(3012..>3443)
                     /locus_tag="VVR43_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEU6150308.1"
                     /translation="GTQTYSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTAN
                     GSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSE
                     DKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT          962 a          764 c          660 g         1057 t
ORIGIN      
        1 taaatggtat tacgtgagat ttggaaaacg tgtgatgctt ctgttatact acctgttcgc
       61 tcacaataag agagaacttt tttacgaaaa tctattgaat atgccataaa agattatacc
      121 acattgtgta ctatttttgg ttcattttac tatatcactt tggactatat cggtctagtt
      181 atgtctaaac gattatagct ggatactaag agaaatcaaa aaagcactaa gagagaacgt
      241 cccaaagtgc ttaatatcaa ggcctcaaag cctatcttat ttaataaaat attacaacat
      301 tttgttgtag aattcaacga caagtgcttc gttgatttct gggttgattt cgtcgcgttc
      361 tggcaagcga gtcaatgaac cttccaactt ttcagcgtcg aatgatacga atgctggacg
      421 tccaagagta gcttctactg cttcaaggat tgctggaact ttcaatgatt tttcacgaac
      481 tgagatcact tgacctggag ttacgcggta tgatgggata tcaacgcgtt tcccgtcaac
      541 aaggatgtga ccgtggttta cgaattgacg agcttgacga cgagtagtcg cgagaccaag
      601 acggtaaaca acgttatcca aacgacgttc caaaagaagc ataaagttga aacctaggat
      661 tccgcctttg atttttgtag cttgtacgaa caagttacgg aattgttttt cacctacacc
      721 gtaagtgaaa cgaagttttt gtttttcagc caattgcaaa ccgtattctg acaatttaga
      781 acggttgttt ggtccgtgtt gtcctggtac gtagttacga cgtgccaatt ctttacctgt
      841 acctgtaagt gaaaggccaa ggcgacgagc ttgtttccaa gatggtcctg tataacgtga
      901 catatgaatg tcctcctgat ataaataata tttcggtgga aatagtcact tagaaagccc
      961 tgattcgtgc agatgccctt cgcctaaaca gccaaggtta cttgtcataa gacacctgtt
     1021 gacgagcttc atgctttcct gctgatattt cacacaaaat ctattctacc atgaatagct
     1081 ggatttgtaa aggggtttta ggctttattt tcactaccag agaggttgag aacgagggta
     1141 aaggtacttc ctagaccgta ctggctgctg actgtgattt ccccacccaa ttgatgggcc
     1201 aattcacgcg caatcgcaag tcctaatcca tgaccacctg tcttcatgtt acgcgaagtt
     1261 tcgacacgat aaagacgttt gaaaatattt tccaaatcct ctggggcaat accctgccct
     1321 tcatcggtca cactgattga aagctggtcc ttctccagct tagccaccac ttccagcttg
     1381 gttcctggag cagaatattt aaaagcgtta tcgaccagat tcaccaagat acgagaaagc
     1441 ttagcataat ctccctcaat ccgggcagac tctgggatta cctgcaagtg gacatctctt
     1501 ctctcctgct caatcaaaaa ctgaaattca ctcatgcact caattaagag cttgtccaga
     1561 aaaatactgt ctttactggt agtttccacc tgatttctag ctgtgtttag ggtcaaaaaa
     1621 ttcaactcct caaccagttt attgagcctc tccgtctggc gtccaatggt tgctagataa
     1681 tgagcttgct ccgactcctt gataatccca tccaaaatcc cttctaccgt cgcttgaatc
     1741 gaagtgatag gggtcttaat atcatgcgac aactgggcaa tcatcaagcc cttttctcgt
     1801 tcgctttctt ccaaggaatc aaagcttacc tgcaaatcat gggacatctc attaaaagtt
     1861 tgccctaatt gctgaaattc tacaggacct tgaacctcca aatttgaagg aaaatccttg
     1921 gccgctaccc gcttggcatg ctccttgagt ttgcccaacg acgtaaagac tggcaatagg
     1981 agaaagagac taatcccagc accgacaagg ctggcaacga tggtcatccc aagcaaaaag
     2041 taaatctcgc ctttcgcaat cagcattttt tgaacagccc aaaaaacaac caaaatggtt
     2101 aagagggttg aaataatata tccaaccaaa atataacttt ttagtttcat gtttgtcctc
     2161 tcggtttctc tatcttatat cccaaccccc aaactgtctt aatagtgggc gtttggtcac
     2221 tactatattt tgccagctcc tgtcgaagag catggatatg cacattcaag gtattggtgt
     2281 catccacgta gtcttctttc cagatctttt catagaggtc tgtcttggag aaaactcgct
     2341 ctggattgct agctaaaatc cacagcaatt caaatgattt aacagttaaa tccagcattt
     2401 cttctcctat ttgaacttca tgactactat gattcatttt tagattgcca agggaaatca
     2461 gctctgtttc gcccccacga tgaaggcggc gcaaaatatt gtggacacgc aaaaccagct
     2521 cacgtgggct aaaaggctta gcaataaaat catctgctcc caagctcagg ccgtaaatct
     2581 tgtcctgttc actggtctta gcagtaataa ataggaaagg ctgctctggt gataagtatt
     2641 gaacctcact gattaaatca taaccatcca tccgaggcat catgacatct gtgataatca
     2701 aatcaatcgg ttttttcttg aacagctcta gcgcttccag tccatcatgg gctaccaaga
     2761 cctgataacc tgcctgaatt aagtatctct gatgaatatc tgtgatttct acctcgtcgt
     2821 caacgagtaa aattgtcttt cccatctgtc tctcctttga taaaaacagt gctatactgc
     2881 tttaagtata acactatttt tattgtttta cgatgatttt aatctgctat tgaaagaaag
     2941 tcctgattgc tgattgagtt gttaaactaa tcttagtcag cccactatcc atcatttatt
     3001 tccttagctg attagttttc ttcttttttg tttttcaaac ctagaccacc gagtaaacct
     3061 gcaagcgcaa gcccaaggaa accaatactt gccattgatg tttgagtctc accagtattt
     3121 ggtagcatag ctttatcctc tgacatcatc gtatcagaca tcttgttagc agaagcagcc
     3181 atgttttcac ctgccatcgt gttggtagaa cttgtcatgg tgtcagcagg catgctatct
     3241 gtagtacctg tagcatgatt gtgattcatc ggagtcacgc cagaaccaga gttagaaggt
     3301 gataatgaac catttgctgt gtctgatgtt tctttaacat ttatcttaat agtgactttt
     3361 ttagttgcta cgatgttgtc caagtctggt ttaccgtctt tgttaccata gacattgact
     3421 gtagcgctgt aagtttgagt acc
//
LOCUS       DAVHSY010000082         3362 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.084, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000082 DAVHSY010000000
VERSION     DAVHSY010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3362
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.084"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(249..1739)
                     /gene="lysS"
                     /locus_tag="VVR43_002013"
     CDS             complement(249..1739)
                     /gene="lysS"
                     /locus_tag="VVR43_002013"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU6150309.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINELFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(1867..2013)
                     /locus_tag="VVR43_002014"
     CDS             complement(1867..2013)
                     /locus_tag="VVR43_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU6150310.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            2228..2908
                     /locus_tag="VVR43_002015"
     CDS             2228..2908
                     /locus_tag="VVR43_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6150311.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANIIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFG
                     NPSTLSRK"
     gene            2868..>3362
                     /locus_tag="VVR43_002016"
     CDS             2868..>3362
                     /locus_tag="VVR43_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6150312.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTS"
BASE COUNT          908 a          707 c          680 g         1067 t
ORIGIN      
        1 gtgaatctga acaaatcaat tggggaatcc aagtcaattt ctagtacttt ttgaacagtt
       61 tcagcgtact atcgtaaaat gaaataaaac atgcacaaat tgattaggga atttaaacca
      121 atttctaaca atgtcttaga aatcaaagtg tactatttca acttcaatat actacacttc
      181 attttctcct taaattcagt ctctttttga atcaaaaaat cctctggtaa gagccagagg
      241 ataagaattt atttcattgt tgggaagagc aatacatcac ggatagttgt tgtatcagtg
      301 aggagcatgc agagacggtc gataccgatt cccaaaccac ctgttggtgg cataccgtat
      361 tcaagagctt caatgtagtc atagtcgatt cctgtcgctt catcatcacc aagttctttg
      421 gctttagctt gggcttcaaa acggctaagt tggtcgattg ggtcgttgag ttcagtaaag
      481 gcattaccgt actccttagt catgataaag agctcgaaac ggtcagtaaa gcgttggtct
      541 tcaggatttt tcttagcgag tggagataca gctactggat gtccatagac aaaggttggt
      601 tggattaaag tttcttcaac aaactcttca aagaaggcat tgatgatgtg accaacctca
      661 gtgtagtgtt tctcaactgg aactttcttc tcagcagcga tagctttagc ttcttctaaa
      721 gtcatgtctt gccagaaatc gacaccagta atttctctga tagcatccac catatgaaca
      781 cgcttaaata gttcgttaat cttgatttca gtaccttggt agttgactgg gccatcgccc
      841 ttaactgatt tagcagcgtg ttggataatg ccttccgtca agtccatgat gtcttggaag
      901 tctgcataag cttggtaaac ttcgatagaa gtaaactcag ggttatgagt agcgtccatt
      961 ccttcgttac ggaagatacg gccaatttca tagacacgtt ccataccacc cacgataagg
     1021 cgttttaagt gaagctcagt cgcgatacga agcaccatgt caatgttttg ggcattgtgg
     1081 tgggtgataa atggacgggc agcagcacca ccggcttcat tatgaagaac aggtgtttcc
     1141 acttcaagga atcctttttg gtcaaggtaa cgacggattt cagagatgat ttttgaacga
     1201 gtgacaaagc gttcaaagct ttcacggtta gaaatcaagt caaggtaacg tttacggtaa
     1261 attgtttcaa cgtctgtcaa accatggaat ttctcaggaa gaggacgaag agccttagac
     1321 aagtgtgtga tgtgggttgc cttgatagag agttctccca tatccgtacg catcacttca
     1381 ccttcgacac caaggaagtc accaaggtct gcttttttga agatttcgta gttttcttca
     1441 ccgacagcat ccttacgaac gtagatctga atctggcctt cgcggtcttg aaggtgggca
     1501 aaaccaactt ttcctttacc acgtttggtt atcaagcgtc ctgcgatagt agctgtttcg
     1561 tttttatcgt gtaattgttc tttatcgagg ttggcatatt tatcttttaa ttcttgtgaa
     1621 tttgcagtac gttcaaaacg ttttccgaaa ggatcgattc cttgttcgcg gagcgcagcc
     1681 attttttcac ggcgaacgat ctgctggtca tttagttctt ccatatgttc tgtagacatg
     1741 ggatcctcct agttttactc aaaattgaat acgatgagtc attttttgcg atactcccat
     1801 tttatcataa ataagcaaga aattcacgga taatctttaa aaactaaaaa gaacctgacg
     1861 ctaaaatcac tggaaagaag tgaaagtatc tcccgcccca ctagcgatat agccaaatgc
     1921 tgctttagga ataacttgtt gcgccattgg ctccaaatca taggtattga tgaaatctac
     1981 atgaccttct gcattgcttg ttttgtatga cataaaatgc cctccttgat aagtaagcgt
     2041 ttactttgta tattacaaaa atatcttaac tctttttcaa aacttttcaa atattttgtt
     2101 tggaaatttc agaaatttta tgtctatggt aaaaaatcct tataacggca ataaaaaata
     2161 gatattatcc aaagaagatt ttaagtgcta caataactgt attatttcta gatgggaggt
     2221 tctatttttg gattggtcca ttgttgaaca atatctacca ctatatcaaa aggcattctt
     2281 tctgaccttg catattgcag tttggggaat tttgggatcc tttctgctcg gtttaatcgt
     2341 tagtatcatc cgacattatc gaatccctgt tttggcgcaa gtagcgacag cctacattga
     2401 attgtcacgt aatacgcccc ttttgattca actcttcttt ctctacttcg gtcttccccg
     2461 aatcgggatt gtcctatctt cagaagtctg tgcaacgctt gggcttgtct ttttaggagg
     2521 ctcctatatg gcagaatctt tccgaagtgg gctggaagcc atcagtcaaa cccagcagga
     2581 gattggcctc gctattggtc tgacacctct acaggtcttt cgctatgtgg ttcttccgca
     2641 agcaacagcg gtggcactcc cctcctttag tgccaatatc attttcctta tcaaggaaac
     2701 ctctgttttc tcagcagtgg ctttggccga cctcatgtat gtcgccaagg atttgattgg
     2761 tctctactat gagacagaca ttgcgctagc tatgttggta gttgcttatc tgatcatgct
     2821 gctacccatc tcactggtct ttagctggat agaaaggagg ctccgccatg caggattcgg
     2881 gaatccaagt actctttcaa ggaaataatc tcctgagaat cttacaggga ttgggcgtta
     2941 cgattgggat atccatcctg tctgtcctct tatccatgat gttcggaaca gtcatgggaa
     3001 tcatcatgac ctcccattct agaatcatac gatttttaac acgattgtat ctggaattta
     3061 tccgtatcat gccccagctg gtgctactct tcatcgttta ctttggcttg gctcgaaact
     3121 ttaatatcaa tatctcaggt gagacttcag ctattatcgt ttttaccctc tggggaacag
     3181 ctgaaatggg agacttggta cgtggagcta tcacttctct ccctaaacat cagtttgaaa
     3241 gtggacaggc actcggcttg actaatgttc aactttacta ccacatcatc atcccacaag
     3301 tcttaagaag actgctaccg caggctatca atcttgtcac tcggatgatt aaaaccactt
     3361 ca
//
LOCUS       DAVHSY010000083         3163 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.085, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000083 DAVHSY010000000
VERSION     DAVHSY010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3163
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.085"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(<1..564)
                     /locus_tag="VVR43_002017"
     CDS             complement(<1..564)
                     /locus_tag="VVR43_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150313.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCIGDFPHDFFDTYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRLFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFN"
     gene            complement(578..1291)
                     /locus_tag="VVR43_002018"
     CDS             complement(578..1291)
                     /locus_tag="VVR43_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU6150314.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1750..2130)
                     /locus_tag="VVR43_002019"
     CDS             complement(1750..2130)
                     /locus_tag="VVR43_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEU6150315.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLVFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQIQLAELEINK"
     gene            complement(2552..>3163)
                     /locus_tag="VVR43_002020"
     CDS             complement(2552..>3163)
                     /locus_tag="VVR43_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU6150316.1"
                     /translation="MPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYT
                     LEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQTEKP
                     EEETPREEKPQSEKPESPKPTEEPEEESPEESEEPQVETEKVEEKLREAEDLLGKIQD
                     PIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLALLKESK"
BASE COUNT          977 a          610 c          500 g         1076 t
ORIGIN      
        1 attaaaatcc atttcagaaa aaggagtttc tttagaaact tgccatatag tctttaaata
       61 atttttttct aaaaagtcat caaaattaga aaacaatcga aaatacaatg cattctcttg
      121 gtgtaaaatc gctcttttta aaggataata ctctttaata ttattaactt tttgttcgta
      181 ggcatatttt gctacatgat ctaggtatgt atcaaaaaag tcatgaggaa aatctcctat
      241 acagccatta cgattcatat tgaggctata ttttcgatta gtaagataat tcggaaatat
      301 atttcctatt actctaagat tatctacttg tgaatccctt ctcccaatat aatccccttc
      361 tttgactaat gatggagatt tccaagtaaa aattaaatcg ccagagaaat ttttcttatc
      421 aaaaaactta aaaagagatt gataaatact atttgctaat tgacaagtgt cagatgtaaa
      481 ttcataatta acagcttcat taaaatcaac ttcagacatt tcaatgtact cttcaatagt
      541 aatattagct ttttttgtag tcattagcta atctccttta aaacgtgatc ttttcaagaa
      601 tatttttatc taaacaatcc agcaagtctt ggtaagaata gacttcgtaa gtcggctggg
      661 cttgtgtgtg attttcgagg tgatgaggat tataccagat agtgtcaatc cccgcattat
      721 tgccaccttg aatgtcggcg gttagagaat ctccaatcat cagcgtcttt tctttactaa
      781 atccagcaat ttgctggcca atcttttcat aaaaaagagc atccggcttt tgagtttgca
      841 actgttctga gataaagact tgattgaaat aaggtgctag accagattga gccaaacgtc
      901 ctgtctgaat ggcagtaatg ccatttgtcg cagcatacaa gttataatca cgctcaatga
      961 ggctgtccaa gagatcatga gcgcccgata gtgtttgtcc ctgctgggcg aggtaaaatt
     1021 ggtaacgctg ggcaagaaaa ctaccgtctt tttcctgtcc aaaatgagca aataaacgag
     1081 aaaagcgcgt gttaaccagc tcttgtttac tgattttctt cagctccaag tctttccaga
     1141 gagccttgtt cataggaacg taataatctt tataagcctg aatatccgca actccttctt
     1201 cttttagaag ttgggtcaaa gccacatcct cagcagcatc aaaatcaaga agagtgtggt
     1261 cgaggtcgaa gagtagaaat ttgtagaaca atttgaggtt ttcctttctg aaaattcatt
     1321 aagaacatta tatcataaag cacctcatac aattaactaa tttaatcact taaaaaaaat
     1381 tcgaacactt tctatacaac tgacagctca aatctttcag aatagaacaa tactaactat
     1441 ccagcacccc atcttcataa atatatgtgt aattctagac ctagaattcc tataaactaa
     1501 atgctttcat actcttccaa gtaattgatt tccttaaatt ttaatttttg aaggattcta
     1561 aagctagaat agccccatca caatcagttt tgattgattc acaatttaga aacactatag
     1621 tttcactcct gttaaaataa aaaggaattg cataaagcaa tccctttctg attttgaaat
     1681 catttactta acattttata gttgagataa tcaatagctt acctataaaa agagttatag
     1741 taaaattcct tatttattga tttcaagctc cgctaactgt atttgaataa ctgacagttc
     1801 tgcaccagcc tgaagaagag cagctgcatt ataggcacct tctacaattg gaaccctgtt
     1861 gatgatgata cttttatcac tgaaatcagt caccattttt aagttcattt tagcagaacc
     1921 taggtcaaaa aatacaagta aagtatctgc tggattttcg gaaacaaccc tatctacttg
     1981 atcaaaactc gttccaattc ctccgccctc ggttcctcct acataagtaa tcggaacatc
     2041 tttagctact ttactaatca gttcaacaac accttccgca atgtgtttgg aatgtgaaac
     2101 gataacaaga ccaataccaa tactttccat caaaccaccc cagtttctaa aatagcagta
     2161 aagagtaatc ctgatgagaa tgatccagga tcaatatgtc caagaaacca catgctccta
     2221 agacaagagc taacagactg gccatcaata atagtattgt tctttttttc atcattactc
     2281 cttaactagt gtttaactga ttaattagcc agtaaatagt ttatctttat ttacactatc
     2341 tgttaagata tagtaaaatg aaataagaac aggacagtca aatcgatttc taacaatgtt
     2401 ttagaagtag aggtatacta ttctagtttc aatctactat attttgcaca ttttcatgaa
     2461 aaaaatgaga actagaactc acattctgct ctcatttttc gttttcccgt tctcctatcc
     2521 tgtttttagg agttagaaaa tgctgctacc tttacttact ctcctttaat aaagccaata
     2581 gtttttcagc ttctgccata atagtattgt tgtcctgggt gccaaatagt aaattatttt
     2641 ttaatcctgt gagagtctct ttggcattgg acttgataat tggatcctgg atttttccaa
     2701 gtaaatcttc agcctctctc agtttttctt caaccttttc agtctcgacc tgaggttctt
     2761 ctgattcctc tggtgattct tcttctggtt cctctgttgg ttttggagac tctggtttct
     2821 cgctttgcgg tttctcttct cgaggggttt cttcctcagg tttttctgtc tgaggtttct
     2881 cctcgtttgg tttctccgtt tgattggtat cagcttgacc atttttgttt ctttgaacat
     2941 ggtcgctagc gttaccaaaa ccattatctg aatgcggacg ttcgtttgga tgttcgacat
     3001 agtacttgac agtcgccaaa agatcctcaa gagtataccc cttaggtgcc tcataaaggc
     3061 cttcgtcaaa ccactcaaat ttgatgttat ggtaatggtc ataatgaggt atgattaaac
     3121 taccgttttt gacttctaca gtatattgaa gattgtaagg cat
//
LOCUS       DAVHSY010000084         2810 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.086, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000084 DAVHSY010000000
VERSION     DAVHSY010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2810
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.086"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..264
                     /locus_tag="VVR43_002021"
     CDS             <1..264
                     /locus_tag="VVR43_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6150317.1"
                     /translation="PKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPL
                     PPLALQNEFADFVVQIDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            324..560
                     /locus_tag="VVR43_002022"
     CDS             324..560
                     /locus_tag="VVR43_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEU6150318.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            557..970
                     /locus_tag="VVR43_002023"
     CDS             557..970
                     /locus_tag="VVR43_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEU6150319.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            1088..2053
                     /locus_tag="VVR43_002024"
     CDS             1088..2053
                     /locus_tag="VVR43_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6150320.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKVQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            2087..>2810
                     /locus_tag="VVR43_002025"
     CDS             2087..>2810
                     /locus_tag="VVR43_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6150321.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIMVSYTNLREQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGDVILNEKEWKVSKWNEILTIRNGKNQKQVEDADGKFPIYG
                     SGGIMGYAKDWIVKKNSVIIGRK"
BASE COUNT         1027 a          402 c          558 g          823 t
ORIGIN      
        1 cccaagacac caaatctaaa tcagaaattt attatccatg ttttaaggaa taataattat
       61 agtcgagtga tatcaggaag tgctcagcct cagttaccaa ttacaaaatt aaaaaaaata
      121 cttctccccc tccccccact agccctccaa aatgagttcg cagactttgt agttcagatc
      181 gacaaatcac aattggcaat ccaaaaatct ctggaagaac ttgaaacttt gaagaaatct
      241 ctgatgcagg agtattttgg ctgatattct gccattgtaa ttacggtaat gatttgttat
      301 aatacttcaa aggaggaaat cagatggtag taaaaacaag aaaacaagga aattcaatca
      361 ccattacgat tccaagtgaa tttaatattc caagtggtgt taaatacgaa gcgaaattgt
      421 taccaagtgg tgagattatc tttactcctg aagaattggg gcagcaggtt tcttatgtat
      481 ctgatgatgc ctttgactta aatttagata aaatatttga cgaatacgac gatgttttca
      541 aagctttggt ggaaaaatga caatctatct gacagaaaag caaattgaaa aaataaatgc
      601 tttagcaatt caacggtatt ctccaaatga gaaaattcaa acagttagtt cttctgcctt
      661 aaatatgatt gtgaacttac cagaacaatt tgtctttggg aagtctcttt atccaacaat
      721 ttttgataaa gcaacgatac tatttgtcca attgataaag aagcatgttt ttgctaatgc
      781 taataaaaga actgctttct tcgttttggt caaattttta caattaaacg gctatcgttt
      841 ttctgtaacg gtagaagaag cagtaaaaat gtgtgtaacc atcgcagtag aagctttaac
      901 tgatgaaaaa atgacaagct actccaaatg ggtttctgaa cattctgtta gagaaaaggt
      961 caaaaagtaa cctagtatgc tggatttgaa tgagcacaag aaaataaatg aacagacaat
     1021 attagaattc tgtaatgcag aaactgatat tgtctctttt tattgatgaa taagaaagtg
     1081 agaaattatg gaatcaaaag ttacaattat catgcaagaa atgttacctc ttttaaataa
     1141 tgaacaatta ctagcgttga gagagagttt agaacatcat ctagtagacg gaaaaaagca
     1201 gcagaagtat tcgaataata acctgttgca actatttatt accgccaagc aggtagaggg
     1261 ctgtagctca aaaacaattc gttattacca gaggacgatt gaaaacttgt ttaatgctat
     1321 taaagagtct gtgacacaac tcacaacaga tgatttaagg agttatttag caaattacca
     1381 gtctgaaaag gattgtagta aggcaaattt agacaatatt aggcgtatat tgtcttcttt
     1441 ttttgcttgg cttgagcaag aggaatatat cattaaaaat cccattcgac ggataaagaa
     1501 aattaagact gagcaaaatg tgaaggaaac ttatactgat gaacatttgg aaattatgcg
     1561 tgataactgt gaaaatttga gagatttggc aataatagac ctactagcat cgacaggtat
     1621 gcgtgtaggg gagcttgtac agttgaatcg ttcagatatt gattttgaaa acagagagtg
     1681 tgttgtcttt ggtaaaggaa agaaggagag accagtatat tttgatgctc ggacgaaaat
     1741 tcatttaaga aattatctta acgacagaaa agatagtcac cctgctcttt ttgtaacgct
     1801 agttggaaaa gtccagagac ttggaattgc tggtgtagag attcgcttaa gaaagttagg
     1861 agacaaactc ggcatacaaa aggttcaccc acataagttc agaagaactt tagcgactaa
     1921 ggcaattgat aaaggtatgc ctatcgaaca agtccaaaaa ctgctaggtc atagcaagat
     1981 tgacacaacc ctggcctatg ccatggtcaa tcaaaataat gtcaagcatt cacaccaaaa
     2041 attcatctct taaaagcaaa tcccgatatt ccgaggaggt ggttgcatga agaaagtgaa
     2101 attagggcaa gtggctactt ttatcaatgg ctatgctttt aaacctcaag attggtcatc
     2161 tgaagggaaa gagattatca gaatacagaa tctgactaaa acttcaaaag ggataaatta
     2221 ttattcgggt acgattgata aaaaatacat tgttgaagct ggtgatattc ttatttcgtg
     2281 gtcgggtaca ttaggggttt ttcagtggtg tggaagatcc gcagtgttaa atcagcacat
     2341 ttttaaagtg gtttttgata agatagatat agataaatcg tattttaaat atgttgttga
     2401 aaaaggtttg caagatgctg taaaacatac tcatggttcc acaatgaaac atttaactaa
     2461 aaaatatttt gataatatta tggtttcata tacaaatttg agagagcaac aaagaattgc
     2521 aagtgagctg gatttgttaa gcaagctgat tttaaggaga caagaacaac ttgaagagct
     2581 taatctactt gtaaaatccc gatttaacga gatgtttggg gatgttattc taaatgaaaa
     2641 agaatggaaa gttagcaaat ggaacgagat tctaacaata agaaatggta aaaatcaaaa
     2701 acaggttgaa gatgctgatg ggaaatttcc tatttatgga agtgggggaa ttatgggata
     2761 tgctaaagat tggatagtga agaaaaattc agttattatt ggacgtaaag
//
LOCUS       DAVHSY010000085         2764 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.087, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000085 DAVHSY010000000
VERSION     DAVHSY010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2764
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.087"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..2332
                     /locus_tag="VVR43_002026"
     CDS             <1..2332
                     /locus_tag="VVR43_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6150322.1"
                     /translation="NLLVDNQSIEGKSLFNIHKTISTIRDFENKDLKKLIKKKYKQED
                     DFVNGGTRTVERDYKYDDKGNIIAYDDGTDLEYETEKLDEIKSKIYGVLSPSKDGHFE
                     ILGKISNVSKNAKVYYGNNYKSIEIKATKYDFHSKTMTFDLYANINDIVDGLAFAGDM
                     RLFVKDNDQKKAEIKIRMPEKIKETKSEYPYVSSYGNVIELGEGDLSKNKPDNLTKME
                     SGKIYSDSEKQQYLLKDNIILRKGYALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKAN
                     PNLRVLSETTIYADSRNVEDGRSTQAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDG
                     NLVTDSSKLVLFGKDDKEYTGEDKSNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKS
                     NKIYVRNPEFYLRGKISDKGGFNWELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKD
                     GDIMDWGMKDYKANGFPDKVTDMDGNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNI
                     DPKGNTSIEYADGKSVVFNINDKRNNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTL
                     NIKIVVKDFARNTTVKEFILNKDTGEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILP
                     VYKGELEKGYQFDGWEISGFEGKKDAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFD
                     VSKKKDNPQVNHSQLNESHRKEDLQREDHSQKSDSTKDVTATVLDKNNISSKSTTNNP
                     NKLPKTGTASGAQTLLAAGIMFIVGIFLGLKKKNQD"
BASE COUNT         1102 a          350 c          520 g          792 t
ORIGIN      
        1 taacctttta gtagataatc agtctatcga aggaaaatct ctctttaata ttcataaaac
       61 tatttcaaca attagagact ttgaaaataa agacctaaag aaactcatta aaaagaaata
      121 taagcaagaa gacgactttg taaatggtgg aacaagaaca gtagagcgtg attataaata
      181 cgatgataaa ggaaatataa tagcctacga tgatgggact gatctagaat atgaaactga
      241 gaaacttgac gaaatcaaat caaaaattta tggtgttcta agtccgtcta aagatggaca
      301 ctttgaaatt cttggaaaga taagtaatgt ttctaaaaat gccaaggtat attatgggaa
      361 taactataaa tctatagaaa tcaaagcgac caagtatgat ttccactcaa aaacgatgac
      421 atttgatcta tacgctaata ttaatgatat tgtggatgga ttagcttttg caggagatat
      481 gagattattt gttaaagata atgatcagaa aaaagctgaa attaaaatta gaatgcctga
      541 aaaaattaag gaaactaaat cagaatatcc ctatgtatca agttatggga atgtcataga
      601 attaggggaa ggagatcttt caaaaaacaa accagacaat ttaactaaaa tggaatctgg
      661 aaaaatctat tctgattcag aaaaacaaca atatctgtta aaggataata tcattctaag
      721 aaaaggctat gcactaaaag tgactaccta taatcctgga aaaacggata tgttagaagg
      781 aaatggagtc tatagcaagg aagatatagc aaaaatacaa aaggccaatc ctaatctaag
      841 agtcctttca gaaacaacaa tttatgctga tagtagaaat gttgaagatg gaagaagtac
      901 ccaagctgta ttaatgtcgg ctttggacgg ctttaacatt ataaggtatc aagtgtttac
      961 atttaaaatg aacgataaag gggaagctat cgataaagac ggaaatcttg tgacagattc
     1021 ttctaaactt gtattatttg gtaaggatga taaagaatac actggagagg ataagtccaa
     1081 tgtagaagct ataaaagaag atggctccat gttatttatt gataccaaac cagtaaacct
     1141 ttcaatggat aagaactact ttaatccatc taaatctaat aaaatttatg tacgaaatcc
     1201 agaattttat ttaagaggta agatttctga taagggtggt tttaactggg aattgagagt
     1261 taatgaatcg gttgtagata attatttaat ctacggagat ttacacattg ataacactag
     1321 agattttaat attaagctga atgttaaaga cggtgacatc atggactggg gaatgaaaga
     1381 ctataaagca aacggatttc cagataaggt aacagatatg gatggaaatg tttatcttca
     1441 aactggctat agcgatttga atgctaaagc agttggagtc cactatcagt ttttatatga
     1501 taatgttaaa cccgaagtaa acattgatcc taagggaaat actagtatcg aatatgctga
     1561 tggaaaatct gtagtcttta acatcaatga taaaagaaat aatggattcg atggtgagat
     1621 tcaagaacaa catatttatg taaatggaaa agaatataca tcatttgatg atattaaaca
     1681 aataacagac aagacactaa acattaagat tgttgtaaaa gattttgcaa gaaatacaac
     1741 cgtaaaagaa ttcattttaa ataaagatac gggagaggta agtgaattaa aacctcatag
     1801 ggtaactgtg accattcaaa atggaaaaga aatgagttca acgatagtgt cggaagaaga
     1861 ttttatttta cctgtttata agggtgaatt agaaaaagga taccaatttg atggttggga
     1921 aatttctggt ttcgaaggta aaaaagacgc tggctatgtt attaatctat caaaagatac
     1981 ctttataaaa cctgtattca agaaaataga ggagaaaaag gaggaagaaa ataaacctac
     2041 ttttgatgta tcgaaaaaga aagataaccc acaagtaaac catagtcaat taaatgaaag
     2101 tcacagaaaa gaggatttac aaagagaaga tcattcacaa aaatctgatt caactaagga
     2161 tgttacagct acagttcttg ataaaaacaa tatcagtagt aaatcaacta ctaacaatcc
     2221 taataagttg ccaaaaactg gaacagcaag cggagcccag acactattag ctgccggaat
     2281 aatgtttata gtaggaattt ttcttggatt gaagaaaaaa aatcaagatt aagacaaaag
     2341 ctatagaaaa aaatggttta tgtactgaga ttagatagtg aggtgatgac atagttttgt
     2401 gaaaacggcc atttataact caattattta gtttacttca cttcactatt gatactattt
     2461 ggagttatta atggacttag tttagataac taatgaattg attgaaaggg ttagtattga
     2521 caatattggt catattgatt agaaaataga gtctatcaaa atttaaaggc taatagaggt
     2581 gatgagacaa tttcaaggaa ttaagtagcg tttggttgct taattccttt ttatttggaa
     2641 ggaagttttt cgtaaccgcc caataacgaa gtctattgga cggttacgat atgatcactg
     2701 acttcgtcag tcttatctac aacctcaaaa ctgtgttttg agcaacctgc ggctagcttc
     2761 ctag
//
LOCUS       DAVHSY010000086         2751 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.088, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000086 DAVHSY010000000
VERSION     DAVHSY010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2751
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.088"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            13..789
                     /locus_tag="VVR43_002027"
     CDS             13..789
                     /locus_tag="VVR43_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150323.1"
                     /translation="MSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKESFLLIK
                     EKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKGNLFFPP
                     LGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTIYRCLRT
                     FKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSVSNLLYG
                     GAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQYVLK"
     gene            793..990
                     /locus_tag="VVR43_002028"
     CDS             793..990
                     /locus_tag="VVR43_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150324.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            980..1531
                     /locus_tag="VVR43_002029"
     CDS             980..1531
                     /locus_tag="VVR43_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150325.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNLEFPSMIELFSIL
                     PEYPLKKDGREISLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCGLYSSTI
                     SSNHVSFHLQPQNSVLSSLRLAS"
     gene            1590..1850
                     /locus_tag="VVR43_002030"
     CDS             1590..1850
                     /locus_tag="VVR43_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150326.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELELVKSTILQNDDISLDQNEIFEILKNFFDG"
     gene            complement(2588..>2751)
                     /locus_tag="VVR43_002031"
     CDS             complement(2588..>2751)
                     /locus_tag="VVR43_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEU6150327.1"
                     /translation="YNHALSKERSKVENIFAKVETFKMFSTTYRNHRKRFGLRMNLIA
                     GIINHELGF"
BASE COUNT          880 a          429 c          518 g          924 t
ORIGIN      
        1 gtcaaaaaga taatgtcaat ttttcaatcc ttttatgttg atgtcagtat tgaggaactg
       61 actttgactt taccaatcag ttttgtaaaa aggtttgagt atactcaaat gacttttcat
      121 aaggaatcat ttttattgat taaagaaaag agaaggggga gtttgagttc atttgttact
      181 caggctcgca ctatgggtga aaaagccaat atggatgttg ttttggtgtt ttcgaagtta
      241 tcagacagtg aaaaaaagca attacttcaa gctagagttc cgtttgtaga ctttaaggga
      301 aacctcttct tccctccatt gggactagta ctgaatgcga atgatactga agtccctaag
      361 gaattaacac ctagcgaaca attaacgtgg attgcctttt tattgacaaa aggtcaaaaa
      421 gtagtagatg ttgatttgct ttcacaagtc actggacttc caaactcaac aatttatagg
      481 tgtttgagga cttttaaagc tttatattgg ttaaacaagc aaaataagct ttacacatat
      541 acggtgtcaa agaaagaatt attcttaaaa tccgtgtcat gtttatttaa tcccatcaaa
      601 aaacggattt tattgccaga tggcgatata aagcagataa aatctgtttc taaccttcta
      661 tatggtggtg cttatgcttt gtcgcattca acttttttag ctgaaacgga tgaaaatact
      721 agctatgtca tatggcagag aaaattcaat cagttatcct tgccactttc tcagtatgtt
      781 ttaaaatgaa agatgctaga gatatggaaa tatcgtcctt ttgtatctga gttttggaat
      841 gattttaaaa ataatcatga taaacaattt gtagatccga tttctcttta tttgacctta
      901 aaagatgatg atgacccacg tatagaggaa gagagtgaag cactagaaaa tatgatatta
      961 cagtatctgg gagaagatga tgccagctaa tacgaaagtt atttttcaag aaatgtttgc
     1021 ggattttcag aactattatg ttctgattgg gggaactgct acctctatcg tattggattc
     1081 gcaaggattt aaaagtcgca caacaaaaga ttatgatatg gtcatcattg atgaagtaaa
     1141 aaataaggaa ttttatacta ccttgaatca ttttttagaa ttgggagagt atcaaggaag
     1201 tcagaaagat gagaaagcgc agctttttcg atttacaaca actaatcttg agtttccttc
     1261 tatgattgaa ctatttagta tcttaccaga atatccatta aagaaggacg gtcgagaaat
     1321 ttccttatat tttgaccaag atgctagttt atcagcctta ttattggatg aagattatta
     1381 taatatattg gtgcatgtaa aagaaaccat tcaggggtat tcggtattga gtaattgtgg
     1441 tctatactct tcgacaatct cttcaaacca cgtcagcttc catctacaac ctcaaaacag
     1501 tgttttgagc agcctgcggc tagcttccta gtttgctctt tgattttcat tgagtattaa
     1561 ttatttttaa ggctaaagct tggctggata tgagggaacg ctctgctaca ggtgctcaag
     1621 gtttaagtaa gtccattaaa aagcatttga atgaccttac ccgtttgaca gcttccttgc
     1681 taggagatga aaagttatcg gctataacat caagtagtgc ggtaaaagca gacatgcacc
     1741 gctttgtgat agaattagag cttgtgaagt caactattct tcaaaatgat gacatttcat
     1801 tagatcaaaa tgaaattttt gaaattctga aaaatttttt cgatggttaa aataattgta
     1861 gcgagatggc tatattgaat tcgtctatat ctggaaacta gaaaaaactt caatttcagg
     1921 agaaaatgaa gtcaatcttc ccacaatcaa acgtatagta tcaaggtttt tcaagacctg
     1981 atattatgcg ttttttgctt ttcaaaactt tttgcccagt ttttgttttt atcctctagt
     2041 cacttgattt gtttcaggtg gttttttagt atagtaaaat gaaacgagaa caggacaaat
     2101 tgatcaggac agtcaaatcg atttctaaca atgttttaga agcagaagtg tactattcta
     2161 gtttcaatct actatagtta aatctgcggt caagtctact ggtgaatcta tgattgtaat
     2221 actcttccaa aatctcatca accacgtcag tcttgccttg cagtctgtat cttactgacc
     2281 aagctagtga tggatttaga ataggtgatt tggagcgtcc tattggctag gaaatgctgc
     2341 tcatagtcct ttgctgaggc tagggtgttt caacattcaa cactcaactg gttgatctag
     2401 ttgataggaa gggagttact ataaaatact caggcttcca tcatattttt tgaaacgatt
     2461 gtgtaatcaa aatgtaccaa tattgtagta ttggtacaga agatgttgtg aatggataaa
     2521 tatatcataa ctgctatctc aaaaagattt catatgtctg tgcatatata atagacttcc
     2581 tgcaaaacta gaatcctagt tcatgattga taataccagc aatcaaattc attcgtaatc
     2641 caaagcgttt acgatgattt cgataggttg ttgaaaacat tttaaacgtt tctactttgg
     2701 caaagatgtt ctcaaccttg cttctctcct tagatagcgc atggttatag g
//
LOCUS       DAVHSY010000087         2295 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.089, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000087 DAVHSY010000000
VERSION     DAVHSY010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2295
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.089"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(1..447)
                     /locus_tag="VVR43_002032"
                     /pseudo
     CDS             complement(1..447)
                     /locus_tag="VVR43_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(392..574)
                     /locus_tag="VVR43_002033"
     CDS             complement(392..574)
                     /locus_tag="VVR43_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6150328.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            909..>2295
                     /gene="pcpA"
                     /locus_tag="VVR43_002034"
     CDS             909..>2295
                     /gene="pcpA"
                     /locus_tag="VVR43_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEU6150329.1"
                     /translation="MKKTTILSLTTVAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGV"
BASE COUNT          805 a          343 c          372 g          775 t
ORIGIN      
        1 tttttaccag aatcattcgc taattctttt tttagggcga ttgattttta cttccgtcgc
       61 atcaatcatt accgtgtcct cagagctgag aggagttctt gaaatcgtaa caccactttg
      121 aacaagagtt acttcaaccc attggctccg acggagtaag ttgctttcgt gaataccaaa
      181 atcagccgca atttcttcat aagtgcggta ttctcacaca tattgaagag tgcccataag
      241 aaggtcttct aggcttaatt taggttttcg tccacctttt gcgtgtttaa gttgataagc
      301 tgtttttaat acagctaaca tctctttaaa agtcgtgtgc tgaacaccaa caagacgctt
      361 aaatcgtgta tcagttaatt gtttacttgc ttcataattt cgcagggagt ctattgactc
      421 tttggtaggt gtcaatgttt ttttcatcta tcccgagaat tattttcccg ccatttgtat
      481 ttgcaaatgc tgagtaggtt tcccagaaag actctggaag attgttttta gcttttttgt
      541 attctaaatc aaccccttca aattttaagt ccatattttt cctttacatc tgttttttgt
      601 ggttctggta tttgttcaag ttgagtgata atatagcgaa ttgaatttcg agagttttta
      661 ctcagttaat ttctttttta acccacttta atttcttttt taacacgggt taaaaaagaa
      721 attaaagtgg gttaattttc cttgacttaa aatttaaaaa tgatatactg tgtttatgga
      781 gagatgacaa tttataaaat gtactactct attctactag ataatgattg aataaaactt
      841 tttataacaa cggctagcaa agttataatt ttatatctat tagaaaataa atatgtaagg
      901 aaatttaaat gaaaaaaact acaatattat cattaactac agttgcggtt attttagcag
      961 catatgtccc taatgaacca atcctagcag atactcctag ttcggaagta atcaaagaga
     1021 ctaaagttgg aagtattatt caacaaaata atatcaaata taaggttcta actgtagaag
     1081 gtaacatagg aactgttcaa gtgggtaatg gagttactcc tgtagagttt gaagctggtc
     1141 aagatggaaa accattcacg attcctacaa aaatcacagt aggtgataaa gtatttaccg
     1201 ttactgaagt agctagtcaa gcttttagtt attatccaga tgaaacaggt agaattgtct
     1261 actatcctag ctctattact atcccatcaa gcataaaaaa aatacaaaaa aaaggcttcc
     1321 atggaagtaa agctaaaact attatttttg acaaaggcag tcagctggag aaaattgaag
     1381 atagagcttt tgatttttct gaattagaag agattgaatt gcctgcatct ctagaatata
     1441 ttggaacaag tgcattttct tttagtcaaa aattgaaaaa gctaaccttt tcctcaagtt
     1501 caaaattaga attaatatca catgaggctt ttgctaattt atcaaattta gagaaactaa
     1561 cattaccaaa atcggttaaa acattaggaa gtaatctatt tagactcact actagcttaa
     1621 aacatgttga tgttgaagaa ggaaatgaat cgtttgcctc agttgatggt gttttgtttt
     1681 caaaagataa aactcaatta atttattatc caagtcaaaa aaatgacgaa agttataaaa
     1741 cgcctaagga gacaaaagaa cttgcatcat attcgtttaa taaaaattct tacttgaaaa
     1801 aactcgaatt gaatgaaggt ttagaaaaaa tcggtacttt tgcatttgcg gatgcgatta
     1861 aacttgaaga aattagctta ccaaatagtt tagaaactat tgaacgttta gccttttacg
     1921 gtaatttaga attaaaagaa cttatattac cagataatgt taaaaatttt ggtaaacacg
     1981 ttatgaacgg tttaccaaaa ttaaaaagtt taacaattgg taataatatc aactcattgc
     2041 cgtccttctt cctaagtggc gtcttagatt cattaaagga aattcatatt aagaataaaa
     2101 gtacagagtt ttctgtgaaa aaagatacat ttgcaattcc tgaaactgtt aagttctatg
     2161 taacatcaga acatataaaa gatgttctta aatcaaattt atctactagt aatgatatca
     2221 ttgttgaaaa agtagataat ataaaacaag aaactgatgt agctaaacct aaaaagaatt
     2281 ctaatcaggg agtag
//
LOCUS       DAVHSY010000088         2242 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.090, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000088 DAVHSY010000000
VERSION     DAVHSY010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2242
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.090"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            5..1759
                     /locus_tag="VVR43_002035"
     CDS             5..1759
                     /locus_tag="VVR43_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6150330.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     TLLALTIIGGLILGAMMGEQEFMKIYQEALSKLSAETVEYVRGMQVVKIFKANVESFK
                     IFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHSNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            1725..>2242
                     /locus_tag="VVR43_002036"
     CDS             1725..>2242
                     /locus_tag="VVR43_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6150331.1"
                     /translation="MNGGFQMKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAI
                     LLMIFAQEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTA
                     ENLSKLPLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMPAG
                     NVKMGLAVIIPS"
BASE COUNT          778 a          312 c          420 g          732 t
ORIGIN      
        1 gcttatgaag atttacaaaa aactatttgc ttatgtccaa gataagaaat atcttggggt
       61 tttggccata attttttctg ctatatctgc tctacttaca gtatatggat attatttaat
      121 ctacaaattt ctagataagt taataattaa ttcaaattta tccggtgcag agagcatagc
      181 attaaaatct gttattacac taacaagtgg agcgatattt tattttgtct caggaatgtt
      241 ttcacatatc ttgggattca ggcttgaaac aaatttaaga aaaaggggaa tcgatggtct
      301 ggaaaaagca agttttaggt tctttgactt aaatccatct ggtcaaataa gaaagatcat
      361 agatgataat gcagcacaaa ctcatcaggt ggtagctcac atgattcccg atagctctca
      421 ggcaatagtc acacctatac ttgtccttgt actaggcttt atagtaagta taagggttgg
      481 tataactttg cttgctctta ctataattgg tggcttaatt ttaggggcga tgatgggcga
      541 gcaagaattt atgaagatat accaagaagc tctatctaaa ctaagtgctg aaactgttga
      601 gtacgtgaga ggaatgcaag ttgtaaaaat atttaaagca aatgtagagt cttttaaaat
      661 cttttataag gcgataaaag attactcaaa gtatgcttat gattattccc tatcttgtaa
      721 aaggccttat gttttgtatc aatggttatt ttttggactg attgcaattt taattattcc
      781 tatagtttat tttatgacta gcttagctag cgcaaaggtg attttacttg agcttatcat
      841 gattttattt ttatcaggag ttctctttgt ttcattcatg agaatgatgt ggtactccat
      901 gtatatttct caaggaaatt atgcagtaga tactttagag gcgctttacg aagatatgca
      961 aaaagacaaa ttagtgcata gtaatgtcaa taattttaaa aactataata tagaatttga
     1021 gaatgttagc tttgcttata atgataaagc tgtcattgaa aatttatcct ttaatttaga
     1081 agaaggaaag tcctacgcac ttgtcggttc atctggatca ggcaaatcaa cagtagcaaa
     1141 acttatatca ggtttttaca atgttaataa aggaagcata aagataggcg ggatagcaat
     1201 aagtgaatat tctgacgaag ccttaattaa agccatttcc tttgtttttc aagattcaaa
     1261 attattcaag aagagcattt atgataatgt agctttagct aataaagatg cgacgaaaga
     1321 tgacgttatg agagccttaa aattagcagg atgcgattta atattagaca aattcccaga
     1381 aagagaaaat acaatcatag gctcaaaagg tgtttattta tccggtggag aaaaacaaag
     1441 aattgcaatt gctagagcaa ttttaaagga ttccaaaatt attattatgg atgaagcatc
     1501 agcatctatt gacccagata acgagtttga attgcaaaaa gcttttaaaa atcttatgaa
     1561 ggataaaaca gttatcatga ttgcacacag gctatctaca attaaagacc ttgatgaaat
     1621 tattgtcatg gatagtggaa aaattataga aagagggtct gacaaagaat taatgtcaaa
     1681 agatacaagg tataagagcc tgcaagagat gtttaacagt gcgaatgaat ggagggtttc
     1741 aaatgaaaga gttttataaa aaaagatttg ctcttacaga tggaggagca agaaatttaa
     1801 gtaaagcaac actggcttca tttttcgttt attgtataaa catgcttcct gccatattac
     1861 ttatgatttt tgctcaggaa gttttggaaa atatgggcaa aagcaatggc ttttatatag
     1921 tattctcagt tttgactttg atagcaatgt atattttgct ttctatcgaa tacgataaat
     1981 tatataacac aacctatcaa gaaagtgcag atttaagaat aaggacagcg gagaatttat
     2041 caaaattacc tctatcttac ttttctaaac atgacatttc cgacatttca caaacaatca
     2101 tggctgatat tgaaggcata gagcatgcaa tgagccactc aataccaaag gtgggcggca
     2161 tggtactgtt tttcccatta atatctgtaa tgatgccagc gggcaatgtc aagatgggtt
     2221 tagctgtaat tattccatct at
//
LOCUS       DAVHSY010000089         2191 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.091, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000089 DAVHSY010000000
VERSION     DAVHSY010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2191
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.091"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..952
                     /locus_tag="VVR43_002037"
     CDS             <1..952
                     /locus_tag="VVR43_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6150332.1"
                     /translation="NLNLTINEGEFFTFLGPSGCGKSTTLRALVGFLEPSQGQILVDN
                     QDITNLDPEKREIGIVFQSYALFPTMTVFDNIAFGLKVKKVSPEIIKAKVHEIAKKIN
                     ISDEQLNRNISELSGGQQQRVALARALVLEPKILCLDEPLSNLDAKLRVSLRKELKRL
                     QKELGITTLYVTHDQEEALTLSDRIAVFNNGFIEQVGTPYDIYNQSATQFVCDFIGSI
                     NKISQEVLKKLQGENKYFKETEGYIRLERVKLEKTSPQDLSITGVISDIEFNGVLIKY
                     KVDLSNSESIHIIEKNDGLSRHIIKEKVTMYINPRDIMQF"
     gene            964..>2191
                     /locus_tag="VVR43_002038"
     CDS             964..>2191
                     /locus_tag="VVR43_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU6150333.1"
                     /translation="MRKSLNWKDCLIRLGVLWLIFALIIYPNIELLSGVFYKNGSFTL
                     EAFNKIIHSQRAMSSIFNSFILAISMVFTVNIVGTLIVLLTEYWDIRGSKILKLGYMS
                     SLVYGGIVLATGYKFVYGANGLVTKTLSSIIPGLAPNWFQGFGAVLFIMTFACTSNHI
                     MFLTNAVRSVDYHTIEAAKNMGASPLKVFFSVVFPTFKPTLFALTILTFLTGLSAVSA
                     PLIVGGKDFQTINPLIISFAKTTSSRDLAALLAIMLGLATILLLTLLNHVEKGGNYVS
                     VSKTKASIKKQIISSPLWNTLAHIVAYVLFAIYMLPIVLIILYSFTDSLTIKTGTLDL
                     SKFTLANYANLFTDAQSFRPYLVSVVYAILAAVIATIIAIVISRIVHKNKSKFDKFFE
                     YGALIPWILPGTLIALG"
BASE COUNT          713 a          326 c          404 g          748 t
ORIGIN      
        1 taatctcaat ttaacaatca atgagggaga gtttttcaca tttttaggac caagtggttg
       61 tgggaaatca acaactcttc gtgcactagt tggatttttg gagccttcac aggggcaaat
      121 actagttgat aatcaagata ttacgaattt agatccggaa aaacgcgaaa ttggtattgt
      181 gtttcaaagt tatgcattat tcccaacaat gactgttttt gataatattg cttttggtct
      241 aaaagttaaa aaagtttctc ctgaaattat taaagctaaa gttcatgaaa ttgcgaaaaa
      301 aattaatatc tcagacgagc aactaaaccg aaatatttct gaattatcag ggggacaaca
      361 acagcgtgta gctttagcac gtgcattagt attagaacca aaaattcttt gtttggatga
      421 accgttatca aacctagatg ccaaactacg agtttcgttg agaaaagaat tgaaacgatt
      481 gcaaaaagaa ctaggaatca ctactcttta tgtcacacat gatcaagaag aagcattaac
      541 attatcagat aggattgctg tgtttaataa tggatttatt gagcaagttg gcacgccgta
      601 tgatatttat aatcaatccg caactcaatt tgtctgtgat tttattggct caatcaataa
      661 aattagccaa gaagttctta aaaaattaca aggcgagaat aaatacttta aagaaactga
      721 aggatacata cgcttagagc gtgttaagtt agagaaaact tcacctcaag atttatctat
      781 aacaggggta attagtgata ttgagtttaa tggtgtactt attaagtata aagtagactt
      841 gtcgaatagt gaaagtattc atattatcga aaagaatgat ggactatcac gtcatataat
      901 caaagaaaaa gtcactatgt acattaatcc gcgtgatata atgcaatttt aaggagattg
      961 tgcatgagaa agagtctaaa ctggaaagat tgtctcataa gattaggagt tttatggcta
     1021 atctttgccc tgattattta tccaaatatt gaacttttgt ctggagtgtt ttataaaaat
     1081 ggttcattta ctctagaggc attcaataag attatacact ctcagagagc gatgagtagt
     1141 atatttaata gctttatttt ggcgatttca atggtcttta ctgtaaatat tgttgggaca
     1201 ttgattgttc tactcacaga gtactgggat attaggggtt caaaaatact taaattaggt
     1261 tatatgagct ctctagtata tggaggaatt gtattagcga caggatataa atttgtttat
     1321 ggcgctaatg gtcttgtaac taaaacgctc tcaagtataa ttccaggtct tgcccctaac
     1381 tggtttcaag gatttggtgc agtattgttt attatgacat ttgcttgtac ctcaaatcac
     1441 ataatgtttt taacaaatgc agttcgtagt gttgattatc atacaattga ggcagctaaa
     1501 aatatgggtg caagtccttt aaaagttttc tttagtgtgg tttttccaac ttttaaacct
     1561 acgttatttg ccttaaccat cttaactttt ttgacaggtc tttcagcagt ttctgctcct
     1621 ttgatagtag gggggaaaga ttttcaaact attaacccat tgattatcag tttcgctaaa
     1681 actacaagtt cgagagattt agcagcttta ctagctatca tgttaggttt agcaactatt
     1741 ctattattga cacttttgaa tcatgtcgaa aaaggaggta attatgtatc tgtttcgaaa
     1801 accaaggcta gtattaagaa gcagataatt tcttctccat tatggaatac tcttgctcac
     1861 attgttgcgt atgtattgtt tgcaatctat atgttaccaa tagttttgat aattctatac
     1921 tcgtttacag actcgttgac gatcaagacg ggaactttag atctatctaa atttacgtta
     1981 gcgaactatg ctaatttatt tacagatgct caatcatttc gtccttacct agtcagcgtt
     2041 gtttatgcaa ttttagctgc ggtaattgct acaattatag caatagtaat ttcacgtatt
     2101 gtacataaaa acaagagtaa gttcgataaa ttctttgagt atggtgcact gataccatgg
     2161 atattgccag gtacattgat tgcactagga t
//
LOCUS       DAVHSY010000090         2188 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.092, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000090 DAVHSY010000000
VERSION     DAVHSY010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2188
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.092"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            9..1292
                     /locus_tag="VVR43_002039"
     CDS             9..1292
                     /locus_tag="VVR43_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6150334.1"
                     /translation="MVEIVRGGSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKE
                     KIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLF
                     YILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLAEQQRIIEAIESALEKVDE
                     YAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFE
                     EGKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIP
                     IYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIY
                     HENKNPYAWAVADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELL
                     TKTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            1349..2146
                     /gene="psrA"
                     /locus_tag="VVR43_002040"
     CDS             1349..2146
                     /gene="psrA"
                     /locus_tag="VVR43_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEU6150335.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT          788 a          309 c          390 g          701 t
ORIGIN      
        1 tttctacatt ggttgaaatt gtcagaggtg gctctccacg accaatcaaa gattatctta
       61 cttctgaagt agatggaata aattggataa aaataggtga tactgaaaag ggtgaaaagt
      121 atataaataa tgttaaagaa aaaatcaaaa aatcagggct taacaaaact agatttgtaa
      181 aaaaaggtac atttttgtta actaattcta tgagttttgg tagaccttat attttgaatg
      241 ttgatggtgc aatacacgat ggatggttgg ctatttcgaa ctatgaaaac tcattaaata
      301 aagattacct attctatatt ctttcatcaa atgtagttta ttctcaattt ctatctctaa
      361 ttagtggagc tgttgtgaaa aacttgaata gtgataaagt tgcttctatt cttatccctc
      421 tccctccgct agctgaacaa caacgcataa tagaagcaat cgaatcagct ttagaaaaag
      481 tagatgaata tgctgaaagt tataatagac tagaacagct agataaagaa tttccagata
      541 aactaaaaaa atctattctt caatatgcta tgcaaggaaa attagttgaa caagacccaa
      601 atgatgaatc agtcgaagtt ttacttgaaa aaatacgagc agaaaaacaa aaactctttg
      661 aagaaggcaa gattaaaaag aaagatttgg acatttctat tgtttcccaa ggagatgata
      721 actcttatta tgaggaagta ccttgtgaaa taccagaaag ttgggaatgg gtgaggttaa
      781 acgatataac ctcctacatt caaagaggga agtctccaaa atattcaaat attcctatat
      841 accctgtgat tgctcagaaa tgtaatcaat ggtctggctt ttctattgac ttagcaagat
      901 ttattgatcc cgaaacagtt catagttacc agaaagaaag attactaagg gatggtgatt
      961 taatgtggaa ttcaacaggt ctaggtacgt taggacgatt agctatttac catgaaaata
     1021 aaaatcctta tgcctgggct gttgcagata gccatgttac agttataaga gtcttatcgg
     1081 gggttattaa ttgccatttc atctataatt ttctttcctc tcctattgtt cagtcagtta
     1141 ttgaagaaaa agcgtcgggt agtacaaaac aaaaagaatt attaacgaaa actataaaag
     1201 aatatttaat ccccctccca ccccttcctg aacaatccag aatcgttgat aaaatcgaac
     1261 aatttttcgc ccatattgac gcactaattt agtataatag ttttacgtgc ggtggaattt
     1321 ctatcaaaca taagatagga gttttacgtt gaaagatttt gaattacatt tgaagaaagc
     1381 tggtttagct gaaaatactg tgcgttcgta cctttatggt gttcgatttt tcttggagaa
     1441 ttacgaactc aaaatggaag atttatttga atacaaagga tatttattag acaattttaa
     1501 acctaaaact gtcaatttgc gactacaagg agtaaataaa tatctggctt ttattggtca
     1561 tgatgatttg aaattaaaat ttgtcaaagt acagcaaaaa ccgtttttag aagatgtcat
     1621 tagccatgct gattaccttt ttcttaaacg tagtttgaaa aaagatggta ttttaaaatg
     1681 gcattttgtc gtttggtttt taggtgcaac tggggctcgt gtaagtgaac ttattaaact
     1741 aaaagtagag catgtagaaa tcggttattt tgacatttac tcaaaaggtg gtaaaattcg
     1801 tagactgtac attcctaaaa aattaagaaa tagttgtctt agttggttag aatcagaaaa
     1861 tcgccgaagt ggttatttat ttttgaataa atttaacgaa ccaattacag caagaggagt
     1921 tgctcaacag ttaaaaaatt atgctgataa atacaaaatg aatcctaaag taatttaccc
     1981 tcattctttt aggcatttat ttgctaagaa ttttttagcg aagtataatg atattgcctt
     2041 gcttgcagat ttgatgggac acgaaagtat agaaactact cgaatttatc taaggaaaac
     2101 agctactgaa caacaaaata ttgtagataa aattgttaat tggtaaaaaa taacaggtgg
     2161 tcaaactgac tacctgctat ttttgtga
//
LOCUS       DAVHSY010000091         2086 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.093, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000091 DAVHSY010000000
VERSION     DAVHSY010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2086
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.093"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            22..843
                     /locus_tag="VVR43_002041"
     CDS             22..843
                     /locus_tag="VVR43_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU6150336.1"
                     /translation="MEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIGVTSS
                     SSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIGFQAV
                     TRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFNKRLE
                     IIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALNIGKK
                     RSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRNI"
     gene            843..1637
                     /locus_tag="VVR43_002042"
     CDS             843..1637
                     /locus_tag="VVR43_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6150337.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
BASE COUNT          777 a          323 c          347 g          639 t
ORIGIN      
        1 cctggagcta gtttttcgat tatggaaatt agattaccaa aattattagc aggaattata
       61 gctggctggt cttttggatt ggcaggattt atctttcaaa ctatgttaag aaatcctctt
      121 gcaagtcctg atataatcgg tgtcacaagt tcttcatcta ttgcagcggt cttttgcata
      181 ttggtattaa aaacaaatag tttaactact ggaattattt caataacttg tggactaaca
      241 tcatctttaa tattattttt actagctaaa aaagatggtt tttcagcagc aagactgata
      301 atattaggta ttggttttca agctgtcaca agagcaggca cctcattttt attgttgaaa
      361 gtagcaagat atgaattaca agaagttatg agatggctca gtggctcttt atcttttaca
      421 aagttagatg acatacctct tgttctaata gtaagtatta ttgctactat attagtttta
      481 ttttttaata aaagactaga aattattgaa cttggtgaag aaatagcaat cggacttgga
      541 gcaaatcccg agctttcaag gcttgtttta attttttgcg ctgtatcttt aactgctttt
      601 tctacttcaa ttacaggacc aatagcttgt atatcttttt tagctggtcc catagcctta
      661 aatattggca agaaaagaag cccaatatta gctggattgg ttggaatttt actagttttg
      721 ttatcagaca tattctctca aaatatttta ccagctagat atccagtagg tgttgtaact
      781 ggcttgttag gttcaccata cttaatatac ttactaataa aaatgaacag gaggaatata
      841 taatgaaagg tctgtggtca aataatctta cctgcggtta tgatgaaaaa ataatcttgg
      901 aaaatataaa tataaaaata cctgaagaaa aaatatcagt tattattggg tcaaatggtt
      961 gtgggaaatc aacactcatt aaaaccttgt ctcgacttat aaagccatta gagggagaag
     1021 tattgctcga taataaatca attaattctt ataaagaaaa agatttagca aaacacatag
     1081 ctatattacc tcaatctcca ataatccctg aatcaataac agtagctgat cttgtaagcc
     1141 gtggtcgttt cccctacaga aagcctttta agagtcttgg aaaagatgac cttgaaataa
     1201 taaacagatc aatggttaag gccaatgttg aagatctagc aaataaccta gttgaagaac
     1261 tttctggggg tcaaaggcaa agagtatgga tagctctagc cctagcccaa gatacaagta
     1321 tcctactttt agatgagcca actacttact tggatatctc atatcaaata gaactattag
     1381 acctcttgac tgatctaaac caaaaatata agacaaccat ttgcatgatt ttgcacgata
     1441 taaatctaac agcaagatac gctgattacc tatttgcaat taaagaaggt aaacttgttg
     1501 cagagggaaa gcctgaagat atactaaatg ataaactagt taaagatatc tttaatcttg
     1561 aagcaaaaat tatacgtgac cctatttcca attcgcctct aatgattcct attggcaagc
     1621 accatgttag ctcttaataa ttgaatattg gaattcattt aaaagtcgca aattttgaac
     1681 tgaccctcaa aagttaggcc aaaaaactaa ctaaaggagg tcagtttttt aatggcaaat
     1741 acagcacaga atttaagata aaattagtaa aagaatatca tgaatgaaaa ataggatata
     1801 gagaataaca gcaatattaa aaagatcagg actgataata aacaaaaaga aagtacaacg
     1861 actagttcaa aagctaaaac ttcaagtaaa aagttattca agaaaatcta gaaaatactc
     1921 atcctacaaa ggacaggtag gaaaaatatc agacaacaaa ataaaaagaa atatttatta
     1981 ccgaaaaaaa ggggaaatcg agtcaagtac caacaggctc atctattcca aaaagatatt
     2041 tactcgatgg aaaaactcct agaattagtg ctacaaatat tgacaa
//
LOCUS       DAVHSY010000092         2064 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.094, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000092 DAVHSY010000000
VERSION     DAVHSY010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2064
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.094"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            54..1079
                     /locus_tag="VVR43_002043"
     CDS             54..1079
                     /locus_tag="VVR43_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU6150338.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1069..>2064
                     /locus_tag="VVR43_002044"
     CDS             1069..>2064
                     /locus_tag="VVR43_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU6150339.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIALSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRG"
BASE COUNT          725 a          293 c          369 g          677 t
ORIGIN      
        1 caatgataat tattatcgat acaatagact tgaaatatgt ttaaggagtt tttatgaaaa
       61 acaaattttt tctaatagct attttagcta tgtgtatagt ttttagcgct tgttcttcta
      121 attctgttaa aaatgaagaa aatacttcta aagagcatgc gcctgataaa atagttttag
      181 atcatgcttt cggtcaaact atattagata aaaaacctga aagagttgca actattgctt
      241 ggggaaatca tgatgtagca ttagctttag gaatagttcc tgttggattt tcaaaagcaa
      301 attacggtgt aagtgctgat aaaggagttt taccatggac agaagaaaaa atcaaagaac
      361 taaatggtaa agctaaccta tttgacgatt tggatggact taactttgaa gcaatatcaa
      421 attctaaacc agatgttatc ttagcaggtt attctggtat aactaaagaa gattatgaca
      481 ctctatcaaa aattgctcct gtagcagcat acaaatctaa accttggcaa actttatgga
      541 gagatatgat taaaattgat tcaaaagcct taggtatgga aaaagaaggt gatgagttaa
      601 tcaaaaatac tgaagctcgt atatccaaag aattagaaaa acatccagaa atcaaaggaa
      661 aaatcaaagg aaaaaaagta ttatttacta tgattaatgc tgcagataca tcaaaattct
      721 ggatttatac tagcaaagat ccaagagcaa attatttaac agatttaggt ctagttttcc
      781 ctgaatcatt aaaagaattt gagagtgaag atagttttgc aaaggaaatt tctgcagaag
      841 aagcaaataa gataaatgat gctgatgtaa tcataactta tggtgatgat aaaactcttg
      901 aagctttaca aaaagatcct cttttaggta aaataaatgc aattaaaaat ggtgccgttg
      961 ctgtaattcc agataataca ccgttagcag cctcatgcac tccaacacca ctttcaataa
     1021 actatactat tgaagaatac ctaaatcttt taggaaatgc atgcaaaaat gcgaaataaa
     1081 aaacaaataa acctaggcat aatttttgta atctgcctag gtcttcttat tacaatattt
     1141 ttgtcattaa agcttggaac aaaagaaatt aatatcagag attttttagc agcttttgga
     1201 atgggtaata caaatgatga ttttattaaa tcaattatat ataaaagaat acctagaact
     1261 atttttgcaa ttttagcagg ttctagtctt gccataagcg gtgtgttgat gcaatcagtt
     1321 actagaaacc caatagctga tccaggtata ctcggtataa acacaggagc aagtcttagt
     1381 gtagtaattg ctctttcttt tttaggaatt tcatcaagca taagccatat aagttttgca
     1441 atcattggtg gcttagtaag tgcaattttt gtatacgcga ttgctgtaag cggaaaagca
     1501 ggccttaccc ctataaaact agccttatca ggaacttgtg ttagtatggc tttaagcagt
     1561 tttgtaagtt ttttaatttt accgaataat aacgtcttag acaaatttag attttggcaa
     1621 ataggtagcc ttggagcagc tacattatct tctatatcta cactactacc ttttataatt
     1681 ttaggtcact tgatagctat atttatttca tcagatttaa acgctttagc tatgggtgat
     1741 gaaatggctg ttggtcttgg agttaatgtt aataggataa gatcacttgc aataattgca
     1801 agtgtgcttt tatgttcaag tattactgca attggtggac ctattggctt cgtaggtctt
     1861 atagttcctc acttttgtgg cttatttata agcaaagata tacgcacaat gaccatttct
     1921 tcatctttta taggtgcaga gctcttgctt atatgtgata taatcggccg tatgttaggt
     1981 aaaccaggtg aaattgaagt agggataatt actgcaataa tcgggggtcc agtacttatt
     2041 tatgtaacta tgaaaaatag aggg
//
LOCUS       DAVHSY010000093         2048 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.095, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000093 DAVHSY010000000
VERSION     DAVHSY010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2048
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.095"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            1..929
                     /locus_tag="VVR43_002045"
                     /pseudo
     CDS             1..929
                     /locus_tag="VVR43_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1132..>2048)
                     /locus_tag="VVR43_002046"
     CDS             complement(1132..>2048)
                     /locus_tag="VVR43_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HEU6150340.1"
                     /translation="KAEATRLEKIKTDRKKAEEAKRKAAEEDKVKEKPAEQPQPAPAP
                     KPEKPAPAPKPENPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQPS
                     TPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNA
                     NGDMATGWLQNNGSWYYLNANGSMATGWLQYNGSWYYLNANGDMATGWLQNNGSWYYL
                     NANGSMATGWLQNNGSWYYLNANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKW
                     YYVNGSGALAVNTTVDSYRVNANGEWVN"
BASE COUNT          529 a          438 c          382 g          699 t
ORIGIN      
        1 ctttccatct caacttcaac tgttattcgt aagctcaatg attttcactt taaacatgat
       61 ttttcgcgtc ttcctgagat tatgtcttgg gatgagtatg cttttacaaa gggaaagatg
      121 agcttcattg cgcaagattt taacaatctc aatatcatca ctgttcttga aggtagaaca
      181 caagctgtca tccgagatca ctttcttaaa tatgatagag ccgtccgatg tcgcgtcaaa
      241 atcattacta tggatatgtt tagcccttac tatgacttag ctaaacagct tcgctttcaa
      301 atttctaggc tcaggctgaa acagtctcct agactgtttc actcccgaat gctaaaatcg
      361 ttcttgatcg ctttcatatt gtacaacatc ttagccgtgc tatgagtcgt gtgcgtgttc
      421 aaatcatgaa tcagtttcat cgaaaatccc atgaatacaa ggctatcaag cgctactgga
      481 agctcataca acaggatagt cgtaaactca gcgataaaca tttttatcgc cctacttttc
      541 gtatgcattt aaccaataaa gagattttag acaagctttt gagctattca caagacttga
      601 aacatcacta tcagctctat caactcttgc tgtttcactt tcagaataag gaaccggaga
      661 aatttttcgg actcattgag gacaatctaa agcaggttca tcctcttttt cagactgtct
      721 ttaaaacctt tctaaaggac aaagagaaaa tcgtcaacgc ccttcaacta ccctattcaa
      781 acgccaaatt ggaagcgacc aataatctca tcaaacttat caagcgcaat gcctttggtt
      841 ttcggaactt tgaaaacttc aaaaaacgga ttttcatcgc tctgaacatc aaaaaagaaa
      901 ggacgaaatt tgtcctttct caagcttagc tgacttcaac ccactacagt tgacaaagag
      961 tcaaaaaaac tccgtagtct ctagcgctat aaatccggct agagattaca gagttatttt
     1021 tttatctaaa cttcctacaa gggtatatta tctactgaaa ggatatggta tttgtaggga
     1081 atactttaaa gagttcttac aggaagtcag tattaactag ttatattagg tttagtttac
     1141 ccattcacca ttggcattga ctctatagct atctacagtt gtgttgactg caagggcacc
     1201 tgagccattg acatagtacc atttatctga tactttgaac cattggcttg ctttcatagc
     1261 acctgatgct tcaagatagt accaggtatc tccatctttc acccaatctg tcgccattga
     1321 accattagcg tttaggtagt accatgagcc attgttttgg agccatcctg tcgccattga
     1381 accattagcg tttaggtagt accatgagcc attgttttgg agccatcctg tcgccatatc
     1441 accattagcg tttaggtagt accatgagcc attgtattgg agccatcctg tcgccattga
     1501 accattagcg tttaggtagt accatgaacc attgttttgg agccatcctg tcgccatatc
     1561 accattagcg tttaggtagt accatgaacc attgttttgg agccatcctg ttgccattga
     1621 accattagcg tttagatagt accatgagcc attgttttgg agccatcctg tcgccattga
     1681 accatcagta ttgtagaagt accacatacc gttttcttgt ttccagcctg tttttggagt
     1741 agatggttgt gctggttttt cagtttttgg cggttgctgt tgagtcaagc gattatattc
     1801 ttcttctgat ctacgagcat agtcttcttc agcttgttga tcagctggtt tttctgcttt
     1861 tggttgttca gctggattct ctggttttgg agctggagct ggtttttctg gttttggagc
     1921 cggcgctggt tgtggttgtt cagctggttt ttctttaact ttatcttctt ctgctgcttt
     1981 tcgtttagct tcttctgctt ttttacgatc tgtcttgatt ttttctaacc ttgtagcctc
     2041 agcttttt
//
LOCUS       DAVHSY010000094         1966 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.096, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000094 DAVHSY010000000
VERSION     DAVHSY010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1966
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.096"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            44..1168
                     /locus_tag="VVR43_002047"
     CDS             44..1168
                     /locus_tag="VVR43_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6150341.1"
                     /translation="MGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNFLSVTFSSIT
                     GDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKKVFFALLLLH
                     IVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIALKQKKFEQK
                     HLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEVLVKANHKLR
                     SDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIELLDLVRIMS
                     VLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFALGFSTKGRN
                     RGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            1165..1917
                     /locus_tag="VVR43_002048"
     CDS             1165..1917
                     /locus_tag="VVR43_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6150342.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
BASE COUNT          675 a          269 c          364 g          658 t
ORIGIN      
        1 tctatattta gatgggttag ggattgaaag atttttattt cctttgggat tatattccta
       61 ttttcgatgg atgaaacagt atgagaggga tagaggacta ttcctaagtt tactactatc
      121 tcttttatat gagagcactc ataactttct gtccgtaact ttctcctcta taacaggaga
      181 taattttgtt ttacaatatc atttcccatt ctttttcgtt gtgacggtgt taacctattt
      241 tgttacatta aaaatcattt actatttcca tttggaacta gcctattttg acgaggacta
      301 cctttatcct ttcttgaaaa aagtattttt tgctttacta ttgctacata ttgtatcttt
      361 cgtttcagat atggtaagta cgattaaaca tttgaatagt tttggaagta ttttgtcatc
      421 tattgtcttt atctctctcc ttttgacctt ctttgcaatg aattctcata aagttcaaat
      481 ggagaaagag attgctttga agcagaagaa atttgaacag aaacatttac agaattacac
      541 agatgaaatt gttggtctgt ataatgaaat ccgtggtttt cgacatgatt atgctggaat
      601 gcttgtcagc atgcagatgg caattgacag tggtaattta caggaaattg acagaattta
      661 caatgaagtt ttagtcaaag caaatcataa attgcgttca gataagtaca cttactttga
      721 tttgaacaac atagaagact cagctttacg aagtttggtt gctcagtcaa ttgtctatgc
      781 tcgaaataat ggtgtagagt ttacactgga agtaaaagat acgattacca agcttccaat
      841 tgaactattg gatttggttc gtatcatgag cgttttattg aataatgctg tcgaaggatc
      901 ggctgatagc tataaaaagc agatggaagt agcagttatt aagatggaaa ctgaaacagt
      961 tattgtgatt cagaattcat gtaaaatgac gatgactcct tcaggagatc tatttgcctt
     1021 aggattctcc actaagggaa gaaatcgcgg agtcggatta aataatgtga aagaactact
     1081 agataagtac aacaatatta ttttagaaac agagatggaa ggcagtacat ttagacaaat
     1141 cattagattt aagagggaat ttgaatgaaa gttttaattt tagaagatgt tattgaacat
     1201 caagtgagac tagagagaat attggatgaa atttcgaaag aatcgaatat tccaatatca
     1261 tacaagacaa cgggaaaagt ccgtgaattt gaagaataca ttgaaaatga tgaagtaaat
     1321 cagctttatt tcctagatat cgatattcat ggaattgaga aaaagggatt tgaagtggct
     1381 cagctcattc gtcattacaa tccttacgct attatcgtct ttatcactag tcgatcagag
     1441 tttgcgactc taacctataa ataccaggta tcagccctag attttgttga taaggatatc
     1501 aatgatgaga tgtttaagaa gagaattgag caaaatatct tctacacgaa gagtatgtta
     1561 cttgaaaatg aagatgttgt agattatttc gactacaatt acaagggaaa tgatttaaaa
     1621 attccttacc atgatatttt gtatattgaa acaacagggg tctctcataa attgcgcatt
     1681 attggtaaga attttgcaaa agagttttat ggtaccatga cagatattca ggaaaaggac
     1741 aaacatactc agcgatttta ttctcctcac aagtcatttt tggtaaatat aggcaatatc
     1801 agagaaattg atcgaaaaaa cttagaaatt gttttctatg aagaccatcg ttgtcctatt
     1861 tcaagattaa aaattagaaa attaaaagat attttagaga aaaaatctca aaagtgattg
     1921 acaattagca agaaattgat ataatggtta tatctgctac agatag
//
LOCUS       DAVHSY010000095         1810 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.097, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000095 DAVHSY010000000
VERSION     DAVHSY010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1810
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.097"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            186..719
                     /locus_tag="VVR43_002049"
     CDS             186..719
                     /locus_tag="VVR43_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEU6150343.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKEKVKPNKKDMTREI"
     gene            846..1568
                     /locus_tag="VVR43_002050"
     CDS             846..1568
                     /locus_tag="VVR43_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEU6150344.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIDIEKDIEIDKEREIDKKSTP
                     IFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEE
                     DKDKLRQKGLNKKMNYDVGESL"
BASE COUNT          890 a          240 c          304 g          376 t
ORIGIN      
        1 aggtggaaag gtagtgtaag ctatttttaa aagtataaaa ggtacaaaga cctaagaaat
       61 atataaaaac atcaaaataa agtattccac caccaagaac aataaaataa aaacaagcaa
      121 agggaagtat agaaaaatta aaacctatac ttcccttttt taattcaaac aaaggagaga
      181 aaagcatgat aaacgaagaa ataagcaagg aagcaggtca agcagcacaa accataatat
      241 catacacaat aaaggcaaca aaagaatcaa tcaatttaga aaaagaaata agaaaaaaga
      301 tgaatgaaac tttagaaaaa gcaaatggaa acttaaaaag tcttatgggc gatgaaatga
      361 aaataaaaga cctctacaag aaaggacaac tagaaaatat aagcatagat caaatcgacc
      421 tcaaagactt aaaaaaagaa ctaaacaaac ttggagtaag tttctcagta atgaaaaaca
      481 aagaaagcaa aaactatgaa atattcttcc aagccaaaga cataaaagta atggaatatg
      541 cctttaagca agtcatagcc aaggaaaata aaaaagaaaa agaaagtatc ctaaaacaaa
      601 taaagaaata caaagaccta tccaaaaaca aagataagac aaaagaaaaa ggaaaaagga
      661 aagtaaaaga aaaagaaaaa gtaaaaccaa acaaaaaaga tatgaccaga gaaatctaaa
      721 gggagtaacg aaaagttaca cccttaaata accataataa caagacttcc gaaaaacaga
      781 agtccagaat tccgaaaatc ggaaatcaag aatttcgatt atcgaaaatc aagaaaggag
      841 cagatatggc aacaaacaaa agatactatt ggataaaatt aaaagaagaa tttttcacag
      901 acaaaaggat aaaaaggtta aggagaatat ctggaggaga tacctatacg ataatctacc
      961 taaaacttct actactaagc ctaaaagatg agggcaaact ctattatgac ggagtagaaa
     1021 gtgattttat aaaggagtta gcactaacca tagatgaaac agacgatgat gtaatggtaa
     1081 cagtaaatta tttaatcaat caaggcttat tagaagttgt aacagaaaat gatgaatact
     1141 acctaactga aataccaaac ttaatcggat cagaaacagc ctgggcagag aaaaaaagaa
     1201 gatacagaca aaataaacag aggacattgt ccttaatgag tccaacccat gtccgacaag
     1261 agatagatat agagaaagat atagagatag ataaagagag agagatagat aaaaagtcca
     1321 cccccatttt ttatggagaa ttcaaaaatg taaggttaag caaagaagaa tataaaaatc
     1381 taaaagaaaa attaaactca cacacagata taatgataaa taaactatcc agatacatgg
     1441 aaagcagtgg taagacctat caaaaccact atgtgacaat cttaaaatgg tatgaagaag
     1501 ataaagacaa actaagacag aaaggtttaa ataaaaaaat gaattatgat gtaggagaat
     1561 ctttatagat aaaaagaggt ggaaaggcac tattaaagac tttaagtcta aaaaggtatc
     1621 aaagtatgcc agagataaaa aaatataaat atgacacttt aaaggcgatt agaaaattaa
     1681 agaaatgcta gaagactttt agatgacagt taccaagagg atctaatttt cactgctact
     1741 tatgcagtgg gaattggacc tttttatata agcaaattct atttcaaaat tggttaccaa
     1801 gaaagacttc
//
LOCUS       DAVHSY010000096         1528 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.098, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000096 DAVHSY010000000
VERSION     DAVHSY010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1528
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.098"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            13..306
                     /locus_tag="VVR43_002051"
     CDS             13..306
                     /locus_tag="VVR43_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEU6150345.1"
                     /translation="MEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNKRLIEKGAV
                     FESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKDEIT"
     gene            620..>1528
                     /locus_tag="VVR43_002052"
     CDS             620..>1528
                     /locus_tag="VVR43_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEU6150346.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEKWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDIERDKVID"
BASE COUNT          723 a          185 c          272 g          348 t
ORIGIN      
        1 aaaagattaa gtattgaaga acagattgaa aagaaagaag aaagcattaa gcaattacaa
       61 aatcaaaaaa gacagttgaa gaaaaaactt aatgaacaag aaagaaaagc aagaaacaaa
      121 agacttatag aaaaaggtgc agtgtttgaa agtatttttg aagaaagtat tgatttaaca
      181 aaagatgaat tttataagtt aataaaaacg ttaaatgatg aagaaataag attaaacata
      241 atggaaattt tagaagaaag aatagatgat aatgtagaaa aatcatctaa agatgaaata
      301 acataattgt cccttggtta caagggcgca attatacacc ctaaagggtg cttgcgtcct
      361 gcggagtcaa acccttgcag ggagcaacaa ccattcgctt tttaaaagtc aagggtaaat
      421 aaactcgcta aggctcgccc ttgactttta aaatttgaaa tgaaagtaac aattaagccg
      481 acatactgaa acaacaaaaa ttaattcagt agtcggcttt tttaattcta tcatttcaaa
      541 acgctcattc acaaagagga tataaaaaaa ctattaagcc tccacctaaa acaacaaaga
      601 aagaaaggaa gtgataaaaa tggcagacag ttttcatttt tcagtaaaca taatatcaag
      661 aggaaaaggc aaaagtgcag tagcaagtgc agcatatata agtggagaaa aaataaaaaa
      721 tgaatgggac ggagtaaccc atgactacac aagaaaagaa aaaatattag taaaaaatat
      781 aatattgcct gatcatatac caaaagaatt taatgatagg tctaccttat ggaataaagt
      841 agaaatggca gaaaaaaatt ctaatgcaca actagcaaga caattcataa taggactacc
      901 aaaagagtta tctttaagtg aaaataaaaa cctggttgaa agatatataa aagaaaattt
      961 aacatcacaa ggaatgatag tagattatgc aattcatgat gagagtcaag ataaaaatgg
     1021 aaatatccat tgtcatataa tgaccataat gcgaccaata aacgaaaaag gagagttctt
     1081 agccaagtca aaaaaagaat atatcctaga tgaaaaagga gaaaaagtat taaacaaaaa
     1141 tggaaaacca aagacaagaa aagtagaact aacaacctgg aacgatacag gcaatgtaga
     1201 aaaatggaga gaaaattttt cagatctttg taacaaatat ttagaaagag caggagcaga
     1261 aaaaagagta gaccatagga gttttaaaag acaaaattca gattatctac cgacaatcca
     1321 tttaggatca gcagcaagtg caatggaaag aaagggaata gaaactgaca agggaaacta
     1381 taatagagaa ataagaaaat ataatcaact tgtaaaaaca ataaaagaag agataaaaac
     1441 attaaagggt tggataggaa atttattaga taacttatct actgcttatg aaaaatttaa
     1501 ggatatcgaa agagataagg taatagac
//
LOCUS       DAVHSY010000097         1416 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.099, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000097 DAVHSY010000000
VERSION     DAVHSY010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1416
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.099"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            252..592
                     /gene="tnpB"
                     /locus_tag="VVR43_002053"
                     /pseudo
     CDS             252..592
                     /gene="tnpB"
                     /locus_tag="VVR43_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(625..1416)
                     /locus_tag="VVR43_002054"
                     /pseudo
     CDS             complement(625..1416)
                     /locus_tag="VVR43_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          428 a          289 c          255 g          444 t
ORIGIN      
        1 ttaatttcat aataaaaaca ccccaaaaag ttagattttt tctgtctaac tttttggggg
       61 gcagtacact acacctacta ttatacgttt ttatcatttt gaaatctact gctaatcaat
      121 gaagaagcaa agatcaaact aggcagctag ttacaagtta cgtaagcgcg tcataacaag
      181 gtatctatcc taattcccca acttccagta tactagataa aaaataatta tcggaggaaa
      241 ggtattgtac tatgataatt caactaagtg atttaggtca agttcacctt gtttgtagca
      301 agatagatat gaggcaggga atagactcat tagcctatgt agttaaaacc cactttgaat
      361 tggatccttt ctccggtcaa gtctttctct tttgtggtgg acgtaaagac cgctttaaag
      421 ccctttactg ggatggtcaa ggattttggc tactatataa acgctttgag aacggcagac
      481 tgacttggcc cagtacagaa aaggatgtca aagctctcac acctgaacaa gtagactggc
      541 ttatgaaggg cttttctatc actccaaaaa taaatccatc agaaagtcgt gatttctatt
      601 gaaatgagga ctttcttttt atactcatct gctttcaaaa agcattctag tccatctccg
      661 attaacgatg ggctttatca cctccttctc cagtccttgt atgatatctt aaagttgatt
      721 catgacatct tccaaagttt gaaaggcttt atttttaaat ccacgtttac gaatctcttt
      781 ccacacttgt tcaatggggt tcatctctgg tgtgtacgga ggaataaatg caaagccaat
      841 attagtcgga atctttaagg tacttgattt atgccatata gcattgtcca taacgaataa
      901 aagataatca tctggataag cttgtgaaag ctcttctaaa aagacgttca tccactcagt
      961 attacatcca ccagctatta agaaaaatga ttcgcctgta tgggtccata acaatagcga
     1021 aattctcgta tatagtgact atggacatgt ggacctactc ctattggaga ccaacaagat
     1081 cccagtttac tgattctacc gaagccagcc tcatcttggt acatcaagcg aaccttatga
     1141 aaacgtctac tggttttaaa acgctttctt ttcttcttga attgagattt tatttttaga
     1201 cgcgacaatg gtttgagcgt ctgctttctt aggatgttct ggacgtggca taatatttcg
     1261 ccaaccatgg cgcttcaaca gttgatagaa ggcatcacgt gtgtaggaac gacctaactc
     1321 ctttttataa gcctgaaata aggcatcaat tgtaacaaat tctcctgcct ctgcagcctt
     1381 caaatgacgg gcaagaaagg ctttctcttc cccaac
//
LOCUS       DAVHSY010000098         1235 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.101, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000098 DAVHSY010000000
VERSION     DAVHSY010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1235
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.101"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(252..497)
                     /locus_tag="VVR43_002055"
     CDS             complement(252..497)
                     /locus_tag="VVR43_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150347.1"
                     /translation="MDIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSTSPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            complement(478..840)
                     /locus_tag="VVR43_002056"
     CDS             complement(478..840)
                     /locus_tag="VVR43_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU6150348.1"
                     /translation="MELVLPNNYVVLEQEEMIYLDGGGVGCNWWNKRDNIAAAAVSGG
                     MSVYQTYAIKKLIANRGMMSRVVRSAITRYIGGVSMATITNALNIAATVAEVFSLGGA
                     IAYGLDIVDGKFDGYLWA"
BASE COUNT          451 a          244 c          144 g          396 t
ORIGIN      
        1 acaaaaatcc ccttggaatc aatcaatgga aaataaaata ttgcaactag aagcgaataa
       61 aatcccgcta ataaatattt ctgatcatct ttcattcaaa acaccatatt atttactaag
      121 aatacatcaa tacaatagag caactctgta agtcaatatt tgataaagca aagctttaaa
      181 cccttcccca gacgttagct tttattcaac ccactacagt tgacaaggag cccaaattat
      241 tgataaaaac tttagtcatc atcgtctcta taaaaatatt ttctatacac tcttgataat
      301 accaaaatta atgccaatat cataccaaga gctataataa tagaatttat tagatttatt
      361 ttagtatatc caatcactag tccaataatt ggactggtag acatgcttag atataataaa
      421 aataacaaaa aatgaatttc accaattcct gcaaaaaaat gtttcatagc tatagtttta
      481 cgcccataaa tatccatcaa atttaccgtc tacgatatct aaaccatatg caatggctcc
      541 tcctaatgag aagacttcag caacagtagc cgcaatatta agagcattag taatagttgc
      601 catactaact ccaccaatat atcttgttat agcacttcta acgactcggc tcatcatacc
      661 acgattagca attaactttt taatggcata tgtctggtat actgacatcc ctccagaaac
      721 tgcagctgca gcaatattat cacgtttgtt ccaccagtta caaccaacac cacccccatc
      781 aagatatatc atctcttctt gctcaagaac aacataatta tttggtaata cgagttccat
      841 ttattttctc cttttttatt aagcatagtt aggatagttt cctaacaagt gatcgttgac
      901 tttgtttata gcacttagtt acctagataa gatatccttt agcttgcttc caaaatttaa
      961 gtctgcacct ataatatgag ttcatattag tactgctaaa tcctatctat agtaatgtca
     1021 aacacctaaa taaagtcatc tctccgattc attcaagaaa tgaagaaagg caaaaaatct
     1081 ttaaaataag aaaaatgcat attatcaggt gttcaaaaat attgatgata tacgttatat
     1141 agatagaaag atttactcaa tctcattttc aaattgagtt ttttcccaac ctcgttttta
     1201 atttatatct tcaatagaat ctaatgaccg agcta
//
LOCUS       DAVHSY010000099         1197 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.102, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000099 DAVHSY010000000
VERSION     DAVHSY010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1197
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.102"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            33..484
                     /locus_tag="VVR43_002057"
                     /pseudo
     CDS             33..484
                     /locus_tag="VVR43_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            649..948
                     /locus_tag="VVR43_002058"
     CDS             649..948
                     /locus_tag="VVR43_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU6150349.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1057..>1197)
                     /locus_tag="VVR43_002059"
     CDS             complement(1057..>1197)
                     /locus_tag="VVR43_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU6150350.1"
                     /translation="GYEKSFQSLKQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKS
                     FG"
BASE COUNT          415 a          233 c          206 g          343 t
ORIGIN      
        1 taataacgat actagataat gaggaaaatg caatggcaaa cccaactttc ggagaaaaaa
       61 agtgaataca gactatattg ctcgctatgg cgtatatgca gttatcccta atcctgaaca
      121 aaaacaaatt gttcttgttc aagaaccaaa tggtgcttgg ttcctaccat gtggaaaaat
      181 tgaagcaggt gaaaatcatc aggaagccct aaagcgtgag ttgattgaag agcttggttt
      241 cacagcagaa attggtacct attacggaca agctgacgaa tatttctatt ctcgtcatcg
      301 tgatacctac tactacaatc ctgcctacct ctatgaagca actcctttca aagaagtaca
      361 aaagccacta gaaaacttta atcatattgc ctggttccct attgacgagg ctatcaaaaa
      421 ccttaaacgt ggtagccata aatgggccat tgaatcttgg aaaaaacagc ataagattgg
      481 ctaatactct tcgaaaataa aattcaaatc acgtaagcgt cgccttaccg tactcaagta
      541 tagcctgcgg ctagcttcct agtttgctct tttattttca ttgagtataa atcaagcgac
      601 tttattcaaa aagtgctata atagaattag aaaatcggag gaaatattat gaagcttatc
      661 aatacgacaa actcacactc gcaacttgta aaaagtcagc tagaaagtac cgatgcaacc
      721 cttgttgagg tttattctgc agggaataca gatgttattt ttacccaagc tccgcttcac
      781 tatgaaatcc tcatctcaaa caaacaccgt gctattcgtg agcctgaaat cgaaaccatt
      841 caagaatttt tcttgaaacg taaaattgat aaggcctctg ttgatgaagc caatatcaag
      901 acactctact cagagaaatt aattggaatt tcaatcccaa tcaagtaaga aaattgagta
      961 aaaactcgat ttgagagaaa gtccaataag tctttcaata ataaaacgca tagtagcaag
     1021 agttttgtac tgaccccaaa aagttagaca attaatttat ccgaaggatt tagttctgta
     1081 ttgcacaggg ctaagtcctt ttagttttac cttaattcgt ttattgttgt agtaatcaat
     1141 atagtctaca atggcttgtt ccaattgctt aagcgactga aacgacttct cataacc
//
LOCUS       DAVHSY010000100         1158 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.103, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000100 DAVHSY010000000
VERSION     DAVHSY010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1158
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.103"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            540..908
                     /locus_tag="VVR43_002060"
     CDS             540..908
                     /locus_tag="VVR43_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HEU6150351.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGCNWWNSRGSFATVLDVDL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALTVTGFSLG
                     GAIAYGVDWADGSLDGYIFA"
BASE COUNT          384 a          118 c          243 g          413 t
ORIGIN      
        1 ttttcgtgaa aaaagttaac gtaattttga aatgagctta ataagaggta ctatgtaggt
       61 agaaaataaa gataggagaa aaagtatgaa taaaaaaata ttttgtattc tagtatgtat
      121 tatatcattg attagtctag ctataatctt tccatggggc tggtcgatat aatgtaaggg
      181 agcttgagtt gttagtggag gataaaatgt taagagtaat agtagttatt caatctttag
      241 taataatact gcttgctgtt gctttattat tatctcggaa aaactttgat tcgttaaatg
      301 ttgttcttat aatgatgatc gtatcacaat tgttgttatt agtatatttg ataaaatcag
      361 ggaatcagtg attagctgtt atttgaatta agtaaactgt taagcttcaa gcagtaactg
      421 gttttaaata tttaaaataa gataaaggaa ggaagtctaa tttaggtaac taaacaaagc
      481 ctgcgatcac ttgttaggaa accatcctaa ccatgcttaa taaaaaaagg agaaaataaa
      541 tggaactcgt attaccaaat aattatgttg ctcttgagca agaagagatg atgtaccttg
      601 atgggggtgg tgttggttgt aactggtgga atagtagagg tagttttgca acagttctgg
      661 atgtagattt ggccatctat agtggtggtg caacaattta ttctgcttat gcgataaaaa
      721 aagctatctc agctaataga ggggctatta cgagaacatt acgtagttta ataattaaac
      781 atgtaggtag tgcagctggc catttagtca atactgcact aactgttact ggattttcac
      841 taggtggagc aatcgcatat ggggttgatt gggctgacgg tagcttagat ggttatattt
      901 ttgcttaaaa tgaaacattt tttgcaggaa ttggtgaaat aaactttgta agttatttat
      961 tgtatatatg tgtaggaata gccccttttt ttcacgtata tataataggt tctgaaatga
     1021 attttgtgaa aatagtgtta tctattttgg gaattatatt tgtttgtatt ttaactattg
     1081 ctcgaattta taggactttt ttctataaag aatagtttgg acttgaaatg tatttaaaaa
     1141 caagaggttg gtagatta
//
LOCUS       DAVHSY010000101         1108 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.104, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000101 DAVHSY010000000
VERSION     DAVHSY010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1108
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.104"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(<1..214)
                     /locus_tag="VVR43_002061"
     CDS             complement(<1..214)
                     /locus_tag="VVR43_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEU6150352.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIK"
     gene            complement(227..966)
                     /locus_tag="VVR43_002062"
                     /pseudo
     CDS             complement(227..966)
                     /locus_tag="VVR43_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
BASE COUNT          398 a          203 c          115 g          392 t
ORIGIN      
        1 ttttaatttc agaaaatgta tcaaaaaaag taatatttaa gttattctcg caaaaaaact
       61 tcataagctc ttcattttta gatggaagaa tgcccttttt taaattattt atttttacag
      121 aatctatatc atatgcaaca actttatatt tagatgcaaa tagtaacgcg taggccagcc
      181 caacatgccc caaaccaatt actgctatat tcataaaact acttccttat ttcttaatcc
      241 aaaatataat agaataaact gccccattcc ttaaatacaa ctctttaata ttgtttaaaa
      301 gtttttcaac tgatttccag attatcaaaa tctgagattt atagcacaat attgatgata
      361 ttctatcaat ataatgtttt tcatcgagtt cctcttgata catttttaat tctttagttt
      421 ttcccatata actaaccata ctactatcac ttacatatgg gaaatcctca taatatatta
      481 ctttataacg cataaattca agcgcccttc caatactatt cacaaaaaca tgatcaacat
      541 ggtcaccaag tgaaagcgga caatatacga cacatttgtc gtctaaatgc attaacagct
      601 cttttatgat atcattcttt aatgtgtcct cattttttaa ttcactatag atatgacggt
      661 atagaaaatt gccatttcta tctttcctat agagacattc atagtacgat aagtgtctaa
      721 aatcacattg tagacgttca caagctaacc tatcttcttt cttcctttct tcaatcggat
      781 attacacaac ttatgaaatt gcttagcaga gggctgtagc tgttgactca aagggtaacc
      841 agaaaatata gtaataacaa gtacaatttc tccttctgaa gttaattttg aaatataatc
      901 accacaggaa aaaattgcgt catctaaatg tggagataaa aagatatact tagtattgtt
      961 actcataacc attccctcta caatttatct aaaaactcac taagtgtctg attaaattcc
     1021 acatcatcaa aaaaattcac cttattctta ataatgaata tttcgttaaa taaacatata
     1081 tataaatatt tcaatatcct ttcaatat
//
LOCUS       DAVHSY010000102         1088 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.105, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000102 DAVHSY010000000
VERSION     DAVHSY010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.105"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            15..1076
                     /locus_tag="VVR43_002063"
     CDS             15..1076
                     /locus_tag="VVR43_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU6150353.1"
                     /translation="MFKNFKKIAFTSSLILLAACSNNASNTNQSTDEGSVDKSQEIVI
                     YTNSASNGRADWLQTKASEQGYNLRLVDISGGELADRLIAEKNNAVADMVIGLNKLEF
                     NRIKAEKLLVKYSPKWADEVDSSLGDSEGYYSPIVNQPLVLIGNKDAKMPSDWTDFTD
                     SSYKGKYGISKLSTGTSKNIFASIVSRYKDEKGELGISDEGWKVAKAYLKNAHVYAEG
                     EDYISSIMDNNNDLKYSMMWGSGVLQNQKEREYKFQVMSPKVGVPYVTEQVGILNTSK
                     KQALLKEFVDWFGSSELQKEWSDKFGSIPANKKALEQAKDELKQFANSVKPQELDWEF
                     IGKNIDSWIEKAQLEFVEQ"
BASE COUNT          405 a          145 c          209 g          329 t
ORIGIN      
        1 aaaggagaac tatcatgttc aaaaacttta aaaagattgc attcacttct tcactaattt
       61 tacttgctgc ttgctcaaac aatgcttcaa atacaaatca gtctactgat gaaggaagtg
      121 ttgataaatc tcaagaaatt gtaatctata caaattcggc ttctaatgga cgtgcagatt
      181 ggttacaaac taaagcatca gagcaaggat acaatcttcg tttggtagat atttcaggtg
      241 gagaactagc tgaccgtttg attgcagaaa agaataatgc tgtggctgat atggtaattg
      301 gattaaataa attagaattt aatcgtatta aagctgaaaa acttcttgta aaatactcac
      361 caaaatgggc tgatgaagta gatagctctt tgggagattc tgaagggtat tattcaccaa
      421 ttgtaaatca accattagtt ttgattggta ataaagatgc taaaatgcca tccgactgga
      481 cagattttac tgattcatct tataaaggta aatatggtat ttcaaaatta agtacaggta
      541 catctaagaa catctttgca agtattgttt cgagatataa agatgaaaaa ggtgagttag
      601 gaatatctga tgaaggttgg aaagttgcaa aagcttacct taaaaatgca cacgtttatg
      661 cagaaggtga agactatatc tcttcaatta tggataataa taatgatcta aaatatagta
      721 tgatgtgggg atctggtgtt ctacaaaatc aaaaagaacg tgaatataaa ttccaagtaa
      781 tgtcaccaaa agttggtgtt ccttatgtaa ctgaacaagt tgggatttta aatacaagta
      841 agaagcaagc attattaaaa gaatttgtag attggtttgg ctcttcagaa cttcaaaaag
      901 aatggtctga taaatttggt tcaattccag ctaataaaaa agctctagag caagcaaaag
      961 atgaactcaa acagtttgct aatagtgtta aaccacaaga acttgactgg gagtttatcg
     1021 ggaaaaacat cgattcttgg attgaaaaag cacagcttga atttgttgaa caataatagt
     1081 taggatta
//
LOCUS       DAVHSY010000103         1058 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.106, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000103 DAVHSY010000000
VERSION     DAVHSY010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.106"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..559
                     /locus_tag="VVR43_002064"
     CDS             <1..559
                     /locus_tag="VVR43_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6150354.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(507..1052)
                     /locus_tag="VVR43_002065"
     CDS             complement(507..1052)
                     /locus_tag="VVR43_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6150355.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVATSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          380 a          171 c          154 g          353 t
ORIGIN      
        1 gaacaaagac gaaacaacct cttatcctat atatgaaatc ccagaagcat ggagatatat
       61 taaatttgct agcctagtta acttcagaat aggaaaaact cctccacgca gtgaagctac
      121 tttttgggga actgaaatac cctgggtatc tatatcagat atgcctatat ctggttatgt
      181 aactaatacg agagaatcta tttctaaatt agcattaaaa tcaaagaaaa tagacatttc
      241 acctaaagga actttattaa tgagttttaa attatctatt ggaaaagttg ccatattgga
      301 tattcctgcc actcataatg aagccattat atcgatattc ccctatgcta acaaagaaaa
      361 tattatcaga gattacttaa tgatattttt gccacttatc tctactttag gtgattcaaa
      421 agatgctatc aaagggaaaa cattaaatag taccagtatc tccgaattat taatccctat
      481 ttctaatcat gaagagatga aaagaatcat ttccaaagtt gatttacttt ttcaaaaagt
      541 ttctcaactt tttgagtaat aagttcctgt tcctcaaaag gagctaacgg aattaatagc
      601 tcgcttagtg tagttttagg aatattatat aaagcttgac ctgatagttt agttattgct
      661 ttcaattgtt tataaaataa cggagaggac aagttaaata atagaaattt tgaaataatc
      721 tctgaacttt cgaatggtgt taattggaaa ataaatccac cagccacaac accatcatag
      781 tctttatcga ttcttgcaaa ctttccaata tgttctaaag aggttgctac aggtgttatt
      841 agctgattat gttttaaata aacttgctca gaggagatga attgtgtatc aatgtagtaa
      901 tcattatcca acagagaaaa ttctaaaggc ttaatattac caccacgtat aattctaaca
      961 cctttattat taatgcttaa atcgcccttc ttgtaagaaa gacctgtatt cattgaaaaa
     1021 atatctttta tttttataac aacccaattc ataggtat
//
LOCUS       DAVHSY010000104         1038 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.107, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000104 DAVHSY010000000
VERSION     DAVHSY010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1038
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.107"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            107..>1038
                     /gene="pspC"
                     /locus_tag="VVR43_002066"
     CDS             107..>1038
                     /gene="pspC"
                     /locus_tag="VVR43_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     LPXTG-anchored form"
                     /protein_id="HEU6150356.1"
                     /translation="MFKSNHERRMRYSIRKFSVGVASVAVASLFMGSVVHATEKEGST
                     QAATSFNRGNGSQAEQRGELDLERDKAMKAVSEYVGKMVRDAYVKSDRKRHKNTVALV
                     NQLGNIKNRYLNEIVHSTSKSQLQELMMKSQSEVDEAVSKFEKDSFSSSSSGSSTKPE
                     TPQPENPEHQKPTTPAPDTKPSPQPEGKKPSVPDINQEKEKAKLAVATYMSKILDDIQ
                     KHHLQKEKHRQIVALIKELDELKKQALSEIDNVNTKVEIENTVHKIFADMDAVVTKFK
                     KGLTQDTPKEPGNKKPSAPKPGMQPSPQPEVKPQL"
BASE COUNT          407 a          189 c          203 g          239 t
ORIGIN      
        1 tttacccact acaaatatta tagagccaaa taatgtagca aatttcatat acaattcata
       61 ttagcaggat atactgtagt taattaaaat tatggagaat atagacatgt ttaaatcaaa
      121 tcatgagcga agaatgcgtt attccattcg taaatttagt gtaggagtag ctagcgtagc
      181 tgttgccagt ctttttatgg gaagtgttgt acatgcgaca gagaaagagg gaagtaccca
      241 agcagccact tcttttaata ggggaaatgg aagtcaggca gaacaacgtg gagaactcga
      301 tttagaacga gataaggcaa tgaaagcggt cagtgaatat gtaggaaaaa tggtgagaga
      361 tgcctatgta aaatcagata gaaaacgaca taaaaatact gtagctctag ttaaccagtt
      421 gggaaacatt aagaacaggt atttgaatga aatagttcat tcaacctcaa aaagccaact
      481 acaggaactg atgatgaaga gtcaatcaga agtagatgaa gctgtgtcta aatttgaaaa
      541 ggactcattt tcttcgtcaa gttcaggatc ctccactaaa ccagaaactc cgcagccgga
      601 aaatccagag catcaaaaac caacaactcc agctccggat accaaaccaa gccctcaacc
      661 agaaggcaag aaaccaagcg taccagacat taatcaggaa aaagaaaaag ctaagcttgc
      721 tgtagcaacc tacatgagca agattttaga tgatatacaa aaacatcatc tgcagaaaga
      781 aaaacatcgt cagattgttg ctcttattaa ggagcttgat gagcttaaaa agcaagctct
      841 ttctgaaatt gataatgtaa ataccaaagt agaaattgaa aatacagtcc acaagatatt
      901 tgcagacatg gatgcagttg tgactaaatt caaaaaaggc ttaactcagg acacaccaaa
      961 agaaccaggt aacaaaaaac catctgctcc aaaaccaggt atgcaaccaa gtcctcaacc
     1021 agaggttaaa ccgcagct
//
LOCUS       DAVHSY010000105          985 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.108, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000105 DAVHSY010000000
VERSION     DAVHSY010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..985
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.108"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            205..543
                     /locus_tag="VVR43_002067"
     CDS             205..543
                     /locus_tag="VVR43_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU6150357.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKIKGTRITK"
     gene            640..>985
                     /locus_tag="VVR43_002068"
     CDS             640..>985
                     /locus_tag="VVR43_002068"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150358.1"
                     /translation="MSPGTFIALTGAAVLTKKLINYIKVGGLGGWLIGAAAGVLALIF
                     LIKICVDTTIKVLLNRIFKASKVMKRRIFSLFVLDLMVYIFLGYVLVIQKDVYLFSIL
                     IIFSNFSVPFIRE"
BASE COUNT          322 a          123 c          213 g          327 t
ORIGIN      
        1 tcgatataat gtaagggagc ttgagttgtt aaaggaggct tagtccttgg acaaaaatct
       61 gctgtactac aatgcttgga aagatatcaa gaacaaagaa tgatacgatt gaaactaaac
      121 tgattcaaga actactgggc agtgattgag gtttgggtga catcaaagaa aagttagatt
      181 aattctaaag aattgagtat ttctatgtta aaaaaatatc cttgtacgat gcaacatgat
      241 cagtcagatt gtgctgcggc agttgtttca acagttcttt tatcttacaa aaaggaacta
      301 tcaatcatga agattcggga aattattggt acagacatgt atggaacgac tgtcagtggt
      361 attgtttcag gtctgaataa gttgaatttt acagtaaaag ctgttcgagt agcactggaa
      421 gatttgactc caaaattaac atttcctgcg attcttcaag ttaagaatga tttaggtcaa
      481 aatcattttg tggtattaca tagtataaag gagaaaataa agggaactcg tattaccaaa
      541 taattatgtt gctcttgagc aagaggagat gatgtatctt gatggggggg ggcttattta
      601 agcaagagtg cttgtcaagg aatttgcgca gctttagcta tgagtccagg aacttttata
      661 gcattgactg gagctgcagt tttaacaaaa aaactaataa actatattaa ggttggaggc
      721 cttggaggtt ggcttattgg tgcagcagca ggtgtattgg ctcttatctt tttgataaaa
      781 atttgtgtag atactacgat aaaggttcta ttaaacagaa tctttaaggc aagtaaggta
      841 atgaaaagga ggatattttc tctttttgta ctagatttga tggtctatat atttttaggt
      901 tatgttttag tgatacaaaa agacgtatat ctgttttcaa ttctgataat tttttctaat
      961 ttttcagttc cctttatcag agaaa
//
LOCUS       DAVHSY010000106          967 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.109, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000106 DAVHSY010000000
VERSION     DAVHSY010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..967
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.109"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            150..>967
                     /locus_tag="VVR43_002069"
     CDS             150..>967
                     /locus_tag="VVR43_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6150359.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLS"
BASE COUNT          328 a          192 c          159 g          288 t
ORIGIN      
        1 atacctctta ttaagctcat tttaaaatta cgttaacttt tttcacaaat ttatttcgac
       61 tttctttttt actttttaca ttgctatgat acaatatttt taacaagatt ttattatttg
      121 ttaacttttt tcacagaaag gagaaaatca tgcgttatga tttcggaaag gtctataaag
      181 aaatacgtga gtcaaagggg ctgacccaag aagaggtctg tgggggtgtt ctctcaagaa
      241 ccagcttatc aaaaatcgaa agtggcaaga caaccccaaa atatgaaaat atggaatttc
      301 ttctccgtca aatcaatatg agttttgaag agtttgaata tatctgtcaa ctttatcaac
      361 caagtcaacg cacagagatt atgcaaacct atctcaatat gcgttctatt atcgggacca
      421 gcgatcttgt caatttattt caaaaatgcc aagactacct caagacccac cacgatctcc
      481 ctatagaaga aatcagagat atgcttgaag ttgtcattta tatccgtcaa cacggggcag
      541 gggaactatc agatcacgca gaacaggttg tcaaaaaact ttggagaaaa attgaaaaac
      601 aagatacatg gtatgagagt gatctaaaaa tcctcaatac cattcttttc agttttccca
      661 ttgaatacct ccatctcatc actggaaaaa tattgcaacg cctagaagtc tataaaaact
      721 atcaacattt atatgacttg cgaatagcaa tcctgctcaa cctttccaca ctctatctat
      781 acaatcaaga taaaaacatg tgtaagcaaa tctgctacac tttactggag gacgccaaga
      841 ataagaaaag ctacgatagg ctggctatct gctatgtccg cattgggatt tgtacagacg
      901 attctaaact tatccaaaaa gggttctccc ttctggagct gaccgaggaa acttctatgc
      961 tgtctca
//
LOCUS       DAVHSY010000107          926 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.110, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000107 DAVHSY010000000
VERSION     DAVHSY010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..926
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.110"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(157..303)
                     /locus_tag="VVR43_002070"
     CDS             complement(157..303)
                     /locus_tag="VVR43_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150360.1"
                     /translation="MKTKEQTRKLAAGCSKHCFEVVDRTDEVSNHTHGKATLTWFEEI
                     FKEY"
     gene            461..679
                     /locus_tag="VVR43_002071"
     CDS             461..679
                     /locus_tag="VVR43_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEU6150361.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
BASE COUNT          289 a          141 c          182 g          314 t
ORIGIN      
        1 cgtgtttgga ttattacctt gaacgacatg cgttaaaagt tagttgaacc gccgtatgcc
       61 gaacggcacg tacggtggtg tgagaggggc tagagattat cccctactcg atttcgaaat
      121 ctagtggaat gaatctggaa tagtccatcg agctttctaa tactctttga aaatctcttc
      181 aaaccacgtc aacgtcgcct tgccgtgcgt atggttactg acttcgtcag ttctatccac
      241 aacctcaaaa cagtgttttg agcaacctgc ggctagtttc ctagtttgct ctttggtttt
      301 cattgagtat aacacattgt tagaagttgg tttaaatttc ctaatcagtt tgttcacatt
      361 taccttcgat atattatatc ccatagttaa ggttggtcat acagatgatt atagccatgg
      421 agccgtaaaa cttagtgttt ctttagttga caaagatgcc atgaaaaaaa tatctgtaac
      481 tgtaatagga tattttgaaa taaatataga tgaaaatatc accgatattc tatacgtaaa
      541 tggtactgct attctttatc cttatttacg ttctattgtt tcaatagttt cggcaattga
      601 tagcagtgaa gcaatgttgc tacctaccat taatgtttta gagttactag ataaatctca
      661 accttttgaa gaagaataat ttattagctc actaaattga gggtaaggaa aagtaaaagc
      721 agtaagaaaa atgtcttgca ttatacagca actttttggg aatgagtaga tggattgaat
      781 aaaatttgat taagagtgga tgatttatct gtagattatt attggacagt tagtcttgaa
      841 gtagtctaag aattaggtta taatcagtag aagccttgct aataatgagg aggttagttt
      901 atgtatagta gactgaatct aaaata
//
LOCUS       DAVHSY010000108          892 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.111, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000108 DAVHSY010000000
VERSION     DAVHSY010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..892
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.111"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            1..892
                     /locus_tag="VVR43_002072"
                     /pseudo
     CDS             1..892
                     /locus_tag="VVR43_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          269 a          194 c          153 g          276 t
ORIGIN      
        1 ctttcaaaaa ccttctaaaa ttccttatct tgaaacgact ggtataccta ctagaattct
       61 ccttagaaaa cgctgtttca agtgctatca ctgttcaaaa atgatggttg ctgagactcc
      121 cctggtaaag aaaaatcacc aaatccctcg tatcatcaac caaaagattg ctcaaaagtt
      181 aattgaaaag atttctatga ctgatattgc ccatcagctt tccatctcaa cttcaactgt
      241 cattcgaaag ctcaatgact tccactttga gtgtaatttt agaaatctgc ctaagattat
      301 gtcttgggac gttgaaacag tccggggagt gactgtttca atcgggagat ggagatgagc
      361 tttattgcgc aagattttga taatcttaat attatcactg ttcttgaagg cagaacacaa
      421 gctgtcatcc gaaatcactt tcttcgctac gatagagccg ttcgttgtca agtgaaaatc
      481 attacgatgg atatgtttag tccttactat gacttggcta aacagcttcg ctttcaaatt
      541 tctaggctca ggctgaaaca gtctcccaga ctgtttcact cccgaatgct aaaatcgttc
      601 ttgatcgctt tcacattgta caacatctta gccgtgctat gagtcgtgtg cgtgtccaaa
      661 tcatgaatca gtttcatcga aaatcccatg aatacaaggc tatcaagcgc tactggaaac
      721 tcattcaaca ggatagccgt aaactgagtg ataaacgttt ttatcgtcct acttttcgta
      781 tgcacttaac caataaagag attttaaaca agcttttgag ttattcggaa gacttgaaac
      841 accactatca actctatcag ctcttgcttt ttcacttcca gaataaggaa cc
//
LOCUS       DAVHSY010000109          881 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.112, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000109 DAVHSY010000000
VERSION     DAVHSY010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.112"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(8..81)
                     /locus_tag="VVR43_002073"
     tRNA            complement(8..81)
                     /locus_tag="VVR43_002073"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45..47),aa:Ile,seq:cat)
     gene            complement(95..168)
                     /locus_tag="VVR43_002074"
     tRNA            complement(95..168)
                     /locus_tag="VVR43_002074"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(132..134),aa:Met,seq:cat)
     gene            complement(174..247)
                     /locus_tag="VVR43_002075"
     tRNA            complement(174..247)
                     /locus_tag="VVR43_002075"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(211..213),aa:Pro,seq:tgg)
     gene            complement(263..336)
                     /locus_tag="VVR43_002076"
     tRNA            complement(263..336)
                     /locus_tag="VVR43_002076"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(300..302),aa:Arg,seq:acg)
     gene            complement(346..431)
                     /locus_tag="VVR43_002077"
     tRNA            complement(346..431)
                     /locus_tag="VVR43_002077"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(395..397),aa:Leu,seq:taa)
     gene            complement(439..510)
                     /locus_tag="VVR43_002078"
     tRNA            complement(439..510)
                     /locus_tag="VVR43_002078"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(476..478),aa:Gly,seq:gcc)
     gene            complement(533..605)
                     /locus_tag="VVR43_002079"
     tRNA            complement(533..605)
                     /locus_tag="VVR43_002079"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(570..572),aa:Thr,seq:tgt)
     gene            complement(624..705)
                     /locus_tag="VVR43_002080"
     tRNA            complement(624..705)
                     /locus_tag="VVR43_002080"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(669..671),aa:Leu,seq:tag)
     gene            complement(711..783)
                     /locus_tag="VVR43_002081"
     tRNA            complement(711..783)
                     /locus_tag="VVR43_002081"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(748..750),aa:Lys,seq:ttt)
     gene            complement(808..880)
                     /locus_tag="VVR43_002082"
     tRNA            complement(808..880)
                     /locus_tag="VVR43_002082"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(845..847),aa:Asp,seq:gtc)
BASE COUNT          232 a          257 c          199 g          193 t
ORIGIN      
        1 attcaaatgg accttgtagg acttgaacct acgaccactc ggttatgagc cgagagctct
       61 aaccagctga gctaaaggtc cgacaagatc attatagcgg cgaaggggat cgaacccccg
      121 acctcccggg tatgaaccgg acgctctagc cagctgagct acaccgccat gaatcgggaa
      181 gacaggattc gaacctgcga caccttggtc ccaaaccaag tactctacca agctgagcta
      241 cttcccgagt taaatagaaa aatgcaccct agaggagtcg aacctctaac cgcctgattc
      301 gtagtcaggt actctatcca gttgagctaa gggtgctcca tattatgccg aggaccggaa
      361 tcgaaccggt acgatcgtta ccaatcgcag gattttaagt cctgtgcgtc tgccagttcc
      421 gccaccccgg cctctctaag cgaacgacgg gattcgaacc cgcgaccccc accttggcaa
      481 ggtggtgttc taccactgaa ctacgttcgc actgttttct tctatctaaa aatgccggct
      541 acatgacttg aacacgcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      601 ccggctcatt tgttatatct taatgcgggt taagggactt gaacccccac gccgttaagc
      661 gccagatcct aaatctggtg cgtctgccaa ttccgccaaa cccgcatata tgacccgtac
      721 tgggctcgaa ccagtgaccc attgattaaa agtcaattgc tctaccaact gagctaacga
      781 gtctaaaata acttgcgtta ccttaaacgg tcccgacggg aatcgaaccc gcgatcttcg
      841 ccgtgacagg gcgacgtgat aaccgctaca ctacgggacc t
//
LOCUS       DAVHSY010000110          865 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.113, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000110 DAVHSY010000000
VERSION     DAVHSY010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..865
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.113"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(<1..470)
                     /locus_tag="VVR43_002083"
     CDS             complement(<1..470)
                     /locus_tag="VVR43_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU6150362.1"
                     /translation="MNLSYELSIWEILLRCFLAILFGGIVGYERGVKNQAAGIRTYLL
                     VCLGTCVVMMTNQFITSRYGSGDPSRMGAQVISGLGFLGAGTIMVTNQKVKGLTTAAG
                     LWSSATIGLAIGIGFYEGAILAGVVLIAVLTLFTPLKDYLNSKTKIADYYLVFSS"
     gene            complement(472..>865)
                     /locus_tag="VVR43_002084"
     CDS             complement(472..>865)
                     /locus_tag="VVR43_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEU6150363.1"
                     /translation="IAYTIQKLPFSYRMIRAVFFSIDNDMEEAARSMGASSFYTMVRV
                     IIPYILPVVLSVVVLNFNSLLSDYDLSVFLYHPLFQPLGIVIKQSTDETATLNAQAMM
                     FVYSVILMIMSSAALYLSSLFQGKRGKR"
BASE COUNT          311 a          172 c          134 g          248 t
ORIGIN      
        1 gaactaaaaa ccaagtagta atcagcaatt ttagttttcg agtttaaata atctttaaga
       61 ggagtaaata gagttaaaac tgctatgagt acaactccgg ctaaaatagc accttcataa
      121 aaaccaatgc ctatagctaa accaatagtt gctgaagacc ataatccagc tgctgttgtt
      181 aaacctttaa ctttttgatt agttaccatg attgttcctg cccctaggaa acccaagcca
      241 ctaattactt gggctcccat tcgactagga tcaccgctac cataacgact agtgatgaac
      301 tgatttgtca tcattacaac acaagttccc aaacaaacta gtaagtaggt tctaatccct
      361 gctgcttggt ttttgactcc tcgctcatag ccaacaatgc caccgaaaag aatcgctaaa
      421 aagcacctaa gaagtatttc ccaaatactc agttcgtatg aaagattcat attatctctt
      481 acctcgttta ccttggaata ggcttgataa ataaagagct gcactagaca taatcattaa
      541 aattacagaa taaacaaaca tcattgcctg tgcatttaaa gttgctgttt catcagtaga
      601 ctgtttaata acgattccca atggttggaa aagtggatgg tacaagaata cagataagtc
      661 atagtcagat aataaagaat taaagtttaa cacaactact gataatacga ctggtaaaat
      721 atacggtata ataactcgca ccatagtgta gaaactagat gcacccatac tacgtgcagc
      781 ttcttccata tcattatcta tactgaaaaa tacagcccga atcattctat aagaaaatgg
      841 taatttttga atagtatatg caata
//
LOCUS       DAVHSY010000111          835 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.114, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000111 DAVHSY010000000
VERSION     DAVHSY010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..835
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.114"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            105..584
                     /locus_tag="VVR43_002085"
     CDS             105..584
                     /locus_tag="VVR43_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU6150364.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            678..749
                     /locus_tag="VVR43_002086"
     tRNA            678..749
                     /locus_tag="VVR43_002086"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:711..713,aa:Glu,seq:ttc)
BASE COUNT          311 a          112 c          195 g          217 t
ORIGIN      
        1 gcctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtttataagt gtagaaatga atattacctt catttatggg
      181 aattgtcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg tagatacgat aaagaaccct
      361 atgaagaagt gggagagatc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgcgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ctagtaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gtagttgaca aagtttgaaa agactgtata atagtaagag
      661 ttgaaaataa caactcaggt ccgttggtca aggggttaag acaccgcctt ttcacggcgg
      721 taacacgggt tcgaatcccg tacggactat ggtatgttgc ggttggaaca cttgatgaaa
      781 aaaagtttaa aaaaagctta aaaatcttca aaaaagtgtt gacaagtgaa agtgg
//
LOCUS       DAVHSY010000112          767 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.115, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000112 DAVHSY010000000
VERSION     DAVHSY010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..767
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.115"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            1..767
                     /locus_tag="VVR43_002087"
                     /pseudo
     CDS             1..767
                     /locus_tag="VVR43_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          233 a          161 c          139 g          234 t
ORIGIN      
        1 taaagaaaaa tcaccaaatc cctcgtatca tcaaccaaaa aattgctcaa aagttaattg
       61 aaaaaatttc tatgactgat attgcccatc agctggccat ttcaacttca actgtcattc
      121 gcaagctcaa tgacttccac tttgagtgta attttagaaa tctgcctgag attatgtctt
      181 gggaggttga aacagtccgg ggagtgactg tttcaatcgg gagatggaga tgagcttcat
      241 tgcgcaagat tttgataatc ttaatattat cactgttctt gaaggcagaa cacaagctgt
      301 catccgaaat cactttcttc gctacgatag agccgttcgt tgtcaagtga aaatcattac
      361 gatggatatg tttagtcctt actatgactt ggctaaacaa cttcgctttc aaatttctag
      421 gctcaggctg aaacagtctc ccagactgtt tcactcccga atgcaaaaat tgttcttgat
      481 cgctttcaca ttgtacaaca tcttagccgt gctatgagtc gtgtgcgtgt tcaaatcatg
      541 aatcagtttc atcgaaagtc tcatgaatac aaggctatca agcgctactg gaagctcata
      601 caacaggata gccgtaaact gagtgataag cgattttatc gtcctacttt tcgtatgcac
      661 ttaaccaata aagagatttt aaacaagctt ttgagttatt cggaagactt gaaacaccac
      721 tatcagctct atcaactctt gctgtttcac tttcagaata aggaacc
//
LOCUS       DAVHSY010000113          545 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.118, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000113 DAVHSY010000000
VERSION     DAVHSY010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..545
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.118"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            371..532
                     /locus_tag="VVR43_002088"
     CDS             371..532
                     /locus_tag="VVR43_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150365.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
BASE COUNT          213 a           77 c          108 g          147 t
ORIGIN      
        1 aaattttaaa aagattaata actctcgata aattttgaac cttaacaatt gaatagacca
       61 agacaaggcg ttaattattt ttggagcgta ataacctatc cgtcaagatc tttcggctga
      121 ataattcggc aaaaaaagtt ctgctaagca aaaagaaagt gagcgataag taagagtttg
      181 aatataggga gggataccct atccgctatg aagaaaatga ggataatgat acttctaagg
      241 ttgaagccgg ctcatccgga atagaggcgg aggtgagatt cctatgttgc taatccaaag
      301 cacttgtcaa tgtcaaaaaa cttaattaaa caaataatta ttagatataa aactttagag
      361 gaggtatata ttggacaatg actggaatgg attggctgat ttaatagcaa atctgattgc
      421 aaaatatgct ggtgctttag atttagataa tctacccgat ccaacgccag caaaaaatca
      481 agagatgaaa aatagttttg acatggcaaa aacacaaatt gagacggact aataaaagtg
      541 ttata
//
LOCUS       DAVHSY010000114          494 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.120, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000114 DAVHSY010000000
VERSION     DAVHSY010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.120"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..198
                     /locus_tag="VVR43_002089"
     CDS             <1..198
                     /locus_tag="VVR43_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150366.1"
                     /translation="INHIKYSVDFVNKELGIDLSIEIDKLIKQGEKPSVIAQIKKFQD
                     QVNKDNEYREMMKNKKMDQER"
     gene            272..445
                     /locus_tag="VVR43_002090"
     CDS             272..445
                     /locus_tag="VVR43_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150367.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
BASE COUNT          244 a           75 c           70 g          105 t
ORIGIN      
        1 attaatcata taaaatattc agtagatttt gtaaacaaag aacttggtat agatttatcc
       61 atagaaatag ataagctaat aaaacaggga gaaaaaccaa gtgtaatagc acagattaaa
      121 aagttccaag accaagtcaa taaagataat gaatacagag aaatgatgaa aaacaagaaa
      181 atggatcaag aaagataaga cctggtaaaa atatcttatc caagctataa tatgaccaaa
      241 caactaaagt cagatctagg aggtaataga gatgaataaa aggcaagagc taatagatga
      301 actcataaaa gcaaatgaag atggaacata caaaacctat aaaagcacag aagaaataaa
      361 agcaatgaac aatgaagaaa tacagattat atattccaac atgaaaaact atctatcaga
      421 caaaagaaca cacataaact attaacccca attattcacc cctaatctaa aaaccatcca
      481 gaatccttgc ctta
//
LOCUS       DAVHSY010000115          469 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.122, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000115 DAVHSY010000000
VERSION     DAVHSY010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.122"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..>469
                     /locus_tag="VVR43_002091"
     CDS             <1..>469
                     /locus_tag="VVR43_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU6150368.1"
                     /translation="HQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDILAFLAP
                     IRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTH
                     SHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAA"
BASE COUNT          151 a           94 c          109 g          115 t
ORIGIN      
        1 ttcaccaaga tttacttgat aataaaggtc gacaagttga ttttgaggct ttggataacc
       61 tgttggaacg actcaaggat gtctcaagtg ataaagtcaa gttagtggat gatattcttg
      121 ccttcttagc tccgattcgt catccagaac gtttaggaaa accaaatgcg caaattacct
      181 acactgatga tgagattcaa gtagccaagt tggcaggcaa gtacacaaca gaagacggtt
      241 atatctttga tcctcgtgat ataaccagtg atgaggggga tgcctatgta actccacata
      301 tgacccatag ccactggatt aaaaaagata gtttgtctga agctgagaga gcggcagccc
      361 aggcttatgc taaagagaaa ggtttgaccc ctccttcgac agaccatcag gattcaggaa
      421 atactgaggc aaaaggagca gaagctatct acaaccgcgt gaaagcagc
//
LOCUS       DAVHSY010000116          462 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.123, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000116 DAVHSY010000000
VERSION     DAVHSY010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.123"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(<1..>462)
                     /locus_tag="VVR43_002092"
     CDS             complement(<1..>462)
                     /locus_tag="VVR43_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6150369.1"
                     /translation="CRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLER"
BASE COUNT          150 a           92 c          106 g          114 t
ORIGIN      
        1 aaccgttcta aaacaggtgt gataaagctg tctgcctctt cagaacaata acgattacca
       61 ggacgaagct gggcattgaa acaataacct gtcttcccct cgaaagcata aagaggatga
      121 tagccatgag cacgatagtg ggcgttataa gcaacacctt cttgcttgcc ataagttgtg
      181 aaatgggtag aatcgatatc tacaatgagt tggtttagct ggtgaaactg taaaaagaat
      241 tcgaccaatt caaggttgag gcatcgcaaa ctatggactg tttcctcgtc agttctggaa
      301 agaaaacggg ataaggttgg ctgtgaagca agctgccctc cttccaacaa ttttggaaag
      361 taggcatcag ctgacaattc tttacaagca tagtccgttc cataacctgt taacagttga
      421 aagaggaact ggacaaggat atctgaatcc gaataacgac ag
//
LOCUS       DAVHSY010000117          421 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.124, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000117 DAVHSY010000000
VERSION     DAVHSY010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.124"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            324..421
                     /locus_tag="VVR43_002093"
                     /pseudo
     CDS             324..421
                     /locus_tag="VVR43_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          157 a          114 c           81 g           69 t
ORIGIN      
        1 ctgaagatga tactgctgct cttcaaaata aattagctac taaaaaagct gaattggaaa
       61 aaactcaaaa agaattagat gcagctctta atgagttagg ccctgatgga gatgaagaag
      121 aaactccagc gccggctcct caaccagagc aaccagctcc tgcaccaaaa ccagagcaac
      181 cagctccagc tccaaaacca gagcaaccag ctccagctcc aaaaccagag caaccagctc
      241 cagctccaaa accagagcaa ccagctaagc cggagaaacc agctgaagag cctactcaac
      301 cagaaaaacc agccactcca aaaacaggct ggaaacaaga aaacggtatg tggtatttct
      361 acaatactga tggttcaatg gcaacaggtt ggctccaaaa caacggttca tggtactacc
      421 t
//
LOCUS       DAVHSY010000118          415 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.125, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000118 DAVHSY010000000
VERSION     DAVHSY010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.125"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..>415
                     /locus_tag="VVR43_002094"
     CDS             <1..>415
                     /locus_tag="VVR43_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type I restriction endonuclease subunit S"
                     /protein_id="HEU6150370.1"
                     /translation="KSIYWNFGQNKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQA
                     PSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLIASTAFIVLDTLLNETYLKYYLL
                     SDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLS"
BASE COUNT          153 a           64 c           54 g          144 t
ORIGIN      
        1 taaaatcaat ttattggaat tttgggcaaa ataagccaga gaaatccttt aggtatatag
       61 atacgtctag tattgataga aaaaagaaca taatcaacta caaaaatcta caatatcttt
      121 cacctgaaca agcgccttcc cgtgctagaa aattagtttc gcagaatagt gtcttatttt
      181 caacagttag accatatcta aaaaatattg ctgtagttag agaacttaaa gagtatttga
      241 tagctagtac agcatttatt gttttggata ctttacttaa cgaaacatat ttgaaatatt
      301 atttattatc agataatttt atcaatcgtg ttaataataa atctactgga acaagttatc
      361 ctgcaatcaa tgattataat tttaatctat tattaattgc tctcccccca ctatc
//
LOCUS       DAVHSY010000119          325 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.130, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000119 DAVHSY010000000
VERSION     DAVHSY010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.130"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            complement(<1..>325)
                     /locus_tag="VVR43_002095"
     CDS             complement(<1..>325)
                     /locus_tag="VVR43_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6150371.1"
                     /translation="KTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSETL
                     YQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIKE
                     MKEGFF"
BASE COUNT           83 a           69 c           79 g           94 t
ORIGIN      
        1 caaaaaatcc ctccttcatc tccttgatga aattctcggc ttgaccacgt ccacgataaa
       61 gctgaaactg gtcttggctt gttccactcg tcatatttgt aacgagagaa ataacatcgt
      121 agaacaagtt tccttctttt cgttcagaga actggcagac acgacgcttg tgcgaccaag
      181 atcctgcttg atagagagtt tctgagtagg cggagtgggg caagatggtt aagtcctcat
      241 cctgtgggca agggagggaa aggtctccaa gacggctcag aacagtattt ttcttgagtt
      301 ttatgaggta gtattgccct gtttt
//
LOCUS       DAVHSY010000120          317 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.131, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000120 DAVHSY010000000
VERSION     DAVHSY010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.131"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..>317
                     /locus_tag="VVR43_002096"
     CDS             <1..>317
                     /locus_tag="VVR43_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HEU6150372.1"
                     /translation="KAEAIRLEEIKTDREEAKRKADAKLKEAVENNAATSEQGEPKRR
                     VKRGVLGEPATPDKKENDAKSSDSSVGEETLPSPSLKPEKKVAEAEKKVAEAEKKAKD
                     QKE"
BASE COUNT          135 a           51 c           83 g           48 t
ORIGIN      
        1 aaaaagcaga ggctataagg ttagaagaaa tcaagacaga tcgtgaagaa gctaaacgaa
       61 aagcagatgc taagttgaag gaagctgttg aaaacaatgc agcgacttca gagcaaggtg
      121 aaccaaagag gcgggtaaaa cgaggagttc ttggagagcc agcaacacct gataaaaaag
      181 aaaatgatgc gaagtcttca gattctagcg taggtgaaga aactcttcca agcccatccc
      241 tgaaaccaga aaaaaaggtt gcagaagctg agaagaaggt tgcagaagct gagaaaaaag
      301 ccaaggatca aaaagaa
//
LOCUS       DAVHSY010000121          316 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.132, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000121 DAVHSY010000000
VERSION     DAVHSY010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.132"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            <1..>316
                     /locus_tag="VVR43_002097"
     CDS             <1..>316
                     /locus_tag="VVR43_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6150373.1"
                     /translation="QVASLLEEREIVTPTYREALITREKSFPTGLDMEFLGKDLPNVA
                     IPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDKEVEVSLLFFIINNSSSSQTNILAQL
                     MD"
BASE COUNT          101 a           57 c           63 g           95 t
ORIGIN      
        1 atcaggtagc aagcttgttg gaagaacgag aaattgtcac tccaacttat cgtgaagcct
       61 tgatcacgcg tgaaaagtca tttccaactg gtttagatat ggaatttcta ggaaaggact
      121 tgccaaatgt agcgattcct cacacagata ttgttcataa tctagctgag aaagtggtgg
      181 ttgttcgatt agaaaaacca gtaacttttc acaatatgat agctcctgat aaggaagtag
      241 aagtatctct actcttcttt atcattaaca attcaagttc aagtcaaacg aacattctgg
      301 ctcagttgat ggactt
//
LOCUS       DAVHSY010000122          275 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.136, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000122 DAVHSY010000000
VERSION     DAVHSY010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.136"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
BASE COUNT           90 a           55 c           41 g           89 t
ORIGIN      
        1 tctaaaaacc atccagaatc cttgccttag cttagatcct ggatggtttc ttttttcacc
       61 caatgggtgt tttttactag acaaaaaaga gtttcccctt tatggtataa gtgtagaaaa
      121 aaacacaaaa agaaaggaaa ctcacatgaa cagtttacca aatcatcact tccaaaacaa
      181 gtctttttac caactatctt tcgatggagg tcatttaacc cagtatggtg gtcttatctt
      241 ttttcaggaa cttttttccc agttgaaact aaaag
//
LOCUS       DAVHSY010000123          267 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.denovo.138, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000123 DAVHSY010000000
VERSION     DAVHSY010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.denovo.138"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
BASE COUNT          105 a           42 c           40 g           80 t
ORIGIN      
        1 gattatacca cattgtgtac tatttttggt tcattttact atattttaga agttatagtg
       61 tagcattcca acttcaaagc actataaagt aaattgaaac aagaacaata caaacaattc
      121 tcgtaaacgg attgcaacca caaaaaagcg gctctataat atttgtagtg ggtaaatcca
      181 ctatagatat tatggagcct attttgtgta gaaaaaaagt cccatatgac ctataatgaa
      241 aagcgacaaa accatcatta gaaagat
//
LOCUS       DAVHSY010000124        23666 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.guided.026, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000124 DAVHSY010000000
VERSION     DAVHSY010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23666
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.guided.026"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            638..952
                     /locus_tag="VVR43_002098"
     CDS             638..952
                     /locus_tag="VVR43_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6150374.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            968..1354
                     /locus_tag="VVR43_002099"
     CDS             968..1354
                     /locus_tag="VVR43_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6150375.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            1383..2768
                     /locus_tag="VVR43_002100"
     CDS             1383..2768
                     /locus_tag="VVR43_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU6150376.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVQAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            2771..2923
                     /locus_tag="VVR43_002101"
     CDS             2771..2923
                     /locus_tag="VVR43_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6150377.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            2946..4208
                     /locus_tag="VVR43_002102"
     CDS             2946..4208
                     /locus_tag="VVR43_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEU6150378.1"
                     /translation="MEGFLLNEQTWLQQLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLFEALERFNPDAPLEMLFDYVRIRFPTTDVQHVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDALVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKKGYLSTIPVDRYPKKRYNGR"
     gene            4153..4365
                     /locus_tag="VVR43_002103"
     CDS             4153..4365
                     /locus_tag="VVR43_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HEU6150379.1"
                     /translation="MCQPYQLTDIQKKDIMGDKTVRVRADLHHIIKIETAKNGGNVKE
                     VMEIRLRSKLKSVLIVHYLKILYNRN"
     gene            4414..4497
                     /locus_tag="VVR43_002104"
     CDS             4414..4497
                     /locus_tag="VVR43_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEU6150380.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            4622..5359
                     /gene="erm(B)"
                     /locus_tag="VVR43_002105"
     CDS             4622..5359
                     /gene="erm(B)"
                     /locus_tag="VVR43_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEU6150381.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            complement(5616..6863)
                     /locus_tag="VVR43_002106"
     CDS             complement(5616..6863)
                     /locus_tag="VVR43_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU6150382.1"
                     /translation="MSHNDSILNILGIKDKNIKIISVEEAEHNNDSVKEYITLITATL
                     SYPINRCRNCGFPTVNKDGFRKTHVRLASLNGRRYELELRKQRYKCKSCHTTFGAITN
                     LTKENQTLSSDLKNQIMLLARKGLSGQLIAEMCHCSPSSVRRTILERMEPHYRVAKLP
                     KHLCFDEFRSIKSVMSFICCDAETHQIVTKLQDRLSPTIVDYFESRYSKAERECVQSV
                     VIDLNAQYQSFIYRLFPNANIIIDRFHLVQLAGRALDNCRISILKQLDKQSQEYKIMK
                     SHWKLFHKKAEDLHPEEVVFLRGVKQYMTRQNAVDLITSKFSKFAEVYQTYQDITKAL
                     NERNSELLESTILDYQKTNTEMDTAIQTLRQNRKYVLNSAKFEYSNGPLEGINRKIKT
                     LKRTCYGFANQKFFFLRIDCIFS"
     gene            7043..7264
                     /locus_tag="VVR43_002107"
     CDS             7043..7264
                     /locus_tag="VVR43_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150383.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            7381..7878
                     /locus_tag="VVR43_002108"
     CDS             7381..7878
                     /locus_tag="VVR43_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEU6150384.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            7853..8359
                     /locus_tag="VVR43_002109"
     CDS             7853..8359
                     /locus_tag="VVR43_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6150385.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            8343..10790
                     /locus_tag="VVR43_002110"
     CDS             8343..10790
                     /locus_tag="VVR43_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6150386.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            10793..12970
                     /locus_tag="VVR43_002111"
     CDS             10793..12970
                     /locus_tag="VVR43_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU6150387.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKAERASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            12967..13968
                     /locus_tag="VVR43_002112"
     CDS             12967..13968
                     /locus_tag="VVR43_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEU6150388.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            13965..14897
                     /locus_tag="VVR43_002113"
     CDS             13965..14897
                     /locus_tag="VVR43_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6150389.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            15142..15258
                     /locus_tag="VVR43_002114"
     CDS             15142..15258
                     /locus_tag="VVR43_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEU6150390.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            15274..17193
                     /gene="tet(M)"
                     /locus_tag="VVR43_002115"
     CDS             15274..17193
                     /gene="tet(M)"
                     /locus_tag="VVR43_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEU6150391.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            17557..17802
                     /locus_tag="VVR43_002116"
     CDS             17557..17802
                     /locus_tag="VVR43_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150392.1"
                     /translation="MRQIGVSYSGFVDESYTLLSLFDDVEQIEKDNRLQTAIDVVREQ
                     FGFLAIQKGTVLTEGSRNIERSKLIGGHSAGGLEGLK"
     gene            17799..18134
                     /locus_tag="VVR43_002117"
     CDS             17799..18134
                     /locus_tag="VVR43_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imsC-like protein"
                     /protein_id="HEU6150393.1"
                     /translation="MKQEKNTVQFSEIRSKGCNDIEMLERFLHGIVETATSKLRQRKL
                     KTTEISIRLVHAKSENRLPLEFTFSIKPTSSSVIIYTEVINRFKECYTGGGIQGFTIQ
                     FDKNTLASA"
     gene            18147..18515
                     /locus_tag="VVR43_002118"
     CDS             18147..18515
                     /locus_tag="VVR43_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150394.1"
                     /translation="MIDRSYLPFQSAREYQDTKMQKWMGFFLSEHASALSDDTNKVTY
                     MSDLSLEKKLLLLSQVYAGQLRTRIQVIEKNKRVSYTGTIPSLTKDFILIKTTTGHIN
                     LKLKDIISIELVEEVLYESA"
     gene            18502..18801
                     /locus_tag="VVR43_002119"
     CDS             18502..18801
                     /locus_tag="VVR43_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150395.1"
                     /translation="MNQLEFQRNHLQMDYYSESYQDFERDFYRYSNMNIPLTFLTDDI
                     LKTMATSRKNYFVLNKEKSRDNRDHFFIFEVSTVDENPLIYHYTYKKTTIYLAEK"
     gene            complement(18919..20382)
                     /gene="msr(D)"
                     /locus_tag="VVR43_002120"
     CDS             complement(18919..20382)
                     /gene="msr(D)"
                     /locus_tag="VVR43_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(D)"
                     /protein_id="HEU6150396.1"
                     /translation="MELILKAKDIRVEFKGRDVLDINELEVYDYDRIGLVGANGAGKS
                     TLLRVLLGELTPPGCKMNRLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLNIQTMSG
                     GEETRLKIAQALSAQVHGILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLD
                     EIVDKIWELKDGKITEYWGNYSDYLRQKEEERKSQAAEYEQFIAERARLERAAEEKRK
                     QARKIEQKAKGSSKKKSTEDGGRLAHQKSIGSKEKKMYNAAKTLEHRIAALGKVEAPE
                     GIRRIRFRQSKALELHNPYPIVGAEINKVFGDKALFENASFQIPLGAKVALTGGNGIG
                     KTTLIQMILNHEEGISISPKAKIGYFAQNGYKYNSNQNVMEFMQKDCDYNISEIRSVL
                     ASMGFKQNDIGKSLSVLSGGEIIKLLLAKMLMGRYNILIMDEPSNFLDIPSLEALEIL
                     MKEYTGTIVFITHDKRLLENVADVVYEIRDKKINLKH"
     gene            complement(20502..21719)
                     /gene="mef(A)"
                     /locus_tag="VVR43_002121"
     CDS             complement(20502..21719)
                     /gene="mef(A)"
                     /locus_tag="VVR43_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012102963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(A)"
                     /protein_id="HEU6150397.1"
                     /translation="MEKYNNWKRKFYAIWAGQAVSLITSAILQMAIIFYLTEKTGSAM
                     VLSMASLVGFLPYAILGPAIGVLVDRHDRKKIMIGADLIIAAAGAVLAIVAFCMELPV
                     WMIMIVLFIRSIGTAFHTPALNAVTPLLVPEEQLTKCAGYSQSLQSISYIVSPAVAAL
                     LYSVWDLNAIIAIDVLGAVIASITVAIVRIPKLGNQVQSLEPNFIREMKEGVVVLRQN
                     KGLFALLLLGTLYTFVYMPINALFPLISMEHFNGTPVHISITEISFAFGMLAGGLLLG
                     RLGGFEKHVLLITSSFFIMGTSLAVSGILPPNGFVIFVVCCAIMGLSVPFYSGVQTAL
                     FQEKIKPEYLGRVFSLIGSIMSLAMPIGLILSGFFADKIGVNHWFLLSGILIIGIAIV
                     CQMITEVRKLDLK"
     gene            complement(22105..22275)
                     /locus_tag="VVR43_002122"
     CDS             complement(22105..22275)
                     /locus_tag="VVR43_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HEU6150398.1"
                     /translation="MKYFEVELENPDEFLKLQTEDFVKANRLLLRKIIQSVTVYEENF
                     VISFKSGIELEV"
     gene            22797..22988
                     /locus_tag="VVR43_002123"
     CDS             22797..22988
                     /locus_tag="VVR43_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEU6150399.1"
                     /translation="MTSKLTASTCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIE
                     IKQFKVTVITEPDAKTQSR"
     gene            complement(23048..23401)
                     /locus_tag="VVR43_002124"
     CDS             complement(23048..23401)
                     /locus_tag="VVR43_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6150400.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
BASE COUNT         7678 a         4357 c         4596 g         7035 t
ORIGIN      
        1 ataattgact gaataaacta catatgttag aataaaaaca aggaaaaaga aaggggtttc
       61 attgcatgag aaaaaaacgt ggaattaaaa aattagttac atttgcatta ctaggtgttt
      121 ttatgtttag taatacaatt ccttaccaac agtttattca gaagaataaa caattggaag
      181 ttcgagtaca atcacaaaag gagtccaatg gtcttgatgt tgggaaggct gattagttga
      241 ttaaatgatg aaaatactaa ttaactatat ggtatttctg ttttatctaa tttttaatta
      301 gaaaaatagc ataaaaatct agttatccgc ataaaaactg gacttatcac actttatcaa
      361 ggtcaaaacc actcaattta ctactaattt actacttatg aatgagcttt gatacgacga
      421 tttatccttg aaaagtgaag atataaagat acttccaata aaatttgaat atttaatagg
      481 tagacacttc aaaaaatgag gtgtctattt ttttacccga ttttgaaagg aagtgaactt
      541 atgaaaacaa aaaatcaaga atcaaaaggt cgttccccac tctttaagac catcaaacat
      601 tcattcagcc aataaaaaag aaaggatagg taaaaatatg gaacttaaat ttgtgattcc
      661 caacatggaa aaaacattcg gcaatttaga atttgctggc gaggataaag tcgttcagcg
      721 aagaatcaac ggacggctaa ctgtcttatc aagaagctat aatctctatt ctgatgttca
      781 aagagcagat gatattgtgg tggtgcttcc tgctgaagct ggcgaaaaac atttcggctt
      841 tgaggaacgt gtgaagttag tcaatccacg tattaccgca gagggctaca aaatcggcac
      901 tcgtggtttt acaaattacc ttttacatgc tgacgacatg ataaaagaat aaagaaagag
      961 aggaaaaatg atgagattag caaatggcat tgtattagat aaagacacga cttttggaga
     1021 attgaaattc tctgctctac gtcgtgaagt gagaatccaa aatgaagacg ggtcggtttc
     1081 agatgaaatc aaggaacgta cctatgactt aaaatccaaa ggacaaggac gcatgattca
     1141 agtaagtatt cctgccagcg tgcctttgaa agagtttgat tataacgcac gggtggaact
     1201 tatcaatccc attgcggaca ccgttgctac tgccacctat caaggagcag atgttgactg
     1261 gtatatcaag gcagacgata ttgtgctgac aaaggattct agttcattca aagctcaacc
     1321 acaagcaaag aaagaaccga cacaagacaa atagtcgcta ggtagaaagg agactttttc
     1381 gcatgaaaca gcgtggtaaa aggattcgcc catctggtaa agatttagtc tttcatttta
     1441 cgatagcgtc actcctgcct gttttcctgc tggttgtcgg actgtttcat gtgaagacaa
     1501 tccagcagat caactggcag gattttaacc tatcacaagc agataagatt gacattccct
     1561 atttaattat cagtttcagt gtcgcaattc ttatctgctt gctggtagcg tttgtattca
     1621 aacgggttcg ctatgatacg gttaaacaac tttaccaccg tcaaaaactg gcaaagatga
     1681 tacttgaaaa caagtggtat gaatctgaac aggtcaaaac agagggtttc tttaaagata
     1741 gtgctggtcg tacaaaggaa aagataacct acttccctaa aatgtattat cgacttaaaa
     1801 atggcttgat acagatacgg gtggaaatca cgctgggaaa atatcaagac caactcttac
     1861 acttggaaaa gaaattagag agtggcttgt actgtgagct gacggataaa gagttaaagg
     1921 attcctatgt ggaatatact ttgctctatg acaccatagc cagtcgtatt tctattgatg
     1981 aagtacaagc taaagatggt aaacttcgct taatgaaaaa cgtatggtgg gaatatgata
     2041 agctccctca tatgttgatt gctggtggta caggtggcgg taaaacttac tttatactga
     2101 cactgattga agccttgctt catacagatt caaaactgta tattcttgac ccgaaaaatg
     2161 ctgaccttgc ggacttaggt tctgtgatgg caaatgtcta ctatagaaaa gaagacttgc
     2221 tttcttgcat tgaaacattc tatgaagaaa tgatgaaacg tagtgaggaa atgaagcaga
     2281 tgaagaacta taagactggc aaaaattatg cttacttagg tctcccggca cacttcttaa
     2341 tctttgatga atacgtcgct ttcatggaaa tgctgggaac aaaagaaaac accgcagtta
     2401 tgaataagct gaaacagatt gtcatgttag gtcgtcaagc tggcttcttt ctaatactgg
     2461 cttgtcaacg tccagacgca aaatatttag gcgacggaat ccgtgatcag tttaatttca
     2521 gagtggcttt aggtcgtatg tctgaaatgg gctatggcat gatgtttggc agtgacgtac
     2581 aaaaggattt cttcttaaag cgaatcaaag gtcgtggcta tgttgatgta ggaacaagtg
     2641 tcatatcaga gttttatact ccccttgtac caaaaggata tgatttcttg gaggaaatta
     2701 aaaagttatc caacagcaga cagtccacgc aggcgacgtg cgaagcggaa gtcgcaggtg
     2761 tggactgatc ttgctggctg gtgtggcaat agccacgcca gcacttaacc ccccgtatct
     2821 aacagggggg tacaaatcga caggaaacag tcaaaaaaac attagaaaat cctttggtta
     2881 caagggattt acaaaatttc agcgtatgtc aaatgggctt taaaagttga catacgcctt
     2941 tttgattgga gggattttta ctgaatgaac aaacttggtt acagcagtta aaagaaaaac
     3001 gcttggctta tggactatct caaaatcgtt tagcggttgc gactggtatt acaaggcagt
     3061 atctaagcga tattgaaaca ggaaaagtca agccatcaga ggatttacag caatctcttt
     3121 ttgaagctct ggaacgcttc aatcccgacg ctccccttga aatgctcttt gattatgtaa
     3181 ggattcgctt tcccacaacg gacgtacagc atgtggtcga aaacatctta caactgaaac
     3241 tgtcctattt tcttcatgag gactatggtt tctattctta ttcagagcat tatgctttag
     3301 gcgatatatt cgttctctgc tcccacgaac tggacaaagg agttctggtg gaattgaaag
     3361 gtcgtgggtg tcggcaattt gaaagctatc ttctggctca acaaagaagc tggtatgagt
     3421 tctttatgga cgctttggtg gctggcggtg tgatgaaacg ccttgacctt gccattaacg
     3481 ataagacagg gattttgaat atccctgtac tcactgaaaa gtgccaacag gaagaatgta
     3541 tctccgtctt ccgcagtttt aaaagctatc gcagtggcga actggtacgc aaagaggaaa
     3601 aggaatgtat gggaaacacc ctctatatcg gttcattaca aagtgaagtt tatttctgta
     3661 tctatgaaaa ggactacgag cagtacaaga aaaatgatat tcccattgaa gacgcagaag
     3721 taaaaaaccg ttttgagatt cgattgaaaa atgagcgtgc ctattatgca gtccgtgatt
     3781 tactcgtcta tgacaatcca gagcataccg cctttaaaat tatcaatcgg tatatccgtt
     3841 ttgtagataa agacgattcc aaacctcgtt ctgattggaa actgaatgaa gaatgggctt
     3901 ggtttattgg gaacaatcgt gaacgattaa aactaaccac aaaaccagag ccttactcct
     3961 tccaaaggac gctgaactgg ctatctcatc aagttgcccc gaccttaaag gttgcgatta
     4021 aacttgatga aatcaaccag acgcaggttg taaaagacat tctcgaccat gcgaaactga
     4081 cagaccgaca caagcagatt ttgaagcaac agtcagtaaa agaacaggac gtgataacaa
     4141 caaaaaaagg atatctgtca accataccag ttgacagata tccaaaaaaa agatataatg
     4201 ggagataaga cggttcgtgt tcgtgctgac ttgcaccata tcataaaaat cgaaacagca
     4261 aagaatggcg gaaacgtaaa agaagttatg gaaataagac ttagaagcaa acttaagagt
     4321 gtgttgatag tgcattatct taaaattttg tataatagga attgaagtta aattagatgc
     4381 taaaaatttg taattaagaa ggagggattc gtcatgttgg tattccaaat gcgtaatgta
     4441 gataaaacat ctactgtttt gaaacagact aaaaacagtg attacgcaga taaataaata
     4501 cgttagatta attcctacca gtgactaatc ttatgacttt ttaaacagat aactaaaatt
     4561 acaaacaaat cgtttaactt ctgtatttgt ttatagatgt aatcacttca ggagagatta
     4621 catgaacaaa aatataaaat attctcaaaa ctttttaacg agtgaaaaag tactcaacca
     4681 aataataaaa caattgaatt taaaagaaac cgataccgtt tacgaaattg gaacaggtaa
     4741 agggcattta acgacgaaac tggctaaaat aagtaaacag gtaacgtcta ttgaattaga
     4801 cagtcatcta ttcaacttat cgtcagaaaa attaaaactg aatactcgtg tcactttaat
     4861 tcaccaagat attctacagt ttcaattccc taacaaacag aggtataaaa ttgttgggaa
     4921 tattccttac catttaagca cacaaattat taaaaaagtg gtttttgaaa gccgtgcgtc
     4981 tgacatctat ctgattgttg aagaaggatt ctacaagcgt accttggata ttcaccgaac
     5041 actagggttg ctcttgcaca ctcaagtctc gattcagcaa ttgcttaagc tgccagcgga
     5101 atgctttcat cctaaaccaa aagtaaacag tgtcttaata aaacttaccc gccataccac
     5161 agatgttcca gataaatatt ggaagctata tacgtacttt gtttcaaaat gggtcaatcg
     5221 agaatatcgt caactgttta ctaaaaatca gtttcatcaa gcaatgaaac acgccaaagt
     5281 aaacaattta agtaccatta cttatgagca agtattgtct atttttaata gttatctatt
     5341 atttaacggg aggaaataat tctatgagtc gcttttttaa atttggaaag ttacacgtta
     5401 ctaaagggaa tggagataaa ttattagata tactactgac agcttccaag aagctaaaga
     5461 ggtccctagc gcctacgggg aatttgtatc gataaggggt acaaattccc actaagcgct
     5521 cgggacccct tgtaggaaaa tgtcctaagt gggatatctg tcaactggta tggttgacta
     5581 aaaatacttc ctacgaaaat gtagggggta tttttttacg aaaaaataca atcgattctt
     5641 aaaaagaaaa atttttgatt ggcaaaacca taacaagttc gttttagggt tttgattttg
     5701 cgattgatgc cttctaaagg accattagag tattcaaatt tagcgctatt taagacatat
     5761 tttctgtttt gacgaagggt ttgaatagca gtatccattt ctgtattggt tttttggtag
     5821 tctaagatgg ttgactctag taattcacta ttgcgctcgt ttagggcttt cgtgatatct
     5881 tggtaagttt ggtatacttc agcgaacttg gaaaatttac tagtaatgag atcaacagca
     5941 ttttggcgag tcatatattg tttaacgccg cgaagaaaaa ctacttcttc agggtgaaga
     6001 tcttcagctt ttttatggaa tagcttccaa tgtgacttca taattttata ttcttggctc
     6061 tgtttatcaa gttgctttag gatagagata cgacaattgt ccaaagcgcg accagctaat
     6121 tgtacaaggt ggaagcgatc aataatgata ttggcattag ggaaaaggcg atagataaaa
     6181 ctttgatatt gagcatttaa atcaattaca actgattgaa cgcattcgcg ttcggctttt
     6241 gaataacgac tttcaaaata atcaacaatg gtaggtgata gacgatcctg taactttgtg
     6301 acaatttggt gggtttcagc gtcacaacag ataaaggaca tcacagactt aattgaacga
     6361 aactcgtcaa aacatagatg cttaggcaac ttagccacac gatagtgtgg ttccatgcgc
     6421 tctaagattg ttcgacgaac actgctagga gagcagtgac acatttcagc aataagctga
     6481 ccagataagc ctttacgagc taaaagcatg atttgatttt tgagatcact ggataaggtt
     6541 tgattttctt tggttaaatt agtaatagca ccaaaagtag tatggcatga tttacattta
     6601 tagcgttgtt tacgaagctc tagttcatat cttctcccat ttaaacttgc cagtcgtaca
     6661 tgagttttgc gaaagccatc cttattaact gtgggaaagc cacagttacg acaacgatta
     6721 atcggataag aaagagtagc tgttattagc gttatatact ctttaacaga atcgttgttg
     6781 tgttcagctt cttcaacaga aataatttta atatttttat ctttaattcc aagaatattt
     6841 aggatagaat cattatggga catttgttta accttctttc atgatttttg tggtgaattg
     6901 attgtataac gaggggacag caaatgtcct cttttttgta taaaaaaatc tggcatggaa
     6961 tctctatcca taccagaaag tgtatacccc aaaaaaataa ctcaaataca aattcattga
     7021 atatagagag gagaacattt ttatgaattt tggacaaaac ctttataact ggtttctatc
     7081 aaacgctcaa tcactggtgc ttttagcaat cgttgtgatt ggcttgtatc ttggcttcaa
     7141 gcgtgagttt agcaaactga ttggcttttt aattattgcg attattgcgg ttggcttagt
     7201 cttcaacgct gctggagtaa aagacatttt actagagcta ttcaatcgca ttattggtgc
     7261 ttaaataaaa ccgttctttt gtggaatata agtggttttc ttatgttccg caaaggaatg
     7321 gtacaccaaa cgaagtgcgg tagggatttt tgaatctcta caaagaaagg acgtgaatat
     7381 atggacgata tgcaagtcta tattgcgaat ttaggcaaat acaatgaggg cgaattggtc
     7441 ggtgcgtggt ttacctttcc cattgacttt gaggaagtca aagagaaaat cggcttgaat
     7501 gatgaatatg aggaatacgc cattcatgac tacgagttac cctttacggt tgacgaatac
     7561 acttccattg gcgaactcaa tcgactatgg gaaatggtat cggaattacc cgaagaatta
     7621 caatcggagc tatctgctct gctcactcat ttttcaagca ttgaagaact aagcgaacat
     7681 caagaggata ttatcattca ttccgattgt gatgatatgt atgacgtggc acgctactac
     7741 attgaagaaa cgggtgcttt aggcgaagta ccagctagtc ttcaaaacta tattgattat
     7801 caagcctatg gtcgggattt agacctttca ggaacgttta tctcaaccaa tcatgggatt
     7861 tttgaaatcg tctattaaat ctgtcggtac attactactg gcagattttc tattttacgg
     7921 ggtggctcaa tcagctaccc ctatttttta tgaaaggatt gattacatga agaaaatacg
     7981 aagctatacc agtatctggt ctgtggaaaa ggtactgtat tctatcaatg attttagact
     8041 tccgtttccc ataaccttta cgcaaatgac atggtttgtc gtgtcactct ttgcagtgat
     8101 gatacttggc aacttgcccc ctctttccat gatagaggga gcatttctca aatactttgg
     8161 gattcctgtg gctttcacat ggtttatgtc tacaaaaact tttgatggta aaaagcctta
     8221 tggatttttg aagtctgtca ttgcttatgc actgcgacca aagctgacct atgcaggaaa
     8281 aaaagtaacg cttggcagaa accagccaca agaagccatt acagcagtta ggagtgaatt
     8341 ttatggcata tccaattaaa tacattgaaa acaatctcgt ctggaataaa gacggggaat
     8401 gttatgctta ctatgagctt gttccttaca attactcatt tctaagtcca gaacagaaaa
     8461 tacaagtgca tgattctttc agacagctta tcgcacaaaa tcgtgatggc aaaattcatg
     8521 ctttacaaat cagtacagaa tccagcatac gttctgcaca agagcgttcc aaaaatgaag
     8581 tcactggcaa gctcaaagcg gttgcctatg acaaaatcga ccaacagaca gacgctttaa
     8641 tatccatgat tggcgaaaat caagtgaact accgtttctt tatcggcttt aagttgcttc
     8701 tcaacgatca ggagttttct atgaaaagtc ttaccgttga agcaaaaaat gctttgtctg
     8761 attttgtcta tgatgtgaac cataagctga tgggcgattt tgttagtatg agtaatgatg
     8821 aaatcctgcg ttttcagaag atggaaaagc tcttagaaaa taaaatctct cgtcgtttca
     8881 aaatccgcag gttagataag gacgacttcg gctatctgat tgaacacctt tacggacaga
     8941 caggcactgc ctatgaagag tatgagtacc atctatcaaa gaaaaagctg gataatgaaa
     9001 cgctgattaa atactatgac ttgattaagc ctactcgctg tttggtggaa gaaaaacagc
     9061 gatatttgaa aatccagcag gaagatgaaa ccgtctatgt agcttacttt accattaaca
     9121 gcattgtcgg agaactggac ttcccgtcct ctgaaatctt ctactaccag caacagcaat
     9181 ttacattccc gattgatacg tcaatgaatg tggaaattgt agcgaatcgt aaagccctat
     9241 ctactgtccg caataaaaag aaagaactga aagacttgga taaccacgca tggcaaagtg
     9301 ataatgaaac cagctctaat gtggcggaag ctctggaaag tgtgaacgag ctggaaacca
     9361 atttagacca aagcaaggaa tctatgtata agctgtccta tgttgtaagg gtatcagcaa
     9421 atgaccttga cgaacttaaa cgtcgttgta atgaagtgaa agatttctat gatgatttga
     9481 gcgtgaaact ggtacgacct tttggggata tgctgggctt acatgaagaa tttttacctg
     9541 ccagcaaaag atatatgaat gactatattc aatacgtgac ctctgatttc ctcgctggtt
     9601 taggttttgg tgctactcaa atgctgggtg aaaatgaggg gatttatgtt ggctacagct
     9661 tagatactgg acgcaatgtc tatctgaaac ctgctcttgc cagtcaaggg gttaagggtt
     9721 cagtaaccaa tgcgttagcg tctgcctttg tcggttcgct gggtggtggt aaatcctttg
     9781 cgaataacct tatcgtctat tatgcagtgc tttatggggc acaagcagtg attgtagacc
     9841 caaaagcaga acgtggcaga tggaaagaaa ccttgccaga gatttcccat gaaatcaata
     9901 tcgtcactct gacttctgat gagaaaaaca aaggcttact tgacccttat gtgattatga
     9961 aaaatcccaa agattctgaa tcactggcta ttgatattct gacattcctt acggggattt
    10021 cctctcgtga tggggaacgc ttcccaatcc ttagaaaagc cattcgtgca gtaaccaata
    10081 gtgaagtacg agggttgatg aaagtgattg aggaattacg ggttgagaat acgccactaa
    10141 gtaccagtat agccgaccat atcgaaagtt ttacagacta tgactttgca catttattat
    10201 tcagtaatgg ttatgtggag cagtctatca gcttagaaaa acaactgaac attatacagg
    10261 ttgcggactt ggtacttccc gacaaggaaa cttcctttga ggaatatacc actatggagc
    10321 ttttatccgt tgctatgctg attgtcatta gtacctttgc tttagacttt atccatacag
    10381 accgaagcat tttcaagatt gtagatttag acgaagcatg gagcttttta caggtagcac
    10441 aaggaaaaac actatctatg aagctggttc gggctggtcg tgctatgaac gctggggtat
    10501 atttcgtgac ccaaaataca gacgacctct tagatgaaaa actgaaaaat aacctcggct
    10561 taaaatttgc atttcgttcc actgacctta acgagattaa aaagacctta gccttttttg
    10621 gtgtagaccc agaggacgaa aacaatcaga agcgattgcg tgatttggaa aacgggcaat
    10681 gccttatcag tgatttatat ggtcgtgtcg gtgtgataca gttccaccct gtatttgaag
    10741 aactgctcca tgcctttgat accagaccac ctgtgcgaaa agaggtgtaa atgtgaaacc
    10801 atcaatagta aacagaataa aatcaaactg gacgctgaaa cgtctaggta aagtggcaat
    10861 gacagtggct ttcacacttg tgattgccat ttttctttta gccatgctgg gaacggtggt
    10921 tcaagctgcg ggcttggtag atgatacggt caatgtggca aatgaataca gccgataccc
    10981 acttgaaaac tatcaactgg atttttatgt ggataatagc tggggctggc ttccgtggaa
    11041 ctggtcggac gggattggaa aacaggtcat gtatggacta tatgccatta ccaattttat
    11101 ttggacaatc agtttgtatg tttccaatgc gacaggttac ttagtacagg aagcctattc
    11161 cttagacttc atttccgcta cagcagattc cattggtaag aatatgcaga ccttagctgg
    11221 tgtgagtgca aacggatttt caacagaggg tttctatgtt ggattcctct tactcttgat
    11281 tttggttctt ggggtttatg ttgcctatac gggactgata aagagagaaa ccacaaaggc
    11341 aattcatgcc attatgaatt ttgtgctggt gtttatccta tcggcttcct ttattgccta
    11401 cgctcccgac tacattaaaa aaatcaatga cttttcatca gacatcagta atgccagttt
    11461 atcacttggc acgaagattg tcatgcccca ttccgatagt caaggcaagg acagcgtgga
    11521 cttaatcaga gatagcctgt tttccataca ggttcagcaa ccgtggctac tgcttcaata
    11581 caacagttca gacattgaaa gtatcggtat tgaccgtgtg gaaagcctgc tctccaccag
    11641 cccagattcc aacaatggcg aagacagaga aaaaattgtt gcggaagaaa ttgaagacag
    11701 aagcaatacc aatctaacca ttacaaagac cattaaccgt ttaggtacag tcttcttcct
    11761 atttgtcttc aatattggga tttccatatt tgtattccta ttaacaggaa tcatgatttt
    11821 ctcgcaggta ctttttatca tctatgctat gtttctgcct gtgagcttta ttttaagcat
    11881 gattccatca tttgatggta tgtcaaaacg agccataaca aagctcttta ataccatttt
    11941 gacacgagct ggaatcacat tgattattac gacagcattt agtatttcaa ccatgctcta
    12001 taccttatcg gctggttatc cgttcttttt gattgctttt ctacagattg tgacctttgc
    12061 aggaatctac ttcaagctgg gcgatttaat gagtatgttt tctctacaga gtaacgattc
    12121 tcaaagtgtg ggaagtcgtg tgatgagaaa acctcgtatg cttatgcacg ctcacatgca
    12181 ccgtctacag cggaaacttg gacgttccat gactactcta ggggctgggt ctgccattgt
    12241 tacaggtaaa aaaggacagt cgggttcggg gagttctgca aggacacaag cagatcactc
    12301 ccgaccagac ggaaaggaaa aatcaacact tggaaaacgt atcggtcaaa ccatcggtac
    12361 agtagctgat accaaagaca gaatggtaga cactgctagt ggtttgaaag aacaggttaa
    12421 agatttgccg accaatgcaa gatatgcagt atatcaagga aaatccaaag taaaagagaa
    12481 tgtccgtgat ttaaccagta gtatttctca aaccaaagcg gaaagagcca gtggacgcaa
    12541 ggaacagcag gaacaaaggc gaaaaaccat tgcgaagcgt cgctctgaaa tggaacaggt
    12601 caaacagaaa aaacagcctg cttcttctgt tcatgaaaga ccgactacaa gacaagaaca
    12661 atatcatgat gaacagacct caaaacagtc taatattcag acttcatata aggaatctca
    12721 acaagccaaa caagagcgtc cagcagttaa gtccgatttt tcaagtccaa aagtggaacg
    12781 ccaaggcaat accgttcaag aaaaaaccgt tcaaaagcca gcaacttcaa ccactacagc
    12841 agatagaact tcacaacgtc caatcacaaa agaacgtccg tctactgttc aaagagtacc
    12901 actacaaaat acaagaagta gaccaccaat caaaaccgcc accattaaga aagtcggtaa
    12961 gaaaccatga agttgaaaac tttagtgatt ggtggttctg gattattctt gatggtcttc
    13021 tcactgcttc tgtttgttgc cattttattt tcagatgaac aggacagcgg aatttccaat
    13081 attcattatg gaggtgtgaa tgtttccgca gaagtgctgg ctcataagcc tatggtagaa
    13141 aaatatgcca aagaatatgg cgttgaagaa tatgtcaaca tacttcttgc gattatacag
    13201 gtggaatcgg gcggtactgc ggaagatgtt atgcagtcct cggaatccct cggtcttcca
    13261 cctaattcat tgagtacaga agaatccatt aagcaaggtg tgaagtattt cagtgaatta
    13321 ttagccagta gcgaaaggct cagtgtagat ttagaatcgg ttatccagtc ctacaattat
    13381 ggtggtggtt tcttagggta tgtggctaat cgtggaaata aatatacctt tgaactggct
    13441 caaagtttct caaaagagta ttcaggtggc gaaaaagtgt cttaccccaa tcccatagcc
    13501 atacctatca atgggggctg gcgatacaac tatggcaata tgttttatgt gcaactggta
    13561 acgcagtatc ttgtcacaac agagtttgat gatgatacgg tacaagccat catggacgaa
    13621 gcactgaaat atgagggctg gcgatacgtt tacggtggag cttccccgac tacttctttt
    13681 gattgtagcg gactgacaca atggacgtat ggaaaagctg gaattaactt accacgaacc
    13741 gcacaacagc aatatgatgt gacccagcat atcccactat cggaagcaca agctggcgat
    13801 ttggttttct ttcattctac ctataacgct ggctcttata ttactcatgt tgggatatac
    13861 cttggcaata accgtatgtt tcatgcaggc gacccaatcg gttatgccga cttaacaagc
    13921 ccctactggc aacagcattt agtgggagca ggacgaatca aacaatgaga aaggaagatt
    13981 taatgatgaa atttagaaaa aatcagaata aagaaaaaca gataccaaag gaaaagaaac
    14041 ctcgtgtcta taaggtcaat cctcataaaa aggttgtgat tgccttgtgg gtacttttag
    14101 ggcttagttt cagctttgcg atattcaagc actttacagc tatagatact catactattc
    14161 acgaaacaac tatcatagaa aaggaatacg ttgatactca tcatgtagaa aattttgtag
    14221 agaactttgc gaaagtctac tattcatggg agcaatccga taagtccatt gataatcgaa
    14281 tggaaagtct aaaaggctat ctgacagatg aacttcaagc tctcaatgtt gatacagtac
    14341 gcaaagatat tcctgtatcg tcttctgtaa gaggatttca gatatggacg gtagagccaa
    14401 ctggcgacaa tgagtttaat gtaacctaca gtgtagacca gctcattaca gagggagaaa
    14461 atacaaagac cgtccactct gcttatatag tgagtgtcta tgtagatggt tctggaaata
    14521 tggtactggt taagaatccg accattacca acatacctaa gaaatcaagt tataaaccaa
    14581 aagccattga aagtgagggg acggttgatt ccattacaac caatgaaatc aatgagtttt
    14641 taacgacgtt cttcaagctc tatcctacag cgacagccag tgaactttcc tactatgtga
    14701 atgacgggat attaaaacca atcggaaaag agtacatctt tcaagaactg gtaaatccta
    14761 ttcacaatcg taaggataat caagtcacgg tatcgctgac agtggagtat atcgaccagc
    14821 agaccaaagc aacgcaggta tctcaatttg atttggtact tgaaaagaac gggagtaatt
    14881 ggaagattat agaataacaa atattggtac attattacag ctattttgta atcacgtact
    14941 ctctttgata aaaaattgga gattccttta caaatatgct cttacgtgct attatttaag
    15001 tatctattta aaaggagtta ataaatatgc ggcaaggtat tcttaaataa actgtcaatt
    15061 tgatagtgcg aacaaataat tggatgtcct tttttaggag ggcttagttt tttgtaccca
    15121 gtttaagaat acctttatca tgtgattcta aagtatccgg agaatatctg tatgctttgt
    15181 atgcctatgg ttatgcataa aaatcccagt gataagagta tttatcactg ggatttttat
    15241 gcccttttgg gcttttgaat ggaggaaaat cacatgaaaa ttattaatat tggagtttta
    15301 gctcatgttg atgcgggaaa aactacctta acagaaagct tattatataa cagtggagcg
    15361 attacagaat taggaagcgt ggacaaaggt acaacgagga cggataatac gcttttagaa
    15421 cgtcagagag gaattacaat tcagacagga ataacctctt ttcagtggga aaatacgaag
    15481 gtgaacatca tagacacgcc aggacatatg gatttcttag cagaagtata tcgttcatta
    15541 tcagttttag atggggcaat tctactgatt tctgcaaaag atggcgtaca agcacaaact
    15601 cgtatattat ttcatgcact taggaaaatg gggattccca caatcttttt tatcaataag
    15661 attgaccaaa atggaattga tttatcaacg gtttatcagg atattaaaga gaaactttct
    15721 gccgaaattg taatcaaaca gaaggtagaa ctgtatccta atatgtgtgt gacgaacttt
    15781 accgaatctg aacaatggga tacggtaata gagggaaacg atgacctttt agagaaatat
    15841 atgtccggta aatcattaga agcattggaa ctcgaacaag aggaaagcat aagatttcat
    15901 aattgttccc tgttccctgt ttatcacgga agtgcaaaaa acaatatagg gattgataac
    15961 cttatagaag tgattacgaa taaattttat tcatcaacac atcgaggtca gtctgaactt
    16021 tgcggaaaag ttttcaaaat tgagtattcg gaaaaaagac agcgtcttgc atatatacgt
    16081 ctttatagtg gcgtactgca tttgcgagat tcggttagaa tatcggaaaa ggaaaaaata
    16141 aaaattacag aaatgtatac ttcaataaat ggtgaattat gtaaaatcga taaggcttat
    16201 tccggggaaa ttgttatttt gcagaatgag tttttgaagt taaatagtgt tcttggagat
    16261 acaaagctat tgccacagag agagagaatt gaaaatcccc tccctctgct gcaaacaact
    16321 gttgaaccga gcaaacctca acaaagggaa atgttacttg atgcactttt agaaatctcc
    16381 gacagtgacc cgcttctgcg atattatgtg gattctgcga cacatgaaat catactttct
    16441 ttcttaggga aagtacaaat ggaagtgact tgtgctctgc tgcaagaaaa gtatcatgtg
    16501 gagatagaaa taaaagagcc tacagtcatt tatatggaaa gaccgttaaa aaaagcagag
    16561 tataccattc acatcgaagt tccaccgaat cctttctggg cttccattgg tttatctgta
    16621 tcaccgcttc cgttgggaag tggaatgcag tatgagagct cggtttctct tggatactta
    16681 aatcaatcat ttcaaaatgc agttatggaa gggatacgct atggctgtga acaaggattg
    16741 tatggttgga atgtgacgga ctgtaaaatc tgttttaagt atggcttata ctatagccct
    16801 gttagtaccc cagcagattt tcggatgctt gctcctattg tattggaaca agtcttaaaa
    16861 aaagctggaa cagaattgtt agagccatat cttagtttta aaatttatgc gccacaggaa
    16921 tatctttcac gagcatacac cgatgctcct aaatattgtg cgaacatcgt agacactcaa
    16981 ttgaaaaata atgaggtcat tcttagtgga gaaatccctg ctcggtgtat tcaagaatat
    17041 cgtagtgatt taactttctt tacaaatgga cgtagtgttt gtttaacaga gttaaaaggg
    17101 taccatgtta ctaccggtga acctgtttgc cagccccgtc gtccaaatag tcggatagat
    17161 aaagtacgat atatgttcaa taaaataact tagtgtattt tatgttgtta tataaatatg
    17221 gtttcttgtt aaataagatg aaatattttt taataaagat ttgaattaaa gtgtaaagga
    17281 ggagatagtt attataaact acaagtggat attgtgtgct gagagctttc ttctatacta
    17341 atagacgaaa gggtgtgaaa atgattttta aatgatactg tggaacggaa cagtagccct
    17401 agtattgact actgtcgttt ctattcatat tggctattct aggactgaga tgaaaaaatc
    17461 tataaatgct cagaataaaa ttgaacccgc aaatctcccc aaaacaatgg tgagtcatgt
    17521 acttgtatta ttccgaaaaa atacacctct ggtgcagtga gacaaattgg tgtatcttat
    17581 agtggcttcg tagatgaaag ctatactcta ctatcactct ttgatgatgt agaacaaatt
    17641 gaaaaagata atagacttca gacagctatt gatgttgtca gagaacagtt tggtttttta
    17701 gccatacaaa aaggaaccgt cctaactgaa ggttccagaa atattgaacg cagtaaactt
    17761 atcggtggtc attccgcggg tggattggag ggattaaaat gaaacaagaa aaaaatacag
    17821 tacaattttc agaaatccgt agcaaaggat gtaatgatat tgaaatgctt gaaagatttt
    17881 tacatggaat cgttgaaaca gcaacttcaa aacttcgtca gagaaaactc aaaacaactg
    17941 aaatatcgat acgactagta catgctaaat ctgaaaaccg attaccattg gaatttacat
    18001 ttagcattaa gccaacaagc tcatctgtga taatctatac tgaggtaatc aatcgcttta
    18061 aagaatgtta cacaggtggg ggaattcaag gttttacgat tcaatttgat aaaaataccc
    18121 ttgcctctgc atagaaagga tttgatatga ttgaccgttc atatttacca tttcaatcag
    18181 caagagagta ccaggataca aagatgcaaa aatggatggg ctttttccta tctgaacatg
    18241 catcagcact ctctgatgat acaaacaaag taacgtacat gtctgactta tcactagaga
    18301 agaaattatt actcctcagt caagtatacg ccgggcagct acgcacacgc attcaagtga
    18361 ttgaaaaaaa caagcgtgtt tcctacactg gaacaatacc aagtctgacc aaagatttca
    18421 ttttgataaa aactacaaca ggtcacatca atttgaaatt aaaagacatt attagtattg
    18481 aacttgtcga ggaggtgctc tatgaatcag cttgagtttc agcgtaatca cctacaaatg
    18541 gactattata gcgagagcta ccaagatttt gaacgtgact tctaccgcta ctctaacatg
    18601 aatattccat tgaccttcct aactgatgat atcctaaaaa caatggcgac ttcacgtaag
    18661 aattactttg tcctcaataa ggaaaagtcc agagataacc gcgatcactt cttcatattt
    18721 gaagtaagta ccgtagatga gaatccgcta atctatcatt atacatataa gaaaactaca
    18781 atatatttag cagaaaaata ggagcagttc aattgactgt tcctattttt aatattcata
    18841 aaatctaaag tctttatact ctttaacaat ggagtcgcca accagaacag actatactga
    18901 ccagcgacta ccttaaattt aatgtttcag atttattttc ttatctctaa tttcataaac
    18961 tacatctgct acattttcga gtaatcgttt atcgtgggtg ataaacacga tagttccggt
    19021 gtactccttc attagtattt ccaaagcctc taaacttggt atgtcaagga agttactggg
    19081 ttcatccatt attaggatgt tatatctacc catgagcatt ttagcaagca acaattttat
    19141 aatttctcca ccgcttaaaa cagataaact ttttccaata tcgttctgtt tgaaccccat
    19201 agatgctagc actgaacgaa tttctgatat attgtagtca caatccttct gcataaactc
    19261 cataacattc tgattactgt tgtacttgta accattctgt gcaaagtaac ctatttttgc
    19321 cttaggcgaa atagaaattc cttcttcatg gtttaagatc atttggatta aagttgtttt
    19381 tccgattcca ttaccaccag ttaacgccac ttttgctcct aacggaattt gaaaagatgc
    19441 attttcaaac agagccttat ccccaaatac tttattaatt tctgcaccga ctatagggta
    19501 tggattatgg agctccaatg ctttactttg cctgaaacga attctgcgaa tgccttccgg
    19561 agcttctact tttcctaagg ccgcaatcct gtgctctagg gttttagcag cattatacat
    19621 ctttttttcc ttacttccta ttgatttttg atgagctaaa cgccctccgt cttcagtact
    19681 ttttttcttt gaagaacctt ttgccttctg ttctatttta cgagcctgtt ttcgcttttc
    19741 ctccgcagcc ctttccaatc gggcacgttc cgcaataaat tgttcgtatt ctgcagcttg
    19801 gctcttacgt tcttcctctt tctgacgaag ataatcagaa tagtttcccc aatactcagt
    19861 gattttgcca tctttcagtt cccatatttt atctactatt tcatcaagaa aatagcggtc
    19921 atggctaata actaacagtg cacctgtaaa atattttagc tgtcctatta gaaaatcaat
    19981 tccttcacgg tctaaatggc tcgtaggttc atccgctaaa ataccatgaa cctgtgccga
    20041 taaggcctgt gctattttaa gccttgtttc ttcaccaccg ctcatagtct gtatatttaa
    20101 ttgctcaaca cctagcttgc ctacaagtgc aaaatctttt tcctcctgca gagttacttc
    20161 gtccaactgg ggaatatagg caagttcacc cagacgattc attttacatc ctgggggagt
    20221 taattctcct aaaagtaccc tgagtaaagt gctttttcca gcaccatttg ctcctactaa
    20281 accaatacgg tcataatcat atacttctaa ttcatttata tctaaaacat cgcgtccttt
    20341 gaattccaca cgaatgtctt ttgcttttaa tattaattcc ataacatttc ctcctgtcta
    20401 taatcgcatg ctttcatttg cttgtatgca gggaaaaccc tgcgatttta gcaggaagag
    20461 ttacatgaaa ataagataca taaatattcc tccaatattg tttattttaa atctaatttt
    20521 ctaacctcag ttatcatttg gcaaactata gcaatgccaa taattaaaat acctgatagt
    20581 aaaaaccaat gatttacacc gattttatca gcaaagaatc cagaaagaat taacccaatt
    20641 ggcatagcaa gtgacatgat acttccgatc aaagaaaata cacgtcctaa atattcaggc
    20701 ttaattttct cctgaaaaag agctgtttgc acaccgctat aaaatggcac cgaaagcccc
    20761 attattgcac agcaaactac gaatattaca aatccatttg gaggaagtat tcccgaaacg
    20821 gctaaactgg tccccattat aaaaaatgaa cttgttatta gtaatacatg cttttcgaag
    20881 ccccctaatc ttcctaataa taagcctcct gctagcatcc caaatgcaaa ggaaatttcc
    20941 gtaatagaaa tatgcacagg cgttccatta aagtgttcca tgcttattaa aggaaatagt
    21001 gcattgattg gcatataaac aaaagtatat agtgttccta agagtaataa ggcaaacaat
    21061 cctttgtttt gtctcagaac cacaactcct tctttcatct cccttatgaa atttggttct
    21121 aaactttgca cttgattacc cagcttaggt atacgtacaa ttgctaccgt aatagatgca
    21181 atcacagcac ccaatacgtc gatggcaata atagcattta aatcccaaac ggagtataag
    21241 agtgctgcaa ctgccggact aacaatatag cttatagact gcaaagactg actatagcct
    21301 gcgcatttcg ttagctgttc ttctggtact aaaagtggtg taaccgcatt gagtgctggg
    21361 gtatgaaaag ctgttccaat gctacggata aacaatacta tcataatcat ccagacaggt
    21421 agctccatac agaatgcaac aatagcaagc actgcaccag ctgctgcgat aattaaatcg
    21481 gcaccaatca ttatcttctt cctatcatga cgatccacta gcacaccaat ggcaggtccc
    21541 aaaatcgcat agggtaaaaa acctactaat gaagccatag acaagaccat cgcagatcct
    21601 gttttttctg taaggtaaaa aataatcgcc atttgcagga tggcactagt gattaatgat
    21661 actgcttgcc ctgcccatat tgcataaaat tttcgtttcc aattgttgta tttttccatt
    21721 tatattatct cctgcatatt attttgcttg aatttctatt ttgaatagca ttctaggcaa
    21781 taaaaaatgc aggccaaacc ccacaatgtg gcttttggtc tgcatacata caatttggaa
    21841 acattcatat taaagacata gttaaataaa ggtatagtta aataaccaat atcctcaccg
    21901 taactaatga atgctcaata tcgtataaat aagcacaaca aaaaagccta tcatcgggta
    21961 tagattctgc tttttttatt gccagcttat cttaaacgca ttgaggctgt catagtttcg
    22021 gttcctccta catctttgtt tatatcaatt tatagtataa cacaacaaga tgatatgttc
    22081 aatataaaag ttatggaatg agactcatac ttccaattcg atgccagatt taaaggatat
    22141 gacgaagttt tcttcataga ctgtaacgct ctggattatc ttccttagta gcaagcgatt
    22201 agctttcaca aaatcttctg tttgtagttt taaaaattca tcaggatttt ctaactcaac
    22261 ctcaaaatat ttcattttac attccctcat ttcatttatt gataaattga gtttgcaaaa
    22321 aagagtggac aatttttgtc tactcttaac ctttaaaata gtttttttta atcgatttga
    22381 agttgcctaa attattactt attcggtaaa atgaagtatt gctttcaaca gatttccttc
    22441 aactacactt cacttgattc aaacaaggtg ggtacatttc tattcccaca aactccttgt
    22501 caatggaaac aaacacgtac ccacagggta aatggaaata gaaactgata atttctagct
    22561 atcacttcta ctcattccaa aaattttctc actctgatac ttacccacca taaagcaaaa
    22621 agccttgcaa tcaaggcttt cattatccct ttcgttcaaa ggtttctaag cttttacgag
    22681 cagagcgaca cactcagcgg ttcgctatct ccgttctgtc tgcgtgctag cacttgtcaa
    22741 tcacggacag ctatcgcatg ggcggaagta aatgctaatc ttcgtcgttt tactccttga
    22801 ctagcaaact taccgcctca acatgtcctg tatgtggaaa taaaacacga ttaaagataa
    22861 gggaagatac tgaattaaaa aaattccccc tctattgtcc gaaatgcaga caagaaaatt
    22921 taattgaaat aaagcagttc aaagtaactg tgattacaga gccagacgca aagacgcaga
    22981 gccgataaaa tgagattaat acaatctcat tttatcggct ctttccgtta tgtatggatt
    23041 cttttaatta gtcttcgatg tttcttgctt cgttgatacc gctggctaaa gattccatta
    23101 aggatagttc tttgtctgta aagctatcca tgtatttctc tatctgtaat cgtcgggtgc
    23161 tttttaccaa gttattagca ggtaagaaaa attcatcaac ggaaacatga agtaacgata
    23221 caaggtcata aagaacttgt atgctggggt gttgcccttt attttcaata ttagttaagt
    23281 accgtgggtc aatttcaatc aatgctccca cttgttcacg agttaaacct cgtttcaatc
    23341 gagcttcttt aatggctaaa ccaaaggctc taaaatcata tttatcttct tttttacgca
    23401 tagtagacca cctctataca ttttattgtt cctactgaat taaaaacagg tatagaaaaa
    23461 cgtgttatat ggtttatagg tttatattta ataaaaagca ctactaaacg ccaataaaaa
    23521 aaaccgttat atggtagtgc tatttacgct gttaaaatat tgtatattac ttccaaatgg
    23581 cggtttgttg gaggtcaacg tcgccatgaa gtacatcata tacaataaat ttccttacat
    23641 tgggttcttg tcaaaaaaag tcgtct
//
LOCUS       DAVHSY010000125         5780 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254693-rid19266213.guided.072, whole
            genome shotgun sequence.
ACCESSION   DAVHSY010000125 DAVHSY010000000
VERSION     DAVHSY010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254693
            Sequence Read Archive: SRR2912536
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866601.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866601.1
            Genome Coverage       :: 208x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 01:51:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,091
            Genes (coding)                    :: 1,974
            CDSs (with protein)               :: 1,974
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 33
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 117
            CDSs (without protein)            :: 117
            Pseudo Genes (ambiguous residues) :: 0 of 117
            Pseudo Genes (frameshifted)       :: 63 of 117
            Pseudo Genes (incomplete)         :: 50 of 117
            Pseudo Genes (internal stop)      :: 33 of 117
            Pseudo Genes (multiple problems)  :: 26 of 117
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5780
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254693-rid19266213.guided.072"
                     /strain="Streptococcus species"
                     /serotype="19A"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2010-07-09"
                     /collected_by="Catrin Moore"
     gene            75..833
                     /locus_tag="VVR43_002125"
     CDS             75..833
                     /locus_tag="VVR43_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU6150401.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     ISEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKSYFEKNEIFKIQQDVIF"
     gene            891..1745
                     /locus_tag="VVR43_002126"
     CDS             891..1745
                     /locus_tag="VVR43_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU6150402.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMCISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            1857..2741
                     /locus_tag="VVR43_002127"
     CDS             1857..2741
                     /locus_tag="VVR43_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU6150403.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            2904..4643
                     /locus_tag="VVR43_002128"
                     /pseudo
     CDS             2904..4643
                     /locus_tag="VVR43_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
     gene            4918..5220
                     /locus_tag="VVR43_002129"
     CDS             4918..5220
                     /locus_tag="VVR43_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6150404.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKLVSINE"
     gene            5276..5704
                     /locus_tag="VVR43_002130"
     CDS             5276..5704
                     /locus_tag="VVR43_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6150405.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
BASE COUNT         1942 a          850 c         1217 g         1771 t
ORIGIN      
        1 ctcaaaaaaa taagagcaaa attgctatta ttttttacaa attggtgtaa cactagtgat
       61 ataggagtga tgaaatggtt gtttatatta gacaaagtaa attaccaagt gaggtttcaa
      121 ttaataaata caatgctcaa gtaggtgcct acttacaagg agaagaagtt attttatatc
      181 aatctttttc tgaaataaaa gagttaataa gtgaagatat agttgtagat tatataatgg
      241 agactagagc attactaaaa atgatgggct taaacgttcc ggtttatgac tatcctattg
      301 agcttaaaga gttttatggt cgaaagattt atgctggtat tttaggagag attgtgaata
      361 tacctgataa ttggggaaaa tttattaagc ctaaagctgg ttcaaaagtc tttactggaa
      421 gagttgttaa tggaacccat gatttaatag gtattggtct acctttcgac tatcctatat
      481 ggattagtga ggttgtagaa ttcatagctg aatggcgttg ttttgtgtta gatggtcgcg
      541 tattagatgt tcgaccctat acaggtgatt atcatgcaca atttgatgca agtgtaattg
      601 atgaagcgat atcatgttgg aaagatgcgc caatagctta tggactagat atcggtgtta
      661 ctcgcgatgg cagaacactt gttgttgaag taaatgatgg ttatgcattg ggaaattatg
      721 gcctatctcc tttaaaatca atcaattttc atagagctag gtggaaagaa atggtaaaat
      781 cctattttga aaaaaatgaa atttttaaaa tccaacagga tgttattttc taaaataaat
      841 atggtagata accaatataa aaagcatcaa aatgaacaag gaggaatctg atgcttggag
      901 caattattgg agatattgtc ggttctgttt acgaatggaa caatatcaaa acaaaggact
      961 ttcctttatt tcggaaggac tgctttttta cagatgacac ggttatgacc tgtgctgttg
     1021 cagaagcaat tatgaatggt ggacaaaaag acgatttcat tgacgcgatg aagaaatatg
     1081 gcagaatgta tccgaatgct gattacggtg ctcggtttaa tgcatggcta aacagcgata
     1141 accgtgagcc ttataatagc tttgggaatg gatcagctat gtgtatttct ccatgtgctt
     1201 ggatcatgga ctgtggtttt tatgcgaaaa ctggtatgtg gccatcatct agaggactta
     1261 cgagtctttc tgcagaggta actcataatc atccagaagg tgtcaaaggc gctatggcta
     1321 cagctgatgc tatctttcta tgtcgttttt actttggtgg ttattgtaga gagtacgagc
     1381 aatcaattaa cgacaatcct acagagtgta aaagacgaat taaggattat atagaaaaag
     1441 aatacgatta caatctatct caaactttag atgaaatccg tcctaactat cgttttaacg
     1501 aaacatgtca ggaaactgtc cctcaagcca ttatcgcctt tcttgaaagt agagacttcg
     1561 aagatgcgat aagaaatgcc atctcacttg gtggcgacag tgatactctc gcagcaatca
     1621 cttgtaacat agcagaggca gcttacggta ttcctgattg gatcaaggat aaggcctatt
     1681 cttacttgga tgaaccctta aaggatgtag ttaggcgatg ggaaaataga ataaaagcgt
     1741 attaatctcc agtacgtcag atttctcttt tctgtatttt cattgtataa taggattaca
     1801 tttacttgca tacgacgaaa tgtaaacatt tctgtttaaa attaaggata aaatcaatga
     1861 aaaaagcaat ggtaattatc aaccctactt ctggtggcga gaaggctttg gattacaaag
     1921 aaaagctgga gaataaagca aaagaatact ttgaatatgt tgaaaccaaa attaccgaaa
     1981 aagcgctgga tgcaacacat tttgctgaag aagcttctcg tgagcagtat gatgcagtgg
     2041 ttgtgtttgg tggagatgga actgtcaatg aagtcatttc aggtattgat gagagagact
     2101 acattcctaa gttagggatt atcccaggcg gtacgggtaa cctcattaca aaacttttgg
     2161 aaatcaatca agacatcgat ggcgcaattg acgaactgga ttttgattta accaataaga
     2221 ttgatatcgg taaagcaaat gacaactatt ttggttatat ctttagtatc ggttctctgc
     2281 ctgaggcgat tcacaatgtt gaaatagagg acaaaacaaa attcggtatt ttaacctatg
     2341 ctgtaaatac catgaagtct gtcatgacag atcaggtctt taacattaag gttgagacag
     2401 aaaatggaaa ttatgttggt gaagctagcc atgttttggt ccttttgaca aattacttcg
     2461 ctgataagaa aatctttgaa gaaaacaagg acggctatgc caacattttg attctgaaag
     2521 atgcctctat attctccaaa ttatccgtca ttcctgattt attaaaaggg gatgttatcg
     2581 caaatgataa tatcgagtat atcaaagcgc gtaatattaa aatctcttca gatagtgaat
     2641 tggagtcaga tgttgacgga gataaatcag ataacctacc tgtagaaatc aaagtcctag
     2701 ctcagcgagt agaagtattt tcaaaaccga aagaggatta gtatatagag aaagcctttt
     2761 ttaaggcttt ttgtatactt taaaagatag ttcctttaac aacggacatt ccttgcaaat
     2821 agtttacaaa aatagtatac tggattcatt gagtttgaaa acgtttgcgt aaaatttgaa
     2881 tgaatacttt aggagacaaa ttgatggaat tgagtgctat ttaccatagg cctgagtcgg
     2941 agtatgccta tctttataag gataagaaac tccatattcg aattcgaact aagaaagggg
     3001 acattgaaag catcaacttg cactatgggg acccttttat ctttatggag gagttttatc
     3061 aggatacaaa agaaatggtc aagataactt ctggtacctt atttgaccat tggcaggttg
     3121 aagtgtcagt tgactttgca cgtatccagt atctctttga gctcagagat acagaaggtc
     3181 aaaatatttt gtatggcgat aaagggtgtg tggaaaattc tctagaaaat cttcatgcaa
     3241 ttgggaatgg atttaagttg ccttatcttc atgagattga tgcctgcaag gttcctgact
     3301 gggtttcaaa tacggtatgg tatcagatat ttcctgaaag atttgccaat ggcaatgctc
     3361 tattaaaccc agaagggact ttagactggg attcatctgt cacacctaag agcgatgatt
     3421 tctttggtgg tgatttacag gggattattg atcatatgga ttacttgcaa gacttgggta
     3481 ttactggact atatctttgt cccatctttg aatctacaag caatcacaag tacaatacga
     3541 cagattactt tgaaattgac cgtcattttg gagacaagga gacctttcgg gaactggtgg
     3601 atcaagcgca tcatcgtggc atgaaagtca tgctggatgc ggtatttaat catattggtt
     3661 cgcaatctct tcaatggaaa aatgtcgtca aaaatggtga acagtctgct tataaggatt
     3721 ggttccatat tcaacaattc ccagtgacaa ctgaaaagct agttaataag agagacttac
     3781 cctatcatgt ttttggtttc gaggactata tgcctaagct aaatacagcc aatccagagg
     3841 tcaagaatta tcttttaaag gttgcgactt attggattga agagtttaat atcgatgctt
     3901 ggcgtttgga tgtggctagt gagattgacc atcagttctg gaaggatttt cgtaaggcag
     3961 ttttagctaa aaatcctgat ctttatatcc taggagaagt ctggcataca tctcagcctt
     4021 ggctaaatgg agatgagttc catgccgtca tgaattatcc tttatctgat agtatcaagg
     4081 actatttctt acgaggaatt aagaagacag accagttcat cgatgaaatc aattgagagt
     4141 ctatgtatta caagcagcag atttcagagg tcatgtttaa tctcttggat tcacatgata
     4201 cagagcgaat cctgtggacg gccaatgaag atgttcaact ggttaaatca gccttagcct
     4261 ttctctttta acaaaaagga acaccgtgca tttattacgg aaccgagcta gccttgactg
     4321 gaggaccaga tccagattgt cgtcgttgta tgccttggga acgtgtatca agtgacaatg
     4381 atatgctgaa ctttatgaag aggctgatta agattcggaa atacgcgtca gtaatcattt
     4441 cgcatggcaa gtatagcctt caagaaatca aatctgatct agtagctctg gaatggaaat
     4501 acgaaggatg gatcctcaaa gcaatattca accaatcaac agaagattat cttttagaga
     4561 aagaagcagt agcactagca agcaattgcc aagaattgga gaatcagctt gtcatctctc
     4621 cagatggatt tgtgattttc taaaaactag ttgatgaaga ttatggtaca tttcatatct
     4681 tatatagtat aataaggcta gttactaaac ttgtaaagga gaacttaaat gaattgtaga
     4741 ggacatgaaa caagacaaag aattgttaga gattttgaag tttagcctaa agcacatatt
     4801 aagctgttag caaatcaaca aaaacatagt gatgcaggag caactattga agatgaatat
     4861 tatgtattta tcgctgagag taaaattgat ggcaagaagg aagttattca gtgttgcatg
     4921 ggtgcggcaa gggatttttt agaactaatt aatcacaaag ggctacctct ttttaatccg
     4981 cttgtaggtg attctcatgt aaataataga caagaatatg acaatacagg gagtggaaat
     5041 ttacaacctg aaaagtggaa tgaaactgca aagcagcttt ataatgttat aatgtggttg
     5101 attattttat ggaatgctaa gccggataca cctttattta attttaaaga cgaagtaatt
     5161 aagtataaaa catatgagcc ttttgaaagc agtataaaat tggtatcaat caatgagtaa
     5221 caaagtatca gcatgattcg aaacatttac ttgtaatttg cggaggaaca tcaatatgga
     5281 tggaataaca aaagatttta taaaaacggc taaactaatg aaacaattat ggccccaatt
     5341 gaccgataaa gaagctattg atgaagtaaa aaaatatacg aatggcaaaa atactgcaat
     5401 ctttactgaa gttgaaggtg acacaattgt aggtctagca ctatgttcac tcagatttga
     5461 ttatgttgaa ggttgtaaat atagtcctgt tggattctta gaagggatta ttgttgacga
     5521 ggaatatcgt ttaaaggata ttgctaaaaa tctctgtaca aaatgtgagg aatgggcgaa
     5581 aaataaagga tgtaaggaat ttgcaagtga ctgtacttta acgaatacgg attctataag
     5641 atttcatctc aatattggat ttcaggaggc aaatagaatt attcatttta agaaaaaatt
     5701 ataatttaga aacgtgaata aacttgttta aactttatgt atctttagaa agtgtgttaa
     5761 cttgaaagaa caaatttttt
//
